Primary Site >> Colorectal Cancer

Gene >> NEK2

Journal: Cancer Sci. 2010 May;101(5):1163-9.
Title: Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin.
Author: Suzuki, Kazushi|Kokuryo, Toshio|Senga, Takeshi|Yokoyama, Yukihiro|Nagino, Masato|Hamaguchi, Michinari
PMID: 20345485
Journal: Exp Mol Pathol. 2012 Feb;92(1):27-32.
Title: Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.
Author: Mori, Takashi|Nishizawa, Satoshi|Hirohashi, Yoshihiko|Torigoe, Toshihiko|Tamura, Yasuaki|Takahashi, Akari|Kochin, Vitaly|Fujii, Reona|Kondo, Toru|Greene, Mark I|Hara, Isao|Sato, Noriyuki
PMID: 22001602
Journal: J Biol Chem. 2013 Dec 13;288(50):35940-51.
Title: Local depletion of DNA methylation identifies a repressive p53 regulatory region in the NEK2 promoter.
Author: Nabilsi, Nancy H|Ryder, Daniel J|Peraza-Penton, Ashley C|Poudyal, Rosha|Loose, David S|Kladde, Michael P
PMID: 24163369
Journal: Ann Surg Oncol. 2014 Jan;21(1):205-12.
Title: Up-regulation of NEK2 by microRNA-128 methylation is associated with poor prognosis in colorectal cancer.
Author: Takahashi, Yusuke|Iwaya, Takeshi|Sawada, Genta|Kurashige, Junji|Matsumura, Tae|Uchi, Ryutaro|Ueo, Hiroki|Takano, Yuki|Eguchi, Hidetoshi|Sudo, Tomoya|Sugimachi, Keishi|Yamamoto, Hirofumi|Doki, Yuichiro|Mori, Masaki|Mimori, Koshi
PMID: 24046120
Journal: J Exp Clin Cancer Res. 2014 Jan 9;33:6.
Title: Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1.
Author: Huang, Lynn Y L|Lee, Ying-Shuan|Huang, Jiann-Jyh|Chang, Chia-chi|Chang, Jia-Ming|Chuang, Shih-Hsien|Kao, Kuo-Jang|Tsai, Yung-Jen|Tsai, Pei-Yi|Liu, Chia-Wei|Lin, Her-Sheng|Lau, Johnson Y N
PMID: 24401611
Journal: J Surg Oncol. 2014 Dec;110(7):828-38.
Title: Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.
Author: Neal, Christopher P|Fry, Andrew M|Moreman, Catherine|McGregor, Angus|Garcea, Giuseppe|Berry, David P|Manson, Margaret M
PMID: 25043295
Journal: Int J Clin Exp Pathol. 2015 Nov 1;8(11):15467-73. eCollection 2015.
Title: Clinical significance and prognostic value of Nek2 protein expression in colon cancer.
Author: Lu, Lei|Zhai, Xiaofeng|Yuan, Ronghua
PMID: 26823916
Journal: J Gastroenterol Hepatol. 2016 Jan;31(1):256-64.
Title: Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Author: Wubetu, Gizachew Y|Shimada, Mitsuo|Morine, Yuji|Ikemoto, Tetsuya|Ishikawa, Daichi|Iwahashi, Shuichi|Yamada, Shinichiro|Saito, Yu|Arakawa, Yusuke|Imura, Satoru
PMID: 26241688
Journal: Cancer Sci. 2016 Sep;107(9):1315-20.
Title: Nek2 siRNA therapy using a portal venous port-catheter system for liver metastasis in pancreatic cancer.
Author: Kokuryo, Toshio|Hibino, Shigeru|Suzuki, Kazushi|Watanabe, Katsutaka|Yokoyama, Yukihiro|Nagino, Masato|Senga, Takeshi|Hamaguchi, Michinari
PMID: 27316377
Journal: Oncotarget. 2016 Nov 29;7(48):79327-79341.
Title: Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity.
Author: Fang, Yanfen|Kong, Yannan|Xi, Jianbei|Zhu, Mengli|Zhu, Tong|Jiang, Tongtong|Hu, Wenhao|Ma, Mingliang|Zhang, Xiongwen
PMID: 27764815
Journal: Thorac Cancer. 2017 Jul;8(4):304-311.
Title: MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2.
Author: Zhao, Dejian|Han, Wenzheng|Liu, Xia|Cui, Dawei|Chen, Yu
PMID: 28514100