Primary Site >> Colorectal Cancer

Gene >> MUC4

Journal: Cancer Res. 1992 Nov 1;52(21):5971-8.
Title: Mucin gene expression in colonic tissues and cell lines.
Author: Ogata, S|Uehara, H|Chen, A|Itzkowitz, S H
PMID: 1394223
Journal: J Pathol. 1995 Jun;176(2):143-9.
Title: Distribution of sialosyl Tn and Tn antigens within normal and malignant colorectal epithelium.
Author: Jass, J R|Allison, L J|Edgar, S G
PMID: 7636624
Journal: Glycoconj J. 1996 Oct;13(5):833-7.
Title: The transcripts of the apomucin genes MUC2, MUC4, and MUC5AC are large and appear as distinct bands.
Author: Baeckstrom, D|Hansson, G C
PMID: 8910010
Journal: Clin Cancer Res. 1998 Nov;4(11):2669-76.
Title: Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens.
Author: Zhang, S|Zhang, H S|Cordon-Cardo, C|Ragupathi, G|Livingston, P O
PMID: 9829729
Journal: Cancer Res. 1999 Aug 15;59(16):4083-9.
Title: Two novel mucin genes down-regulated in colorectal cancer identified by differential display.
Author: Williams, S J|McGuckin, M A|Gotley, D C|Eyre, H J|Sutherland, G R|Antalis, T M
PMID: 10463611
Journal: Biochem J. 2000 Jul 15;349(Pt 2):641-9.
Title: Cloning and characterization of the 5' flanking region of the sialomucin complex/rat Muc4 gene: promoter activity in cultured cells.
Author: Price-Schiavi, S A|Perez, A|Barco, R|Carraway, K L
PMID: 10880365
Journal: Cancer Immunol Immunother. 2001 Apr;50(2):109-14.
Title: Generation of human anti-MUC3 IgG antibodies after in vitro immunization of naive peripheral blood B-lymphocytes.
Author: Baritaki, S|Zafiropoulos, A|Georgopoulos, E|Souris, S|Krambovitis, E
PMID: 11401025
Journal: J Biol Chem. 2003 Aug 8;278(32):30142-7.
Title: Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
Author: Ramsauer, Victoria P|Carraway, Coralie A Carothers|Salas, Pedro J I|Carraway, Kermit L
PMID: 12748185
Journal: Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):77-99.
Title: Mucins and mucin binding proteins in colorectal cancer.
Author: Byrd, James C|Bresalier, Robert S
PMID: 15000151
Journal: Biol Cell. 2004 Mar;96(2):145-51.
Title: Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate.
Author: Leteurtre, Emmanuelle|Gouyer, Valerie|Rousseau, Karine|Moreau, Odile|Barbat, Alain|Swallow, Dallas|Huet, Guillemette|Lesuffleur, Thecla
PMID: 15050369
Journal: Int J Oncol. 2004 Oct;25(4):1119-26.
Title: Expression of the cell surface mucin gene family in adenocarcinomas.
Author: Packer, Leisl M|Williams, Stephanie J|Callaghan, Shirley|Gotley, David C|McGuckin, Michael A
PMID: 15375564
Journal: Br J Cancer. 2009 Jan 27;100(2):344-51.
Title: Promoter CpG methylation in cancer cells contributes to the regulation of MUC4.
Author: Yamada, N|Nishida, Y|Tsutsumida, H|Goto, M|Higashi, M|Nomoto, M|Yonezawa, S
PMID: 19127263
Journal: Int J Cancer. 2011 Apr 15;128(8):1860-71.
Title: Seromic profiling of colorectal cancer patients with novel glycopeptide microarray.
Author: Pedersen, Johannes W|Blixt, Ola|Bennett, Eric P|Tarp, Mads A|Dar, Imran|Mandel, Ulla|Poulsen, Steen S|Pedersen, Anders E|Rasmussen, Susanne|Jess, Per|Clausen, Henrik|Wandall, Hans H
PMID: 21344374
Journal: Expert Rev Proteomics. 2011 Aug;8(4):435-7.
Title: Glycopeptide microarray for autoantibody detection in cancer.
Author: Reis, Celso A|Campos, Diana|Osorio, Hugo|Santos, Lucio Lara
PMID: 21819298
Journal: BMC Med Genet. 2013 Mar 8;14:32.
Title: Mutation spectrum in human colorectal cancers and potential functional relevance.
Author: Yin, Hongzhuan|Liang, Yichao|Yan, Zhaopeng|Liu, Baolin|Su, Qi
PMID: 23497483
Journal: Cancer Sci. 2013 Jul;104(7):958-64.
Title: Transmembrane mucin MUC1 overexpression and its association with CD10(+) myeloid cells, transforming growth factor-beta1 expression, and tumor budding grade in colorectal cancer.
Author: Khanh, Do Trong|Mekata, Eiji|Mukaisho, Ken-ichi|Sugihara, Hiroyuki|Shimizu, Tomoharu|Shiomi, Hisanori|Murata, Satoshi|Naka, Shigeyuki|Yamamoto, Hiroshi|Endo, Yoshihiro|Tani, Tohru
PMID: 23566254
Journal: Cell Oncol (Dordr). 2013 Apr;36(2):155-67.
Title: Epigenetic control of HNF-4alpha in colon carcinoma cells affects MUC4 expression and malignancy.
Author: Algamas-Dimantov, Anna|Yehuda-Shnaidman, Einav|Peri, Irena|Schwartz, Betty
PMID: 23307400
Journal: Int J Cancer. 2014 May 1;134(9):2180-88.
Title: Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening.
Author: Pedersen, Johannes W|Gentry-Maharaj, Aleksandra|Nostdal, Alexander|Fourkala, Evangelia-Ourania|Dawnay, Anne|Burnell, Matthew|Zaikin, Alexey|Burchell, Joy|Papadimitriou, Joyce Taylor|Clausen, Henrik|Jacobs, Ian|Menon, Usha|Wandall, Hans H
PMID: 24122770
Journal: Arch Pathol Lab Med. 2014 Aug;138(8):1015-26.
Title: Cadherin-17 and SATB2 are sensitive and specific immunomarkers for medullary carcinoma of the large intestine.
Author: Lin, Fan|Shi, Jianhui|Zhu, Shaobo|Chen, Zongming|Li, Aihua|Chen, Taiying|Wang, Hanlin L|Liu, Haiyan
PMID: 24437456
Journal: Asian Pac J Cancer Prev. 2014;15(15):6269-73.
Title: MiR-150-5p suppresses colorectal cancer cell migration and invasion through targeting MUC4.
Author: Wang, Wei-Hua|Chen, Jie|Zhao, Feng|Zhang, Bu-Rong|Yu, Hong-Sheng|Jin, Hai-Ying|Dai, Jin-Hua
PMID: 25124610
Journal: PLoS One. 2014 Oct 8;9(10):e109600.
Title: REG4 independently predicts better prognosis in non-mucinous colorectal cancer.
Author: Kaprio, Tuomas|Hagstrom, Jaana|Mustonen, Harri|Koskensalo, Selja|Andersson, Leif C|Haglund, Caj
PMID: 25295732
Journal: PLoS One. 2014 Dec 31;9(12):e115613.
Title: A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor.
Author: Shibahara, Hiroaki|Higashi, Michiyo|Yokoyama, Seiya|Rousseau, Karine|Kitazono, Iwao|Osako, Masahiko|Shirahama, Hiroshi|Tashiro, Yukie|Kurumiya, Yasuhiro|Narita, Michihiko|Kuze, Shingo|Hasagawa, Hiroshi|Kato, Takehito|Kubota, Hitoshi|Suzuki, Hideaki|Arai,
PMID: 25551773
Journal: Int J Cancer. 2015 Jun 15;136(12):2811-21.
Title: MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer.
Author: Renaud, Florence|Vincent, Audrey|Mariette, Christophe|Crepin, Michel|Stechly, Laurence|Truant, Stephanie|Copin, Marie-Christine|Porchet, Nicole|Leteurtre, Emmanuelle|Van Seuningen, Isabelle|Buisine, Marie-Pierre
PMID: 25403854
Journal: Int J Clin Exp Med. 2015 Jul 15;8(7):10274-83. eCollection 2015.
Title: Clinicopathological and prognostic significance of MUC4 expression in cancers: evidence from meta-analysis.
Author: Huang, Xing|Wang, Xin|Lu, Shi-Ming|Chen, Chen|Wang, Jie|Zheng, Yan-Yan|Ren, Bin-Hui|Xu, Lin
PMID: 26379819
Journal: Oncogene. 2016 May 19;35(20):2645-54.
Title: Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.
Author: Das, S|Rachagani, S|Sheinin, Y|Smith, L M|Gurumurthy, C B|Roy, H K|Batra, S K
PMID: 26364605
Journal: Cancer Lett. 2016 May 1;374(2):304-14.
Title: Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.
Author: Krishn, Shiv Ram|Kaur, Sukhwinder|Smith, Lynette M|Johansson, Sonny L|Jain, Maneesh|Patel, Asish|Gautam, Shailendra K|Hollingsworth, Michael A|Mandel, Ulla|Clausen, Henrik|Lo, Wing-Cheong|Fan, Wai-Tong Louis|Manne, Upender|Batra, Surinder K
PMID: 26898938
Journal: Genes Cancer. 2016 May;7(5-6):154-168.
Title: MUC4 is negatively regulated through the Wnt/beta-catenin pathway via the Notch effector Hath1 in colorectal cancer.
Author: Pai, Priya|Rachagani, Satyanarayana|Dhawan, Punita|Sheinin, Yuri M|Macha, Muzafar A|Qazi, Asif Khurshid|Chugh, Seema|Ponnusamy, Moorthy P|Mallya, Kavita|Pothuraju, Ramesh|Batra, Surinder K
PMID: 27551331
Journal: Oncotarget. 2017 Jan 24;8(4):7025-7038.
Title: Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance.
Author: Krishn, Shiv Ram|Kaur, Sukhwinder|Sheinin, Yuri M|Smith, Lynette M|Gautam, Shailendra K|Patel, Asish|Jain, Maneesh|Juvvigunta, Vasthala|Pai, Priya|Lazenby, Audrey J|Roy, Hemant K|Batra, Surinder K
PMID: 27705923
Journal: Oncotarget. 2017 May 17;8(40):67152-67168.
Title: Genomic alterations in mucins across cancers.
Author: King, Ryan J|Yu, Fang|Singh, Pankaj K
PMID: 28978023
Journal: J Clin Gastroenterol. 2018 May 18.
Title: Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis.
Author: Niv, Yaron|Rokkas, Theodore
PMID: 29782466
Journal: J Transl Med. 2018 Sep 20;16(1):259.
Title: Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.
Author: Jonckheere, Nicolas|Van Seuningen, Isabelle
PMID: 30236127