Primary Site >> Colorectal Cancer

Gene >> NF1

Journal: J Clin Invest. 1991 May;87(5):1691-9.
Title: Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.
Author: Khosla, S|Patel, V M|Hay, I D|Schaid, D J|Grant, C S|van Heerden, J A|Thibodeau, S N
PMID: 2022740
Journal: Environ Health Perspect. 1992 Nov;98:25-37.
Title: Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers.
Author: Evans, H J|Prosser, J
PMID: 1336726
Journal: Gan To Kagaku Ryoho. 1992 Jan;19(1):1-7.
Title: [Positional cloning of genes responsible for hereditary tumors].
Author: Yamakawa, K|Nakamura, Y
PMID: 1346083
Journal: Br J Cancer. 1994 Nov;70(5):813-8.
Title: Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction.
Author: Cawkwell, L|Lewis, F A|Quirke, P
PMID: 7947085
Journal: Curr Opin Oncol. 1994 Mar;6(2):212-20.
Title: Cytokines, growth factors and the loss of negative growth controls in the progression of human cutaneous malignant melanoma.
Author: Lu, C|Kerbel, R S
PMID: 8011699
Journal: Oncogene. 1994 Oct;9(10):2905-12.
Title: Isolation and characterization of the promoter region of human nm23-H1, a metastasis suppressor gene.
Author: Chen, H C|Wang, L|Banerjee, S
PMID: 8084595
Journal: Med Pediatr Oncol. 1994;22(2):78-83.
Title: Neurofibromatosis type I and malignancy: review of 32 pediatric cases treated at a single institution.
Author: Shearer, P|Parham, D|Kovnar, E|Kun, L|Rao, B|Lobe, T|Pratt, C
PMID: 8259105
Journal: Environ Health Perspect. 1994 Jan;102(1):58-9.
Title: Ethical, legal, and social issues of the Human Genome Project: what to do with what we know.
Author: Pellerin, C
PMID: 9719668
Journal: Br J Cancer. 1995 May;71(5):1070-3.
Title: Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.
Author: Leggett, B|Young, J|Buttenshaw, R|Thomas, L|Young, B|Chenevix-Trench, G|Searle, J|Ward, M
PMID: 7734302
Journal: Cancer Res. 1996 Jun 15;56(12):2872-6.
Title: Suppression of a human colon cancer cell line by introduction of an exogenous NF1 gene.
Author: Li, Y|White, R
PMID: 8665528
Journal: Anticancer Res. 1997 Nov-Dec;17(6D):4515-7.
Title: Debrisoquine hydroxylase gene polymorphism in neurofibromatosis type 1.
Author: Wundrack, I|Sasiadek, M|Blin, N
PMID: 9494560
Journal: Leuk Res. 1998 Nov;22(11):1003-7.
Title: Mutational analysis of N-RAS and GAP-related domain of the neurofibromatosis type 1 gene in chronic myelogenous leukemia.
Author: Garicochea, B|Giorgi, R|Odone, V F|Dorlhiac-Llacer, P E|Bendit, I
PMID: 9783802
Journal: Bull Cancer. 1999 Oct;86(10):812-4.
Title: [HNPCC syndrome, microsatellite instability and NF1 gene alteration].
Author: Puisieux, A
PMID: 10572231
Journal: Hautarzt. 1999 Jun;50(6):398-405.
Title: [Pathogenesis of malignant melanoma. Molecular biology aspect].
Author: Waldmann, V|Bock, M|Jackel, A|Deichmann, M|Dockendorff, K|Naher, H
PMID: 10427507
Journal: J Pathol. 1999 Mar;187(4):433-8.
Title: Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.
Author: Al-Mulla, F|Milner-White, E J|Going, J J|Birnie, G D
PMID: 10398103
Journal: Cancer Res. 2002 Jan 15;62(2):359-62.
Title: A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple cafe-au-lait spots.
Author: Whiteside, Darcy|McLeod, Ross|Graham, Gail|Steckley, Jamie L|Booth, Karen|Somerville, Martin J|Andrew, Susan E
PMID: 11809679
Journal: Gynecol Oncol. 2002 Sep;86(3):375-8.
Title: BRCA1-related malignancies in a family presenting with von Recklinghausen's disease.
Author: Ceccaroni, Marcello|Genuardi, Maurizio|Legge, Francesco|Lucci-Cordisco, Emanuela|Carrara, Stefania|D'Amico, Franca|Greggi, Stefano|Scambia, Giovanni
PMID: 12217765
Journal: Nat Biotechnol. 2003 Feb;21(2):194-7. Epub 2003 Jan 13.
Title: A high-throughput nonisotopic protein truncation test.
Author: Gite, Sadanand|Lim, Mark|Carlson, Rick|Olejnik, Jerzy|Zehnbauer, Barbara|Rothschild, Kenneth
PMID: 12524552
Journal: Fam Cancer. 2004;3(2):123-7.
Title: A homozygous MSH6 mutation in a child with cafe-au-lait spots, oligodendroglioma and rectal cancer.
Author: Menko, Fred H|Kaspers, Gertjan L|Meijer, Gerrit A|Claes, Kathleen|van Hagen, Johanna M|Gille, Johan J P
PMID: 15340263
Journal: Hum Pathol. 2004 Sep;35(9):1105-11.
Title: Loss of heterozygosity reveals non-VHL allelic loss in hemangioblastomas at 22q13.
Author: Beckner, Marie E|Sasatomi, Eizaburo|Swalsky, Patricia A|Hamilton, Ronald L|Pollack, Ian F|Finkelstein, Sydney D
PMID: 15343513
Journal: Pediatr Blood Cancer. 2005 Apr;44(4):427-8.
Title: Neurofibromatosis type 1 and hereditary non-polyposis colorectal cancer: is there a link?
Author: Barbaric, Draga|Stevens, Michael|Dalla-Pozza, Luciano
PMID: 15468301
Journal: Am J Gastroenterol. 2005 Feb;100(2):476-90.
Title: The hamartomatous polyposis syndromes: a clinical and molecular review.
Author: Schreibman, Ian Roy|Baker, Maria|Amos, Christopher|McGarrity, Thomas J
PMID: 15667510
Journal: Gut. 2005 Aug;54(8):1129-35.
Title: NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer.
Author: Cacev, T|Radosevic, S|Spaventi, R|Pavelic, K|Kapitanovic, S
PMID: 15840687
Journal: Mol Cancer Res. 2005 May;3(5):251-60.
Title: Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome.
Author: Offman, Judith|Gascoigne, Karen|Bristow, Fiona|Macpherson, Peter|Bignami, Margherita|Casorelli, Ida|Leone, Giuseppe|Pagano, Livio|Sica, Simona|Halil, Ozay|Cummins, David|Banner, Nicholas R|Karran, Peter
PMID: 15886296
Journal: Clin Cancer Res. 2005 Jul 1;11(13):4689-93.
Title: A homozygous mutation in MSH6 causes Turcot syndrome.
Author: Hegde, Madhuri R|Chong, Belinda|Blazo, Maria E|Chin, Lip Hon E|Ward, Patricia A|Chintagumpala, Murali M|Kim, John Y|Plon, Sharon E|Richards, C Sue
PMID: 16000562
Journal: Fam Cancer. 2005;4(4):323-33.
Title: Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations.
Author: Bandipalliam, Prathap
PMID: 16341812
Journal: Eur J Hum Genet. 2006 May;14(5):561-6.
Title: Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor.
Author: Plaschke, Jens|Linnebacher, Michael|Kloor, Matthias|Gebert, Johannes|Cremer, Friedrich W|Tinschert, Sigrid|Aust, Daniela E|von Knebel Doeberitz, Magnus|Schackert, Hans K
PMID: 16418736
Journal: Fam Cancer. 2006;5(1):29-34.
Title: Mutational targets in colorectal cancer cells with microsatellite instability.
Author: Bertholon, Jacques|Wang, Qing|Galmarini, Carlos Maria|Puisieux, Alain
PMID: 16528606
Journal: Cancer Genet Cytogenet. 2006 Mar;165(2):98-105.
Title: Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: a study of 10 tumors from nine patients.
Author: Kobayashi, Chikashi|Oda, Yoshinao|Takahira, Tomonari|Izumi, Teiyu|Kawaguchi, Kenichi|Yamamoto, Hidetaka|Tamiya, Sadafumi|Yamada, Tomomi|Oda, Shinya|Tanaka, Kazuhiro|Matsuda, Shuichi|Iwamoto, Yukihide|Tsuneyoshi, Masazumi
PMID: 16527603
Journal: J Pediatr Surg. 2006 Feb;41(2):e19-22.
Title: Malignant peripheral nerve sheath tumor arising from the colon in a newborn: report of a case and review of the literatures.
Author: Lee, Young-Joon|Moon, HyeongGon|Park, Soon-Tae|Ha, Woo-Song|Choi, Sang-Gyeong|Hong, Soon-Chan|Joo, Young-Tae|Jeong, Chi-Young|Jung, Eun-Jung
PMID: 16481232
Journal: J Natl Cancer Inst. 2006 Mar 1;98(5):358-61.
Title: PMS2 mutations in childhood cancer.
Author: De Vos, Michel|Hayward, Bruce E|Charlton, Ruth|Taylor, Graham R|Glaser, Adam W|Picton, Susan|Cole, Trevor R|Maher, Eamonn R|McKeown, Carole M E|Mann, Jill R|Yates, John R|Baralle, Diana|Rankin, Julia|Bonthron, David T|Sheridan, Eamonn
PMID: 16507833
Journal: Eur J Hum Genet. 2008 Jan;16(1):62-72. Epub 2007 Sep 12.
Title: Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1.
Author: Kruger, Stefan|Kinzel, Miriam|Walldorf, Constanze|Gottschling, Sven|Bier, Andrea|Tinschert, Sigrid|von Stackelberg, Arend|Henn, Wolfram|Gorgens, Heike|Boue, Stephanie|Kolble, Konrad|Buttner, Reinhard|Schackert, Hans K
PMID: 17851451
Journal: Neoplasia. 2008 Jul;10(7):680-6, 2 p following 686.
Title: RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A.
Author: Ahlquist, Terje|Bottillo, Irene|Danielsen, Stine A|Meling, Gunn I|Rognum, Torleiv O|Lind, Guro E|Dallapiccola, Bruno|Lothe, Ragnhild A
PMID: 18592002
Journal: Hum Genet. 2008 Sep;124(2):105-22.
Title: Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?
Author: Wimmer, Katharina|Etzler, Julia
PMID: 18709565
Journal: Fam Cancer. 2009;8(3):187-94.
Title: Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I.
Author: Toledano, Helen|Goldberg, Yael|Kedar-Barnes, Inbal|Baris, Hagit|Porat, Rinnat M|Shochat, Chen|Bercovich, Dani|Pikarsky, Eli|Lerer, Israela|Yaniv, Isaac|Abeliovich, Dvorah|Peretz, Tamar
PMID: 19101824
Journal: Int J Colorectal Dis. 2009 Aug;24(8):865-74.
Title: Genetics of the hamartomatous polyposis syndromes: a molecular review.
Author: Chen, Hui-Min|Fang, Jing-Yuan
PMID: 19381654
Journal: J Korean Soc Coloproctol. 2012 Jun;28(3):170-3.
Title: A case of rectal cancer in a patient with neurofibromatosis type 1.
Author: Oh, Se Heon|Lee, Jai Hyuen|Namgung, Hwan
PMID: 22816062
Journal: PLoS One. 2014 Jan 27;9(1):e82185.
Title: An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Author: Brim, Hassan|Abu-Asab, Mones S|Nouraie, Mehdi|Salazar, Jose|Deleo, Jim|Razjouyan, Hadi|Mokarram, Pooneh|Schaffer, Alejandro A|Naghibhossaini, Fakhraddin|Ashktorab, Hassan
PMID: 24475022
Journal: Ann Surg Treat Res. 2014 Sep;87(3):156-60.
Title: Synchronous multiple colonic adenocarcinomas arising in patient with neurofibromatosis type 1.
Author: Kim, Ik Yong|Cho, Mee Yon|Kim, Young Wan
PMID: 25247170
Journal: Indian J Hum Genet. 2014 Apr;20(2):192-4.
Title: Constitutional mismatch repair deficiency syndrome: Do we know it?
Author: Ramachandra, C|Challa, Vasu Reddy|Shetty, Rachan
PMID: 25400351
Journal: Mol Cancer Ther. 2015 Dec;14(12):2700-11.
Title: Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors.
Author: Whittaker, Steven R|Cowley, Glenn S|Wagner, Steve|Luo, Flora|Root, David E|Garraway, Levi A
PMID: 26351322
Journal: Cancer Genet. 2016 Apr;209(4):119-29.
Title: Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors.
Author: Mukherjee, S|Ma, Z|Wheeler, S|Sathanoori, M|Coldren, C|Prescott, J L|Kozyr, N|Bouzyk, M|Correll, M|Ho, H|Chandra, P K|Lennon, P A
PMID: 26880400
Journal: Anticancer Res. 2016 Oct;36(10):5301-5306.
Title: Neurofibromin Expression is Associated with Aggressive Disease and Poor Outcome in Colorectal Carcinoma.
Author: Elzagheid, Adam|Emaetig, Fatma|Elsaghayer, Wesam|Torjman, Fairouz|Latto, Matti|Syrjanen, Kari|Collan, Yrjo|Pyrhonen, Seppo
PMID: 27798892
Journal: Adv Med Biol. 2017 1st Quarter;118:83-122.
Title: Haploinsufficient tumor suppressor genes.
Author: Inoue, Kazushi|Fry, Elizabeth A
PMID: 28680740
Journal: World J Surg Oncol. 2017 Aug 23;15(1):160.
Title: Rectal carcinoma and multiple gastrointestinal stromal tumors (GIST) of the small intestine in a patient with neurofibromatosis type 1: a case report.
Author: Hakozaki, Yuhei|Sameshima, Shinichi|Tatsuoka, Teppei|Okuyama, Takashi|Yamagata, Yukinori|Noie, Tamaki|Oya, Masatoshi|Fujii, Akiko|Ueda, Yoshihiko|Shimura, Chieko|Katagiri, Kazumoto
PMID: 28835241
Journal: Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title: Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author: Hou, Helei|Liu, Dong|Zhang, Chuantao|Jiang, Yanxia|Lu, Guifang|Zhou, Na|Yang, Xiaonan|Zhang, Xiaoping|Li, Zhuokun|Zhu, Hongmei|Qian, Zhaoyang|Zhang, Xiaochun
PMID: 29285234
Journal: Cancer. 2018 Mar 1;124(5):1070-1082.
Title: A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.
Author: Tricoli, James V|Boardman, Lisa A|Patidar, Rajesh|Sindiri, Sivasish|Jang, Jin S|Walsh, William D|McGregor, Paul M 3rd|Camalier, Corinne E|Mehaffey, Michele G|Furman, Wayne L|Bahrami, Armita|Williams, P Mickey|Lih, Chih-Jian|Conley, Barbara A|Khan, Javed
PMID: 29194591
Journal: Int J Cancer. 2018 Jul 15;143(2):289-297.
Title: DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1/NF1 switch axis on genomic locus.
Author: Wu, Shenshen|Meng, Qingtao|Zhang, Chengcheng|Sun, Hao|Lu, Runze|Gao, Na|Yang, Hongbao|Li, Xiaobo|Aschner, Michael|Chen, Rui
PMID: 29446085
Journal: Anticancer Res. 2018 Apr;38(4):2235-2240.
Title: Racial Disparities in the Molecular Landscape of Cancer.
Author: Heath, Elisabeth I|Lynce, Filipa|Xiu, Joanne|Ellerbrock, Angela|Reddy, Sandeep K|Obeid, Elias|Liu, Stephen V|Bollig-Fischer, Aliccia|Separovic, Duska|Vanderwalde, Ari
PMID: 29599344
Journal: J Pathol. 2018 Oct;246(2):166-179.
Title: Circular RNA circITGA7 inhibits colorectal cancer growth and metastasis by modulating the Ras pathway and upregulating transcription of its host gene ITGA7.
Author: Li, Xiaomin|Wang, Jianjun|Zhang, Chao|Lin, Chun|Zhang, Jianming|Zhang, Wei|Zhang, Wenjuan|Lu, Yanxia|Zheng, Lin|Li, Xuenong
PMID: 29943828
Journal: Oncologist. 2018 Jul 17. pii: theoncologist.2018-0117.
Title: Impact of Patient Age on Molecular Alterations of Left-Sided Colorectal Tumors.
Author: Puccini, Alberto|Lenz, Heinz-Josef|Marshall, John L|Arguello, David|Raghavan, Derek|Korn, W Michael|Weinberg, Benjamin A|Poorman, Kelsey|Heeke, Arielle L|Philip, Philip A|Shields, Anthony F|Goldberg, Richard M|Salem, Mohamed E
PMID: 30018131
Journal: Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title: Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author: Domingo, Enric|Camps, Carme|Kaisaki, Pamela J|Parsons, Marie J|Mouradov, Dmitri|Pentony, Melissa M|Makino, Seiko|Palmieri, Michelle|Ward, Robyn L|Hawkins, Nicholas J|Gibbs, Peter|Askautrud, Hanne|Oukrif, Dahmane|Wang, Haitao|Wood, Joe|Tomlinson, Evie|Bark
PMID: 30042065
Journal: Nat Commun. 2018 Aug 9;9(1):3166.
Title: Identification of nine new susceptibility loci for endometrial cancer.
Author: O'Mara, Tracy A|Glubb, Dylan M|Amant, Frederic|Annibali, Daniela|Ashton, Katie|Attia, John|Auer, Paul L|Beckmann, Matthias W|Black, Amanda|Bolla, Manjeet K|Brauch, Hiltrud|Brenner, Hermann|Brinton, Louise|Buchanan, Daniel D|Burwinkel, Barbara|Chang-Claude
PMID: 30093612