Literatures

Primary Site >> Colorectal Cancer

Gene >> MTOR

1.
Journal:	FASEB J. 2000 Nov;14(14):2329-38.
Title:	Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways.
Author:	Attoub, S\|Noe, V\|Pirola, L\|Bruyneel, E\|Chastre, E\|Mareel, M\|Wymann, M P\|Gespach, C
PMID:	11053255

2.
Journal:	Curr Med Chem. 2001 Oct;8(12):1487-503.
Title:	Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.
Author:	Owa, T\|Yoshino, H\|Yoshimatsu, K\|Nagasu, T
PMID:	11562278

3.
Journal:	J Biol Chem. 2002 Apr 19;277(16):13907-17. Epub 2002 Feb 14.
Title:	4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin.
Author:	Dilling, Michael B\|Germain, Glen S\|Dudkin, Lorina\|Jayaraman, Arun L\|Zhang, Xiongwen\|Harwood, Franklin C\|Houghton, Peter J
PMID:	11847216

4.
Journal:	J Biol Chem. 2002 Aug 2;277(31):28127-34. Epub 2002 May 8.
Title:	Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture.
Author:	Zhang, Xiongwen\|Shu, Lili\|Hosoi, Hajime\|Murti, K Gopal\|Houghton, Peter J
PMID:	12000755

5.
Journal:	Nat Genet. 2003 Dec;35(4):323-30. Epub 2003 Nov 16.
Title:	Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Author:	Aoki, Koji\|Tamai, Yoshitaka\|Horiike, Shigeo\|Oshima, Masanobu\|Taketo, Makoto M
PMID:	14625550

6.
Journal:	Cancer Res. 2004 Jan 1;64(1):229-35.
Title:	Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells.
Author:	Shao, Jinyi\|Evers, B Mark\|Sheng, Hongmiao
PMID:	14729629

7.
Journal:	Anticancer Drugs. 2005 Jun;16(5):533-41.
Title:	The patellazoles inhibit protein synthesis at nanomolar concentrations in human colon tumor cells.
Author:	Richardson, Adam D\|Aalbersberg, William\|Ireland, Chris M
PMID:	15846119

8.
Journal:	Curr Cancer Drug Targets. 2005 May;5(3):171-93.
Title:	Molecularly targeted therapy for gastrointestinal cancer.
Author:	Wiedmann, Marcus W\|Caca, Karel
PMID:	15892618

9.
Journal:	Mol Pharmacol. 2005 Aug;68(2):477-86.
Title:	Characterization of a human carcinoma cell line selected for resistance to the farnesyl transferase inhibitor 4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyri din-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxami
Author:	Bruzek, Laura M\|Poynter, Jenny N\|Kaufmann, Scott H\|Adjei, Alex A
PMID:	15901852

10.
Journal:	Cancer Res. 2005 Aug 1;65(15):6882-90.
Title:	RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.
Author:	Homicsko, Krisztian\|Lukashev, Alexander\|Iggo, Richard D
PMID:	16061672

11.
Journal:	World J Gastroenterol. 2005 Sep 7;11(33):5156-61.
Title:	Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cells.
Author:	Park, Hae-Jeong\|Yoon, Seo-Hyun\|Han, Long-Shan\|Zheng, Long-Tai\|Jung, Kyung-Hee\|Uhm, Yoon-Kyung\|Lee, Je-Hyun\|Jeong, Ji-Seon\|Joo, Woo-Sang\|Yim, Sung-Vin\|Chung, Joo-Ho\|Hong, Seon-Pyo
PMID:	16127745

12.
Journal:	Hum Gene Ther. 2005 Dec;16(12):1473-83.
Title:	Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
Author:	Lukashev, Alexander N\|Fuerer, Christophe\|Chen, Ming-Jen\|Searle, Peter\|Iggo, Richard
PMID:	16390278

13.
Journal:	J Agric Food Chem. 2006 Mar 8;54(5):1646-50.
Title:	In vitro antioxidant activity and antigenotoxicity of 5-n-alkylresorcinols.
Author:	Parikka, Kirsti\|Rowland, Ian R\|Welch, Robert W\|Wahala, Kristiina
PMID:	16506814

14.
Journal:	Cell Signal. 2006 Nov;18(11):1967-76. Epub 2006 May 3.
Title:	Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis.
Author:	Fassetta, Michela\|D'Alessandro, Lorenza\|Coltella, Nadia\|Di Renzo, Maria Flavia\|Rasola, Andrea
PMID:	16677802

15.
Journal:	Cancer Lett. 2007 Jun 18;251(1):105-13. Epub 2006 Dec 18.
Title:	Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer.
Author:	Nozawa, Hiroaki\|Watanabe, Toshiaki\|Nagawa, Hirokazu
PMID:	17175097

16.
Journal:	Virchows Arch. 2007 Mar;450(3):321-8. Epub 2007 Jan 30.
Title:	Co-expression of EGF receptor, TGFalpha and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosis.
Author:	Tampellini, Marco\|Longo, Marina\|Cappia, Susanna\|Bacillo, Elisa\|Alabiso, Irene\|Volante, Marco\|Dogliotti, Luigi\|Papotti, Mauro
PMID:	17265080

17.
Journal:	Autophagy. 2007 Sep-Oct;3(5):468-71. Epub 2007 Apr 23.
Title:	Signal-dependent control of autophagy and cell death in colorectal cancer cell: the role of the p38 pathway.
Author:	Simone, Cristiano
PMID:	17495519

18.
Journal:	Cancer Res. 2007 Aug 1;67(15):7106-12.
Title:	Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
Author:	Ma, Li\|Teruya-Feldstein, Julie\|Bonner, Pauline\|Bernardi, Rosa\|Franz, David Neal\|Witte, David\|Cordon-Cardo, Carlos\|Pandolfi, Pier Paolo
PMID:	17671177

19.
Journal:	World J Gastroenterol. 2007 Nov 28;13(44):5845-56.
Title:	Exploiting novel molecular targets in gastrointestinal cancers.
Author:	Ma, Wen W\|Hidalgo, Manuel
PMID:	17990350

20.
Journal:	Zhonghua Zhong Liu Za Zhi. 2007 Dec;29(12):889-93.
Title:	[Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells].
Author:	Zhang, Yan-Jie\|Fang, Jing-Yuan\|Sun, Dan-Feng\|Zhao, Shu-Liang\|Shen, Guan-Feng\|Zheng, Qing\|Zhu, Hong-Yin
PMID:	18478925

21.
Journal:	Oncogene. 2008 Feb 14;27(8):1055-62. Epub 2007 Aug 13.
Title:	Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.
Author:	Gadir, N\|Jackson, D N\|Lee, E\|Foster, D A
PMID:	17700525

22.
Journal:	Cell Signal. 2008 Jan;20(1):219-29. Epub 2007 Oct 14.
Title:	Both Wnt and mTOR signaling pathways are involved in insulin-stimulated proto-oncogene expression in intestinal cells.
Author:	Sun, Jane\|Jin, Tianru
PMID:	17993259

23.
Journal:	Clin Cancer Res. 2008 Feb 1;14(3):892-900.
Title:	Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.
Author:	Manegold, Philipp C\|Paringer, Carmen\|Kulka, Ulrike\|Krimmel, Klaus\|Eichhorn, Martin E\|Wilkowski, Ralf\|Jauch, Karl-Walter\|Guba, Markus\|Bruns, Christiane J
PMID:	18245553

24.
Journal:	Pflugers Arch. 2008 Aug;456(5):847-55.
Title:	Upregulation of colonic ion channels in APC ( Min/+ ) mice.
Author:	Ousingsawat, Jiraporn\|Spitzner, Melanie\|Schreiber, Rainer\|Kunzelmann, Karl
PMID:	18247045

25.
Journal:	Br J Cancer. 2008 Mar 11;98(5):923-30.
Title:	Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs.
Author:	Bianco, R\|Garofalo, S\|Rosa, R\|Damiano, V\|Gelardi, T\|Daniele, G\|Marciano, R\|Ciardiello, F\|Tortora, G
PMID:	18319715

26.
Journal:	J Clin Oncol. 2008 Apr 1;26(10):1603-10.
Title:	Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
Author:	Tabernero, Josep\|Rojo, Federico\|Calvo, Emiliano\|Burris, Howard\|Judson, Ian\|Hazell, Katharine\|Martinelli, Erika\|Ramon y Cajal, Santiago\|Jones, Suzanne\|Vidal, Laura\|Shand, Nicholas\|Macarulla, Teresa\|Ramos, Francisco Javier\|Dimitrijevic, Sasa\|Zoellner, Ulrik
PMID:	18332469

27.
Journal:	Virchows Arch. 2008 May;452(5):535-44.
Title:	Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Author:	Greijer, Astrid E\|Delis-van Diemen, Pien M\|Fijneman, Remond J A\|Giles, Rachel H\|Voest, Emile E\|van Hinsbergh, Victor W M\|Meijer, Gerrit A
PMID:	18351386

28.
Journal:	Cancer Res. 2008 Apr 1;68(7):2384-90.
Title:	Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Author:	Zeng, Xuehuo\|Kinsella, Timothy J
PMID:	18381446

29.
Journal:	Int J Cancer. 2008 Aug 1;123(3):687-94.
Title:	Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.
Author:	Protiva, Petr\|Hopkins, Michael E\|Baggett, Scott\|Yang, Hui\|Lipkin, Martin\|Holt, Peter R\|Kennelly, Edward J\|Bernard, Weinstein I
PMID:	18470880

30.
Journal:	Curr Opin Oncol. 2008 Jul;20(4):454-8.
Title:	Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer?
Author:	Laurent-Puig, Pierre\|Taieb, Julien
PMID:	18525343

31.
Journal:	Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13544-9.
Title:	Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice.
Author:	Fujishita, Teruaki\|Aoki, Koji\|Lane, Heidi A\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	18768809

32.
Journal:	Cancer Res. 2008 Sep 15;68(18):7270-7.
Title:	LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Author:	Zhong, Diansheng\|Liu, Xiuju\|Khuri, Fadlo R\|Sun, Shi-Yong\|Vertino, Paula M\|Zhou, Wei
PMID:	18794113

33.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1237-45.
Title:	A novel mTOR inhibitor is efficacious in a murine model of colitis.
Author:	Bhonde, Mandar R\|Gupte, Ravindra D\|Dadarkar, Shruta D\|Jadhav, Mahesh G\|Tannu, Aditi A\|Bhatt, Pooja\|Bhatia, Dimple R\|Desai, Nikesh K\|Deore, Vijaykumar\|Yewalkar, Nilambari\|Vishwakarma, Ram A\|Sharma, Somesh\|Kumar, Sanjay\|Dagia, Nilesh M
PMID:	18927209

34.
Journal:	Gastrointest Cancer Res. 2008 Jul;2(4 Suppl):S20-2.
Title:	Colorectal Cancer Treatment: What's Next? (or: Is There Life After EGFR and VEGF?).
Author:	Saltz, Leonard
PMID:	19343143

35.
Journal:	J Nutr Biochem. 2009 Jun;20(6):426-34.
Title:	Concomitant supplementation of lycopene and eicosapentaenoic acid inhibits the proliferation of human colon cancer cells.
Author:	Tang, Feng-Yao\|Cho, Hsin-Ju\|Pai, Man-Hui\|Chen, Ye-Hsin
PMID:	18708285

36.
Journal:	Int J Oncol. 2009 Feb;34(2):339-44.
Title:	Adiponectin inhibits colorectal cancer cell growth through the AMPK/mTOR pathway.
Author:	Sugiyama, Michiko\|Takahashi, Hirokazu\|Hosono, Kunihiro\|Endo, Hiroki\|Kato, Shingo\|Yoneda, Kyoko\|Nozaki, Yuichi\|Fujita, Koji\|Yoneda, Masato\|Wada, Koichiro\|Nakagama, Hitoshi\|Nakajima, Atsushi
PMID:	19148467

37.
Journal:	Cancer Invest. 2009 Mar;27(3):273-85.
Title:	Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer.
Author:	Zhang, Yan-Jie\|Tian, Xiao-Qing\|Sun, Dan-Feng\|Zhao, Shu-Liang\|Xiong, Hua\|Fang, Jing-Yuan
PMID:	19194827

38.
Journal:	Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2835-40.
Title:	Knockin of mutant PIK3CA activates multiple oncogenic pathways.
Author:	Gustin, John P\|Karakas, Bedri\|Weiss, Michele B\|Abukhdeir, Abde M\|Lauring, Josh\|Garay, Joseph P\|Cosgrove, David\|Tamaki, Akina\|Konishi, Hiroyuki\|Konishi, Yuko\|Mohseni, Morassa\|Wang, Grace\|Rosen, D Marc\|Denmeade, Samuel R\|Higgins, Michaela J\|Vitolo, Michele
PMID:	19196980

39.
Journal:	Int J Colorectal Dis. 2009 Jun;24(6):629-39.
Title:	Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.
Author:	Zhang, Yan-Jie\|Zhao, Shu-Liang\|Tian, Xiao-Qing\|Sun, Dan-Feng\|Xiong, Hua\|Dai, Qiang\|Li, Xiao-Qiang\|Fang, Jing-Yuan
PMID:	19229543

40.
Journal:	Cancer Biol Ther. 2009 Aug;8(15):1463-9. Epub 2009 Aug 8.
Title:	Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues.
Author:	Fan, Songqing\|Ramalingam, Suresh S\|Kauh, John\|Xu, Zhiheng\|Khuri, Fadlo R\|Sun, Shi-Yong
PMID:	19483468

41.
Journal:	Ann Surg Oncol. 2009 Sep;16(9):2617-28.
Title:	mTOR signaling pathway is a target for the treatment of colorectal cancer.
Author:	Zhang, Yan-Jie\|Dai, Qiang\|Sun, Dan-Feng\|Xiong, Hua\|Tian, Xiao-Qing\|Gao, Feng-Hou\|Xu, Mang-Hua\|Chen, Guo-Qiang\|Han, Ze-Guang\|Fang, Jing-Yuan
PMID:	19517193

42.
Journal:	Curr Treat Options Oncol. 2009 Apr;10(1-2):126-40.
Title:	Ewing's sarcoma: standard and experimental treatment options.
Author:	Subbiah, Vivek\|Anderson, Pete\|Lazar, Alexander J\|Burdett, Emily\|Raymond, Kevin\|Ludwig, Joseph A
PMID:	19533369

43.
Journal:	Biochem Biophys Res Commun. 2009 Sep 4;386(4):598-601.
Title:	Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells.
Author:	Wu, William Ka Kei\|Volta, Viviana\|Cho, Chi Hin\|Wu, Ya Chun\|Li, Hai Tao\|Yu, Le\|Li, Zhi Jie\|Sung, Joseph Jao Yiu
PMID:	19540199

44.
Journal:	Ann Surg Oncol. 2009 Sep;16(9):2629-37.
Title:	Rapamycin inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell proliferation.
Author:	Rupertus, Kathrin\|Dahlem, Christian\|Menger, Michael D\|Schilling, Martin K\|Kollmar, Otto
PMID:	19551445

45.
Journal:	J Gastrointest Surg. 2009 Oct;13(10):1781-90.
Title:	Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1.
Author:	Wagner, Markus\|Roh, Vincent\|Strehlen, Michael\|Laemmle, Alexander\|Stroka, Deborah\|Egger, Bernhard\|Trochsler, Markus\|Hunt, Kelly K\|Candinas, Daniel\|Vorburger, Stephan A
PMID:	19565301

46.
Journal:	Int J Cancer. 2009 Nov 15;125(10):2332-41.
Title:	Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.
Author:	Balmanno, Kathryn\|Chell, Simon D\|Gillings, Annette S\|Hayat, Shaista\|Cook, Simon J
PMID:	19637312

47.
Journal:	Anticancer Res. 2009 Aug;29(8):3185-90.
Title:	Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.
Author:	Johnson, Sara M\|Gulhati, Pat\|Arrieta, Isela\|Wang, Xiaofu\|Uchida, Tatsuo\|Gao, Tianyan\|Evers, B Mark
PMID:	19661333

48.
Journal:	Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title:	Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author:	Meriggi, F\|Di Biasi, B\|Abeni, C\|Zaniboni, A
PMID:	19663767

49.
Journal:	Cell Cycle. 2009 Nov 15;8(22):3684-7.
Title:	The role of mTORC1 pathway in intestinal tumorigenesis.
Author:	Fujishita, Teruaki\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	19855161

50.
Journal:	J Agric Food Chem. 2009 Dec 9;57(23):11154-60.
Title:	Antioxidant and biological properties of bioactive phenolic compounds from Quercus suber L.
Author:	Fernandes, Ana\|Fernandes, Iva\|Cruz, Luis\|Mateus, Nuno\|Cabral, Miguel\|de Freitas, Victor
PMID:	19888728

51.
Journal:	Mol Cancer. 2009 Nov 12;8:100.
Title:	A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Author:	Nakamura, Yoshitaka\|Yogosawa, Shingo\|Izutani, Yasuyuki\|Watanabe, Hirotsuna\|Otsuji, Eigo\|Sakai, Tosiyuki
PMID:	19909554

52.
Journal:	Clin Cancer Res. 2009 Dec 1;15(23):7207-16.
Title:	Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.
Author:	Gulhati, Pat\|Cai, Qingsong\|Li, Jing\|Liu, Jianyu\|Rychahou, Piotr G\|Qiu, Suimin\|Lee, Eun Y\|Silva, Scott R\|Bowen, Kanika A\|Gao, Tianyan\|Evers, B Mark
PMID:	19934294

53.
Journal:	Oncology. 2009;77 Suppl 1:69-74.
Title:	The dark side of the moon: the PI3K/PTEN/AKT pathway in colorectal carcinoma.
Author:	Silvestris, Nicola\|Tommasi, Stefania\|Petriella, Daniela\|Santini, Daniele\|Fistola, Ettore\|Russo, Antonio\|Numico, Gianmauro\|Tonini, Giuseppe\|Maiello, Evaristo\|Colucci, Giuseppe
PMID:	20130434

54.
Journal:	Cancer Lett. 2010 Feb 1;288(1):68-74.
Title:	Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell.
Author:	Xiong, Hai-yan\|Guo, Xian-ling\|Bu, Xin-xin\|Zhang, Shan-shan\|Ma, Nan-nan\|Song, Jian-rui\|Hu, Fei\|Tao, Shuang-fen\|Sun, Kai\|Li, Rong\|Wu, Meng-chao\|Wei, Li-xin
PMID:	19660860

55.
Journal:	Fam Cancer. 2010 Jun;9(2):125-9.
Title:	Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.
Author:	Ekstrand, Anna Isinger\|Jonsson, Mats\|Lindblom, Annika\|Borg, Ake\|Nilbert, Mef
PMID:	19731079

56.
Journal:	J Cell Mol Med. 2010 Jun;14(6B):1520-31.
Title:	Translational up-regulation of Aurora-A in EGFR-overexpressed cancer.
Author:	Lai, Chien-Hsien\|Tseng, Joseph T\|Lee, Yi-Chao\|Chen, Ying-Ju\|Lee, Jeng-Chang\|Lin, Bo-Wen\|Huang, Tai-Chien\|Liu, Yao-Wen\|Leu, Tzeng-Horng\|Liu, Yi-Wen\|Chen, Ya-Ping\|Chang, Wen-Chang\|Hung, Liang-Yi
PMID:	19799648

57.
Journal:	Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1565-70.
Title:	Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Author:	Hung, Kenneth E\|Maricevich, Marco A\|Richard, Larissa Georgeon\|Chen, Wei Y\|Richardson, Michael P\|Kunin, Alexandra\|Bronson, Roderick T\|Mahmood, Umar\|Kucherlapati, Raju
PMID:	20080688

58.
Journal:	Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2598-603.
Title:	Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Author:	Ericson, Kajsa\|Gan, Christine\|Cheong, Ian\|Rago, Carlo\|Samuels, Yardena\|Velculescu, Victor E\|Kinzler, Kenneth W\|Huso, David L\|Vogelstein, Bert\|Papadopoulos, Nickolas
PMID:	20133737

59.
Journal:	Carcinogenesis. 2010 Jun;31(6):1092-9.
Title:	Suppression of mTOR via Akt-dependent and -independent mechanisms in selenium-treated colon cancer cells: involvement of AMPKalpha1.
Author:	Lee, Yun-Kyoung\|Park, Song Yi\|Kim, Young-Min\|Kim, Dong Chool\|Lee, Won Sup\|Surh, Young-Joon\|Park, Ock Jin
PMID:	20164123

60.
Journal:	Mol Cancer. 2010 Mar 12;9:57.
Title:	Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo.
Author:	Roulin, Didier\|Cerantola, Yannick\|Dormond-Meuwly, Anne\|Demartines, Nicolas\|Dormond, Olivier
PMID:	20226010

61.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77.
Title:	Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B.
Author:	Rafiee, Parvaneh\|Binion, David G\|Wellner, Michael\|Behmaram, Behnaz\|Floer, Martin\|Mitton, Elizabeth\|Nie, Linghui\|Zhang, Zhihong\|Otterson, Mary F
PMID:	20299603

62.
Journal:	Anticancer Res. 2010 Mar;30(3):785-92.
Title:	Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
Author:	Gao, Xiaohua\|Deeb, Dorrah\|Hao, Jiang\|Liu, Yongbo\|Arbab, Ali S\|Dulchavsky, Scott A\|Gautam, Subhash C
PMID:	20392997

63.
Journal:	Anticancer Res. 2010 Mar;30(3):799-804.
Title:	Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin.
Author:	Abdelnour-Berchtold, Etienne\|Cerantola, Yannick\|Roulin, Didier\|Dormond-Meuwly, Anne\|Demartines, Nicolas\|Dormond, Olivier
PMID:	20392999

64.
Journal:	Curr Clin Pharmacol. 2010 Aug;5(3):166-77.
Title:	Molecular targeted therapy in prevalent tumors: learning from the past and future perspectives.
Author:	Metzger-Filho, Otto\|Moulin, Camilo\|Awada, Ahmad
PMID:	20406173

65.
Journal:	Cancer Res. 2010 May 1;70(9):3677-86.
Title:	Molecular target class is predictive of in vitro response profile.
Author:	Greshock, Joel\|Bachman, Kurtis E\|Degenhardt, Yan Y\|Jing, Junping\|Wen, Yuan H\|Eastman, Stephen\|McNeil, Elizabeth\|Moy, Christopher\|Wegrzyn, Ronald\|Auger, Kurt\|Hardwicke, Mary Ann\|Wooster, Richard
PMID:	20406975

66.
Journal:	Gastroenterology. 2010 Aug;139(2):574-85.
Title:	Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Author:	Xiao, Hui\|Yin, Weiguo\|Khan, Mohammed A\|Gulen, Muhammet F\|Zhou, Hang\|Sham, Ho Pan\|Jacobson, Kevan\|Vallance, Bruce A\|Li, Xiaoxia
PMID:	20416302

67.
Journal:	J Am Coll Surg. 2010 May;210(5):767-76, 776-8.
Title:	Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.
Author:	Johnson, Sara M\|Gulhati, Pat\|Rampy, Bill A\|Han, Yimei\|Rychahou, Piotr G\|Doan, Hung Q\|Weiss, Heidi L\|Evers, B Mark
PMID:	20421047

68.
Journal:	J Biol Chem. 2010 Aug 6;285(32):24987-98.
Title:	Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1.
Author:	Larson, Yan\|Liu, Jianyu\|Stevens, Payton D\|Li, Xin\|Li, Jing\|Evers, B Mark\|Gao, Tianyan
PMID:	20530489

69.
Journal:	Cancer Res. 2010 Jul 1;70(13):5507-17.
Title:	The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.
Author:	Al-Saffar, Nada M S\|Jackson, L Elizabeth\|Raynaud, Florence I\|Clarke, Paul A\|Ramirez de Molina, Ana\|Lacal, Juan C\|Workman, Paul\|Leach, Martin O
PMID:	20551061

70.
Journal:	Carcinogenesis. 2010 Sep;31(9):1604-11.
Title:	Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Lundgreen, Abbie\|Fitzpatrick, Francis A\|Curtin, Karen\|Wolff, Roger K
PMID:	20622004

71.
Journal:	Nat Cell Biol. 2010 Aug;12(8):781-90.
Title:	Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation.
Author:	Gao, Chan\|Cao, Weipeng\|Bao, Lan\|Zuo, Wei\|Xie, Guoming\|Cai, Tiantian\|Fu, Wei\|Zhang, Jian\|Wu, Wei\|Zhang, Xu\|Chen, Ye-Guang
PMID:	20639871

72.
Journal:	Cancer Res. 2010 Aug 15;70(16):6629-38.
Title:	Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Author:	Metcalfe, Ciara\|Ibrahim, Ashraf E K\|Graeb, Michael\|de la Roche, Marc\|Schwarz-Romond, Thomas\|Fiedler, Marc\|Winton, Douglas J\|Corfield, Anthony\|Bienz, Mariann
PMID:	20663899

73.
Journal:	Int J Mol Med. 2010 Sep;26(3):341-9.
Title:	Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells.
Author:	Auyeung, Kathy Ka-Wai\|Mok, Nga-Lai\|Wong, Ching-Man\|Cho, Chi-Hin\|Ko, Joshua Ka-Shun
PMID:	20664949

74.
Journal:	Cell Cycle. 2010 Jul 15;9(14):2803-13. Epub 2010 Jul 3.
Title:	FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways.
Author:	Rodriguez-Jimenez, Francisco Javier\|Moreno-Manzano, Victoria\|Mateos-Gregorio, Pablo\|Royo, Inmaculada\|Erceg, Slaven\|Murguia, Jose Ramon\|Sanchez-Puelles, Jose Maria
PMID:	20676050

75.
Journal:	Dev Cell. 2010 Aug 17;19(2):259-69.
Title:	Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Author:	Ashton, Gabrielle H\|Morton, Jennifer P\|Myant, Kevin\|Phesse, Toby J\|Ridgway, Rachel A\|Marsh, Victoria\|Wilkins, Julie A\|Athineos, Dimitris\|Muncan, Vanesa\|Kemp, Richard\|Neufeld, Kristi\|Clevers, Hans\|Brunton, Valerie\|Winton, Douglas J\|Wang, Xiaoyan\|Sears, Ros
PMID:	20708588

76.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1025-33.
Title:	Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.
Author:	Baba, Y\|Nosho, K\|Shima, K\|Meyerhardt, J A\|Chan, A T\|Engelman, J A\|Cantley, L C\|Loda, M\|Giovannucci, E\|Fuchs, C S\|Ogino, S
PMID:	20808308

77.
Journal:	Mol Cancer Ther. 2010 Dec;9(12):3158-63.
Title:	Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis.
Author:	Dumstorf, Chad A\|Konicek, Bruce W\|McNulty, Ann M\|Parsons, Stephen H\|Furic, Luc\|Sonenberg, Nahum\|Graff, Jeremy R
PMID:	20971826

78.
Journal:	Oncol Rep. 2010 Dec;24(6):1471-7.
Title:	Anthocyanins are novel AMPKalpha1 stimulators that suppress tumor growth by inhibiting mTOR phosphorylation.
Author:	Lee, Yun-Kyoung\|Lee, Won Sup\|Kim, Gon Sup\|Park, Ock Jin
PMID:	21042741

79.
Journal:	Nutr Res Pract. 2010 Oct;4(5):351-5.
Title:	Significance of p27 as potential biomarker for intracellular oxidative status.
Author:	Quintos, Lesley\|Lee, In Ae\|Kim, Hyo Jung\|Lim, Ji-Sun\|Park, Jia\|Sung, Mi-Kyung\|Seo, Young Rok\|Kim, Jong-Sang
PMID:	21103079

80.
Journal:	Oncology. 2010;79(3-4):278-82.
Title:	Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Author:	Kim, Jong Gwang\|Chae, Yee Soo\|Sohn, Sang Kyun\|Kang, Byung Woog\|Moon, Joon Ho\|Lee, Soo Jung\|Jeon, Seong Woo\|Park, Jun Seok\|Park, Jin Young\|Choi, Gyu Seog
PMID:	21412012

81.
Journal:	Ann Surg Oncol. 2011 Feb;18(2):580-8.
Title:	mTOR signaling is involved in indomethacin and nimesulide suppression of colorectal cancer cell growth via a COX-2 independent pathway.
Author:	Zhang, Yan-Jie\|Bao, Yu-Jie\|Dai, Qiang\|Yang, Wen-Yan\|Cheng, Peng\|Zhu, Li-Ming\|Wang, Bi-Jun\|Jiang, Fo-Hu
PMID:	20803081

82.
Journal:	J Cell Physiol. 2011 Apr;226(4):1060-8.
Title:	Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1alpha translational pathway in colorectal cancer cells.
Author:	Chang, Li-Hsun\|Chen, Chun-Han\|Huang, Der-Yi\|Pai, Hui-Chen\|Pan, Shiow-Lin\|Teng, Che-Ming
PMID:	20857420

83.
Journal:	Anticancer Drugs. 2011 Jan;22(1):58-78.
Title:	Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.
Author:	O'Reilly, Terry\|McSheehy, Paul M J\|Wartmann, Markus\|Lassota, Peter\|Brandt, Ralf\|Lane, Heidi A
PMID:	20890178

84.
Journal:	Cell Death Differ. 2011 Apr;18(4):602-18.
Title:	Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.
Author:	Tang, Y\|Chen, Y\|Jiang, H\|Nie, D
PMID:	20930850

85.
Journal:	Oncogene. 2011 Feb 3;30(5):561-74.
Title:	Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab.
Author:	Dunn, E F\|Iida, M\|Myers, R A\|Campbell, D A\|Hintz, K A\|Armstrong, E A\|Li, C\|Wheeler, D L
PMID:	20956938

86.
Journal:	Mutat Res. 2011 Jan 10;706(1-2):13-20.
Title:	Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Wolff, Roger K
PMID:	21035469

87.
Journal:	Phytother Res. 2011 Jun;25(6):833-7.
Title:	Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.
Author:	Lee, Myung Sun\|Cha, Eun Young\|Sul, Ji Young\|Song, In Sang\|Kim, Ji Yeon
PMID:	21089180

88.
Journal:	Autophagy. 2011 Feb;7(2):235-7. Epub 2011 Feb 1.
Title:	The role of short-chain fatty acids in orchestrating two types of programmed cell death in colon cancer.
Author:	Tang, Yong\|Chen, Yakun\|Jiang, Hongmei\|Nie, Daotai
PMID:	21160278

89.
Journal:	J Biol Chem. 2011 Feb 25;286(8):6510-20.
Title:	mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
Author:	Liu, Jianyu\|Stevens, Payton D\|Gao, Tianyan
PMID:	21177869

90.
Journal:	Mol Cancer Ther. 2011 Mar;10(3):558-65.
Title:	PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors.
Author:	Janku, Filip\|Tsimberidou, Apostolia M\|Garrido-Laguna, Ignacio\|Wang, Xuemei\|Luthra, Rajyalakshmi\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Moroney, John W\|Piha-Paul, Sarina A\|Wheler, Jennifer J\|Moulder, Stacy L\|Fu, Siqing\|Kurzrock, Razelle
PMID:	21216929

91.
Journal:	Cancer Res. 2011 Mar 1;71(5):1849-57.
Title:	Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
Author:	Konicek, Bruce W\|Stephens, Jennifer R\|McNulty, Ann M\|Robichaud, Nathaniel\|Peery, Robert B\|Dumstorf, Chad A\|Dowless, Michele S\|Iversen, Philip W\|Parsons, Stephen\|Ellis, Karen E\|McCann, Denis J\|Pelletier, Jerry\|Furic, Luc\|Yingling, Jonathan M\|Stancato, Loui
PMID:	21233335

92.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title:	Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author:	Liu, Xin\|Guo, Wei-Jian\|Zhang, Xiao-Wei\|Cai, Xu\|Tian, Shu\|Li, Jin
PMID:	21286718

93.
Journal:	Cancer Sci. 2011 May;102(5):999-1006.
Title:	Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells.
Author:	Habeeb, Baker S\|Kitayama, Joji\|Nagawa, Hirokazu
PMID:	21299716

94.
Journal:	Cancer Res. 2011 May 1;71(9):3246-56.
Title:	mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Author:	Gulhati, Pat\|Bowen, Kanika A\|Liu, Jianyu\|Stevens, Payton D\|Rychahou, Piotr G\|Chen, Min\|Lee, Eun Y\|Weiss, Heidi L\|O'Connor, Kathleen L\|Gao, Tianyan\|Evers, B Mark
PMID:	21430067

95.
Journal:	J Agric Food Chem. 2011 May 25;59(10):5357-63.
Title:	Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin.
Author:	Chang, Hsiang-Yu\|Kao, Ming-Ching\|Way, Tzong-Der\|Ho, Chi-Tang\|Fu, Earl
PMID:	21504235

96.
Journal:	Cancer Res. 2011 Jun 15;71(12):4172-82.
Title:	Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations.
Author:	Osada, Takuya\|Chen, Minyong\|Yang, Xiao Yi\|Spasojevic, Ivan\|Vandeusen, Jeffrey B\|Hsu, David\|Clary, Bryan M\|Clay, Timothy M\|Chen, Wei\|Morse, Michael A\|Lyerly, H Kim
PMID:	21531761

97.
Journal:	J Med Food. 2011 Oct;14(10):1107-17.
Title:	Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
Author:	Turktekin, Mehmet\|Konac, Ece\|Onen, H Ilke\|Alp, Ebru\|Yilmaz, Akin\|Menevse, Sevda
PMID:	21548803

98.
Journal:	Chem Biol Interact. 2011 Aug 15;193(1):43-9.
Title:	Antitumor effects of a novel benzonaphthofurandione derivative (8e) on the human colon cancer cells in vitro and in vivo through cell cycle arrest accompanied with the modulation of EGFR and mTOR signaling.
Author:	Chung, Hwa-Jin\|Rhee, Hee-Kyung\|Lee, Sang Kook\|Park Choo, Hea-Young
PMID:	21600193

99.
Journal:	Mol Cell Proteomics. 2011 Oct;10(10):M110.005397.
Title:	Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells.
Author:	Lei, Yunlong\|Huang, Kai\|Gao, Cong\|Lau, Quek Choon\|Pan, Hua\|Xie, Ke\|Li, Jingyi\|Liu, Rui\|Zhang, Tao\|Xie, Na\|Nai, Huey Shan\|Wu, Hong\|Dong, Qiang\|Zhao, Xia\|Nice, Edouard C\|Huang, Canhua\|Wei, Yuquan
PMID:	21622897

100.
Journal:	Mol Cancer Ther. 2011 Aug;10(8):1394-406.
Title:	Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin.
Author:	Bhagwat, Shripad V\|Gokhale, Prafulla C\|Crew, Andrew P\|Cooke, Andy\|Yao, Yan\|Mantis, Christine\|Kahler, Jennifer\|Workman, Jennifer\|Bittner, Mark\|Dudkin, Lorina\|Epstein, David M\|Gibson, Neil W\|Wild, Robert\|Arnold, Lee D\|Houghton, Peter J\|Pachter, Jonathan A
PMID:	21673091

101.
Journal:	J Exp Ther Oncol. 2011;9(2):119-27.
Title:	Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.
Author:	Gao, Xiaohua\|Deeb, Dorrah\|Liu, Patricia\|Liu, Yongbo\|Arbab-Ali, Syed\|Dulchavsky, Scott A\|Gautam, Subhash C
PMID:	21699019

102.
Journal:	Radiother Oncol. 2011 Jun;99(3):293-9.
Title:	AMPK regulates metabolism and survival in response to ionizing radiation.
Author:	Zannella, Vanessa E\|Cojocari, Dan\|Hilgendorf, Susan\|Vellanki, Ravi N\|Chung, Stephen\|Wouters, Bradly G\|Koritzinsky, Marianne
PMID:	21715037

103.
Journal:	Biochem Biophys Res Commun. 2011 Aug 12;411(4):751-6.
Title:	Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
Author:	Yu, Zhiwei\|Cui, Binbin\|Jin, Yinghu\|Chen, Haipeng\|Wang, Xishan
PMID:	21782788

104.
Journal:	J Surg Res. 2011 Oct;170(2):e197-209.
Title:	The cytostatic effects of lovastatin on ACC-MESO-1 cells.
Author:	Asakura, Keisuke\|Izumi, Yotaro\|Yamamoto, Michiko\|Yamauchi, Yoshikane\|Kawai, Kenji\|Serizawa, Akihiko\|Mizushima, Tomoko\|Ohmura, Mitsuyo\|Kawamura, Masafumi\|Wakui, Masatoshi\|Adachi, Takeshi\|Nakamura, Masato\|Suematsu, Makoto\|Nomori, Hiroaki
PMID:	21816418

105.
Journal:	PLoS One. 2011;6(7):e22769.
Title:	PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.
Author:	Janku, Filip\|Lee, J Jack\|Tsimberidou, Apostolia M\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Fu, Siqing\|Luthra, Rajyalakshmi\|Garrido-Laguna, Ignacio\|Kurzrock, Razelle
PMID:	21829508

106.
Journal:	Cancer Prev Res (Phila). 2011 Nov;4(11):1842-51.
Title:	(3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo.
Author:	Kim, Dong Joon\|Reddy, Kanamata\|Kim, Myoung Ok\|Li, Yan\|Nadas, Janos\|Cho, Yong-Yeon\|Kim, Jong-Eun\|Shim, Jung-Hyun\|Song, Nu Ry\|Carper, Andria\|Lubet, Ronald A\|Bode, Ann M\|Dong, Zigang
PMID:	21885813

107.
Journal:	Nat Med. 2011 Sep 25;17(10):1298-303.
Title:	Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.
Author:	Diouf, Barthelemy\|Cheng, Qing\|Krynetskaia, Natalia F\|Yang, Wenjian\|Cheok, Meyling\|Pei, Deqing\|Fan, Yiping\|Cheng, Cheng\|Krynetskiy, Evgeny Y\|Geng, Hui\|Chen, Siying\|Thierfelder, William E\|Mullighan, Charles G\|Downing, James R\|Hsieh, Peggy\|Pui, Ching-Hon\|Rel
PMID:	21946537

108.
Journal:	PLoS One. 2011;6(9):e24650.
Title:	The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.
Author:	White, James P\|Baynes, John W\|Welle, Stephen L\|Kostek, Matthew C\|Matesic, Lydia E\|Sato, Shuichi\|Carson, James A
PMID:	21949739

109.
Journal:	Biol Pharm Bull. 2011;34(10):1553-8.
Title:	Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells.
Author:	Khanal, Prem\|Kang, Bong Seok\|Yun, Hyo Jeong\|Cho, Hae-Guk\|Makarieva, Tatyana Nikolaevna\|Choi, Hong Seok
PMID:	21963494

110.
Journal:	PLoS One. 2011;6(9):e25132.
Title:	The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.
Author:	Roper, Jatin\|Richardson, Michael P\|Wang, Wei Vivian\|Richard, Larissa Georgeon\|Chen, Wei\|Coffee, Erin M\|Sinnamon, Mark J\|Lee, Lydia\|Chen, Peng-Chieh\|Bronson, Roderick T\|Martin, Eric S\|Hung, Kenneth E
PMID:	21966435

111.
Journal:	Nutr Cancer. 2011 Nov;63(8):1226-34.
Title:	Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21999454

112.
Journal:	Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1197-202.
Title:	Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro.
Author:	Bijnsdorp, I V\|Peters, G J
PMID:	22132975

113.
Journal:	Asian Pac J Cancer Prev. 2011;12(10):2581-4.
Title:	Clinical significance of mTOR and p-mTOR protein expression in human colorectal carcinomas.
Author:	Wang, Di\|Chen, Jian\|Guo, Fengjie\|Chen, Hui\|Duan, Zhi\|Wei, Mei-Yan\|Xu, Qi-Mei\|Wang, Liang-Hua\|Zhong, Mei-Zuo
PMID:	22320958

114.
Journal:	Zhonghua Yi Xue Za Zhi. 2011 Sep 27;91(36):2564-7.
Title:	[RAD001 reverses radio-resistance and exerts synergistic tumor inhibition with 5-fluorouracil].
Author:	Xin, Ying\|Cong, Wei\|Zhou, Ning\|Hong, De-Fei\|Cai, Xiu-Jun
PMID:	22321888

115.
Journal:	Zhonghua Yi Xue Za Zhi. 2011 Nov 8;91(41):2899-902.
Title:	[Expression of mammalian target of rapamycin in colon cancer and its effect on proliferation and apoptosis of human colon cancer HT-29 cells].
Author:	Zhang, Zhi-yong\|Zhang, Xie-fu
PMID:	22333609

116.
Journal:	Eur J Cancer. 2012 Feb;48(3):396-406.
Title:	The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Author:	Hernlund, Emma\|Olofsson, Maria Hagg\|Fayad, Walid\|Fryknas, Marten\|Lesiak-Mieczkowska, Karolina\|Zhang, Xiaonan\|Brnjic, Slavica\|Schmidt, Vivien\|D'Arcy, Padraig\|Sjoblom, Tobias\|De Milito, Angelo\|Larsson, Rolf\|Linder, Stig
PMID:	22154651

117.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title:	Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author:	Vermaat, Joost S\|Nijman, Isaac J\|Koudijs, Marco J\|Gerritse, Frank L\|Scherer, Stefan J\|Mokry, Michal\|Roessingh, Wijnand M\|Lansu, Nico\|de Bruijn, Ewart\|van Hillegersberg, Richard\|van Diest, Paul J\|Cuppen, Edwin\|Voest, Emile E
PMID:	22173549

118.
Journal:	Gut. 2012 Dec;61(12):1708-15.
Title:	5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.
Author:	Baan, Bart\|Dihal, Ashwin A\|Hoff, Eva\|Bos, Carina L\|Voorneveld, Philip W\|Koelink, Pim J\|Wildenberg, Manon E\|Muncan, Vanesa\|Heijmans, Jarom\|Verspaget, Hein W\|Richel, Dick J\|Hardwick, James C H\|Hommes, Daniel W\|Peppelenbosch, Maikel P\|van den Brink, Gijs R
PMID:	22187071

119.
Journal:	Toxicol In Vitro. 2012 Mar;26(2):258-68.
Title:	Selenite-induced apoptosis and autophagy in colon cancer cells.
Author:	Kralova, Vera\|Benesova, Sona\|Cervinka, Miroslav\|Rudolf, Emil
PMID:	22200533

120.
Journal:	J Cell Biochem. 2012 May;113(5):1733-43.
Title:	Silibinin suppresses the maintenance of colorectal cancer stem-like cells by inhibiting PP2A/AKT/mTOR pathways.
Author:	Wang, Jir-You\|Chang, Chia-Chi\|Chiang, Chao-Ching\|Chen, Wei-Ming\|Hung, Shih-Chieh
PMID:	22213051

121.
Journal:	J Nutr Biochem. 2012 Oct;23(10):1302-13.
Title:	Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model.
Author:	Tang, Feng-Yao\|Pai, Man-Hui\|Chiang, En-Pei Isabel
PMID:	22221675

122.
Journal:	Transplantation. 2012 Mar 15;93(5):509-17.
Title:	Role of oncogenic pathways and KRAS/BRAF mutations in the behavior of colon adenocarcinoma in renal transplant patients.
Author:	Revuelta, Ignacio\|Moya-Rull, Daniel\|Garcia-Herrera, Adriana\|Rovira, Jordi\|Ayala de la Pena, Francisco\|Misiego, Antonio\|Guzman, Flavia\|Oppenheimer, Federico\|Albanell, Joan\|Campistol, Josep M
PMID:	22245873

123.
Journal:	Clin Cancer Res. 2012 Apr 15;18(8):2316-25.
Title:	The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer.
Author:	Shimizu, Toshio\|Tolcher, Anthony W\|Papadopoulos, Kyriakos P\|Beeram, Muralidhar\|Rasco, Drew W\|Smith, Lon S\|Gunn, Shelly\|Smetzer, Leslie\|Mays, Theresa A\|Kaiser, Brianne\|Wick, Michael J\|Alvarez, Cathy\|Cavazos, Aracely\|Mangold, Gina L\|Patnaik, Amita
PMID:	22261800

124.
Journal:	Cell Cycle. 2012 Feb 1;11(3):594-603.
Title:	mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.
Author:	Zhang, Yanjie\|Zheng, X F Steven
PMID:	22262166

125.
Journal:	Invest New Drugs. 2012 Dec;30(6):2219-25.
Title:	Combination of ATP-competitive mammalian target of rapamycin inhibitors with standard chemotherapy for colorectal cancer.
Author:	Atreya, Chloe E\|Ducker, Gregory S\|Feldman, Morris E\|Bergsland, Emily K\|Warren, Robert S\|Shokat, Kevan M
PMID:	22270257

126.
Journal:	Cancer Res. 2012 Apr 1;72(7):1804-13.
Title:	Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055).
Author:	Holt, Sarah V\|Logie, Armelle\|Davies, Barry R\|Alferez, Denis\|Runswick, Sarah\|Fenton, Sarah\|Chresta, Christine M\|Gu, Yi\|Zhang, Jingchuan\|Wu, Yi-Long\|Wilkinson, Robert W\|Guichard, Sylvie M\|Smith, Paul D
PMID:	22271687

127.
Journal:	Biochem Biophys Res Commun. 2012 Feb 10;418(2):426-32.
Title:	Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
Author:	Guo, Zheng\|Zhou, Yuning\|Evers, B Mark\|Wang, Qingding
PMID:	22285861

128.
Journal:	J Biosci. 2012 Mar;37(1):91-101.
Title:	Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway.
Author:	Wang, Di\|Chen, Jian\|Chen, Hui\|Duan, Zhi\|Xu, Qimei\|Wei, Meiyan\|Wang, Lianghua\|Zhong, Meizuo
PMID:	22357207

129.
Journal:	World J Gastroenterol. 2012 Feb 21;18(7):601-8.
Title:	Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.
Author:	Sipos, Ferenc\|Galamb, Orsolya
PMID:	22363130

130.
Journal:	Clin Cancer Res. 2012 May 1;18(9):2515-25.
Title:	Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Author:	Migliardi, Giorgia\|Sassi, Francesco\|Torti, Davide\|Galimi, Francesco\|Zanella, Eugenia R\|Buscarino, Michela\|Ribero, Dario\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alberto\|Risio, Mauro\|Capussotti, Lorenzo\|Marsoni, Silvia\|Di Nicolantonio, Federica\|Bardelli,
PMID:	22392911

131.
Journal:	BMC Cancer. 2012 Mar 8;12:86.
Title:	Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells.
Author:	Blaser, Benjamin\|Waselle, Laurent\|Dormond-Meuwly, Anne\|Dufour, Marc\|Roulin, Didier\|Demartines, Nicolas\|Dormond, Olivier
PMID:	22401294

132.
Journal:	Gastroenterology. 2012 Jun;142(7):1504-15.e3.
Title:	Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.
Author:	Din, Farhat V N\|Valanciute, Asta\|Houde, Vanessa P\|Zibrova, Daria\|Green, Kevin A\|Sakamoto, Kei\|Alessi, Dario R\|Dunlop, Malcolm G
PMID:	22406476

133.
Journal:	Br J Cancer. 2012 Apr 10;106(8):1386-94.
Title:	The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.
Author:	Haagensen, E J\|Kyle, S\|Beale, G S\|Maxwell, R J\|Newell, D R
PMID:	22415236

134.
Journal:	Onco Targets Ther. 2012;5:21-9.
Title:	Emerging treatment options for the treatment of neuroblastoma: potential role of perifosine.
Author:	Sun, Weili\|Modak, Shakeel
PMID:	22419878

135.
Journal:	Am J Epidemiol. 2012 Apr 1;175(7):653-63.
Title:	Biomarkers of oxidative stress and risk of developing colorectal cancer: a cohort-nested case-control study in the European Prospective Investigation Into Cancer and Nutrition.
Author:	Leufkens, Anke M\|van Duijnhoven, Franzel J B\|Woudt, Sjoukje H S\|Siersema, Peter D\|Jenab, Mazda\|Jansen, Eugene H J M\|Pischon, Tobias\|Tjonneland, Anne\|Olsen, Anja\|Overvad, Kim\|Boutron-Ruault, Marie Christine\|Clavel-Chapelon, Francoise\|Morois, Sophie\|Palli,
PMID:	22422922

136.
Journal:	BMC Cancer. 2012 Mar 26;12:118.
Title:	Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.
Author:	Higurashi, Takuma\|Takahashi, Hirokazu\|Endo, Hiroki\|Hosono, Kunihiro\|Yamada, Eiji\|Ohkubo, Hidenori\|Sakai, Eiji\|Uchiyama, Takashi\|Hata, Yasuo\|Fujisawa, Nobutaka\|Uchiyama, Shiori\|Ezuka, Akiko\|Nagase, Hajime\|Kessoku, Takaomi\|Matsuhashi, Nobuyuki\|Yamanaka, Sho
PMID:	22443173

137.
Journal:	Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15.
Title:	Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.
Author:	Mueller, Annett\|Bachmann, Erika\|Linnig, Monika\|Khillimberger, Katrin\|Schimanski, Carl Christoph\|Galle, Peter R\|Moehler, Markus
PMID:	22543857

138.
Journal:	Oncol Rep. 2012 Jul;28(1):15-20.
Title:	Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Author:	Li, Bo\|Gao, Shuohui\|Wei, Feng\|Bellail, Anita C\|Hao, Chunhai\|Liu, Tongjun
PMID:	22552366

139.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;37(3):233-7.
Title:	[Expression of leptin and p-mTOR and their clinicopathological significance in human colon carcinoma].
Author:	Wang, Di\|Chen, Jian\|Chen, Hui\|Duan, Zhi\|Xu, Qimei\|Wei, Meiyan\|Wang, Lianghua\|Zhong, Meizuo
PMID:	22561505

140.
Journal:	Int J Oncol. 2012 Aug;41(2):583-8.
Title:	Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases.
Author:	Jin, Ketao\|Lan, Huanrong\|Cao, Feilin\|Han, Na\|Xu, Zhenzhen\|Li, Guangliang\|He, Kuifeng\|Teng, Lisong
PMID:	22581265

141.
Journal:	Carcinogenesis. 2012 Sep;33(9):1726-35.
Title:	Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3beta pathway in colon cancer.
Author:	Kumar, Ashok\|Pandurangan, Ashok K\|Lu, Fang\|Fyrst, Henrik\|Zhang, Meng\|Byun, Hoe-Sup\|Bittman, Robert\|Saba, Julie D
PMID:	22581840

142.
Journal:	Curr Pharm Des. 2012;18(26):3853-73.
Title:	Pharmacological control of autophagy: therapeutic perspectives in inflammatory bowel disease and colorectal cancer.
Author:	Garcia-Maurino, Sofia\|Alcaide, Antonio\|Dominguez, Cecilia
PMID:	22632751

143.
Journal:	PLoS One. 2012;7(5):e38033.
Title:	KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors.
Author:	Garrido-Laguna, Ignacio\|Hong, David S\|Janku, Filip\|Nguyen, Ly M\|Falchook, Gerald S\|Fu, Siqing\|Wheler, Jenifer J\|Luthra, Rajyalakshmi\|Naing, Aung\|Wang, Xuemei\|Kurzrock, Razelle
PMID:	22675430

144.
Journal:	PLoS One. 2012;7(5):e37572.
Title:	Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells.
Author:	Wu, Ya C\|Wang, Xiao J\|Yu, Le\|Chan, Francis K L\|Cheng, Alfred S L\|Yu, Jun\|Sung, Joseph J Y\|Wu, William K K\|Cho, Chi H
PMID:	22679478

145.
Journal:	Mol Cancer. 2012 Jun 8;11:38.
Title:	Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.
Author:	Nelson, Laura D\|Bender, Christian\|Mannsperger, Heiko\|Buergy, Daniel\|Kambakamba, Patryk\|Mudduluru, Giridhar\|Korf, Ulrike\|Hughes, Dennis\|Van Dyke, Michael W\|Allgayer, Heike
PMID:	22682314

146.
Journal:	Carcinogenesis. 2012 Sep;33(9):1782-90.
Title:	Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Author:	Gulhati, Pat\|Zaytseva, Yekaterina Y\|Valentino, Joseph D\|Stevens, Payton D\|Kim, Ji Tae\|Sasazuki, Takehiko\|Shirasawa, Senji\|Lee, Eun Y\|Weiss, Heidi L\|Dong, Jianli\|Gao, Tianyan\|Evers, B Mark
PMID:	22696593

147.
Journal:	Mol Cancer Ther. 2012 Sep;11(9):2062-71.
Title:	Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.
Author:	Dienstmann, Rodrigo\|Serpico, Danila\|Rodon, Jordi\|Saura, Cristina\|Macarulla, Teresa\|Elez, Elena\|Alsina, Maria\|Capdevila, Jaume\|Perez-Garcia, Jose\|Sanchez-Olle, Gessami\|Aura, Claudia\|Prudkin, Ludmila\|Landolfi, Stefania\|Hernandez-Losa, Javier\|Vivancos, Ana\|T
PMID:	22723336

148.
Journal:	Mol Biol Rep. 2012 Oct;39(10):9355-60.
Title:	Cancer chemotherapy reduces plasma total polyphenols and total antioxidants capacity in colorectal cancer patients.
Author:	Santiago-Arteche, R\|Muniz, P\|Cavia-Saiz, M\|Garcia-Giron, C\|Garcia-Gonzalez, M\|Llorente-Ayala, Beatriz\|Corral, M J Coma-Del
PMID:	22772457

149.
Journal:	Surgery. 2012 Aug;152(2):277-85.
Title:	Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer.
Author:	Valentino, Joseph D\|Elliott, Victoria A\|Zaytseva, Yekaterina Y\|Rychahou, Piotr G\|Mustain, W Conan\|Wang, Chi\|Gao, Tianyan\|Evers, B Mark
PMID:	22828149

150.
Journal:	Clin Cancer Res. 2012 Sep 15;18(18):4919-30. Epub 2012 Jul 31.
Title:	The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.
Author:	Gaedcke, Jochen\|Grade, Marian\|Camps, Jordi\|Sokilde, Rolf\|Kaczkowski, Bogumil\|Schetter, Aaron J\|Difilippantonio, Michael J\|Harris, Curtis C\|Ghadimi, B Michael\|Moller, Soren\|Beissbarth, Tim\|Ried, Thomas\|Litman, Thomas
PMID:	22850566

151.
Journal:	Evid Based Complement Alternat Med. 2012;2012:871893.
Title:	HRT, Herbal Formula, Induces G(2)/M Cell Cycle Arrest and Apoptosis via Suppressing Akt Signaling Pathway in Human Colon Cancer Cells.
Author:	Yim, Nam-Hui\|Cho, Won-Kyung\|Lee, Ju Hye\|Jung, Young Pil\|Yang, Hye Jin\|Ma, Jin Yeul
PMID:	22899960

152.
Journal:	Expert Opin Investig Drugs. 2012 Dec;21(12):1775-88.
Title:	The promise of mTOR inhibitors in the treatment of colorectal cancer.
Author:	Kim, Dae-Dong\|Eng, Cathy
PMID:	22978346

153.
Journal:	Carcinogenesis. 2012 Dec;33(12):2391-7.
Title:	Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway.
Author:	Iwaya, Takeshi\|Yokobori, Takehiko\|Nishida, Naohiro\|Kogo, Ryunosuke\|Sudo, Tomoya\|Tanaka, Fumiaki\|Shibata, Kohei\|Sawada, Genta\|Takahashi, Yusuke\|Ishibashi, Masahisa\|Wakabayashi, Go\|Mori, Masaki\|Mimori, Koshi
PMID:	22983984

154.
Journal:	BMC Complement Altern Med. 2012 Sep 19;12:160.
Title:	Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.
Author:	Law, Pui-Ching\|Auyeung, Kathy K\|Chan, Lok-Yi\|Ko, Joshua K
PMID:	22992293

155.
Journal:	Cell Cycle. 2012 Nov 1;11(21):3997-4008.
Title:	Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.
Author:	Werneck, Miriam B F\|Hottz, Eugenio\|Bozza, Patricia T\|Viola, Joao P B
PMID:	22992618

156.
Journal:	Curr Med Chem. 2012;19(33):5735-44.
Title:	Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules.
Author:	Efferth, T
PMID:	23033949

157.
Journal:	PLoS One. 2012;7(10):e46716.
Title:	Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Author:	Al-Dwairi, Ahmed\|Pabona, John Mark P\|Simmen, Rosalia C M\|Simmen, Frank A
PMID:	23056418

158.
Journal:	PLoS One. 2012;7(10):e47049.
Title:	Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells.
Author:	Liu, Yong-Qiang\|Cheng, Xin\|Guo, Liang-Xia\|Mao, Chan\|Chen, Yi-Jie\|Liu, Hai-Xia\|Xiao, Qi-Cai\|Jiang, Sheng\|Yao, Zhu-Jun\|Zhou, Guang-Biao
PMID:	23056575

159.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title:	[Predictive biomarkers for anti-EGFR antibodies].
Author:	Bando, Hideaki\|Yoshino, Takayuki
PMID:	23152013

160.
Journal:	BMC Cancer. 2012 Dec 17;12:601.
Title:	Up-regulated expression of l-caldesmon associated with malignancy of colorectal cancer.
Author:	Kim, Kyung-Hee\|Yeo, Seung-Gu\|Kim, Won Ki\|Kim, Dae Yong\|Yeo, Hyun Yang\|Hong, Jun Pyu\|Chang, Hee Jin\|Park, Ji Won\|Kim, Sun Young\|Kim, Byung Chang\|Yoo, Byong Chul
PMID:	23241148

161.
Journal:	BMC Cancer. 2012 Dec 21;12:612.
Title:	Alternative dosing of dual PI3K and MEK inhibition in cancer therapy.
Author:	Jokinen, Elina\|Laurila, Niina\|Koivunen, Jussi P
PMID:	23259591

162.
Journal:	BMC Med Genomics. 2012 Dec 31;5:66.
Title:	Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
Author:	Schlicker, Andreas\|Beran, Garry\|Chresta, Christine M\|McWalter, Gael\|Pritchard, Alison\|Weston, Susie\|Runswick, Sarah\|Davenport, Sara\|Heathcote, Kerry\|Castro, Denis Alferez\|Orphanides, George\|French, Tim\|Wessels, Lodewyk F A
PMID:	23272949

163.
Journal:	Colorectal Cancer. 2012 Oct;1(5).
Title:	Future of targeted agents in metastatic colorectal cancer.
Author:	Burotto, Mauricio\|Hartley, Marion L\|Marshall, John L\|Pishvaian, Michael J
PMID:	24273599

164.
Journal:	J Nat Med. 2013 Jan;67(1):17-26.
Title:	Investigation of the extracts from Bidens pilosa Linn. var. radiata Sch. Bip. for antioxidant activities and cytotoxicity against human tumor cells.
Author:	Wu, Jianguo\|Wan, Zhongxian\|Yi, Jun\|Wu, Yanbin\|Peng, Wei\|Wu, Jinzhong
PMID:	22382861

165.
Journal:	Fundam Clin Pharmacol. 2013 Aug;27(4):434-42.
Title:	Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation.
Author:	Chu, Celine\|Noel-Hudson, Marie-Sophie\|Boige, Valerie\|Goere, Diane\|Marion, Sylvie\|Polrot, Melanie\|Bigot, Ludovic\|Gonin, Patrick\|Farinotti, Robert\|Bonhomme-Faivre, Laurence
PMID:	22458846

166.
Journal:	Food Chem. 2013 Jan 1;136(1):26-33.
Title:	SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway.
Author:	Son, Mi Kwon\|Jung, Kyung Hee\|Hong, Sang-Won\|Lee, Hee-Seung\|Zheng, Hong-Mei\|Choi, Myung-Joo\|Seo, Ju Hyeon\|Suh, Jun-Kyu\|Hong, Soon-Sun
PMID:	23017388

167.
Journal:	Tumour Biol. 2013 Apr;34(2):683-93.
Title:	Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.
Author:	Ding, Zhen-Yu\|Liu, Gui-Hong\|Olsson, Birgit\|Sun, Xiao-Feng
PMID:	23188704

168.
Journal:	J Urol. 2013 Jul;190(1):302-10.
Title:	Involvement of heregulin/HER3 in the primary culture of human urothelial cancer.
Author:	Okuyama, Hiroaki\|Yoshida, Takahiro\|Endo, Hiroko\|Nakayama, Masashi\|Nonomura, Norio\|Nishimura, Kazuo\|Inoue, Masahiro
PMID:	23313199

169.
Journal:	Cell Signal. 2013 Jan;25(1):66-73.
Title:	Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells.
Author:	Gu, Shuchen\|Kounenidakis, Michalis\|Schmidt, Eva-Maria\|Deshpande, Divija\|Alkahtani, Saad\|Alarifi, Saud\|Foller, Michael\|Alevizopoulos, Konstantinos\|Lang, Florian\|Stournaras, Christos
PMID:	23316499

170.
Journal:	Asian Pac J Trop Med. 2013 Jan;6(1):11-9.
Title:	Free radical scavenging property and antiproliferative activity of Rhodiola imbricata Edgew extracts in HT-29 human colon cancer cells.
Author:	Senthilkumar, Ravichandran\|Parimelazhagan, Thangaraj\|Chaurasia, Om Prakash\|Srivastava, R B
PMID:	23317880

171.
Journal:	Curr Nutr Rep. 2013 Mar;2(1):19-26.
Title:	The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach.
Author:	Weijenberg, Matty P\|Hughes, Laura A E\|Bours, Martijn J L\|Simons, Colinda C J M\|van Engeland, Manon\|van den Brandt, Piet A
PMID:	23396869

172.
Journal:	Food Chem. 2013 Jun 1;138(2-3):808-13.
Title:	In vitro biological activity of essential oils and isolated furanosesquiterpenes from the neglected vegetable Smyrnium olusatrum L. (Apiaceae).
Author:	Quassinti, Luana\|Bramucci, Massimo\|Lupidi, Giulio\|Barboni, Luciano\|Ricciutelli, Massimo\|Sagratini, Gianni\|Papa, Fabrizio\|Caprioli, Giovanni\|Petrelli, Dezemona\|Vitali, Luca A\|Vittori, Sauro\|Maggi, Filippo
PMID:	23411181

173.
Journal:	Mol Cancer Ther. 2013 May;12(5):598-609.
Title:	Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth.
Author:	Ponnurangam, Sivapriya\|Standing, David\|Rangarajan, Parthasarathy\|Subramaniam, Dharmalingam
PMID:	23427297

174.
Journal:	Autophagy. 2013 May;9(5):697-713.
Title:	Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
Author:	Raina, Komal\|Agarwal, Chapla\|Wadhwa, Ritambhara\|Serkova, Natalie J\|Agarwal, Rajesh
PMID:	23445752

175.
Journal:	Int J Cancer. 2013 Aug 15;133(4):984-96.
Title:	Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer.
Author:	Kim, Areumnuri\|Lee, Jung-Eun\|Lee, Seung-Sook\|Kim, Cherin\|Lee, Sun-Joo\|Jang, Won-Suk\|Park, Sunhoo
PMID:	23475782

176.
Journal:	Cell Physiol Biochem. 2013;31(2-3):209-18.
Title:	miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma.
Author:	Zhong, Ming\|Bian, Zhengqian\|Wu, Zhiyong
PMID:	23486085

177.
Journal:	PLoS One. 2013;8(3):e58089.
Title:	Utilization of quantitative in vivo pharmacology approaches to assess combination effects of everolimus and irinotecan in mouse xenograft models of colorectal cancer.
Author:	Bradshaw-Pierce, Erica L\|Pitts, Todd M\|Kulikowski, Gillian\|Selby, Heather\|Merz, Andrea L\|Gustafson, Daniel L\|Serkova, Natalie J\|Eckhardt, S Gail\|Weekes, Colin D
PMID:	23520486

178.
Journal:	Biochem Biophys Res Commun. 2013 Apr 19;433(4):420-5.
Title:	Involvement of PI3K-AKT-mTOR pathway in protein kinase CKII inhibition-mediated senescence in human colon cancer cells.
Author:	Park, Ji Hye\|Kim, Jin Joo\|Bae, Young-Seuk
PMID:	23523798

179.
Journal:	Clin Cancer Res. 2013 May 15;19(10):2688-98.
Title:	Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.
Author:	Coffee, Erin M\|Faber, Anthony C\|Roper, Jatin\|Sinnamon, Mark J\|Goel, Gautam\|Keung, Lily\|Wang, Wei Vivian\|Vecchione, Loredana\|de Vriendt, Veerle\|Weinstein, Barbara J\|Bronson, Roderick T\|Tejpar, Sabine\|Xavier, Ramnik J\|Engelman, Jeffrey A\|Martin, Eric S\|Hung
PMID:	23549875

180.
Journal:	Biochem Biophys Res Commun. 2013 May 3;434(2):352-6.
Title:	Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells.
Author:	Wang, Yuli\|Liu, Yueyong\|Lu, Jing\|Zhang, Pengju\|Wang, Yunshan\|Xu, Yangyang\|Wang, Zeran\|Mao, Jian-Hua\|Wei, Guangwei
PMID:	23558291

181.
Journal:	Clin Res Hepatol Gastroenterol. 2013 Apr;37(2):134-41.
Title:	Digestive neuroendocrine tumors (DNET): the era of targeted therapies.
Author:	Boussaha, Tarek\|Rougier, Philippe\|Taieb, Julien\|Lepere, Celine
PMID:	23562338

182.
Journal:	Neoplasma. 2013;60(4):364-72.
Title:	Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways.
Author:	Yang, J\|Li, T Z\|Xu, G H\|Luo, B B\|Chen, Y X\|Zhang, T
PMID:	23581408

183.
Journal:	Int J Oncol. 2013 Jun;42(6):2134-40.
Title:	Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.
Author:	Manne, Nandini D P K\|Lima, M\|Enos, R T\|Wehner, P\|Carson, J A\|Blough, Eric
PMID:	23589074

184.
Journal:	Evid Based Complement Alternat Med. 2013;2013:974313.
Title:	Activation of AMP-Activated Protein Kinase alpha and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells.
Author:	Cho, Sung-Yun\|Lee, Hyo-Jeong\|Lee, Hyo-Jung\|Jung, Deok-Beom\|Kim, Hyunseok\|Sohn, Eun Jung\|Kim, Bonglee\|Jung, Ji Hoon\|Kwon, Byoung-Mog\|Kim, Sung-Hoon
PMID:	23589723

185.
Journal:	PLoS One. 2013 Apr 9;8(4):e60709.
Title:	mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Author:	Deming, Dustin A\|Leystra, Alyssa A\|Farhoud, Mohammed\|Nettekoven, Laura\|Clipson, Linda\|Albrecht, Dawn\|Washington, Mary Kay\|Sullivan, Ruth\|Weichert, Jamey P\|Halberg, Richard B
PMID:	23593290

186.
Journal:	Int J Cancer. 2013 Nov;133(9):2089-101.
Title:	Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Author:	Martinelli, Erika\|Troiani, Teresa\|D'Aiuto, Elena\|Morgillo, Floriana\|Vitagliano, Donata\|Capasso, Anna\|Costantino, Sarah\|Ciuffreda, Loreta Pia\|Merolla, Francesco\|Vecchione, Loredana\|De Vriendt, Veerle\|Tejpar, Sabine\|Nappi, Anna\|Sforza, Vincenzo\|Martini, Giu
PMID:	23629727

187.
Journal:	Int J Oncol. 2013 Jul;43(1):141-50.
Title:	Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells.
Author:	Chen, Hui-Jye\|Jiang, Yi-Lin\|Lin, Chung-Ming\|Tsai, Shih-Chang\|Peng, Shu-Fen\|Fushiya, Shinji\|Hour, Mann-Jen\|Yang, Jai-Sing
PMID:	23677180

188.
Journal:	Environ Toxicol Pharmacol. 2013 Sep;36(2):339-46.
Title:	Evaluation of antiproliferative and antioxidant activities of the organic extract and its polar fractions from the Mediterranean gorgonian Eunicella singularis.
Author:	Deghrigue, Monia\|Dellai, Afef\|Akremi, Najoua\|Le Morvan, Valerie\|Robert, Jacques\|Bouraoui, Abderrahman
PMID:	23712134

189.
Journal:	Asian Pac J Cancer Prev. 2013;14(4):2201-5.
Title:	Potential targets for prevention of colorectal cancer: a focus on PI3K/Akt/mTOR and Wnt pathways.
Author:	Pandurangan, Ashok Kumar
PMID:	23725112

190.
Journal:	Mol Cancer Res. 2013 Sep;11(9):1040-50.
Title:	Epithelial-specific deletion of 11beta-HSD2 hinders Apcmin/+ mouse tumorigenesis.
Author:	Jiang, Li\|Yang, Shilin\|Yin, Huiyong\|Fan, Xiaofeng\|Wang, Suwan\|Yao, Bing\|Pozzi, Ambra\|Chen, Xiaoping\|Harris, Raymond C\|Zhang, Ming-Zhi
PMID:	23741059

191.
Journal:	Clin Cancer Res. 2013 Jul 15;19(14):3987-95.
Title:	Phase II study of everolimus in patients with metastatic colorectal adenocarcinoma previously treated with bevacizumab-, fluoropyrimidine-, oxaliplatin-, and irinotecan-based regimens.
Author:	Ng, Kimmie\|Tabernero, Josep\|Hwang, Jimmy\|Bajetta, Emilio\|Sharma, Sunil\|Del Prete, Salvatore A\|Arrowsmith, Edward R\|Ryan, David P\|Sedova, Michaela\|Jin, Jin\|Malek, Kamel\|Fuchs, Charles S
PMID:	23743569

192.
Journal:	Oncol Lett. 2013 May;5(5):1554-1558.
Title:	13,14-bis(cis-3,5-dimethyl-1-piperazinyl)-beta-elemene, a novel beta-elemene derivative, shows potent antitumor activities via inhibition of mTOR in human breast cancer cells.
Author:	Ding, Xiao-Fei\|Shen, Mao\|Xu, Li-Ying\|Dong, Jin-Hua\|Chen, Guang
PMID:	23761818

193.
Journal:	Hum Pathol. 2013 Oct;44(10):2089-96.
Title:	Clinical impacts of mammalian target of rapamycin expression in human colorectal cancers.
Author:	Alqurashi, Naif\|Gopalan, Vinod\|Smith, Robert A\|Lam, Alfred King Y
PMID:	23773481

194.
Journal:	Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title:	Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
Author:	Giampieri, Riccardo\|Scartozzi, Mario\|Del Prete, Michela\|Maccaroni, Elena\|Bittoni, Alessandro\|Faloppi, Luca\|Bianconi, Maristella\|Cecchini, Luca\|Cascinu, Stefano
PMID:	23806981

195.
Journal:	BMC Cancer. 2013 Jul 1;13:321.
Title:	Overexpression of peptide deformylase in breast, colon, and lung cancers.
Author:	Randhawa, Harsharan\|Chikara, Shireen\|Gehring, Drew\|Yildirim, Tuba\|Menon, Jyotsana\|Reindl, Katie M
PMID:	23815882

196.
Journal:	PLoS One. 2013 Jun 27;8(6):e67258.
Title:	Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.
Author:	Fang, Douglas D\|Zhang, Cathy C\|Gu, Yin\|Jani, Jitesh P\|Cao, Joan\|Tsaparikos, Konstantinos\|Yuan, Jing\|Thiel, Melissa\|Jackson-Fisher, Amy\|Zong, Qing\|Lappin, Patrick B\|Hayashi, Tomoko\|Schwab, Richard B\|Wong, Anthony\|John-Baptiste, Annette\|Bagrodia, Shubha\|Los
PMID:	23826249

197.
Journal:	Eur J Cancer. 2013 Oct;49(15):3311-9.
Title:	Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression.
Author:	Saxena, Ashish\|Shoeb, Mohammad\|Ramana, Kota V\|Srivastava, Satish K
PMID:	23827854

198.
Journal:	Anticancer Agents Med Chem. 2013 Dec;13(10):1540-50.
Title:	Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric.
Author:	Einbond, Linda Saxe\|Mighty, Jason\|Kashiwazaki, Ryota\|Figueroa, Mario\|Jalees, Filza\|Acuna, Ulyana Munoz\|Le Gendre, Onica\|Foster, David A\|Kennelly, Edward J
PMID:	23848206

199.
Journal:	Oncotarget. 2013 Aug;4(8):1185-98.
Title:	Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Author:	Saturno, Grazia\|Valenti, Melanie\|De Haven Brandon, Alexis\|Thomas, George V\|Eccles, Suzanne\|Clarke, Paul A\|Workman, Paul
PMID:	23852390

200.
Journal:	Cancer Discov. 2013 Oct;3(10):1156-71.
Title:	PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.
Author:	Tan, Jing\|Li, Zhimei\|Lee, Puay Leng\|Guan, Peiyong\|Aau, Mei Yee\|Lee, Shuet Theng\|Feng, Min\|Lim, Cheryl Zihui\|Lee, Eric Yong Jing\|Wee, Zhen Ning\|Lim, Yaw Chyn\|Karuturi, R K Murthy\|Yu, Qiang
PMID:	23887393

201.
Journal:	ACS Chem Biol. 2013 Oct 18;8(10):2145-50.
Title:	Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
Author:	Kim, Hyung-Gu\|Tan, Li\|Weisberg, Ellen L\|Liu, Feiyang\|Canning, Peter\|Choi, Hwan Geun\|Ezell, Scott A\|Wu, Hong\|Zhao, Zheng\|Wang, Jinhua\|Mandinova, Anna\|Griffin, James D\|Bullock, Alex N\|Liu, Qingsong\|Lee, Sam W\|Gray, Nathanael S
PMID:	23899692

202.
Journal:	J Cell Mol Med. 2013 Oct;17(10):1316-24.
Title:	Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway.
Author:	Luo, Wenjuan\|Wang, Xiaoli\|Zheng, Lei\|Zhan, Yingzhuan\|Zhang, Dongdong\|Zhang, Jie\|Zhang, Yanmin
PMID:	23905676

203.
Journal:	Cancer Med. 2013 Jun;2(3):277-85.
Title:	Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Townsend, Amanda R\|Wrin, Joseph W\|Wilson, Kate\|Weickhardt, Andrew\|Simes, Robert J\|Murone, Carmel\|Tebbutt, Niall C
PMID:	23930204

204.
Journal:	PLoS One. 2013 Jul 23;8(7):e68817.
Title:	Genotype directed therapy in murine mismatch repair deficient tumors.
Author:	Kucherlapati, Melanie H\|Esfahani, Shadi\|Habibollahi, Peiman\|Wang, Junning\|Still, Eric R\|Bronson, Roderick T\|Mahmood, Umar\|Kucherlapati, Raju S
PMID:	23935891

205.
Journal:	Invest New Drugs. 2013 Dec;31(6):1505-13.
Title:	Phase I clinical trial of lenalidomide in combination with temsirolimus in patients with advanced cancer.
Author:	Ganesan, Prasanth\|Piha-Paul, Sarina\|Naing, Aung\|Falchook, Gerald\|Wheler, Jennifer\|Janku, Filip\|Zinner, Ralph\|Laday, Shell\|Kies, Merrill\|Tsimberidou, Apostolia M
PMID:	23982248

206.
Journal:	PLoS One. 2013 Aug 22;8(8):e73175.
Title:	Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma.
Author:	Wang, Quan\|Wei, Feng\|Li, Chunsheng\|Lv, Guoyue\|Wang, Guangyi\|Liu, Tongjun\|Bellail, Anita C\|Hao, Chunhai
PMID:	23991179

207.
Journal:	Carcinogenesis. 2013 Dec;34(12):2814-22.
Title:	Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
Author:	Banerjee, Nivedita\|Kim, Hyemee\|Talcott, Stephen\|Mertens-Talcott, Susanne
PMID:	23996930

208.
Journal:	Mol Cell Biol. 2013 Nov;33(22):4594-605.
Title:	Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells.
Author:	Wen, Yang-An\|Stevens, Payton D\|Gasser, Michael L\|Andrei, Romina\|Gao, Tianyan
PMID:	24061475

209.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2857-63.
Title:	Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations.
Author:	Ganesan, Prasanth\|Janku, Filip\|Naing, Aung\|Hong, David S\|Tsimberidou, Apostolia M\|Falchook, Gerald S\|Wheler, Jennifer J\|Piha-Paul, Sarina A\|Fu, Siqing\|Stepanek, Vanda M\|Lee, J Jack\|Luthra, Rajyalakshmi\|Overman, Michael J\|Kopetz, E Scott\|Wolff, Robert A\|Ku
PMID:	24092809

210.
Journal:	Chem Biodivers. 2013 Oct;10(10):1876-86.
Title:	Chemical composition and biological activities of the essential oil of Athanasia brownii Hochr. (Asteraceae) endemic to Madagascar.
Author:	Rasoanaivo, Philippe\|Fortune Randriana, Richard\|Maggi, Filippo\|Nicoletti, Marcello\|Quassinti, Luana\|Bramucci, Massimo\|Lupidi, Giulio\|Petrelli, Dezemona\|Vitali, Luca A\|Papa, Fabrizio\|Vittori, Sauro
PMID:	24130030

211.
Journal:	Rev Med Liege. 2013 Sep;68(9):444-9.
Title:	[Metformin, an antidiabetic molecule with anti-cancer properties].
Author:	Beck, E\|Scheen, A J
PMID:	24180199

212.
Journal:	Oncotarget. 2013 Nov;4(11):1948-62.
Title:	Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1.
Author:	Francipane, Maria Giovanna\|Lagasse, Eric
PMID:	24185040

213.
Journal:	Front Oncol. 2013 Nov 15;3:281.
Title:	Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF.
Author:	Thiel, Alexandra\|Ristimaki, Ari
PMID:	24298448

214.
Journal:	PLoS One. 2013 Dec 12;8(12):e82982.
Title:	Comparative analysis of radiosensitizers for K-RAS mutant rectal cancers.
Author:	Kleiman, Laura B\|Krebs, Angela M\|Kim, Stephen Y\|Hong, Theodore S\|Haigis, Kevin M
PMID:	24349411

215.
Journal:	J Cancer Prev. 2013 Sep;18(3):264-70.
Title:	Quercetin Regulates Sestrin 2-AMPK-mTOR Signaling Pathway and Induces Apoptosis via Increased Intracellular ROS in HCT116 Colon Cancer Cells.
Author:	Kim, Guen Tae\|Lee, Se Hee\|Kim, Young Min
PMID:	25337554

216.
Journal:	Oncogene. 2014 Mar 20;33(12):1590-600.
Title:	Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors.
Author:	Ducker, G S\|Atreya, C E\|Simko, J P\|Hom, Y K\|Matli, M R\|Benes, C H\|Hann, B\|Nakakura, E K\|Bergsland, E K\|Donner, D B\|Settleman, J\|Shokat, K M\|Warren, R S
PMID:	23542178

217.
Journal:	Cell Signal. 2014 Jan;26(1):102-9.
Title:	MicroRNA-451 regulates AMPK/mTORC1 signaling and fascin1 expression in HT-29 colorectal cancer.
Author:	Chen, Min-Bin\|Wei, Mu-Xin\|Han, Jun-Yi\|Wu, Xiao-Yang\|Li, Chen\|Wang, Jian\|Shen, Wei\|Lu, Pei-Hua
PMID:	23899558

218.
Journal:	Ann Surg Oncol. 2014 Jan;21(1):179-88.
Title:	Significance of mTOR signaling and its inhibitor against cancer stem-like cells in colorectal cancer.
Author:	Cai, Zerong\|Ke, Jia\|He, Xiaosheng\|Yuan, Ruixue\|Chen, Yufeng\|Wu, Xianrui\|Wang, Lei\|Wang, Jianping\|Lan, Ping\|Wu, Xiaojian
PMID:	23907312

219.
Journal:	Oncogene. 2014 Jul 10;33(28):3677-87.
Title:	CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation.
Author:	Nie, J\|Liu, L\|Xing, G\|Zhang, M\|Wei, R\|Guo, M\|Li, X\|Xie, P\|Li, L\|He, F\|Han, W\|Zhang, L
PMID:	23995790

220.
Journal:	Cancer Discov. 2014 Jan;4(1):42-52.
Title:	mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Author:	Faber, Anthony C\|Coffee, Erin M\|Costa, Carlotta\|Dastur, Anahita\|Ebi, Hiromichi\|Hata, Aaron N\|Yeo, Alan T\|Edelman, Elena J\|Song, Youngchul\|Tam, Ah Ting\|Boisvert, Jessica L\|Milano, Randy J\|Roper, Jatin\|Kodack, David P\|Jain, Rakesh K\|Corcoran, Ryan B\|Rivera,
PMID:	24163374

221.
Journal:	Biochim Biophys Acta. 2014 Feb;1843(2):372-86.
Title:	CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.
Author:	Ellis, Blake C\|Graham, Lloyd D\|Molloy, Peter L
PMID:	24184209

222.
Journal:	Cancer Res. 2014 Jan 1;74(1):330-40.
Title:	Cancer usurps skeletal muscle as an energy repository.
Author:	Luo, Yi\|Yoneda, Junya\|Ohmori, Hitoshi\|Sasaki, Takamitsu\|Shimbo, Kazutaka\|Eto, Sachise\|Kato, Yumiko\|Miyano, Hiroshi\|Kobayashi, Tsuyoshi\|Sasahira, Tomonori\|Chihara, Yoshitomo\|Kuniyasu, Hiroki
PMID:	24197136

223.
Journal:	Cancer Res. 2014 Feb 15;74(4):1153-65.
Title:	Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.
Author:	Hong, Bo\|Prabhu, Varun V\|Zhang, Shengliang\|van den Heuvel, A Pieter J\|Dicker, David T\|Kopelovich, Levy\|El-Deiry, Wafik S
PMID:	24247721

224.
Journal:	Biochem Biophys Res Commun. 2014 Jan 10;443(2):406-12.
Title:	Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014.
Author:	Huo, Hai-zhong\|Zhou, Zhi-yuan\|Wang, Bing\|Qin, Jian\|Liu, Wen-yong\|Gu, Yan
PMID:	24309100

225.
Journal:	J Cell Sci. 2014 Feb 15;127(Pt 4):788-800.
Title:	Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation.
Author:	Cope, Claire L\|Gilley, Rebecca\|Balmanno, Kathryn\|Sale, Matthew J\|Howarth, Karen D\|Hampson, Mark\|Smith, Paul D\|Guichard, Sylvie M\|Cook, Simon J
PMID:	24363449

226.
Journal:	Oncotarget. 2014 Jan 15;5(1):49-66.
Title:	mTOR pathway in colorectal cancer: an update.
Author:	Francipane, Maria Giovanna\|Lagasse, Eric
PMID:	24393708

227.
Journal:	Biochem Pharmacol. 2014 Mar 15;88(2):150-7.
Title:	Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway.
Author:	Li, Yuhua\|Sun, Yang\|Fan, Lei\|Zhang, Feng\|Meng, Jin\|Han, Jin\|Guo, Xin\|Zhang, Dian\|Zhang, Rong\|Yue, Zhenggang\|Mei, Qibing
PMID:	24462916

228.
Journal:	Acta Pharmacol Sin. 2014 Mar;35(3):394-400.
Title:	OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
Author:	Arafa, El-shaimaa A\|Abdelazeem, Ahmed H\|Arab, Hany H\|Omar, Hany A
PMID:	24464048

229.
Journal:	Asian Pac J Cancer Prev. 2014;15(2):551-60.
Title:	Signal transducer and activator of transcription 3 - a promising target in colitis-associated cancer.
Author:	Pandurangan, Ashok Kumar\|Esa, Norhaizan Mohd
PMID:	24568457

230.
Journal:	Clin Cancer Res. 2014 Apr 15;20(8):2126-35.
Title:	A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Author:	Hight, Matthew R\|Cheung, Yiu-Yin\|Nickels, Michael L\|Dawson, Eric S\|Zhao, Ping\|Saleh, Samir\|Buck, Jason R\|Tang, Dewei\|Washington, M Kay\|Coffey, Robert J\|Manning, H Charles
PMID:	24573549

231.
Journal:	PLoS One. 2014 Feb 19;9(2):e89388.
Title:	FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
Author:	Jardim, Denis L\|Wheler, Jennifer J\|Hess, Kenneth\|Tsimberidou, Apostolia M\|Zinner, Ralph\|Janku, Filip\|Subbiah, Vivek\|Naing, Aung\|Piha-Paul, Sarina A\|Westin, Shannon N\|Roy-Chowdhuri, Sinchita\|Meric-Bernstam, Funda\|Hong, David S
PMID:	24586741

232.
Journal:	Ann Transplant. 2014 Mar 7;19:124-8.
Title:	Determining eligibility for and preparation to kidney transplantation of a patient with Lynch syndrome--a case report and literature review.
Author:	Gozdowska, Jolanta\|Bieniasz, Monika\|Wszola, Michal\|Kieszek, Rafal\|Domagala, Piotr\|Drozdowski, Jakub\|Tomaszek, Aleksandra\|Kwiatkowski, Artur\|Chmura, Andrzej\|Durlik, Magdalena
PMID:	24614524

233.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):769-81.
Title:	Temsirolimus and chloroquine cooperatively exhibit a potent antitumor effect against colorectal cancer cells.
Author:	Kaneko, Manabu\|Nozawa, Hiroaki\|Hiyoshi, Masaya\|Tada, Noriko\|Murono, Koji\|Nirei, Takako\|Emoto, Shigenobu\|Kishikawa, Junko\|Iida, Yuuki\|Sunami, Eiji\|Tsuno, Nelson H\|Kitayama, Joji\|Takahashi, Koki\|Watanabe, Toshiaki
PMID:	24619662

234.
Journal:	PLoS One. 2014 Mar 25;9(3):e92966.
Title:	Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation.
Author:	Tsoli, Maria\|Schweiger, Martina\|Vanniasinghe, Anne S\|Painter, Arran\|Zechner, Rudolf\|Clarke, Stephen\|Robertson, Graham
PMID:	24667661

235.
Journal:	Neoplasia. 2014 Feb;16(2):147-57.
Title:	BMX acts downstream of PI3K to promote colorectal cancer cell survival and pathway inhibition sensitizes to the BH3 mimetic ABT-737.
Author:	Potter, Danielle S\|Kelly, Paul\|Denneny, Olive\|Juvin, Veronique\|Stephens, Len R\|Dive, Caroline\|Morrow, Christopher J
PMID:	24709422

236.
Journal:	Curr Cancer Drug Targets. 2014;14(4):323-36.
Title:	Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.
Author:	Derry, Molly M\|Somasagara, Ranganatha R\|Raina, Komal\|Kumar, Sushil\|Gomez, Joe\|Patel, Manisha\|Agarwal, Rajesh\|Agarwal, Chapla
PMID:	24724981

237.
Journal:	PLoS One. 2014 Apr 17;9(4):e95588.
Title:	Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability.
Author:	Seo, Bo Ram\|Min, Kyoung-Jin\|Cho, Il Je\|Kim, Sang Chan\|Kwon, Taeg Kyu
PMID:	24743574

238.
Journal:	Mol Cancer Ther. 2014 Jun;13(6):1399-409.
Title:	Moguntinones--new selective inhibitors for the treatment of human colorectal cancer.
Author:	Maderer, Annett\|Plutizki, Stanislav\|Kramb, Jan-Peter\|Gopfert, Katrin\|Linnig, Monika\|Khillimberger, Katrin\|Ganser, Christopher\|Lauermann, Eva\|Dannhardt, Gerd\|Galle, Peter R\|Moehler, Markus
PMID:	24743703

239.
Journal:	World J Gastroenterol. 2014 Apr 21;20(15):4178-88.
Title:	Targeting mTOR network in colorectal cancer therapy.
Author:	Wang, Xiao-Wen\|Zhang, Yan-Jie
PMID:	24764656

240.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S634-9.
Title:	Genetic variations in STK11, PRKAA1, and TSC1 associated with prognosis for patients with colorectal cancer.
Author:	Lee, Soo Jung\|Kang, Byung Woog\|Chae, Yee Soo\|Kim, Hye Jin\|Park, Su Yeon\|Park, Jun Seok\|Choi, Gyu Seog\|Jeon, Hyo-Sung\|Lee, Won Kee\|Kim, Jong Gwang
PMID:	24770722

241.
Journal:	PLoS One. 2014 May 8;9(5):e96418.
Title:	ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid.
Author:	Zhang, Haiyuan\|Lei, Yunlong\|Yuan, Ping\|Li, Lingjun\|Luo, Chao\|Gao, Rui\|Tian, Jun\|Feng, Zuohua\|Nice, Edouard C\|Sun, Jun
PMID:	24810758

242.
Journal:	ACS Chem Biol. 2014 Aug 15;9(8):1755-63.
Title:	Sequence-selective molecular recognition of the C-terminal CaaX-boxes of Rheb and related Ras-proteins by synthetic receptors.
Author:	Duppe, Peter M\|Tran Thi Phuong, Thao\|Autzen, Jasmin\|Schopel, Miriam\|Yip, King Tuo\|Stoll, Raphael\|Scherkenbeck, Jurgen
PMID:	24856002

243.
Journal:	Biochem Pharmacol. 2014 Aug 1;90(3):265-75.
Title:	Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells.
Author:	Zhang, Jian-wei\|Zhang, Shan-shan\|Song, Jian-rui\|Sun, Kai\|Zong, Chen\|Zhao, Qiu-dong\|Liu, Wen-ting\|Li, Rong\|Wu, Meng-chao\|Wei, Li-xin
PMID:	24858802

244.
Journal:	PLoS One. 2014 May 29;9(5):e97719.
Title:	Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.
Author:	Lou, Yun-feng\|Zou, Zheng-zhi\|Chen, Pin-jia\|Huang, Guo-bin\|Li, Bin\|Zheng, De-qing\|Yu, Xiu-rong\|Luo, Xiao-yong
PMID:	24874286

245.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S703-10.
Title:	LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer.
Author:	He, Tsung-Ying\|Tsai, Lung-Hung\|Huang, Chi-Chou\|Chou, Ming-Chih\|Lee, Huei
PMID:	24879590

246.
Journal:	Br J Cancer. 2014 Jul 15;111(2):375-85.
Title:	Dichloroacetate induces autophagy in colorectal cancer cells and tumours.
Author:	Lin, G\|Hill, D K\|Andrejeva, G\|Boult, J K R\|Troy, H\|Fong, A-C L F W T\|Orton, M R\|Panek, R\|Parkes, H G\|Jafar, M\|Koh, D-M\|Robinson, S P\|Judson, I R\|Griffiths, J R\|Leach, M O\|Eykyn, T R\|Chung, Y-L
PMID:	24892448

247.
Journal:	PLoS One. 2014 Jun 11;9(6):e99254.
Title:	Alpha-2-glycoprotein 1(AZGP1) regulates biological behaviors of LoVo cells by down-regulating mTOR signaling pathway and endogenous fatty acid synthesis.
Author:	Chang, Ligong\|Tian, Xiaoqiang\|Lu, Yinghui\|Jia, Min\|Wu, Peng\|Huang, Peilin
PMID:	24918753

248.
Journal:	Oncol Lett. 2014 Jun;7(6):2047-2052.
Title:	Inhibition of ovarian cancer cell proliferation by Pien Tze Huang via the AKT-mTOR pathway.
Author:	He, Fan\|Wu, Hui-Ni\|Cai, Mu-Yan\|Li, Chang-Peng\|Zhang, Xin\|Wan, Quan\|Tang, Shuang-Bo\|Cheng, Jian-Ding
PMID:	24932287

249.
Journal:	Int J Med Sci. 2014 Jun 8;11(8):841-9.
Title:	Activation of the PI3K/Akt/mTOR/p70S6K pathway is involved in S100A4-induced viability and migration in colorectal cancer cells.
Author:	Wang, Haiyan\|Duan, Liang\|Zou, Zhengyu\|Li, Huan\|Yuan, Shimei\|Chen, Xian\|Zhang, Yunyuan\|Li, Xueru\|Sun, Hui\|Zha, He\|Zhang, Yan\|Zhou, Lan
PMID:	24936148

250.
Journal:	Cancer. 2014 Nov 15;120(22):3446-56.
Title:	The MAPK pathway across different malignancies: a new perspective.
Author:	Burotto, Mauricio\|Chiou, Victoria L\|Lee, Jung-Min\|Kohn, Elise C
PMID:	24948110

251.
Journal:	Autophagy. 2014 Sep;10(9):1495-508.
Title:	Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells.
Author:	Xie, Chuan-Ming\|Liu, Xiao-Yu\|Sham, Kathy W Y\|Lai, Josie M Y\|Cheng, Christopher H K
PMID:	24955726

252.
Journal:	Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.
Title:	Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Mullany, Lila E\|Penney, Rosalind B\|Wolff, Roger K
PMID:	24959314

253.
Journal:	PLoS One. 2014 Jun 24;9(6):e99631.
Title:	Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
Author:	Chiang, En-Pei Isabel\|Tsai, Shu-Yao\|Kuo, Yueh-Hsiung\|Pai, Man-Hui\|Chiu, Hsi-Lin\|Rodriguez, Raymond L\|Tang, Feng-Yao
PMID:	24960186

254.
Journal:	Asian Pac J Cancer Prev. 2014;15(11):4589-94.
Title:	DEPTOR expression negatively correlates with mTORC1 activity and tumor progression in colorectal cancer.
Author:	Lai, Er-Yong\|Chen, Zhen-Guo\|Zhou, Xuan\|Fan, Xiao-Rong\|Wang, Hua\|Lai, Ping-Lin\|Su, Yong-Chun\|Zhang, Bai-Yu\|Bai, Xiao-Chun\|Li, Yun-Feng
PMID:	24969890

255.
Journal:	Int J Oncol. 2014 Sep;45(3):1036-42.
Title:	Phloroglucinol induces apoptosis through the regulation of insulin-like growth factor 1 receptor signaling pathways in human colon cancer HT-29 cells.
Author:	Kang, Mi-Hye\|Kim, In-Hye\|Nam, Taek-Jeong
PMID:	24970012

256.
Journal:	Oncotarget. 2014 Jul 15;5(13):5138-52.
Title:	ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
Author:	Lee, Hyunji\|Lee, Hyunjung\|Chin, Hyunjung\|Kim, Kyoungmi\|Lee, Daekee
PMID:	24970817

257.
Journal:	Biomed Pharmacother. 2014 Jun;68(5):527-35.
Title:	NF-kappaB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Author:	Li, Meng\|Wang, Xiu'e\|Liu, Ming\|Qi, Xin\|Li, Jing
PMID:	24986326

258.
Journal:	Autophagy. 2014 Aug;10(8):1454-65.
Title:	ATG4B promotes colorectal cancer growth independent of autophagic flux.
Author:	Liu, Pei-Feng\|Leung, Chung-Man\|Chang, Yu-Hsiang\|Cheng, Jin-Shiung\|Chen, Jih-Jung\|Weng, Chung-Jeu\|Tsai, Kuo-Wang\|Hsu, Chien-Jen\|Liu, Yen-Chen\|Hsu, Ping-Chi\|Pan, Hung-Wei\|Shu, Chih-Wen
PMID:	24991826

259.
Journal:	Med Oncol. 2014 Aug;31(8):92.
Title:	The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer.
Author:	Wen, Xiaoxia\|Zhu, Jianjun\|Dong, Lei\|Chen, Yao
PMID:	25023051

260.
Journal:	Oncol Rep. 2014 Oct;32(4):1427-34.
Title:	Differential protein expression and novel biomarkers related to 5-FU resistance in a 3D colorectal adenocarcinoma model.
Author:	Lee, Sang-Hak\|Nam, Jae Kook\|Park, Jong-Kook\|Lee, Joo-Ho\|Min, Do Sik\|Kuh, Hyo-Jeong
PMID:	25050539

261.
Journal:	PLoS One. 2014 Jul 24;9(7):e103298.
Title:	Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Author:	Ye, Qiurong\|Zheng, Ying\|Fan, Songqing\|Qin, Zailong\|Li, Nan\|Tang, Anliu\|Ai, Feiyan\|Zhang, Xuemei\|Bian, Yanhui\|Dang, Wei\|Huang, Jing\|Zhou, Ming\|Zhou, Yanhong\|Xiong, Wei\|Yan, Qun\|Ma, Jian\|Li, Guiyuan
PMID:	25057912

262.
Journal:	Int J Nanomedicine. 2014 Jul 16;9:3403-11.
Title:	Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways.
Author:	Chen, Jiezhong\|Shao, Renfu\|Li, Li\|Xu, Zhi Ping\|Gu, Wenyi
PMID:	25075187

263.
Journal:	Biomed Pharmacother. 2014 Jul;68(6):721-7.
Title:	The PI3K/Akt pathway in colitis associated colon cancer and its chemoprevention with celecoxib, a Cox-2 selective inhibitor.
Author:	Setia, Shruti\|Nehru, Bimla\|Sanyal, Sankar Nath
PMID:	25107843

264.
Journal:	Oncol Lett. 2014 Sep;8(3):1080-1086.
Title:	Clinical significance of aberrant mammalian target of rapamycin expression in stage IIIB colon cancer.
Author:	Wen, Meiling\|Li, Baoxiu\|Cao, Xiaofei\|Weng, Chengyin\|Wu, Yong\|Fang, Xisheng\|Zhang, Xiaoshi\|Liu, Guolong
PMID:	25120661

265.
Journal:	Carcinogenesis. 2014 Oct;35(10):2314-20.
Title:	A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
Author:	D'Angelo, Leonarda\|Piazzi, Giulia\|Pacilli, Annalisa\|Prossomariti, Anna\|Fazio, Chiara\|Montanaro, Lorenzo\|Graziani, Giulia\|Fogliano, Vincenzo\|Munarini, Alessandra\|Bianchi, Francesca\|Belluzzi, Andrea\|Bazzoli, Franco\|Ricciardiello, Luigi
PMID:	25123131

266.
Journal:	Biochem Biophys Res Commun. 2014 Sep 5;451(4):587-91.
Title:	PGE2-induced colon cancer growth is mediated by mTORC1.
Author:	Dufour, Marc\|Faes, Seraina\|Dormond-Meuwly, Anne\|Demartines, Nicolas\|Dormond, Olivier
PMID:	25128827

267.
Journal:	PLoS One. 2014 Sep 23;9(9):e108193.
Title:	3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.
Author:	McKinley, Eliot T\|Zhao, Ping\|Coffey, Robert J\|Washington, M Kay\|Manning, H Charles
PMID:	25247710

268.
Journal:	Oncotarget. 2014 Sep 15;5(17):7936-44.
Title:	Mutant NRASQ61 shares signaling similarities across various cancer types--potential implications for future therapies.
Author:	Vujic, Igor\|Posch, Christian\|Sanlorenzo, Martina\|Yen, Adam J\|Tsumura, Aaron\|Kwong, Andrew\|Feichtenschlager, Valentin\|Lai, Kevin\|Arneson, Douglas V\|Rappersberger, Klemens\|Ortiz-Urda, Susana M
PMID:	25277205

269.
Journal:	Br J Cancer. 2014 Nov 11;111(10):1932-44.
Title:	A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.
Author:	Brana, I\|Berger, R\|Golan, T\|Haluska, P\|Edenfield, J\|Fiorica, J\|Stephenson, J\|Martin, L P\|Westin, S\|Hanjani, P\|Jones, M B\|Almhanna, K\|Wenham, R M\|Sullivan, D M\|Dalton, W S\|Gunchenko, A\|Cheng, J D\|Siu, L L\|Gray, J E
PMID:	25290091

270.
Journal:	J Clin Invest. 2014 Dec;124(12):5398-410.
Title:	Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
Author:	Funato, Yosuke\|Yamazaki, Daisuke\|Mizukami, Shin\|Du, Lisa\|Kikuchi, Kazuya\|Miki, Hiroaki
PMID:	25347473

271.
Journal:	Cell Death Dis. 2014 Oct 30;5:e1504.
Title:	Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer.
Author:	Song, X\|Kim, S-Y\|Zhang, L\|Tang, D\|Bartlett, D L\|Kwon, Y T\|Lee, Y J
PMID:	25356873

272.
Journal:	Neoplasia. 2014 Oct 23;16(10):845-60.
Title:	Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.
Author:	Grasso, Silvina\|Tristante, Elena\|Saceda, Miguel\|Carbonell, Pablo\|Mayor-Lopez, Leticia\|Carballo-Santana, Mar\|Carrasco-Garcia, Estefania\|Rocamora-Reverte, Lourdes\|Garcia-Morales, Pilar\|Carballo, Fernando\|Ferragut, Jose A\|Martinez-Lacaci, Isabel
PMID:	25379021

273.
Journal:	Sci Signal. 2014 Nov 11;7(351):ra107.
Title:	Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Author:	Belmont, Peter J\|Jiang, Ping\|McKee, Trevor D\|Xie, Tao\|Isaacson, Jason\|Baryla, Nicole E\|Roper, Jatin\|Sinnamon, Mark J\|Lee, Nathan V\|Kan, Julie L C\|Guicherit, Oivin\|Wouters, Bradly G\|O'Brien, Catherine A\|Shields, David\|Olson, Peter\|VanArsdale, Todd\|Weinrich
PMID:	25389372

274.
Journal:	PLoS One. 2014 Nov 12;9(11):e111814.
Title:	Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors.
Author:	Cheng, Tzu-Chun\|Lai, Ching-Shu\|Chung, Min-Ching\|Kalyanam, Nagabhushanam\|Majeed, Muhammed\|Ho, Chi-Tang\|Ho, Yuan-Soon\|Pan, Min-Hsiung
PMID:	25389774

275.
Journal:	PLoS One. 2014 Nov 17;9(11):e113037.
Title:	Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Author:	Pitts, Todd M\|Newton, Timothy P\|Bradshaw-Pierce, Erica L\|Addison, Rebecca\|Arcaroli, John J\|Klauck, Peter J\|Bagby, Stacey M\|Hyatt, Stephanie L\|Purkey, Alicia\|Tentler, John J\|Tan, Aik Choon\|Messersmith, Wells A\|Eckhardt, S Gail\|Leong, Stephen
PMID:	25401499

276.
Journal:	Biomed Pharmacother. 2014 Oct;68(8):1023-9.
Title:	Upregulation of MAPK/Erk and PI3K/Akt pathways in ulcerative colitis-associated colon cancer.
Author:	Setia, Shruti\|Nehru, Bimla\|Sanyal, Sankar Nath
PMID:	25443414

277.
Journal:	Cancer Biol Ther. 2014;15(12):1646-57.
Title:	Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author:	Booth, Laurence\|Cruickshanks, Nichola\|Tavallai, Seyedmehrad\|Roberts, Jane L\|Peery, Matthew\|Poklepovic, Andrew\|Dent, Paul
PMID:	25482938

278.
Journal:	Eur Rev Med Pharmacol Sci. 2014;18(21):3183-8.
Title:	Expression of Notch-signaling pathway in familial adenomatous polyposis and its clinical significance.
Author:	Xie, Z-Y\|Gong, L-B\|Zhang, W-T\|Lv, X-P
PMID:	25487926

279.
Journal:	Cancer Cell. 2014 Nov 10;26(5):601-3.
Title:	mTORC1 gRABs the Golgi.
Author:	Sanchez-Gurmaches, Joan\|Guertin, David A
PMID:	25517745

280.
Journal:	Am J Cancer Res. 2014 Nov 19;4(6):824-37. eCollection 2014.
Title:	Establishment of genetically diverse patient-derived xenografts of colorectal cancer.
Author:	Burgenske, Danielle M\|Monsma, David J\|Dylewski, Dawna\|Scott, Stephanie B\|Sayfie, Aaron D\|Kim, Donald G\|Luchtefeld, Martin\|Martin, Katie R\|Stephenson, Paul\|Hostetter, Galen\|Dujovny, Nadav\|MacKeigan, Jeffrey P
PMID:	25520871

281.
Journal:	Dev Reprod. 2014 Dec;18(4):225-31.
Title:	Biphasic activity of chloroquine in human colorectal cancer cells.
Author:	Park, Deokbae\|Lee, Youngki
PMID:	25949192

282.
Journal:	Leukemia. 2015 Jan;29(1):27-37.
Title:	Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Author:	Weisberg, Ellen\|Nonami, Atsushi\|Chen, Zhao\|Liu, Feiyang\|Zhang, Jianming\|Sattler, Martin\|Nelson, Erik\|Cowens, Kristen\|Christie, Amanda L\|Mitsiades, Constantine\|Wong, Kwok-Kin\|Liu, Qingsong\|Gray, Nathanael\|Griffin, James D
PMID:	24791855

283.
Journal:	Mol Carcinog. 2015 Oct;54(10):1096-109.
Title:	Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Author:	Li, Weidong\|Hua, Baojin\|Saud, Shakir M\|Lin, Hongsheng\|Hou, Wei\|Matter, Matthias S\|Jia, Libin\|Colburn, Nancy H\|Young, Matthew R
PMID:	24838344

284.
Journal:	Int J Biol Markers. 2015 Feb 24;30(1):e73-80.
Title:	An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab.
Author:	Sclafani, Francesco\|Rimassa, Lorenza\|Colombo, Piergiuseppe\|Destro, Annarita\|Stinco, Sergio\|Lutman, Fabio R\|Carnaghi, Carlo\|Beretta, Giordano\|Zanello, Alessandro\|Roncalli, Massimo\|Giordano, Laura\|Santoro, Armando
PMID:	24980447

285.
Journal:	Int J Cancer. 2015 Apr 1;136(7):1515-27.
Title:	Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer.
Author:	Gargalionis, Antonios N\|Korkolopoulou, Penelope\|Farmaki, Elena\|Piperi, Christina\|Dalagiorgou, Georgia\|Adamopoulos, Christos\|Levidou, Georgia\|Saetta, Angelica\|Fragkou, Paraskevi\|Tsioli, Panagiota\|Kiaris, Hippokratis\|Zizi-Serbetzoglou, Adamantia\|Karavokyros
PMID:	25123959

286.
Journal:	J Cell Physiol. 2015 Apr;230(4):930-46.
Title:	Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Author:	Won, Shen-Jeu\|Yen, Cheng-Hsin\|Liu, Hsiao-Sheng\|Wu, Shan-Ying\|Lan, Sheng-Hui\|Jiang-Shieh, Ya-Fen\|Lin, Chun-Nan\|Su, Chun-Li
PMID:	25216025

287.
Journal:	Tumour Biol. 2015 Feb;36(2):1091-7.
Title:	Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9.
Author:	E, Jifu\|Xing, Junjie\|Gong, Haifeng\|He, Jian\|Zhang, Wei
PMID:	25326806

288.
Journal:	Nature. 2015 Jan 22;517(7535):497-500.
Title:	mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Author:	Faller, William J\|Jackson, Thomas J\|Knight, John Rp\|Ridgway, Rachel A\|Jamieson, Thomas\|Karim, Saadia A\|Jones, Carolyn\|Radulescu, Sorina\|Huels, David J\|Myant, Kevin B\|Dudek, Kate M\|Casey, Helen A\|Scopelliti, Alessandro\|Cordero, Julia B\|Vidal, Marcos\|Pende,
PMID:	25383520

289.
Journal:	J Cell Mol Med. 2015 Jan;19(1):74-81.
Title:	Hypothesis: cell signalling influences age-related risk of colorectal cancer.
Author:	Bordonaro, Michael\|Lazarova, Darina L
PMID:	25388238

290.
Journal:	Nat Chem Biol. 2015 Jan;11(1):58-63.
Title:	GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors.
Author:	Thorne, Curtis A\|Wichaidit, Chonlarat\|Coster, Adam D\|Posner, Bruce A\|Wu, Lani F\|Altschuler, Steven J
PMID:	25402767

291.
Journal:	Cancer Prev Res (Phila). 2015 Feb;8(2):139-48.
Title:	Combined use of vitamin D3 and metformin exhibits synergistic chemopreventive effects on colorectal neoplasia in rats and mice.
Author:	Li, Wan\|Wang, Qi-Long\|Liu, Xia\|Dong, Shu-Hong\|Li, Hong-Xia\|Li, Chun-Yang\|Guo, Li-Shu\|Gao, Jing-Miao\|Berger, Nathan A\|Li, Li\|Ma, Lan\|Wu, Yong-Jie
PMID:	25416412

292.
Journal:	Am J Pathol. 2015 Feb;185(2):399-408.
Title:	mTOR and PDGF pathway blockade inhibits liver metastasis of colorectal cancer by modulating the tumor microenvironment.
Author:	Yuge, Ryo\|Kitadai, Yasuhiko\|Shinagawa, Kei\|Onoyama, Mieko\|Tanaka, Shinji\|Yasui, Wataru\|Chayama, Kazuaki
PMID:	25478811

293.
Journal:	J Control Release. 2015 Feb 10;199:114-21.
Title:	Targeted therapy of colorectal neoplasia with rapamycin in peptide-labeled pegylated octadecyl lithocholate micelles.
Author:	Khondee, Supang\|Rabinsky, Emily F\|Owens, Scott R\|Joshi, Bishnu P\|Qiu, Zhen\|Duan, Xiyu\|Zhao, Lili\|Wang, Thomas D
PMID:	25483425

294.
Journal:	Cancer Lett. 2015 Feb 28;357(2):582-90.
Title:	Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.
Author:	Chen, Yu-Hsuan\|Wei, Ming-Feng\|Wang, Chun-Wei\|Lee, Hsiao-Wei\|Pan, Shiow-Lin\|Gao, Ming\|Kuo, Sung-Hsin\|Cheng, Ann-Lii\|Teng, Che-Ming
PMID:	25497009

295.
Journal:	Mol Med Rep. 2015 Apr;11(4):3160-6.
Title:	Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC3 pancreatic carcinoma cells.
Author:	Su, Chin-Cheng
PMID:	25516264

296.
Journal:	Nat Rev Drug Discov. 2015 Jan;14(1):14-5.
Title:	Cancer: mTOR inhibition curbs colorectal cancer.
Author:	Crunkhorn, Sarah
PMID:	25549586

297.
Journal:	Inflamm Bowel Dis. 2015 Feb;21(2):287-96.
Title:	Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer.
Author:	Khare, Vineeta\|Dammann, Kyle\|Asboth, Mario\|Krnjic, Anita\|Jambrich, Manuela\|Gasche, Christoph
PMID:	25569743

298.
Journal:	Oncology. 2015;88(5):309-19.
Title:	Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
Author:	Shibuya, Norisuke\|Inoue, Ken-ichi\|Tanaka, Genki\|Akimoto, Kazumi\|Kubota, Keiichi
PMID:	25591719

299.
Journal:	Invest New Drugs. 2015 Jun;33(3):720-8.
Title:	Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer.
Author:	Do, Khanh\|Speranza, Giovanna\|Bishop, Rachel\|Khin, Sonny\|Rubinstein, Larry\|Kinders, Robert J\|Datiles, Manuel\|Eugeni, Michelle\|Lam, Michael H\|Doyle, L Austin\|Doroshow, James H\|Kummar, Shivaani
PMID:	25637165

300.
Journal:	Cell Oncol (Dordr). 2015 Apr;38(2):119-29.
Title:	Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib.
Author:	Gotink, Kristy J\|Rovithi, Maria\|de Haas, Richard R\|Honeywell, Richard J\|Dekker, Henk\|Poel, Dennis\|Azijli, Kaamar\|Peters, Godefridus J\|Broxterman, Henk J\|Verheul, Henk M W
PMID:	25665527

301.
Journal:	Cancer Lett. 2015 Apr 28;360(1):68-75.
Title:	The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway.
Author:	Zhou, Wei\|He, Mei-Rong\|Jiao, Hong-Li\|He, Liu-Qing\|Deng, Dan-Ling\|Cai, Juan-Juan\|Xiao, Zhi-Yuan\|Ye, Ya-Ping\|Ding, Yan-Qing\|Liao, Wen-Ting\|Liu, Si-De
PMID:	25667121

302.
Journal:	Tumour Biol. 2015 Jul;36(7):5641-8.
Title:	AZD-4547 exerts potent cytostatic and cytotoxic activities against fibroblast growth factor receptor (FGFR)-expressing colorectal cancer cells.
Author:	Yao, Ting-Jing\|Zhu, Jin-Hai\|Peng, De-Feng\|Cui, Zhen\|Zhang, Chao\|Lu, Pei-hua
PMID:	25691251

303.
Journal:	Cancer Biol Ther. 2015;16(3):460-5.
Title:	Tumor suppression by resistant maltodextrin, Fibersol-2.
Author:	So, Eui Young\|Ouchi, Mutsuko\|Cuesta-Sancho, Sara\|Olson, Susan Losee\|Reif, Dirk\|Shimomura, Kazuhiro\|Ouchi, Toru
PMID:	25692338

304.
Journal:	Cancer Biol Ther. 2015;16(1):34-42.
Title:	The preclinical evaluation of the dual mTORC1/2 inhibitor INK-128 as a potential anti-colorectal cancer agent.
Author:	Li, Chen\|Cui, Jian-Feng\|Chen, Min-Bin\|Liu, Chao-Ying\|Liu, Feng\|Zhang, Qian-De\|Zou, Jian\|Lu, Pei-Hua
PMID:	25692620

305.
Journal:	Mol Cancer Ther. 2015 Apr;14(4):1048-56.
Title:	Biomarker signatures correlate with clinical outcome in refractory metastatic colorectal cancer patients receiving bevacizumab and everolimus.
Author:	Liu, Yingmiao\|Starr, Mark D\|Brady, John C\|Rushing, Christel\|Bulusu, Anuradha\|Pang, Herbert\|Honeycutt, Wanda\|Amara, Anthony\|Altomare, Ivy\|Uronis, Hope E\|Hurwitz, Herbert I\|Nixon, Andrew B
PMID:	25695956

306.
Journal:	J Cell Physiol. 2015 Sep;230(9):2281-98.
Title:	Nexavar/Stivarga and viagra interact to kill tumor cells.
Author:	Tavallai, Mehrad\|Hamed, Hossein A\|Roberts, Jane L\|Cruickshanks, Nichola\|Chuckalovcak, John\|Poklepovic, Andrew\|Booth, Laurence\|Dent, Paul
PMID:	25704960

307.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

308.
Journal:	Int J Mol Med. 2015 May;35(5):1301-8.
Title:	miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway.
Author:	Zhang, Xiangliang\|Shi, Huijuan\|Tang, Hongsheng\|Fang, Zhiyuan\|Wang, Jiping\|Cui, Shuzhong
PMID:	25760926

309.
Journal:	J Cell Biochem. 2015 Sep;116(9):1837-47.
Title:	Oncogenic and Therapeutic Targeting of PTEN Loss in Bone Malignancies.
Author:	Xi, Yongming\|Chen, Yan
PMID:	25773992

310.
Journal:	Hum Pathol. 2015 May;46(5):753-60.
Title:	Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers.
Author:	Choi, Mi Ryoung\|Yoo, Nam Jin\|An, Chang Hyeok\|Lee, Sug Hyung
PMID:	25776026

311.
Journal:	Biomed Pharmacother. 2015 Mar;70:28-32.
Title:	Functional promoter rs2295080 T>G variant in MTOR gene is associated with risk of colorectal cancer in a Chinese population.
Author:	Xu, Ming\|Gao, Yan\|Yu, Tingting\|Wang, Jirong\|Cheng, Liang\|Cheng, Lifang\|Cheng, Dawei\|Zhu, Baoli
PMID:	25776475

312.
Journal:	Mol Med Rep. 2015 Jul;12(1):1189-96.
Title:	Nitrogen permease regulator-like 2 enhances sensitivity to oxaliplatin in colon cancer cells.
Author:	Liu, Ming-Na\|Liu, Ai-Yun\|Du, Ya-Ju\|Pei, Feng-Hua\|Wang, Xin-Hong\|Chen, Jing\|Liu, Dan\|Liu, Bing-Rong
PMID:	25777765

313.
Journal:	Cancer Biol Ther. 2015;16(5):733-42.
Title:	Differential regulation of autophagy and cell viability by ceramide species.
Author:	Cruickshanks, Nichola\|Roberts, Jane L\|Bareford, M Danielle\|Tavallai, Mehrad\|Poklepovic, Andrew\|Booth, Laurence\|Spiegel, Sarah\|Dent, Paul
PMID:	25803131

314.
Journal:	PLoS One. 2015 Mar 25;10(3):e0121046.
Title:	Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect.
Author:	Lu, Chung-Ling\|Qin, Lili\|Liu, Hsin-Chen\|Candas, Demet\|Fan, Ming\|Li, Jian Jian
PMID:	25807077

315.
Journal:	Cell Prolif. 2015 Jun;48(3):338-47.
Title:	Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy.
Author:	Li, Yuyin\|Zhang, Li\|Zhou, Jie\|Luo, Shenheng\|Huang, Rui\|Zhao, Changcai\|Diao, Aipo
PMID:	25809873

316.
Journal:	Bioinorg Chem Appl. 2015;2015:920143.
Title:	Oxaliplatin analogues with carboxy derivatives of boldine with enhanced antioxidant activity.
Author:	Mellado, Marco\|Jara, Carlos\|Astudillo, David\|Villena, Joan\|Reveco, Patricio G\|Thomet, Franz A
PMID:	25814916

317.
Journal:	BMC Cancer. 2015 Apr 8;15:240.
Title:	HGUE-C-1 is an atypical and novel colon carcinoma cell line.
Author:	Grasso, Silvina\|Martinez-Lacaci, Isabel\|Barbera, Victor Manuel\|Castillejo, Adela\|Soto, Jose Luis\|Gallego-Plazas, Javier\|Lopez-Riquelme, Natividad\|Garcia-Morales, Pilar\|Mata-Balaguer, Trinidad\|Ferragut, Jose Antonio\|Saceda, Miguel
PMID:	25885658

318.
Journal:	J Cell Physiol. 2015 Dec;230(12):2973-80.
Title:	Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines.
Author:	Refolo, Maria Grazia\|D'Alessandro, Rosalba\|Malerba, Natascia\|Laezza, Chiara\|Bifulco, Maurizio\|Messa, Caterina\|Caruso, Maria Gabriella\|Notarnicola, Maria\|Tutino, Valeria
PMID:	25893829

319.
Journal:	Oncotarget. 2015 Jun 20;6(17):15332-47.
Title:	Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
Author:	Sharon, Chetna\|Baranwal, Somesh\|Patel, Nirmita J\|Rodriguez-Agudo, Daniel\|Pandak, William M\|Majumdar, Adhip P N\|Krystal, Geoffrey\|Patel, Bhaumik B
PMID:	25895029

320.
Journal:	Cancer Res. 2015 Jun 15;75(12):2434-44.
Title:	IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Author:	Bartolome, Ruben A\|Garcia-Palmero, Irene\|Torres, Sofia\|Lopez-Lucendo, Maria\|Balyasnikova, Irina V\|Casal, J Ignacio
PMID:	25896327

321.
Journal:	PLoS One. 2015 Apr 23;10(4):e0119015.
Title:	mLST8 Promotes mTOR-Mediated Tumor Progression.
Author:	Kakumoto, Kyoko\|Ikeda, Jun-Ichiro\|Okada, Masato\|Morii, Eiichi\|Oneyama, Chitose
PMID:	25906254

322.
Journal:	Mol Cancer Ther. 2015 Jun;14(6):1504-16.
Title:	Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.
Author:	Senkowski, Wojciech\|Zhang, Xiaonan\|Olofsson, Maria Hagg\|Isacson, Ruben\|Hoglund, Urban\|Gustafsson, Mats\|Nygren, Peter\|Linder, Stig\|Larsson, Rolf\|Fryknas, Marten
PMID:	25911689

323.
Journal:	Cancer Discov. 2015 Jul;5(7):768-781.
Title:	Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer.
Author:	Wiegering, Armin\|Uthe, Friedrich W\|Jamieson, Thomas\|Ruoss, Yvonne\|Huttenrauch, Melanie\|Kuspert, Maritta\|Pfann, Christina\|Nixon, Colin\|Herold, Steffi\|Walz, Susanne\|Taranets, Lyudmyla\|Germer, Christoph-Thomas\|Rosenwald, Andreas\|Sansom, Owen J\|Eilers, Martin
PMID:	25934076

324.
Journal:	Biochem Biophys Res Commun. 2015 Jun 19;462(1):38-45.
Title:	The natural product peiminine represses colorectal carcinoma tumor growth by inducing autophagic cell death.
Author:	Lyu, Qing\|Tou, Fangfang\|Su, Hong\|Wu, Xiaoyong\|Chen, Xinyi\|Zheng, Zhi
PMID:	25935480

325.
Journal:	Cell Signal. 2015 Aug;27(8):1557-68.
Title:	Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
Author:	Bommer, Ulrich-Axel\|Iadevaia, Valentina\|Chen, Jiezhong\|Knoch, Bianca\|Engel, Martin\|Proud, Christopher G
PMID:	25936523

326.
Journal:	Oncotarget. 2015 Jun 10;6(16):13962-77.
Title:	AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
Author:	Mi, Wenting\|Ye, Qing\|Liu, Side\|She, Qing-Bai
PMID:	25961827

327.
Journal:	Mol Med Rep. 2015 Sep;12(3):3446-3452.
Title:	Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways.
Author:	Han, Yong-Seok\|Lee, Jun Hee\|Lee, Sang Hun
PMID:	25998232

328.
Journal:	Cell Cycle. 2015;14(16):2667-76.
Title:	Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation.
Author:	Fazolini, Narayana P B\|Cruz, Andre L S\|Werneck, Miriam B F\|Viola, Joao P B\|Maya-Monteiro, Clarissa M\|Bozza, Patricia T
PMID:	26017929

329.
Journal:	Asian Pac J Cancer Prev. 2015;16(10):4161-8.
Title:	Obesity and Obese-related Chronic Low-grade Inflammation in Promotion of Colorectal Cancer Development.
Author:	Pietrzyk, Lukasz\|Torres, Anna\|Maciejewski, Ryszard\|Torres, Kamil
PMID:	26028066

330.
Journal:	Int J Clin Exp Pathol. 2015 Apr 1;8(4):3882-91. eCollection 2015.
Title:	Expression and clinical significances of Beclin1, LC3 and mTOR in colorectal cancer.
Author:	Wu, Shuhua\|Sun, Chenbo\|Tian, Dong\|Li, Yangyang\|Gao, Xiangqian\|He, Shuang\|Li, Tangyue
PMID:	26097572

331.
Journal:	Ann Clin Biochem. 2015 Nov;52(Pt 6):690-2.
Title:	The Mendelian colorectal cancer syndromes.
Author:	Tomlinson, Ian
PMID:	26169059

332.
Journal:	Oncol Lett. 2015 Jul;10(1):277-282.
Title:	Expression and clinical significance of mammalian target of rapamycin/P70 ribosomal protein S6 kinase signaling pathway in human colorectal carcinoma tissue.
Author:	Lu, Qingjun\|Wang, Jieshu\|Yu, Gang\|Guo, Tianhua\|Hu, Chun\|Ren, Peng
PMID:	26171014

333.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2175-86.
Title:	Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.
Author:	Raja, Meera\|Zverev, Matt\|Seipel, Katja\|Williams, Geraint T\|Clarke, Alan R\|Shaw, Paul H S
PMID:	26206338

334.
Journal:	Cancer Chemother Pharmacol. 2015 Sep;76(3):575-86.
Title:	Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells.
Author:	Yang, Dan\|Qu, Jinglei\|Qu, Xiujuan\|Cao, Yubo\|Xu, Ling\|Hou, Kezuo\|Feng, Wanyu\|Liu, Yunpeng
PMID:	26208739

335.
Journal:	Sci Transl Med. 2015 Jul 29;7(298):298ra117.
Title:	Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice.
Author:	Cai, Hong\|Scott, Edwina\|Kholghi, Abeer\|Andreadi, Catherine\|Rufini, Alessandro\|Karmokar, Ankur\|Britton, Robert G\|Horner-Glister, Emma\|Greaves, Peter\|Jawad, Dhafer\|James, Mark\|Howells, Lynne\|Ognibene, Ted\|Malfatti, Michael\|Goldring, Christopher\|Kitteringham
PMID:	26223300

336.
Journal:	Endocr Relat Cancer. 2015 Oct;22(5):831-40.
Title:	Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy.
Author:	Hedrick, Erik\|Lee, Syng-Ook\|Doddapaneni, Ravi\|Singh, Mandip\|Safe, Stephen
PMID:	26229035

337.
Journal:	Radiother Oncol. 2015 Aug;116(2):214-20.
Title:	A phase I-II study on the combination of rapamycin and short course radiotherapy in rectal cancer.
Author:	Buijsen, Jeroen\|van den Bogaard, Jorgen\|Jutten, Barry\|Belgers, Eric\|Sosef, Meindert\|Leijtens, Jeroen W A\|Beets, Geerard L\|Jansen, Rob L H\|Riedl, Robert G\|Clarijs, Ruud\|Lammering, Guido\|Lambin, Philippe
PMID:	26253949

338.
Journal:	Oncotarget. 2015 Sep 15;6(27):24448-62.
Title:	miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR.
Author:	Li, Wenhua\|Chang, Jinjia\|Wang, Shanshan\|Liu, Xinyang\|Peng, Junjie\|Huang, Dan\|Sun, Menghong\|Chen, Zhiyu\|Zhang, Wen\|Guo, Weijian\|Li, Jin
PMID:	26259252

339.
Journal:	Int J Clin Exp Pathol. 2015 Jun 1;8(6):7009-15. eCollection 2015.
Title:	Expression of phospho-mTOR kinase is abundant in colorectal cancer and associated with left-sided tumor localization.
Author:	Melling, Nathaniel\|Simon, Ronald\|Izbicki, Jakob R\|Terracciano, Luigi M\|Bokemeyer, Carsten\|Sauter, Guido\|Marx, Andreas H
PMID:	26261591

340.
Journal:	Tumour Biol. 2015 Sep;36(9):6673-5.
Title:	AdipoRon: a possible drug for colorectal cancer prevention?
Author:	Malih, Sara\|Najafi, Rezvan
PMID:	26282004

341.
Journal:	Oncogenesis. 2015 Aug 24;4:e164.
Title:	Diacylglycerol kinase-zeta regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1.
Author:	Torres-Ayuso, P\|Tello-Lafoz, M\|Merida, I\|Avila-Flores, A
PMID:	26302180

342.
Journal:	Eur J Pharmacol. 2015 Oct 15;765:217-27.
Title:	Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
Author:	Pal, Ipsita\|Parida, Sheetal\|Prashanth Kumar, B N\|Banik, Payel\|Kumar Dey, Kaushik\|Chakraborty, Sandipan\|Bhutia, Sujit K\|Mandal, Mahitosh
PMID:	26306675

343.
Journal:	Hum Pathol. 2015 Nov;46(11):1752-9.
Title:	Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
Author:	Shuhua, Wu\|Chenbo, Sun\|Yangyang, Li\|Xiangqian, Gao\|Shuang, He\|Tangyue, Li\|Dong, Tian
PMID:	26363527

344.
Journal:	Oncotarget. 2015 Oct 20;6(32):33500-11.
Title:	Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.
Author:	Chang, Jian\|Vacher, Jean\|Yao, Bing\|Fan, Xiaofeng\|Zhang, Bixiang\|Harris, Raymond C\|Zhang, Ming-Zhi
PMID:	26378024

345.
Journal:	Biochem Biophys Res Commun. 2015 Oct 23;466(3):547-53.
Title:	DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600.
Author:	Wu, Ling\|Zhang, Jiansheng\|Wu, Huiguo\|Han, Enkun
PMID:	26381179

346.
Journal:	Mol Nutr Food Res. 2015 Dec;59(12):2511-22.
Title:	Se-Allylselenocysteine induces autophagy by modulating the AMPK/mTOR signaling pathway and epigenetic regulation of PCDH17 in human colorectal adenocarcinoma cells.
Author:	Wu, Jia-Ching\|Wang, Fang-Zong\|Tsai, Mei-Ling\|Lo, Chih-Yu\|Badmaev, Vladimir\|Ho, Chi-Tang\|Wang, Ying-Jan\|Pan, Min-Hsiung
PMID:	26395119

347.
Journal:	Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1317-26.
Title:	PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.
Author:	Chen, Jiezhong\|Shao, Renfu\|Li, Feng\|Monteiro, Michael\|Liu, Jun-Ping\|Xu, Zhi Ping\|Gu, Wenyi
PMID:	26399781

348.
Journal:	Int J Mol Sci. 2015 Sep 23;16(9):22976-88.
Title:	Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	26404261

349.
Journal:	Oncotarget. 2015 Oct 13;6(31):31272-83.
Title:	Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors.
Author:	Serrano-Heras, Gemma\|Cuenca-Lopez, Maria Dolores\|Montero, Juan Carlos\|Corrales-Sanchez, Veronica\|Morales, Jorge Carlos\|Nunez, Luz-Elena\|Moris, Francisco\|Pandiella, Atanasio\|Ocana, Alberto
PMID:	26418718

350.
Journal:	Asian Pac J Cancer Prev. 2015;16(15):6549-56.
Title:	Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
Author:	Wee, Lee Heng\|Morad, Noor Azian\|Aan, Goon Jo\|Makpol, Suzana\|Wan Ngah, Wan Zurinah\|Mohd Yusof, Yasmin Anum
PMID:	26434873

351.
Journal:	Cancer Cell Int. 2015 Oct 9;15:96.
Title:	Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy.
Author:	Ramasamy, Thamil Selvee\|Ayob, Ain Zubaidah\|Myint, Hsu Hsu Lynn\|Thiagarajah, Sharmanee\|Amini, Farahnaz
PMID:	26457069

352.
Journal:	PLoS One. 2015 Oct 15;10(10):e0140479.
Title:	Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092.
Author:	Yu, Yi\|Savage, Ronald E\|Eathiraj, Sudharshan\|Meade, Justin\|Wick, Michael J\|Hall, Terence\|Abbadessa, Giovanni\|Schwartz, Brian
PMID:	26469692

353.
Journal:	J Control Release. 2015 Dec 28;220(Pt A):160-168.
Title:	Cytotoxicity of PEGylated liposomes co-loaded with novel pro-apoptotic drug NCL-240 and the MEK inhibitor cobimetinib against colon carcinoma in vitro.
Author:	Sriraman, Shravan Kumar\|Geraldo, Vananelia\|Luther, Ed\|Degterev, Alexei\|Torchilin, Vladimir
PMID:	26497930

354.
Journal:	Am J Chin Med. 2015;43(7):1471-86.
Title:	Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway.
Author:	Meng, Yan\|Lin, Zhao-Min\|Ge, Nan\|Zhang, Deng-Lu\|Huang, Jie\|Kong, Feng
PMID:	26503559

355.
Journal:	Oncotarget. 2015 Dec 8;6(39):42334-44.
Title:	Mutational profiling of colorectal cancers with microsatellite instability.
Author:	Lin, Elaine I\|Tseng, Li-Hui\|Gocke, Christopher D\|Reil, Stacy\|Le, Dung T\|Azad, Nilofer S\|Eshleman, James R
PMID:	26517354

356.
Journal:	World J Gastroenterol. 2015 Nov 7;21(41):11740-7.
Title:	Neuroendocrine differentiation: The mysterious fellow of colorectal cancer.
Author:	Kleist, Britta\|Poetsch, Micaela
PMID:	26556999

357.
Journal:	Onco Targets Ther. 2015 Nov 2;8:3185-92.
Title:	Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.
Author:	Cheng, Lei\|Xia, Zuguang\|Bian, Xinyu\|Li, Guangchao\|Hu, Jing\|Cao, Ya\|Wang, Qing\|Qian, Xiaoping
PMID:	26586952

358.
Journal:	Mar Drugs. 2015 Nov 19;13(11):6962-76.
Title:	Salternamide A Suppresses Hypoxia-Induced Accumulation of HIF-1alpha and Induces Apoptosis in Human Colorectal Cancer Cells.
Author:	Bach, Duc-Hiep\|Kim, Seong-Hwan\|Hong, Ji-Young\|Park, Hyen Joo\|Oh, Dong-Chan\|Lee, Sang Kook
PMID:	26610526

359.
Journal:	PLoS One. 2015 Dec 17;10(12):e0144708.
Title:	Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author:	Briffa, Romina\|Um, Inhwa\|Faratian, Dana\|Zhou, Ying\|Turnbull, Arran K\|Langdon, Simon P\|Harrison, David J
PMID:	26678268

360.
Journal:	Int J Mol Sci. 2015 Dec 29;17(1). pii: ijms17010041.
Title:	Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
Author:	Ren, Bao-Jun\|Zhou, Zhi-Wei\|Zhu, Da-Jian\|Ju, Yong-Le\|Wu, Jin-Hao\|Ouyang, Man-Zhao\|Chen, Xiao-Wu\|Zhou, Shu-Feng
PMID:	26729093

361.
Journal:	Autophagy. 2015;11(12):2309-22.
Title:	Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.
Author:	Wei, Fu-Zheng\|Cao, Ziyang\|Wang, Xi\|Wang, Hui\|Cai, Mu-Yan\|Li, Tingting\|Hattori, Naoko\|Wang, Donglai\|Du, Yipeng\|Song, Boyan\|Cao, Lin-Lin\|Shen, Changchun\|Wang, Lina\|Wang, Haiying\|Yang, Yang\|Xie, Dan\|Wang, Fan\|Ushijima, Toshikazu\|Zhao, Ying\|Zhu, Wei-Guo
PMID:	26735435

362.
Journal:	Oncol Lett. 2015 Dec;10(6):3682-3688.
Title:	Functional mechanism of the enhancement of 5-fluorouracil sensitivity by TUSC4 in colon cancer cells.
Author:	Liu, Ming-Na\|Liu, Ai-Yun\|Pei, Feng-Hua\|Ma, Xiao\|Fan, Yu-Jing\|DU, Ya-Ju\|Liu, Bing-Rong
PMID:	26788191

363.
Journal:	EBioMedicine. 2015 Nov 19;2(12):1944-56.
Title:	PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer.
Author:	Zhang, Yanjie\|Wang, Xiaowen\|Qin, Xiaoyu\|Wang, Xinxin\|Liu, Feng\|White, Eileen\|Zheng, X F Steven
PMID:	26844273

364.
Journal:	Hepatogastroenterology. 2015 Jun;62(140):880-6.
Title:	Rapamycin-Mediated mTOR Inhibition Reverses Drug Resistance to Adriamycin in Colon Cancer Cells.
Author:	Ma, Qiang\|Chang, Zonghong\|Wang, Wei\|Wang, Biaomeng
PMID:	26902021

365.
Journal:	EBioMedicine. 2015 Dec;2(12):1944-1956.
Title:	PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer.
Author:	Zhang, Yanjie\|Wang, Xiaowen\|Qin, Xiaoyu\|Wang, Xinxin\|Liu, Feng\|White, Eileen\|Zheng, X F Steven
PMID:	28958491

366.
Journal:	Environ Toxicol. 2016 Jan;31(1):77-84.
Title:	Hinokitiol induces autophagy in murine breast and colorectal cancer cells.
Author:	Wang, Wei-Kuang\|Lin, Song-Tao\|Chang, Wen-Wei\|Liu, Li-Wen\|Li, Tom Yu-Tung\|Kuo, Chun-Yu\|Hsieh, Jeng-Long\|Lee, Che-Hsin
PMID:	25044443

367.
Journal:	Mol Carcinog. 2016 Feb;55(2):220-9.
Title:	Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.
Author:	Campos, Tania\|Ziehe, Javiera\|Palma, Mario\|Escobar, David\|Tapia, Julio C\|Pincheira, Roxana\|Castro, Ariel F
PMID:	25594310

368.
Journal:	Mol Carcinog. 2016 Mar;55(3):233-44.
Title:	PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition.
Author:	Al-Qasem, Abeer\|Al-Howail, Huda A\|Al-Swailem, Mashael\|Al-Mazrou, Amer\|Al-Otaibi, Basem\|Al-Jammaz, Ibrahim\|Al-Khalaf, Huda H\|Aboussekhra, Abdelilah
PMID:	25641341

369.
Journal:	Eur J Nutr. 2016 Mar;55(2):491-503.
Title:	The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer.
Author:	Hsuan, Shu-Wen\|Chyau, Charng-Cherng\|Hung, Hsiao-Yu\|Chen, Jing-Hsien\|Chou, Fen-Pi
PMID:	25720497

370.
Journal:	Oncogene. 2016 Jan 14;35(2):148-57.
Title:	mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
Author:	He, K\|Zheng, X\|Li, M\|Zhang, L\|Yu, J
PMID:	25867072

371.
Journal:	Gut. 2016 Jul;65(7):1151-64.
Title:	BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.
Author:	Urban, Bettina C\|Collard, Tracey J\|Eagle, Catherine J\|Southern, Samantha L\|Greenhough, Alexander\|Hamdollah-Zadeh, Maryam\|Ghosh, Anil\|Poulsom, Richard\|Paraskeva, Christos\|Silver, Andrew\|Williams, Ann C
PMID:	26033966

372.
Journal:	J Cancer Res Clin Oncol. 2016 Jan;142(1):59-72.
Title:	Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.
Author:	Chang, Ligong\|Wu, Peng\|Senthilkumar, Ravichandran\|Tian, Xiaoqiang\|Liu, Hui\|Shen, Xia\|Tao, Zijian\|Huang, Peilin
PMID:	26109148

373.
Journal:	Gut. 2016 Oct;65(10):1690-701.
Title:	New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Author:	Qi, Jingjing\|Yu, Yong\|Akilli Ozturk, Ozlem\|Holland, Jane D\|Besser, Daniel\|Fritzmann, Johannes\|Wulf-Goldenberg, Annika\|Eckert, Klaus\|Fichtner, Iduna\|Birchmeier, Walter
PMID:	26156959

374.
Journal:	Clin Cancer Res. 2016 Feb 1;22(3):644-56.
Title:	Tankyrase Inhibition Blocks Wnt/beta-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
Author:	Arques, Oriol\|Chicote, Irene\|Puig, Isabel\|Tenbaum, Stephan P\|Argiles, Guillem\|Dienstmann, Rodrigo\|Fernandez, Natalia\|Caratu, Ginevra\|Matito, Judit\|Silberschmidt, Daniel\|Rodon, Jordi\|Landolfi, Stefania\|Prat, Aleix\|Espin, Eloy\|Charco, Ramon\|Nuciforo, Paolo\|
PMID:	26224873

375.
Journal:	Food Chem. 2016 Feb 1;192:142-8.
Title:	Antioxidant and antiproliferative properties of 3-deoxyanthocyanidins.
Author:	Sousa, Andre\|Araujo, Paula\|Azevedo, Joana\|Cruz, Luis\|Fernandes, Iva\|Mateus, Nuno\|de Freitas, Victor
PMID:	26304331

376.
Journal:	In Vitro Cell Dev Biol Anim. 2016 Jan;52(1):45-8.
Title:	Anticancer effect of rapamycin on MCF-7 via downregulation of VEGF expression.
Author:	Fujii, Takaaki\|Yajima, Reina\|Tatsuki, Hironori\|Oosone, Katuya\|Kuwano, Hiroyuki
PMID:	26427711

377.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1516-27.
Title:	Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status.
Author:	Kato, Junko\|Futamura, Manabu\|Kanematsu, Masako\|Gaowa, Siqin\|Mori, Ryutaro\|Tanahashi, Toshiyuki\|Matsuhashi, Nobuhisa\|Yoshida, Kazuhiro
PMID:	26437179

378.
Journal:	Mol Oncol. 2016 Jan;10(1):101-12.
Title:	mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition.
Author:	Massey, Andrew J\|Stephens, Peter\|Rawlinson, Rebecca\|McGurk, Lauren\|Plummer, Ruth\|Curtin, Nicola J
PMID:	26471831

379.
Journal:	Clin Cancer Res. 2016 Mar 15;22(6):1445-58.
Title:	A Novel Bioavailable BH3 Mimetic Efficiently Inhibits Colon Cancer via Cascade Effects of Mitochondria.
Author:	Wang, Xuefeng\|Zhang, Chen\|Yan, Xiangming\|Lan, Bin\|Wang, Jianyong\|Wei, Chongyang\|Cao, Xingxin\|Wang, Renxiao\|Yao, Jianhua\|Zhou, Tao\|Zhou, Mi\|Liu, Qiaoling\|Jiang, Biao\|Jiang, Pengfei\|Kesari, Santosh\|Lin, Xinjian\|Guo, Fang
PMID:	26515494

380.
Journal:	Food Chem Toxicol. 2016 Jan;87:1-11.
Title:	A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells.
Author:	Wani, Zahoor Ahmad\|Guru, Santosh Kumar\|Rao, A V Subba\|Sharma, Sonia\|Mahajan, Girish\|Behl, Akanksha\|Kumar, Ashok\|Sharma, P R\|Kamal, Ahmed\|Bhushan, Shashi\|Mondhe, Dilip M
PMID:	26615871

381.
Journal:	Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6.
Title:	Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.
Author:	Penrose, Harrison\|Heller, Sandra\|Cable, Chloe\|Makboul, Rania\|Chadalawada, Gita\|Chen, Ying\|Crawford, Susan E\|Savkovic, Suzana D
PMID:	26657850

382.
Journal:	Oncol Rep. 2016 Feb;35(2):1091-100.
Title:	Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
Author:	Yousef, Bashir A\|Guerram, Mounia\|Hassan, Hozeifa M\|Hamdi, Aida M\|Zhang, Lu-Yong\|Jiang, Zhen-Zhou
PMID:	26718323

383.
Journal:	Exp Cell Res. 2016 Feb 1;341(1):67-74.
Title:	Arginine starvation in colorectal carcinoma cells: Sensing, impact on translation control and cell cycle distribution.
Author:	Vynnytska-Myronovska, Bozhena O\|Kurlishchuk, Yuliya\|Chen, Oleh\|Bobak, Yaroslav\|Dittfeld, Claudia\|Huther, Melanie\|Kunz-Schughart, Leoni A\|Stasyk, Oleh V
PMID:	26751966

384.
Journal:	Neoplasma. 2016;63(2):193-200.
Title:	Chidamide and 5-flurouracil show a synergistic antitumor effect on human colon cancer xenografts in nude mice.
Author:	Liu, L\|Qiu, S\|Liu, Y\|Liu, Z\|Zheng, Y\|Su, X\|Chen, B\|Chen, H
PMID:	26774139

385.
Journal:	Future Oncol. 2016 Feb;12(4):515-24.
Title:	Effective targeting of colorectal cancer cells using TORC1/2 kinase inhibitors in vitro and in vivo.
Author:	Zhang, Jie\|Jiang, Wen\|Liu, Wei\|Wu, Juan-Juan\|Song, Lei\|Cheng, Ji-Xian\|Yao, Ming\|Yang, Li-Ping\|Yao, Deng-Fu
PMID:	26776341

386.
Journal:	Oncotarget. 2016 Feb 23;7(8):9188-221.
Title:	BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author:	Goulielmaki, Maria\|Koustas, Evangelos\|Moysidou, Eirini\|Vlassi, Margarita\|Sasazuki, Takehiko\|Shirasawa, Senji\|Zografos, George\|Oikonomou, Eftychia\|Pintzas, Alexander
PMID:	26802026

387.
Journal:	Mol Cancer Res. 2016 Apr;14(4):385-96.
Title:	KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Author:	Ghaleb, Amr M\|Elkarim, Enas A\|Bialkowska, Agnieszka B\|Yang, Vincent W
PMID:	26839262

388.
Journal:	Molecules. 2016 Jan 30;21(2):169.
Title:	Chemopreventive and Therapeutic Effects of Edible Berries: A Focus on Colon Cancer Prevention and Treatment.
Author:	Afrin, Sadia\|Giampieri, Francesca\|Gasparrini, Massimiliano\|Forbes-Hernandez, Tamara Y\|Varela-Lopez, Alfonso\|Quiles, Jose L\|Mezzetti, Bruno\|Battino, Maurizio
PMID:	26840292

389.
Journal:	PLoS One. 2016 Feb 10;11(2):e0148730.
Title:	Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.
Author:	Yueh, Alexander E\|Payne, Susan N\|Leystra, Alyssa A\|Van De Hey, Dana R\|Foley, Tyler M\|Pasch, Cheri A\|Clipson, Linda\|Matkowskyj, Kristina A\|Deming, Dustin A
PMID:	26863299

390.
Journal:	Eur J Pharmacol. 2016 Apr 5;776:124-31.
Title:	Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways.
Author:	Lien, Gi-Shih\|Lin, Chien-Huang\|Yang, You-Lan\|Wu, Ming-Shun\|Chen, Bing-Chang
PMID:	26879868

391.
Journal:	Sci Rep. 2016 Feb 19;6:21420.
Title:	Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-kappaB activation.
Author:	Wu, Xiao-Bing\|Liu, Yang\|Wang, Gui-Hua\|Xu, Xiao\|Cai, Yang\|Wang, Hong-Yi\|Li, Yan-Qi\|Meng, Hong-Fang\|Dai, Fu\|Jin, Ji-De
PMID:	26892992

392.
Journal:	Sci Rep. 2016 Feb 26;6:22146.
Title:	In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line.
Author:	Wang, Jigang\|Zhang, Jianbin\|Zhang, Chong-Jing\|Wong, Yin Kwan\|Lim, Teck Kwang\|Hua, Zi-Chun\|Liu, Bin\|Tannenbaum, Steven R\|Shen, Han-Ming\|Lin, Qingsong
PMID:	26915414

393.
Journal:	Oncotarget. 2016 Mar 29;7(13):16349-61.
Title:	AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Author:	Gao, Mei\|Kong, Qingbin\|Hua, Hui\|Yin, Yancun\|Wang, Jiao\|Luo, Ting\|Jiang, Yangfu
PMID:	26918349

394.
Journal:	Phytother Res. 2016 Jun;30(6):963-70.
Title:	Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-alpha-Dependent Inhibition of Akt/mTOR Pathway.
Author:	Sarnelli, Giovanni\|Gigli, Stefano\|Capoccia, Elena\|Iuvone, Teresa\|Cirillo, Carla\|Seguella, Luisa\|Nobile, Nicola\|D'Alessandro, Alessandra\|Pesce, Marcella\|Steardo, Luca\|Cuomo, Rosario\|Esposito, Giuseppe
PMID:	26929026

395.
Journal:	Mol Med Rep. 2016 Apr;13(4):3243-8.
Title:	Silybin suppresses cell proliferation and induces apoptosis of multiple myeloma cells via the PI3K/Akt/mTOR signaling pathway.
Author:	Feng, Nan\|Luo, Jianmin\|Guo, Ximin
PMID:	26936429

396.
Journal:	J Korean Med Sci. 2016 Mar;31(3):360-70.
Title:	Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation.
Author:	Kim, Min-Jung\|Koo, Jeong-Eun\|Han, Gi-Yeon\|Kim, Buyun\|Lee, Yoo-Sun\|Ahn, Chiyoung\|Kim, Chan-Wha
PMID:	26955235

397.
Journal:	Proteomics. 2016 May;16(10):1557-69.
Title:	Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author:	Tai, William Chi-Shing\|Wong, Wing-Yan\|Lee, Magnolia Muk-Lan\|Chan, Brandon Dow\|Lu, Cheng\|Hsiao, Wen-Luan Wendy
PMID:	26970558

398.
Journal:	Tumour Biol. 2016 Sep;37(9):11743-11752.
Title:	Autophagy inhibition sensitizes WYE-354-induced anti-colon cancer activity in vitro and in vivo.
Author:	Wang, Lijun\|Zhu, Yun-Rong\|Wang, Shaowei\|Zhao, Song
PMID:	27020593

399.
Journal:	Mol Nutr Food Res. 2016 Sep;60(9):1912-23.
Title:	Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.
Author:	Kim, Hyemee\|Banerjee, Nivedita\|Ivanov, Ivan\|Pfent, Catherine M\|Prudhomme, Kalan R\|Bisson, William H\|Dashwood, Roderick H\|Talcott, Stephen T\|Mertens-Talcott, Susanne U
PMID:	27028006

400.
Journal:	Genes Chromosomes Cancer. 2016 Jul;55(7):577-90.
Title:	Lentivirus-mediated somatic recombination and development of a novel mouse model for sporadic colorectal cancer.
Author:	Vaish, Vivek\|Kim, Joohwee\|Shim, Minsub
PMID:	27037682

401.
Journal:	Biomed Pharmacother. 2016 Apr;79:112-9.
Title:	Pristimerin inhibits proliferation, migration and invasion, and induces apoptosis in HCT-116 colorectal cancer cells.
Author:	Yousef, Bashir A\|Hassan, Hozeifa M\|Guerram, Mounia\|Hamdi, Aida M\|Wang, Bin\|Zhang, Lu-Yong\|Jiang, Zhen-Zhou
PMID:	27044819

402.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2016 Mar;36(3):396-400.
Title:	[Expression of Rictor and mTOR in colorectal cancer and their clinical significance].
Author:	Wang, Li-Feng\|Chen, Hai-Jin\|Yu, Jin-Long\|Qi, Jia\|Lin, Xiao-Hua\|Zou, Zhao-Wei
PMID:	27063170

403.
Journal:	J Nat Prod. 2016 Apr 22;79(4):1097-104.
Title:	Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
Author:	Kim, Won Kyung\|Pyee, Yuna\|Chung, Hwa-Jin\|Park, Hyen Joo\|Hong, Ji-Young\|Son, Kun Ho\|Lee, Sang Kook
PMID:	27064730

404.
Journal:	PLoS One. 2016 Apr 14;11(4):e0153627.
Title:	Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells.
Author:	Lai, Ming-Chih\|Chang, Chiao-May\|Sun, H Sunny
PMID:	27078027

405.
Journal:	Oncotarget. 2016 May 17;7(20):29216-27.
Title:	Silencing homeobox C6 inhibits colorectal cancer cell proliferation.
Author:	Ji, Meiling\|Feng, Qingyang\|He, Guodong\|Yang, Liangliang\|Tang, Wentao\|Lao, Xinyuan\|Zhu, Dexiang\|Lin, Qi\|Xu, Pingping\|Wei, Ye\|Xu, Jianmin
PMID:	27081081

406.
Journal:	Metabolism. 2016 May;65(5):685-98.
Title:	Aerobic and resistance training dependent skeletal muscle plasticity in the colon-26 murine model of cancer cachexia.
Author:	Khamoui, Andy V\|Park, Bong-Sup\|Kim, Do-Houn\|Yeh, Ming-Chia\|Oh, Seung-Lyul\|Elam, Marcus L\|Jo, Edward\|Arjmandi, Bahram H\|Salazar, Gloria\|Grant, Samuel C\|Contreras, Robert J\|Lee, Won Jun\|Kim, Jeong-Su
PMID:	27085776

407.
Journal:	Sci Rep. 2016 Apr 20;6:24720.
Title:	miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
Author:	El-Daly, Sherien M\|Abba, Mohammed L\|Patil, Nitin\|Allgayer, Heike
PMID:	27095166

408.
Journal:	Carbohydr Polym. 2016 Jul 10;145:30-6.
Title:	Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-kappaB and mTOR signaling.
Author:	Mattaveewong, Tharinee\|Wongkrasant, Preedajit\|Chanchai, Sumalee\|Pichyangkura, Rath\|Chatsudthipong, Varanuj\|Muanprasat, Chatchai
PMID:	27106148

409.
Journal:	Nutrients. 2016 May 2;8(5). pii: nu8050261.
Title:	Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway.
Author:	Tian, Yun\|Wang, Keming\|Fan, Yingrui\|Wang, Yan\|Sun, Liqun\|Wang, Li\|Wang, Jirong\|Wang, Zhaoxia\|Li, Juan\|Ye, Ying\|Ji, Guozhong
PMID:	27144580

410.
Journal:	Am J Transl Res. 2016 Mar 15;8(3):1609-14. eCollection 2016.
Title:	Houttuynia cordata Thunb reverses oxaliplatin-induced neuropathic pain in rat by regulating Th17/Treg balance.
Author:	Wan, Cheng-Fu\|Zheng, Li-Li\|Liu, Yan\|Yu, Xue
PMID:	27186286

411.
Journal:	Mol Cancer Ther. 2016 Jun;15(6):1248-60.
Title:	Inhibition of PI3K/BMX Cell Survival Pathway Sensitizes to BH3 Mimetics in SCLC.
Author:	Potter, Danielle S\|Galvin, Melanie\|Brown, Stewart\|Lallo, Alice\|Hodgkinson, Cassandra L\|Blackhall, Fiona\|Morrow, Christopher J\|Dive, Caroline
PMID:	27197306

412.
Journal:	Int J Oncol. 2016 Jul;49(1):276-84.
Title:	Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma.
Author:	Harada, Koji\|Ferdous, Tarannum\|Harada, Toyoko\|Ueyama, Yoshiya
PMID:	27210058

413.
Journal:	Oncotarget. 2016 Jun 21;7(25):38191-38209.
Title:	Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Author:	Djuzenova, Cholpon S\|Fiedler, Vanessa\|Katzer, Astrid\|Michel, Konstanze\|Deckert, Stefanie\|Zimmermann, Heiko\|Sukhorukov, Vladimir L\|Flentje, Michael
PMID:	27224913

414.
Journal:	Int J Nanomedicine. 2016 May 5;11:1947-58.
Title:	Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis.
Author:	Zou, Hong\|Li, Li\|Garcia Carcedo, Ines\|Xu, Zhi Ping\|Monteiro, Michael\|Gu, Wenyi
PMID:	27226714

415.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2016 Jun 8;45(6):401-6.
Title:	[Roles of glucose-regulated protein 78 in proliferation and migration of human colorectal carcinoma cell line RKO].
Author:	Ji, Q X\|Liu, L L\|Li, L\|Xing, X M
PMID:	27256049

416.
Journal:	Int J Oncol. 2016 Aug;49(2):639-45.
Title:	Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Author:	Esposito, Giuseppe\|Gigli, Stefano\|Seguella, Luisa\|Nobile, Nicola\|D'Alessandro, Alessandra\|Pesce, Marcella\|Capoccia, Elena\|Steardo, Luca\|Cirillo, Carla\|Cuomo, Rosario\|Sarnelli, Giovanni
PMID:	27279570

417.
Journal:	Dev Reprod. 2016 Mar;20(1):1-10.
Title:	Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells.
Author:	Oh, Iljoong\|Cho, Hyunchul\|Lee, Yonghoon\|Cheon, Minseok\|Park, Deokbae\|Lee, Youngki
PMID:	27294206

418.
Journal:	BMC Cancer. 2016 Jun 13;16:366.
Title:	PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
Author:	Kuramochi, Hidekazu\|Nakamura, Ayako\|Nakajima, Go\|Kaneko, Yuka\|Araida, Tatsuo\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	27296289

419.
Journal:	Cancer Biomark. 2016 Jun 7;17(1):1-10.
Title:	Autophagy regulation and its role in gastric cancer and colorectal cancer.
Author:	Zhou, Huangyan\|Yuan, Min\|Yu, Qiongfang\|Zhou, Xiaoyan\|Min, Weiping\|Gao, Dian
PMID:	27314289

420.
Journal:	Oncol Lett. 2016 Jul;12(1):102-106.
Title:	Autophagy inhibition enhances colorectal cancer apoptosis induced by dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
Author:	Yang, Xiaoyu\|Niu, Bingxuan\|Wang, Libo\|Chen, Meiling\|Kang, Xiaochun\|Wang, Luonan\|Ji, Yinghua\|Zhong, Jiateng
PMID:	27347108

421.
Journal:	Oncotarget. 2016 Jul 26;7(30):47699-47710.
Title:	BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells.
Author:	He, Kan\|Chen, Dongshi\|Ruan, Hang\|Li, Xiangyun\|Tong, Jingshan\|Xu, Xiang\|Zhang, Lin\|Yu, Jian
PMID:	27351224

422.
Journal:	Chin J Integr Med. 2016 Jun 29. pii: 10.1007/s11655-016-2597-8.
Title:	Tounong Powder () extracts induce G1 cell cycle arrest and apoptosis in LoVo cells.
Author:	Fang, Liang-Hua\|Liu, Shen-Lin\|Wang, Rui-Ping\|Hu, Shou-You\|Ju, Wen-Zheng\|Li, Chang-Yin
PMID:	27358203

423.
Journal:	Acta Biomater. 2016 Sep 15;42:220-231.
Title:	Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells.
Author:	Sundaramoorthy, Pasupathi\|Ramasamy, Thiruganesh\|Mishra, Siddhartha Kumar\|Jeong, Keun-Yeong\|Yong, Chul Soon\|Kim, Jong Oh\|Kim, Hwan Mook
PMID:	27395829

424.
Journal:	Mol Cancer Res. 2016 Sep;14(9):830-40.
Title:	Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma.
Author:	Li, Qingguo\|Qin, Yi\|Wei, Ping\|Lian, Peng\|Li, Yaqi\|Xu, Ye\|Li, Xinxiang\|Li, Dawei\|Cai, Sanjun
PMID:	27401611

425.
Journal:	Oncol Rep. 2016 Sep;36(3):1526-34.
Title:	A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Author:	Dai, Bingling\|Wang, Wenjie\|Ma, Yujiao\|Liu, Rui\|Zhang, Yanmin
PMID:	27460008

426.
Journal:	BMC Cancer. 2016 Jul 26;16:531.
Title:	Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells.
Author:	Risberg, Karianne\|Redalen, Kathrine Roe\|Sonstevold, Linda\|Bjornetro, Tonje\|Solvernes, Janne\|Ree, Anne Hansen
PMID:	27461218

427.
Journal:	Skelet Muscle. 2016 Jul 26;6:26.
Title:	ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments.
Author:	Hatakeyama, Shinji\|Summermatter, Serge\|Jourdain, Marie\|Melly, Stefan\|Minetti, Giulia C\|Lach-Trifilieff, Estelle
PMID:	27462398

428.
Journal:	Br J Cancer. 2016 Sep 6;115(6):682-90.
Title:	Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.
Author:	Beale, Gary\|Haagensen, Emma J\|Thomas, Huw D\|Wang, Lan-Zhen\|Revill, Charlotte H\|Payne, Sara L\|Golding, Bernard T\|Hardcastle, Ian R\|Newell, David R\|Griffin, Roger J\|Cano, Celine
PMID:	27529512

429.
Journal:	Hered Cancer Clin Pract. 2016 Aug 23;14(1):17.
Title:	Cytotoxic and targeted therapy for hereditary cancers.
Author:	Iyevleva, Aglaya G\|Imyanitov, Evgeny N
PMID:	27555886

430.
Journal:	Oncotarget. 2016 Sep 20;7(38):61509-61519.
Title:	Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells.
Author:	Jing, Zhao\|Fei, Weiqiang\|Zhou, Jichun\|Zhang, Lumin\|Chen, Liuxi\|Zhang, Xiaomin\|Liang, Xiao\|Xie, Jiansheng\|Fang, Yong\|Sui, Xinbing\|Han, Weidong\|Pan, Hongming
PMID:	27557491

431.
Journal:	Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20.
Title:	mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Author:	Jin, Zhe-Zhu\|Wang, Wei\|Fang, Di-Long\|Jin, Yong-Jun
PMID:	27565731

432.
Journal:	PLoS One. 2016 Sep 9;11(9):e0162568.
Title:	A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration.
Author:	Ban, Hyun Seung\|Xu, Xuezhen\|Jang, Kusik\|Kim, Inhyub\|Kim, Bo-Kyung\|Lee, Kyeong\|Won, Misun
PMID:	27611801

433.
Journal:	Oncotarget. 2016 Oct 18;7(42):68749-68767.
Title:	Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
Author:	Moench, Romana\|Grimmig, Tanja\|Kannen, Vinicius\|Tripathi, Sudipta\|Faber, Marc\|Moll, Eva-Maria\|Chandraker, Anil\|Lissner, Reinhard\|Germer, Christoph-Thomas\|Waaga-Gasser, Ana Maria\|Gasser, Martin
PMID:	27626684

434.
Journal:	Oncotarget. 2016 Oct 18;7(42):68328-68338.
Title:	GOLPH3 overexpression correlates with poor response to neoadjuvant therapy and prognosis in locally advanced rectal cancer.
Author:	Zhu, Kunli\|Zhao, Qianqian\|Yue, Jinbo\|Shi, Pengyue\|Yan, Hongjiang\|Xu, Xiaoqing\|Wang, Renben
PMID:	27634904

435.
Journal:	Mol Cancer Res. 2016 Dec;14(12):1204-1216.
Title:	MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling.
Author:	McNew, Kelsey L\|Whipple, William J\|Mehta, Anita K\|Grant, Trevor J\|Ray, Leah\|Kenny, Connor\|Singh, Anurag
PMID:	27655129

436.
Journal:	Autophagy. 2016 Dec;12(12):2498-2499.
Title:	Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer.
Author:	Wang, Kui\|Gao, Wei\|Dou, Qianhui\|Chen, Haining\|Li, Qifu\|Nice, Edouard C\|Huang, Canhua
PMID:	27657889

437.
Journal:	Apoptosis. 2016 Dec;21(12):1398-1407.
Title:	Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
Author:	Liu, Yan\|Bi, Tingting\|Wang, Zheng\|Wu, Guoliang\|Qian, Liqiang\|Gao, Quangen\|Shen, Genhai
PMID:	27671687

438.
Journal:	Oncotarget. 2016 Nov 15;7(46):75659-75671.
Title:	Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
Author:	Zhang, Jianbin\|Wang, Jigang\|Xu, Jian\|Lu, Yuanqiang\|Jiang, Jiukun\|Wang, Liming\|Shen, Han-Ming\|Xia, Dajing
PMID:	27689333

439.
Journal:	J Cancer. 2016 Jul 25;7(12):1632-1644.
Title:	Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer.
Author:	Figueroa-Gonzalez, Gabriela\|Garcia-Castillo, Veronica\|Coronel-Hernandez, Jossimar\|Lopez-Urrutia, Eduardo\|Leon-Cabrera, Sonia\|Arias-Romero, Luis E\|Terrazas, L I\|Rodriguez-Sosa, Miriam\|Campos-Parra, Alma Delia\|Zuniga-Calzada, Eduardo\|Lopez-Camarillo, Cesar\|
PMID:	27698900

440.
Journal:	Oncotarget. 2016 Nov 15;7(46):75685-75697.
Title:	Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy.
Author:	Li, Gen\|Wu, Anqing\|Qi, Dandan\|Cui, Fengmei\|Zeng, Yanan\|Xie, Fang\|Wu, Hongya\|Gu, Yongping\|Chen, Qiu\|Zhang, Xueguang
PMID:	27708223

441.
Journal:	Cell Oncol (Dordr). 2016 Dec;39(6):545-558.
Title:	DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up.
Author:	Bigagli, Elisabetta\|De Filippo, Carlotta\|Castagnini, Cinzia\|Toti, Simona\|Acquadro, Francesco\|Giudici, Francesco\|Fazi, Marilena\|Dolara, Piero\|Messerini, Luca\|Tonelli, Francesco\|Luceri, Cristina
PMID:	27709558

442.
Journal:	Eur J Cancer. 2016 Nov;68:38-50.
Title:	6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells.
Author:	Zhao, Yueliang\|Fan, Daming\|Ru, Beibei\|Cheng, Ka-Wing\|Hu, Shuting\|Zhang, Jiangwen\|Li, Edmund T S\|Wang, Mingfu
PMID:	27710830

443.
Journal:	Oncol Rep. 2016 Dec;36(6):3559-3567.
Title:	Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.
Author:	Fan, Xiang-Jun\|Wang, Yao\|Wang, Lei\|Zhu, Mingyan
PMID:	27748934

444.
Journal:	Neoplasia. 2016 Nov;18(11):654-665.
Title:	Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Author:	Toda, Kosuke\|Kawada, Kenji\|Iwamoto, Masayoshi\|Inamoto, Susumu\|Sasazuki, Takehiko\|Shirasawa, Senji\|Hasegawa, Suguru\|Sakai, Yoshiharu
PMID:	27764698

445.
Journal:	Sci Rep. 2016 Nov 4;6:36544.
Title:	Probing the PI3K/Akt/mTor pathway using (31)P-NMR spectroscopy: routes to glycogen synthase kinase 3.
Author:	Phyu, Su M\|Tseng, Chih-Chung\|Fleming, Ian N\|Smith, Tim A D
PMID:	27811956

446.
Journal:	Oncol Lett. 2016 Nov;12(5):3771-3778.
Title:	Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells.
Author:	Yang, Lin\|Liu, Yanqing\|Wang, Mei\|Qian, Yayun\|Dai, Xiaojun\|Zhu, Yaodong\|Chen, Jue\|Guo, Shiyu\|Hisamitsu, Tadashi
PMID:	27895729

447.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Nov 28;41(11):1128-1136.
Title:	[Inhibitory effect of jianpi-jiedu prescription-contained serum on colorectal cancer SW48 cell proliferation by mTOR-P53-P21 signalling pathway].
Author:	Lin, Fengxia\|Lei, Sanlin\|Ma, Jin'an\|Shi, Li\|Mao, Dan\|Zhang, Shaofan\|Huang, Jianhua\|Liu, Xinyi\|Ding, Dengfeng\|Zhang, Yingjin\|Zhang, Sifang
PMID:	27932756

448.
Journal:	Nature. 2016 Dec 12. pii: nature20597.
Title:	NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
Author:	Karki, Rajendra\|Man, Si Ming\|Malireddi, R K Subbarao\|Kesavardhana, Sannula\|Zhu, Qifan\|Burton, Amanda R\|Sharma, Bhesh Raj\|Qi, Xiaopeng\|Pelletier, Stephane\|Vogel, Peter\|Rosenstiel, Philip\|Kanneganti, Thirumala-Devi
PMID:	27951586

449.
Journal:	Curr Oncol. 2016 Dec;23(6):e571-e575.
Title:	Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author:	Sheffield, B S\|Tessier-Cloutier, B\|Li-Chang, H\|Shen, Y\|Pleasance, E\|Kasaian, K\|Li, Y\|Jones, S J M\|Lim, H J\|Renouf, D J\|Huntsman, D G\|Yip, S\|Laskin, J\|Marra, M\|Schaeffer, D F
PMID:	28050146

450.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Dec 28;41(12):1297-1304.
Title:	[Effect of jianpi-jiedu formula on tumor angiogenesis-relevant genes expression in colorectal cancer].
Author:	Mao, Dan\|Lei, Sanlin\|Ma, Jin'an\|Shi, Li\|Zhang, Shaofan\|Huang, Jianhua\|Liu, Xinyi\|Ding, Dengfeng\|Zhang, Yingjin\|Feng, Lei\|Zhang, Sifang
PMID:	28070042

451.
Journal:	Genes Dev. 2016 Dec 15;30(24):2684-2695.
Title:	Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
Author:	Davoli, Teresa\|Mengwasser, Kristen E\|Duan, Jingjing\|Chen, Ting\|Christensen, Camilla\|Wooten, Eric C\|Anselmo, Anthony N\|Li, Mamie Z\|Wong, Kwok-Kin\|Kahle, Kristopher T\|Elledge, Stephen J
PMID:	28087713

452.
Journal:	Evid Based Complement Alternat Med. 2016;2016:5698685.
Title:	In Vitro Antiproliferative and Antioxidant Effects of Extracts from Rubus caesius Leaves and Their Quality Evaluation.
Author:	Grochowski, Daniel Miroslaw\|Paduch, Roman\|Wiater, Adrian\|Dudek, Adrianna\|Pleszczynska, Malgorzata\|Tomczykowa, Monika\|Granica, Sebastian\|Polak, Paulina\|Tomczyk, Michal
PMID:	28101119

453.
Journal:	Oncotarget. 2017 Jul 25;8(30):48650-48659.
Title:	PTRF suppresses the progression of colorectal cancers.
Author:	Wang, Fengyun\|Zheng, Yongqiu\|Orange, Matthew\|Yang, Chunlin\|Yang, Bin\|Liu, Jiong\|Tan, Tao\|Ma, Xiangxue\|Chen, Tin\|Yin, Xiaolan\|Tang, Xudong\|Zhu, Hua
PMID:	27203393

454.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):104-115.
Title:	BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.
Author:	Barras, David\|Missiaglia, Edoardo\|Wirapati, Pratyaksha\|Sieber, Oliver M\|Jorissen, Robert N\|Love, Chris\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Gibbs, Peter\|Guinney, Justin\|Simon, Iris M\|Roth, Arnaud D\|Bosman, Fred T\|Tejpar, Sabine\|Delorenzi, Maur
PMID:	27354468

455.
Journal:	J Ethnopharmacol. 2017 Apr 18;202:20-27.
Title:	Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells.
Author:	Cao, Zhi-Xing\|Yang, Yu-Ting\|Yu, Si\|Li, Yu-Zhi\|Wang, Wen-Wen\|Huang, Jing\|Xie, Xiao-Fang\|Xiong, Liang\|Lei, Song\|Peng, Cheng
PMID:	27416805

456.
Journal:	Clin Cancer Res. 2017 Jan 15;23(2):399-406.
Title:	PI3K/Akt/mTOR Signaling and Plasma Membrane Proteins Are Implicated in Responsiveness to Adjuvant Dendritic Cell Vaccination for Metastatic Colorectal Cancer.
Author:	Qian, David C\|Xiao, Xiangjun\|Byun, Jinyoung\|Suriawinata, Arief A\|Her, Stephanie C\|Amos, Christopher I\|Barth, Richard J Jr
PMID:	27435399

457.
Journal:	Mol Carcinog. 2017 Mar;56(3):913-922.
Title:	Protective effect of metformin in an aberrant crypt foci model induced by 1,2-dimethylhydrazine: Modulation of oxidative stress and inflammatory process.
Author:	Bordini, Heloiza Paranzini\|Kremer, Jean Lucas\|Fagundes, Tatiane Renata\|Melo, Gabriella Pasqual\|Conchon-Costa, Ivete\|da Silva, Suelen Santos\|Cecchini, Alessandra Lourenco\|Panis, Carolina\|Luiz, Rodrigo Cabral
PMID:	27585117

458.
Journal:	J Cell Mol Med. 2017 Mar;21(3):588-599.
Title:	A proteomics approach to identifying novel protein targets involved in erinacine A-mediated inhibition of colorectal cancer cells' aggressiveness.
Author:	Lee, Ko-Chao\|Kuo, Hsing-Chun\|Shen, Chien-Heng\|Lu, Chien-Chang\|Huang, Wen-Shih\|Hsieh, Meng-Chiao\|Huang, Cheng-Yi\|Kuo, Yi-Hung\|Hsieh, Yung-Yu\|Teng, Chih-Chuan\|Lee, Li-Ya\|Tung, Shui-Yi
PMID:	27709782

459.
Journal:	Mod Pathol. 2017 Jan;30(1):113-122.
Title:	Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis.
Author:	Pai, Reetesh K\|Cheng, Yu-Wei\|Jakubowski, Maureen A\|Shadrach, Bonnie L\|Plesec, Thomas P\|Pai, Rish K
PMID:	27713420

460.
Journal:	J Clin Pathol. 2017 May;70(5):410-416.
Title:	mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression.
Author:	Sticz, Tamas\|Molnar, Anna\|Mark, Agnes\|Hajdu, Melinda\|Nagy, Noemi\|Vegso, Gyula\|Micsik, Tamas\|Kopper, Laszlo\|Sebestyen, Anna
PMID:	27729429

461.
Journal:	Am J Med Genet A. 2017 Jan;173(1):264-267.
Title:	Smith-Kingsmore syndrome: A third family with the MTOR mutation c.5395G>A p.(Glu1799Lys) and evidence for paternal gonadal mosaicism.
Author:	Moosa, Shahida\|Bohrer-Rabel, Helena\|Altmuller, Janine\|Beleggia, Filippo\|Nurnberg, Peter\|Li, Yun\|Yigit, Gokhan\|Wollnik, Bernd
PMID:	27753196

462.
Journal:	Mol Imaging Biol. 2017 Jun;19(3):421-428.
Title:	Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAF(V600E) In Vivo.
Author:	Schulte, Michael L\|Hight, Matthew R\|Ayers, Gregory D\|Liu, Qi\|Shyr, Yu\|Washington, M Kay\|Manning, H Charles
PMID:	27770401

463.
Journal:	Front Biosci (Landmark Ed). 2017 Jan 1;22:248-257.
Title:	Metformin suppresses CRC growth by inducing apoptosis via ADORA1.
Author:	Lan, Bin\|Zhang, Jian\|Zhang, Peng\|Zhang, Weihong\|Yang, Shugang\|Lu, Dong\|Li, Wenqin\|Dai, Qinbao
PMID:	27814614

464.
Journal:	J Nutr Biochem. 2017 Jan;39:126-133.
Title:	Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity.
Author:	Niku, Mikael\|Pajari, Anne-Maria\|Sarantaus, Laura\|Paivarinta, Essi\|Storvik, Markus\|Heiman-Lindh, Anu\|Suokas, Santeri\|Nystrom, Minna\|Mutanen, Marja
PMID:	27833053

465.
Journal:	Nutr Cancer. 2017 Jan;69(1):44-55.
Title:	Koelreuteria Formosana Extract Induces Growth Inhibition and Cell Death in Human Colon Carcinoma Cells via G2/M Arrest and LC3-II Activation-Dependent Autophagy.
Author:	Horng, Chi-Ting\|Wu, Yueh-Jung\|Chen, Pei-Ni\|Chu, Shu-Chen\|Tsai, Chun-Miao\|Hsieh, Yih-Shou
PMID:	27880045

466.
Journal:	Cancer Lett. 2017 Mar 1;388:85-95.
Title:	FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma.
Author:	Wang, F F\|Zhang, X J\|Yan, Y R\|Zhu, X H\|Yu, J\|Ding, Y\|Hu, J L\|Zhou, W J\|Zeng, Z C\|Liao, W T\|Ding, Y Q\|Liang, L
PMID:	27916606

467.
Journal:	Curr Drug Targets. 2017;18(6):734-750.
Title:	Is Metformin a Therapeutic Paradigm for Colorectal Cancer: Insight into the Molecular Pathway?
Author:	Thent, Zar Chi\|Zaidun, Nurul Hannim\|Azmi, Muhammad Fairuz\|Senin, Mu Izuddin\|Haslan, Haszianaliza\|Salehuddin, Ruzain
PMID:	27919208

468.
Journal:	Cell Death Differ. 2017 Mar;24(3):458-468.
Title:	Ketogenesis contributes to intestinal cell differentiation.
Author:	Wang, Qingding\|Zhou, Yuning\|Rychahou, Piotr\|Fan, Teresa W-M\|Lane, Andrew N\|Weiss, Heidi L\|Evers, B Mark
PMID:	27935584

469.
Journal:	Mol Carcinog. 2017 May;56(5):1427-1437.
Title:	alpha-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer.
Author:	Zhan, Panpan\|Zhao, Shihu\|Yan, Hua\|Yin, Chunli\|Xiao, Yi\|Wang, Yunshan\|Ni, Ruoxuan\|Chen, Weiwen\|Wei, Guangwei\|Zhang, Pengju
PMID:	27996156

470.
Journal:	Oncotarget. 2017 Jan 24;8(4):6419-6432.
Title:	Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells.
Author:	Xiong, Li\|Liu, Zhipeng\|Ouyang, Guoqing\|Lin, Liangwu\|Huang, He\|Kang, Hongxiang\|Chen, Wei\|Miao, Xiongying\|Wen, Yu
PMID:	28031534

471.
Journal:	Cancer Sci. 2017 Mar;108(3):390-397.
Title:	Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion.
Author:	Fujino, Yasuteru\|Takeishi, Shunsaku\|Nishida, Kensei\|Okamoto, Koichi\|Muguruma, Naoki\|Kimura, Tetsuo\|Kitamura, Shinji\|Miyamoto, Hiroshi\|Fujimoto, Akiko\|Higashijima, Jun\|Shimada, Mitsuo\|Rokutan, Kazuhito\|Takayama, Tetsuji
PMID:	28032929

472.
Journal:	Nat Rev Immunol. 2017 Feb;17(2):79.
Title:	Tumour immunology: NLRC3 inhibits mTOR in colorectal cancer.
Author:	Leavy, Olive
PMID:	28044056

473.
Journal:	Biomed Pharmacother. 2017 Mar;87:102-109.
Title:	Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway.
Author:	Dai, Bingling\|Ma, Yujiao\|Yang, Tianfeng\|Wang, Wenjie\|Zhang, Yanmin
PMID:	28049091

474.
Journal:	PLoS One. 2017 Jan 6;12(1):e0169439.
Title:	Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis.
Author:	Lu, Min\|Zessin, Amelia S\|Glover, Wayne\|Hsu, David S
PMID:	28060954

475.
Journal:	Curr Pharm Des. 2017;23(13):2002-2008.
Title:	Current Status and Perspectives Regarding the Therapeutic Potential of Targeting EGFR Pathway by Curcumin in Lung Cancer.
Author:	Shafiee, Mojtaba\|Mohamadzade, Elham\|ShahidSales, Soudabeh\|Khakpouri, Samaneh\|Maftouh, Mina\|Parizadeh, Seyed Alireza\|Hasanian, Seyed Mahdi\|Avan, Amir
PMID:	28117012

476.
Journal:	Mol Clin Oncol. 2017 Jan;6(1):75-78.
Title:	Increased serum leptin level in overweight patients with colon carcinoma: A cross-sectional and prospective study.
Author:	Wang, Di\|Gao, Lichen\|Gong, Kuiyu\|Chai, Qin\|Wang, Guihua
PMID:	28123733

477.
Journal:	Cell Commun Signal. 2017 Feb 1;15(1):9.
Title:	Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin.
Author:	Bommer, Ulrich-Axel\|Vine, Kara L\|Puri, Prianka\|Engel, Martin\|Belfiore, Lisa\|Fildes, Karen\|Batterham, Marijka\|Lochhead, Alistair\|Aghmesheh, Morteza
PMID:	28143584

478.
Journal:	Mol Cancer. 2017 Feb 2;16(1):33.
Title:	Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.
Author:	Ahmad, Rehan\|Alam, Maroof\|Hasegawa, Masanori\|Uchida, Yasumitsu\|Al-Obaid, Omar\|Kharbanda, Surender\|Kufe, Donald
PMID:	28153010

479.
Journal:	Oncotarget. 2017 Jul 25;8(30):48534-48544.
Title:	Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine.
Author:	Parasido, Erika Maria\|Silvestri, Alessandra\|Canzonieri, Vincenzo\|Belluco, Claudio\|Diodoro, Maria Grazia\|Milione, Massimo\|Melotti, Flavia\|De Maria, Ruggero\|Liotta, Lance\|Petricoin, Emanuel F\|Pierobon, Mariaelena
PMID:	28159918

480.
Journal:	Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title:	Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author:	Lee, Sung Hak\|Jung, Seung Hyun\|Kim, Tae-Min\|Rhee, Je-Keun\|Park, Hyeon-Chun\|Kim, Min Sung\|Kim, Sung Soo\|An, Chang Hyeok\|Lee, Sug Hyung\|Chung, Yeun-Jun
PMID:	28179590

481.
Journal:	Mol Cancer Res. 2017 Feb 9;15(3):317-327.
Title:	Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.
Author:	Foley, Tyler M\|Payne, Susan N\|Pasch, Cheri A\|Yueh, Alex E\|Van De Hey, Dana R\|Korkos, Demetra P\|Clipson, Linda\|Maher, Molly E\|Matkowskyj, Kristina A\|Newton, Michael A\|Deming, Dustin A
PMID:	28184015

482.
Journal:	Free Radic Biol Med. 2017 May;106:24-37.
Title:	Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author:	Wang, Gangyang\|Zhang, Tao\|Sun, Wei\|Wang, Hongsheng\|Yin, Fei\|Wang, Zhuoying\|Zuo, Dongqing\|Sun, Mengxiong\|Zhou, Zifei\|Lin, Binhui\|Xu, Jing\|Hua, Yingqi\|Li, Haoqing\|Cai, Zhengdong
PMID:	28188923

483.
Journal:	Cell Rep. 2017 Feb 14;18(7):1699-1712.
Title:	The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1alpha Levels and Colorectal Cancer Cell Survival under Hypoxia.
Author:	Di Conza, Giusy\|Trusso Cafarello, Sarah\|Loroch, Stefan\|Mennerich, Daniela\|Deschoemaeker, Sofie\|Di Matteo, Mario\|Ehling, Manuel\|Gevaert, Kris\|Prenen, Hans\|Zahedi, Rene Peiman\|Sickmann, Albert\|Kietzmann, Thomas\|Moretti, Fabiola\|Mazzone, Massimiliano
PMID:	28199842

484.
Journal:	Oncotarget. 2017 Apr 4;8(14):23603-23612.
Title:	The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.
Author:	Zheng, Hua-Chuan\|Liu, Jia-Jie\|Li, Jing\|Wu, Ji-Cheng\|Yang, Lei\|Zhao, Gui-Feng\|Zhao, Xin\|Jiang, Hua-Mao\|Huang, Ke-Qiang\|Li, Zhi-Jie
PMID:	28223542

485.
Journal:	J Hematol Oncol. 2017 Feb 28;10(1):60.
Title:	Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Author:	Huang, Yan-Jiun\|Yang, Ching-Kuo\|Wei, Po-Li\|Huynh, Thanh-Tuan\|Whang-Peng, Jacqueline\|Meng, Tzu-Ching\|Hsiao, Michael\|Tzeng, Yew-Ming\|Wu, Alexander Th\|Yen, Yun
PMID:	28241877

486.
Journal:	Curr Pharm Des. 2017;23(27):3952-3961.
Title:	Angiogenesis and Oxidative Stress in Metastatic Tumor Progression: Pathogenesis and Novel Therapeutic Approach of Colon Cancer.
Author:	Auyeung, Kathy K\|Ko, Joshua K
PMID:	28245762

487.
Journal:	PLoS One. 2017 Mar 8;12(3):e0172491.
Title:	Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.
Author:	Weber, Lea\|Al-Refae, Klaudia\|Ebbert, Juliane\|Jagers, Peter\|Altmuller, Janine\|Becker, Christian\|Hahn, Stephan\|Gisselmann, Gunter\|Hatt, Hanns
PMID:	28273117

488.
Journal:	Cancer Sci. 2017 Jun;108(6):1185-1193.
Title:	Cancer with low cathepsin D levels is susceptible to vacuolar (H(+) )-ATPase inhibition.
Author:	Kitazawa, Satoshi\|Nishizawa, Satoru\|Nakagawa, Hideyuki\|Funata, Masaaki\|Nishimura, Kazuho\|Soga, Tomoyoshi\|Hara, Takahito
PMID:	28317223

489.
Journal:	Cancer Lett. 2017 Jun 28;396:94-102.
Title:	Co-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer.
Author:	Koustas, Evangelos\|Karamouzis, Michalis V\|Mihailidou, Chrysovalantou\|Schizas, Dimitrios\|Papavassiliou, Athanasios G
PMID:	28323034

490.
Journal:	Sci Rep. 2017 Mar 23;7(1):372.
Title:	Apigenin-induced lysosomal degradation of beta-catenin in Wnt/beta-catenin signaling.
Author:	Lin, Chung-Ming\|Chen, Hsin-Han\|Lin, Chun-An\|Wu, Hui-Chung\|Sheu, Jim Jinn-Chyuan\|Chen, Hui-Jye
PMID:	28337019

491.
Journal:	J Ethnopharmacol. 2017 May 5;203:27-38.
Title:	Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1alpha via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
Author:	Mi, Chunliu\|Ma, Juan\|Wang, Ke Si\|Zuo, Hong Xiang\|Wang, Zhe\|Li, Ming Yue\|Piao, Lian Xun\|Xu, Guang Hua\|Li, Xuezheng\|Quan, Zhe Shan\|Jin, Xuejun
PMID:	28341244

492.
Journal:	Int J Biochem Cell Biol. 2017 Jun;87:54-68.
Title:	Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy.
Author:	Lin, Shengchao\|Yang, Liyan\|Shi, Haiyang\|Du, Wenpei\|Qi, Yingxue\|Qiu, Cen\|Liang, Xin\|Shi, Weibin\|Liu, Jianwen
PMID:	28392376

493.
Journal:	Oncotarget. 2017 Mar 14;8(11):18322-18336.
Title:	The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.
Author:	Zheng, Hua-Chuan\|He, Hao-Yu\|Wu, Ji-Cheng\|Li, Jing\|Zhao, Shuang\|Zhao, Gui-Feng\|Jiang, Hua-Mao\|Yu, Xue-Wen\|Li, Zhi-Jie
PMID:	28407690

494.
Journal:	Clin Colorectal Cancer. 2017 Dec;16(4):410-415.e1.
Title:	A Dose-finding and Biomarker Evaluation Phase Ib Study of Everolimus in Association With 5-Fluorouracil and Pelvic Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Cancer (E-LARC Study).
Author:	Gelsomino, Fabio\|Bertolini, Federica\|Luppi, Gabriele\|Spallanzani, Andrea\|Pettorelli, Elisa\|Reggiani Bonetti, Luca\|Meduri, Bruno\|Manco, Gianrocco\|Conte, Pierfranco\|Cascinu, Stefano
PMID:	28410832

495.
Journal:	Oncotarget. 2017 Apr 18;8(16):26142-26153.
Title:	Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells.
Author:	Banerjee, Aditi\|Banerjee, Vivekjyoti\|Czinn, Steven\|Blanchard, Thomas
PMID:	28412728

496.
Journal:	Toxicol Appl Pharmacol. 2017 Jul 1;326:25-33.
Title:	Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy.
Author:	Ji, Shuai\|Tang, Shunan\|Li, Kai\|Li, Ziwei\|Liang, Wenfei\|Qiao, Xue\|Wang, Qi\|Yu, Siwang\|Ye, Min
PMID:	28416456

497.
Journal:	Oncotarget. 2017 Apr 25;8(17):27929-27942.
Title:	Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathway.
Author:	Sun, Longci\|Jiang, Chunhui\|Xu, Chunjie\|Xue, Hanbing\|Zhou, Hong\|Gu, Lei\|Liu, Ye\|Xu, Qing
PMID:	28427191

498.
Journal:	J Diabetes Complications. 2017 Jul;31(7):1228-1236.
Title:	Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?
Author:	Yang, Juhong\|Nishihara, Reiko\|Zhang, Xuehong\|Ogino, Shuji\|Qian, Zhi Rong
PMID:	28465145

499.
Journal:	Oncotarget. 2017 Jul 18;8(29):47619-47631.
Title:	Peiminine inhibits colorectal cancer cell proliferation by inducing apoptosis and autophagy and modulating key metabolic pathways.
Author:	Zheng, Zhi\|Xu, Liting\|Zhang, Shuofeng\|Li, Wuping\|Tou, Fangfang\|He, Qinsi\|Rao, Jun\|Shen, Qiang
PMID:	28496003

500.
Journal:	Br J Cancer. 2017 Jun 27;117(1):136-143.
Title:	Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
Author:	Chakrabarty, Sanjiban\|Varghese, Vinay Koshy\|Sahu, Pranoy\|Jayaram, Pradyumna\|Shivakumar, Bhadravathi M\|Pai, Cannanore Ganesh\|Satyamoorthy, Kapaettu
PMID:	28524162

501.
Journal:	Hum Gene Ther. 2017 Aug;28(8):690-700.
Title:	An Oncolytic Adenovirus Expressing SNORD44 and GAS5 Exhibits Antitumor Effect in Colorectal Cancer Cells.
Author:	Yuan, Sujing\|Wu, Yu\|Wang, Yigang\|Chen, Jianhua\|Chu, Liang
PMID:	28530127

502.
Journal:	Am J Transl Res. 2017 May 15;9(5):2207-2218. eCollection 2017.
Title:	FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma.
Author:	Liu, Jia Yun\|Wu, Xiao Yu\|Wu, Guan Nan\|Liu, Fu-Kun\|Yao, Xue-Quan
PMID:	28559972

503.
Journal:	Am J Cancer Res. 2017 May 1;7(5):1227-1237. eCollection 2017.
Title:	The identification and validation of Trichosstatin A as a potential inhibitor of colon tumorigenesis and colon cancer stem-like cells.
Author:	Huang, Tse-Hung\|Wu, Szu-Yuan\|Huang, Yan-Jiun\|Wei, Po-Li\|Wu, Alexander Th\|Chao, Tsu-Yi
PMID:	28560069

504.
Journal:	Cell Death Dis. 2017 Jun 1;8(6):e2843.
Title:	The novel hypoxia-inducible factor-1alpha inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Author:	Ban, Hyun Seung\|Kim, Bo-Kyung\|Lee, Hongsub\|Kim, Hwan Mook\|Harmalkar, Dipesh\|Nam, Miso\|Park, Song-Kyu\|Lee, Kiho\|Park, Joon-Tae\|Kim, Inhyub\|Lee, Kyeong\|Hwang, Geum-Sook\|Won, Misun
PMID:	28569777

505.
Journal:	PLoS One. 2017 Jun 8;12(6):e0179202.
Title:	Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author:	Mahfouz, Nadine\|Tahtouh, Roula\|Alaaeddine, Nada\|El Hajj, Joelle\|Sarkis, Riad\|Hachem, Ray\|Raad, Issam\|Hilal, George
PMID:	28594907

506.
Journal:	Semin Cancer Biol. 2017 Oct;46:132-137.
Title:	Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor.
Author:	Popolo, Ada\|Pinto, Aldo\|Daglia, Maria\|Nabavi, Seyed Fazel\|Farooqi, Ammad Ahmad\|Rastrelli, Luca
PMID:	28596013

507.
Journal:	Cell Cycle. 2017 Jul 3;16(13):1243-1251.
Title:	NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.
Author:	Karki, Rajendra\|Malireddi, R K Subbarao\|Zhu, Qifan\|Kanneganti, Thirumala-Devi
PMID:	28598238

508.
Journal:	Acta Pharmacol Sin. 2017 Sep;38(9):1305-1316.
Title:	Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells.
Author:	Fang, Li-Mei\|Li, Bin\|Guan, Jun-Jie\|Xu, Hai-Dong\|Shen, Gen-Hai\|Gao, Quan-Gen\|Qin, Zheng-Hong
PMID:	28603284

509.
Journal:	J Cancer. 2017 Apr 9;8(7):1113-1122.
Title:	A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon Cancer.
Author:	Demirkol, Secil\|Gomceli, Ismail\|Isbilen, Murat\|Dayanc, Baris Emre\|Tez, Mesut\|Bostanci, Erdal Birol\|Turhan, Nesrin\|Akoglu, Musa\|Ozyerli, Ezgi\|Durdu, Sevi\|Konu, Ozlen\|Nissan, Aviram\|Gonen, Mithat\|Gure, Ali Osmay
PMID:	28607584

510.
Journal:	Autophagy. 2017 Aug 3;13(8):1404-1419.
Title:	Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death.
Author:	Leng, Zhi Gen\|Lin, Shao Jian\|Wu, Ze Rui\|Guo, Yu Hang\|Cai, Lin\|Shang, Han Bing\|Tang, Hao\|Xue, Ya Jun\|Lou, Mei Qing\|Zhao, Wenxiu\|Le, Wei-Dong\|Zhao, Wei Guo\|Zhang, Xun\|Wu, Zhe Bao
PMID:	28613975

511.
Journal:	Oncotarget. 2017 Jul 18;8(29):47902-47915.
Title:	mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Author:	Mashima, Tetsuo\|Taneda, Yoko\|Jang, Myung-Kyu\|Mizutani, Anna\|Muramatsu, Yukiko\|Yoshida, Haruka\|Sato, Ayana\|Tanaka, Noritaka\|Sugimoto, Yoshikazu\|Seimiya, Hiroyuki
PMID:	28615517

512.
Journal:	Cell Prolif. 2017 Aug;50(4).
Title:	SAV1 represses the development of human colorectal cancer by regulating the Akt-mTOR pathway in a YAP-dependent manner.
Author:	Jiang, Jianwu\|Chang, Wei\|Fu, Yang\|Gao, Yongshun\|Zhao, Chunlin\|Zhang, Xiefu\|Zhang, Shuijun
PMID:	28618450

513.
Journal:	Clin Exp Metastasis. 2017 Jun;34(5):323-332.
Title:	Portal branch ligation does not counteract the inhibiting effect of temsirolimus on extrahepatic colorectal metastatic growth.
Author:	Senger, Sebastian\|Sperling, Jens\|Oberkircher, Barbara\|Schilling, Martin K\|Kollmar, Otto\|Menger, Michael D\|Ziemann, Christian
PMID:	28631253

514.
Journal:	Int J Biol Sci. 2017 Jun 1;13(6):772-781.
Title:	Angiomotin Family Members: Oncogenes or Tumor Suppressors?
Author:	Lv, Meng\|Shen, Yanwei\|Yang, Jiao\|Li, Shuting\|Wang, Biyuan\|Chen, Zheling\|Li, Pan\|Liu, Peijun\|Yang, Jin
PMID:	28656002

515.
Journal:	Am J Cancer Res. 2017 Jun 1;7(6):1238-1251. eCollection 2017.
Title:	Identification of RING-box 2 as a potential target for combating colorectal cancer growth and metastasis.
Author:	Wu, Xiao-Yu\|Fang, Jian\|Wang, Zhao-Jin\|Chen, Che\|Liu, Jia-Yun\|Wu, Guan-Nan\|Yao, Xue-Quan\|Liu, Fu-Kun\|Zhou, Xin
PMID:	28670488

516.
Journal:	Biomed Pharmacother. 2017 Sep;93:510-521.
Title:	Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis.
Author:	Arun, Ashutosh\|Patel, Om P S\|Saini, Deepika\|Yadav, Prem P\|Konwar, Rituraj
PMID:	28675857

517.
Journal:	Biochem Biophys Res Commun. 2017 Sep 2;490(4):1244-1249.
Title:	Feedback autophagy activation as a key resistance factor of Ku-0060648 in colorectal cancer cells.
Author:	Mao, Mintao\|Liu, Yumei\|Gao, Xinhai
PMID:	28676397

518.
Journal:	Chem Biol Interact. 2017 Aug 25;274:58-67.
Title:	Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1alpha signaling.
Author:	Li, Ming Yue\|Mi, Chunliu\|Wang, Ke Si\|Wang, Zhe\|Zuo, Hong Xiang\|Piao, Lian Xun\|Xu, Guang Hua\|Li, Xuezheng\|Ma, Juan\|Jin, Xuejun
PMID:	28684144

519.
Journal:	Int J Mol Sci. 2017 Jul 14;18(7). pii: ijms18071522.
Title:	Pharmacogenomics of Targeted Agents for Personalization of Colorectal Cancer Treatment.
Author:	Bignucolo, Alessia\|De Mattia, Elena\|Cecchin, Erika\|Roncato, Rossana\|Toffoli, Giuseppe
PMID:	28708103

520.
Journal:	Oncol Rep. 2017 Sep;38(3):1637-1644.
Title:	Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
Author:	Li, Siying\|Yang, Guang\|Zhu, Xiaosong\|Cheng, Lin\|Sun, Yueyue\|Zhao, Zhongxi
PMID:	28737825

521.
Journal:	Anticancer Res. 2017 Aug;37(8):4345-4352.
Title:	miR-141 Inhibits Proliferation and Migration of Colorectal Cancer SW480 Cells.
Author:	Long, Zhi H\|Bai, Zhi G\|Song, Jian N\|Zheng, Zhi\|Li, Jun\|Zhang, Jun\|Cai, Jun\|Yao, Hong W\|Wang, Jin\|Yang, Ying C\|Yin, Jie\|Zhang, Zhong T
PMID:	28739727

522.
Journal:	Life Sci. 2017 Sep 15;185:63-72.
Title:	M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway.
Author:	Peng, Ying\|Qiu, Ling\|Xu, Dong\|Zhang, Li\|Yu, Huixin\|Ding, Yuedi\|Deng, Lili\|Lin, Jianguo
PMID:	28751160

523.
Journal:	Oncogene. 2017 Nov 16;36(46):6480-6489.
Title:	Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma.
Author:	Fujishita, T\|Kojima, Y\|Kajino-Sakamoto, R\|Taketo, M M\|Aoki, M
PMID:	28759045

524.
Journal:	Mol Cancer Ther. 2017 Nov;16(11):2340-2350.
Title:	A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Author:	Galban, Stefanie\|Apfelbaum, April A\|Espinoza, Carlos\|Heist, Kevin\|Haley, Henry\|Bedi, Karan\|Ljungman, Mats\|Galban, Craig J\|Luker, Gary D\|Dort, Marcian Van\|Ross, Brian D
PMID:	28775144

525.
Journal:	J Korean Med Sci. 2017 Sep;32(9):1385-1395.
Title:	Sirolimus and Metformin Synergistically Inhibits Colon Cancer In Vitro and In Vivo.
Author:	Mussin, Nadiar\|Oh, Seung Cheol\|Lee, Kwang Woong\|Park, Min Young\|Seo, Sooin\|Yi, Nam Joon\|Kim, Hyeyoung\|Yoon, Kyung Chul\|Ahn, Sung Woo\|Kim, Hyo Sin\|Hong, Suk Kyun\|Oh, Dong Kyu\|Suh, Kyung Suk
PMID:	28776332

526.
Journal:	Food Res Int. 2017 Sep;99(Pt 1):720-729.
Title:	The phytochemical and bioactivity profiles of wild Asparagus albus L. plant.
Author:	Hamdi, Amel\|Jaramillo-Carmona, Sara\|Srairi Beji, Raja\|Tej, Rabeb\|Zaoui, Sonia\|Rodriguez-Arcos, Rocio\|Jimenez-Araujo, Ana\|Kasri, Mounir\|Lachaal, Mokhtar\|Karray Bouraoui, Najoua\|Guillen-Bejarano, Rafael
PMID:	28784537

527.
Journal:	Crit Rev Food Sci Nutr. 2017 Aug 11:1-13.
Title:	Anthocyanins/anthocyanidins and colorectal cancer: What is behind the scenes?
Author:	de Sousa Moraes, Luis Fernando\|Sun, Xiaofei\|Peluzio, Maria do Carmo Gouveia\|Zhu, Mei-Jun
PMID:	28799785

528.
Journal:	World J Gastroenterol. 2017 Jul 28;23(28):5167-5178.
Title:	Fibroblast-derived CXCL12/SDF-1alpha promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer.
Author:	Ma, Jia-Chi\|Sun, Xiao-Wen\|Su, He\|Chen, Quan\|Guo, Tian-Kang\|Li, Yuan\|Chen, Xiao-Chang\|Guo, Jin\|Gong, Zhen-Qiang\|Zhao, Xiao-Dan\|Qi, Jian-Bo
PMID:	28811711

529.
Journal:	J Cancer. 2017 Jul 15;8(12):2163-2172.
Title:	CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer.
Author:	Wu, Wei\|Wu, Fan\|Wang, Zaozao\|Di, Jiabo\|Yang, Jie\|Gao, Pin\|Jiang, Beihai\|Su, Xiangqian
PMID:	28819418

530.
Journal:	Anal Chem. 2017 Oct 3;89(19):10592-10600.
Title:	Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors.
Author:	Popp, Robert\|Li, Huiyan\|LeBlanc, Andre\|Mohammed, Yassene\|Aguilar-Mahecha, Adriana\|Chambers, Andrew G\|Lan, Cathy\|Poetz, Oliver\|Basik, Mark\|Batist, Gerald\|Borchers, Christoph H
PMID:	28853539

531.
Journal:	PLoS One. 2017 Aug 30;12(8):e0183828.
Title:	miR-625-3p is upregulated in CD8+ T cells during early immune reconstitution after allogeneic stem cell transplantation.
Author:	Verma, Kriti\|Jyotsana, Nidhi\|Buenting, Ivonne\|Luther, Susanne\|Pfanne, Angelika\|Thum, Thomas\|Ganser, Arnold\|Heuser, Michael\|Weissinger, Eva M\|Hambach, Lothar
PMID:	28854245

532.
Journal:	Oncotarget. 2016 Jun 8;8(31):50476-50488.
Title:	Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis.
Author:	Chen, Sugong\|Fisher, Robert C\|Signs, Steven\|Molina, L Alex\|Shenoy, Anitha K\|Lopez, Maria-Cecilia\|Baker, Henry V\|Koomen, John M\|Chen, Yi\|Gittleman, Haley\|Barnholtz-Sloan, Jill\|Berg, Annamarie\|Appelman, Henry D\|Huang, Emina H
PMID:	28881576

533.
Journal:	Oncotarget. 2017 Apr 18;8(32):52783-52791.
Title:	Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells.
Author:	Huang, Yong-Hao\|Sun, Yan\|Huang, Feng-Ying\|Li, Yue-Nan\|Wang, Cai-Chun\|Mei, Wen-Li\|Dai, Hao-Fu\|Tan, Guang-Hong\|Huang, Canhua
PMID:	28881770

534.
Journal:	Cancer Discov. 2017 Nov;7(11):1266-1283.
Title:	A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.
Author:	Rebecca, Vito W\|Nicastri, Michael C\|McLaughlin, Noel\|Fennelly, Colin\|McAfee, Quentin\|Ronghe, Amruta\|Nofal, Michel\|Lim, Chun-Yan\|Witze, Eric\|Chude, Cynthia I\|Zhang, Gao\|Alicea, Gretchen M\|Piao, Shengfu\|Murugan, Sengottuvelan\|Ojha, Rani\|Levi, Samuel M\|Wei,
PMID:	28899863

535.
Journal:	Sci Rep. 2017 Sep 14;7(1):11633.
Title:	Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells.
Author:	Athamneh, Khawlah\|Hasasna, Hussain El\|Samri, Halima Al\|Attoub, Samir\|Arafat, Kholoud\|Benhalilou, Nehla\|Rashedi, Asma Al\|Dhaheri, Yusra Al\|AbuQamar, Synan\|Eid, Ali\|Iratni, Rabah
PMID:	28912474

536.
Journal:	Exp Cell Res. 2017 Nov 15;360(2):328-336.
Title:	miR-338-3p confers 5-fluorouracil resistance in p53 mutant colon cancer cells by targeting the mammalian target of rapamycin.
Author:	Han, Jia\|Li, Jie\|Tang, Kaijie\|Zhang, Huahua\|Guo, Bo\|Hou, Ni\|Huang, Chen
PMID:	28928082

537.
Journal:	J Cancer. 2017 Aug 22;8(14):2713-2719.
Title:	The Impact of Cetuximab Plus AKT- or mTOR- Inhibitor in a Patient-Derived Colon Cancer Cell Model with Wild-Type RAS and PIK3CA Mutation.
Author:	Kim, Ju Sun\|Kim, Jung Eun\|Kim, Kyung\|Lee, Jeeyun\|Park, Joon Oh\|Lim, Ho Yeong\|Park, Young Suk\|Kang, Won Ki\|Kim, Seung Tae
PMID:	28928860

538.
Journal:	Cell Oncol (Dordr). 2017 Dec;40(6):593-607.
Title:	TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
Author:	Das, Sarita\|Nayak, Anmada\|Siddharth, Sumit\|Nayak, Deepika\|Narayan, Satya\|Kundu, Chanakya Nath
PMID:	28936683

539.
Journal:	Ann Surg Oncol. 2017 Dec;24(13):4051-4058.
Title:	Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.
Author:	Clarke, Callisia N\|Lee, Michael S\|Wei, Wei\|Manyam, Ganiraju\|Jiang, Zhi-Qin\|Lu, Yiling\|Morris, Jeffrey\|Broom, Bradley\|Menter, David\|Vilar-Sanchez, Eduardo\|Raghav, Kanwal\|Eng, Cathy\|Chang, George J\|Simon, Iris\|Bernards, Rene\|Overman, Michael\|Mills, Gordon B
PMID:	28936799

540.
Journal:	Mol Med Rep. 2017 Nov;16(5):7864-7872.
Title:	MicroRNA212 inhibits colorectal cancer cell viability and invasion by directly targeting PIK3R3.
Author:	Zhang, Jian\|Zhang, Yongkang\|Li, Xiaoyun\|Wang, Hongbo\|Li, Quan\|Liao, Xiaofeng
PMID:	28944887

541.
Journal:	Sci Rep. 2017 Sep 29;7(1):12406.
Title:	Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells.
Author:	Wu, Tung-Yun\|Cho, Ting-Yu\|Lu, Chung-Kuang\|Liou, Jing-Ping\|Chen, Mei-Chuan
PMID:	28963527

542.
Journal:	Molecules. 2017 Oct 3;22(10). pii: molecules22101657.
Title:	Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.
Author:	Kapral, Malgorzata\|Wawszczyk, Joanna\|Jesse, Katarzyna\|Paul-Samojedny, Monika\|Kusmierz, Dariusz\|Weglarz, Ludmila
PMID:	28972559

543.
Journal:	Cancer Sci. 2017 Dec;108(12):2373-2382.
Title:	Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line.
Author:	Ishimura, Emi\|Nakagawa, Takatoshi\|Moriwaki, Kazumasa\|Hirano, Seiichi\|Matsumori, Yoshinobu\|Asahi, Michio
PMID:	28973823

544.
Journal:	Oncotarget. 2017 Aug 7;8(40):68305-68316.
Title:	Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer.
Author:	Belli, Valentina\|Sforza, Vincenzo\|Cardone, Claudia\|Martinelli, Erika\|Barra, Giusi\|Matrone, Nunzia\|Napolitano, Stefania\|Morgillo, Floriana\|Tuccillo, Concetta\|Federico, Alessandro\|Dallio, Marcello\|Loguercio, Carmelina\|Gravina, Antonietta Gerarda\|De Palma, R
PMID:	28978118

545.
Journal:	Onco Targets Ther. 2017 Sep 11;10:4413-4422.
Title:	Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer.
Author:	Yang, Fei\|Gao, Jun-Yi\|Chen, Hua\|Du, Zhen-Hua\|Zhang, Xue-Qun\|Gao, Wei
PMID:	28979133

546.
Journal:	Cell Death Dis. 2017 Oct 5;8(10):e3087.
Title:	Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells.
Author:	Wang, Sen\|Wang, Kexin\|Zhang, Chundong\|Zhang, Wanfeng\|Xu, Qian\|Wang, Yitao\|Zhang, Yulin\|Li, Yi\|Zhang, Ying\|Zhu, Huifang\|Song, Fangzhou\|Lei, Yunlong\|Bu, Youquan
PMID:	28981110

547.
Journal:	Cancer Lett. 2017 Dec 28;411:57-63.
Title:	Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells.
Author:	Shukla, Kirtikar\|Sonowal, Himangshu\|Saxena, Ashish\|Ramana, Kota V\|Srivastava, Satish K
PMID:	28986187

548.
Journal:	Biomed Pharmacother. 2017 Dec;96:634-641.
Title:	MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer.
Author:	Xu, Song\|Ge, Jingping\|Zhang, Zhengyu\|Zhou, Wenquan
PMID:	29035829

549.
Journal:	Cancer Biomark. 2017 Dec 12;21(1):123-133.
Title:	Knockdown of lncRNA CCAT2 inhibits endometrial cancer cells growth and metastasis via sponging miR-216b.
Author:	Xie, Pengmu\|Cao, Hongying\|Li, Ying\|Wang, Jianhua\|Cui, Zhumei
PMID:	29036788

550.
Journal:	Sci Rep. 2017 Oct 24;7(1):13912.
Title:	Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author:	Dai, Lianzhi\|Chen, Xiaolei\|Lu, Xiaohong\|Wang, Fen\|Zhan, Yanyan\|Song, Gang\|Hu, Tianhui\|Xia, Chun\|Zhang, Bing
PMID:	29066806

551.
Journal:	Target Oncol. 2017 Dec;12(6):775-785.
Title:	A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer.
Author:	Wainberg, Zev A\|Alsina, Maria\|Soares, Heloisa P\|Brana, Irene\|Britten, Carolyn D\|Del Conte, Gianluca\|Ezeh, Patrick\|Houk, Brett\|Kern, Kenneth A\|Leong, Stephen\|Pathan, Nuzhat\|Pierce, Kristen J\|Siu, Lillian L\|Vermette, Jennifer\|Tabernero, Josep
PMID:	29067643

552.
Journal:	Iran J Basic Med Sci. 2017 Sep;20(9):990-995.
Title:	Apatinib has anti-tumor effects and induces autophagy in colon cancer cells.
Author:	Lu, Wu\|Ke, He\|Qianshan, Ding\|Zhen, Wang\|Guoan, Xiang\|Honggang, Yu
PMID:	29085592

553.
Journal:	Obesity (Silver Spring). 2017 Nov;25 Suppl 2:S95-S101.
Title:	The Impact of Diet-Induced Weight Loss on Biomarkers for Colorectal Cancer: An Exploratory Study (INTERCEPT).
Author:	Beeken, Rebecca J\|Croker, Helen\|Heinrich, Malgorzata\|Obichere, Austin\|Finer, Nicholas\|Murphy, Neil\|Goldin, Robert\|Guppy, Naomi J\|Wilson, Rose\|Fisher, Abigail\|Steptoe, Andrew\|Gunter, Marc J\|Wardle, Jane
PMID:	29086510

554.
Journal:	Pathol Oncol Res. 2017 Nov 4. pii: 10.1007/s12253-017-0347-7.
Title:	Invitro Evaluation of Torin2 and 2, 6-Dihydroxyacetophenone in Colorectal Cancer Therapy.
Author:	Awasthi, Ankita\|Kumar, Pharvendra\|Srikanth, Chittur V\|Sahi, Shakti\|Puria, Rekha
PMID:	29103204

555.
Journal:	J BUON. 2017 Sep-Oct;22(5):1107-1114.
Title:	Gene expression profiling demonstrates WNT/beta-catenin pathway genes alteration in Mexican patients with colorectal cancer and diabetes mellitus.
Author:	Ivonne Wence-Chavez, Laura\|Palomares-Chacon, Ulises\|Pablo Flores-Gutierrez, Juan\|Felipe Jave-Suarez, Luis\|Del Carmen Aguilar-Lemarroy, Adriana\|Barros-Nunez, Patricio\|Esperanza Flores-Martinez, Silvia\|Sanchez-Corona, Jose\|Alejandra Rosales-Reynoso, Monica
PMID:	29135090

556.
Journal:	Oncotarget. 2017 Sep 28;8(48):84426-84433.
Title:	Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN.
Author:	Laes, Jean-Francois\|Sauvage, Sebastien\|Ghitti, Gregori
PMID:	29137436

557.
Journal:	Oncotarget. 2017 Aug 9;8(49):84685-84696.
Title:	Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Author:	Cameron, Angus J M\|Veeriah, Selvaraju\|Marshall, Jacqueline J T\|Murray, Elizabeth R\|Larijani, Banafshe\|Parker, Peter J
PMID:	29156676

558.
Journal:	Sci Rep. 2017 Nov 22;7(1):15992.
Title:	Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production.
Author:	Mogavero, Angela\|Maiorana, Maria Valeria\|Zanutto, Susanna\|Varinelli, Luca\|Bozzi, Fabio\|Belfiore, Antonino\|Volpi, Chiara C\|Gloghini, Annunziata\|Pierotti, Marco A\|Gariboldi, Manuela
PMID:	29167573

559.
Journal:	Oncotarget. 2017 Aug 3;8(51):88563-88574.
Title:	Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death.
Author:	Chen, Shun-Ting\|Lee, Tzung-Yan\|Tsai, Tung-Hu\|Huang, Yu-Chuen\|Lin, Yin-Cheng\|Lin, Chin-Ping\|Shieh, Hui-Ru\|Hsu, Ming-Ling\|Chi, Chih-Wen\|Lee, Ming-Cheng\|Chang, Hen-Hong\|Chen, Yu-Jen
PMID:	29179457

560.
Journal:	Biomed Pharmacother. 2017 Dec;96:974-981.
Title:	miRNA-495 suppresses proliferation and migration of colorectal cancer cells by targeting FAM83D.
Author:	Yan, Likun\|Yao, Jianfeng\|Qiu, Jian
PMID:	29221726

561.
Journal:	BMC Complement Altern Med. 2017 Dec 16;17(1):538.
Title:	Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer.
Author:	Li, Hai\|Chen, Chen
PMID:	29246220

562.
Journal:	Oncotarget. 2017 Sep 5;8(60):101224-101243.
Title:	Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Author:	Golob-Schwarzl, Nicole\|Schweiger, Caroline\|Koller, Carina\|Krassnig, Stefanie\|Gogg-Kamerer, Margit\|Gantenbein, Nadine\|Toeglhofer, Anna M\|Wodlej, Christina\|Bergler, Helmut\|Pertschy, Brigitte\|Uranitsch, Stefan\|Holter, Magdalena\|El-Heliebi, Amin\|Fuchs, Julia\|
PMID:	29254159

563.
Journal:	Oncotarget. 2017 Nov 1;8(61):104347-104358.
Title:	Therapeutic effects of the euglenoid ichthyotoxin, euglenophycin, in colon cancer.
Author:	Cabang, April B\|De Mukhopadhyay, Keya\|Meyers, Sarah\|Morris, Jay\|Zimba, Paul V\|Wargovich, Michael J
PMID:	29262645

564.
Journal:	J Exp Clin Cancer Res. 2017 Dec 22;36(1):190.
Title:	Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice.
Author:	Zhang, Pan\|Lai, Ze-Lin\|Chen, Hui-Fen\|Zhang, Min\|Wang, An\|Jia, Tao\|Sun, Wen-Qin\|Zhu, Xi-Min\|Chen, Xiao-Feng\|Zhao, Zheng\|Zhang, Jun
PMID:	29273065

565.
Journal:	Oncol Lett. 2017 Dec;14(6):7410-7416.
Title:	L-type amino acid transporter 1 expression is upregulated and associated with cellular proliferation in colorectal cancer.
Author:	Hayase, Suguru\|Kumamoto, Kensuke\|Saito, Katsuharu\|Kofunato, Yasuhide\|Sato, Yu\|Okayama, Hirokazu\|Miyamoto, Kotaro\|Ohki, Shinji\|Takenoshita, Seiichi
PMID:	29344181

566.
Journal:	J Cell Biochem. 2018 Mar;119(3):2460-2469.
Title:	Therapeutic Potential of Targeting PI3K/AKT Pathway in Treatment of Colorectal Cancer: Rational and Progress.
Author:	Bahrami, Afsane\|Khazaei, Majid\|Hasanzadeh, Malihe\|ShahidSales, Soodabeh\|Joudi Mashhad, Mona\|Farazestanian, Marjaneh\|Sadeghnia, Hamid Reza\|Rezayi, Majid\|Maftouh, Mina\|Hassanian, Seyed Mahdi\|Avan, Amir
PMID:	28230287

567.
Journal:	J Cell Physiol. 2018 Jan;233(1):497-505.
Title:	Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC.
Author:	Won, Shen-Jeu\|Yen, Cheng-Hsin\|Lin, Ting-Yu\|Jiang-Shieh, Ya-Fen\|Lin, Chun-Nan\|Chen, Jyun-Ti\|Su, Chun-Li
PMID:	28294332

568.
Journal:	Nat Prod Res. 2018 Jun;32(12):1489-1492.
Title:	Anticancer effect of Polyphyllin Iota in colorectal cancer cells through ROS-dependent autophagy and G2/M arrest mechanisms.
Author:	Yu, Si\|Wang, Lijiao\|Cao, Zhixing\|Gong, Daoyin\|Liang, Qianyi\|Chen, Hanting\|Fu, Huizhu\|Wang, Wenwen\|Tang, Xue\|Xie, Zihao\|He, Yang\|Peng, Cheng\|Li, Yuzhi
PMID:	28714320

569.
Journal:	Endocr Pathol. 2018 Mar;29(1):21-26.
Title:	Expanding the Spectrum of Colonic Manifestations in Tuberous Sclerosis: L-Cell Neuroendocrine Tumor Arising in the Background of Rectal PEComa.
Author:	Kolin, David L\|Duan, Kai\|Ngan, Bo\|Gerstle, J Ted\|Krzyzanowska, Monika K\|Somers, Gino R\|Mete, Ozgur
PMID:	28733877

570.
Journal:	Asian J Surg. 2018 Sep;41(5):480-485.
Title:	Clinical manifestations and STK11 germline mutations in Taiwanese patients with Peutz-Jeghers syndrome.
Author:	Chiang, Jy-Ming\|Chen, Tse-Ching
PMID:	28869103

571.
Journal:	J Cell Biochem. 2018 Feb;119(2):2356-2367.
Title:	Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-beta/PI3K-AKT-mTOR signaling pathway.
Author:	Wu, Xue-Liang\|Wang, Li-Kun\|Yang, Dong-Dong\|Qu, Ming\|Yang, Yong-Jiang\|Guo, Fei\|Han, Lei\|Xue, Jun
PMID:	28884839

572.
Journal:	J Recept Signal Transduct Res. 2018 Feb;38(1):1-11.
Title:	Identifying novel small molecule antagonists for mLST8 protein using computational approaches.
Author:	Sapam, Tuleshwori Devi\|Velmurugan Ilavarasi, Anbumani\|Palaka, Bhagath Kumar\|Elumalai, Elakkiya\|Kanika, Nirmala Devi\|Ampasala, Dinakara Rao
PMID:	29041842

573.
Journal:	Biochem Biophys Res Commun. 2018 Jan 1;495(1):539-545.
Title:	Long non-coding RNA-422 acts as a tumor suppressor in colorectal cancer.
Author:	Shao, Qianwen\|Xu, Jing\|Deng, Rong\|Wei, Wei\|Zhou, Bing\|Yue, Chao\|Zhu, Miaoling\|Huang, Xingen\|Zhu, Haitao
PMID:	29050940

574.
Journal:	Exp Cell Res. 2018 Jan 1;362(1):63-71.
Title:	Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human gammadeltaT cells against colon cancer.
Author:	Chen, Yong-Qiang\|Zheng, Lu\|Aldarouish, Mohanad\|Zhou, Zhong-Hai\|Pan, Ning\|Liu, Jun-Quan\|Chen, Fu-Xing\|Wang, Li-Xin
PMID:	29104081

575.
Journal:	Pharmacol Rev. 2018 Jan;70(1):1-11.
Title:	RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.
Author:	Yan, Chao\|Theodorescu, Dan
PMID:	29196555

576.
Journal:	Oncol Rep. 2018 Feb;39(2):633-642.
Title:	MicroRNA-411 inhibits malignant biological behaviours of colorectal cancer cells by directly targeting PIK3R3.
Author:	Zhao, Jian\|Xu, Jian\|Zhang, Rui
PMID:	29207180

577.
Journal:	Cancer Res. 2018 Feb 1;78(3):659-670.
Title:	Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.
Author:	Tommelein, Joke\|De Vlieghere, Elly\|Verset, Laurine\|Melsens, Elodie\|Leenders, Justine\|Descamps, Benedicte\|Debucquoy, Annelies\|Vanhove, Christian\|Pauwels, Patrick\|Gespach, Christian P\|Vral, Anne\|De Boeck, Astrid\|Haustermans, Karin\|de Tullio, Pascal\|Ceelen,
PMID:	29217764

578.
Journal:	Mol Cancer Res. 2018 Mar;16(3):543-553.
Title:	TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting beta-CATENIN and AKT Signaling in Colorectal Cancer.
Author:	Solberg, Nina T\|Waaler, Jo\|Lund, Kaja\|Mygland, Line\|Olsen, Petter A\|Krauss, Stefan
PMID:	29222171

579.
Journal:	J Cell Biochem. 2018 Apr;119(4):3763-3774.
Title:	Hyperthermia enhances radiosensitivity of colorectal cancer cells through ROS inducing autophagic cell death.
Author:	Ba, Ming-Chen\|Long, Hui\|Wang, Shuai\|Wu, Yin-Bing\|Zhang, Bo-Huo\|Yan, Zhao-Fei\|Yu, Fei-Hong\|Cui, Shu-Zhong
PMID:	29240246

580.
Journal:	Mol Cancer Ther. 2018 Jan;17(1):3-16.
Title:	Rational Approaches for Combination Therapy Strategies Targeting the MAP Kinase Pathway in Solid Tumors.
Author:	Tolcher, Anthony W\|Peng, Wei\|Calvo, Emiliano
PMID:	29295962

581.
Journal:	Biochem Biophys Res Commun. 2018 Jan 29;496(1):159-166.
Title:	Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation.
Author:	Kim, Jaewhan\|Choi, Sunkyung\|Kim, Jong Ok\|Kim, Kee K
PMID:	29307823

582.
Journal:	Mol Med Rep. 2018 Mar;17(3):4619-4626.
Title:	miR1273g3p promotes proliferation, migration and invasion of LoVo cells via cannabinoid receptor 1 through activation of ERBB4/PIK3R3/mTOR/S6K2 signaling pathway.
Author:	Li, Min\|Qian, Xiaoping\|Zhu, Mingzhen\|Li, Aiyi\|Fang, Mingzhi\|Zhu, Yong\|Zhang, Jingyu
PMID:	29328379

583.
Journal:	Cancer. 2018 Apr 1;124(7):1358-1373.
Title:	Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Author:	Ross, Jeffrey S\|Fakih, Marwan\|Ali, Siraj M\|Elvin, Julia A\|Schrock, Alexa B\|Suh, James\|Vergilio, Jo-Anne\|Ramkissoon, Shakti\|Severson, Eric\|Daniel, Sugganth\|Fabrizio, David\|Frampton, Garrett\|Sun, James\|Miller, Vincent A\|Stephens, Philip J\|Gay, Laurie M
PMID:	29338072

584.
Journal:	Mol Med Rep. 2018 Mar;17(3):4203-4212.
Title:	Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway.
Author:	You, Shuping\|Li, Weihong\|Guan, Yun
PMID:	29344654

585.
Journal:	Biochem Biophys Res Commun. 2018 Mar 25;498(1):246-253.
Title:	Ginkgolic acid induces interplay between apoptosis and autophagy regulated by ROS generation in colon cancer.
Author:	Liu, Yuxia\|Yang, Bin\|Zhang, Lirong\|Cong, Xianling\|Liu, Zhen\|Hu, Yu\|Zhang, Jing\|Hu, Haixia
PMID:	29353042

586.
Journal:	Biomed Pharmacother. 2018 Mar;99:402-410.
Title:	NF-kappaB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling.
Author:	Bai, Fei\|Zhou, Huijun\|Fu, Zhongping\|Xie, Jiangbo\|Hu, Yingbin\|Nie, Shaolin
PMID:	29367109

587.
Journal:	Oncol Res. 2018 Sep 14;26(8):1295-1305.
Title:	MicroRNA-204 Inhibits the Growth and Motility of Colorectal Cancer Cells by Downregulation of CXCL8.
Author:	Shuai, Feng\|Wang, Bo\|Dong, Shuxiao
PMID:	29402343

588.
Journal:	Eur J Cancer. 2018 Mar;92:1-10.
Title:	Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.
Author:	Verlingue, Loic\|Hollebecque, Antoine\|Lacroix, Ludovic\|Postel-Vinay, Sophie\|Varga, Andrea\|El Dakdouki, Yolla\|Baldini, Capucine\|Balheda, Rastilav\|Gazzah, Anas\|Michot, Jean-Marie\|Marabelle, Aurelien\|Mir, Olivier\|Arnedos, Monica\|Rouleau, Etienne\|Solary, Eric\|
PMID:	29413684

589.
Journal:	Oncol Lett. 2018 Feb;15(2):2085-2090.
Title:	Fyn knockdown inhibits migration and invasion in cholangiocarcinoma through the activated AMPK/mTOR signaling pathway.
Author:	Lyu, Shao-Cheng\|Han, Dong-Dong\|Li, Xian-Liang\|Ma, Jun\|Wu, Qiao\|Dong, Hong-Meng\|Bai, Chun\|He, Qiang
PMID:	29434909

590.
Journal:	Oncol Lett. 2018 Mar;15(3):3127-3132.
Title:	Effect of silencing colon cancer-associated transcript 2 on the proliferation, apoptosis and autophagy of gastric cancer BGC-823 cells.
Author:	Yu, Zhao-Yan\|Wang, Zi\|Lee, Ke-Yue\|Yuan, Ping\|Ding, Jie
PMID:	29435046

591.
Journal:	Endocr Relat Cancer. 2018 Apr;25(4):471-480.
Title:	Ex vivo activity of cytotoxic drugs and targeted agents in small intestinal neuroendocrine tumors.
Author:	Daskalakis, Kosmas\|Norlen, Olov\|Karakatsanis, Andreas\|Hellman, Per\|Larsson, Rolf\|Nygren, Peter\|Stalberg, Peter
PMID:	29440231

592.
Journal:	Mol Carcinog. 2018 Jun;57(6):700-721.
Title:	Deciphering the biochemical and molecular mechanism underlying the in vitro and in vivo chemotherapeutic efficacy of ruthenium quercetin complex in colon cancer.
Author:	Roy, Souvik\|Das, Rituparna\|Ghosh, Balaram\|Chakraborty, Tania
PMID:	29442390

593.
Journal:	Neoplasia. 2018 Mar;20(3):244-255.
Title:	Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling.
Author:	Matthew, Elizabeth M\|Yang, Zhaohai\|Peri, Suraj\|Andrake, Mark\|Dunbrack, Roland\|Ross, Eric\|El-Deiry, Wafik S
PMID:	29448085

594.
Journal:	Anticancer Res. 2018 Mar;38(3):1445-1454.
Title:	AZD8055 Exerts Antitumor Effects on Colon Cancer Cells by Inhibiting mTOR and Cell-cycle Progression.
Author:	Chen, Yun\|Lee, Cheng-Hung\|Tseng, Bor-Yuan\|Tsai, Ya-Hui\|Tsai, Huang-Wen\|Yao, Chao-Ling\|Tseng, Sheng-Hong
PMID:	29491070

595.
Journal:	Genes (Basel). 2018 Mar 1;9(3). pii: genes9030133.
Title:	Functional Anthocyanin-Rich Sausages Diminish Colorectal Cancer in an Animal Model and Reduce Pro-Inflammatory Bacteria in the Intestinal Microbiota.
Author:	Fernandez, Javier\|Garcia, Lorena\|Monte, Joaquin\|Villar, Claudio J\|Lombo, Felipe
PMID:	29494510

596.
Journal:	Bull Cancer. 2018 Apr;105(4):336-349.
Title:	Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway.
Author:	Dai, Guangyao\|Yao, Xiaoguang\|Zhang, Yubin\|Gu, Jianbin\|Geng, Yunfeng\|Xue, Fei\|Zhang, Jingcheng
PMID:	29496262

597.
Journal:	Genomics Proteomics Bioinformatics. 2018 Feb;16(1):73-84.
Title:	The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling.
Author:	Luna Coronell, Johana A\|Sergelen, Khulan\|Hofer, Philipp\|Gyurjan, Istvan\|Brezina, Stefanie\|Hettegger, Peter\|Leeb, Gernot\|Mach, Karl\|Gsur, Andrea\|Weinhausel, Andreas
PMID:	29505855

598.
Journal:	J Bioenerg Biomembr. 2018 Jun;50(3):213-222.
Title:	Cross regulation between mTOR signaling and O-GlcNAcylation.
Author:	Very, Ninon\|Steenackers, Agata\|Dubuquoy, Caroline\|Vermuse, Jeanne\|Dubuquoy, Laurent\|Lefebvre, Tony\|El Yazidi-Belkoura, Ikram
PMID:	29524020

599.
Journal:	Oncol Lett. 2018 Apr;15(4):4463-4470.
Title:	Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.
Author:	Han, Chengzheng\|Xing, Guozheng\|Zhang, Mengying\|Zhong, Min\|Han, Zhen\|He, Chiyi\|Liu, Xiaoping
PMID:	29541215

600.
Journal:	Oncol Lett. 2018 Apr;15(4):5465-5472.
Title:	Expression of factors and key components associated with the PI3K signaling pathway in colon cancer.
Author:	Chen, Hua\|Gao, Junyi\|Du, Zhenhua\|Zhang, Xuequn\|Yang, Fei\|Gao, Wei
PMID:	29552187

601.
Journal:	Anticancer Drugs. 2018 Jul;29(6):530-538.
Title:	Celastrol inhibits colorectal cancer cell proliferation and migration through suppression of MMP3 and MMP7 by the PI3K/AKT signaling pathway.
Author:	Bufu, Tang\|Di, Xu\|Yilin, Zhao\|Gege, Liang\|Xi, Chen\|Ling, Wang
PMID:	29553945

602.
Journal:	J Cancer Res Clin Oncol. 2018 Jun;144(6):1049-1063.
Title:	Cartilage oligomeric matrix protein is a prognostic factor and biomarker of colon cancer and promotes cell proliferation by activating the Akt pathway.
Author:	Liu, Ting-Ting\|Liu, Xi-Sheng\|Zhang, Meng\|Liu, Xue-Ni\|Zhu, Fu-Xiang\|Zhu, Fang-Ming\|Ouyang, Si-Wen\|Li, Shan-Bao\|Song, Chen-Long\|Sun, Hui-Min\|Lu, Su\|Zhang, Yu\|Lin, Jun\|Tang, Hua-Mei\|Peng, Zhi-Hai
PMID:	29560517

603.
Journal:	Oncol Rep. 2018 May;39(5):2436-2442.
Title:	Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells.
Author:	Mao, Liyuan\|Chen, Qiongyun\|Gong, Ke\|Xu, Xiaolin\|Xie, Yurou\|Zhang, Wenqing\|Cao, Hanwei\|Hu, Tianhui\|Hong, Xiaoting\|Zhan, Yan-Yan
PMID:	29565467

604.
Journal:	Cell Biochem Funct. 2018 Apr;36(3):116-128.
Title:	Deciphering the molecular mechanism and apoptosis underlying the in-vitro and in-vivo chemotherapeutic efficacy of vanadium luteolin complex in colon cancer.
Author:	Roy, Souvik\|Chakraborty, Tania
PMID:	29574863

605.
Journal:	Oncotarget. 2018 Feb 16;9(18):14306-14310.
Title:	TP53 mutations and number of alterations correlate with maximum standardized uptake value (SUVmax) determined by positron emission tomography/computed tomography (PET/CT) [(18)F] fluorodeoxyglucose ((18)F-FDG PET).
Author:	Chang, Geraldine H\|Kurzrock, Razelle\|Tran, Lisa\|Schwaederle, Maria\|Hoh, Carl K
PMID:	29581845

606.
Journal:	Cancer Res. 2018 Jun 15;78(12):3163-3175.
Title:	Deptor Is a Novel Target of Wnt/beta-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.
Author:	Wang, Qingding\|Zhou, Yuning\|Rychahou, Piotr\|Harris, Jennifer W\|Zaytseva, Yekaterina Y\|Liu, Jinpeng\|Wang, Chi\|Weiss, Heidi L\|Liu, Chunming\|Lee, Eun Y\|Evers, B Mark
PMID:	29666061

607.
Journal:	J Cancer. 2018 Mar 14;9(7):1218-1230.
Title:	MiR-490-3p Functions As a Tumor Suppressor by Inhibiting Oncogene VDAC1 Expression in Colorectal Cancer.
Author:	Liu, Xiangxiang\|He, Bangshun\|Xu, Tao\|Pan, Yuqin\|Hu, Xiuxiu\|Chen, Xiaoxiang\|Wang, Shukui
PMID:	29675103

608.
Journal:	Biomed Pharmacother. 2018 Jul;103:729-737.
Title:	Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells.
Author:	Mou, Jing-Jing\|Peng, Jin\|Shi, Ying-Ying\|Li, Na\|Wang, You\|Ke, Yuan\|Zhou, Yun-Feng\|Zhou, Fu-Xiang
PMID:	29684851

609.
Journal:	Mol Med Rep. 2018 Jun;17(6):8309-8315.
Title:	Knockdown of long noncoding RNA PVT1 reverses multidrug resistance in colorectal cancer cells.
Author:	Fan, Heng\|Zhu, Jian-Hua\|Yao, Xue-Qing
PMID:	29693171

610.
Journal:	Mol Ther. 2018 Jul 5;26(7):1828-1839.
Title:	Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis.
Author:	Li, Jiaqiu\|Song, Ping\|Jiang, Tingting\|Dai, Dongjun\|Wang, Hanying\|Sun, Jie\|Zhu, Liyuan\|Xu, Wenxia\|Feng, Lifeng\|Shin, Vivian Y\|Morrison, Helen\|Wang, Xian\|Jin, Hongchuan
PMID:	29730197

611.
Journal:	Oncotarget. 2018 Apr 13;9(28):19911-19928.
Title:	Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells.
Author:	Kim, Eun-Ji\|Kang, Gyeoung-Jin\|Kang, Jung-Il\|Boo, Hye-Jin\|Hyun, Jin Won\|Koh, Young Sang\|Chang, Weon-Young\|Kim, Young Ree\|Kwon, Jung-Mi\|Maeng, Young Hee\|Yoo, Eun-Sook\|Lee, Chang Hoon\|Kang, Hee-Kyoung
PMID:	29731993

612.
Journal:	Apoptosis. 2018 Jun;23(5-6):356-374.
Title:	Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer.
Author:	Li, Sanhong\|Tian, Jilai\|Zhang, Hongming\|Zhou, Shoubing\|Wang, Xiyong\|Zhang, Lei\|Yang, Jiapeng\|Zhang, Zhigang\|Ji, Zhenling
PMID:	29777330

613.
Journal:	Oncol Lett. 2018 Jun;15(6):8223-8230.
Title:	Asiatic acid inhibits proliferation, migration and induces apoptosis by regulating Pdcd4 via the PI3K/Akt/mTOR/p70S6K signaling pathway in human colon carcinoma cells.
Author:	Hao, Yajuan\|Huang, Jiawei\|Ma, Yun\|Chen, Wancheng\|Fan, Qin\|Sun, Xuegang\|Shao, Meng\|Cai, Hongbing
PMID:	29805556

614.
Journal:	Oncol Lett. 2018 Jun;15(6):9553-9558.
Title:	Tudor-staphylococcal nuclease regulates the expression and biological function of alkylglycerone phosphate synthase via nuclear factor-kappaB and microRNA-127 in human glioma U87MG cells.
Author:	Zhang, Yongqiang\|Jia, Jun\|Li, Ying\|Chen, Yan-Ge\|Huang, Huan\|Qiao, Yang\|Zhu, Yu
PMID:	29805677

615.
Journal:	Diabetes Res Clin Pract. 2018 Sep;143:409-419.
Title:	Metformin in cancer.
Author:	Mallik, Ritwika\|Chowdhury, Tahseen A
PMID:	29807101

616.
Journal:	Oncol Rep. 2018 Aug;40(2):1083-1092.
Title:	Dual mTOR/PI3K inhibitor NVPBEZ235 arrests colorectal cancer cell growth and displays differential inhibition of 4EBP1.
Author:	Alqurashi, Naif\|Hashimi, Saeed M\|Alowaidi, Faisal\|Ivanovski, Saso\|Wei, Ming Q
PMID:	29845289

617.
Journal:	J Ethnopharmacol. 2018 Oct 5;224:140-148.
Title:	Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1alpha/VEGF pathway.
Author:	Peng, Weijun\|Zhang, Shaofang\|Zhang, Zheyu\|Xu, Panpan\|Mao, Dan\|Huang, Siqi\|Chen, Biyue\|Zhang, Chunhu\|Zhang, Sifang
PMID:	29852266

618.
Journal:	Cell Death Dis. 2018 Jun 4;9(6):666.
Title:	Sorting nexin 10 controls mTOR activation through regulating amino-acid metabolism in colorectal cancer.
Author:	Le, Yunchen\|Zhang, Sulin\|Ni, Jiahui\|You, Yan\|Luo, Kejing\|Yu, Yunqiu\|Shen, Xiaoyan
PMID:	29867114

619.
Journal:	Radiother Oncol. 2018 Jun;127(3):361-369.
Title:	Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer.
Author:	de Mey, Sven\|Jiang, Heng\|Wang, Hui\|Engels, Benedikt\|Gevaert, Thierry\|Dufait, Ines\|Feron, Olivier\|Aerts, Joeri\|Verovski, Valeri\|De Ridder, Mark
PMID:	29871814

620.
Journal:	Pathol Oncol Res. 2018 Jun 7. pii: 10.1007/s12253-018-0434-4.
Title:	The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells.
Author:	Sticz, Tamas\|Molnar, Anna\|Danko, Titanilla\|Hujber, Zoltan\|Petovari, Gabor\|Nagy, Noemi\|Vegso, Gyula\|Kopper, Laszlo\|Sebestyen, Anna
PMID:	29882195

621.
Journal:	Exp Mol Med. 2018 Jun 6;50(6):70.
Title:	The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes.
Author:	Wang, Yu-Chu\|Chang, Kung-Chao\|Lin, Bo-Wen\|Lee, Jenq-Chang\|Lai, Chien-Hsien\|Lin, Li-Jyuan\|Yen, Yun\|Lin, Chang-Shen\|Yang, Shiang-Jie\|Lin, Peng-Chan\|Lee, Chung-Ta\|Hung, Liang-Yi
PMID:	29884818

622.
Journal:	Int J Mol Sci. 2018 Jun 14;19(6). pii: ijms19061763.
Title:	Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin.
Author:	Lin, Yueh-Ming\|Chen, Chih-I\|Hsiang, Yi-Ping\|Hsu, Yung-Chia\|Cheng, Kung-Chuan\|Chien, Pei-Hsuan\|Pan, Hsiao-Lin\|Lu, Chien-Chang\|Chen, Yun-Ju
PMID:	29899208

623.
Journal:	Sci Rep. 2018 Jun 15;8(1):9204.
Title:	Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Author:	Fritsche-Guenther, Raphaela\|Zasada, Christin\|Mastrobuoni, Guido\|Royla, Nadine\|Rainer, Roman\|Rossner, Florian\|Pietzke, Matthias\|Klipp, Edda\|Sers, Christine\|Kempa, Stefan
PMID:	29907857

624.
Journal:	Oncogenesis. 2018 Jun 19;7(6):46.
Title:	Effects of immune suppression for transplantation on inflammatory colorectal cancer progression.
Author:	Angriman, Imerio\|Furian, Lucrezia\|Scarpa, Melania\|Fassan, Matteo\|Morgan, Susan\|Porzionato, Andrea\|Kotsafti, Andromachi\|Saadeh, Luca\|Silvestre, Cristina\|De Caro, Raffaele\|Carraro, Amedeo\|Tedeschi, Umberto\|Bardini, Romeo\|Rigotti, Paolo\|Rugge, Massimo\|Castor
PMID:	29915171

625.
Journal:	Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908.
Title:	Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.
Author:	He, Liu-Jun\|Yang, Dong-Lin\|Li, Shi-Qiang\|Zhang, Ya-Jun\|Tang, Yan\|Lei, Jie\|Frett, Brendan\|Lin, Hui-Kuan\|Li, Hong-Yu\|Chen, Zhong-Zhu\|Xu, Zhi-Gang
PMID:	29921474

626.
Journal:	Acta Pharmacol Sin. 2018 Jun 19. pii: 10.1038/s41401-018-0047-1.
Title:	Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy.
Author:	Li, Bin\|Wu, Guo-Liang\|Dai, Wei\|Wang, Gang\|Su, Hao-Yuan\|Shen, Xue-Ping\|Zhan, Rui\|Xie, Jia-Ming\|Wang, Zhong\|Qin, Zheng-Hong\|Gao, Quan-Gen\|Shen, Gen-Hai
PMID:	29921885

627.
Journal:	J Cell Commun Signal. 2018 Jun 11. pii: 10.1007/s12079-018-0471-5.
Title:	Cancer-associated fibroblasts enhance cell proliferation and metastasis of colorectal cancer SW480 cells by provoking long noncoding RNA UCA1.
Author:	Jahangiri, Babak\|Khalaj-Kondori, Mohammad\|Asadollahi, Elahe\|Sadeghizadeh, Majid
PMID:	29948578

628.
Journal:	Biomed Pharmacother. 2018 Oct;106:109-116.
Title:	Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling.
Author:	Tian, Junhong\|Yuan, Leilei
PMID:	29957460

629.
Journal:	J Hematol Oncol. 2018 Jul 3;11(1):89.
Title:	Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression.
Author:	Li, Yang\|Zeng, Changqian\|Hu, Jialei\|Pan, Yue\|Shan, Yujia\|Liu, Bing\|Jia, Li
PMID:	29970122

630.
Journal:	Int J Cancer. 2018 Jul 6.
Title:	Activation of WNT/beta-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations.
Author:	Park, Ye-Lim\|Kim, Hwang-Phill\|Cho, Young-Won\|Min, Dong-Wook\|Cheon, Seul-Ki\|Lim, Yoo Joo\|Song, Sang-Hyun\|Jin Kim, Sung\|Han, Sae-Won\|Park, Kyu Joo\|Kim, Tae-You
PMID:	29978469

631.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2018 Jul 8;47(7):492-498.
Title:	[Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations].
Author:	Yu, L\|Liu, Z Y\|Jiao, J\|Shi, X L\|Cui, W L\|Zhang, W\|Li, Q X
PMID:	29996312

632.
Journal:	J Exp Clin Cancer Res. 2018 Jul 11;37(1):144.
Title:	STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer.
Author:	Wu, Fan\|Gao, Pin\|Wu, Wei\|Wang, Zaozao\|Yang, Jie\|Di, Jiabo\|Jiang, Beihai\|Su, Xiangqian
PMID:	29996891

633.
Journal:	J BUON. 2018 May-Jun;23(3):574-578.
Title:	Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway.
Author:	Zhang, Yibing\|Zhao, Yong\|Guo, Jianyou\|Cui, Haifeng\|Liu, Sha
PMID:	30003721

634.
Journal:	Int J Oncol. 2018 Sep;53(3):1363-1373.
Title:	Active fraction of clove induces apoptosis via PI3K/Akt/mTOR-mediated autophagy in human colorectal cancer HCT-116 cells.
Author:	Liu, Minghua\|Zhao, Ge\|Zhang, Dan\|An, Weixiao\|Lai, Honglin\|Li, Xiaofang\|Cao, Shousong\|Lin, Xiukun
PMID:	30015913

635.
Journal:	Discov Med. 2018 Jun;25(140):265-275.
Title:	miR-212 and mTOR form a regulation loop to modulate autophagy in colorectal adenoma HT-29 cells.
Author:	Ji, Changxue\|Ju, Shuai\|Qiang, Jinwei
PMID:	30021100

636.
Journal:	Dev Reprod. 2018 Jun;22(2):133-142.
Title:	Combination of BEZ235 and Metformin Has Synergistic Effect on Cell Viability in Colorectal Cancer Cells.
Author:	Kim, Taewan\|Kim, Taehyung\|Choi, Soonyoung\|Ko, Hyeran\|Park, Deokbae\|Lee, Youngki
PMID:	30023463

637.
Journal:	Environ Toxicol Pharmacol. 2018 Sep;62:164-176.
Title:	KT2 and RT2 modified antimicrobial peptides derived from Crocodylus siamensis Leucrocin I show activity against human colon cancer HCT-116 cells.
Author:	Maijaroen, Surachai\|Jangpromma, Nisachon\|Daduang, Jureerut\|Klaynongsruang, Sompong
PMID:	30031283

638.
Journal:	ACS Med Chem Lett. 2018 Jun 25;9(7):719-724.
Title:	Discovery of an Orally Bioavailable Dual PI3K/mTOR Inhibitor Based on Sulfonyl-Substituted Morpholinopyrimidines.
Author:	Shen, Sida\|He, Xiangyu\|Yang, Zheng\|Zhang, Liang\|Liu, Yingtao\|Zhang, Zhiyuan\|Wang, Weiwei\|Liu, Wei\|Li, Yufeng\|Huang, Dong\|Sun, Kai\|Ni, Xiaojing\|Yang, Xu\|Chu, Xinxin\|Cui, Yumin\|Lv, Qiang\|Lan, Jiong\|Zhou, Fusheng
PMID:	30034607

639.
Journal:	Biochim Biophys Acta Gen Subj. 2018 Jul 20;1862(10):2281-2292.
Title:	Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1alpha mediated signal pathway.
Author:	Wang, Lin\|Yu, Ziru\|Ren, Shuyue\|Song, Junke\|Wang, Jinhua\|Du, Guanhua
PMID:	30036603

640.
Journal:	Free Radic Biol Med. 2018 Oct;126:41-54.
Title:	Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability.
Author:	Afrin, Sadia\|Giampieri, Francesca\|Forbes-Hernandez, Tamara Y\|Gasparrini, Massimiliano\|Amici, Adolfo\|Cianciosi, Danila\|Quiles, Jose L\|Battino, Maurizio
PMID:	30056083

641.
Journal:	Int J Biol Macromol. 2018 Nov;119:669-676.
Title:	Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Author:	Guo, Songjia\|Liang, Xinxin\|Guo, Min\|Zhang, Xiaoli\|Li, Zhuoyu
PMID:	30071226

642.
Journal:	J Biol Chem. 2018 Sep 21;293(38):14891-14904.
Title:	Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation.
Author:	Boyle, Kathleen A\|Van Wickle, Jonathan\|Hill, R Blake\|Marchese, Adriano\|Kalyanaraman, Balaraman\|Dwinell, Michael B
PMID:	30087121

643.
Journal:	Gene. 2018 Aug 10. pii: S0378-1119(18)30910-7.
Title:	Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Author:	Hu, Min\|Liu, Lisheng\|Yao, Weirong
PMID:	30103008

644.
Journal:	BMC Cancer. 2018 Aug 15;18(1):822.
Title:	Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes.
Author:	Saber, Mona M\|Al-Mahallawi, Abdulaziz M\|Nassar, Noha N\|Stork, Bjorn\|Shouman, Samia A
PMID:	30111296

645.
Journal:	Cancer Lett. 2018 Nov 1;436:119-128.
Title:	Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway.
Author:	Tan, Xiao\|Zhang, Zhongqiang\|Yao, Hongliang\|Shen, Liangfang
PMID:	30118845

646.
Journal:	Biochem Biophys Res Commun. 2018 Sep 18;503(4):3198-3204.
Title:	The influence of aberrant expression of GLI1/p-S6K on colorectal cancer.
Author:	Wang, Xuchao\|Yao, Yizhou\|Zhu, Xinguo
PMID:	30143258

647.
Journal:	Mol Cancer Res. 2018 Sep 10. pii: 1541-7786.MCR-18-0650.
Title:	Repurposing of mTOR Complex inhibitors Attenuates MCL-1 and sensitizes to PARP inhibition.
Author:	Mattoo, Abid R\|Joun, Alex\|Jessup, J Milburn
PMID:	30201826

648.
Journal:	J Cell Physiol. 2018 Sep 10.
Title:	Neratinib augments the lethality of [regorafenib + sildenafil].
Author:	Booth, Laurence\|Roberts, Jane L\|Rais, Rumeesa\|Cutler, Richard E Jr\|Diala, Irmina\|Lalani, Alshad S\|Hancock, John F\|Poklepovic, Andrew\|Dent, Paul
PMID:	30203445

649.
Journal:	Mol Oncol. 2018 Sep 17.
Title:	Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK-1-eIF4G-eIF4E signaling.
Author:	Shen, Peng\|Reineke, Lucas C\|Knutsen, Erik\|Chen, Meng\|Pichler, Martin\|Ling, Hui\|Calin, George A
PMID:	30221473

650.
Journal:	Int J Mol Med. 2018 Nov;42(5):2503-2514.
Title:	MicroRNA-7 inhibits colorectal cancer cell proliferation, migration and invasion via TYRO3 and phosphoinositide 3-kinase/protein B kinase/mammalian target of rapamycin pathway suppression.
Author:	Qin, Ancheng\|Qian, Weifeng
PMID:	30226533

651.
Journal:	Cell Death Dis. 2018 Sep 24;9(10):982.
Title:	SP1-induced lncRNA-ZFAS1 contributes to colorectal cancer progression via the miR-150-5p/VEGFA axis.
Author:	Chen, Xiaoxiang\|Zeng, Kaixuan\|Xu, Mu\|Hu, Xiuxiu\|Liu, Xiangxiang\|Xu, Tao\|He, Bangshun\|Pan, Yuqin\|Sun, Huiling\|Wang, Shukui
PMID:	30250022

652.
Journal:	Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title:	F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author:	Yao, Hui\|Su, Song\|Xia, Dong\|Wang, Mingming\|Li, Zonglin\|Chen, Wangsheng\|Ren, Lei\|Xu, Liang
PMID:	30257389

653.
Journal:	Cancers (Basel). 2018 Sep 25;10(10). pii: cancers10100353.
Title:	Destruxin B Suppresses Drug-Resistant Colon Tumorigenesis and Stemness Is Associated with the Upregulation of miR-214 and Downregulation of mTOR/beta-Catenin Pathway.
Author:	Wu, Szu-Yuan\|Huang, Yan-Jiun\|Tzeng, Yew-Min\|Huang, Chi-Ying F\|Hsiao, Michael\|Wu, Alexander T H\|Huang, Tse-Hung
PMID:	30257507

654.
Journal:	Evid Based Complement Alternat Med. 2018 Sep 12;2018:5149436.
Title:	(+)-Usnic Acid Inhibits Migration of c-KIT Positive Cells in Human Colorectal Cancer.
Author:	Wu, Wei\|Hou, Bing\|Tang, Changli\|Liu, Fucheng\|Yang, Jie\|Pan, Tao\|Si, Ke\|Lu, Deyun\|Wang, Xiaoxiang\|Wang, Jing\|Xiong, Xing\|Liu, Ji\|Xie, Chunguang
PMID:	30298093

655.
Journal:	PLoS One. 2018 Oct 11;13(10):e0205449.
Title:	Anti-metastatic effect of metformin via repression of interleukin 6-induced epithelial-mesenchymal transition in human colon cancer cells.
Author:	Kang, Sanghee\|Kim, Bo Ram\|Kang, Myoung-Hee\|Kim, Dae-Young\|Lee, Dae-Hee\|Oh, Sang Cheul\|Min, Byung Wook\|Um, Jun Won
PMID:	30308035

656.
Journal:	J Cell Biochem. 2018 Oct 15.
Title:	Silencing of FOXO6 inhibits the proliferation, invasion, and glycolysis in colorectal cancer cells.
Author:	Li, Quanying\|Tang, Hongna\|Hu, Fangfang\|Qin, Changjiang
PMID:	30321450

657.
Journal:	J Cell Physiol. 2018 Oct 26.
Title:	Knockdown of long noncoding RNA urothelial carcinoma associated 1 inhibits colorectal cancer cell proliferation and promotes apoptosis via modulating autophagy.
Author:	Song, Fengling\|Li, Lexing\|Liang, Danyang\|Zhuo, Yisha\|Wang, Xueyi\|Dai, Hanchuan
PMID:	30362538

658.
Journal:	Int Immunopharmacol. 2018 Oct 30;65:429-437.
Title:	Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1alpha nuclear translocation.
Author:	Zhang, Lin\|Chen, Chang\|Duanmu, Jiaxin\|Wu, Yan\|Tao, Jinhua\|Yang, Aihua\|Yin, Xiaoqin\|Xiong, Biao\|Gu, Jingya\|Li, Chunling\|Liu, Zhaoguo
PMID:	30388517