Primary Site >> Liver Cancer
Gene >> NANOG
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2445-50. | ||||||||||
| Title: | Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. | ||||||||||
| Author: | Tang, Yi|Kitisin, Krit|Jogunoori, Wilma|Li, Cuiling|Deng, Chu-Xia|Mueller, Susette C|Ressom, Habtom W|Rashid, Asif|He, Aiwu Ruth|Mendelson, Jonathan S|Jessup, John M|Shetty, Kirti|Zasloff, Michael|Mishra, Bibhuti|Reddy, E P|Johnson, Lynt|Mishra, Lopa | ||||||||||
| PMID: | 18263735 | ||||||||||
| 2. | |||||||||||
| Journal: | BMC Med Genomics. 2008 Oct 10;1:49. | ||||||||||
| Title: | The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines. | ||||||||||
| Author: | Regenbrecht, Christian Ra|Jung, Marc|Lehrach, Hans|Adjaye, James | ||||||||||
| PMID: | 18847459 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastrointest Cancer Res. 2008 Jul;2(4 Suppl):S27-30. | ||||||||||
| Title: | Liver stem cells and tgf-Beta in hepatic carcinogenesis. | ||||||||||
| Author: | Amin, Rupen|Mishra, Lopa | ||||||||||
| PMID: | 19343145 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2009 Feb 19;28(7):961-72. | ||||||||||
| Title: | The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-beta signaling. | ||||||||||
| Author: | Lin, L|Amin, R|Gallicano, G I|Glasgow, E|Jogunoori, W|Jessup, J M|Zasloff, M|Marshall, J L|Shetty, K|Johnson, L|Mishra, L|He, A R | ||||||||||
| PMID: | 19137011 | ||||||||||
| 5. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1548-53. | ||||||||||
| Title: | Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog. | ||||||||||
| Author: | Machida, Keigo|Tsukamoto, Hidekazu|Mkrtchyan, Hasmik|Duan, Lewei|Dynnyk, Alla|Liu, Helene Minyi|Asahina, Kinji|Govindarajan, Sugantha|Ray, Ratna|Ou, Jing-Hsiung James|Seki, Ekihiro|Deshaies, Raymond|Miyake, Kensuke|Lai, Michael M-C | ||||||||||
| PMID: | 19171902 | ||||||||||
| 6. | |||||||||||
| Journal: | Carcinogenesis. 2010 Feb;31(2):167-74. | ||||||||||
| Title: | The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. | ||||||||||
| Author: | Xu, Xiao-Lan|Xing, Bao-Cai|Han, Hai-Bo|Zhao, Wei|Hu, Mei-Hao|Xu, Zuo-Liang|Li, Ji-You|Xie, Yong|Gu, Jun|Wang, Yu|Zhang, Zhi-Qian | ||||||||||
| PMID: | 19897602 | ||||||||||
| 7. | |||||||||||
| Journal: | Exp Mol Pathol. 2010 Jun;88(3):331-40. | ||||||||||
| Title: | The identification of stem cells in human liver diseases and hepatocellular carcinoma. | ||||||||||
| Author: | Oliva, Joan|French, Barbara A|Qing, X|French, Samuel W | ||||||||||
| PMID: | 20080086 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Cell Biochem. 2010 Oct;343(1-2):155-62. | ||||||||||
| Title: | Expression of Oct4 in HCC and modulation to wnt/beta-catenin and TGF-beta signal pathways. | ||||||||||
| Author: | Yuan, FangJun|Zhou, Wenbo|Zou, Can|Zhang, Zhiyun|Hu, Hongsheng|Dai, Zongqing|Zhang, YouShun | ||||||||||
| PMID: | 20549546 | ||||||||||
| 9. | |||||||||||
| Journal: | Hepatology. 2011 Apr;53(4):1192-205. | ||||||||||
| Title: | Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. | ||||||||||
| Author: | Schrader, Jorg|Gordon-Walker, Timothy T|Aucott, Rebecca L|van Deemter, Marielle|Quaas, Alexander|Walsh, Shaun|Benten, Daniel|Forbes, Stuart J|Wells, Rebecca G|Iredale, John P | ||||||||||
| PMID: | 21442631 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2011 May 15;71(10):3701-8. | ||||||||||
| Title: | Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells? | ||||||||||
| Author: | Arzumanyan, Alla|Friedman, Tiffany|Ng, Irene O L|Clayton, Marcia M|Lian, Zhaorui|Feitelson, Mark A | ||||||||||
| PMID: | 21464043 | ||||||||||
| 11. | |||||||||||
| Journal: | Cell Stem Cell. 2011 Jul 8;9(1):50-63. | ||||||||||
| Title: | CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation. | ||||||||||
| Author: | Lee, Terence Kin Wah|Castilho, Antonia|Cheung, Vincent Chi Ho|Tang, Kwan Ho|Ma, Stephanie|Ng, Irene Oi Lin | ||||||||||
| PMID: | 21726833 | ||||||||||
| 12. | |||||||||||
| Journal: | BMC Cancer. 2011 Sep 19;11:396. | ||||||||||
| Title: | Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics. | ||||||||||
| Author: | Dang, Hien|Ding, Wei|Emerson, Dow|Rountree, C Bart | ||||||||||
| PMID: | 21929801 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2011;6(12):e28246. | ||||||||||
| Title: | Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells. | ||||||||||
| Author: | Cheung, Phyllis Fung Yi|Cheng, Christine Kei Chin|Wong, Nicholas Chun Lim|Ho, Jenny Chung Yee|Yip, Chi Wai|Lui, Vincent Chi Hang|Cheung, Annie Nga Yin|Fan, Sheung Tat|Cheung, Siu Tim | ||||||||||
| PMID: | 22194816 | ||||||||||
| 14. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:19-22. | ||||||||||
| Title: | Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus. | ||||||||||
| Author: | Machida, Keigo|Chen, Chia-Lin|Liu, Jian-Chang|Kashiwabara, Claudine|Feldman, Douglas|French, Samuel W|Sher, Linda|Hyeongnam, Jeong Joseph|Tsukamoto, Hidekazu | ||||||||||
| PMID: | 22320911 | ||||||||||
| 15. | |||||||||||
| Journal: | Ann Surg Oncol. 2012 Sep;19(9):2877-87. | ||||||||||
| Title: | Coexpression of stemness factors Oct4 and Nanog predict liver resection. | ||||||||||
| Author: | Yin, Xin|Li, Yi-Wei|Zhang, Bo-Heng|Ren, Zheng-Gang|Qiu, Shuang-Jian|Yi, Yong|Fan, Jia | ||||||||||
| PMID: | 22461131 | ||||||||||
| 16. | |||||||||||
| Journal: | Hepatology. 2012 Sep;56(3):1004-14. | ||||||||||
| Title: | Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma. | ||||||||||
| Author: | Shan, Juanjuan|Shen, Junjie|Liu, Limei|Xia, Feng|Xu, Chuan|Duan, Guangjie|Xu, Yanmin|Ma, Qinghua|Yang, Zhi|Zhang, Qianzhen|Ma, Leina|Liu, Jia|Xu, Senlin|Yan, Xiaochu|Bie, Ping|Cui, Youhong|Bian, Xiu-wu|Qian, Cheng | ||||||||||
| PMID: | 22473773 | ||||||||||
| 17. | |||||||||||
| Journal: | Dig Dis Sci. 2012 Sep;57(9):2340-6. | ||||||||||
| Title: | Nanog: a potential biomarker for liver metastasis of colorectal cancer. | ||||||||||
| Author: | Xu, Feng|Dai, Chaoliu|Zhang, Rui|Zhao, Yang|Peng, Songlin|Jia, Changjun | ||||||||||
| PMID: | 22562535 | ||||||||||
| 18. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2012 Jun 8;422(3):429-35. | ||||||||||
| Title: | Exploring stemness gene expression and vasculogenic mimicry capacity in well- and poorly-differentiated hepatocellular carcinoma cell lines. | ||||||||||
| Author: | Lirdprapamongkol, Kriengsak|Chiablaem, Khajeelak|Sila-Asna, Monnipha|Surarit, Rudee|Bunyaratvej, Ahnond|Svasti, Jisnuson | ||||||||||
| PMID: | 22580004 | ||||||||||
| 19. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2012 Dec 25;92(48):3434-7. | ||||||||||
| Title: | [A new method for purification and identification of hepatocellular carcinoma stem cell of SMMC-7721]. | ||||||||||
| Author: | Wang, Yong|Liu, Ya-hui|Jiang, Jian-shuai|Cui, Han-bin | ||||||||||
| PMID: | 23327707 | ||||||||||
| 20. | |||||||||||
| Journal: | Cell Cycle. 2013 Jan 15;12(2):353-64. | ||||||||||
| Title: | The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming. | ||||||||||
| Author: | Marzi, Ilaria|Cipolleschi, Maria Grazia|D'Amico, Massimo|Stivarou, Theodora|Rovida, Elisabetta|Vinci, Maria Cristina|Pandolfi, Silvia|Dello Sbarba, Persio|Stecca, Barbara|Olivotto, Massimo | ||||||||||
| PMID: | 23287475 | ||||||||||
| 21. | |||||||||||
| Journal: | Gastroenterology. 2013 May;144(5):1031-1041.e10. | ||||||||||
| Title: | Expression of intercellular adhesion molecule 1 by hepatocellular carcinoma stem cells and circulating tumor cells. | ||||||||||
| Author: | Liu, Shupeng|Li, Nan|Yu, Xiya|Xiao, Xiao|Cheng, Kai|Hu, Jingjing|Wang, Jiaqi|Zhang, Dandan|Cheng, Shuqun|Liu, Shanrong | ||||||||||
| PMID: | 23376424 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2013 Jun;45(6):1099-108. | ||||||||||
| Title: | NANOG promotes liver cancer cell invasion by inducing epithelial-mesenchymal transition through NODAL/SMAD3 signaling pathway. | ||||||||||
| Author: | Sun, Chun|Sun, Lu|Jiang, Kai|Gao, Dong-Mei|Kang, Xiao-Nan|Wang, Cun|Zhang, Shu|Huang, Shan|Qin, Xue|Li, Yan|Liu, Yin-Kun | ||||||||||
| PMID: | 23474366 | ||||||||||
| 23. | |||||||||||
| Journal: | BMC Cancer. 2013 Apr 2;13:176. | ||||||||||
| Title: | Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities. | ||||||||||
| Author: | Marfels, Christian|Hoehn, Miriam|Wagner, Ernst|Gunther, Michael | ||||||||||
| PMID: | 23547746 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncol Lett. 2013 Apr;5(4):1155-1162. | ||||||||||
| Title: | The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma. | ||||||||||
| Author: | Yin, Xin|Li, Yi-Wei|Jin, Jian-Jun|Zhou, Yin|Ren, Zheng-Gang|Qiu, Shuang-Jian|Zhang, Bo-Heng | ||||||||||
| PMID: | 23599755 | ||||||||||
| 25. | |||||||||||
| Journal: | J Clin Invest. 2013 Jul;123(7):2832-49. | ||||||||||
| Title: | Reciprocal regulation by TLR4 and TGF-beta in tumor-initiating stem-like cells. | ||||||||||
| Author: | Chen, Chia-Lin|Tsukamoto, Hidekazu|Liu, Jian-Chang|Kashiwabara, Claudine|Feldman, Douglas|Sher, Linda|Dooley, Steven|French, Samuel W|Mishra, Lopa|Petrovic, Lydia|Jeong, Joseph H|Machida, Keigo | ||||||||||
| PMID: | 23921128 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2013 Sep 4;8(9):e72435. | ||||||||||
| Title: | Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. | ||||||||||
| Author: | Wang, Xiao Qi|Ng, Ray Kit|Ming, Xiaoyan|Zhang, Wu|Chen, Lin|Chu, Andrew C Y|Pang, Roberta|Lo, Chung Mau|Tsao, Sai Wah|Liu, Xuqing|Poon, Ronnie T P|Fan, Sheung Tat | ||||||||||
| PMID: | 24023739 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2013 Nov 14;8(11):e80053. | ||||||||||
| Title: | Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma. | ||||||||||
| Author: | Cheng, Shu-Wen|Tsai, Hung-Wen|Lin, Yih-Jyh|Cheng, Pin-Nan|Chang, Yu-Chung|Yen, Chia-Jui|Huang, Hsuan-Pang|Chuang, Yun-Pei|Chang, Ting-Tsung|Lee, Chung-Ta|Chao, Anning|Chou, Cheng-Yang|Chan, Shih-Huang|Chow, Nan-Haw|Ho, Chung-Liang | ||||||||||
| PMID: | 24244607 | ||||||||||
| 28. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Dec 21;19(47):8850-60. | ||||||||||
| Title: | Cellular reprogramming and hepatocellular carcinoma development. | ||||||||||
| Author: | Zheng, Yun-Wen|Nie, Yun-Zhong|Taniguchi, Hideki | ||||||||||
| PMID: | 24379607 | ||||||||||
| 29. | |||||||||||
| Journal: | Drug Deliv Transl Res. 2013 Apr;3(2):152-64. | ||||||||||
| Title: | Tumor-initiating stem-like cells and drug resistance: carcinogenesis through Toll-like receptors, environmental factors, and virus. | ||||||||||
| Author: | Machida, Keigo | ||||||||||
| PMID: | 25787983 | ||||||||||
| 30. | |||||||||||
| Journal: | Carcinogenesis. 2014 Mar;35(3):537-45. | ||||||||||
| Title: | Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24. | ||||||||||
| Author: | Liu, Allan Yi|Cai, Yao|Mao, Yubin|Lin, Yancheng|Zheng, Hong|Wu, Tiantian|Huang, Yangmei|Fang, Xiaoguang|Lin, Shuyong|Feng, Qingzhao|Huang, Zhengjie|Yang, Tianci|Luo, Qi|Ouyang, Gaoliang | ||||||||||
| PMID: | 24193512 | ||||||||||
| 31. | |||||||||||
| Journal: | FEBS Lett. 2014 Feb 14;588(4):566-73. | ||||||||||
| Title: | Hepatitis C virus core protein regulates NANOG expression via the stat3 pathway. | ||||||||||
| Author: | Zhou, Jia-Jia|Chen, Ru-Fu|Deng, Xiao-Geng|Zhou, Yu|Ye, Xiao|Yu, Min|Tang, Jing|He, Xiao-Yu|Cheng, Di|Zeng, Bing|Zhou, Quan-bo|Li, Zhi-hua | ||||||||||
| PMID: | 24462277 | ||||||||||
| 32. | |||||||||||
| Journal: | Asian Pac J Trop Med. 2014 Apr;7(4):253-6. | ||||||||||
| Title: | Establishment and identification of induced pluripotent stem cells in liver cancer patients. | ||||||||||
| Author: | Zhang, Da-Ming|Li, Jian-Jun|Yan, Peng|Hu, Jian-Ting | ||||||||||
| PMID: | 24507670 | ||||||||||
| 33. | |||||||||||
| Journal: | Int J Cancer. 2014 Oct 15;135(8):1790-9. | ||||||||||
| Title: | Overexpression of ZFX confers self-renewal and chemoresistance properties in hepatocellular carcinoma. | ||||||||||
| Author: | Lai, Keng Po|Chen, Jiawei|He, Mian|Ching, Arthur K K|Lau, Coleen|Lai, Paul B S|To, Ka-Fai|Wong, Nathalie | ||||||||||
| PMID: | 24585547 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Oncol. 2014 Jun;44(6):2034-40. | ||||||||||
| Title: | Knockdown of NANOG enhances chemosensitivity of liver cancer cells to doxorubicin by reducing MDR1 expression. | ||||||||||
| Author: | Zhou, Jia-Jia|Deng, Xiao-Geng|He, Xiao-Yu|Zhou, Yu|Yu, Min|Gao, Wen-Chao|Zeng, Bing|Zhou, Quan-Bo|Li, Zhi-Hua|Chen, Ru-Fu | ||||||||||
| PMID: | 24647772 | ||||||||||
| 35. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Jun 14;20(22):6974-80. | ||||||||||
| Title: | Influence of adriamycin on changes in Nanog, Oct-4, Sox2, ARID1 and Wnt5b expression in liver cancer stem cells. | ||||||||||
| Author: | Sun, Ding|Qin, Lei|Xu, Yang|Liu, Jian-Xia|Tian, Li-Ping|Qian, Hai-Xin | ||||||||||
| PMID: | 24944491 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Res. 2014 Oct 15;74(20):5903-13. | ||||||||||
| Title: | MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism. | ||||||||||
| Author: | Akita, Hirofumi|Marquardt, Jens U|Durkin, Marian E|Kitade, Mitsuteru|Seo, Daekwan|Conner, Elizabeth A|Andersen, Jesper B|Factor, Valentina M|Thorgeirsson, Snorri S | ||||||||||
| PMID: | 25189530 | ||||||||||
| 37. | |||||||||||
| Journal: | Exp Mol Pathol. 2014 Dec;97(3):399-410. | ||||||||||
| Title: | Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. | ||||||||||
| Author: | Buzzanco, A|Gomez, A|Rodriguez, E|French, B A|Tillman, B A|Chang, S|Ganapathy, E|Junrungsee, S|Zarrinpar, A|Agopian, V G|Naini, B V|French, S W Jr|French, S W Sr | ||||||||||
| PMID: | 25218810 | ||||||||||
| 38. | |||||||||||
| Journal: | BMC Cancer. 2014 Sep 27;14:722. | ||||||||||
| Title: | Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugs. | ||||||||||
| Author: | Hashimoto, Noriaki|Tsunedomi, Ryouichi|Yoshimura, Kiyoshi|Watanabe, Yusaku|Hazama, Shoichi|Oka, Masaaki | ||||||||||
| PMID: | 25260650 | ||||||||||
| 39. | |||||||||||
| Journal: | PLoS One. 2014 Dec 11;9(12):e114912. | ||||||||||
| Title: | A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma. | ||||||||||
| Author: | Marchio, Agnes|Bertani, Stephane|Rojas Rojas, Teresa|Doimi, Franco|Terris, Benoit|Deharo, Eric|Dejean, Anne|Ruiz, Eloy|Pineau, Pascal | ||||||||||
| PMID: | 25502816 | ||||||||||
| 40. | |||||||||||
| Journal: | Hepatol Int. 2014 Sep;8 Suppl 2:408-12. | ||||||||||
| Title: | Alcohol, TLR4-TGF-beta antagonism, and liver cancer. | ||||||||||
| Author: | Tsukamoto, Hidekazu|Mishra, Lopa|Machida, Keigo | ||||||||||
| PMID: | 26201318 | ||||||||||
| 41. | |||||||||||
| Journal: | Hepatol Int. 2014 Jul;8(3):330-8. | ||||||||||
| Title: | Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity. | ||||||||||
| Author: | Chen, Chia-Lin|Tsukamoto, Hidekazu|Machida, Keigo | ||||||||||
| PMID: | 26202636 | ||||||||||
| 42. | |||||||||||
| Journal: | Oncol Rep. 2015 Jan;33(1):149-56. | ||||||||||
| Title: | Slug promotes hepatocellular cancer cell progression by increasing sox2 and nanog expression. | ||||||||||
| Author: | Zhao, Xiulan|Sun, Baocun|Sun, Dan|Liu, Tieju|Che, Na|Gu, Qiang|Dong, Xueyi|Li, Rui|Liu, Yanrong|Li, Jing | ||||||||||
| PMID: | 25339068 | ||||||||||
| 43. | |||||||||||
| Journal: | Adv Exp Med Biol. 2015;815:131-44. | ||||||||||
| Title: | TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis. | ||||||||||
| Author: | Machida, Keigo|Feldman, Douglas E|Tsukamoto, Hidekazu | ||||||||||
| PMID: | 25427905 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Sci. 2015 Feb;106(2):151-9. | ||||||||||
| Title: | TAZ regulates cell proliferation and epithelial-mesenchymal transition of human hepatocellular carcinoma. | ||||||||||
| Author: | Xiao, Heng|Jiang, Ning|Zhou, Baoyong|Liu, Qiang|Du, Chengyou | ||||||||||
| PMID: | 25495189 | ||||||||||
| 45. | |||||||||||
| Journal: | Clin Cancer Res. 2015 Jan 1;21(1):201-10. | ||||||||||
| Title: | Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression. | ||||||||||
| Author: | Chang, Te-Sheng|Wu, Yu-Chih|Chi, Ching-Chi|Su, Wei-Chi|Chang, Pey-Jium|Lee, Kam-Fai|Tung, Tao-Hsin|Wang, Jui|Liu, Jun-Jen|Tung, Shui-Yi|Kuo, Liang-Mou|Ho, Hong-Nerng|Ling, Thai-Yen|Huang, Yen-Hua | ||||||||||
| PMID: | 25564572 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncotarget. 2015 Feb 28;6(6):3669-79. | ||||||||||
| Title: | Notch3 functions as a regulator of cell self-renewal by interacting with the beta-catenin pathway in hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Qingyu|Lu, Caijie|Fang, Tao|Wang, Yongcun|Hu, Wenhua|Qiao, Jie|Liu, Bin|Liu, Jie|Chen, Nianping|Li, Mingyi|Zhu, Runzhi | ||||||||||
| PMID: | 25668819 | ||||||||||
| 47. | |||||||||||
| Journal: | Oncol Rep. 2015 Apr;33(4):1965-75. | ||||||||||
| Title: | OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: a bioinformatic analysis combine with RNAi and oligonucleotide microarray. | ||||||||||
| Author: | Hu, Qiping|Fu, Jun|Luo, Bin|Huang, Miao|Guo, Wenwen|Lin, Yongda|Xie, Xiaoxun|Xiao, Shaowen | ||||||||||
| PMID: | 25673160 | ||||||||||
| 48. | |||||||||||
| Journal: | J Hematol Oncol. 2015 Mar 11;8:23. | ||||||||||
| Title: | Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling. | ||||||||||
| Author: | Yin, Xin|Zhang, Bo-Heng|Zheng, Su-Su|Gao, Dong-Mei|Qiu, Shuang-Jian|Wu, Wei-Zhong|Ren, Zheng-Gang | ||||||||||
| PMID: | 25879771 | ||||||||||
| 49. | |||||||||||
| Journal: | Gastroenterology. 2015 Oct;149(4):1068-81.e5. | ||||||||||
| Title: | Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells. | ||||||||||
| Author: | Song, Yangyang|Pan, Guangjin|Chen, Leilei|Ma, Stephanie|Zeng, Tingting|Man Chan, Tim Hon|Li, Lei|Lian, Qizhou|Chow, Raymond|Cai, Xiujuan|Li, Yan|Li, Yan|Liu, Ming|Li, Yun|Zhu, Yinghui|Wong, Nathalie|Yuan, Yun-Fei|Pei, Duanqing|Guan, Xin-Yuan | ||||||||||
| PMID: | 26099525 | ||||||||||
| 50. | |||||||||||
| Journal: | Hepatology. 2015 Nov;62(5):1466-79. | ||||||||||
| Title: | NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer. | ||||||||||
| Author: | Siddique, Hifzur R|Feldman, Douglas E|Chen, Chia-Lin|Punj, Vasu|Tokumitsu, Hiroshi|Machida, Keigo | ||||||||||
| PMID: | 26174965 | ||||||||||
| 51. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 15;6(27):24163-77. | ||||||||||
| Title: | TACC3 promotes stemness and is a potential therapeutic target in hepatocellular carcinoma. | ||||||||||
| Author: | Zhou, Dong-Sheng|Wang, Hong-Bo|Zhou, Zhong-Guo|Zhang, Yao-Jun|Zhong, Qian|Xu, Li|Huang, Yue-Hua|Yeung, Sai-Ching|Chen, Min-Shan|Zeng, Mu-Sheng | ||||||||||
| PMID: | 26219398 | ||||||||||
| 52. | |||||||||||
| Journal: | Oncotarget. 2015 Nov 10;6(35):37200-15. | ||||||||||
| Title: | Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|Madhoun, Mohammad F|May, Randal|Qu, Dongfeng|Ali, Naushad|Fazili, Javid|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ding, Kai|Lightfoot, Stanley A|Houchen, Courtney W | ||||||||||
| PMID: | 26468984 | ||||||||||
| 53. | |||||||||||
| Journal: | Oncotarget. 2015 Dec 29;6(42):44452-65. | ||||||||||
| Title: | Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation. | ||||||||||
| Author: | Han, Shuo|Guo, Jinhai|Liu, Yinan|Zhang, Zhi|He, Qihua|Li, Peng|Zhang, Mingzhi|Sun, Haojie|Li, Ruizhi|Li, Yang|Zeng, Wotan|Liu, Jinwen|Lian, Lejian|Gao, Yi|Shen, Li | ||||||||||
| PMID: | 26540347 | ||||||||||
| 54. | |||||||||||
| Journal: | Gastroenterology. 2016 Mar;150(3):707-19. | ||||||||||
| Title: | TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. | ||||||||||
| Author: | Uthaya Kumar, Dinesh Babu|Chen, Chia-Lin|Liu, Jian-Chang|Feldman, Douglas E|Sher, Linda S|French, Samuel|DiNorcia, Joseph|French, Samuel W|Naini, Bita V|Junrungsee, Sunhawit|Agopian, Vatche Garen|Zarrinpar, Ali|Machida, Keigo | ||||||||||
| PMID: | 26582088 | ||||||||||
| 55. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Apr 15;22(8):2041-50. | ||||||||||
| Title: | ICAM-1-Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma. | ||||||||||
| Author: | Guo, Weixing|Liu, Shupeng|Cheng, Yuqiang|Lu, Lei|Shi, Jie|Xu, Guixia|Li, Nan|Cheng, Kai|Wu, Mengchao|Cheng, Shuqun|Liu, Shanrong | ||||||||||
| PMID: | 26667486 | ||||||||||
| 56. | |||||||||||
| Journal: | Oncol Rep. 2016 Mar;35(3):1657-63. | ||||||||||
| Title: | TALEN-induced disruption of Nanog expression results in reduced proliferation, invasiveness and migration, increased chemosensitivity and reversal of EMT in HepG2 cells. | ||||||||||
| Author: | Yu, Ai Qing|Ding, Yan|Li, Cheng Lin|Yang, Yi|Yan, Shi Rong|Li, Dong Sheng | ||||||||||
| PMID: | 26676719 | ||||||||||
| 57. | |||||||||||
| Journal: | Cell Metab. 2016 Jan 12;23(1):206-19. | ||||||||||
| Title: | NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. | ||||||||||
| Author: | Chen, Chia-Lin|Uthaya Kumar, Dinesh Babu|Punj, Vasu|Xu, Jun|Sher, Linda|Tahara, Stanley M|Hess, Sonja|Machida, Keigo | ||||||||||
| PMID: | 26724859 | ||||||||||
| 58. | |||||||||||
| Journal: | J Transl Med. 2016 Feb 12;14:49. | ||||||||||
| Title: | Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells. | ||||||||||
| Author: | Gehlot, Prashasnika|Shukla, Vivek|Gupta, Sanjay|Makidon, Paul E | ||||||||||
| PMID: | 26873175 | ||||||||||
| 59. | |||||||||||
| Journal: | Tumour Biol. 2016 Aug;37(8):10943-58. | ||||||||||
| Title: | Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity. | ||||||||||
| Author: | Peng, Yu-Chong|Lu, Shi-Dong|Zhong, Jian-Hong|Xie, Zhi-Bo|You, Xue-Mei|Peng, Ning-Fu|Li, Le-Qun | ||||||||||
| PMID: | 26886287 | ||||||||||
| 60. | |||||||||||
| Journal: | Sci Rep. 2016 Feb 18;6:21340. | ||||||||||
| Title: | Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1alpha activation. | ||||||||||
| Author: | Ambade, Aditya|Satishchandran, Abhishek|Szabo, Gyongyi | ||||||||||
| PMID: | 26888602 | ||||||||||
| 61. | |||||||||||
| Journal: | PLoS One. 2016 Feb 26;11(2):e0149897. | ||||||||||
| Title: | Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma. | ||||||||||
| Author: | Chang, Te-Sheng|Chen, Chi-Long|Wu, Yu-Chih|Liu, Jun-Jen|Kuo, Yung Che|Lee, Kam-Fai|Lin, Sin-Yi|Lin, Sey-En|Tung, Shui-Yi|Kuo, Liang-Mou|Tsai, Ying-Huang|Huang, Yen-Hua | ||||||||||
| PMID: | 26919045 | ||||||||||
| 62. | |||||||||||
| Journal: | Tumour Biol. 2016 Aug;37(8):11199-208. | ||||||||||
| Title: | Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK. | ||||||||||
| Author: | Shen, Chen|Ka, Sun-O|Kim, Su Jin|Kim, Ji Hye|Park, Byung-Hyun|Park, Ji Hyun | ||||||||||
| PMID: | 26939902 | ||||||||||
| 63. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 19;7(16):21644-57. | ||||||||||
| Title: | Hepatic cancer stem cell marker granulin-epithelin precursor and beta-catenin expression associate with recurrence in hepatocellular carcinoma. | ||||||||||
| Author: | Cheung, Phyllis F Y|Cheung, Tan To|Yip, Chi Wai|Ng, Linda W C|Fung, Sze Wai|Lo, Chung Mau|Fan, Sheung Tat|Cheung, Siu Tim | ||||||||||
| PMID: | 26942873 | ||||||||||
| 64. | |||||||||||
| Journal: | Cancer Lett. 2016 Jun 1;375(2):390-399. | ||||||||||
| Title: | Non-CSCs nourish CSCs through interleukin-17E-mediated activation of NF-kappaB and JAK/STAT3 signaling in human hepatocellular carcinoma. | ||||||||||
| Author: | Luo, Yongli|Yang, Zhi|Su, Li|Shan, Juanjuan|Xu, Huailong|Xu, Yanmin|Liu, Limei|Zhu, Wei|Chen, Xuejiao|Liu, Chungang|Chen, Jun|Yao, Chao|Cheng, Feifei|Zhang, Chengcheng|Ma, Qinghua|Shen, Junjie|Qian, Cheng | ||||||||||
| PMID: | 27000993 | ||||||||||
| 65. | |||||||||||
| Journal: | Oncotarget. 2016 May 31;7(22):32221-31. | ||||||||||
| Title: | Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells. | ||||||||||
| Author: | You, Yang|Zheng, Qiongdan|Dong, Yinying|Xie, Xiaoying|Wang, Yaohui|Wu, Sifan|Zhang, Lan|Wang, Yingcong|Xue, Tongchun|Wang, Zhiming|Chen, Rongxin|Wang, Yanhong|Cui, Jiefeng|Ren, Zhenggang | ||||||||||
| PMID: | 27050147 | ||||||||||
| 66. | |||||||||||
| Journal: | Oncoimmunology. 2015 Aug 31;5(3):e1086060. | ||||||||||
| Title: | Recognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cytokine-induced killer cells via NKG2d-ligands recognition. | ||||||||||
| Author: | Rong, Xiao-Xiang|Wei, Fang|Lin, Xiao-Lin|Qin, Yu-Juan|Chen, Lin|Wang, Hui-Yan|Shen, Hong-Fen|Jia, Li-Ting|Xie, Rao-Ying|Lin, Tao-Yan|Hao, Wei-Chao|Yang, Jie|Yang, Sheng|Cheng, Yu-Shuang|Huang, Wen-Hua|Li, Ai-Min|Sun, Yan|Luo, Rong-Cheng|Xiao, Dong | ||||||||||
| PMID: | 27141341 | ||||||||||
| 67. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G91-G104. | ||||||||||
| Title: | Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. | ||||||||||
| Author: | Sun, Lina|Beggs, Kevin|Borude, Prachi|Edwards, Genea|Bhushan, Bharat|Walesky, Chad|Roy, Nairita|Manley, Michael W Jr|Gunewardena, Sumedha|O'Neil, Maura|Li, Hua|Apte, Udayan | ||||||||||
| PMID: | 27151938 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 14;7(24):36814-36828. | ||||||||||
| Title: | Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma. | ||||||||||
| Author: | Jiang, Lupin|Shan, Juanjuan|Shen, Junjie|Wang, Yanzhou|Yan, Ping|Liu, Limei|Zhao, Wenxu|Xu, Yanmin|Zhu, Wei|Su, Li|Chen, Jun|Cheng, Feifei|Yao, Hong|Xu, Huicheng|Qian, Cheng|Liang, Zhiqing | ||||||||||
| PMID: | 27167111 | ||||||||||
| 69. | |||||||||||
| Journal: | J Hepatol. 2016 Nov;65(5):888-898. | ||||||||||
| Title: | EpCAM-regulated intramembrane proteolysis induces a cancer stem cell-like gene signature in hepatitis B virus-infected hepatocytes. | ||||||||||
| Author: | Mani, Saravana Kumar Kailasam|Zhang, Hao|Diab, Ahmed|Pascuzzi, Pete E|Lefrancois, Lydie|Fares, Nadim|Bancel, Brigitte|Merle, Philippe|Andrisani, Ourania | ||||||||||
| PMID: | 27238755 | ||||||||||
| 70. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):49194-49216. | ||||||||||
| Title: | Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease. | ||||||||||
| Author: | Simile, Maria M|Latte, Gavinella|Demartis, Maria I|Brozzetti, Stefania|Calvisi, Diego F|Porcu, Alberto|Feo, Claudio F|Seddaiu, Maria A|Daino, Lucia|Berasain, Carmen|Tomasi, Maria L|Avila, Matias A|Feo, Francesco|Pascale, Rosa M | ||||||||||
| PMID: | 27359056 | ||||||||||
| 71. | |||||||||||
| Journal: | Med Sci Monit. 2016 Aug 27;22:3025-34. | ||||||||||
| Title: | Effect of Over-Expression of Zinc-Finger Protein (ZFX) on Self-Renewal and Drug-Resistance of Hepatocellular Carcinoma. | ||||||||||
| Author: | Zhang, Shuhong|Shu, Ronghua|Yue, Meng|Zhang, Shuhong | ||||||||||
| PMID: | 27566731 | ||||||||||
| 72. | |||||||||||
| Journal: | Mol Med. 2016 Oct;22:653-663. | ||||||||||
| Title: | Stemness-related transcriptional factors and homing gene expression profiles in hepatic differentiation and cancer. | ||||||||||
| Author: | Toraih, Eman A|Fawzy, Manal S|El-Falouji, Abdullah I|Hamed, Elham O|Nemr, Nader A|Hussein, Mohammad H|Abd El Fadeal, Noha M | ||||||||||
| PMID: | 27623812 | ||||||||||
| 73. | |||||||||||
| Journal: | Cancer Res. 2016 Dec 1;76(23):7059-7071. | ||||||||||
| Title: | NRBP2 Overexpression Increases the Chemosensitivity of Hepatocellular Carcinoma Cells via Akt Signaling. | ||||||||||
| Author: | Zhang, Lixing|Ge, Chao|Zhao, Fangyu|Zhang, Yang|Wang, Xin|Yao, Ming|Li, Jinjun | ||||||||||
| PMID: | 27634758 | ||||||||||
| 74. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2016 Nov 11;35(1):176. | ||||||||||
| Title: | miR-589-5p inhibits MAP3K8 and suppresses CD90(+) cancer stem cells in hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Xi|Jiang, Peng|Shuai, Ling|Chen, Kai|Li, Zhonghu|Zhang, Yujun|Jiang, Yan|Li, Xiaowu | ||||||||||
| PMID: | 27835990 | ||||||||||
| 75. | |||||||||||
| Journal: | Cell Physiol Biochem. 2016;40(1-2):219-229. | ||||||||||
| Title: | The Emerging Roles of Long Noncoding RNA ROR (lincRNA-ROR) and its Possible Mechanisms in Human Cancers. | ||||||||||
| Author: | Pan, Yan|Li, Chen|Chen, Jing|Zhang, Kai|Chu, Xiaoyuan|Wang, Rui|Chen, Longbang | ||||||||||
| PMID: | 27855392 | ||||||||||
| 76. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Dec 15;22(24):6303. | ||||||||||
| Title: | Correction: Activation of IL6/IGFIR Confers Poor Prognosis of HBV-Related Hepatocellular Carcinoma through Induction of OCT4/NANOG Expression. | ||||||||||
| Author: | |||||||||||
| PMID: | 27980027 | ||||||||||
| 77. | |||||||||||
| Journal: | Sci Rep. 2017 Jan 13;7:40464. | ||||||||||
| Title: | Integrin beta4 promotes cell invasion and epithelial-mesenchymal transition through the modulation of Slug expression in hepatocellular carcinoma. | ||||||||||
| Author: | Li, Xiao-Long|Liu, Lin|Li, Dan-Dan|He, Ya-Ping|Guo, Le-Hang|Sun, Li-Ping|Liu, Lin-Na|Xu, Hui-Xiong|Zhang, Xiao-Ping | ||||||||||
| PMID: | 28084395 | ||||||||||
| 78. | |||||||||||
| Journal: | Sci Rep. 2017 Jan 30;7:41499. | ||||||||||
| Title: | CD133(+) cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Kai|Hao, Meijun|Ouyang, Yabo|Zheng, Jiasheng|Chen, Dexi | ||||||||||
| PMID: | 28134312 | ||||||||||
| 79. | |||||||||||
| Journal: | Cell Death Discov. 2017 Jan 23;3:16105. | ||||||||||
| Title: | Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer. | ||||||||||
| Author: | Wang, Pan|Wan, Wen-Wu|Xiong, Shuang-Long|Feng, Hua|Wu, Nan | ||||||||||
| PMID: | 28179999 | ||||||||||
| 80. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 4;8(14):23507-23516. | ||||||||||
| Title: | C-terminal truncated hepatitis B virus X protein regulates tumorigenicity, self-renewal and drug resistance via STAT3/Nanog signaling pathway. | ||||||||||
| Author: | Ching, Rachel Hiu Ha|Sze, Karen Man Fong|Lau, Eunice Yuen Ting|Chiu, Yung-Tuen|Lee, Joyce Man Fong|Ng, Irene Oi Lin|Lee, Terence Kin Wah | ||||||||||
| PMID: | 28186991 | ||||||||||
| 81. | |||||||||||
| Journal: | Cancer Lett. 2017 Aug 1;400:149-160. | ||||||||||
| Title: | Hepatitis B virus PreS1 facilitates hepatocellular carcinoma development by promoting appearance and self-renewal of liver cancer stem cells. | ||||||||||
| Author: | Liu, Zhixin|Dai, Xuechen|Wang, Tianci|Zhang, Chengcheng|Zhang, Wenjun|Zhang, Wei|Zhang, Qi|Wu, Kailang|Liu, Fang|Liu, Yingle|Wu, Jianguo | ||||||||||
| PMID: | 28455240 | ||||||||||
| 82. | |||||||||||
| Journal: | Life Sci. 2017 Jun 15;179:80-87. | ||||||||||
| Title: | Toll like receptor 4 and hepatocellular carcinoma; A systematic review. | ||||||||||
| Author: | Sepehri, Zahra|Kiani, Zohre|Kohan, Farhad|Alavian, Seyed Moayed|Ghavami, Saeid | ||||||||||
| PMID: | 28472619 | ||||||||||
| 83. | |||||||||||
| Journal: | Sci Rep. 2017 May 19;7(1):2164. | ||||||||||
| Title: | |||||||||||