Primary Site >> Colorectal Cancer

Gene >> NCK1

Journal: J Biol Chem. 2002 Oct 4;277(40):37788-97. Epub 2002 Jul 30.
Title: The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism.
Author: Li, Xiaodong|Meriane, Mayya|Triki, Ibtissem|Shekarabi, Masoud|Kennedy, Timothy E|Larose, Louise|Lamarche-Vane, Nathalie
PMID: 12149262
Journal: J Neurosci. 2005 Mar 23;25(12):3132-41.
Title: Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion.
Author: Shekarabi, Masoud|Moore, Simon W|Tritsch, Nicolas X|Morris, Stephen J|Bouchard, Jean-Francois|Kennedy, Timothy E
PMID: 15788770
Journal: Biol Cell. 2009 Feb;101(2):77-90.
Title: Compartmentalized DCC signalling is distinct from DCC localized to lipid rafts.
Author: Petrie, Ryan J|Zhao, Beibei|Bedford, Fiona|Lamarche-Vane, Nathalie
PMID: 18616430
Journal: J Neurochem. 2015 Sep;134(6):1008-14.
Title: NCK is critical for the development of deleted in colorectal cancer (DCC) sensitive spinal circuits.
Author: Lane, Ciaran|Qi, Jiansong|Fawcett, James P
PMID: 25913325
Journal: Cell Signal. 2017 Aug;36:67-78.
Title: Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.
Author: Zhang, Fan|Lu, Yan-Xia|Chen, Qing|Zou, Hui-Mei|Zhang, Jian-Ming|Hu, Yu-Han|Li, Xiao-Min|Zhang, Wen-Juan|Zhang, Wei|Lin, Chun|Li, Xue-Nong
PMID: 28455144