Primary Site >> Colorectal Cancer

Gene >> NEK2

  • 2010
  • 2012
  • 2013
  • 2014
  • 2015
  • 2016
  • 2017
Ref: Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin.
PMID: 20345485
Ref: Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.
PMID: 22001602
Ref: Local depletion of DNA methylation identifies a repressive p53 regulatory region in the NEK2 promoter.
PMID: 24163369
Ref: Up-regulation of NEK2 by microRNA-128 methylation is associated with poor prognosis in colorectal cancer.
PMID: 24046120
Ref: Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1.
PMID: 24401611
Ref: Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.
PMID: 25043295
Ref: Clinical significance and prognostic value of Nek2 protein expression in colon cancer.
PMID: 26823916
Ref: Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
PMID: 26241688
Ref: Nek2 siRNA therapy using a portal venous port-catheter system for liver metastasis in pancreatic cancer.
PMID: 27316377
Ref: Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity.
PMID: 27764815
Ref: MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2.
PMID: 28514100