Primary Site >> Colorectal Cancer

Gene >> NDRG2

Journal: BMC Cancer. 2007 Oct 12;7:192.
Title: Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma.
Author: Lorentzen, Anders|Vogel, Lotte K|Lewinsky, Rikke H|Saebo, Mona|Skjelbred, Camilla F|Godiksen, Sine|Hoff, Geir|Tveit, Kjell M|Lothe, Inger Marie Bowitz|Ikdahl, Tone|Kure, Elin H|Mitchelmore, Cathy
PMID: 17935612
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Jul;11(4):354-7.
Title: [Expression of candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colon cancer].
Author: Chu, Da-Ke|Zhang, Jian|Shi, Hai|Dong, Guang-Long|Liu, Xin-Pin|Wang, Wei-Zhong
PMID: 18636358
Journal: Int J Cancer. 2009 Jan 1;124(1):7-15.
Title: NDRG2 suppresses cell proliferation through down-regulation of AP-1 activity in human colon carcinoma cells.
Author: Kim, Young Jun|Yoon, Sun Young|Kim, Jong-Tae|Choi, Seung Cheol|Lim, Jong-Seok|Kim, Joo Heon|Song, Eun Young|Lee, Hee Gu|Choi, Inpyoi|Kim, Jae Wha
PMID: 18844221
Journal: Carcinogenesis. 2009 Apr;30(4):598-605.
Title: NDRG2 expression decreases with tumor stages and regulates TCF/beta-catenin signaling in human colon carcinoma.
Author: Kim, Young-Jun|Yoon, Sun Y|Kim, Jong-Tae|Song, Eun Y|Lee, Hee G|Son, Hyun J|Kim, Soo Y|Cho, Daeho|Choi, Inpyo|Kim, Joo H|Kim, Jae W
PMID: 19237607
Journal: BMC Med Genomics. 2009 Mar 3;2:11.
Title: Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour.
Author: Piepoli, Ada|Cotugno, Rosa|Merla, Giuseppe|Gentile, Annamaria|Augello, Bartolomeo|Quitadamo, Michele|Merla, Antonio|Panza, Anna|Carella, Massimo|Maglietta, Rosalia|D'Addabbo, Annarita|Ancona, Nicola|Fusilli, Saverio|Perri, Francesco|Andriulli, Angelo
PMID: 19257893
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 May;12(3):281-4.
Title: [Expression and significance of new candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colorectal cancer].
Author: Shi, Hai|Wang, Wei-Zhong|Yao, Li-Bo|Zhang, Jian|Yin, Qin|Xu, Chun-Sheng|Chu, Da-Ke|Dong, Guang-Long|Zhang, Hong-Wei|Li, Ji-Peng
PMID: 19434539
Journal: Biol Pharm Bull. 2009 Jun;32(6):968-75.
Title: Suppression of N-myc downstream-regulated gene 2 is associated with induction of Myc in colorectal cancer and correlates closely with differentiation.
Author: Shi, Hai|Jin, Haifeng|Chu, Dake|Wang, Weizhong|Zhang, Jian|Chen, Changsheng|Xu, Chunsheng|Fan, Daiming|Yao, Libo
PMID: 19483300
Journal: Mol Cancer Ther. 2011 Jan;10(1):47-56.
Title: Prediction of colorectal cancer relapse and prognosis by tissue mRNA levels of NDRG2.
Author: Chu, Dake|Zhang, Zixi|Li, Yunming|Wu, Lin|Zhang, Jing|Wang, Weizhong|Zhang, Jian
PMID: 21220491
Journal: J Biol Chem. 2011 Apr 8;286(14):12450-60.
Title: Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
Author: Hwang, Jungwon|Kim, Yoonjeong|Kang, Ho Bum|Jaroszewski, Lukasz|Deacon, Ashley M|Lee, Hwiseop|Choi, Won-Chan|Kim, Kyung-Jin|Kim, Cheol-Hee|Kang, Beom Sik|Lee, Jie-Oh|Oh, Tae-Kwang|Kim, Jae Wha|Wilson, Ian A|Kim, Myung Hee
PMID: 21247902
Journal: Biochem Biophys Res Commun. 2011 Mar 25;406(4):534-8.
Title: Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650.
Author: Feng, Li|Xie, Yun|Zhang, Hao|Wu, Yunlin
PMID: 21352815
Journal: PLoS One. 2012;7(10):e43044.
Title: FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
Author: Deuschle, Ulrich|Schuler, Julia|Schulz, Andreas|Schluter, Thomas|Kinzel, Olaf|Abel, Ulrich|Kremoser, Claus
PMID: 23056173
Journal: Oncol Rep. 2013 Oct;30(4):1890-8.
Title: NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients.
Author: Kim, Young-Jun|Kang, Ho-Bum|Yim, Hyun Sun|Kim, Joo Heon|Kim, Jae Wha
PMID: 23900729
Journal: Med Oncol. 2013 Mar;30(1):421.
Title: Expression of NDRG2 in human lung cancer and its correlation with prognosis.
Author: Li, Shu-Jun|Wang, Wen-Yong|Li, Bing|Chen, Bei|Zhang, Bo|Wang, Xin|Chen, Chang-Sheng|Zhao, Qing-Chuan|Shi, Hai|Yao, Libo
PMID: 23307246
Journal: Oncogenesis. 2014 Feb 3;3:e86.
Title: Tumor suppressor NDRG2 tips the balance of oncogenic TGF-beta via EMT inhibition in colorectal cancer.
Author: Shen, L|Qu, X|Ma, Y|Zheng, J|Chu, D|Liu, B|Li, X|Wang, M|Xu, C|Liu, N|Yao, L|Zhang, J
PMID: 24492480
Journal: Mol Med Rep. 2014 Aug;10(2):891-6.
Title: Tumor suppressor candidate gene, NDRG2 is frequently inactivated in human glioblastoma multiforme.
Author: Zhou, Bin|Tang, Zhuo|Deng, Yanchun|Hou, Shuangxing|Liu, Nan|Lin, Wei|Liu, Xinping|Yao, Libo
PMID: 24840052
Journal: Oncotarget. 2015 Sep 22;6(28):26161-76.
Title: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression.
Author: Xu, Xinyuan|Li, Jianying|Sun, Xiang|Guo, Yan|Chu, Dake|Wei, Li|Li, Xia|Yang, Guodong|Liu, Xinping|Yao, Libo|Zhang, Jian|Shen, Lan
PMID: 26317652
Journal: Iran J Med Sci. 2015 Sep;40(5):430-9.
Title: The Effects of NDRG2 Overexpression on Cell Proliferation and Invasiveness of SW48 Colorectal Cancer Cell Line.
Author: Golestan, Ali MSc|Mojtahedi, Zahra PhD|Ghalamfarsa, Ghasem PhD|Hamidinia, Maryam MSc|Takhshid, Mohammad Ali PhD
PMID: 26379350
Journal: J Gastroenterol Hepatol. 2016 Jan;31(1):164-71.
Title: Epigenetic silencing of NDRG2 promotes colorectal cancer proliferation and invasion.
Author: Hong, Sung Noh|Kim, Sung Jin|Kim, Eun-Ran|Chang, Dong Kyung|Kim, Young-Ho
PMID: 26250123
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Jan;33(1):48-52.
Title: [Overexpression of N-myc downstream regulated gene 2 (NDRG2) inhibits proliferation, migration and promotes apoptosis in SW480 rectal cancer cells].
Author: Li, Zhiqiang|Sun, Yang|Wan, Hongxing|Chai, Fang
PMID: 28031114
Journal: World J Clin Oncol. 2017 Feb 10;8(1):67-74.
Title: NDRG2 gene copy number is not altered in colorectal carcinoma.
Author: Lorentzen, Anders|Mitchelmore, Cathy
PMID: 28246586
Journal: Oncol Rep. 2017 Aug;38(2):975-984.
Title: KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling.
Author: Ma, Yongzheng|Wu, Lin|Liu, Xuewu|Xu, Yuqiao|Shi, Wei|Liang, Ye|Yao, Libo|Zheng, Jianyong|Zhang, Jian
PMID: 28656310
Journal: Adv Pharm Bull. 2017 Dec;7(4):661-664.
Title: Effects of NDRG2 Overexpression on Metastatic Behaviors of HCT116 Colorectal Cancer Cell Line.
Author: Golestan, Ali|Ghaderi, Abbas|Mojtahedi, Zahra
PMID: 29399558
Journal: Oncogene. 2018 Mar;37(13):1759-1774.
Title: NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis.
Author: Shen, Liangliang|Qu, Xuan|Li, Huichen|Xu, Chunsheng|Wei, Mengying|Wang, Qinhao|Ru, Yi|Liu, Bei|Xu, Yuqiao|Li, Kai|Hu, Junbi|Wang, Lifeng|Ma, Yongzheng|Li, Mengyang|Lai, Xiaofeng|Gao, Lei|Wu, Kaichun|Yao, Libo|Zheng, Jianyong|Zhang, Jian
PMID: 29343851
Journal: Cell Death Dis. 2018 Feb 14;9(2):248.
Title: Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization.
Author: Li, Mengyang|Lai, Xiaofeng|Zhao, Ying|Zhang, Yuan|Li, Minghui|Li, Danxiu|Kong, Jing|Zhang, Yong|Jing, Pengyu|Li, Huichen|Qin, Hongyan|Shen, Liangliang|Yao, Libo|Li, Jipeng|Dou, Kefeng|Zhang, Jian
PMID: 29445150
Journal: Biochim Biophys Acta Gen Subj. 2018 Jul 7;1862(10):2140-2151.
Title: A combined literature and in silico analysis enlightens the role of the NDRG family in the gut.
Author: Vaes, Nathalie|Schonkeren, Simone L|Brosens, Erwin|Koch, Alexander|McCann, Conor J|Thapar, Nikhil|Hofstra, Robert M W|van Engeland, Manon|Melotte, Veerle
PMID: 30033230