Primary Site >> Stomach Cancer

Gene >> MTOR

Journal: Bioorg Med Chem. 2006 Aug 1;14(15):5351-6.
Title: The synthesis and anti-proliferative effects of beta-elemene derivatives with mTOR inhibition activity.
Author: Xu, Liying|Tao, Shujuan|Wang, Xianming|Yu, Zhiying|Wang, Minwei|Chen, Duo|Jing, Yongkui|Dong, Jinhua
PMID: 16617020
Journal: Int J Cancer. 2007 Apr 15;120(8):1803-10.
Title: Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.
Author: Lang, Sven A|Gaumann, Andreas|Koehl, Gudrun E|Seidel, Ulrike|Bataille, Frauke|Klein, Dagmar|Ellis, Lee M|Bolder, Ulrich|Hofstaedter, Ferdinand|Schlitt, Hans-Jurgen|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17230506
Journal: Cancer Biol Ther. 2007 May;6(5):686-90. Epub 2007 Feb 3.
Title: Defibrotide: an endothelium protecting and stabilizing drug, has an anti-angiogenic potential in vitro and in vivo.
Author: Koehl, Gudrun E|Geissler, Edward K|Iacobelli, Massimo|Frei, Caroline|Burger, Verena|Haffner, Silvia|Holler, Ernst|Andreesen, Reinhard|Schlitt, Hans J|Eissner, Gunther
PMID: 17495522
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Aug;24(4):387-91.
Title: [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines].
Author: Sun, Dan-feng|Fang, Jing-yuan|Zhang, Yan-jie|Tian, Xiao-qing|Zhu, Hong-yin|Li, En-ling|Gu, Wei-qi|Shen, Guan-feng
PMID: 17680526
Journal: Planta Med. 2007 Sep;73(11):1176-81. Epub 2007 Sep 7.
Title: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells.
Author: Jiang, Tiejun|Zhu, Yongliang|Luo, Cong|Lu, Xiaoyong|Zhang, Wo|Qiu, Fuming|Huang, Jian
PMID: 17823871
Journal: Carcinogenesis. 2008 Apr;29(4):704-12.
Title: Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.
Author: Kim, Kwang-Kyu|Lee, Jung Joon|Yang, Young|You, Kwan-Hee|Lee, Jeong-Hyung
PMID: 18258606
Journal: Eur J Cancer. 2008 May;44(7):1022-9.
Title: Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells.
Author: Hashimoto, Isaya|Koizumi, Keiichi|Tatematsu, Mikiko|Minami, Takayuki|Cho, Seiji|Takeno, Nobuhiro|Nakashima, Akitoshi|Sakurai, Hiroaki|Saito, Shigeru|Tsukada, Kazuhiro|Saiki, Ikuo
PMID: 18375114
Journal: J Biol Chem. 2008 Jun 6;283(23):15807-15.
Title: Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.
Author: Lin, Ming-Tsan|Kuo, I-Hsin|Chang, Cheng-Chi|Chu, Chia-Yu|Chen, Hsing-Yu|Lin, Been-Ren|Sureshbabu, Munisamy|Shih, Hou-Jung|Kuo, Min-Liang
PMID: 18381294
Journal: Sci China C Life Sci. 2008 Jul;51(7):640-7.
Title: Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines.
Author: Sun, Danfeng|Toan, Xiaoqing|Zhang, Yanjie|Chen, Yingxuan|Lu, Rong|Wang, Xia|Fang, Jingyuan
PMID: 18622747
Journal: Anticancer Res. 2008 Nov-Dec;28(6A):3801-8.
Title: mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
Author: Cejka, Daniel|Preusser, Matthias|Fuereder, Thorsten|Sieghart, Wolfgang|Werzowa, Johannes|Strommer, Sabine|Wacheck, Volker
PMID: 19189667
Journal: Endocr Relat Cancer. 2009 Jun;16(2):599-611.
Title: Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
Author: Alvarez, Carlos J P|Lodeiro, Maria|Theodoropoulou, Marily|Camina, Jesus P|Casanueva, Felipe F|Pazos, Yolanda
PMID: 19153210
Journal: Clin Cancer Res. 2009 Mar 1;15(5):1821-9.
Title: Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer.
Author: Yu, Guanzhen|Wang, Jiejun|Chen, Ying|Wang, Xi|Pan, Jun|Li, Gang|Jia, Zhiliang|Li, Qiang|Yao, James C|Xie, Keping
PMID: 19223493
Journal: Br J Cancer. 2009 Mar 10;100(5):782-8.
Title: Relation between outcomes and localisation of p-mTOR expression in gastric cancer.
Author: Murayama, T|Inokuchi, M|Takagi, Y|Yamada, H|Kojima, K|Kumagai, J|Kawano, T|Sugihara, K
PMID: 19223902
Journal: Int J Oncol. 2009 May;34(5):1231-40.
Title: Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo.
Author: Mishra, Roshan|Miyamoto, Masaki|Yoshioka, Tatsuya|Ishikawa, Keidai|Matsumura, Yoshiyuki|Shoji, Yasuhito|Ichinokawa, Kazuomi|Itoh, Tommo|Shichinohe, Toshiaki|Hirano, Satoshi|Kondo, Satoshi
PMID: 19360336
Journal: J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66.
Title: Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
Author: Arkenau, Hendrik-Tobias
PMID: 19363621
Journal: Transplant Proc. 2009 Apr;41(3):959-61.
Title: Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report.
Author: Lasmar, E P|Coelho, L G V|Lasmar, M F|Lasmar, L F|Lima, P V|Nogueira, A F
PMID: 19376398
Journal: Br J Cancer. 2009 Jun 2;100(11):1739-45.
Title: FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo.
Author: Cejka, D|Kuntner, C|Preusser, M|Fritzer-Szekeres, M|Fueger, B J|Strommer, S|Werzowa, J|Fuereder, T|Wanek, T|Zsebedics, M|Mueller, M|Langer, O|Wacheck, V
PMID: 19436299
Journal: Expert Opin Investig Drugs. 2009 Jul;18(7):945-55.
Title: Novel investigational drugs for gastric cancer.
Author: Vecchione, Loredana|Orditura, Michele|Ciardiello, Fortunato|De Vita, Ferdinando
PMID: 19466878
Journal: Cancer Res. 2009 Sep 15;69(18):7160-4.
Title: mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.
Author: Matsumoto, Kazuko|Arao, Tokuzo|Tanaka, Kaoru|Kaneda, Hiroyasu|Kudo, Kanae|Fujita, Yoshihiko|Tamura, Daisuke|Aomatsu, Keiichi|Tamura, Tomohide|Yamada, Yasuhide|Saijo, Nagahiro|Nishio, Kazuto
PMID: 19738050
Journal: Cancer Sci. 2009 Dec;100(12):2402-10.
Title: Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer.
Author: Matsuzaki, Taro|Yashiro, Masakazu|Kaizaki, Ryoji|Yasuda, Koichi|Doi, Yosuke|Sawada, Tetsuji|Ohira, Masaichi|Hirakawa, Kosei
PMID: 19764996
Journal: J Hematol Oncol. 2009 Oct 27;2:45.
Title: Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy.
Author: Yuan, Ruirong|Kay, Andrea|Berg, William J|Lebwohl, David
PMID: 19860903
Journal: J Exp Clin Cancer Res. 2009 Dec 13;28:152.
Title: The role of mTOR and phospho-p70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarray.
Author: Xiao, Li|Wang, Yi C|Li, Wu S|Du, Yan
PMID: 20003385
Journal: Int J Cancer. 2010 Jun 15;126(12):2904-13.
Title: Prognostic role of p-mTOR expression in cancer tissues and metastatic lymph nodes in pT2b gastric cancer.
Author: An, Ji Yeong|Kim, Kyoung Mee|Choi, Min Gew|Noh, Jae Hyung|Sohn, Tae Sung|Bae, Jae Moon|Kim, Sung
PMID: 19739122
Journal: Int J Cancer. 2010 Jun 1;126(11):2716-25.
Title: Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells.
Author: Shigematsu, Hideo|Yoshida, Kazuhiro|Sanada, Yuichi|Osada, Shinnji|Takahashi, Takao|Wada, Yoshiyuki|Konishi, Kazuo|Okada, Morihito|Fukushima, Masakazu
PMID: 19856312
Journal: Cancer Treat Rev. 2010 May;36(3):235-48.
Title: Esophagogastric cancer: targeted agents.
Author: Ku, Geoffrey Y|Ilson, David H
PMID: 20122806
Journal: Cancer Biol Ther. 2010 Jun 1;9(11):919-27. Epub 2010 Jun 18.
Title: Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo.
Author: Jaeger-Lansky, Agnes|Cejka, Daniel|Ying, Liu|Preusser, Matthias|Hoeflmayer, Doris|Fuereder, Thorsten|Koehrer, Stefan|Wacheck, Volker
PMID: 20404549
Journal: Cancer Lett. 2010 Oct 28;296(2):249-56.
Title: mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo.
Author: Fuereder, Thorsten|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Preusser, Matthias|Strommer, Sabine|Cejka, Daniel|Koehrer, Stefan|Crevenna, Richard|Wacheck, Volker
PMID: 20471160
Journal: Phytother Res. 2010 Dec;24(12):1857-61.
Title: Activation of AMP-activated protein kinase on human gastric cancer cells by apoptosis induced by corosolic acid isolated from Weigela subsessilis.
Author: Lee, Myung Sun|Lee, Chang Min|Cha, Eun Young|Thuong, Phuong Thien|Bae, KiHwan|Song, In Sang|Noh, Seung Moo|Sul, Ji Young
PMID: 20564492
Journal: Cancer Lett. 2010 Dec 18;299(1):22-8.
Title: RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase.
Author: Lee, Kyung-Hun|Hur, Hyung-Seok|Im, Seock-Ah|Lee, Juhee|Kim, Hwang-Phill|Yoon, Young-Kwang|Han, Sae-Won|Song, Sang-Hyun|Oh, Do-Youn|Kim, Tae-You|Bang, Yung-Jue
PMID: 20727673
Journal: BMC Cancer. 2010 Oct 7;10:536.
Title: Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer.
Author: Xu, Da-zhi|Geng, Qi-rong|Tian, Ying|Cai, Mu-yan|Fang, Xin-juan|Zhan, You-qing|Zhou, Zhi-wei|Li, Wei|Chen, Ying-bo|Sun, Xiao-wei|Guan, Yuan-xiang|Li, Yuan-fang|Lin, Tong-yu
PMID: 20929525
Journal: Invest New Drugs. 2011 Dec;29(6):1198-205.
Title: Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination.
Author: Taguchi, Fumiko|Kodera, Yasuo|Katanasaka, Yasufumi|Yanagihara, Kazuyoshi|Tamura, Tomohide|Koizumi, Fumiaki
PMID: 20532589
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: Mol Nutr Food Res. 2011 May;55(5):749-60.
Title: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.
Author: Xing, Xin|Wang, Juan|Xing, Ling Xiao|Li, Yue Hong|Yan, Xia|Zhang, Xiang Hong
PMID: 21287681
Journal: PLoS One. 2011 Feb 18;6(2):e16694.
Title: A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.
Author: Kim, Hark Kyun|Choi, Il Ju|Kim, Chan Gyoo|Kim, Hee Sung|Oshima, Akira|Michalowski, Aleksandra|Green, Jeffrey E
PMID: 21364753
Journal: BMC Cancer. 2011 May 20;11:183.
Title: beta-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis.
Author: Liu, Jing|Zhang, Ye|Qu, Jinglei|Xu, Ling|Hou, Kezuo|Zhang, Jingdong|Qu, Xiujuan|Liu, Yunpeng
PMID: 21595977
Journal: Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1.
Title: Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling.
Author: Wang, Kui|Liu, Rui|Li, Jingyi|Mao, Jiali|Lei, Yunlong|Wu, Jinhua|Zeng, Jun|Zhang, Tao|Wu, Hong|Chen, Lijuan|Huang, Canhua|Wei, Yuquan
PMID: 21610320
Journal: Cancer Treat Rev. 2011 Dec;37(8):599-610.
Title: Molecularly targeted therapies in unresectable-metastatic gastric cancer: a systematic review.
Author: Zagouri, Flora|Papadimitriou, Christos A|Dimopoulos, Meletios-Athanassios|Pectasides, Dimitrios
PMID: 21676549
Journal: Clin Cancer Res. 2011 Aug 15;17(16):5322-32.
Title: Gastric cancer growth control by BEZ235 in vivo does not correlate with PI3K/mTOR target inhibition but with [18F]FLT uptake.
Author: Fuereder, Thorsten|Wanek, Thomas|Pflegerl, Pamina|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Strommer, Sabine|Kuntner, Claudia|Wrba, Friedrich|Werzowa, Johannes|Hejna, Michael|Muller, Markus|Langer, Oliver|Wacheck, Volker
PMID: 21712451
Journal: Chin J Cancer. 2011 Jul;30(7):490-6.
Title: Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells.
Author: Xu, Ling|Qu, Xiu-Juan|Liu, Yun-Peng|Xu, Ying-Ying|Liu, Jing|Hou, Ke-Zuo|Zhang, Ye
PMID: 21718595
Journal: Hepatogastroenterology. 2011 May-Jun;58(107-108):1075-80.
Title: Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin.
Author: Yao, Chun|Liu, Jinxiu|Shao, Liwei
PMID: 21830446
Journal: Anticancer Res. 2011 Oct;31(10):3353-60.
Title: ERas enhances resistance to CPT-11 in gastric cancer.
Author: Kubota, Eiji|Kataoka, Hiromi|Tanaka, Mamoru|Okamoto, Yasuyuki|Ebi, Masahide|Hirata, Yoshikazu|Murakami, Kenji|Mizoshita, Tsutomu|Shimura, Takaya|Mori, Yoshinori|Tanida, Satoshi|Kamiya, Takeshi|Aoyama, Mineyoshi|Asai, Kiyofumi|Joh, Takashi
PMID: 21965746
Journal: Exp Ther Med. 2011 Mar;2(2):251-256.
Title: Prognostic value of co-expression of STAT3, mTOR and EGFR in gastric cancer.
Author: Inokuchi, Mikito|Murayama, Tadao|Hayashi, Mikiko|Takagi, Yoko|Kato, Keiji|Enjoji, Megumu|Kojima, Kazuyuki|Kumagai, Jiro|Sugihara, Kenichi
PMID: 22977493
Journal: Int J Cancer. 2012 Feb 1;130(3):491-6.
Title: mTOR as a therapeutic target in patients with gastric cancer.
Author: Al-Batran, Salah-Eddin|Ducreux, Michel|Ohtsu, Atsushi
PMID: 21898386
Journal: Surg Today. 2012 Apr;42(4):313-27.
Title: Molecular targeted agents for gastric and gastroesophageal junction cancer.
Author: Oshima, Takashi|Masuda, Munetaka
PMID: 22127535
Journal: Mol Cancer Ther. 2012 Feb;11(2):439-51.
Title: Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.
Author: Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22135232
Journal: Int J Oncol. 2012 Apr;40(4):1259-66.
Title: NVP-BKM120, a novel PI3K inhibitor, shows synergism with a STAT3 inhibitor in human gastric cancer cells harboring KRAS mutations.
Author: Park, Eunju|Park, Jinah|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22159814
Journal: Front Biosci (Schol Ed). 2012 Jan 1;4:269-76.
Title: Therapeutics target of CXCR4 and its downstream in peritoneal carcinomatosis of gastric cancer.
Author: Koizumi, Keiichi|Kato, Shinichiro|Sakurai, Hiroaki|Hashimoto, Isaya|Yasumoto, Kazuo|Saiki, Ikuo
PMID: 22202059
Journal: Toxicol Lett. 2012 Apr 5;210(1):78-86.
Title: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells.
Author: Hu, Chen|Zou, Mei-Juan|Zhao, Li|Lu, Na|Sun, Ya-Jing|Gou, Shao-Hua|Xi, Tao|Guo, Qing-Long
PMID: 22322152
Journal: Cancer Biol Ther. 2012 Jan 1;13(1):34-42.
Title: Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells.
Author: Bhattacharya, Bhaskar|Akram, Mohamed|Balasubramanian, Indirikumar|Tam, Kimberley K Y|Koh, King X|Yee, Mei Q|Soong, Richie
PMID: 22336586
Journal: J Biol Chem. 2012 Apr 6;287(15):12132-41.
Title: Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
Author: Chen, Guang|Chen, Si-Meng|Wang, Xiang|Ding, Xiao-Fei|Ding, Jian|Meng, Ling-Hua
PMID: 22337890
Journal: Cell Cycle. 2012 Apr 1;11(7):1414-31.
Title: The roles of REIC gene and its encoding product in gastric carcinoma.
Author: Xu, Xiao-yan|Xia, Pu|Yu, Miao|Nie, Xiao-cui|Yang, Xue|Xing, Ya-nan|Liu, Yun-peng|Takano, Yasuo|Zheng, Hua-chuan
PMID: 22421143
Journal: Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15.
Title: Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.
Author: Mueller, Annett|Bachmann, Erika|Linnig, Monika|Khillimberger, Katrin|Schimanski, Carl Christoph|Galle, Peter R|Moehler, Markus
PMID: 22543857
Journal: Int J Oncol. 2012 Aug;41(2):551-8.
Title: Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
Author: Tomioka, Hideo|Mukohara, Toru|Kataoka, Yu|Ekyalongo, Roudy Chiminch|Funakoshi, Yohei|Imai, Yasuo|Kiyota, Naomi|Fujiwara, Yutaka|Minami, Hironobu
PMID: 22614071
Journal: J Hematol Oncol. 2012 Jun 18;5:31.
Title: Novel targeted agents for gastric cancer.
Author: Liu, Lian|Wu, Ning|Li, Jin
PMID: 22709792
Journal: PLoS One. 2012;7(7):e40037.
Title: Identification of hsa-miR-335 as a prognostic signature in gastric cancer.
Author: Yan, Zhi|Xiong, Yimin|Xu, Weitian|Gao, Juan|Cheng, Yi|Wang, Zhigang|Chen, Fang|Zheng, Guorong
PMID: 22802949
Journal: Biologics. 2012;6:137-46.
Title: Metastatic gastric cancer - focus on targeted therapies.
Author: Meza-Junco, Judith|Sawyer, Michael B
PMID: 22807624
Journal: Oncol Lett. 2012 Dec;4(6):1213-1218.
Title: Immunohistochemical expression of mTOR negatively correlates with PTEN expression in gastric carcinoma.
Author: Li, Min|Sun, Huawen|Song, Lujun|Gao, Xiaodong|Chang, Wenju|Qin, Xinyu
PMID: 23205120
Journal: Integr Cancer Ther. 2013 Mar;12(2):165-73.
Title: Lactobacillus casei extract induces apoptosis in gastric cancer by inhibiting NF-kappaB and mTOR-mediated signaling.
Author: Hwang, Jeong Won|Baek, Young-Mi|Yang, Kyeong Eun|Yoo, Hwa-Seung|Cho, Chong-Kwan|Lee, Yeon-Weol|Park, Junsoo|Eom, Chi-Yong|Lee, Zee-Won|Choi, Jong-Soon|Jang, Ik-Soon
PMID: 22505595
Journal: Oncogene. 2013 Jul 11;32(28):3319-28.
Title: ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.
Author: Du, W|Wang, S|Zhou, Q|Li, X|Chu, J|Chang, Z|Tao, Q|Ng, E K O|Fang, J|Sung, J J Y|Yu, J
PMID: 22907434
Journal: Crit Rev Oncol Hematol. 2013 Mar;85(3):350-62.
Title: Advanced HER2-positive gastric cancer: current and future targeted therapies.
Author: Pazo Cid, Roberto A|Anton, Antonio
PMID: 23021388
Journal: Curr Cancer Drug Targets. 2013 Feb;13(2):121-5.
Title: Therapeutic implications of mTOR inhibitors in the treatment of gastric cancer.
Author: Bu, Zhaode|Ji, Jiafu
PMID: 23215721
Journal: Mol Cancer Ther. 2013 Feb;12(2):151-61.
Title: VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Author: Hart, Stefan|Novotny-Diermayr, Veronica|Goh, Kee Chuan|Williams, Meredith|Tan, Yong Cheng|Ong, Lai Chun|Cheong, Albert|Ng, Bee Kheng|Amalini, Chithra|Madan, Babita|Nagaraj, Harish|Jayaraman, Ramesh|Pasha, Khalid M|Ethirajulu, Kantharaj|Chng, Wee Joo|Musta
PMID: 23270925
Journal: Cancer Lett. 2013 May 1;331(2):220-9.
Title: Phosphorylation of 4E-BP1 predicts sensitivity to everolimus in gastric cancer cells.
Author: Nishi, Tetsuo|Iwasaki, Kenta|Ohashi, Norifumi|Tanaka, Chie|Kobayashi, Daisuke|Nakayama, Goro|Koike, Masahiko|Fujiwara, Michitaka|Kobayashi, Takaaki|Kodera, Yasuhiro
PMID: 23340172
Journal: Int J Oncol. 2013 Apr;42(4):1417-26.
Title: Protective role of autophagy in matrineinduced gastric cancer cell death.
Author: Li, Yumin|Zhang, Junqiang|Ma, Haizhen|Chen, Xiaohui|Liu, Tao|Jiao, Zuoyi|He, Wenting|Wang, Furong|Liu, Xiaokang|Zeng, Xiangting
PMID: 23404079
Journal: Mol Carcinog. 2013 Nov;52 Suppl 1:E70-9.
Title: Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.
Author: He, Jing|Wang, Meng-Yun|Qiu, Li-Xin|Zhu, Mei-Ling|Shi, Ting-Yan|Zhou, Xiao-Yan|Sun, Meng-Hong|Yang, Ya-Jun|Wang, Jiu-Cun|Jin, Li|Wang, Ya-Nong|Li, Jin|Yu, Hong-Ping|Wei, Qing-Yi
PMID: 23423739
Journal: Cancer Cell Int. 2013 Feb 21;13(1):18.
Title: Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer.
Author: Xie, Biao|Zhou, Jianping|Shu, Guoshun|Liu, Dong-Cai|Zhou, Jiapeng|Chen, Jinhui|Yuan, Lianwen
PMID: 23432957
Journal: PLoS One. 2013;8(3):e60080.
Title: A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.
Author: Xu, Ming|Tao, Guoquan|Kang, Meiyun|Gao, Yan|Zhu, Haixia|Gong, Weida|Wang, Meilin|Wu, Dongmei|Zhang, Zhengdong|Zhao, Qinghong
PMID: 23555892
Journal: Korean J Gastroenterol. 2013 Mar 25;61(3):117-27.
Title: [Perspectives of the stomach cancer treatment: the introduction of molecular targeted therapy and the hope for cure].
Author: Cheung, Dae Young|Kim, Jae Kwang
PMID: 23575230
Journal: Gastroenterology. 2013 Sep;145(3):554-65.
Title: Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil.
Author: Lei, Zhengdeng|Tan, Iain Beehuat|Das, Kakoli|Deng, Niantao|Zouridis, Hermioni|Pattison, Sharon|Chua, Clarinda|Feng, Zhu|Guan, Yeoh Khay|Ooi, Chia Huey|Ivanova, Tatiana|Zhang, Shenli|Lee, Minghui|Wu, Jeanie|Ngo, Anna|Manesh, Sravanthy|Tan, Elisabeth|Teh, B
PMID: 23684942
Journal: Oncology. 2013;85(2):78-85.
Title: Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer.
Author: Kim, Jong Gwang|Lee, Soo Jung|Chae, Yee Soo|Kang, Byung Woog|Lee, You Jin|Oh, Sung Yong|Kim, Min Chan|Kim, Ki Han|Kim, Su-Jin
PMID: 23860205
Journal: Int J Oncol. 2013 Nov;43(5):1627-35.
Title: The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer.
Author: Zhang, Chang-Etaua|Awasthi, Niranjan|Schwarz, Margaret A|Schwarz, Roderich E
PMID: 24042258
Journal: Nat Rev Clin Oncol. 2013 Nov;10(11):643-55.
Title: Gastric cancer-molecular and clinical dimensions.
Author: Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A
PMID: 24061039
Journal: Mol Cancer. 2013 Sep 25;12(1):110.
Title: Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells.
Author: Li, He|Wang, Juan|Xu, Huiyu|Xing, Rui|Pan, Yuanming|Li, Wenmei|Cui, Jiantao|Zhang, Hongbing|Lu, Youyong
PMID: 24063558
Journal: Genet Mol Res. 2013 Aug 20;12(3):3038-47.
Title: MicroRNA-199a-3p is downregulated in gastric carcinomas and modulates cell proliferation.
Author: Peng, W|Chen, Z-Y|Wang, L|Wang, Z|Li, J
PMID: 24065659
Journal: Cancers (Basel). 2013 Jan 10;5(1):15-26.
Title: The Critical Impact of HIF-1a on Gastric Cancer Biology.
Author: Kitajima, Yoshihiko|Miyazaki, Kohji
PMID: 24216696
Journal: Oncol Lett. 2013 Dec;6(6):1723-1728.
Title: Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells.
Author: Wu, Min|Chen, Yongchang|Jiang, Lu|Li, Yueying|Lan, Ting|Wang, Ying|Qian, Hai
PMID: 24273605
Journal: Infect Agent Cancer. 2013 Dec 13;8(1):49.
Title: Akt inhibitors: mechanism of action and implications for anticancer therapeutics.
Author: Bhutani, Jaikrit|Sheikh, Asfandyar|Niazi, Asfandyar Khan
PMID: 24330834
Journal: Am J Transl Res. 2013 Dec 1;6(1):28-42. eCollection 2013.
Title: Transcriptomic changes induced by mycophenolic acid in gastric cancer cells.
Author: Dun, Boying|Sharma, Ashok|Xu, Heng|Liu, Haitao|Bai, Shan|Zeng, Lingwen|She, Jin-Xiong
PMID: 24349619
Journal: Curr Pharm Des. 2013;19(42):7473-8.
Title: Inhibitory effects of water caltrop pericarps on the growth of human gastric cancer cells in vitro.
Author: Lin, Qiusheng|Shen, Junhui|Ning, Ying|Shen, Shengrong|Das, Undurti N
PMID: 24380421
Journal: Neoplasia. 2013 Dec;15(12):1391-9.
Title: Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in gastric cancer.
Author: Onoyama, Mieko|Kitadai, Yasuhiko|Tanaka, Yuichiro|Yuge, Ryo|Shinagawa, Kei|Tanaka, Shinji|Yasui, Wataru|Chayama, Kazuaki
PMID: 24403861
Journal: Hepatogastroenterology. 2013 Oct;60(127):1809-13.
Title: The role of miR-18a in gastric cancer angiogenesis.
Author: Zheng, Yongbin|Li, Shengbo|Ding, Yu|Wang, Qiushuang|Luo, Haiping|Shi, Qiang|Hao, Zhinan|Xiao, Gaochun|Tong, Shilun
PMID: 24624454
Journal: Cell Biol Int. 2014 Jan;38(1):50-63.
Title: Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation.
Author: Sun, Dan-feng|Zhang, Yan-jie|Tian, Xiao-qing|Chen, Ying-xuan|Fang, Jing-yuan
PMID: 24030871
Journal: PLoS One. 2014 Jan 9;9(1):e85116.
Title: The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.
Author: Ji, Dongmei|Zhang, Zhe|Cheng, Lei|Chang, Jinjia|Wang, Shanshan|Zheng, Biqiang|Zheng, Rongliang|Sun, Zuojun|Wang, Chenchen|Zhang, Zhiqing|Liu, Rujiao|Zhang, Xiaowei|Liu, Xin|Wang, Xiaofeng|Li, Jin
PMID: 24416349
Journal: Biochem Biophys Res Commun. 2014 Mar 28;446(1):105-12.
Title: Antibiotic drug tigecycline inhibited cell proliferation and induced autophagy in gastric cancer cells.
Author: Tang, Chunling|Yang, Liqun|Jiang, Xiaolan|Xu, Chuan|Wang, Mei|Wang, Qinrui|Zhou, Zhansong|Xiang, Zhonghuai|Cui, Hongjuan
PMID: 24582751
Journal: Br J Pharmacol. 2014 Jul;171(13):3255-67.
Title: Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype.
Author: Bhattacharya, B|Low, S H H|Soh, C|Kamal Mustapa, N|Beloueche-Babari, M|Koh, K X|Loh, J|Soong, R
PMID: 24597478
Journal: J Surg Oncol. 2014 Jun;109(8):812-7.
Title: Prognostic implication of TSC1 and mTOR expression in gastric carcinoma.
Author: Byeon, Sun-Ju|Han, Nayoung|Choi, Jiwoon|Kim, Min A|Kim, Woo Ho
PMID: 24615476
Journal: Expert Rev Gastroenterol Hepatol. 2014 Jul;8(5):555-69.
Title: Recent advances and future trends in the targeted therapy of metastatic gastric cancer.
Author: Al-Batran, Salah-Eddin|Werner, Dominique
PMID: 24665840
Journal: BMB Rep. 2014 Dec;47(12):697-702.
Title: Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy.
Author: Lee, Hyun-Woo|Jang, Kenny Seung Bin|Choi, Hye Ji|Jo, Ara|Cheong, Jae-Ho|Chun, Kyung-Hee
PMID: 24667175
Journal: J Cancer Res Clin Oncol. 2014 Aug;140(8):1399-411.
Title: A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Author: Wang, Xiaoting|Lin, Youdong|Lan, Fenghua|Yu, Yinghao|Ouyang, Xuenong|Wang, Xuzhou|Huang, Qiaojia|Wang, Lie|Tan, Jianming|Zheng, Feng
PMID: 24737346
Journal: J Cancer. 2014 Apr 24;5(5):382-9.
Title: Carnosine Inhibits the Proliferation of Human Gastric Carcinoma Cells by Retarding Akt/mTOR/p70S6K Signaling.
Author: Zhang, Zhenwei|Miao, Lei|Wu, Xin|Liu, Guangze|Peng, Yuting|Xin, Xiaoming|Jiao, Binghua|Kong, Xiangping
PMID: 24799956
Journal: Oncotarget. 2014 Apr 30;5(8):2276-92.
Title: Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a.
Author: Zhang, Er-bao|Kong, Rong|Yin, Dan-dan|You, Liang-hui|Sun, Ming|Han, Liang|Xu, Tong-peng|Xia, Rui|Yang, Jin-song|De, Wei|Chen, Jin fei
PMID: 24810364
Journal: Virchows Arch. 2014 Jul;465(1):25-33.
Title: The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance.
Author: Tapia, Oscar|Riquelme, Ismael|Leal, Pamela|Sandoval, Alejandra|Aedo, Susana|Weber, Helga|Letelier, Pablo|Bellolio, Enrique|Villaseca, Miguel|Garcia, Patricia|Roa, Juan Carlos
PMID: 24844205
Journal: Anticancer Agents Med Chem. 2014;14(6):884-91.
Title: miR-1271 regulates cisplatin resistance of human gastric cancer cell lines by targeting IGF1R, IRS1, mTOR, and BCL2.
Author: Yang, Mifang|Shan, Xia|Zhou, Xin|Qiu, Tianzhu|Zhu, Wei|Ding, Yin|Shu, Yongqian|Liu, Ping
PMID: 24875127
Journal: Nucleic Acids Res. 2014 Jul;42(12):8062-72.
Title: MicroRNA-382 induced by HIF-1alpha is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog.
Author: Seok, Jin-Kyung|Lee, Sun Hee|Kim, Min Jung|Lee, You-Mie
PMID: 24914051
Journal: Oncol Rep. 2014 Sep;32(3):973-8.
Title: Anti-apoptotic and apoptotic pathway analysis of arsenic trioxideinduced apoptosis in human gastric cancer SGC-7901 cells.
Author: Yu, Yao|Yang, Yu|Wang, Jing
PMID: 24969414
Journal: Cancer Radiother. 2014 Nov;18(7):681-4.
Title: [Concurrent association of reirradiation therapy with everolimus for lymph node metastasis of gastroesophageal junction cancer: a case report].
Author: Pernin, V|Beuzeboc, P|Peurien, D|Louvet, C|Kirova, Y
PMID: 24981410
Journal: Cancers (Basel). 2014 Jul 7;6(3):1441-63.
Title: The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma.
Author: Matsuoka, Tasuku|Yashiro, Masakazu
PMID: 25003395
Journal: Anticancer Drugs. 2014 Nov;25(10):1129-40.
Title: PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway.
Author: Xing, Xiaofang|Zhang, Lianhai|Wen, Xianzi|Wang, Xiaohong|Cheng, Xiaojing|Du, Hong|Hu, Ying|Li, Lin|Dong, Bin|Li, Ziyu|Ji, Jiafu
PMID: 25035961
Journal: PLoS One. 2014 Oct 6;9(10):e107362.
Title: Mechanisms of GOLPH3 associated with the progression of gastric cancer: a preliminary study.
Author: Peng, Jinzhen|Fang, Ye|Tao, Yong|Li, Keke|Su, Ting|Nong, Yuncui|Xie, Fang|Lai, Mingyu
PMID: 25286393
Journal: Oncotarget. 2014 Dec 15;5(23):11873-85.
Title: Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A.
Author: Chen, Hongxia|Li, Lingmin|Wang, Shaojun|Lei, Yupeng|Ge, Qi|Lv, Nonghua|Zhou, Xiaodong|Chen, Changyan
PMID: 25428912
Journal: Crit Rev Oncog. 2014;19(6):469-81.
Title: Role of Raf kinase inhibitor protein in Helicobacter pylori-mediated signaling in gastric cancer.
Author: Nisimova, Liana|Wen, Sicheng|Cross-Knorr, Sam|Rogers, Arlin B|Moss, Steven F|Chatterjee, Devasis
PMID: 25597356
Journal: Int J Hematol Oncol Stem Cell Res. 2014 Jul 1;8(3):12-9.
Title: Evaluation of antagonistic effects of metformin with Cisplatin in gastric cancer cells.
Author: Lesan, Vahid|Ghaffari, Seyed H|Salaramoli, Jamile|Heidari, Mansour|Rostami, Masoumeh|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir
PMID: 25642303
Journal: Gastric Cancer. 2015 Jan;18(1):65-76.
Title: Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer.
Author: Yoda, Yukie|Takeshima, Hideyuki|Niwa, Tohru|Kim, Jeong Goo|Ando, Takayuki|Kushima, Ryoji|Sugiyama, Toshiro|Katai, Hitoshi|Noshiro, Hirokazu|Ushijima, Toshikazu
PMID: 24510342
Journal: Mol Med Rep. 2015 Jan;11(1):670-6.
Title: An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IkappaBalpha.
Author: Hwang, Jeong-Won|Baek, Young-Mi|Jang, Ik-Soon|Yang, Kyeong Eun|Lee, Dong-Gi|Yoon, So-Jung|Rho, Jaerang|Cho, Chong-Kwan|Lee, Yeon-Weol|Kwon, Ki-Rok|Yoo, Hwa-Seung|Sung, Jung-Suk|Kim, Shin|Park, Jong-Wook|Jang, Byeong-Churl|Choi, Jong-Soon
PMID: 25333578
Journal: Cancer Biol Ther. 2015;16(1):77-87.
Title: AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell.
Author: Han, Gang|Gong, Hangjun|Wang, Yidong|Guo, Shaowen|Liu, Kun
PMID: 25456211
Journal: Cancer Lett. 2015 Mar 1;358(1):17-26.
Title: Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: involvement of the Akt-mTOR signaling pathway.
Author: Zhao, Zhi|Han, Fanghai|Yang, Shibin|Wu, Jianhai|Zhan, Wenhua
PMID: 25524555
Journal: Tumour Biol. 2015 Jun;36(6):4519-23.
Title: Insulin-like growth factor 1 promotes growth of gastric cancer by inhibiting foxo1 nuclear retention.
Author: Li, Shuangling|Lei, Xiaofei|Zhang, Jianna|Yang, Hongli|Liu, Jiyong|Xu, Changqing
PMID: 25596089
Journal: Drug Des Devel Ther. 2015 Jan 14;9:487-508.
Title: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
Author: Yuan, Chun-Xiu|Zhou, Zhi-Wei|Yang, Yin-Xue|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Tianxing|Wang, Ning-Ju|Zhao, Ruan Jin|Zhou, Shu-Feng
PMID: 25609923
Journal: Am J Cancer Res. 2014 Dec 15;5(1):321-32. eCollection 2015.
Title: Overexpression of CDX2 in gastric cancer cells promotes the development of multidrug resistance.
Author: Yan, Lin-Hai|Wei, Wei-Yuan|Cao, Wen-Long|Zhang, Xiao-Shi|Xie, Yu-Bo|Xiao, Qiang
PMID: 25628941
Journal: Tumour Biol. 2015 Jul;36(7):5607-15.
Title: Celecoxib sensitizes gastric cancer to rapamycin via inhibition of the Cbl-b-regulated PI3K/Akt pathway.
Author: Cao, Yubo|Qu, Jinglei|Li, Ce|Yang, Dan|Hou, Kezuo|Zheng, Huachuan|Liu, Yunpeng|Qu, Xiujuan
PMID: 25701378
Journal: APMIS. 2015 May;123(5):365-72.
Title: Targeted therapy in gastric cancer.
Author: Thiel, Alexandra|Ristimaki, Ari
PMID: 25706252
Journal: World J Gastroenterol. 2015 Feb 28;21(8):2323-35.
Title: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation.
Author: Cheng, Ya-Jun|Zhu, Zhen-Xin|Zhou, Jian-Sheng|Hu, Zun-Qi|Zhang, Jian-Peng|Cai, Qing-Ping|Wang, Liang-Hua
PMID: 25741138
Journal: Drug Des Devel Ther. 2015 Mar 2;9:1293-318.
Title: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N
Author: Yuan, Chun-Xiu|Zhou, Zhi-Wei|Yang, Yin-Xue|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Tianxing|Pan, Si-Yuan|Chen, Xiao-Wu|Zhou, Shu-Feng
PMID: 25767376
Journal: PLoS One. 2015 Mar 18;10(3):e0119415.
Title: Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFalpha-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction.
Author: Kawada, Manabu|Inoue, Hiroyuki|Ohba, Shun-ichi|Yoshida, Junjiro|Masuda, Tohru|Yamasaki, Manabu|Usami, Ihomi|Sakamoto, Shuichi|Abe, Hikaru|Watanabe, Takumi|Yamori, Takao|Shibasaki, Masakatsu|Nomoto, Akio
PMID: 25785838
Journal: Nutr Cancer. 2015;67(3):523-31.
Title: Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells.
Author: Yi, Tingting|Zhuang, Luhua|Song, Gang|Zhang, Bing|Li, Guideng|Hu, Tianhui
PMID: 25837881
Journal: Expert Opin Pharmacother. 2015 May;16(7):955-60.
Title: Biologics in combination with chemotherapy for gastric cancer: is this the answer?
Author: Charalampakis, Nikolaos|Elimova, Elena|Shimodaira, Yusuke|Shiozaki, Hironori|Wadhwa, Roopma|Ajani, Jaffer A
PMID: 25850442
Journal: BMC Cancer. 2015 Mar 7;15:103.
Title: Lymphangiogenesis in gastric cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis.
Author: Chen, Hongxia|Guan, Runnian|Lei, Yupeng|Chen, Jianyong|Ge, Qi|Zhang, Xiaoshen|Dou, Ruoxu|Chen, Hongyuan|Liu, Hao|Qi, Xiaolong|Zhou, Xiaodong|Chen, Changyan
PMID: 25884175
Journal: BMC Cancer. 2015 Mar 13;15:119.
Title: Successful control of heavily pretreated metastatic gastric cancer with the mTOR inhibitor everolimus (RAD001) in a patient with PIK3CA mutation and pS6 overexpression.
Author: Park, Ji Hyun|Ryu, Min-Hee|Park, Young Soo|Park, Sook Ryun|Na, Young-Soon|Rhoo, Baek-Yeol|Kang, Yoon-Koo
PMID: 25886409
Journal: Oncotarget. 2015 May 20;6(14):12748-62.
Title: Metformin potentiates rapamycin and cisplatin in gastric cancer in mice.
Author: Yu, Guanzhen|Fang, Wenzheng|Xia, Tian|Chen, Ying|Gao, Yunshu|Jiao, Xiaodong|Huang, Suyun|Wang, Jiejun|Li, Zhaosheng|Xie, Keping
PMID: 25909163
Journal: Biochem Biophys Res Commun. 2015 Jul 3;462(3):227-32.
Title: Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance.
Author: Zhang, Xian-wen|Bu, Ping|Liu, Liang|Zhang, Xi-zhi|Li, Jun
PMID: 25956062
Journal: Sci Rep. 2015 May 18;5:10336.
Title: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways.
Author: Hao, Wenjin|Yuan, Xuan|Yu, Lina|Gao, Caixia|Sun, Xiling|Wang, Dong|Zheng, Qiusheng
PMID: 25981581
Journal: Expert Opin Emerg Drugs. 2015 Sep;20(3):479-93.
Title: Emerging kinase inhibitors of the treatment of gastric cancer.
Author: Vincenzi, Bruno|Imperatori, Marco|Silletta, Marianna|Marrucci, Eleonora|Santini, Daniele|Tonini, Giuseppe
PMID: 26021342
Journal: Oncotarget. 2015 Aug 14;6(23):19685-705.
Title: BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy.
Author: Zheng, Hua-chuan|Li, Jing|Shen, Dao-fu|Yang, Xue-feng|Zhao, Shuang|Wu, Ya-zhou|Takano, Yasuo|Sun, Hong-zhi|Su, Rong-jian|Luo, Jun-sheng|Gou, Wen-feng
PMID: 26050197
Journal: Mol Med Rep. 2015 Sep;12(3):4782-4788.
Title: Corosolic acid enhances 5-fluorouracil-induced apoptosis against SNU-620 human gastric carcinoma cells by inhibition of mammalian target of rapamycin.
Author: Lee, Hyun Su|Park, Jun Beom|Lee, Myung Sun|Cha, Eun Young|Kim, Ji Yeon|Sul, Ji Young
PMID: 26100106
Journal: PLoS One. 2015 Jul 6;10(7):e0130839.
Title: Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas.
Author: Choi, Euno|Byeon, Sun-ju|Kim, Soo Hee|Lee, Hyun Ju|Kwon, Hyeong Ju|Ahn, HyeSeong|Kim, Dong Ha|Chang, Mee Soo
PMID: 26147886
Journal: Biochem Biophys Res Commun. 2015 Aug 21;464(2):534-40.
Title: Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer.
Author: Bian, Yuhai|Wang, Zhengshi|Xu, Jia|Zhao, Wenyi|Cao, Hui|Zhang, Zhigang
PMID: 26159923
Journal: PLoS One. 2015 Jul 13;10(7):e0132829.
Title: Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation.
Author: Hou, Liying|Li, Yuze|Song, Huacui|Zhang, Zhihong|Sun, Yanpei|Zhang, Xuguang|Wu, Kun
PMID: 26168048
Journal: Int J Oncol. 2015 Sep;47(3):1061-9.
Title: Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells.
Author: Raha, Suchismita|Yumnam, Silvia|Hong, Gyeong Eun|Lee, Ho Jeong|Saralamma, Venu Venkatarame Gowda|Park, Hyeon-Soo|Heo, Jeong Doo|Lee, Sang Joon|Kim, Eun Hee|Kim, Jin-A|Kim, Gon Sup
PMID: 26201693
Journal: Oncotarget. 2015 Sep 22;6(28):24750-79.
Title: Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy.
Author: Riquelme, Ismael|Saavedra, Kathleen|Espinoza, Jaime A|Weber, Helga|Garcia, Patricia|Nervi, Bruno|Garrido, Marcelo|Corvalan, Alejandro H|Roa, Juan Carlos|Bizama, Carolina
PMID: 26267324
Journal: Pharmacogenet Genomics. 2015 Nov;25(11):521-30.
Title: Genetic variations in the mTOR gene contribute toward gastric adenocarcinoma susceptibility in an Eastern Chinese population.
Author: Wang, Meng-Yun|Li, Qiao-Xin|He, Jing|Qiu, Li-Xin|Wang, Ya-Nong|Li, Jin|Sun, Meng-Hong|Wang, Xiao-Feng|Yang, Ya-Jun|Wang, Jiu-Cun|Jin, Li|Wei, Qing-Yi
PMID: 26287940
Journal: PLoS One. 2015 Aug 28;10(8):e0136447.
Title: Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
Author: Piao, Ying|Li, Ying|Xu, Qian|Liu, Jing-wei|Xing, Cheng-zhong|Xie, Xiao-dong|Yuan, Yuan
PMID: 26317520
Journal: Int J Nanomedicine. 2015 Aug 25;10 Spec Iss:143-53.
Title: Anticancer activities of self-assembled molecular bowls containing a phenanthrene-based donor and Ru(II) acceptors.
Author: Kim, Inhye|Song, Young Ho|Singh, Nem|Jeong, Yong Joon|Kwon, Jung Eun|Kim, Hyunuk|Cho, Young Mi|Kang, Se Chan|Chi, Ki-Whan
PMID: 26347134
Journal: Evid Based Complement Alternat Med. 2015;2015:402385.
Title: Auraptene, a Major Compound of Supercritical Fluid Extract of Phalsak (Citrus Hassaku Hort ex Tanaka), Induces Apoptosis through the Suppression of mTOR Pathways in Human Gastric Cancer SNU-1 Cells.
Author: Moon, Jeong Yong|Kim, Hyeonji|Cho, Somi Kim
PMID: 26351512
Journal: Onco Targets Ther. 2015 Sep 1;8:2427-33.
Title: The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis.
Author: Ying, Jieer|Xu, Qi|Liu, Bixia|Zhang, Gu|Chen, Lei|Pan, Hongming
PMID: 26366097
Journal: Int J Oncol. 2015 Nov;47(5):1617-26.
Title: The JAK/STAT signaling cascade in gastric carcinoma (Review).
Author: Khanna, Puja|Chua, Pei Jou|Bay, Boon Huat|Baeg, Gyeong Hun
PMID: 26398764
Journal: Cancer Cell Int. 2015 Oct 24;15:101.
Title: Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer.
Author: Sha, Min|Ye, Jun|Luan, Zheng-Yun|Guo, Ting|Wang, Bian|Huang, Jun-Xing
PMID: 26500453
Journal: Oncotarget. 2015 Dec 15;6(40):42813-24.
Title: LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway.
Author: Ji, Jie|Tang, Junwei|Deng, Lei|Xie, Yu|Jiang, Runqiu|Li, Guoqiang|Sun, Beicheng
PMID: 26540343
Journal: BMC Cancer. 2015 Nov 11;15:894.
Title: Dual PI3K/mTOR inhibitor BEZ235 exerts extensive antitumor activity in HER2-positive gastric cancer.
Author: Zhu, Yan|Tian, Tiantian|Zou, Jianling|Wang, Qiwei|Li, Zhongwu|Li, Yanyan|Liu, Xijuan|Dong, Bin|Li, Na|Gao, Jing|Shen, Lin
PMID: 26560145
Journal: World J Gastroenterol. 2015 Nov 21;21(43):12261-73.
Title: Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
Author: Singh, Shikha Satendra|Yap, Wei Ney|Arfuso, Frank|Kar, Shreya|Wang, Chao|Cai, Wanpei|Dharmarajan, Arunasalam M|Sethi, Gautam|Kumar, Alan Prem
PMID: 26604635
Journal: Diagn Pathol. 2015 Dec 12;10:212.
Title: MMP2 and MMP7 at the invasive front of gastric cancer are not associated with mTOR expression.
Author: Bornschein, Jan|Seidel, Tina|Langner, Cosima|Link, Alexander|Wex, Thomas|Selgrad, Michael|Jechorek, Doerthe|Meyer, Frank|Bird-Lieberman, Elizabeth|Vieth, Michael|Malfertheiner, Peter
PMID: 26652716
Journal: Zhongguo Zhong Yao Za Zhi. 2015 Aug;40(16):3262-6.
Title: [Effect of evodiamine in inducing apoptosis of gastric cancer SGC-7901 cells through mTOR signal pathway].
Author: Liu, Xin|Yang, Li|Bi, Ying|Wang, Liang-hong|Huang, Hai
PMID: 26790304
Journal: Cell Oncol (Dordr). 2016 Feb;39(1):23-33.
Title: miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
Author: Riquelme, Ismael|Tapia, Oscar|Leal, Pamela|Sandoval, Alejandra|Varga, Matthew G|Letelier, Pablo|Buchegger, Kurt|Bizama, Carolina|Espinoza, Jaime A|Peek, Richard M|Araya, Juan Carlos|Roa, Juan Carlos
PMID: 26458815
Journal: Tumour Biol. 2016 Apr;37(4):4803-11.
Title: Reciprocal expression of p-AMPKa and p-S6 is strongly associated with the prognosis of gastric cancer.
Author: Zheng, Zhendong|Zheng, Yingjuan|Zhang, Meiyan|Wang, Jiejun|Yu, Guanzhen|Fang, Wenzheng
PMID: 26520441
Journal: Crit Rev Oncol Hematol. 2016 Mar;99:1-12.
Title: Systemic therapy beyond first-line in advanced gastric cancer: An overview of the main randomized clinical trials.
Author: Galdy, Salvatore|Cella, Chiara Alessandra|Spada, Francesca|Murgioni, Sabina|Frezza, Anna Maria|Ravenda, Simona Paola|Zampino, Maria Giulia|Fazio, Nicola
PMID: 26697987
Journal: Oncol Rep. 2016 Mar;35(3):1245-54.
Title: Targeted therapy for gastric cancer: Current status and future directions (Review).
Author: Yuan, Dan-Dan|Zhu, Zhong-Xiu|Zhang, Xia|Liu, Jie
PMID: 26718131
Journal: J Exp Clin Cancer Res. 2016 Jan 4;35:1.
Title: Molecular targeted therapy for the treatment of gastric cancer.
Author: Xu, Wenting|Yang, Zhen|Lu, Nonghua
PMID: 26728266
Journal: J Biol Chem. 2016 Feb 26;291(9):4462-72.
Title: The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway.
Author: Jia, Sheng-Nan|Lin, Cheng|Chen, Dian-Fu|Li, An-Qi|Dai, Li|Zhang, Li|Zhao, Ling-Ling|Yang, Jin-Shu|Yang, Fan|Yang, Wei-Jun
PMID: 26733200
Journal: Biochem Biophys Res Commun. 2016 Feb 5;470(2):350-355.
Title: Mefloquine effectively targets gastric cancer cells through phosphatase-dependent inhibition of PI3K/Akt/mTOR signaling pathway.
Author: Liu, Yanwei|Chen, Sen|Xue, Rui|Zhao, Juan|Di, Maojun
PMID: 26780727
Journal: Oncotarget. 2016 Mar 1;7(9):10255-70.
Title: Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.
Author: Syu, Li-Jyun|Zhao, Xinyi|Zhang, Yaqing|Grachtchouk, Marina|Demitrack, Elise|Ermilov, Alexandre|Wilbert, Dawn M|Zheng, Xinlei|Kaatz, Ashley|Greenson, Joel K|Gumucio, Deborah L|Merchant, Juanita L|di Magliano, Marina Pasca|Samuelson, Linda C|Dlugosz, Andrze
PMID: 26859571
Journal: Oncotarget. 2016 Mar 1;7(9):10547-56.
Title: Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus.
Author: Lim, Sun Min|Park, Hyung Soon|Kim, Sangwoo|Kim, Sora|Ali, Siraj M|Greenbowe, Joel R|Yang, In Seok|Kwon, Nak-Jung|Lee, Jae Lyun|Ryu, Min-Hee|Ahn, Jin-Hee|Lee, Jeeyun|Lee, Min Goo|Kim, Hyo Song|Kim, Hyunki|Kim, Hye Ryun|Moon, Yong Wha|Chung, Hyun Cheol|Kim,
PMID: 26859683
Journal: Invest New Drugs. 2016 Jun;34(3):378-93.
Title: Targeted therapies in gastric cancer treatment: where we are and where we are going.
Author: Tomasello, Gianluca|Ghidini, Michele|Liguigli, Wanda|Ratti, Margherita|Toppo, Laura|Passalacqua, Rodolfo
PMID: 26873643
Journal: Gastroenterol Res Pract. 2016;2016:4105615.
Title: Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application.
Author: Li, Kaichun|Li, Jin
PMID: 26880889
Journal: Oncol Res. 2016;23(3):99-107.
Title: Long Noncoding RNA H19-Derived miR-675 Enhances Proliferation and Invasion via RUNX1 in Gastric Cancer Cells.
Author: Liu, Gao|Xiang, Tian|Wu, Quan-Feng|Wang, Wei-Xing
PMID: 26931432
Journal: World J Surg Oncol. 2016 Mar 10;14:77.
Title: The potential of deferasirox as a novel therapeutic modality in gastric cancer.
Author: Choi, Jung Hye|Kim, Jung Soon|Won, Young Woong|Uhm, Jieun|Park, Byeong Bae|Lee, Young Yiul
PMID: 26965928
Journal: Oncol Lett. 2016 Mar;11(3):1745-1749.
Title: miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway.
Author: Li, N A|Wang, Weiqiang|Xu, Bin|Gong, Hongyun
PMID: 26998071
Journal: J Ethnopharmacol. 2016 Jun 20;186:143-150.
Title: Huaier aqueous extract sensitizes cells to rapamycin and cisplatin through activating mTOR signaling.
Author: Hu, Zhongdong|Yang, Ailin|Fan, Haitao|Wang, Ying|Zhao, Yunfang|Zha, Xiaojun|Zhang, Hongbing|Tu, Pengfei
PMID: 27045863
Journal: Cell Biol Int. 2016 Jul;40(7):770-8.
Title: Oleanolic acid induces autophagic death in human gastric cancer cells in vitro and in vivo.
Author: Nie, Hao|Wang, Yu|Qin, Yong|Gong, Xing-Guo
PMID: 27079177
Journal: Eur J Pharmacol. 2016 Jun 15;781:164-72.
Title: DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation.
Author: Li, Hongyang|Sun, Li|de Carvalho, Evandro Lopes|Li, Xinxin|Lv, Xiaodan|Khan, Ghulam Jilany|Semukunzi, Herve|Yuan, Shengtao|Lin, Sensen
PMID: 27079642
Journal: Oncotarget. 2016 Jun 7;7(23):34190-200.
Title: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.
Author: Wu, Yan|Yao, Xiaoyuan|Zhu, Miaolin|Qian, Hai|Jiang, Lu|Lan, Ting|Wu, Min|Pang, Ji|Chen, Yongchang
PMID: 27147579
Journal: Pathol Oncol Res. 2016 Oct;22(4):797-805.
Title: The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines.
Author: Riquelme, Ismael|Tapia, Oscar|Espinoza, Jaime A|Leal, Pamela|Buchegger, Kurt|Sandoval, Alejandra|Bizama, Carolina|Araya, Juan Carlos|Peek, Richard M|Roa, Juan Carlos
PMID: 27156070
Journal: Cancer Discov. 2016 Aug;6(8):838-851.
Title: High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.
Author: Pearson, Alex|Smyth, Elizabeth|Babina, Irina S|Herrera-Abreu, Maria Teresa|Tarazona, Noelia|Peckitt, Clare|Kilgour, Elaine|Smith, Neil R|Geh, Catherine|Rooney, Claire|Cutts, Ros|Campbell, James|Ning, Jian|Fenwick, Kerry|Swain, Amanda|Brown, Gina|Chua, Sue
PMID: 27179038
Journal: World J Gastroenterol. 2016 May 21;22(19):4638-50.
Title: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management.
Author: Joo, Moon Kyung|Park, Jong-Jae|Chun, Hoon Jai
PMID: 27217696
Journal: Mol Med Rep. 2016 Aug;14(2):1210-8.
Title: Autophagic death induced by thermochemotherapy in gastric cancer cells results from the reactive oxygen species pathway.
Author: Wu, Yinbing|Pan, Mingxin|Cui, Shuzhong|Ba, Mingchen|Chen, Zulong|Ruan, Qiang
PMID: 27277337
Journal: Oncol Rep. 2016 Aug;36(2):1173-9.
Title: Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo.
Author: Su, Chin-Cheng|Chiu, Tsung-Lang
PMID: 27277844
Journal: J Pathol. 2016 Oct;240(2):137-48.
Title: Comprehensive mutation profiling of mucinous gastric carcinoma.
Author: Rokutan, Hirofumi|Hosoda, Fumie|Hama, Natsuko|Nakamura, Hiromi|Totoki, Yasushi|Furukawa, Eisaku|Arakawa, Erika|Ohashi, Shoko|Urushidate, Tomoko|Satoh, Hironori|Shimizu, Hiroko|Igarashi, Keiko|Yachida, Shinichi|Katai, Hitoshi|Taniguchi, Hirokazu|Fukayama,
PMID: 27313181
Journal: Cancer Biomark. 2016 Jun 7;17(1):1-10.
Title: Autophagy regulation and its role in gastric cancer and colorectal cancer.
Author: Zhou, Huangyan|Yuan, Min|Yu, Qiongfang|Zhou, Xiaoyan|Min, Weiping|Gao, Dian
PMID: 27314289
Journal: Int J Oncol. 2016 Sep;49(3):1068-80.
Title: MicroRNA-224 aggrevates tumor growth and progression by targeting mTOR in gastric cancer.
Author: Zhang, Ying|Li, Chang-Feng|Ma, Lian-Jun|Ding, Meng|Zhang, Bin
PMID: 27315344
Journal: Sci Rep. 2016 Jul 8;6:29382.
Title: Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer.
Author: Chen, Jing|Guo, Jiawei|Chen, Zhi|Wang, Jieqiong|Liu, Mingyao|Pang, Xiufeng
PMID: 27387652
Journal: Am J Cancer Res. 2016 Jun 1;6(6):1420-30. eCollection 2016.
Title: URI promotes gastric cancer cell motility, survival, and resistance to adriamycin in vitro.
Author: Hu, Xiaoxia|Zhang, Fei|Luo, Dongwei|Li, Na|Wang, Qian|Xu, Zhonghai|Bian, Huiqin|Liang, Yuting|Lu, Yaojuan|Zheng, Qiping|Gu, Junxia
PMID: 27429854
Journal: Mar Drugs. 2016 Jul 27;14(8). pii: md14080142.
Title: Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells.
Author: Wu, Yu-Jen|Wong, Bing-Sang|Yea, Shu-Hao|Lu, Chi-I|Weng, Shun-Hsiang
PMID: 27472346
Journal: Int J Oncol. 2016 Oct;49(4):1589-99.
Title: Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer.
Author: Zeng, Yang|Fu, Meng|Wu, Gang-Wei|Zhang, An-Zu|Chen, Jin-Ping|Lin, Hong-Yue|Fu, Yong-An|Jia, Jing|Cai, Zong-Da|Wu, Xiao-Jian|Lan, Ping
PMID: 27499479
Journal: Onco Targets Ther. 2016 Aug 9;9:4859-66.
Title: Oncogenic NanogP8 expression regulates cell proliferation and migration through the Akt/mTOR signaling pathway in human gastric cancer - SGC-7901cell line.
Author: Jiang, Zheng|Liu, Yao|Wang, Chuan
PMID: 27563247
Journal: Oncol Rep. 2016 Oct;36(4):2216-24.
Title: RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer.
Author: Wang, Wenwen|Liu, Juan|Qi, Jianni|Zhang, Junyong|Zhu, Qiang|Qin, Chengyong
PMID: 27572296
Journal: Int J Oncol. 2016 Nov;49(5):1881-1889.
Title: Cancer stem cell marker CD90 inhibits ovarian cancer formation via beta3 integrin.
Author: Chen, Wei-Ching|Hsu, Hui-Ping|Li, Chung-Yen|Yang, Ya-Ju|Hung, Yu-Hsuan|Cho, Chien-Yu|Wang, Chih-Yang|Weng, Tzu-Yang|Lai, Ming-Derg
PMID: 27633757
Journal: Redox Biol. 2016 Dec;10:78-89.
Title: Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer.
Author: Chen, Weiqian|Zou, Peng|Zhao, Zhongwei|Chen, Xi|Fan, Xiaoxi|Vinothkumar, Rajamanickam|Cui, Ri|Wu, Fazong|Zhang, Qianqian|Liang, Guang|Ji, Jiansong
PMID: 27697670
Journal: Oncol Res. 2016;24(5):287-293.
Title: Knockdown of Rap1b Enhances Apoptosis and Autophagy in Gastric Cancer Cells via the PI3K/Akt/mTOR Pathway.
Author: Li, Yazhou|Liu, Yang|Shi, Feiyu|Cheng, Liang|She, Junjun
PMID: 27712585
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Oct 25;19(10):1191-1196.
Title: [Research status quo and progression in targeted therapy for advanced gastric cancer].
Author: Feng, Rui|Zhang, Xiaotian|Yang, Sheng
PMID: 27781258
Journal: Oncotarget. 2016 Dec 27;7(52):86161-86173.
Title: Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling.
Author: Dou, Ning|Yu, Shijun|Ye, Xiaojuan|Yang, Dong|Li, Yandong|Gao, Yong
PMID: 27863387
Journal: Evid Based Complement Alternat Med. 2016;2016:9406758.
Title: Autophagy Protects from Raddeanin A-Induced Apoptosis in SGC-7901 Human Gastric Cancer Cells.
Author: Teng, Yu-Hao|Li, Jie-Pin|Liu, Shen-Lin|Zou, Xi|Fang, Liang-Hua|Zhou, Jin-Yong|Wu, Jian|Xi, Song-Yang|Chen, Yan|Zhang, Ying-Ying|Xu, Song|Wang, Rui-Ping
PMID: 27974905
Journal: J Cancer. 2016 Oct 25;7(15):2173-2178.
Title: To Excavate Biomarkers Predictive of the Response for Capecitabine plus RAD001 through Nanostring-Based Multigene Assay in Advanced Gastric Cancer Patients.
Author: Lee, Hansang|Lee, Jeeyun|Sohn, Insuk|Park, Se Hoon|Park, Joon Oh|Park, Young Suk|Kim, Kyoung-Mee|Kang, Won Ki|Kim, Seung Tae
PMID: 27994652
Journal: PLoS One. 2016 Dec 22;11(12):e0168085.
Title: Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric Cancer.
Author: Cao, Guo-Dong|Xu, Xing-Yu|Zhang, Jia-Wei|Chen, Bo|Xiong, Mao-Ming
PMID: 28005970
Journal: Oncol Res. 2016 Oct 27;24(6):487-494.
Title: CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line.
Author: Zhang, Jian|Shi, ZhenFeng|Huang, JinXing|Zou, XiaoGuang
PMID: 28281969
Journal: Mol Cell Biochem. 2017 Jan;424(1-2):173-183.
Title: Akt/AMPK/mTOR pathway was involved in the autophagy induced by vitamin E succinate in human gastric cancer SGC-7901 cells.
Author: Yu, Yang|Hou, Liying|Song, Huacui|Xu, Peixiang|Sun, Yue|Wu, Kun
PMID: 27796683
Journal: Int J Pharm. 2017 Jan 30;517(1-2):25-34.
Title: Fabrication of self-assembled chitosan-dispersed LDL nanoparticles for drug delivery with a one-step green method.
Author: Tian, Jing|Xu, Shasha|Deng, Hongbing|Song, Xinxing|Li, Xiujuan|Chen, Jiajia|Cao, Feng|Li, Bin
PMID: 27845214
Journal: Ann Oncol. 2017 Mar 1;28(3):547-554.
Title: Rapamycin-insensitive companion of mTOR (RICTOR) amplification defines a subset of advanced gastric cancer and is sensitive to AZD2014-mediated mTORC1/2 inhibition.
Author: Kim, S T|Kim, S Y|Klempner, S J|Yoon, J|Kim, N|Ahn, S|Bang, H|Kim, K-M|Park, W|Park, S H|Park, J O|Park, Y S|Lim, H Y|Lee, S H|Park, K|Kang, W K|Lee, J
PMID: 28028034
Journal: Free Radic Biol Med. 2017 May;106:24-37.
Title: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author: Wang, Gangyang|Zhang, Tao|Sun, Wei|Wang, Hongsheng|Yin, Fei|Wang, Zhuoying|Zuo, Dongqing|Sun, Mengxiong|Zhou, Zifei|Lin, Binhui|Xu, Jing|Hua, Yingqi|Li, Haoqing|Cai, Zhengdong
PMID: 28188923
Journal: Sci Rep. 2017 Feb 20;7:42876.
Title: DDX5 promotes gastric cancer cell proliferation in vitro and in vivo through mTOR signaling pathway.
Author: Du, Cheng|Li, Dan-Qi|Li, Na|Chen, Li|Li, Shi-Sen|Yang, Yang|Hou, Ming-Xiao|Xie, Man-Jiang|Zheng, Zhen-Dong
PMID: 28216662
Journal: Oncol Rep. 2017 Apr;37(4):2441-2448.
Title: MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3.
Author: Liu, Yanqi|Sun, Yanhong|Zhao, Aizhen
PMID: 28260021
Journal: Clin Exp Pharmacol Physiol. 2017 Jun;44(6):613-622.
Title: Gastric cancer management: Kinases as a target therapy.
Author: Farran, Batoul|Muller, Susanne|Montenegro, Raquel C
PMID: 28271563
Journal: Gastric Cancer. 2017 Nov;20(6):948-959.
Title: Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells.
Author: Chivu-Economescu, Mihaela|Dragu, Denisa L|Necula, Laura G|Matei, Lilia|Enciu, Ana Maria|Bleotu, Coralia|Diaconu, Carmen C
PMID: 28299464
Journal: Int J Oncol. 2017 May;50(5):1501-1512.
Title: FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Author: Huang, Tingting|Wang, Lei|Liu, Dian|Li, Piao|Xiong, Huihua|Zhuang, Liang|Sun, Li|Yuan, Xianglin|Qiu, Hong
PMID: 28339036
Journal: Arch Toxicol. 2017 Oct;91(10):3341-3364.
Title: Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.
Author: Chang, Chia-Ting|Hseu, You-Cheng|Thiyagarajan, Varadharajan|Lin, Kai-Yuan|Way, Tzong-Der|Korivi, Mallikarjuna|Liao, Jiuun-Wang|Yang, Hsin-Ling
PMID: 28374157
Journal: Front Cell Infect Microbiol. 2017 Mar 28;7:92.
Title: Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1alpha to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells.
Author: Canales, Jimena|Valenzuela, Manuel|Bravo, Jimena|Cerda-Opazo, Paulina|Jorquera, Carla|Toledo, Hector|Bravo, Denisse|Quest, Andrew F G
PMID: 28401064
Journal: Mol Cancer. 2017 Apr 26;16(1):83.
Title: Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer.
Author: Geng, Qirong|Liu, Jianjun|Gong, Zhaohui|Chen, Shangxiang|Chen, Shuai|Li, Xiaoxing|Lu, Yue|Zhu, Xiaofeng|Lin, Hui-Kuan|Xu, Dazhi
PMID: 28446188
Journal: J Transl Med. 2017 May 1;15(1):92.
Title: Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.
Author: Chen, Ina|Mathews-Greiner, Lesley|Li, Dandan|Abisoye-Ogunniyan, Abisola|Ray, Satyajit|Bian, Yansong|Shukla, Vivek|Zhang, Xiaohu|Guha, Raj|Thomas, Craig|Gryder, Berkley|Zacharia, Athina|Beane, Joal D|Ravichandran, Sarangan|Ferrer, Marc|Rudloff, Udo
PMID: 28460635
Journal: J Ethnopharmacol. 2017 Jun 9;205:147-157.
Title: Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer.
Author: Wang, Haibo|Tao, Lide|Ni, Tengyang|Gu, Hao|Jin, Feng|Dai, Xiaojun|Feng, Jun|Ding, Yanbing|Xiao, Weiming|Guo, Shiyu|Hisamitsu, Tadashi|Qian, Yayun|Liu, Yanqing
PMID: 28476678
Journal: Oncotarget. 2017 Jul 18;8(29):48253-48262.
Title: Efficacy and safety of different molecular targeted agents based on chemotherapy for gastric cancer patients treatment: a network meta-analysis.
Author: Ren, Zheng|Sun, Jinping|Sun, Xinfang|Hou, Hongtao|Li, Ke|Ge, Quanxing
PMID: 28477027
Journal: Phytomedicine. 2017 May 15;28:10-18.
Title: Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.
Author: Li, Chuan|Wang, Yihai|Wang, Chunhua|Yi, Xiaomin|Li, Mingya|He, Xiangjiu
PMID: 28478808
Journal: Sci Rep. 2017 May 8;7(1):1526.
Title: In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies.
Author: Pinto, Joseph A|Rolfo, Christian|Raez, Luis E|Prado, Alexandra|Araujo, Jhajaira M|Bravo, Leny|Fajardo, Williams|Morante, Zaida D|Aguilar, Alfredo|Neciosup, Silvia P|Mas, Luis A|Bretel, Denisse|Balko, Justin M|Gomez, Henry L
PMID: 28484222
Journal: Oncol Rep. 2017 Jun;37(6):3459-3466.
Title: Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells.
Author: Li, Wei|Zhou, Ying|Yang, Jin|Li, Haining|Zhang, Huanhuan|Zheng, Ping
PMID: 28498433
Journal: Oncol Rep. 2017 Jun;37(6):3590-3596.
Title: MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.
Author: Qiu, Yun-Tan|Wang, Wen-Jun|Zhang, Bing|Mei, Li-Li|Shi, Zhi-Zhou
PMID: 28498460
Journal: Cell Signal. 2017 Aug;36:222-229.
Title: Inhibition of cell proliferation and induction of autophagy by KDM2B/FBXL10 knockdown in gastric cancer cells.
Author: Zhao, Erhu|Tang, Chunling|Jiang, Xiaolan|Weng, Xiong|Zhong, Xiaoxia|Zhang, Dunke|Hou, Jianbing|Wang, Feng|Huang, Mengying|Cui, Hongjuan
PMID: 28506929
Journal: Oncotarget. 2017 Jul 11;8(28):45793-45806.
Title: Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance.
Author: Liu, Wenhu|Chang, Jinxia|Liu, Mingwei|Yuan, Jiangbei|Zhang, Jinqiang|Qin, Jun|Xia, Xuefeng|Wang, Yi
PMID: 28507275
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Autophagy. 2017 Aug 3;13(8):1404-1419.
Title: Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death.
Author: Leng, Zhi Gen|Lin, Shao Jian|Wu, Ze Rui|Guo, Yu Hang|Cai, Lin|Shang, Han Bing|Tang, Hao|Xue, Ya Jun|Lou, Mei Qing|Zhao, Wenxiu|Le, Wei-Dong|Zhao, Wei Guo|Zhang, Xun|Wu, Zhe Bao
PMID: 28613975
Journal: Br J Cancer. 2017 Aug 8;117(4):525-534.
Title: MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer.
Author: Zhang, P|Tang, W M|Zhang, H|Li, Y Q|Peng, Y|Wang, J|Liu, G N|Huang, X T|Zhao, J J|Li, G|Li, A M|Bai, Y|Chen, Y|Ren, Y X|Li, G X|Wang, Y D|Liu, S D|Wang, J D
PMID: 28632723
Journal: Cell Physiol Biochem. 2017;42(3):1025-1036.
Title: Knockdown of ARK5 Expression Suppresses Invasion and Metastasis of Gastric Cancer.
Author: Chen, Dehu|Liu, Guiyuan|Xu, Ning|You, Xiaolan|Zhou, Haihua|Zhao, Xiaojun|Liu, Qinghong
PMID: 28662499
Journal: Technol Cancer Res Treat. 2017 Jan 1:1533034617717863.
Title: miR-7 Increases Cisplatin Sensitivity of Gastric Cancer Cells Through Suppressing mTOR.
Author: Xu, Ning|Lian, Yan-Jun|Dai, Xiang|Wang, Yuan-Jie
PMID: 28693382
Journal: Int J Oncol. 2017 Sep;51(3):967-974.
Title: Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling.
Author: Lee, Harry|Saini, Nipun|Parris, Amanda B|Zhao, Ming|Yang, Xiaohe
PMID: 28713919
Journal: Zhonghua Zhong Liu Za Zhi. 2017 Jul 23;39(7):490-496.
Title: [Curcumin induces apoptosis and protective autophagy in human gastric cancer cells with different degree of differentiation].
Author: Li, W|Zhou, Y|Yang, J|Zhang, H H|Zhao, S L|Zhang, T|Huo, J|Zheng, P
PMID: 28728293
Journal: J Gastrointest Oncol. 2017 Jun;8(3):418-429.
Title: Biologic therapy in esophageal and gastric malignancies: current therapies and future directions.
Author: Samson, Pamela|Lockhart, A Craig
PMID: 28736629
Journal: Expert Opin Investig Drugs. 2017 Sep;26(9):1007-1017.
Title: Angiogenesis inhibitors in early development for gastric cancer.
Author: Pinto, Mauricio P|Owen, Gareth I|Retamal, Ignacio|Garrido, Marcelo
PMID: 28770623
Journal: Autophagy. 2017 Aug 3;13(8):1404-1419.
Title: Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death.
Author: Leng, Zhi Gen|Lin, Shao Jian|Wu, Ze Rui|Guo, Yu Hang|Cai, Lin|Shang, Han Bing|Tang, Hao|Xue, Ya Jun|Lou, Mei Qing|Zhao, Wenxiu|Le, Wei-Dong|Zhao, Wei Guo|Zhang, Xun|Wu, Zhe Bao
PMID: 28789388
Journal: Cancer Med. 2017 Oct;6(10):2331-2346.
Title: CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Author: Sun, Yi|Jiang, Yingming|Huang, Jintuan|Chen, Hao|Liao, Yi|Yang, Zuli
PMID: 28857517
Journal: Am J Transl Res. 2017 Sep 15;9(9):4317-4330. eCollection 2017.
Title: Targeting mTORC2 component rictor inhibits cell proliferation and promotes apoptosis in gastric cancer.
Author: Bian, Yu-Hai|Xu, Jia|Zhao, Wen-Yi|Zhang, Zi-Zhen|Tu, Lin|Cao, Hui|Zhang, Zhi-Gang
PMID: 28979705
Journal: Biomed Pharmacother. 2017 Dec;96:634-641.
Title: MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer.
Author: Xu, Song|Ge, Jingping|Zhang, Zhengyu|Zhou, Wenquan
PMID: 29035829
Journal: Oncotarget. 2017 Jul 22;8(41):69888-69905.
Title: Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients.
Author: Kim, Yoonjung|Cho, Mee-Yon|Kim, Juwon|Kim, Sung Nam|Oh, Seoung Chul|Lee, Kyung-A
PMID: 29050249
Journal: Iran J Basic Med Sci. 2017 Sep;20(9):990-995.
Title: Apatinib has anti-tumor effects and induces autophagy in colon cancer cells.
Author: Lu, Wu|Ke, He|Qianshan, Ding|Zhen, Wang|Guoan, Xiang|Honggang, Yu
PMID: 29085592
Journal: Biomed Res Int. 2017;2017:7869802.
Title: Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer.
Author: Carlomagno, Nicola|Incollingo, Paola|Tammaro, Vincenzo|Peluso, Gaia|Rupealta, Niccolo|Chiacchio, Gaetano|Sandoval Sotelo, Maria Laura|Minieri, Gianluca|Pisani, Antonio|Riccio, Eleonora|Sabbatini, Massimo|Bracale, Umberto Marcello|Calogero, Armando|Dodaro,
PMID: 29094049
Journal: Dig Dis Sci. 2017 Dec;62(12):3426-3437.
Title: The GAS5/miR-222 Axis Regulates Proliferation of Gastric Cancer Cells Through the PTEN/Akt/mTOR Pathway.
Author: Li, Yanhua|Gu, Junjiao|Lu, Hong
PMID: 29098549
Journal: Oncotarget. 2017 Jul 22;8(44):76458-76467.
Title: Effects of targeting SLC1A5 on inhibiting gastric cancer growth and tumor development in vitro and in vivo.
Author: Lu, Jian|Chen, Min|Tao, Zhenhua|Gao, Sumeng|Li, Yang|Cao, Yu|Lu, Chun|Zou, Xiaoping
PMID: 29100325
Journal: Arch Med Sci. 2017 Oct;13(6):1262-1268.
Title: Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas.
Author: Chiappini, Paula Blandina Ola|de Medeiros, Ivan Ucella Dantas|Lima, Luiz Guilherme Cenaglia|Fregnani, Jose Humberto|Nonogaki, Suely|da Costa, Wilson Luiz Jr|Coimbra, Felipe Jose Fernandez|Silva, Milton Jose de Barros E|de Mello, Celso Abdon Lopes|Pinto, C
PMID: 29181056
Journal: Oncotarget. 2017 Jul 17;8(55):93476-93491.
Title: Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway.
Author: Li, Chengyun|Liang, Geyu|Yang, Sheng|Sui, Jing|Yao, Wenzhuo|Shen, Xian|Zhang, Yanqiu|Peng, Hui|Hong, Weiwei|Xu, Siyi|Wu, Wenjuan|Ye, Yancheng|Zhang, Zhiyi|Zhang, Wenhua|Yin, Lihong|Pu, Yuepu
PMID: 29212166
Journal: Anticancer Drugs. 2017 Dec 5.
Title: Mangiferin prevents the growth of gastric carcinoma by blocking the PI3K-Akt signalling pathway.
Author: Du, Min|Wen, Gang|Jin, Juan|Chen, Yuanguang|Cao, Jun|Xu, Aman
PMID: 29215373
Journal: J Biosci. 2017 Dec;42(4):547-554.
Title: Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway.
Author: Feng, Li-Min|Wang, Xue-Feng|Huang, Qing-Xian
PMID: 29229873
Journal: BMC Cancer. 2017 Dec 12;17(1):841.
Title: Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients.
Author: Cao, Guo-Dong|Chen, Ke|Chen, Bo|Xiong, Mao-Ming
PMID: 29233126
Journal: Klin Onkol. 2017 Winter;30(Supplementum3):50-54.
Title: [Checkpoint Inhibitors in the Treatment of Upper Gastrointestinal Tract Tumors].
Author: Obermannova, R
PMID: 29239193
Journal: J BUON. 2017 Nov-Dec;22(6):1488-1493.
Title: Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.
Author: Qi, Lei|Sun, Kewen|Zhuang, Yun|Yang, Jing|Chen, Jianping
PMID: 29332342
Journal: J Cell Physiol. 2018 Jun;233(6):4634-4642.
Title: Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling.
Author: Fu, Hongbing|Wang, Changming|Yang, Dejun|Wei, Ziran|Xu, Jiapeng|Hu, Zunqi|Zhang, Yu|Wang, Weimin|Yan, Ronglin|Cai, Qingping
PMID: 28926094
Journal: Cell Prolif. 2018 Apr;51(2):e12399.
Title: Enhanced gastric cancer growth potential of mesenchymal stem cells derived from gastric cancer tissues educated by CD4(+) T cells.
Author: Xu, Rongman|Zhao, Xiangdong|Zhao, Yuanyuan|Chen, Bin|Sun, Li|Xu, Changgen|Shen, Bo|Wang, Mei|Xu, Wenrong|Zhu, Wei
PMID: 29057538
Journal: Cancer Sci. 2018 Jan;109(1):65-73.
Title: Increased T-helper 17 cell differentiation mediated by exosome-mediated microRNA-451 redistribution in gastric cancer infiltrated T cells.
Author: Liu, Feng|Bu, Zhouyan|Zhao, Feng|Xiao, Daping
PMID: 29059496
Journal: DNA Cell Biol. 2018 Jan;37(1):38-45.
Title: miR-21 Inhibitors Modulate Biological Functions of Gastric Cancer Cells via PTEN/PI3K/mTOR Pathway.
Author: Wang, Ping|Guan, Qunye|Zhou, Dongmei|Yu, Ze|Song, Yaobo|Qiu, Wensheng
PMID: 29185784
Journal: Acta Pharmacol Sin. 2018 Apr;39(4):642-648.
Title: Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of raddeanin A against human breast cancer cells in vitro.
Author: Guan, Yi-di|Jiang, Shi-Long|Yu, Pian|Wen, Mei|Zhang, Yi|Xiao, Song-Shu|Xu, Xiao-Jun|Cheng, Yan
PMID: 29239350
Journal: Cancer Biomark. 2018 Feb 14;21(3):731-741.
Title: EGFR and AKT1 overexpression are mutually exclusive and associated with a poor survival in resected gastric adenocarcinomas.
Author: Petrini, Iacopo|Lencioni, Monica|Vasile, Enrico|Fornaro, Lorenzo|Belluomini, Lorenzo|Pasquini, Giulia|Ginocchi, Laura|Caparello, Chiara|Musettini, Gianna|Vivaldi, Caterina|Caponi, Sara|Ricci, Sergio|Proietti, Agenese|Fontanini, Gabriella|Naccarato, Antoni
PMID: 29278885
Journal: Sci Rep. 2018 Jan 10;8(1):397.
Title: Correlation of Gli1 and HER2 expression in gastric cancer: Identification of novel target.
Author: Shao, Xinyu|Kuai, Xiaoyi|Pang, Zhi|Zhang, Liping|Wu, Longyun|Xu, Lijuan|Zhou, Chunli
PMID: 29321573
Journal: Mol Cancer. 2018 Jan 12;17(1):6.
Title: STAT3-induced lncRNA HAGLROS overexpression contributes to the malignant progression of gastric cancer cells via mTOR signal-mediated inhibition of autophagy.
Author: Chen, Jin-Fei|Wu, Peng|Xia, Rui|Yang, Jian|Huo, Xin-Ying|Gu, Dong-Ying|Tang, Cui-Ju|De, Wei|Yang, Fen
PMID: 29329543
Journal: Biochem Biophys Res Commun. 2018 Feb 5;496(2):475-481.
Title: ESCO2 knockdown inhibits cell proliferation and induces apoptosis in human gastric cancer cells.
Author: Chen, Hongmei|Zhang, Lei|He, Wenting|Liu, Tao|Zhao, Yang|Chen, Hao|Li, Yumin
PMID: 29330052
Journal: Cell Death Dis. 2018 Jan 26;9(2):123.
Title: Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway.
Author: Chen, Dongshao|Lin, Xiaoting|Zhang, Cheng|Liu, Zhentao|Chen, Zuhua|Li, Zhongwu|Wang, Jingyuan|Li, Beifang|Hu, Yanting|Dong, Bin|Shen, Lin|Ji, Jiafu|Gao, Jing|Zhang, Xiaotian
PMID: 29374144
Journal: Cell Discov. 2018 Jan 9;4:1.
Title: TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling.
Author: Kawasaki, Natsumi|Isogaya, Kazunobu|Dan, Shingo|Yamori, Takao|Takano, Hiroshi|Yao, Ryoji|Morishita, Yasuyuki|Taguchi, Luna|Morikawa, Masato|Heldin, Carl-Henrik|Noda, Tetsuo|Ehata, Shogo|Miyazono, Kohei|Koinuma, Daizo
PMID: 29423269
Journal: J Hematol Oncol. 2018 Feb 13;11(1):20.
Title: Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer.
Author: Chen, Zuhua|Huang, Wenwen|Tian, Tiantian|Zang, Wanchun|Wang, Jingyuan|Liu, Zhentao|Li, Zhongwu|Lai, Yumei|Jiang, Zhi|Gao, Jing|Shen, Lin
PMID: 29433585
Journal: Oncol Lett. 2018 Mar;15(3):3127-3132.
Title: Effect of silencing colon cancer-associated transcript 2 on the proliferation, apoptosis and autophagy of gastric cancer BGC-823 cells.
Author: Yu, Zhao-Yan|Wang, Zi|Lee, Ke-Yue|Yuan, Ping|Ding, Jie
PMID: 29435046
Journal: Oncotarget. 2017 Dec 20;9(4):4886-4896.
Title: MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway.
Author: Tian, Lei|Zhao, Zhifeng|Xie, Ling|Zhu, JinPeng
PMID: 29435149
Journal: Int J Mol Med. 2018 May;41(5):2755-2763.
Title: LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3beta signaling.
Author: Qiu, Yan-Song|Jiang, Ning-Ning|Zhou, Yan|Yu, Kuai-Yun|Gong, Hong-Yan|Liao, Guang-Jun
PMID: 29436606
Journal: Clin Transl Med. 2018 Feb 22;7(1):7.
Title: Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk.
Author: Li, Dandan|Lo, Winifred|Rudloff, Udo
PMID: 29468433
Journal: Sci Rep. 2018 Feb 26;8(1):3593.
Title: Indomethacin Disrupts Autophagic Flux by Inducing Lysosomal Dysfunction in Gastric Cancer Cells and Increases Their Sensitivity to Cytotoxic Drugs.
Author: Vallecillo-Hernandez, Jorge|Barrachina, Maria Dolores|Ortiz-Masia, Dolores|Coll, Sandra|Esplugues, Juan Vicente|Calatayud, Sara|Hernandez, Carlos
PMID: 29483523
Journal: Oncol Lett. 2018 Apr;15(4):4143-4150.
Title: Autophagy flux inhibition augments gastric cancer resistance to the anti-human epidermal growth factor receptor 2 antibody trastuzumab.
Author: Ye, Hua|Chai, Xuyu|Wang, Xiaoyu|Zheng, Qi|Zheng, Dingcheng|Wu, Feng|Zheng, Cheng|Chen, Ping
PMID: 29541179
Journal: Mol Cancer Ther. 2018 Jun;17(6):1259-1270.
Title: Acquired Resistance to a MET Antibody In Vivo Can Be Overcome by the MET Antibody Mixture Sym015.
Author: Pollmann, Sofie Ellebaek|Calvert, Valerie S|Rao, Shruti|Boca, Simina M|Madhavan, Subha|Horak, Ivan D|Kjaer, Andreas|Petricoin, Emanuel F|Kragh, Michael|Poulsen, Thomas Tuxen
PMID: 29545332
Journal: Oncol Rep. 2018 May;39(5):2450.
Title: [Corrigendum] RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer.
Author: Wang, Wenwen|Liu, Juan|Qi, Jianni|Zhang, Junyong|Zhu, Qiang|Qin, Chengyong
PMID: 29565451
Journal: World J Gastroenterol. 2018 Mar 21;24(11):1206-1215.
Title: Three-microRNA signature identified by bioinformatics analysis predicts prognosis of gastric cancer patients.
Author: Zhang, Cheng|Zhang, Chun-Dong|Ma, Ming-Hui|Dai, Dong-Qiu
PMID: 29568201
Journal: Int J Oncol. 2018 Jun;52(6):2011-2020.
Title: PPP2R2D, a regulatory subunit of protein phosphatase 2A, promotes gastric cancer growth and metastasis via mechanistic target of rapamycin activation.
Author: Yu, Shijun|Li, Li|Wu, Qiong|Dou, Ning|Li, Yandong|Gao, Yong
PMID: 29568966
Journal: Oncol Rep. 2018 Jun;39(6):2595-2603.
Title: Cucurbitacin D impedes gastric cancer cell survival via activation of the iNOS/NO and inhibition of the Akt signalling pathway.
Author: Zhang, Yan Zhen|Wang, Chun Feng|Zhang, Lian Feng
PMID: 29658590
Journal: J Cell Biochem. 2018 Aug;119(8):6905-6913.
Title: Long non-coding RNA SNHG14 contributes to gastric cancer development through targeting miR-145/SOX9 axis.
Author: Liu, Zhao|Yan, Yan|Cao, Sizhe|Chen, Yi
PMID: 29667771
Journal: Oncologist. 2018 Sep;23(9):1092-1102.
Title: Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab.
Author: Diaz-Serrano, Asuncion|Angulo, Barbara|Dominguez, Carolina|Pazo-Cid, Roberto|Salud, Antonieta|Jimenez-Fonseca, Paula|Leon, Ana|Galan, Maria Carmen|Alsina, Maria|Rivera, Fernando|Plaza, J Carlos|Paz-Ares, Luis|Lopez-Rios, Fernando|Gomez-Martin, Carlos
PMID: 29700210
Journal: Iran Biomed J. 2018 Apr 29.
Title: PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer
Author: Iranpour, Mostafa|Nourian, Mahyar|Saffari, Sana|Samizadeh, Esmaeil|Mirghafori, Mahdieh|Iravani, Shahrokh|Ghafouri-Fard, Soudeh
PMID: 29704890
Journal: J Cancer. 2018 Apr 6;9(8):1448-1454.
Title: Genetic Variants Within MTORC1 Genes Predict Gastric Cancer Prognosis in Chinese Populations.
Author: Xue, Wenji|Wang, Mengyun|Zhang, Li|Gu, Jianchun|Zhu, Xueru|Wang, Yiwei|Wang, Ruifen|Wang, Lifeng|Wang, Weiye|Wang, Xue-Feng|Mei, Jia-Wei|Zheng, Leizhen|Zhu, Mei-Ling
PMID: 29721055
Journal: Am J Transl Res. 2018 Apr 15;10(4):1229-1236. eCollection 2018.
Title: Rab5a suppresses autophagy to promote drug resistance in cancer cells.
Author: Xu, Wenxia|Shi, Qiqi|Qian, Xiaoling|Zhou, Bingluo|Xu, Jinye|Zhu, Liyuan|Feng, Lifeng|Jin, Hongchuan|Wang, Xian
PMID: 29736216
Journal: Mol Med Rep. 2018 Jul;18(1):587-594.
Title: Helicobacter pylori infection impairs gastric epithelial barrier function via microRNA100mediated mTOR signaling inhibition.
Author: Hu, Guimei|Guo, Lihua|Ye, Guoliang
PMID: 29749451
Journal: J Pharm Pharmacol. 2018 Aug;70(8):1048-1058.
Title: Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells.
Author: Bai, Xin-Yu|Liu, Yuan-Gui|Song, Wu|Li, Ying-Ying|Hou, Dong-Shun|Luo, Hao-Ming|Liu, Ping
PMID: 29770446
Journal: Biochem Biophys Res Commun. 2018 Jul 2;501(4):1068-1073.
Title: MiR-616-3p promotes angiogenesis and EMT in gastric cancer via the PTEN/AKT/mTOR pathway.
Author: Wu, Zhen-Hua|Lin, Chen|Liu, Chen-Chen|Jiang, Wei-Wei|Huang, Ming-Zhu|Liu, Xin|Guo, Wei-Jian
PMID: 29777710
Journal: Gene. 2018 Sep 5;670:130-135.
Title: Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.
Author: Ge, Yuqiu|Liu, Hanting|Qiu, Xiaonan|Ma, Gaoxiang|Wang, Haixiao|Du, Mulong|Wang, Meilin|Zhao, Qinghong|Tao, Guoquan|Chu, Haiyan|Zhang, Zhengdong
PMID: 29802999
Journal: Evid Based Complement Alternat Med. 2018 May 2;2018:7802639.
Title: Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer.
Author: Liu, Xinkui|Wu, Jiarui|Zhang, Dan|Wang, Kaihuan|Duan, Xiaojiao|Meng, Ziqi|Zhang, Xiaomeng
PMID: 29853970
Journal: Biomed Pharmacother. 2018 Sep;105:326-333.
Title: Downregulation of circular RNA hsa_circ_0001649 indicates poor prognosis for retinoblastoma and regulates cell proliferation and apoptosis via AKT/mTOR signaling pathway.
Author: Xing, Lichen|Zhang, Leiming|Feng, Yali|Cui, Zhe|Ding, Lin
PMID: 29864621
Journal: Biomed Pharmacother. 2018 Jul;103:1688-1700.
Title: Current and future biomarkers in gastric cancer.
Author: Abbas, Muhammad|Faggian, Alessia|Sintali, Dahiru Nasiru|Khan, Ghulam Jilany|Naeem, Shagufta|Shi, Meiqi|Dingding, Chen
PMID: 29864959
Journal: Onco Targets Ther. 2018 May 22;11:3025-3033.
Title: LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway.
Author: Ke, Jing|Ma, Peng|Chen, Jinpeng|Qin, Jun|Qian, Haixin
PMID: 29872314
Journal: Biochem Biophys Res Commun. 2018 Sep 3;503(1):391-396.
Title: Ataxin-3 promotes testicular cancer cell proliferation by inhibiting anti-oncogene PTEN.
Author: Shi, Zhan|Chen, Jiaxin|Zhang, Xiangmin|Chu, Jian|Han, Zhitao|Xu, Da|Gan, Sishun|Pan, Xiuwu|Ye, Jianqing|Cui, Xingang
PMID: 29902454
Journal: Oncol Lett. 2018 Jul;16(1):594-602.
Title: Small interfering RNA-mediated knockdown of fatty acid synthase attenuates the proliferation and metastasis of human gastric cancer cells via the mTOR/Gli1 signaling pathway.
Author: Sun, Liang|Yao, Yizhou|Pan, Guofeng|Zhan, Shenghua|Shi, Weiqiang|Lu, Ting|Yuan, Jinfeng|Tian, Kangjun|Jiang, Linhua|Song, Shiduo|Zhu, Xinguo|He, Songbing
PMID: 29928446
Journal: Neoplasma. 2018 Sep 19;65(5):693-700.
Title: Anticancer effect of YWHAZ silencing via inducing apoptosis and autophagy in gastric cancer cells.
Author: Guo, F|Jiao, D|Sui, G Q|Sun, L N|Gao, Y J|Fu, Q F|Jin, C X
PMID: 29940752
Journal: J Cell Biochem. 2018 Jun 28.
Title: Silencing forkhead box M1 promotes apoptosis and autophagy through SIRT7/mTOR/IGF2 pathway in gastric cancer cells.
Author: Yu, Wei|Cui, Xiaofeng|Wan, Zhongyi|Yu, Yanhui|Liu, Xiumin|Jin, Lifang
PMID: 29953672
Journal: Exp Cell Res. 2018 Sep 15;370(2):283-291.
Title: SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling.
Author: Seah, Kwi Shan|Loh, Jian Yun|Nguyen, Thi Thuy Trang|Tan, Hwei Ling|Hutchinson, Paul E|Lim, Kim Kiat|Dymock, Brian W|Long, Yun Chau|Lee, Edmund Jon Deoon|Shen, Han-Ming|Chen, Ee Sin
PMID: 29959912
Journal: Int J Cancer. 2018 Jul 6.
Title: Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.
Author: Cheng, Lei|Qiu, Lixin|Zhang, Ruoxin|Qian, Danwen|Wang, Mengyun|Sun, Menghong|Zhu, Xiaodong|Wang, Yanong|Guo, Weijian|Wei, Qingyi
PMID: 29978580
Journal: Int J Biol Sci. 2018 Jun 3;14(9):1054-1066.
Title: CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer.
Author: Xu, Wenxia|Wei, Qi|Han, Mengjiao|Zhou, Bingluo|Wang, Hanying|Zhang, Jianbing|Wang, Qiang|Sun, Jie|Feng, Lifeng|Wang, Shouyu|Ye, Yang|Wang, Xian|Zhou, Jianwei|Jin, Hongchuan
PMID: 29989092
Journal: Arch Pharm Res. 2018 Jul 10. pii: 10.1007/s12272-018-1049-8.
Title: Autophagy plays a protective role against apoptosis induced by toxicarioside N via the Akt/mTOR pathway in human gastric cancer SGC-7901 cells.
Author: Zhao, Huan-Ge|Zhou, Song-Lin|Lin, Ying-Ying|Wang, Hua|Dai, Hao-Fu|Huang, Feng-Ying
PMID: 29992400
Journal: Int J Biochem Cell Biol. 2018 Sep;102:128-137.
Title: Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor.
Author: Lee, Suk-Young|Na, Yoo Jin|Jeong, Yoon A|Kim, Jung Lim|Oh, Sang Cheul|Lee, Dae-Hee
PMID: 30044964
Journal: Mol Med Rep. 2018 Sep;18(3):3429-3436.
Title: Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Author: Zhang, Xiu-Rong|Wang, Shi-Yao|Sun, Wen|Wei, Chao
PMID: 30066879
Journal: Nutrients. 2018 Aug 8;10(8). pii: nu10081043.
Title: Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.
Author: Lee, Ho Jeong|Venkatarame Gowda Saralamma, Venu|Kim, Seong Min|Ha, Sang Eun|Raha, Suchismita|Lee, Won Sup|Kim, Eun Hee|Lee, Sang Joon|Heo, Jeong Doo|Kim, Gon Sup
PMID: 30096805
Journal: Cell Physiol Biochem. 2018;48(6):2231-2246.
Title: Anti-Cancer Effects of Radix Angelica Sinensis (Danggui) and N-Butylidenephthalide on Gastric Cancer: Implications for REDD1 Activation and mTOR Inhibition.
Author: Liao, Kuan-Fu|Chiu, Tsung-Lang|Huang, Sung-Ying|Hsieh, Teng-Fu|Chang, Shu-Fang|Ruan, Jhen-Wei|Chen, Shee-Ping|Pang, Cheng-Yoong|Chiu, Sheng-Chun
PMID: 30114701
Journal: Biomed Pharmacother. 2018 Oct;106:1300-1306.
Title: Xanthohumol induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI3K/Akt/mTOR-kinase in human gastric cancer cells.
Author: Guo, Dongli|Zhang, Baogui|Liu, Shiqi|Jin, Meng
PMID: 30119200
Journal: Med Sci Monit. 2018 Aug 27;24:5960-5972.
Title: MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2).
Author: Li, Na|Han, Mei|Zhou, Ning|Tang, Yong|Tang, Xu-Shan
PMID: 30147110
Journal: Braz J Med Biol Res. 2018 Aug 16;51(10):e6839.
Title: Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1.
Author: Liu, Pei|Zhang, Mingming|Niu, Qinghui|Zhang, Fengjuan|Yang, Yuling|Jiang, Xiangjun
PMID: 30156609
Journal: Cell Death Dis. 2018 Sep 11;9(9):928.
Title: Gastric cancer mesenchymal stem cells derived IL-8 induces PD-L1 expression in gastric cancer cells via STAT3/mTOR-c-Myc signal axis.
Author: Sun, Li|Wang, Qianqian|Chen, Bin|Zhao, Yuanyuan|Shen, Bo|Wang, Hua|Xu, Jing|Zhu, Miaolin|Zhao, Xiangdong|Xu, Changgen|Chen, Zhihong|Wang, Mei|Xu, Wenrong|Zhu, Wei
PMID: 30206229
Journal: Pharmazie. 2018 Oct 1;73(10):594-597.
Title: Andrographolide inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through LKB1-AMPK-dependent signaling pathways.
Author: Wu, Bo|Chen, Xi|Zhou, Ying|Hu, Pingjun|Wu, Dan|Zheng, Guodong|Cai, Yi
PMID: 30223924
Journal: Oncol Lett. 2018 Oct;16(4):4863-4870.
Title: Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis.
Author: Pan, Xuan|Ji, Xiaozhi|Zhang, Renmin|Zhou, Zhaofei|Zhong, Yuejiao|Peng, Wei|Sun, Ning|Xu, Xinyu|Xia, Lei|Li, Pansong|Lu, Jianwei|Tu, Jing
PMID: 30250552
Journal: Oncol Lett. 2018 Oct;16(4):5355-5360.
Title: MicroRNA-99b promotes Helicobacter pylori-induced autophagyand suppresses carcinogenesis by targeting mTOR.
Author: Yang, Liu|Li, Cong|Jia, Yujie
PMID: 30250606
Journal: Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title: F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author: Yao, Hui|Su, Song|Xia, Dong|Wang, Mingming|Li, Zonglin|Chen, Wangsheng|Ren, Lei|Xu, Liang
PMID: 30257389
Journal: Gastric Cancer. 2018 Sep 28. pii: 10.1007/s10120-018-0880-4.
Title: EBV-associated gastric cancer evades T-cell immunity by PD-1/PD-L1 interactions.
Author: Sasaki, Sho|Nishikawa, Jun|Sakai, Kohei|Iizasa, Hisashi|Yoshiyama, Hironori|Yanagihara, Masashi|Shuto, Takuya|Shimokuri, Kanami|Kanda, Teru|Suehiro, Yutaka|Yamasaki, Takahiro|Sakaida, Isao
PMID: 30264329
Journal: Oncol Rep. 2018 Sep 21.
Title: MicroRNA495 regulates human gastric cancer cell apoptosis and migration through Akt and mTOR signaling.
Author: Wang, Jun|Feng, Weiwei|Dong, Yuanqiang|Mao, Xiang|Guo, Fenghua|Luo, Fen
PMID: 30272336
Journal: Int J Mol Sci. 2018 Sep 30;19(10). pii: ijms19102986.
Title: LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Author: Batool, Samana|Joseph, Thomson Patrick|Hussain, Mushraf|Vuai, Miza S|Khinsar, Kavish H|Din, Syed Riaz Ud|Padhiar, Arshad Ahmed|Zhong, Mintao|Ning, Anhong|Zhang, Wei|Cao, Jing|Huang, Min
PMID: 30274346
Journal: Onco Targets Ther. 2018 Sep 20;11:6111-6118.
Title: Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy.
Author: Li, Liangqing|Zhang, Shengwei|Xie, Diya|Chen, Hui|Zheng, Xuelan|Pan, Dun
PMID: 30275715
Journal: Mod Pathol. 2018 Oct 11. pii: 10.1038/s41379-018-0146-z.
Title: BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor.
Author: Jour, George|Vasudevaraja, Varshini|Prieto, Victor G|Snuderl, Matija|Torres-Cabala, Carlos A|Al-Rohil, Rami|Sulman, Erik P|Ballester, Leomar Y|Aung, Phyu P
PMID: 30310175
Journal: Expert Opin Drug Saf. 2018 Nov;17(11):1145-1150.
Title: The safety of apatinib for the treatment of gastric cancer.
Author: Geng, Ruixuan|Song, Li|Li, Jin|Zhao, Lin
PMID: 30324820
Journal: Cell Death Dis. 2018 Oct 19;9(11):1070.
Title: MicroRNA-495-3p inhibits multidrug resistance by modulating autophagy through GRP78/mTOR axis in gastric cancer.
Author: Chen, Sheng|Wu, Jian|Jiao, Kai|Wu, Qiong|Ma, Jiaojiao|Chen, Di|Kang, Jianqin|Zhao, Guodong|Shi, Yongquan|Fan, Daiming|Zhao, Guohong
PMID: 30341283
Journal: Int Immunopharmacol. 2018 Oct 18;65:312-322.
Title: Methionine enkephalin (MENK) inhibits human gastric cancer through regulating tumor associated macrophages (TAMs) and PI3K/AKT/mTOR signaling pathway inside cancer cells.
Author: Wang, Xiaonan|Jiao, Xue|Meng, Yiming|Chen, Hao|Griffin, Noreen|Gao, Xinghua|Shan, Fengping
PMID: 30343258
Journal: Onco Targets Ther. 2018 Oct 10;11:6705-6722.
Title: Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1alpha signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo.
Author: Chen, Min|Lu, Jian|Wei, Wei|Lv, Ying|Zhang, Xiaoqi|Yao, Yuling|Wang, Lei|Ling, Tingsheng|Zou, Xiaoping
PMID: 30349304
Journal: Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806499.
Title: Deregulation of MicroRNA-375 Inhibits Proliferation and Migration in Gastric Cancer in Association With Autophagy-Mediated AKT/mTOR Signaling Pathways.
Author: Yuan, Kai-Tao|Li, Bao-Xia|Yuan, Yu-Jie|Tan, Min|Tan, Jin-Fu|Dai, Wei-Gang|Feng, Wei-Dong|Zuo, Ji-Dong
PMID: 30355273
Journal: Cell Physiol Biochem. 2018 Oct 24;50(4):1332-1345.
Title: FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Author: Huang, Tingting|Liu, Dian|Wang, Yihua|Li, Piao|Sun, Li|Xiong, Huihua|Dai, Yuhong|Zou, Man|Yuan, Xianglin|Qiu, Hong
PMID: 30355943
Journal: Carcinogenesis. 2018 Oct 29. pii: 5146213.
Title: NUCKS1 promotes gastric cancer cell aggressiveness by upregulating IGF-1R and subsequently activating the PI3K/Akt/mTOR signaling pathway.
Author: Huang, Ya-Kai|Kang, Wei-Ming|Ma, Zhi-Qiang|Liu, Yu-Qin|Zhou, Li|Yu, Jian-Chun
PMID: 30371738
Journal: Open Biol. 2018 Oct 31;8(10). pii: rsob.180051.
Title: Signature miRNAs in peripheral blood monocytes of patients with gastric or breast cancers.
Author: Shu, Le|Wang, Zhe|Wang, Qizhi|Wang, Yumeng|Zhang, Xiaobo
PMID: 30381359