Primary Site >> Colorectal Cancer
Gene >> NFKB1
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Ref: The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines. PMID: 8311838 |
Ref: Nuclear factor - kappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug. PMID: 9528861 Ref: Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy. PMID: 9796963 |
Ref: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways. PMID: 10866999 Ref: IkappaBbeta-related proteins in normal and transformed colonic epithelial cells. PMID: 11020244 Ref: Recent studies on the biofunctions and biotransformations of curcumin. PMID: 11237176 |
Ref: Mechanisms of cancer chemoprevention by curcumin. PMID: 11370761 Ref: Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells. PMID: 11412039 Ref: TNF and CD95 promote IL-8 gene transactivation via independent elements in colon carcinoma cells. PMID: 11500086 |
Ref: Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells. PMID: 11855750 Ref: Increased adhesion molecule expression in serosal fibroblasts isolated from patients with inflammatory bowel disease is secondary to inflammation. PMID: 11923606 Ref: PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway. PMID: 12360479 Ref: Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts. PMID: 12460899 Ref: Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. PMID: 12460901 Ref: Thalidomide suppresses the interleukin 1beta-induced NFkappaB signaling pathway in colon cancer cells. PMID: 12485902 Ref: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. PMID: 12507930 |
Ref: Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver(1,2). PMID: 12770647 Ref: Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. PMID: 12839942 Ref: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. PMID: 12839952 Ref: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells. PMID: 12934082 Ref: Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease. PMID: 12950415 Ref: Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling. PMID: 14506233 Ref: Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. PMID: 14520472 Ref: Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors. PMID: 14678966 |
Ref: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8]. PMID: 15034288 Ref: Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms. PMID: 15120327 Ref: Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer. PMID: 15234907 Ref: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells. PMID: 15256484 |
Ref: Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency. PMID: 15770215 Ref: Synergy between deacetylase inhibitors and IL-1beta in activation of the serum amyloid A2 gene promoter. PMID: 15812237 Ref: Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors. PMID: 15824729 Ref: Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells. PMID: 15975962 Ref: A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer. PMID: 16061869 Ref: Nuclear factor kappaB (NFkappaB) and cyclooxygenase-2 (Cox-2) expression in the irradiated colorectum is associated with subsequent histopathological changes. PMID: 16099597 Ref: Induction of apoptotic cell death by 2'-hydroxycinnamaldehyde is involved with ERK-dependent inactivation of NF-kappaB in TNF-alpha-treated SW620 colon cancer cells. PMID: 16143316 |
Ref: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. PMID: 16118352 Ref: Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. PMID: 16360644 Ref: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. PMID: 16448212 Ref: Inhibition of NF-kappaB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells. PMID: 16465375 Ref: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. PMID: 16497702 Ref: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. PMID: 16619535 Ref: Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. PMID: 16637064 Ref: Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes. PMID: 16800774 Ref: Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells. PMID: 16972245 Ref: No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemia. PMID: 17047486 |
Ref: Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis. PMID: 16777921 Ref: Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells. PMID: 17186550 Ref: Prevention of cancer cachexia by pyrrolidine dithiocarbamate (PDTC) in colon 26 tumor-bearing mice. PMID: 17202436 Ref: Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling. PMID: 17521736 Ref: CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA. PMID: 17525529 Ref: RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways. PMID: 17587138 Ref: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF. PMID: 17603079 Ref: Loss of E-cadherin in the vicinity of necrosis in colorectal carcinomas: association with NFkappaB expression. PMID: 17611682 Ref: Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. PMID: 17635998 Ref: 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. PMID: 17707368 Ref: Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations. PMID: 17852842 Ref: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. PMID: 17868752 Ref: Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway. PMID: 17938270 Ref: Sensitization of colorectal cancer cells to irradiation by IL-4 and IL-10 is associated with inhibition of NF-kappaB. PMID: 17949233 |
Ref: Cell death in response to antimetabolites directed at thymidylate synthase. PMID: 17396263 Ref: Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells. PMID: 18084005 Ref: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. PMID: 18241858 Ref: Irinotecan pharmacogenetics: influence of pharmacodynamic genes. PMID: 18347181 Ref: Increased Rac1b expression sustains colorectal tumor cell survival. PMID: 18644982 Ref: NF-kappaB-dependency and consequent regulation of IL-8 in echinomycin-induced apoptosis of HT-29 colon cancer cells. PMID: 18675368 Ref: Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis. PMID: 18694732 Ref: TNFalpha-induced activation of NFkappaB protects against UV-induced apoptosis specifically in p53-proficient cells. PMID: 19023456 Ref: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa]. PMID: 19096253 Ref: Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells. PMID: 19172851 |
Ref: Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice. PMID: 19003968 Ref: Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. PMID: 19117399 Ref: Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells. PMID: 19383900 Ref: A functional insertion/deletion polymorphism in the promoter region of the NFKB1 gene increases susceptibility for prostate cancer. PMID: 19446741 Ref: Potential mechanisms involved in ceramide-induced apoptosis in human colon cancer HT29 cells. PMID: 19462692 Ref: Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50. PMID: 19509257 Ref: Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue. PMID: 19513071 Ref: An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation. PMID: 19616541 Ref: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). PMID: 19839614 |
Ref: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells. PMID: 19243468 Ref: Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. PMID: 19782464 Ref: Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma. PMID: 20027638 Ref: Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter. PMID: 20199127 Ref: Netrin-1, a missing link between chronic inflammation and tumor progression. PMID: 20305387 Ref: Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida. PMID: 20384315 Ref: NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. PMID: 20414006 Ref: 17beta-estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells. PMID: 20446020 Ref: Colorectal carcinoma cells--regulation of survival and growth by SGK1. PMID: 20541034 Ref: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. PMID: 20653974 Ref: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism. PMID: 20730438 Ref: Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes. PMID: 20836841 Ref: Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. PMID: 21129206 Ref: Quantitative evaluation of transcriptional activation of NF-kappaB p65 and p50 subunits and IkappaBalpha encoding genes in colon cancer cells by Desulfovibrio desulfuricans endotoxin. PMID: 21253915 Ref: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells. PMID: 21713362 |
Ref: Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. PMID: 20630669 Ref: Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo. PMID: 20669245 Ref: NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). PMID: 20715105 Ref: Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action. PMID: 21406194 Ref: Antagonistic crosstalk between APC and HIF-1alpha. PMID: 21502812 Ref: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-kappaB signaling in the intestine. PMID: 21540105 Ref: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. PMID: 21544861 Ref: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity. PMID: 21586136 Ref: Extracellular Calcium-Sensing Receptor Inhibition of Intestinal EpithelialTNF Signaling Requires CaSR-Mediated Wnt5a/Ror2 Interaction. PMID: 21603229 Ref: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3. PMID: 21722370 Ref: NFkappaB1 and NFkappaBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population. PMID: 21738780 Ref: C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFkappaB in colon cancer cells and xenograft tumors. PMID: 21900746 Ref: Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to alpha5beta1 integrin and suppresses FAK/ERK/NF-kappaB signaling. PMID: 21963225 Ref: Genetic variation in inflammatory pathways is related to colorectal cancer survival. PMID: 21976545 Ref: Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells. PMID: 21994466 Ref: Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer. PMID: 22122764 |
Ref: Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells. PMID: 21678498 Ref: BAG-1 interacts with the p50-p50 homodimeric NF-kappaB complex: implications for colorectal carcinogenesis. PMID: 21963853 Ref: Colorectal cancer mouse models: integrating inflammation and the stroma. PMID: 22188027 Ref: Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. PMID: 22216762 Ref: A new model for raf kinase inhibitory protein induced chemotherapeutic resistance. PMID: 22279539 Ref: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. PMID: 22409325 Ref: Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines. PMID: 22509253 Ref: The joint association of REST and NFKB1 polymorphisms on the risk of colorectal cancer. PMID: 22530801 Ref: The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells. PMID: 22617025 Ref: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. PMID: 22992618 Ref: Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155. PMID: 23036199 Ref: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. PMID: 23110215 Ref: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. PMID: 23194063 Ref: A TLR4-interacting peptide inhibits lipopolysaccharide-stimulated inflammatory responses, migration and invasion of colon cancer SW480 cells. PMID: 23264896 |
Ref: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling. PMID: 22086675 Ref: IkappaBKbeta and NFkappaB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. PMID: 23002237 Ref: Systematic review: diet-gene interactions and the risk of colorectal cancer. PMID: 23216531 Ref: Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer. PMID: 23516545 Ref: Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFkappaB activity. PMID: 23559092 Ref: 6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor gamma (PPARgamma). PMID: 23612072 Ref: A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PMID: 23671587 Ref: Syringic acid from Tamarix aucheriana possesses antimitogenic and chemo-sensitizing activities in human colorectal cancer cells. PMID: 23745612 Ref: The functional -94 insertion/deletion ATTG polymorphism in the promoter region of NFKB1 gene increases the risk of sporadic colorectal cancer. PMID: 23806437 Ref: Chemopreventive and metabolic effects of inulin on colon cancer development. PMID: 23820222 Ref: Mechanisms involved in the antiproliferative and proapoptotic effects of unsaponifiable fraction of extra virgin olive oil on HT-29 cancer cells. PMID: 23909736 Ref: Low ABCB1 gene expression is an early event in colorectal carcinogenesis. PMID: 23977225 Ref: Acidic pH of tumor microenvironment enhances cytotoxicity of the disulfiram/Cu2+ complex to breast and colon cancer cells. PMID: 24051574 Ref: Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo. PMID: 25621077 |
Ref: Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors. PMID: 23670891 Ref: In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. PMID: 24141263 Ref: Changes chemopreventive markers in colorectal cancer development after inulin supplementation. PMID: 24601699 Ref: Prognostic value of c-FLIPL/s, HIF-1alpha, and NF-kappabeta in stage II and III rectal cancer. PMID: 24711168 Ref: Association between the NFKB1-94ins/del ATTG polymorphism and cancer risk: an updated meta-analysis. PMID: 24827594 Ref: Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms. PMID: 24847381 Ref: Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. PMID: 24959314 Ref: CYP19A1 single nucleotide polymorphism associations with CYP19A1, NFkappaB1, and IL6 gene expression in human normal colon and normal liver samples. PMID: 25114581 Ref: MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer. PMID: 25197016 Ref: Cell specific apoptosis by RLX is mediated by NFkappaB in human colon carcinoma HCT-116 cells. PMID: 25303828 Ref: Role of genetic polymorphisms in NFKB-mediated inflammatory pathways in response to primary chemoradiation therapy for rectal cancer. PMID: 25304949 Ref: Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines. PMID: 25431425 |
Ref: Interactions between meat intake and genetic variation in relation to colorectal cancer. PMID: 25491747 Ref: Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFkappaB signaling. PMID: 25704885 Ref: Polymorphisms in NFKB1 and TLR4 and interaction with dietary and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study. PMID: 25705893 Ref: NF-kappaB1, NF-kappaB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice. PMID: 25727407 Ref: Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors. PMID: 25825916 Ref: Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-kappaB activation pathway and ubiquitination. PMID: 26003312 Ref: Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells. PMID: 26030884 Ref: Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRalpha/c-SRC/ERK1/2/NFkappaB/TP53 pathway: in vitro and in vivo studies. PMID: 26056802 Ref: The different radiation response and radiation-induced bystander effects in colorectal carcinoma cells differing in p53 status. PMID: 26099456 Ref: Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression. PMID: 26123287 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: Crosstalk between the TNF and IGF pathways enhances NF-kappaB activation and signaling in cancer cells. PMID: 26239406 Ref: Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice. PMID: 26344057 Ref: Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways. PMID: 26442106 Ref: (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice. PMID: 26474284 Ref: The NF-kappaB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription. PMID: 26497740 Ref: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells. PMID: 26753095 Ref: [Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes]. PMID: 26775485 Ref: Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy. PMID: 26839513 |
Ref: Evodiamine Suppresses ABCG2 Mediated Drug Resistance by Inhibiting p50/p65 NF-kappaB Pathway in Colorectal Cancer. PMID: 26590365 Ref: RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer. PMID: 26854224 Ref: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression. PMID: 27098148 Ref: NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-kappaB pathway. PMID: 27109343 Ref: 5-Aminosalicylic Acid Azo-Linked to Procainamide Acts as an Anticolitic Mutual Prodrug via Additive Inhibition of Nuclear Factor kappaB. PMID: 27112518 Ref: [The role of inflammation in colon cancer pathogenesis]. PMID: 27117112 Ref: The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells. PMID: 27132515 Ref: DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFkappab negative regulator PPM1B. PMID: 27158335 Ref: Progesterone receptor activation is required for folic acid-induced anti-proliferation in colorectal cancer cell lines. PMID: 27233474 Ref: SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development. PMID: 27582544 Ref: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells. PMID: 27808331 |
Ref: Cytotoxic effects of the anthraquinone derivatives 1'-deoxyrhodoptilometrin and (S)-(-)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp. PMID: 27473261 Ref: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PMID: 28068431 Ref: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. PMID: 28107519 Ref: Inflammatory Molecule, PSGL-1, Deficiency Activates Macrophages to Promote Colorectal Cancer Growth through NFkappaB Signaling. PMID: 28108624 Ref: Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation. PMID: 28361920 Ref: Curcumin loading potentiates the chemotherapeutic efficacy of selenium nanoparticles in HCT116 cells and Ehrlich's ascites carcinoma bearing mice. PMID: 28499854 Ref: Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women. PMID: 28542447 Ref: Succinamide derivatives of melampomagnolide B and their anti-cancer activities. PMID: 28545815 Ref: FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells. PMID: 28591725 Ref: Sensitive and Label-Free Fluorescent Detection of Transcription Factors Based on DNA-Ag Nanoclusters Molecular Beacons and Exonuclease III-Assisted Signal Amplification. PMID: 28657304 Ref: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer. PMID: 28672935 Ref: The integrated pathway of TGFbeta/Snail with TNFalpha/NFkappaB may facilitate the tumor-stroma interaction in the EMT process and colorectal cancer prognosis. PMID: 28687755 Ref: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells. PMID: 28688953 Ref: Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells. PMID: 28706417 Ref: PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition. PMID: 28915620 Ref: Parthenolide suppresses hypoxia-inducible factor-1alpha signaling and hypoxia induced epithelial-mesenchymal transition in colorectal cancer. PMID: 29075793 Ref: Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features. PMID: 29085228 Ref: Analysis of 12 variants in the development of gastric and colorectal cancers. PMID: 29358861 |
Ref: Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation. PMID: 29069290 Ref: Chemoprevention with isothiocyanates - From bench to bedside. PMID: 29111351 Ref: Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model. PMID: 29432917 Ref: Overexpression of microRNA-15 increases the chemosensitivity of colon cancer cells to 5-fluorouracil and oxaliplatin by inhibiting the nuclear factor-kappaB signalling pathway and inducing apoptosis. PMID: 29467857 Ref: Suppression of the NFkappaB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute. PMID: 29484409 Ref: Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers. PMID: 29537081 Ref: Food Additive Sodium Benzoate (NaB) Activates NFkappaB and Induces Apoptosis in HCT116 Cells. PMID: 29565269 Ref: Meat and fiber intake and interaction with pattern recognition receptors (TLR1, TLR2, TLR4, and TLR10) in relation to colorectal cancer in a Danish prospective, case-cohort study. PMID: 29566186 Ref: Protumor Steering of Cancer Inflammation by p50 NF-kappaB Enhances Colorectal Cancer Progression. PMID: 29588321 Ref: betaarrestin2 promotes 5FUinduced apoptosis via the NFkappaB pathway in colorectal cancer. PMID: 29620228 Ref: A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis. PMID: 30012671 Ref: Pin2/TRF1binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factorkappaB signaling pathway. PMID: 30015978 Ref: Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer. PMID: 30038258 Ref: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer. PMID: 30058122 Ref: Upregulation of PDL1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300mediated NFkappaB signaling. PMID: 30066852 Ref: ZBTB7 evokes 5-fluorouracil resistance in colorectal cancer through the NFkappaB signaling pathway. PMID: 30106136 Ref: miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. PMID: 30171794 Ref: Molecular targeting of breast and colon cancer cells by PAR1 mediated apoptosis through a novel pro-apoptotic peptide. PMID: 30196356 Ref: Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A. PMID: 30251681 Ref: Incremental Elevations in TNFalpha and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity. PMID: 30291114 Ref: Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line. PMID: 30314650 Ref: CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFkappaB and/or caspase-3/7 signaling pathway. PMID: 30344756 Ref: Metformin inhibited colitis and colitis-associated cancer (CAC) through protecting mitochondrial structures of colorectal epithelial cells in mice. PMID: 30359174 |