Primary Site >> Colorectal Cancer
Gene >> NEDD8
| 1. | |||||||||||
| Journal: | Hepatology. 2012 Apr;55(4):1237-48. | ||||||||||
| Title: | Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation. | ||||||||||
| Author: | Embade, Nieves|Fernandez-Ramos, David|Varela-Rey, Marta|Beraza, Naiara|Sini, Marcella|Gutierrez de Juan, Virginia|Woodhoo, Ashwin|Martinez-Lopez, Nuria|Rodriguez-Iruretagoyena, Begona|Bustamante, Francisco Javier|de la Hoz, Ana Belen|Carracedo, Arkaitz|Xi | ||||||||||
| PMID: | 22095636 | ||||||||||
| 2. | |||||||||||
| Journal: | Cell Rep. 2012 Apr 19;1(4):309-16. | ||||||||||
| Title: | A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924. | ||||||||||
| Author: | Toth, Julia I|Yang, Li|Dahl, Russell|Petroski, Matthew D | ||||||||||
| PMID: | 22832224 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2013 Jan 1;73(1):225-34. | ||||||||||
| Title: | Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924. | ||||||||||
| Author: | Blank, Jonathan L|Liu, Xiaozhen J|Cosmopoulos, Katherine|Bouck, David C|Garcia, Khristofer|Bernard, Hugues|Tayber, Olga|Hather, Greg|Liu, Ray|Narayanan, Usha|Milhollen, Michael A|Lightcap, Eric S | ||||||||||
| PMID: | 23100467 | ||||||||||
| 4. | |||||||||||
| Journal: | Nat Commun. 2014 May 13;5:3733. | ||||||||||
| Title: | The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis. | ||||||||||
| Author: | Xie, Ping|Zhang, Minghua|He, Shan|Lu, Kefeng|Chen, Yuhan|Xing, Guichun|Lu, Yiming|Liu, Ping|Li, Yang|Wang, Shaoxia|Chai, Nan|Wu, Jiawei|Deng, Haiteng|Wang, Hong-Rui|Cao, Yu|Zhao, Fei|Cui, Yu|Wang, Jian|He, Fuchu|Zhang, Lingqiang | ||||||||||
| PMID: | 24821572 | ||||||||||
| 5. | |||||||||||
| Journal: | Am J Cancer Res. 2015 Oct 15;5(11):3400-6. eCollection 2015. | ||||||||||
| Title: | Molecular dynamics simulation on the low sensitivity of mutants of NEDD-8 activating enzyme for MLN4924 inhibitor as a cancer drug. | ||||||||||
| Author: | Rashidieh, Behnam|Valizadeh, Mohharam|Assadollahi, Vahideh|Ranjbar, Mohammad Mehdi | ||||||||||
| PMID: | 26807320 | ||||||||||
| 6. | |||||||||||
| Journal: | Technol Cancer Res Treat. 2016 Aug;15(4):527-34. | ||||||||||
| Title: | Radiosensitization of Human Colorectal Cancer Cells by MLN4924: An Inhibitor of NEDD8-Activating Enzyme. | ||||||||||
| Author: | Wan, Juefeng|Zhu, Ji|Li, Guichao|Zhang, Zhen | ||||||||||
| PMID: | 26082455 | ||||||||||
| 7. | |||||||||||
| Journal: | J Natl Cancer Inst. 2016 Oct 22;109(2). pii: djw209. | ||||||||||
| Title: | Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer. | ||||||||||
| Author: | Picco, Gabriele|Petti, Consalvo|Sassi, Francesco|Grillone, Katia|Migliardi, Giorgia|Rossi, Teresa|Isella, Claudio|Di Nicolantonio, Federica|Sarotto, Ivana|Sapino, Anna|Bardelli, Alberto|Trusolino, Livio|Bertotti, Andrea|Medico, Enzo | ||||||||||
| PMID: | 27771609 | ||||||||||
| 8. | |||||||||||
| Journal: | Eur J Med Chem. 2017 Jun 16;133:174-183. | ||||||||||
| Title: | Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening. | ||||||||||
| Author: | Ma, Hao|Zhuang, Chunlin|Xu, Xiguo|Li, Jiao|Wang, Juan|Min, Xiao|Zhang, Wannian|Zhang, Huojun|Miao, Zhenyuan | ||||||||||
| PMID: | 28388520 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Med Rep. 2017 May;15(5):2795-2801. | ||||||||||
| Title: | Neural precursor cell expressed, developmentally downregulated 8activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis. | ||||||||||
| Author: | Zheng, Wanwei|Luo, Zhongguang|Zhang, Jun|Min, Pei|Li, Wenshuai|Xu, Diannan|Zhang, Ziqiang|Xiong, Panpan|Liang, Hong|Liu, Jie | ||||||||||
| PMID: | 28447739 | ||||||||||
| 10. | |||||||||||
| Journal: | Anticancer Drugs. 2018 Oct;29(9):854-860. | ||||||||||
| Title: | Construction and characterization of regulated cycle inhibiting factors induced upon Tet-On system in human colon cancer cell lines. | ||||||||||
| Author: | Liu, Liang|Ni, Jianjiao|Zhang, Junhua|He, Xinhong | ||||||||||
| PMID: | 29923895 | ||||||||||