Primary Site >> Stomach Cancer
Gene >> MTOR
| 1. | |||||||||||
| Journal: | Bioorg Med Chem. 2006 Aug 1;14(15):5351-6. | ||||||||||
| Title: | The synthesis and anti-proliferative effects of beta-elemene derivatives with mTOR inhibition activity. | ||||||||||
| Author: | Xu, Liying|Tao, Shujuan|Wang, Xianming|Yu, Zhiying|Wang, Minwei|Chen, Duo|Jing, Yongkui|Dong, Jinhua | ||||||||||
| PMID: | 16617020 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Cancer. 2007 Apr 15;120(8):1803-10. | ||||||||||
| Title: | Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model. | ||||||||||
| Author: | Lang, Sven A|Gaumann, Andreas|Koehl, Gudrun E|Seidel, Ulrike|Bataille, Frauke|Klein, Dagmar|Ellis, Lee M|Bolder, Ulrich|Hofstaedter, Ferdinand|Schlitt, Hans-Jurgen|Geissler, Edward K|Stoeltzing, Oliver | ||||||||||
| PMID: | 17230506 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 May;6(5):686-90. Epub 2007 Feb 3. | ||||||||||
| Title: | Defibrotide: an endothelium protecting and stabilizing drug, has an anti-angiogenic potential in vitro and in vivo. | ||||||||||
| Author: | Koehl, Gudrun E|Geissler, Edward K|Iacobelli, Massimo|Frei, Caroline|Burger, Verena|Haffner, Silvia|Holler, Ernst|Andreesen, Reinhard|Schlitt, Hans J|Eissner, Gunther | ||||||||||
| PMID: | 17495522 | ||||||||||
| 4. | |||||||||||
| Journal: | Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Aug;24(4):387-91. | ||||||||||
| Title: | [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines]. | ||||||||||
| Author: | Sun, Dan-feng|Fang, Jing-yuan|Zhang, Yan-jie|Tian, Xiao-qing|Zhu, Hong-yin|Li, En-ling|Gu, Wei-qi|Shen, Guan-feng | ||||||||||
| PMID: | 17680526 | ||||||||||
| 5. | |||||||||||
| Journal: | Planta Med. 2007 Sep;73(11):1176-81. Epub 2007 Sep 7. | ||||||||||
| Title: | Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells. | ||||||||||
| Author: | Jiang, Tiejun|Zhu, Yongliang|Luo, Cong|Lu, Xiaoyong|Zhang, Wo|Qiu, Fuming|Huang, Jian | ||||||||||
| PMID: | 17823871 | ||||||||||
| 6. | |||||||||||
| Journal: | Carcinogenesis. 2008 Apr;29(4):704-12. | ||||||||||
| Title: | Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. | ||||||||||
| Author: | Kim, Kwang-Kyu|Lee, Jung Joon|Yang, Young|You, Kwan-Hee|Lee, Jeong-Hyung | ||||||||||
| PMID: | 18258606 | ||||||||||
| 7. | |||||||||||
| Journal: | Eur J Cancer. 2008 May;44(7):1022-9. | ||||||||||
| Title: | Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. | ||||||||||
| Author: | Hashimoto, Isaya|Koizumi, Keiichi|Tatematsu, Mikiko|Minami, Takayuki|Cho, Seiji|Takeno, Nobuhiro|Nakashima, Akitoshi|Sakurai, Hiroaki|Saito, Shigeru|Tsukada, Kazuhiro|Saiki, Ikuo | ||||||||||
| PMID: | 18375114 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2008 Jun 6;283(23):15807-15. | ||||||||||
| Title: | Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion. | ||||||||||
| Author: | Lin, Ming-Tsan|Kuo, I-Hsin|Chang, Cheng-Chi|Chu, Chia-Yu|Chen, Hsing-Yu|Lin, Been-Ren|Sureshbabu, Munisamy|Shih, Hou-Jung|Kuo, Min-Liang | ||||||||||
| PMID: | 18381294 | ||||||||||
| 9. | |||||||||||
| Journal: | Sci China C Life Sci. 2008 Jul;51(7):640-7. | ||||||||||
| Title: | Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines. | ||||||||||
| Author: | Sun, Danfeng|Toan, Xiaoqing|Zhang, Yanjie|Chen, Yingxuan|Lu, Rong|Wang, Xia|Fang, Jingyuan | ||||||||||
| PMID: | 18622747 | ||||||||||
| 10. | |||||||||||
| Journal: | Anticancer Res. 2008 Nov-Dec;28(6A):3801-8. | ||||||||||
| Title: | mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo. | ||||||||||
| Author: | Cejka, Daniel|Preusser, Matthias|Fuereder, Thorsten|Sieghart, Wolfgang|Werzowa, Johannes|Strommer, Sabine|Wacheck, Volker | ||||||||||
| PMID: | 19189667 | ||||||||||
| 11. | |||||||||||
| Journal: | Endocr Relat Cancer. 2009 Jun;16(2):599-611. | ||||||||||
| Title: | Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation. | ||||||||||
| Author: | Alvarez, Carlos J P|Lodeiro, Maria|Theodoropoulou, Marily|Camina, Jesus P|Casanueva, Felipe F|Pazos, Yolanda | ||||||||||
| PMID: | 19153210 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Mar 1;15(5):1821-9. | ||||||||||
| Title: | Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer. | ||||||||||
| Author: | Yu, Guanzhen|Wang, Jiejun|Chen, Ying|Wang, Xi|Pan, Jun|Li, Gang|Jia, Zhiliang|Li, Qiang|Yao, James C|Xie, Keping | ||||||||||
| PMID: | 19223493 | ||||||||||
| 13. | |||||||||||
| Journal: | Br J Cancer. 2009 Mar 10;100(5):782-8. | ||||||||||
| Title: | Relation between outcomes and localisation of p-mTOR expression in gastric cancer. | ||||||||||
| Author: | Murayama, T|Inokuchi, M|Takagi, Y|Yamada, H|Kojima, K|Kumagai, J|Kawano, T|Sugihara, K | ||||||||||
| PMID: | 19223902 | ||||||||||
| 14. | |||||||||||
| Journal: | Int J Oncol. 2009 May;34(5):1231-40. | ||||||||||
| Title: | Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo. | ||||||||||
| Author: | Mishra, Roshan|Miyamoto, Masaki|Yoshioka, Tatsuya|Ishikawa, Keidai|Matsumura, Yoshiyuki|Shoji, Yasuhito|Ichinokawa, Kazuomi|Itoh, Tommo|Shichinohe, Toshiaki|Hirano, Satoshi|Kondo, Satoshi | ||||||||||
| PMID: | 19360336 | ||||||||||
| 15. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66. | ||||||||||
| Title: | Gastric cancer in the era of molecularly targeted agents: current drug development strategies. | ||||||||||
| Author: | Arkenau, Hendrik-Tobias | ||||||||||
| PMID: | 19363621 | ||||||||||
| 16. | |||||||||||
| Journal: | Transplant Proc. 2009 Apr;41(3):959-61. | ||||||||||
| Title: | Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report. | ||||||||||
| Author: | Lasmar, E P|Coelho, L G V|Lasmar, M F|Lasmar, L F|Lima, P V|Nogueira, A F | ||||||||||
| PMID: | 19376398 | ||||||||||
| 17. | |||||||||||
| Journal: | Br J Cancer. 2009 Jun 2;100(11):1739-45. | ||||||||||
| Title: | FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo. | ||||||||||
| Author: | Cejka, D|Kuntner, C|Preusser, M|Fritzer-Szekeres, M|Fueger, B J|Strommer, S|Werzowa, J|Fuereder, T|Wanek, T|Zsebedics, M|Mueller, M|Langer, O|Wacheck, V | ||||||||||
| PMID: | 19436299 | ||||||||||
| 18. | |||||||||||
| Journal: | Expert Opin Investig Drugs. 2009 Jul;18(7):945-55. | ||||||||||
| Title: | Novel investigational drugs for gastric cancer. | ||||||||||
| Author: | Vecchione, Loredana|Orditura, Michele|Ciardiello, Fortunato|De Vita, Ferdinando | ||||||||||
| PMID: | 19466878 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2009 Sep 15;69(18):7160-4. | ||||||||||
| Title: | mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. | ||||||||||
| Author: | Matsumoto, Kazuko|Arao, Tokuzo|Tanaka, Kaoru|Kaneda, Hiroyasu|Kudo, Kanae|Fujita, Yoshihiko|Tamura, Daisuke|Aomatsu, Keiichi|Tamura, Tomohide|Yamada, Yasuhide|Saijo, Nagahiro|Nishio, Kazuto | ||||||||||
| PMID: | 19738050 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Sci. 2009 Dec;100(12):2402-10. | ||||||||||
| Title: | Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer. | ||||||||||
| Author: | Matsuzaki, Taro|Yashiro, Masakazu|Kaizaki, Ryoji|Yasuda, Koichi|Doi, Yosuke|Sawada, Tetsuji|Ohira, Masaichi|Hirakawa, Kosei | ||||||||||
| PMID: | 19764996 | ||||||||||
| 21. | |||||||||||
| Journal: | J Hematol Oncol. 2009 Oct 27;2:45. | ||||||||||
| Title: | Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy. | ||||||||||
| Author: | Yuan, Ruirong|Kay, Andrea|Berg, William J|Lebwohl, David | ||||||||||
| PMID: | 19860903 | ||||||||||
| 22. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2009 Dec 13;28:152. | ||||||||||
| Title: | The role of mTOR and phospho-p70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarray. | ||||||||||
| Author: | Xiao, Li|Wang, Yi C|Li, Wu S|Du, Yan | ||||||||||
| PMID: | 20003385 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Cancer. 2010 Jun 15;126(12):2904-13. | ||||||||||
| Title: | Prognostic role of p-mTOR expression in cancer tissues and metastatic lymph nodes in pT2b gastric cancer. | ||||||||||
| Author: | An, Ji Yeong|Kim, Kyoung Mee|Choi, Min Gew|Noh, Jae Hyung|Sohn, Tae Sung|Bae, Jae Moon|Kim, Sung | ||||||||||
| PMID: | 19739122 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2010 Jun 1;126(11):2716-25. | ||||||||||
| Title: | Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells. | ||||||||||
| Author: | Shigematsu, Hideo|Yoshida, Kazuhiro|Sanada, Yuichi|Osada, Shinnji|Takahashi, Takao|Wada, Yoshiyuki|Konishi, Kazuo|Okada, Morihito|Fukushima, Masakazu | ||||||||||
| PMID: | 19856312 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Treat Rev. 2010 May;36(3):235-48. | ||||||||||
| Title: | Esophagogastric cancer: targeted agents. | ||||||||||
| Author: | Ku, Geoffrey Y|Ilson, David H | ||||||||||
| PMID: | 20122806 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Biol Ther. 2010 Jun 1;9(11):919-27. Epub 2010 Jun 18. | ||||||||||
| Title: | Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo. | ||||||||||
| Author: | Jaeger-Lansky, Agnes|Cejka, Daniel|Ying, Liu|Preusser, Matthias|Hoeflmayer, Doris|Fuereder, Thorsten|Koehrer, Stefan|Wacheck, Volker | ||||||||||
| PMID: | 20404549 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer Lett. 2010 Oct 28;296(2):249-56. | ||||||||||
| Title: | mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo. | ||||||||||
| Author: | Fuereder, Thorsten|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Preusser, Matthias|Strommer, Sabine|Cejka, Daniel|Koehrer, Stefan|Crevenna, Richard|Wacheck, Volker | ||||||||||
| PMID: | 20471160 | ||||||||||
| 28. | |||||||||||
| Journal: | Phytother Res. 2010 Dec;24(12):1857-61. | ||||||||||
| Title: | Activation of AMP-activated protein kinase on human gastric cancer cells by apoptosis induced by corosolic acid isolated from Weigela subsessilis. | ||||||||||
| Author: | Lee, Myung Sun|Lee, Chang Min|Cha, Eun Young|Thuong, Phuong Thien|Bae, KiHwan|Song, In Sang|Noh, Seung Moo|Sul, Ji Young | ||||||||||
| PMID: | 20564492 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Lett. 2010 Dec 18;299(1):22-8. | ||||||||||
| Title: | RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase. | ||||||||||
| Author: | Lee, Kyung-Hun|Hur, Hyung-Seok|Im, Seock-Ah|Lee, Juhee|Kim, Hwang-Phill|Yoon, Young-Kwang|Han, Sae-Won|Song, Sang-Hyun|Oh, Do-Youn|Kim, Tae-You|Bang, Yung-Jue | ||||||||||
| PMID: | 20727673 | ||||||||||
| 30. | |||||||||||
| Journal: | BMC Cancer. 2010 Oct 7;10:536. | ||||||||||
| Title: | Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer. | ||||||||||
| Author: | Xu, Da-zhi|Geng, Qi-rong|Tian, Ying|Cai, Mu-yan|Fang, Xin-juan|Zhan, You-qing|Zhou, Zhi-wei|Li, Wei|Chen, Ying-bo|Sun, Xiao-wei|Guan, Yuan-xiang|Li, Yuan-fang|Lin, Tong-yu | ||||||||||
| PMID: | 20929525 | ||||||||||
| 31. | |||||||||||
| Journal: | Invest New Drugs. 2011 Dec;29(6):1198-205. | ||||||||||
| Title: | Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination. | ||||||||||
| Author: | Taguchi, Fumiko|Kodera, Yasuo|Katanasaka, Yasufumi|Yanagihara, Kazuyoshi|Tamura, Tomohide|Koizumi, Fumiaki | ||||||||||
| PMID: | 20532589 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8. | ||||||||||
| Title: | Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. | ||||||||||
| Author: | Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin | ||||||||||
| PMID: | 21286718 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Nutr Food Res. 2011 May;55(5):749-60. | ||||||||||
| Title: | Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. | ||||||||||
| Author: | Xing, Xin|Wang, Juan|Xing, Ling Xiao|Li, Yue Hong|Yan, Xia|Zhang, Xiang Hong | ||||||||||
| PMID: | 21287681 | ||||||||||
| 34. | |||||||||||
| Journal: | PLoS One. 2011 Feb 18;6(2):e16694. | ||||||||||
| Title: | A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. | ||||||||||
| Author: | Kim, Hark Kyun|Choi, Il Ju|Kim, Chan Gyoo|Kim, Hee Sung|Oshima, Akira|Michalowski, Aleksandra|Green, Jeffrey E | ||||||||||
| PMID: | 21364753 | ||||||||||
| 35. | |||||||||||
| Journal: | BMC Cancer. 2011 May 20;11:183. | ||||||||||
| Title: | beta-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis. | ||||||||||
| Author: | Liu, Jing|Zhang, Ye|Qu, Jinglei|Xu, Ling|Hou, Kezuo|Zhang, Jingdong|Qu, Xiujuan|Liu, Yunpeng | ||||||||||
| PMID: | 21595977 | ||||||||||
| 36. | |||||||||||
| Journal: | Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1. | ||||||||||
| Title: | Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling. | ||||||||||
| Author: | Wang, Kui|Liu, Rui|Li, Jingyi|Mao, Jiali|Lei, Yunlong|Wu, Jinhua|Zeng, Jun|Zhang, Tao|Wu, Hong|Chen, Lijuan|Huang, Canhua|Wei, Yuquan | ||||||||||
| PMID: | 21610320 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Treat Rev. 2011 Dec;37(8):599-610. | ||||||||||
| Title: | Molecularly targeted therapies in unresectable-metastatic gastric cancer: a systematic review. | ||||||||||
| Author: | Zagouri, Flora|Papadimitriou, Christos A|Dimopoulos, Meletios-Athanassios|Pectasides, Dimitrios | ||||||||||
| PMID: | 21676549 | ||||||||||
| 38. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Aug 15;17(16):5322-32. | ||||||||||
| Title: | Gastric cancer growth control by BEZ235 in vivo does not correlate with PI3K/mTOR target inhibition but with [18F]FLT uptake. | ||||||||||
| Author: | Fuereder, Thorsten|Wanek, Thomas|Pflegerl, Pamina|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Strommer, Sabine|Kuntner, Claudia|Wrba, Friedrich|Werzowa, Johannes|Hejna, Michael|Muller, Markus|Langer, Oliver|Wacheck, Volker | ||||||||||
| PMID: | 21712451 | ||||||||||
| 39. | |||||||||||
| Journal: | Chin J Cancer. 2011 Jul;30(7):490-6. | ||||||||||
| Title: | Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells. | ||||||||||
| Author: | Xu, Ling|Qu, Xiu-Juan|Liu, Yun-Peng|Xu, Ying-Ying|Liu, Jing|Hou, Ke-Zuo|Zhang, Ye | ||||||||||
| PMID: | 21718595 | ||||||||||
| 40. | |||||||||||
| Journal: | Hepatogastroenterology. 2011 May-Jun;58(107-108):1075-80. | ||||||||||
| Title: | Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin. | ||||||||||
| Author: | Yao, Chun|Liu, Jinxiu|Shao, Liwei | ||||||||||
| PMID: | 21830446 | ||||||||||
| 41. | |||||||||||
| Journal: | Anticancer Res. 2011 Oct;31(10):3353-60. | ||||||||||
| Title: | ERas enhances resistance to CPT-11 in gastric cancer. | ||||||||||
| Author: | Kubota, Eiji|Kataoka, Hiromi|Tanaka, Mamoru|Okamoto, Yasuyuki|Ebi, Masahide|Hirata, Yoshikazu|Murakami, Kenji|Mizoshita, Tsutomu|Shimura, Takaya|Mori, Yoshinori|Tanida, Satoshi|Kamiya, Takeshi|Aoyama, Mineyoshi|Asai, Kiyofumi|Joh, Takashi | ||||||||||
| PMID: | 21965746 | ||||||||||
| 42. | |||||||||||
| Journal: | Exp Ther Med. 2011 Mar;2(2):251-256. | ||||||||||
| Title: | Prognostic value of co-expression of STAT3, mTOR and EGFR in gastric cancer. | ||||||||||
| Author: | Inokuchi, Mikito|Murayama, Tadao|Hayashi, Mikiko|Takagi, Yoko|Kato, Keiji|Enjoji, Megumu|Kojima, Kazuyuki|Kumagai, Jiro|Sugihara, Kenichi | ||||||||||
| PMID: | 22977493 | ||||||||||
| 43. | |||||||||||
| Journal: | Int J Cancer. 2012 Feb 1;130(3):491-6. | ||||||||||
| Title: | mTOR as a therapeutic target in patients with gastric cancer. | ||||||||||
| Author: | Al-Batran, Salah-Eddin|Ducreux, Michel|Ohtsu, Atsushi | ||||||||||
| PMID: | 21898386 | ||||||||||
| 44. | |||||||||||
| Journal: | Surg Today. 2012 Apr;42(4):313-27. | ||||||||||
| Title: | Molecular targeted agents for gastric and gastroesophageal junction cancer. | ||||||||||
| Author: | Oshima, Takashi|Masuda, Munetaka | ||||||||||
| PMID: | 22127535 | ||||||||||
| 45. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Feb;11(2):439-51. | ||||||||||
| Title: | Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer. | ||||||||||
| Author: | Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue | ||||||||||
| PMID: | 22135232 | ||||||||||
| 46. | |||||||||||
| Journal: | Int J Oncol. 2012 Apr;40(4):1259-66. | ||||||||||
| Title: | NVP-BKM120, a novel PI3K inhibitor, shows synergism with a STAT3 inhibitor in human gastric cancer cells harboring KRAS mutations. | ||||||||||
| Author: | Park, Eunju|Park, Jinah|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue | ||||||||||
| PMID: | 22159814 | ||||||||||
| 47. | |||||||||||
| Journal: | Front Biosci (Schol Ed). 2012 Jan 1;4:269-76. | ||||||||||
| Title: | Therapeutics target of CXCR4 and its downstream in peritoneal carcinomatosis of gastric cancer. | ||||||||||
| Author: | Koizumi, Keiichi|Kato, Shinichiro|Sakurai, Hiroaki|Hashimoto, Isaya|Yasumoto, Kazuo|Saiki, Ikuo | ||||||||||
| PMID: | 22202059 | ||||||||||
| 48. | |||||||||||
| Journal: | Toxicol Lett. 2012 Apr 5;210(1):78-86. | ||||||||||
| Title: | E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells. | ||||||||||
| Author: | Hu, Chen|Zou, Mei-Juan|Zhao, Li|Lu, Na|Sun, Ya-Jing|Gou, Shao-Hua|Xi, Tao|Guo, Qing-Long | ||||||||||
| PMID: | 22322152 | ||||||||||
| 49. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Jan 1;13(1):34-42. | ||||||||||
| Title: | Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells. | ||||||||||
| Author: | Bhattacharya, Bhaskar|Akram, Mohamed|Balasubramanian, Indirikumar|Tam, Kimberley K Y|Koh, King X|Yee, Mei Q|Soong, Richie | ||||||||||
| PMID: | 22336586 | ||||||||||
| 50. | |||||||||||
| Journal: | J Biol Chem. 2012 Apr 6;287(15):12132-41. | ||||||||||
| Title: | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells. | ||||||||||
| Author: | Chen, Guang|Chen, Si-Meng|Wang, Xiang|Ding, Xiao-Fei|Ding, Jian|Meng, Ling-Hua | ||||||||||
| PMID: | 22337890 | ||||||||||
| 51. | |||||||||||
| Journal: | Cell Cycle. 2012 Apr 1;11(7):1414-31. | ||||||||||
| Title: | The roles of REIC gene and its encoding product in gastric carcinoma. | ||||||||||
| Author: | Xu, Xiao-yan|Xia, Pu|Yu, Miao|Nie, Xiao-cui|Yang, Xue|Xing, Ya-nan|Liu, Yun-peng|Takano, Yasuo|Zheng, Hua-chuan | ||||||||||
| PMID: | 22421143 | ||||||||||
| 52. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15. | ||||||||||
| Title: | Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines. | ||||||||||
| Author: | Mueller, Annett|Bachmann, Erika|Linnig, Monika|Khillimberger, Katrin|Schimanski, Carl Christoph|Galle, Peter R|Moehler, Markus | ||||||||||
| PMID: | 22543857 | ||||||||||
| 53. | |||||||||||
| Journal: | Int J Oncol. 2012 Aug;41(2):551-8. | ||||||||||
| Title: | Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification. | ||||||||||
| Author: | Tomioka, Hideo|Mukohara, Toru|Kataoka, Yu|Ekyalongo, Roudy Chiminch|Funakoshi, Yohei|Imai, Yasuo|Kiyota, Naomi|Fujiwara, Yutaka|Minami, Hironobu | ||||||||||
| PMID: | 22614071 | ||||||||||
| 54. | |||||||||||
| Journal: | J Hematol Oncol. 2012 Jun 18;5:31. | ||||||||||
| Title: | Novel targeted agents for gastric cancer. | ||||||||||
| Author: | Liu, Lian|Wu, Ning|Li, Jin | ||||||||||
| PMID: | 22709792 | ||||||||||
| 55. | |||||||||||
| Journal: | PLoS One. 2012;7(7):e40037. | ||||||||||
| Title: | Identification of hsa-miR-335 as a prognostic signature in gastric cancer. | ||||||||||
| Author: | Yan, Zhi|Xiong, Yimin|Xu, Weitian|Gao, Juan|Cheng, Yi|Wang, Zhigang|Chen, Fang|Zheng, Guorong | ||||||||||
| PMID: | 22802949 | ||||||||||
| 56. | |||||||||||
| Journal: | Biologics. 2012;6:137-46. | ||||||||||
| Title: | Metastatic gastric cancer - focus on targeted therapies. | ||||||||||
| Author: | Meza-Junco, Judith|Sawyer, Michael B | ||||||||||
| PMID: | 22807624 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncol Lett. 2012 Dec;4(6):1213-1218. | ||||||||||
| Title: | Immunohistochemical expression of mTOR negatively correlates with PTEN expression in gastric carcinoma. | ||||||||||
| Author: | Li, Min|Sun, Huawen|Song, Lujun|Gao, Xiaodong|Chang, Wenju|Qin, Xinyu | ||||||||||
| PMID: | 23205120 | ||||||||||
| 58. | |||||||||||
| Journal: | Integr Cancer Ther. 2013 Mar;12(2):165-73. | ||||||||||
| Title: | Lactobacillus casei extract induces apoptosis in gastric cancer by inhibiting NF-kappaB and mTOR-mediated signaling. | ||||||||||
| Author: | Hwang, Jeong Won|Baek, Young-Mi|Yang, Kyeong Eun|Yoo, Hwa-Seung|Cho, Chong-Kwan|Lee, Yeon-Weol|Park, Junsoo|Eom, Chi-Yong|Lee, Zee-Won|Choi, Jong-Soon|Jang, Ik-Soon | ||||||||||
| PMID: | 22505595 | ||||||||||
| 59. | |||||||||||
| Journal: | Oncogene. 2013 Jul 11;32(28):3319-28. | ||||||||||
| Title: | ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer. | ||||||||||
| Author: | Du, W|Wang, S|Zhou, Q|Li, X|Chu, J|Chang, Z|Tao, Q|Ng, E K O|Fang, J|Sung, J J Y|Yu, J | ||||||||||
| PMID: | 22907434 | ||||||||||
| 60. | |||||||||||
| Journal: | Crit Rev Oncol Hematol. 2013 Mar;85(3):350-62. | ||||||||||
| Title: | Advanced HER2-positive gastric cancer: current and future targeted therapies. | ||||||||||
| Author: | Pazo Cid, Roberto A|Anton, Antonio | ||||||||||
| PMID: | 23021388 | ||||||||||
| 61. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2013 Feb;13(2):121-5. | ||||||||||
| Title: | Therapeutic implications of mTOR inhibitors in the treatment of gastric cancer. | ||||||||||
| Author: | Bu, Zhaode|Ji, Jiafu | ||||||||||
| PMID: | 23215721 | ||||||||||
| 62. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Feb;12(2):151-61. | ||||||||||
| Title: | VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. | ||||||||||
| Author: | Hart, Stefan|Novotny-Diermayr, Veronica|Goh, Kee Chuan|Williams, Meredith|Tan, Yong Cheng|Ong, Lai Chun|Cheong, Albert|Ng, Bee Kheng|Amalini, Chithra|Madan, Babita|Nagaraj, Harish|Jayaraman, Ramesh|Pasha, Khalid M|Ethirajulu, Kantharaj|Chng, Wee Joo|Musta | ||||||||||
| PMID: | 23270925 | ||||||||||
| 63. | |||||||||||
| Journal: | Cancer Lett. 2013 May 1;331(2):220-9. | ||||||||||
| Title: | Phosphorylation of 4E-BP1 predicts sensitivity to everolimus in gastric cancer cells. | ||||||||||
| Author: | Nishi, Tetsuo|Iwasaki, Kenta|Ohashi, Norifumi|Tanaka, Chie|Kobayashi, Daisuke|Nakayama, Goro|Koike, Masahiko|Fujiwara, Michitaka|Kobayashi, Takaaki|Kodera, Yasuhiro | ||||||||||
| PMID: | 23340172 | ||||||||||
| 64. | |||||||||||
| Journal: | Int J Oncol. 2013 Apr;42(4):1417-26. | ||||||||||
| Title: | Protective role of autophagy in matrineinduced gastric cancer cell death. | ||||||||||
| Author: | Li, Yumin|Zhang, Junqiang|Ma, Haizhen|Chen, Xiaohui|Liu, Tao|Jiao, Zuoyi|He, Wenting|Wang, Furong|Liu, Xiaokang|Zeng, Xiangting | ||||||||||
| PMID: | 23404079 | ||||||||||
| 65. | |||||||||||
| Journal: | Mol Carcinog. 2013 Nov;52 Suppl 1:E70-9. | ||||||||||
| Title: | Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population. | ||||||||||
| Author: | He, Jing|Wang, Meng-Yun|Qiu, Li-Xin|Zhu, Mei-Ling|Shi, Ting-Yan|Zhou, Xiao-Yan|Sun, Meng-Hong|Yang, Ya-Jun|Wang, Jiu-Cun|Jin, Li|Wang, Ya-Nong|Li, Jin|Yu, Hong-Ping|Wei, Qing-Yi | ||||||||||
| PMID: | 23423739 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer Cell Int. 2013 Feb 21;13(1):18. | ||||||||||
| Title: | Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer. | ||||||||||
| Author: | Xie, Biao|Zhou, Jianping|Shu, Guoshun|Liu, Dong-Cai|Zhou, Jiapeng|Chen, Jinhui|Yuan, Lianwen | ||||||||||
| PMID: | 23432957 | ||||||||||
| 67. | |||||||||||
| Journal: | PLoS One. 2013;8(3):e60080. | ||||||||||
| Title: | A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population. | ||||||||||
| Author: | Xu, Ming|Tao, Guoquan|Kang, Meiyun|Gao, Yan|Zhu, Haixia|Gong, Weida|Wang, Meilin|Wu, Dongmei|Zhang, Zhengdong|Zhao, Qinghong | ||||||||||
| PMID: | 23555892 | ||||||||||
| 68. | |||||||||||
| Journal: | Korean J Gastroenterol. 2013 Mar 25;61(3):117-27. | ||||||||||
| Title: | [Perspectives of the stomach cancer treatment: the introduction of molecular targeted therapy and the hope for cure]. | ||||||||||
| Author: | Cheung, Dae Young|Kim, Jae Kwang | ||||||||||
| PMID: | 23575230 | ||||||||||
| 69. | |||||||||||
| Journal: | Gastroenterology. 2013 Sep;145(3):554-65. | ||||||||||
| Title: | Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil. | ||||||||||
| Author: | Lei, Zhengdeng|Tan, Iain Beehuat|Das, Kakoli|Deng, Niantao|Zouridis, Hermioni|Pattison, Sharon|Chua, Clarinda|Feng, Zhu|Guan, Yeoh Khay|Ooi, Chia Huey|Ivanova, Tatiana|Zhang, Shenli|Lee, Minghui|Wu, Jeanie|Ngo, Anna|Manesh, Sravanthy|Tan, Elisabeth|Teh, B | ||||||||||
| PMID: | 23684942 | ||||||||||
| 70. | |||||||||||
| Journal: | Oncology. 2013;85(2):78-85. | ||||||||||
| Title: | Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer. | ||||||||||
| Author: | Kim, Jong Gwang|Lee, Soo Jung|Chae, Yee Soo|Kang, Byung Woog|Lee, You Jin|Oh, Sung Yong|Kim, Min Chan|Kim, Ki Han|Kim, Su-Jin | ||||||||||
| PMID: | 23860205 | ||||||||||
| 71. | |||||||||||
| Journal: | Int J Oncol. 2013 Nov;43(5):1627-35. | ||||||||||
| Title: | The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer. | ||||||||||
| Author: | Zhang, Chang-Etaua|Awasthi, Niranjan|Schwarz, Margaret A|Schwarz, Roderich E | ||||||||||
| PMID: | 24042258 | ||||||||||
| 72. | |||||||||||
| Journal: | Nat Rev Clin Oncol. 2013 Nov;10(11):643-55. | ||||||||||
| Title: | Gastric cancer-molecular and clinical dimensions. | ||||||||||
| Author: | Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A | ||||||||||
| PMID: | 24061039 | ||||||||||
| 73. | |||||||||||
| Journal: | Mol Cancer. 2013 Sep 25;12(1):110. | ||||||||||
| Title: | Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells. | ||||||||||
| Author: | Li, He|Wang, Juan|Xu, Huiyu|Xing, Rui|Pan, Yuanming|Li, Wenmei|Cui, Jiantao|Zhang, Hongbing|Lu, Youyong | ||||||||||
| PMID: | 24063558 | ||||||||||
| 74. | |||||||||||
| Journal: | Genet Mol Res. 2013 Aug 20;12(3):3038-47. | ||||||||||
| Title: | MicroRNA-199a-3p is downregulated in gastric carcinomas and modulates cell proliferation. | ||||||||||
| Author: | Peng, W|Chen, Z-Y|Wang, L|Wang, Z|Li, J | ||||||||||
| PMID: | 24065659 | ||||||||||
| 75. | |||||||||||
| Journal: | Cancers (Basel). 2013 Jan 10;5(1):15-26. | ||||||||||
| Title: | The Critical Impact of HIF-1a on Gastric Cancer Biology. | ||||||||||
| Author: | Kitajima, Yoshihiko|Miyazaki, Kohji | ||||||||||
| PMID: | 24216696 | ||||||||||
| 76. | |||||||||||
| Journal: | Oncol Lett. 2013 Dec;6(6):1723-1728. | ||||||||||
| Title: | Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells. | ||||||||||
| Author: | Wu, Min|Chen, Yongchang|Jiang, Lu|Li, Yueying|Lan, Ting|Wang, Ying|Qian, Hai | ||||||||||
| PMID: | 24273605 | ||||||||||
| 77. | |||||||||||
| Journal: | Infect Agent Cancer. 2013 Dec 13;8(1):49. | ||||||||||
| Title: | Akt inhibitors: mechanism of action and implications for anticancer therapeutics. | ||||||||||
| Author: | Bhutani, Jaikrit|Sheikh, Asfandyar|Niazi, Asfandyar Khan | ||||||||||
| PMID: | 24330834 | ||||||||||
| 78. | |||||||||||
| Journal: | Am J Transl Res. 2013 Dec 1;6(1):28-42. eCollection 2013. | ||||||||||
| Title: | Transcriptomic changes induced by mycophenolic acid in gastric cancer cells. | ||||||||||
| Author: | Dun, Boying|Sharma, Ashok|Xu, Heng|Liu, Haitao|Bai, Shan|Zeng, Lingwen|She, Jin-Xiong | ||||||||||
| PMID: | 24349619 | ||||||||||
| 79. | |||||||||||
| Journal: | Curr Pharm Des. 2013;19(42):7473-8. | ||||||||||
| Title: | Inhibitory effects of water caltrop pericarps on the growth of human gastric cancer cells in vitro. | ||||||||||
| Author: | Lin, Qiusheng|Shen, Junhui|Ning, Ying|Shen, Shengrong|Das, Undurti N | ||||||||||
| PMID: | 24380421 | ||||||||||
| 80. | |||||||||||
| Journal: | Neoplasia. 2013 Dec;15(12):1391-9. | ||||||||||
| Title: | Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in gastric cancer. | ||||||||||
| Author: | Onoyama, Mieko|Kitadai, Yasuhiko|Tanaka, Yuichiro|Yuge, Ryo|Shinagawa, Kei|Tanaka, Shinji|Yasui, Wataru|Chayama, Kazuaki | ||||||||||
| PMID: | 24403861 | ||||||||||
| 81. | |||||||||||
| Journal: | Hepatogastroenterology. 2013 Oct;60(127):1809-13. | ||||||||||
| Title: | The role of miR-18a in gastric cancer angiogenesis. | ||||||||||
| Author: | Zheng, Yongbin|Li, Shengbo|Ding, Yu|Wang, Qiushuang|Luo, Haiping|Shi, Qiang|Hao, Zhinan|Xiao, Gaochun|Tong, Shilun | ||||||||||
| PMID: | 24624454 | ||||||||||
| 82. | |||||||||||
| Journal: | Cell Biol Int. 2014 Jan;38(1):50-63. | ||||||||||
| Title: | Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation. | ||||||||||
| Author: | Sun, Dan-feng|Zhang, Yan-jie|Tian, Xiao-qing|Chen, Ying-xuan|Fang, Jing-yuan | ||||||||||
| PMID: | 24030871 | ||||||||||
| 83. | |||||||||||
| Journal: | PLoS One. 2014 Jan 9;9(1):e85116. | ||||||||||
| Title: | |||||||||||