Primary Site >> Colorectal Cancer

Gene >> MUC4

  • 1992
  • 1995
  • 1996
  • 1998
  • 1999
  • 2000
  • 2001
  • 2003
  • 2004
  • 2009
  • 2011
  • 2013
  • 2014
  • 2015
  • 2016
  • 2017
  • 2018
Ref: Mucin gene expression in colonic tissues and cell lines.
PMID: 1394223
 Ref: Distribution of sialosyl Tn and Tn antigens within normal and malignant colorectal epithelium.
PMID: 7636624
 Ref: The transcripts of the apomucin genes MUC2, MUC4, and MUC5AC are large and appear as distinct bands.
PMID: 8910010
 Ref: Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens.
PMID: 9829729
 Ref: Two novel mucin genes down-regulated in colorectal cancer identified by differential display.
PMID: 10463611
 Ref: Cloning and characterization of the 5' flanking region of the sialomucin complex/rat Muc4 gene: promoter activity in cultured cells.
PMID: 10880365
 Ref: Generation of human anti-MUC3 IgG antibodies after in vitro immunization of naive peripheral blood B-lymphocytes.
PMID: 11401025
 Ref: Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
PMID: 12748185
 Ref: Mucins and mucin binding proteins in colorectal cancer.
PMID: 15000151
Ref: Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate.
PMID: 15050369
Ref: Expression of the cell surface mucin gene family in adenocarcinomas.
PMID: 15375564
 Ref: Promoter CpG methylation in cancer cells contributes to the regulation of MUC4.
PMID: 19127263
 Ref: Seromic profiling of colorectal cancer patients with novel glycopeptide microarray.
PMID: 21344374
Ref: Glycopeptide microarray for autoantibody detection in cancer.
PMID: 21819298
 Ref: Epigenetic control of HNF-4alpha in colon carcinoma cells affects MUC4 expression and malignancy.
PMID: 23307400
Ref: Mutation spectrum in human colorectal cancers and potential functional relevance.
PMID: 23497483
Ref: Transmembrane mucin MUC1 overexpression and its association with CD10(+) myeloid cells, transforming growth factor-beta1 expression, and tumor budding grade in colorectal cancer.
PMID: 23566254
 Ref: Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening.
PMID: 24122770
Ref: Cadherin-17 and SATB2 are sensitive and specific immunomarkers for medullary carcinoma of the large intestine.
PMID: 24437456
Ref: MiR-150-5p suppresses colorectal cancer cell migration and invasion through targeting MUC4.
PMID: 25124610
Ref: REG4 independently predicts better prognosis in non-mucinous colorectal cancer.
PMID: 25295732
Ref: A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor.
PMID: 25551773
 Ref: MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer.
PMID: 25403854
Ref: Clinicopathological and prognostic significance of MUC4 expression in cancers: evidence from meta-analysis.
PMID: 26379819
 Ref: Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.
PMID: 26364605
Ref: Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.
PMID: 26898938
Ref: MUC4 is negatively regulated through the Wnt/beta-catenin pathway via the Notch effector Hath1 in colorectal cancer.
PMID: 27551331
 Ref: Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance.
PMID: 27705923
Ref: Genomic alterations in mucins across cancers.
PMID: 28978023
 Ref: Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis.
PMID: 29782466
Ref: Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.
PMID: 30236127