Primary Site >> Colorectal Cancer
Gene >> NF1
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Ref: Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas. PMID: 2022740 |
Ref: Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers. PMID: 1336726 Ref: [Positional cloning of genes responsible for hereditary tumors]. PMID: 1346083 |
Ref: Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. PMID: 7947085 Ref: Cytokines, growth factors and the loss of negative growth controls in the progression of human cutaneous malignant melanoma. PMID: 8011699 Ref: Isolation and characterization of the promoter region of human nm23-H1, a metastasis suppressor gene. PMID: 8084595 Ref: Neurofibromatosis type I and malignancy: review of 32 pediatric cases treated at a single institution. PMID: 8259105 Ref: Ethical, legal, and social issues of the Human Genome Project: what to do with what we know. PMID: 9719668 |
Ref: Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region. PMID: 7734302 |
Ref: Suppression of a human colon cancer cell line by introduction of an exogenous NF1 gene. PMID: 8665528 |
Ref: Debrisoquine hydroxylase gene polymorphism in neurofibromatosis type 1. PMID: 9494560 |
Ref: Mutational analysis of N-RAS and GAP-related domain of the neurofibromatosis type 1 gene in chronic myelogenous leukemia. PMID: 9783802 |
Ref: Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression. PMID: 10398103 Ref: [Pathogenesis of malignant melanoma. Molecular biology aspect]. PMID: 10427507 Ref: [HNPCC syndrome, microsatellite instability and NF1 gene alteration]. PMID: 10572231 |
Ref: A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple cafe-au-lait spots. PMID: 11809679 Ref: BRCA1-related malignancies in a family presenting with von Recklinghausen's disease. PMID: 12217765 |
Ref: A high-throughput nonisotopic protein truncation test. PMID: 12524552 |
Ref: A homozygous MSH6 mutation in a child with cafe-au-lait spots, oligodendroglioma and rectal cancer. PMID: 15340263 Ref: Loss of heterozygosity reveals non-VHL allelic loss in hemangioblastomas at 22q13. PMID: 15343513 |
Ref: Neurofibromatosis type 1 and hereditary non-polyposis colorectal cancer: is there a link? PMID: 15468301 Ref: The hamartomatous polyposis syndromes: a clinical and molecular review. PMID: 15667510 Ref: NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer. PMID: 15840687 Ref: Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome. PMID: 15886296 Ref: A homozygous mutation in MSH6 causes Turcot syndrome. PMID: 16000562 Ref: Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations. PMID: 16341812 |
Ref: Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor. PMID: 16418736 Ref: Malignant peripheral nerve sheath tumor arising from the colon in a newborn: report of a case and review of the literatures. PMID: 16481232 Ref: PMS2 mutations in childhood cancer. PMID: 16507833 Ref: Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: a study of 10 tumors from nine patients. PMID: 16527603 Ref: Mutational targets in colorectal cancer cells with microsatellite instability. PMID: 16528606 |
Ref: Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1. PMID: 17851451 Ref: RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A. PMID: 18592002 Ref: Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg? PMID: 18709565 |
Ref: Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I. PMID: 19101824 Ref: Genetics of the hamartomatous polyposis syndromes: a molecular review. PMID: 19381654 |
Ref: A case of rectal cancer in a patient with neurofibromatosis type 1. PMID: 22816062 |
Ref: An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors. PMID: 24475022 Ref: Synchronous multiple colonic adenocarcinomas arising in patient with neurofibromatosis type 1. PMID: 25247170 Ref: Constitutional mismatch repair deficiency syndrome: Do we know it? PMID: 25400351 |
Ref: Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors. PMID: 26351322 |
Ref: Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors. PMID: 26880400 Ref: Neurofibromin Expression is Associated with Aggressive Disease and Poor Outcome in Colorectal Carcinoma. PMID: 27798892 |
Ref: Haploinsufficient tumor suppressor genes. PMID: 28680740 Ref: Rectal carcinoma and multiple gastrointestinal stromal tumors (GIST) of the small intestine in a patient with neurofibromatosis type 1: a case report. PMID: 28835241 Ref: Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine. PMID: 29285234 |
Ref: A mutational comparison of adult and adolescent and young adult (AYA) colon cancer. PMID: 29194591 Ref: DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1/NF1 switch axis on genomic locus. PMID: 29446085 Ref: Racial Disparities in the Molecular Landscape of Cancer. PMID: 29599344 Ref: Circular RNA circITGA7 inhibits colorectal cancer growth and metastasis by modulating the Ras pathway and upregulating transcription of its host gene ITGA7. PMID: 29943828 Ref: Impact of Patient Age on Molecular Alterations of Left-Sided Colorectal Tumors. PMID: 30018131 Ref: Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series. PMID: 30042065 Ref: Identification of nine new susceptibility loci for endometrial cancer. PMID: 30093612 |