Primary Site >> Pancreatic Cancer
Gene >> MST1R
| 1. | |||||||||||
| Journal: | Cancer Res. 2004 Aug 1;64(15):5154-61. | ||||||||||
| Title: | Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression. | ||||||||||
| Author: | Bardella, Chiara|Costa, Barbara|Maggiora, Piera|Patane', Salvatore|Olivero, Martina|Ranzani, Guglielmina N|De Bortoli, Michele|Comoglio, Paolo M|Di Renzo, Maria Flavia | ||||||||||
| PMID: | 15289319 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2006 Sep 15;66(18):9162-70. | ||||||||||
| Title: | Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. | ||||||||||
| Author: | O'Toole, Jennifer M|Rabenau, Karen E|Burns, Kerri|Lu, Dan|Mangalampalli, Venkat|Balderes, Paul|Covino, Nicole|Bassi, Rajiv|Prewett, Marie|Gottfredsen, Kimberly J|Thobe, Megan N|Cheng, Yuan|Li, Yiwen|Hicklin, Daniel J|Zhu, Zhenping|Waltz, Susan E|Hayman, M | ||||||||||
| PMID: | 16982759 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer. 2007 Mar 15;109(6):1030-9. | ||||||||||
| Title: | Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target. | ||||||||||
| Author: | Camp, E Ramsay|Yang, Anthony|Gray, Mike J|Fan, Fan|Hamilton, Stanley R|Evans, Douglas B|Hooper, Andrea T|Pereira, Daniel S|Hicklin, Daniel J|Ellis, Lee M | ||||||||||
| PMID: | 17311308 | ||||||||||
| 4. | |||||||||||
| Journal: | J Biol Chem. 2008 Apr 25;283(17):11293-301. | ||||||||||
| Title: | Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells. | ||||||||||
| Author: | Zhao, Shujie|Ammanamanchi, Sudhakar|Brattain, Michael|Cao, Lin|Thangasamy, Amalraj|Wang, Jing|Freeman, James W | ||||||||||
| PMID: | 18310076 | ||||||||||
| 5. | |||||||||||
| Journal: | Vet Ital. 2009 Jan-Mar;45(1):209. | ||||||||||
| Title: | In memoriam: Great 21st century physician 'One Health' leader dies - Ronald M. Davis, MD, Past President, American Medical Association. | ||||||||||
| Author: | Kahn, Laura H|Kaplan, Bruce|Monath, Thomas P | ||||||||||
| PMID: | 20391399 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2010 Feb 1;70(3):1130-40. | ||||||||||
| Title: | Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. | ||||||||||
| Author: | Logan-Collins, Jocelyn|Thomas, Ryan M|Yu, Peter|Jaquish, Dawn|Mose, Evangeline|French, Randall|Stuart, William|McClaine, Rebecca|Aronow, Bruce|Hoffman, Robert M|Waltz, Susan E|Lowy, Andrew M | ||||||||||
| PMID: | 20103639 | ||||||||||
| 7. | |||||||||||
| Journal: | Pancreas. 2010 Apr;39(3):301-7. | ||||||||||
| Title: | The RON tyrosine kinase receptor regulates vascular endothelial growth factor production in pancreatic cancer cells. | ||||||||||
| Author: | Thomas, Ryan M|Jaquish, Dawn V|French, Randall P|Lowy, Andrew M | ||||||||||
| PMID: | 20358644 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Oncol. 2010 Jun;36(6):1551-61. | ||||||||||
| Title: | Inhibition of MSP-RON signaling pathway in cancer cells by a novel soluble form of RON comprising the entire sema sequence. | ||||||||||
| Author: | Ma, Qi|Zhang, Kun|Yao, Hang-Ping|Zhou, Yong-Qing|Padhye, Snehal|Wang, Ming-Hai | ||||||||||
| PMID: | 20428780 | ||||||||||
| 9. | |||||||||||
| Journal: | Acta Pharmacol Sin. 2010 Sep;31(9):1181-8. | ||||||||||
| Title: | Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy. | ||||||||||
| Author: | Wang, Ming-Hai|Padhye, Snehal S|Guin, Sunny|Ma, Qi|Zhou, Yong-qing | ||||||||||
| PMID: | 20694025 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Pharm. 2011 Dec 5;8(6):2310-9. | ||||||||||
| Title: | Sustained expression of the RON receptor tyrosine kinase by pancreatic cancer stem cells as a potential targeting moiety for antibody-directed chemotherapeutics. | ||||||||||
| Author: | Padhye, Snehal S|Guin, Sunny|Yao, Hang-Ping|Zhou, Yong-Qing|Zhang, Ruiwen|Wang, Ming-Hai | ||||||||||
| PMID: | 22014215 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer. 2011 May 28;10:66. | ||||||||||
| Title: | Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein. | ||||||||||
| Author: | Ma, Qi|Guin, Sunny|Padhye, Snehal S|Zhou, Yong-Qing|Zhang, Rui-Wen|Wang, Ming-Hai | ||||||||||
| PMID: | 21619683 | ||||||||||
| 12. | |||||||||||
| Journal: | Carcinogenesis. 2011 Aug;32(8):1151-6. | ||||||||||
| Title: | IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration. | ||||||||||
| Author: | Jaquish, Dawn V|Yu, Peter T|Shields, David J|French, Randall P|Maruyama, Karly P|Niessen, Sherry|Hoover, Heather|A Cheresh, David|Cravatt, Ben|Lowy, Andrew M | ||||||||||
| PMID: | 21565828 | ||||||||||
| 13. | |||||||||||
| Journal: | Anticancer Res. 2012 Feb;32(2):427-37. | ||||||||||
| Title: | Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors. | ||||||||||
| Author: | Moser, Christian|Lang, Sven A|Hackl, Christina|Zhang, Hong|Lundgren, Karen|Hong, Victor|McKenzie, Andres|Weber, Bernhard|Park, Jung S|Schlitt, Hans J|Geissler, Edward K|Jung, Young D|Stoeltzing, Oliver | ||||||||||
| PMID: | 22287729 | ||||||||||
| 14. | |||||||||||
| Journal: | BMC Cancer. 2012 Sep 7;12:395. | ||||||||||
| Title: | RON is not a prognostic marker for resectable pancreatic cancer. | ||||||||||
| Author: | Tactacan, Carole M|Chang, David K|Cowley, Mark J|Humphrey, Emily S|Wu, Jianmin|Gill, Anthony J|Chou, Angela|Nones, Katia|Grimmond, Sean M|Sutherland, Robert L|Biankin, Andrew V|Daly, Roger J | ||||||||||
| PMID: | 22958871 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 Jan;13(1):37-48. | ||||||||||
| Title: | Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells. | ||||||||||
| Author: | Zeng, Jun-Ying|Sharma, Sharad|Zhou, Yong-Qing|Yao, Hang-Ping|Hu, Xing|Zhang, Ruiwen|Wang, Ming-Hai | ||||||||||
| PMID: | 24233399 | ||||||||||
| 16. | |||||||||||
| Journal: | Pancreas. 2014 Mar;43(2):183-9. | ||||||||||
| Title: | The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies. | ||||||||||
| Author: | Kang, Chang Moo|Babicky, Michele L|Lowy, Andrew M | ||||||||||
| PMID: | 24518495 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncogene. 2016 Jun 23;35(25):3249-59. | ||||||||||
| Title: | A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells. | ||||||||||
| Author: | Chakedis, J|French, R|Babicky, M|Jaquish, D|Howard, H|Mose, E|Lam, R|Holman, P|Miyamoto, J|Walterscheid, Z|Lowy, A M | ||||||||||
| PMID: | 26477314 | ||||||||||
| 18. | |||||||||||
| Journal: | Am J Cancer Res. 2016 May 1;6(5):937-56. eCollection 2016. | ||||||||||
| Title: | Therapeutic evaluation of monoclonal antibody-maytansinoid conjugate as a model of RON-targeted drug delivery for pancreatic cancer treatment. | ||||||||||
| Author: | Yao, Hang-Ping|Feng, Liang|Zhou, Jian-Wei|Zhang, Rui-Wen|Wang, Ming-Hai | ||||||||||
| PMID: | 27293990 | ||||||||||
| 19. | |||||||||||
| Journal: | Anticancer Drugs. 2016 Sep;27(8):766-79. | ||||||||||
| Title: | Analogs of the hepatocyte growth factor and macrophage-stimulating protein hinge regions act as Met and Ron dual inhibitors in pancreatic cancer cells. | ||||||||||
| Author: | Church, Kevin J|Vanderwerff, Brett R|Riggers, Rachelle R|McMicheal, Michelle D|Mateo-Victoriano, Beatriz|Sukumar, Sudharsan R|Harding, Joseph W | ||||||||||
| PMID: | 27314431 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 24;8(4):5885-5894. | ||||||||||
| Title: | A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts. | ||||||||||
| Author: | Hoover, Malachia|Adamian, Yvess|Brown, Mark|Maawy, Ali|Chang, Alexander|Lee, Jacqueline|Gharibi, Armen|Katz, Matthew H|Fleming, Jason|Hoffman, Robert M|Bouvet, Michael|Doebler, Robert|Kelber, Jonathan A | ||||||||||
| PMID: | 27602776 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2017 Aug 24;8(41):71105-71116. | ||||||||||
| Title: | Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network. | ||||||||||
| Author: | Zhang, Tiejun|Wang, Xiaojuan|Yue, Zhenyu | ||||||||||
| PMID: | 29050346 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Pharm. 2018 Aug 6;15(8):3260-3271. | ||||||||||
| Title: | Preclinical Efficacy of Anti-RON Antibody-Drug Conjugate Zt/g4-MMAE for Targeted Therapy of Pancreatic Cancer Overexpressing RON Receptor Tyrosine Kinase. | ||||||||||
| Author: | Yao, Hang-Ping|Feng, Liang|Weng, Tian-Hao|Hu, Chen-Yu|Suthe, Sreedhar Reddy|Mostofa, A G M|Chen, Ling-Hui|Wu, Zhi-Gang|Wang, Wei-Lin|Wang, Ming-Hai | ||||||||||
| PMID: | 29944378 | ||||||||||