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Journal: Oncogene. 1999 Jun 3;18(22):3422-6.
Title: Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer.
Author: Hiramoto, T|Nakanishi, T|Sumiyoshi, T|Fukuda, T|Matsuura, S|Tauchi, H|Komatsu, K|Shibasaki, Y|Inui, H|Watatani, M|Yasutomi, M|Sumii, K|Kajiyama, G|Kamada, N|Miyagawa, K|Kamiya, K
PMID: 10362364
Journal: Oncol Rep. 2000 Mar-Apr;7(2):427-31.
Title: Allelic imbalance at NBS1 is frequent in both proximal and distal colorectal carcinoma.
Author: Uhrhammer, N|Bay, J O|Gosse-Brun, S|Kwiatkowski, F|Rio, P|Daver, A|Bignon, Y J
PMID: 10671697
Journal: EMBO Rep. 2002 Mar;3(3):248-54. Epub 2002 Feb 15.
Title: Human MRE11 is inactivated in mismatch repair-deficient cancers.
Author: Giannini, Giuseppe|Ristori, Elisabetta|Cerignoli, Fabio|Rinaldi, Christian|Zani, Massimo|Viel, Alessandra|Ottini, Laura|Crescenzi, Marco|Martinotti, Stefano|Bignami, Margherita|Frati, Luigi|Screpanti, Isabella|Gulino, Alberto
PMID: 11850399
Journal: Oncol Rep. 2002 Jul-Aug;9(4):709-11.
Title: Nijmegen breakage syndrome gene (NBS1) is not the tumor suppressor gene at 8q21.3 involved in colorectal carcinoma.
Author: Varon, Raymonda|Gosse-Brun, Sandrine|Bignon, Yves-Jean|Sperling, Karl|Uhrhammer, Nancy
PMID: 12066197
Journal: Oncogene. 2004 Apr 8;23(15):2640-7.
Title: Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability.
Author: Giannini, Giuseppe|Rinaldi, Christian|Ristori, Elisabetta|Ambrosini, Maria Irene|Cerignoli, Fabio|Viel, Alessandra|Bidoli, Ettore|Berni, Silvia|D'Amati, Giulia|Scambia, Giovanni|Frati, Luigi|Screpanti, Isabella|Gulino, Alberto
PMID: 15048091
Journal: Int J Cancer. 2004 Aug 10;111(1):67-71.
Title: Increased cancer risk of heterozygotes with NBS1 germline mutations in Poland.
Author: Steffen, Jan|Varon, Raymonda|Mosor, Maria|Maneva, Galina|Maurer, Martin|Stumm, Markus|Nowakowska, Dorota|Rubach, Maryna|Kosakowska, Ewa|Ruka, Wlodzimierz|Nowecki, Zbigniew|Rutkowski, Piotr|Demkow, Tomasz|Sadowska, Malgorzata|Bidzinski, Mariusz|Gawrychowsk
PMID: 15185344
Journal: J Biol Chem. 2004 Sep 17;279(38):39584-92. Epub 2004 Jul 20.
Title: ATM-dependent CHK2 activation induced by anticancer agent, irofulven.
Author: Wang, Jian|Wiltshire, Timothy|Wang, Yutian|Mikell, Carmenza|Burks, Julian|Cunningham, Cynthia|Van Laar, Emily S|Waters, Stephen J|Reed, Eddie|Wang, Weixin
PMID: 15269203
Journal: Lab Invest. 2005 Sep;85(9):1130-8.
Title: Impaired nonhomologous end-joining in mismatch repair-deficient colon carcinomas.
Author: Koh, Kwi H|Kang, Hyun J|Li, Long S|Kim, Nam-Gyun|You, Kwon T|Yang, Eungi|Kim, Hyunki|Kim, Hee J|Yun, Chae-Ok|Kim, Kyung-Sup|Kim, Hoguen
PMID: 16025146
Journal: Cas Lek Cesk. 2006;145(3):201-3.
Title: [Mutations in tumor suppressor gene NBS1 in adult patients with malignancies].
Author: Seemanova, E|Hoch, J|Herzogova, J|Kawaciuk, I|Janda, J|Kohoutova, M|Seeman, P|Varon, R|Sperling, K
PMID: 16634478
Journal: J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.
Title: Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Author: Takemura, Haruyuki|Rao, V Ashutosh|Sordet, Olivier|Furuta, Takahisa|Miao, Ze-Hong|Meng, Linghua|Zhang, Hongliang|Pommier, Yves
PMID: 16905549
Journal: Cancer Biol Ther. 2007 Feb;6(2):160-9. Epub 2007 Feb 5.
Title: Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.
Author: Roepke, Martin|Diestel, Antje|Bajbouj, Khuloud|Walluscheck, Diana|Schonfeld, Peter|Roessner, Albert|Schneider-Stock, Regine|Gali-Muhtasib, Hala
PMID: 17218778
Journal: Eur J Hum Genet. 2007 Sep;15(9):922-9. Epub 2007 May 30.
Title: The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients.
Author: Alemayehu, Aster|Fridrichova, Ivana
PMID: 17534377
Journal: Cancer Res. 2007 Dec 1;67(23):11158-65.
Title: Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer.
Author: Ebi, Hiromichi|Matsuo, Keitaro|Sugito, Nobuyoshi|Suzuki, Motoshi|Osada, Hirotaka|Tajima, Kazuo|Ueda, Ryuzo|Takahashi, Takashi
PMID: 18056440
Journal: Eur J Cancer. 2008 Mar;44(4):627-30.
Title: Heterozygous carriers of the I171V mutation of the NBS1 gene have a significantly increased risk of solid malignant tumours.
Author: Nowak, Jerzy|Mosor, Maria|Ziolkowska, Iwona|Wierzbicka, Malgorzta|Pernak-Schwarz, Monika|Przyborska, Marta|Roznowski, Krzysztof|Plawski, Andrzej|Slomski, Ryszard|Januszkiewicz, Danuta
PMID: 18280732
Journal: Mutat Res. 2008 Sep-Oct;659(3):262-73.
Title: The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer.
Author: Dzikiewicz-Krawczyk, Agnieszka
PMID: 18606567
Journal: Histol Histopathol. 2008 Dec;23(12):1495-502.
Title: RAD50/MRE11/NBS1 proteins in relation to tumour development and prognosis in patients with microsatellite stable colorectal cancer.
Author: Gao, Jingfang|Zhang, Hong|Arbman, Gunnar|Sun, Xiao-Feng
PMID: 18830935
Journal: Curr Genomics. 2008 Jun;9(4):275-81.
Title: NBS1 Heterozygosity and Cancer Risk.
Author: di Masi, Alessandra|Antoccia, Antonio
PMID: 19452044
Journal: Mutat Res. 2009 Jun 18;666(1-2):64-7.
Title: NBN 657del5 heterozygous mutations and colorectal cancer risk in the Czech Republic.
Author: Pardini, Barbara|Naccarati, Alessio|Polakova, Veronika|Smerhovsky, Zdenek|Hlavata, Ivona|Soucek, Pavel|Novotny, Jan|Vodickova, Ludmila|Tomanova, Vera|Landi, Stefano|Vodicka, Pavel
PMID: 19393249
Journal: Int J Mol Med. 2010 Mar;25(3):321-9.
Title: Expression profile of significant immortalization genes in colon cancer.
Author: Witkowska, Agnieszka|Gumprecht, Janusz|Glogowska-Ligus, Joanna|Wystrychowski, Grzegorz|Owczarek, Aleksander|Stachowicz, Malgorzata|Bocianowska, Alina|Nowakowska-Zajdel, Ewa|Mazurek, Urszula
PMID: 20127035
Journal: J Appl Genet. 2010;51(3):343-52.
Title: Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population.
Author: Jelonek, K|Gdowicz-Klosok, A|Pietrowska, M|Borkowska, M|Korfanty, J|Rzeszowska-Wolny, J|Widlak, P
PMID: 20720310
Journal: Tumori. 2010 Nov-Dec;96(6):1004-9.
Title: Novel somatic frameshift mutations of genes related to cell cycle and DNA damage response in gastric and colorectal cancers with microsatellite instability.
Author: Kim, Yoo Ri|Chung, Nak Gyun|Kang, Mi Ran|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 21388066
Journal: Cell Death Dis. 2011 Mar 10;2:e128.
Title: Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.
Author: So, E Y|Ausman, M|Saeki, T|Ouchi, T
PMID: 21390062
Journal: Cas Lek Cesk. 2011;150(2):97-9.
Title: [Heterozygous carriers of Slavic mutation 657del5 of NBN gene in patients with colorectal cancer].
Author: Seemanova, Eva|Hoch, Jiri|Seeman, Pavel
PMID: 21560448
Journal: Oncotarget. 2012 Aug;3(8):854-68.
Title: Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
Author: Agyeman, Akwasi|Mazumdar, Tapati|Houghton, Janet A
PMID: 23097684
Journal: Tumour Biol. 2013 Aug;34(4):2141-6.
Title: Clinicopathological significance of BTF3 expression in colorectal cancer.
Author: Wang, Chao-Jie|Franbergh-Karlson, Hanna|Wang, Da-Wei|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 23532689
Journal: Mutat Res. 2013 Jul 4;755(1):42-8.
Title: The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays.
Author: Gdowicz-Klosok, Agnieszka|Widel, Maria|Rzeszowska-Wolny, Joanna
PMID: 23669291
Journal: Mol Carcinog. 2014 Sep;53(9):744-52.
Title: Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer.
Author: Boulware, Stephen B|Christensen, Laura A|Thames, Howard|Coghlan, Lezlee|Vasquez, Karen M|Finch, Rick A
PMID: 23681918
Journal: Cancer Biol Ther. 2014;15(12):1700-4.
Title: Distinct DNA damage determines differential phosphorylation of Chk2.
Author: Ouchi, Mutsuko|Ouchi, Toru
PMID: 25535901
Journal: PLoS One. 2015 Jul 17;10(7):e0132332.
Title: Associations between NBS1 Polymorphisms and Colorectal Cancer in Chinese Population.
Author: Li, Jing-Tao|Zhong, Bao-Yuan|Xu, Hui-Hui|Qiao, Sheng-Yan|Wang, Gui|Huang, Jing|Fan, Hui-Zhen|Zhao, Hong-Chuan
PMID: 26186548
Journal: Sci Rep. 2016 Nov 15;6:36874.
Title: rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.
Author: Liu, Jingjing|Loncar, Ivona|Collee, J Margriet|Bolla, Manjeet K|Dennis, Joe|Michailidou, Kyriaki|Wang, Qin|Andrulis, Irene L|Barile, Monica|Beckmann, Matthias W|Behrens, Sabine|Benitez, Javier|Blomqvist, Carl|Boeckx, Bram|Bogdanova, Natalia V|Bojesen, Sti
PMID: 27845421
Journal: Oncogene. 2018 Jan 25;37(4):427-438.
Title: AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.
Author: Piscitello, D|Varshney, D|Lilla, S|Vizioli, M G|Reid, C|Gorbunova, V|Seluanov, A|Gillespie, D A|Adams, P D
PMID: 28967905
Journal: Neoplasma. 2018;65(1):75-80.
Title: Targeting RAD50 increases sensitivity to radiotherapy in colorectal cancer cells.
Author: Chen, C|Wang, Y|Mei, J F|Li, S S|Xu, H X|Xiong, H P|Wang, X H|He, X
PMID: 29322791
Journal: Oncotarget. 2018 May 8;9(35):23960-23974.
Title: Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Author: Oliveira, Duarte Mendes|Laudanna, Carmelo|Migliozzi, Simona|Zoppoli, Pietro|Santamaria, Gianluca|Grillone, Katia|Elia, Laura|Mignogna, Chiara|Biamonte, Flavia|Sacco, Rosario|Corcione, Francesco|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia
PMID: 29844865
Journal: BMC Cancer. 2018 Sep 3;18(1):869.
Title: Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis.
Author: Ho, Vincent|Chung, Liping|Singh, Amandeep|Lea, Vivienne|Abubakar, Askar|Lim, Stephanie H|Ng, Weng|Lee, Mark|de Souza, Paul|Shin, Joo-Shik|Lee, Cheok Soon
PMID: 30176843