Primary Site >> Esophagus Cancer

Gene >> MTHFR

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Ref: Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.
PMID: 12433726
Ref: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
PMID: 12883749
Ref: [A case-control study on the polymorphisms of methylenetetrahydrofolate reductase 1298A-->C and susceptibility of esophageal cancer].
PMID: 15231206
Ref: Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
PMID: 15449187
Ref: Gene-environment interactions between alcohol drinking and the MTHFR C677T polymorphism impact on esophageal cancer risk: results of a case-control study in Japan.
PMID: 15790587
Ref: Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer.
PMID: 16785472
Ref: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
PMID: 17163161
Ref: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
PMID: 17607914
Ref: Genetic polymorphisms and esophageal cancer risk.
PMID: 17674367
Ref: Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.
PMID: 18662591
Ref: [Study on the ingestion of folate and polymorphism of MTHFR C677T with esophageal cancer in Xinjiang Kazakh].
PMID: 18785474
Ref: Interaction of methylenetetrahydrofolate reductase C677T, cytochrome P4502E1 polymorphism and environment factors in esophageal cancer in Kazakh population.
PMID: 19058336
Ref: [Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma].
PMID: 19079989
Ref: Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer.
PMID: 18840514
Ref: Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
PMID: 20473868
Ref: DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy.
PMID: 21347786
Ref: Meta-analysis of the relationship between the Metholenetetrahydrofolate reductase C677T genetic polymorphism, folate intake and esophageal cancer.
PMID: 21517266
Ref: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County.
PMID: 21672255
Ref: Folate intake, methylenetetrahydrofolate reductase polymorphisms, and risk of esophageal cancer.
PMID: 22292644
Ref: Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
PMID: 21951971
Ref: Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
PMID: 22524840
Ref: Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: a meta-analysis of case-control studies.
PMID: 23534726
Ref: Genetic polymorphism of MTHFR A1298C and esophageal cancer susceptibility: a meta-analysis.
PMID: 23679298
Ref: The methylenetetrahydrofolate reductase C677T polymorphism influences risk of esophageal cancer in Chinese.
PMID: 23803097
Ref: Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: A meta-analysis of case-control studies.
PMID: 24353609
Ref: Methylenetetrahydrofolate reductase polymorphisms and susceptibility to esophageal cancer in Chinese populations: a meta-analysis.
PMID: 24606463
Ref: Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population.
PMID: 24687778
Ref: [MTHFR C677T polymorphism and genetic susceptibility of esophageal cancer and esophageal precancerous lesions].
PMID: 24868979
Ref: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
PMID: 25337902
Ref: A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.
PMID: 25214541
Ref: MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.
PMID: 26456456
Ref: Methylene tetrahydrofolate reductasel reductase C677T polymorphisms and esophageal cancer susceptibility: A meta-analysis based on Chinese Han population.
PMID: 26548935
Ref: Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis.
PMID: 26122021
Ref: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
PMID: 30123355