Primary Site >> Colorectal Cancer
Gene >> NDRG2
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Ref: Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma. PMID: 17935612 |
Ref: [Expression of candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colon cancer]. PMID: 18636358 |
Ref: NDRG2 suppresses cell proliferation through down-regulation of AP-1 activity in human colon carcinoma cells. PMID: 18844221 Ref: NDRG2 expression decreases with tumor stages and regulates TCF/beta-catenin signaling in human colon carcinoma. PMID: 19237607 Ref: Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour. PMID: 19257893 Ref: [Expression and significance of new candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colorectal cancer]. PMID: 19434539 Ref: Suppression of N-myc downstream-regulated gene 2 is associated with induction of Myc in colorectal cancer and correlates closely with differentiation. PMID: 19483300 |
Ref: Prediction of colorectal cancer relapse and prognosis by tissue mRNA levels of NDRG2. PMID: 21220491 Ref: Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. PMID: 21247902 Ref: Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650. PMID: 21352815 |
Ref: FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model. PMID: 23056173 |
Ref: Expression of NDRG2 in human lung cancer and its correlation with prognosis. PMID: 23307246 Ref: NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients. PMID: 23900729 |
Ref: Tumor suppressor NDRG2 tips the balance of oncogenic TGF-beta via EMT inhibition in colorectal cancer. PMID: 24492480 Ref: Tumor suppressor candidate gene, NDRG2 is frequently inactivated in human glioblastoma multiforme. PMID: 24840052 |
Ref: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. PMID: 26317652 Ref: The Effects of NDRG2 Overexpression on Cell Proliferation and Invasiveness of SW48 Colorectal Cancer Cell Line. PMID: 26379350 |
Ref: Epigenetic silencing of NDRG2 promotes colorectal cancer proliferation and invasion. PMID: 26250123 |
Ref: [Overexpression of N-myc downstream regulated gene 2 (NDRG2) inhibits proliferation, migration and promotes apoptosis in SW480 rectal cancer cells]. PMID: 28031114 Ref: NDRG2 gene copy number is not altered in colorectal carcinoma. PMID: 28246586 Ref: KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling. PMID: 28656310 Ref: Effects of NDRG2 Overexpression on Metastatic Behaviors of HCT116 Colorectal Cancer Cell Line. PMID: 29399558 |
Ref: NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. PMID: 29343851 Ref: Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization. PMID: 29445150 Ref: A combined literature and in silico analysis enlightens the role of the NDRG family in the gut. PMID: 30033230 |