Primary Site >> Esophagus Cancer

Gene >> MTHFR

Journal: Cancer Epidemiol Biomarkers Prev. 2002 Nov;11(11):1454-8.
Title: Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.
Author: Miao, Xiaoping|Xing, Deyin|Tan, Wen|Qi, Jun|Lu, Wenfu|Lin, Dongxin
PMID: 12433726
Journal: Oncol Rep. 2003 Sep-Oct;10(5):1615-23.
Title: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Author: Xing, Deyin|Tan, Wen|Lin, Dongxin
PMID: 12883749
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Apr;25(4):341-5.
Title: [A case-control study on the polymorphisms of methylenetetrahydrofolate reductase 1298A-->C and susceptibility of esophageal cancer].
Author: Gao, Chang-ming|Toshiro, Takezaki|Wu, Jian-zhong|Cao, Hai-xia|Liu, Yan-ting|Ding, Jian-hua|Li, Su-ping|Su, Ping|Hu, Xu|Kai, Hai-tao|Kazuo, Tajima
PMID: 15231206
Journal: J Cancer Res Clin Oncol. 2004 Oct;130(10):574-80. Epub 2004 Jul 29.
Title: Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
Author: Zhang, Jianhui|Zotz, Rainer B|Li, Yan|Wang, Rui|Kiel, Sybille|Schulz, Wolfgang A|Wen, Denggui|Chen, Zhifeng|Zhang, Liwei|Wang, Shijie|Gabbert, Helmut E|Sarbia, Mario
PMID: 15449187
Journal: Carcinogenesis. 2005 Jul;26(7):1285-90. Epub 2005 Mar 24.
Title: Gene-environment interactions between alcohol drinking and the MTHFR C677T polymorphism impact on esophageal cancer risk: results of a case-control study in Japan.
Author: Yang, Chun-Xia|Matsuo, Keitaro|Ito, Hidemi|Shinoda, Masayuki|Hatooka, Shunzo|Hirose, Kaoru|Wakai, Kenji|Saito, Toshiko|Suzuki, Takeshi|Maeda, Takako|Tajima, Kazuo
PMID: 15790587
Journal: J Clin Oncol. 2006 Aug 10;24(23):3789-98. Epub 2006 Jun 19.
Title: Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer.
Author: Wu, Xifeng|Gu, Jian|Wu, Tsung-Teh|Swisher, Stephen G|Liao, Zhongxin|Correa, Arlene M|Liu, Jun|Etzel, Carol J|Amos, Christopher I|Huang, Maosheng|Chiang, Silvia S|Milas, Luke|Hittelman, Walter N|Ajani, Jaffer A
PMID: 16785472
Journal: Adv Exp Med Biol. 2006;587:115-20.
Title: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
Author: Hofler, Heinz|Langer, Rupert|Ott, Katja|Keller, Gisela
PMID: 17163161
Journal: Recent Results Cancer Res. 2007;176:33-6.
Title: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
Author: Hofler, Heinz|Langer, Rupert|Ott, Katja|Keller, Gisela
PMID: 17607914
Journal: Int J Cancer. 2007 Oct 15;121(8):1643-58.
Title: Genetic polymorphisms and esophageal cancer risk.
Author: Hiyama, Toru|Yoshihara, Masaharu|Tanaka, Shinji|Chayama, Kazuaki
PMID: 17674367
Journal: Arch Med Res. 2008 Aug;39(6):594-600.
Title: Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.
Author: Li, Daqing|Diao, Yutao|Li, Hao|Fang, Xueqiang|Li, Huiqing
PMID: 18662591
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Jan;29(1):30-3.
Title: [Study on the ingestion of folate and polymorphism of MTHFR C677T with esophageal cancer in Xinjiang Kazakh].
Author: Qin, Jiang-mei|Wang, Xiu-mei|Chen, Bo|Yang, Lei|Li, Feng|He, Ling|Liao, Pei-hua
PMID: 18785474
Journal: World J Gastroenterol. 2008 Dec 7;14(45):6986-92.
Title: Interaction of methylenetetrahydrofolate reductase C677T, cytochrome P4502E1 polymorphism and environment factors in esophageal cancer in Kazakh population.
Author: Qin, Jiang-Mei|Yang, Lei|Chen, Bo|Wang, Xiu-Mei|Li, Feng|Liao, Pei-Hua|He, Lin
PMID: 19058336
Journal: Ai Zheng. 2008 Dec;27(12):1256-62.
Title: [Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma].
Author: Xue, Heng-Chuan|Wang, Jian-Ming|Xu, Biao|Guo, Guo-Ping|Hua, Zhao-Lai|Zhou, Qin|Zhu, Zong-Hai|Ma, Zhen-Kai|Gao, Jie
PMID: 19079989
Journal: Toxicol Lett. 2009 Jan 30;184(2):73-80.
Title: Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer.
Author: Langevin, S M|Lin, D|Matsuo, K|Gao, C M|Takezaki, T|Stolzenberg-Solomon, R Z|Vasavi, M|Hasan, Q|Taioli, E
PMID: 18840514
Journal: BMC Gastroenterol. 2011 Jun 14;11:74.
Title: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County.
Author: Li, Qing Da|Li, Hao|Wang, Mei Shu|Diao, Tao Yu|Zhou, Zhi Ying|Fang, Qiang Xue|Yang, Fang Yan|Li, Qing Hui
PMID: 21672255
Journal: Asian Pac J Cancer Prev. 2011;12(8):2019-23.
Title: Folate intake, methylenetetrahydrofolate reductase polymorphisms, and risk of esophageal cancer.
Author: Zhao, Pengcheng|Lin, Fengsong|Li, Zhe|Lin, Baisong|Lin, Jing|Luo, Rongcheng
PMID: 22292644
Journal: Ann Surg Oncol. 2011 Sep;18(9):2688-98.
Title: DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy.
Author: Ott, Katja|Rachakonda, P Sivaramakrishna|Panzram, Benjamin|Keller, Gisela|Lordick, Florian|Becker, Karen|Langer, Rupert|Buechler, Markus|Hemminki, Kari|Kumar, Rajiv
PMID: 21347786
Journal: Int J Cancer. 2011 Feb 1;128(3):644-52.
Title: Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
Author: Zacho, Jeppe|Yazdanyar, Shiva|Bojesen, Stig E|Tybjaerg-Hansen, Anne|Nordestgaard, Borge G
PMID: 20473868
Journal: Asian Pac J Cancer Prev. 2011;12(1):247-52.
Title: Meta-analysis of the relationship between the Metholenetetrahydrofolate reductase C677T genetic polymorphism, folate intake and esophageal cancer.
Author: Liu, Yi-Xia|Wang, Bin|Wan, Mei-Hua|Tang, Wen-Fu|Huang, Fu-Kai|Li, Chengwen
PMID: 21517266
Journal: Dis Esophagus. 2012 Jul;25(5):437-41.
Title: Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Author: Ekiz, F|Ormeci, N|Coban, S|Karabulut, H G|Aktas, B|Tukun, A|Tuncali, T|Yuksel, O|Alkis, N
PMID: 21951971
Journal: Asian Pac J Cancer Prev. 2012;13(2):647-51.
Title: Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
Author: Jing, Chen|Huang, Zhijie|Duan, Yuqin|Xiao, Xinrong|Zhang, Ru|Jiang, Jianqing
PMID: 22524840
Journal: Asian Pac J Cancer Prev. 2013;14(1):21-5.
Title: Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: a meta-analysis of case-control studies.
Author: Wen, Yuan-Yuan|Yang, Shu-Juan|Zhang, Jian-Xing|Chen, Xin-Yue
PMID: 23534726
Journal: Asian Pac J Cancer Prev. 2013;14(3):1951-5.
Title: Genetic polymorphism of MTHFR A1298C and esophageal cancer susceptibility: a meta-analysis.
Author: Tan, Xiang|Wang, Yong-Yong|Dai, Lei|Liao, Xu-Qiang|Chen, Ming-Wu
PMID: 23679298
Journal: Asian Pac J Cancer Prev. 2013;14(5):3163-8.
Title: The methylenetetrahydrofolate reductase C677T polymorphism influences risk of esophageal cancer in Chinese.
Author: Qu, Hong-Hong|Cui, Li-Hong|Wang, Ke|Wang, Peng|Song, Chun-Hua|Wang, Kai-Juan|Zhang, Jian-Ying|Dai, Li-Ping
PMID: 23803097
Journal: Pak J Med Sci. 2013 Apr;29(2):693-8.
Title: Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: A meta-analysis of case-control studies.
Author: Shujuan, Yang|Jianxing, Zhang|Xin-Yue, Chen
PMID: 24353609
Journal: Asian Pac J Cancer Prev. 2014;15(3):1345-9.
Title: Methylenetetrahydrofolate reductase polymorphisms and susceptibility to esophageal cancer in Chinese populations: a meta-analysis.
Author: Yang, Yong-Bin|Shang, Yan-Hong|Tan, Yan-Li|Kang, Xian-Jiang|Meng, Ming|Zhao, Zhan-Xue
PMID: 24606463
Journal: PLoS One. 2014 Oct 22;9(10):e109235.
Title: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Author: Chang, Shen-Chih|Chang, Po-Yin|Butler, Brendan|Goldstein, Binh Y|Mu, Lina|Cai, Lin|You, Nai-Chieh Y|Baecker, Aileen|Yu, Shun-Zhang|Heber, David|Lu, Qing-Yi|Li, Liming|Greenland, Sander|Zhang, Zuo-Feng
PMID: 25337902
Journal: Wei Sheng Yan Jiu. 2014 Mar;43(2):254-8.
Title: [MTHFR C677T polymorphism and genetic susceptibility of esophageal cancer and esophageal precancerous lesions].
Author: Huang, Guiling|Wang, Shaokang|Su, Ming|Wang, Tingting|Yin, Hong|Sun, Guiju
PMID: 24868979
Journal: Med Oncol. 2014 May;31(5):915.
Title: Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population.
Author: Tang, Weifeng|Zhang, Sheng|Qiu, Hao|Wang, Lixin|Sun, Bin|Yin, Jun|Gu, Haiyong
PMID: 24687778
Journal: Ann Oncol. 2015 Apr;26(4):624-44.
Title: A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.
Author: Findlay, J M|Middleton, M R|Tomlinson, I
PMID: 25214541
Journal: Med Sci Monit. 2015 Oct 12;21:3068-76.
Title: MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.
Author: Zhao, Yue|Li, Xingde|Kong, Xiangjun
PMID: 26456456
Journal: Indian J Cancer. 2015 Nov;52 Suppl 1:e26-8.
Title: Methylene tetrahydrofolate reductasel reductase C677T polymorphisms and esophageal cancer susceptibility: A meta-analysis based on Chinese Han population.
Author: Yang, Z|Wang, X|Li, S
PMID: 26548935
Journal: Pharmacogenomics J. 2016 Jun;16(3):249-65.
Title: Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis.
Author: Salnikova, L E|Kolobkov, D S
PMID: 26122021
Journal: J Cancer. 2018 Jul 30;9(16):2865-2875.
Title: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
Author: Dong, Yin|Yi, Xu|Yujie, Zhen|Huixia, Zhang|Yan, Chen
PMID: 30123355