Primary Site >> Colorectal Cancer

Gene >> MSH3

Journal: Curr Opin Genet Dev. 1997 Feb;7(1):105-13.
Title: MutS homologs in mammalian cells.
Author: Fishel, R|Wilson, T
PMID: 9024626
Journal: Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10144-9.
Title: DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair.
Author: Drummond, J T|Genschel, J|Wolf, E|Modrich, P
PMID: 9294177
Journal: Cancer Res. 1997 Sep 15;57(18):3920-3.
Title: Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.
Author: Akiyama, Y|Sato, H|Yamada, T|Nagasaki, H|Tsuchiya, A|Abe, R|Yuasa, Y
PMID: 9307272
Journal: Cancer Res. 1997 Oct 1;57(19):4420-6.
Title: Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype.
Author: Yamamoto, H|Sawai, H|Perucho, M
PMID: 9331106
Journal: Hum Mutat. 1997;10(6):474-8.
Title: Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.
Author: Yin, J|Kong, D|Wang, S|Zou, T T|Souza, R F|Smolinski, K N|Lynch, P M|Hamilton, S R|Sugimura, H|Powell, S M|Young, J|Abraham, J M|Meltzer, S J
PMID: 9401011
Journal: Oncogene. 1997 Dec 4;15(23):2877-81.
Title: Drastic genetic instability of tumors and normal tissues in Turcot syndrome.
Author: Miyaki, M|Nishio, J|Konishi, M|Kikuchi-Yanoshita, R|Tanaka, K|Muraoka, M|Nagato, M|Chong, J M|Koike, M|Terada, T|Kawahara, Y|Fukutome, A|Tomiyama, J|Chuganji, Y|Momoi, M|Utsunomiya, J
PMID: 9419979
Journal: Cancer Res. 1998 Feb 15;58(4):594-8.
Title: Close correlation between mutations of E2F4 and hMSH3 genes in colorectal cancers with microsatellite instability.
Author: Ikeda, M|Orimo, H|Moriyama, H|Nakajima, E|Matsubara, N|Mibu, R|Tanaka, N|Shimada, T|Kimura, A|Shimizu, K
PMID: 9485005
Journal: Carcinogenesis. 1998 Feb;19(2):247-51.
Title: RER phenotype and its associated mutations in familial gastric cancer.
Author: Shinmura, K|Tani, M|Isogaki, J|Wang, Y|Sugimura, H|Yokota, J
PMID: 9498272
Journal: Cancer Res. 1998 Mar 1;58(5):997-1003.
Title: Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer.
Author: Yamamoto, H|Sawai, H|Weber, T K|Rodriguez-Bigas, M A|Perucho, M
PMID: 9500462
Journal: J Biol Chem. 1998 Jul 31;273(31):19895-901.
Title: Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha.
Author: Genschel, J|Littman, S J|Drummond, J T|Modrich, P
PMID: 9677427
Journal: Pathol Int. 1998 Aug;48(8):586-94.
Title: Microsatellite instability in young patients with colorectal cancer.
Author: Kim, W H|Lee, H W|Park, S H|Kim, Y I|Chi, J G
PMID: 9736405
Journal: Carcinogenesis. 1998 Nov;19(11):1925-9.
Title: Allelic losses and DNA methylation at DNA mismatch repair loci in sporadic colorectal cancer.
Author: Benachenhou, N|Guiral, S|Gorska-Flipot, I|Michalski, R|Labuda, D|Sinnett, D
PMID: 9855004
Journal: Oncologist. 1998;3(5):319-338.
Title: Hereditary Factors in Gynecologic Cancer.
Author: Lynch|Casey|Shaw|Lynch
PMID: 10388122
Journal: Cancer Res. 1999 Jan 15;59(2):462-6.
Title: Causes and consequences of microsatellite instability in endometrial carcinoma.
Author: Gurin, C C|Federici, M G|Kang, L|Boyd, J
PMID: 9927063
Journal: J Hum Genet. 1999;44(1):18-21.
Title: Germline mutations in a polycytosine repeat of the hMSH6 gene in Korean hereditary nonpolyposis colorectal cancer.
Author: Shin, K H|Ku, J L|Park, J G
PMID: 9929971
Journal: Gastroenterology. 1999 Jun;116(6):1348-57.
Title: Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features.
Author: Yamamoto, H|Perez-Piteira, J|Yoshida, T|Terada, M|Itoh, F|Imai, K|Perucho, M
PMID: 10348818
Journal: Genes Chromosomes Cancer. 1999 Oct;26(2):106-14.
Title: Regional reproducibility of microsatellite instability in sporadic colorectal cancer.
Author: Samowitz, W S|Slattery, M L
PMID: 10469448
Journal: Mol Cell Biol. 1999 Nov;19(11):7558-67.
Title: Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination.
Author: Studamire, B|Price, G|Sugawara, N|Haber, J E|Alani, E
PMID: 10523644
Journal: Nat Genet. 1999 Nov;23(3):359-62.
Title: HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions.
Author: de Wind, N|Dekker, M|Claij, N|Jansen, L|van Klink, Y|Radman, M|Riggins, G|van der Valk, M|van't Wout, K|te Riele, H
PMID: 10545954
Journal: Oncogene. 1999 Nov 18;18(48):6806-9.
Title: Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability.
Author: Duval, A|Iacopetta, B|Ranzani, G N|Lothe, R A|Thomas, G|Hamelin, R
PMID: 10597289
Journal: Oncogene. 1999 Dec 23;18(56):8044-7.
Title: Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.
Author: Bader, S|Walker, M|Hendrich, B|Bird, A|Bird, C|Hooper, M|Wyllie, A
PMID: 10637515
Journal: Jpn J Cancer Res. 1999 Dec;90(12):1310-5.
Title: Frameshift mutations and a length polymorphism in the hMSH3 gene and the spectrum of microsatellite instability in sporadic colon cancer.
Author: Orimo, H|Nakajima, E|Ikejima, M|Emi, M|Shimada, T
PMID: 10665647
Journal: Eur J Cancer. 1999 Nov;35(12):1724-9.
Title: Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Author: Ku, J L|Yoon, K A|Kim, D Y|Park, J G
PMID: 10674020
Journal: Int J Gynecol Cancer. 1999 Jan;9(1):67-71.
Title: Analysis of microsatellite instability in cervical cancer.
Author: Ou, C.-Y.|Chang, J.-G.|Tseng, H.-H.|Wei, H.-J.|Su, T.-H.|Hsu, T.-Y.|Chang, C.-P.|Lee, H.-H.
PMID: 11240745
Journal: Int J Oncol. 2000 Jan;16(1):133-9.
Title: The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences.
Author: Johannsdottir, J T|Jonasson, J G|Bergthorsson, J T|Amundadottir, L T|Magnusson, J|Egilsson, V|Ingvarsson, S
PMID: 10601558
Journal: Hum Mol Genet. 2000 Jan 22;9(2):283-7.
Title: Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis.
Author: Guanti, G|Resta, N|Simone, C|Cariola, F|Demma, I|Fiorente, P|Gentile, M
PMID: 10607839
Journal: Int J Oncol. 2000 Apr;16(4):731-7.
Title: Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium.
Author: Semba, S|Ouyang, H|Han, S Y|Kato, Y|Horii, A
PMID: 10717241
Journal: Gynecol Oncol. 2000 Apr;77(1):18-25.
Title: Atypical clustering of gynecologic malignancies: A family study including molecular analysis of candidate genes.
Author: Cohn, D E|Babb, S|Whelan, A J|Mutch, D G|Herzog, T J|Rader, J S|Elbendary, A|Goodfellow, P J
PMID: 10739686
Journal: Curr Opin Genet Dev. 2000 Apr;10(2):157-61.
Title: Mismatch repair defects in cancer.
Author: Jiricny, J|Nystrom-Lahti, M
PMID: 10753784
Journal: Cancer Res. 2000 Apr 15;60(8):2225-31.
Title: HMSH6 alterations in patients with microsatellite instability-low colorectal cancer.
Author: Parc, Y R|Halling, K C|Wang, L|Christensen, E R|Cunningham, J M|French, A J|Burgart, L J|Price-Troska, T L|Roche, P C|Thibodeau, S N
PMID: 10786688
Journal: Gut. 2000 Jul;47(1):37-42.
Title: DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
Author: Iino, H|Simms, L|Young, J|Arnold, J|Winship, I M|Webb, S I|Furlong, K L|Leggett, B|Jass, J R
PMID: 10861262
Journal: Gut. 2000 Jul;47(1):43-9.
Title: Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
Author: Jass, J R|Iino, H|Ruszkiewicz, A|Painter, D|Solomon, M J|Koorey, D J|Cohn, D|Furlong, K L|Walsh, M D|Palazzo, J|Edmonston, T B|Fishel, R|Young, J|Leggett, B A
PMID: 10861263
Journal: Genes Chromosomes Cancer. 2000 Sep;29(1):33-9.
Title: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation.
Author: Planck, M|Wenngren, E|Borg, A|Olsson, H|Nilbert, M
PMID: 10918391
Journal: Am J Pathol. 2000 Aug;157(2):347-52.
Title: Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer.
Author: Loukola, A|Vilkki, S|Singh, J|Launonen, V|Aaltonen, L A
PMID: 10934138
Journal: J Hum Genet. 2000;45(4):228-30.
Title: Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability.
Author: Orimo, H|Nakajima, E|Yamamoto, M|Ikejima, M|Emi, M|Shimada, T
PMID: 10944853
Journal: Genes Chromosomes Cancer. 2000 Oct;29(2):130-6.
Title: Mutations associated with microsatellite unstable colorectal carcinomas exhibit widespread intratumoral heterogeneity.
Author: Barnetson, R|Jass, J|Tse, R|Eckstein, R|Robinson, B|Schnitzler, M
PMID: 10959092
Journal: J Surg Oncol. 2000 Aug;74(4):249-56.
Title: Genetic alterations of sporadic colorectal cancer with microsatellite instability, especially characteristics of primary multiple colorectal cancers.
Author: Abe, Y|Masuda, H
PMID: 10962455
Journal: Gastroenterol Clin Biol. 2000 Oct;24(10):917-22.
Title: [Response of metastatic colorectal cancers to treatment with CPT11 (irinotecan): implications of the mismatched base repair system].
Author: Fallik, D|Sabourin, J C|Borrini, F|Jacob, S|Boige, V|Praz, F|Ducreux, M
PMID: 11084429
Journal: Comb Chem High Throughput Screen. 2000 Dec;3(6):519-24.
Title: High throughput genetic screening for the detection of hereditary non-polyposis colon cancer (HNPCC) using capillary electrophoresis.
Author: Merkelbach-Bruse, S|Kose, S|Losen, I|Bosserhoff, A K|Buettner, R
PMID: 11121520
Journal: Hum Mol Genet. 2001 Mar 1;10(5):513-8.
Title: Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers.
Author: Duval, A|Rolland, S|Compoint, A|Tubacher, E|Iacopetta, B|Thomas, G|Hamelin, R
PMID: 11181575
Journal: Cancer Res. 2001 Feb 15;61(4):1619-23.
Title: MSH6 and MSH3 are rarely involved in genetic predisposition to nonpolypotic colon cancer.
Author: Huang, J|Kuismanen, S A|Liu, T|Chadwick, R B|Johnson, C K|Stevens, M W|Richards, S K|Meek, J E|Gao, X|Wright, F A|Mecklin, J P|Jarvinen, H J|Gronberg, H|Bisgaard, M L|Lindblom, A|Peltomaki, P
PMID: 11245474
Journal: Am J Pathol. 2001 Apr;158(4):1517-24.
Title: Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer.
Author: Samowitz, W S|Holden, J A|Curtin, K|Edwards, S L|Walker, A R|Lin, H A|Robertson, M A|Nichols, M F|Gruenthal, K M|Lynch, B J|Leppert, M F|Slattery, M L
PMID: 11290569
Journal: Jpn J Clin Oncol. 2001 Feb;31(2):61-4.
Title: Infrequent frameshift mutations in the simple repeat sequences of hMLH3 in hereditary nonpolyposis colorectal cancers.
Author: Akiyama, Y|Nagasaki, H|Nakajima, T|Sakai, H|Nomizu, T|Yuasa, Y
PMID: 11302343
Journal: Gene. 2001 Jul 11;272(1-2):301-13.
Title: Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype.
Author: Ohmiya, N|Matsumoto, S|Yamamoto, H|Baranovskaya, S|Malkhosyan, S R|Perucho, M
PMID: 11470537
Journal: Oncogene. 2001 Aug 2;20(34):4640-9.
Title: Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.
Author: Wang, Q|Zhang, H|Guerrette, S|Chen, J|Mazurek, A|Wilson, T|Slupianek, A|Skorski, T|Fishel, R|Greene, M I
PMID: 11498787
Journal: Dig Dis Sci. 2001 Aug;46(8):1615-22.
Title: Relationship between grade of microsatellite instability and target genes of mismatch repair pathways in sporadic colorectal carcinoma.
Author: Togo, G|Shiratori, Y|Okamoto, M|Yamaji, Y|Matsumura, M|Sano, T|Motojima, T|Omata, M
PMID: 11508658
Journal: Cancer Lett. 2001 Dec 28;174(2):189-94.
Title: PTEN gene mutations in colorectal cancers displaying microsatellite instability.
Author: Shin, K H|Park, Y J|Park, J G
PMID: 11689295
Journal: Cancer Invest. 2002;20(1):102-9.
Title: Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC).
Author: Muller, Annegret|Fishel, Richard
PMID: 11852992
Journal: Cancer Genet Cytogenet. 2002 Apr 1;134(1):46-54.
Title: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
Author: Planck, Maria|Halvarsson, Britta|Palsson, Eva|Hallen, Magnus|Ekelund, Mats|Palsson, Birger|Baldetorp, Bo|Nilbert, Mef
PMID: 11996796
Journal: Hum Mol Genet. 2002 May 15;11(11):1303-10.
Title: Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome.
Author: Kariola, Reetta|Raevaara, Tiina E|Lonnqvist, Karin E|Nystrom-Lahti, Minna
PMID: 12019211
Journal: Mutat Res. 2002 Jun 19;503(1-2):37-42.
Title: A hMLH1 genomic mutation and associated novel mRNA defects in a hereditary non-polyposis colorectal cancer family.
Author: Tanko, Q|Franklin, B|Lynch, H|Knezetic, J
PMID: 12052501
Journal: Am J Pathol. 2002 Jun;160(6):1953-8.
Title: Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
Author: Kuismanen, Shannon A|Moisio, Anu-Liisa|Schweizer, Pascal|Truninger, Kaspar|Salovaara, Reijo|Arola, Johanna|Butzow, Ralf|Jiricny, Josef|Nystrom-Lahti, Minna|Peltomaki, Paivi
PMID: 12057899
Journal: Biochem Pharmacol. 2002 Oct 15;64(8):1267-77.
Title: The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer.
Author: van Hattum, Annemarie H|Pinedo, Herbert M|Schluper, Hennie M M|Erkelens, Caroline A M|Tohgo, Akiko|Boven, Epie
PMID: 12234607
Journal: Leuk Lymphoma. 2002 Aug;43(8):1619-26.
Title: Analysis of mismatch repair defects in the familial occurrence of lymphoma and colorectal cancer.
Author: Teruya-Feldstein, J|Greene, J|Cohen, L|Popplewell, L|Ellis, Nathan A|Offit, K
PMID: 12400605
Journal: Cancer Res. 2002 Dec 1;62(23):6796-802.
Title: Frequent microsatellite instability in sporadic tumors of the upper urinary tract.
Author: Hartmann, Arndt|Zanardo, Livia|Bocker-Edmonston, Tina|Blaszyk, Hagen|Dietmaier, Wolfgang|Stoehr, Robert|Cheville, John C|Junker, Kerstin|Wieland, Wolf|Knuechel, Ruth|Rueschoff, Josef|Hofstaedter, Ferdinand|Fishel, Richard
PMID: 12460887
Journal: Int J Oncol. 2003 Jan;22(1):41-9.
Title: Combined deficiency of hMLH1, hMSH2, hMSH3 and hMSH6 is an independent prognostic factor in colorectal cancer.
Author: Jansson, Agneta|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 12469183
Journal: Clin Chem. 2003 Apr;49(4):552-61.
Title: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based detection of microsatellite instabilities in coding DNA sequences: a novel approach to identify DNA-mismatch repair-deficient cancer cells.
Author: Bonk, Thomas|Humeny, Andreas|Gebert, Johannes|Sutter, Christian|von Knebel Doeberitz, Magnus|Becker, Cord-Michael
PMID: 12651806
Journal: Int J Cancer. 2003 Jul 1;105(4):484-90.
Title: Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability.
Author: Catto, James W F|Xinarianos, George|Burton, Julian L|Meuth, Mark|Hamdy, Freddie C
PMID: 12712438
Journal: Oncol Rep. 2003 Jul-Aug;10(4):859-66.
Title: Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene.
Author: Yamada, Kanae|Zhong, Xiaoling|Kanazawa, Shinsaku|Koike, Junichi|Tsujita, Kazunori|Hemmi, Hiromichi
PMID: 12792735
Journal: Dis Colon Rectum. 2003 Aug;46(8):1069-77.
Title: Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers.
Author: Jeong, Seung-Yong|Shin, Ki-Hyuk|Shin, Joo-Ho|Ku, Ja-Lok|Shin, Young-Kyoung|Park, So-Yeon|Kim, Woo-Ho|Park, Jae-Gahb
PMID: 12907901
Journal: Cancer Res. 2003 Sep 15;63(18):5738-44.
Title: Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer.
Author: Fallik, David|Borrini, Francesco|Boige, Valerie|Viguier, Jerome|Jacob, Sandrine|Miquel, Catherine|Sabourin, Jean-Christophe|Ducreux, Michel|Praz, Francoise
PMID: 14522894
Journal: J Gastroenterol. 2003;38(12):1185-8.
Title: Genetic analysis of radiation-associated rectal cancer.
Author: Tsuji, Takashi|Sawai, Terumitsu|Nakagoe, Tohru|Hidaka, Shigekazu|Shibasaki, Shinichi|Tanaka, Kenji|Nanashima, Atsushi|Yamaguchi, Hiroyuki|Yasutake, Tohru|Tagawa, Yutaka
PMID: 14714259
Journal: Cancer Res. 2004 Feb 1;64(3):864-70.
Title: Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.
Author: Plaschke, Jens|Kruger, Stefan|Jeske, Birgit|Theissig, Franz|Kreuz, Friedmar R|Pistorius, Steffen|Saeger, Hans D|Iaccarino, Ingram|Marra, Giancarlo|Schackert, Hans K
PMID: 14871813
Journal: Zhonghua Bing Li Xue Za Zhi. 2004 Feb;33(1):6-10.
Title: [Transforming growth factor beta receptor II mutations in RER positive colorectal cancers].
Author: Lai, Mao-de|Huang, Zhi-da|Huang, Qiong|Chen, Jian
PMID: 14989920
Journal: Cancer Genet Cytogenet. 2004 Sep;153(2):108-14.
Title: Multiple epithelial and nonepithelial tumors in hereditary nonpolyposis colorectal cancer: characterization of germline and somatic mutations of the MSH2 gene and heterogeneity of replication error phenotypes.
Author: Huang, Rui-Len|Chao, Chung-Faye|Ding, Dah-Ching|Yu, Cheng-Ping|Chang, Cheng-Chang|Lai, Hung-Chen|Yu, Mu-Hsien|Liu, Hang-Seng|Chu, Tang-Yuan
PMID: 15350299
Journal: Hum Mol Genet. 2005 Aug 15;14(16):2435-42. Epub 2005 Jul 6.
Title: Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers.
Author: El-Bchiri, Jamila|Buhard, Olivier|Penard-Lacronique, Virginie|Thomas, Gilles|Hamelin, Richard|Duval, Alex
PMID: 16000315
Journal: Oncogene. 2006 Mar 16;25(12):1743-52.
Title: The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1.
Author: Abdul-Ghani, R|Serra, V|Gyorffy, B|Jurchott, K|Solf, A|Dietel, M|Schafer, R
PMID: 16288223
Journal: Dis Colon Rectum. 2006 Mar;49(3):399-406.
Title: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer.
Author: Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko
PMID: 16421660
Journal: Int J Cancer. 2007 Apr 1;120(7):1548-54.
Title: Mismatch repair polymorphisms and the risk of colorectal cancer.
Author: Berndt, Sonja I|Platz, Elizabeth A|Fallin, M Daniele|Thuita, Lucy W|Hoffman, Sandra C|Helzlsouer, Kathy J
PMID: 17205513
Journal: Gut. 2008 Aug;57(8):1097-101.
Title: Common variants in mismatch repair genes and risk of colorectal cancer.
Author: Koessler, T|Oestergaard, M Z|Song, H|Tyrer, J|Perkins, B|Dunning, A M|Easton, D F|Pharoah, P D P
PMID: 18364438
Journal: Cancer Res. 2008 Oct 15;68(20):8465-72.
Title: Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.
Author: Haugen, Astrid C|Goel, Ajay|Yamada, Kanae|Marra, Giancarlo|Nguyen, Thuy-Phuong|Nagasaka, Takeshi|Kanazawa, Shinsaku|Koike, Junichi|Kikuchi, Yoshinori|Zhong, Xiaoling|Arita, Michitsune|Shibuya, Kazutoshi|Oshimura, Mitsuo|Hemmi, Hiromichi|Boland, C Richard|
PMID: 18922920
Journal: Int J Cancer. 2009 Apr 15;124(8):1887-91.
Title: Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.
Author: Koessler, Thibaud|Azzato, Elizabeth M|Perkins, Barbara|Macinnis, Robert J|Greenberg, David|Easton, Douglas F|Pharoah, Paul D P
PMID: 19115210
Journal: Int J Oncol. 2009 Nov;35(5):977-82.
Title: Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.
Author: Kawaguchi, Makiko|Banno, Kouji|Yanokura, Megumi|Kobayashi, Yusuke|Kishimi, Arisa|Ogawa, Seiji|Kisu, Iori|Nomura, Hiroyuki|Hirasawa, Akira|Susumu, Nobuyuki|Aoki, Daisuke
PMID: 19787250
Journal: BMC Cancer. 2010 Jun 18;10:303.
Title: Mutations in TGFbeta-RII and BAX mediate tumor progression in the later stages of colorectal cancer with microsatellite instability.
Author: Yashiro, Masakazu|Hirakawa, Kosei|Boland, C Richard
PMID: 20565851
Journal: J Gastrointestin Liver Dis. 2010 Jun;19(2):155-9.
Title: MMR gene expression pattern in sporadic colorectal cancer.
Author: Ioana, Mihai|Angelescu, Cristina|Burada, Florin|Mixich, Francisc|Riza, Anca|Dumitrescu, Theodor|Alexandru, Dragos|Ciurea, Tudorel|Cruce, Mihai|Saftoiu, Adrian
PMID: 20593048
Journal: Gastroenterology. 2010 Nov;139(5):1519-25.
Title: Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias.
Author: Lee, Sun-Young|Chung, Heekyung|Devaraj, Bikash|Iwaizumi, Moriya|Han, Hye Seung|Hwang, Dae-Yong|Seong, Moo Kyung|Jung, Barbara H|Carethers, John M
PMID: 20708618
Journal: J Gastrointest Surg. 2010 Oct;14(10):1521-8.
Title: Relationship of EMAST and microsatellite instability among patients with rectal cancer.
Author: Devaraj, Bikash|Lee, Aaron|Cabrera, Betty L|Miyai, Katsumi|Luo, Linda|Ramamoorthy, Sonia|Keku, Temitope|Sandler, Robert S|McGuire, Kathleen L|Carethers, John M
PMID: 20844976
Journal: BMC Cancer. 2010 Oct 27;10:587.
Title: Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
Author: Pinheiro, Manuela|Ahlquist, Terje|Danielsen, Stine A|Lind, Guro E|Veiga, Isabel|Pinto, Carla|Costa, Vera|Afonso, Luis|Sousa, Olga|Fragoso, Maria|Santos, Lucio|Henrique, Rui|Lopes, Paula|Lopes, Carlos|Lothe, Ragnhild A|Teixeira, Manuel R
PMID: 20979647
Journal: PLoS One. 2010 Dec 31;5(12):e16012.
Title: Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability.
Author: Williams, David S|Bird, Matthew J|Jorissen, Robert N|Yu, Yen Lin|Walker, Francesca|Zhang, Hui Hua|Nice, Edouard C|Burgess, Antony W
PMID: 21209843
Journal: Cancer. 2011 Feb 1;117(3):492-500.
Title: Evidence for an hMSH3 defect in familial hamartomatous polyps.
Author: Huang, Sherry C|Lee, Jeffrey K|Smith, E Julieta|Doctolero, Ryan T|Tajima, Akihiro|Beck, Stayce E|Weidner, Noel|Carethers, John M
PMID: 20845481
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Title: Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.
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Journal: J Biol Chem. 2011 Apr 8;286(14):12157-65.
Title: MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor.
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Journal: J Mol Biol. 2011 Aug 26;411(4):765-80.
Title: Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I.
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Title: An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopes.
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Title: Alterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancer.
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Title: Candidate driver genes in microsatellite-unstable colorectal cancer.
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Title: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.
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Title: Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability.
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Journal: Biochim Biophys Acta. 2012 Apr;1823(4):889-99.
Title: Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer.
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Title: Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells.
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Journal: Cancer Chemother Pharmacol. 2013 Jul;72(1):117-25.
Title: MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.
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Journal: Mutat Res. 2013 Jul-Aug;747-748:19-27.
Title: Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.
Author: Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Carethers, John M
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Journal: PLoS One. 2013 May 28;8(5):e65369.
Title: MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
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Title: Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
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Journal: Gynecol Oncol. 2014 Feb;132(2):506-12.
Title: Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications.
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Title: Molecular characteristics of mismatch repair genes in sporadic colorectal tumors in Czech patients.
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Title: Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
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Journal: Int J Cancer. 2015 Mar 15;136(6):E559-68.
Title: Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.
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Journal: Gastroenterology. 2015 Mar;148(3):579-89.
Title: Interleukin 6 alters localization of hMSH3, leading to DNA mismatch repair defects in colorectal cancer cells.
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Journal: Genes Nutr. 2015 Jan;10(1):448.
Title: Interactions between meat intake and genetic variation in relation to colorectal cancer.
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Journal: Arch Toxicol. 2015 Jun;89(6):899-921.
Title: Microsatellite instability: an update.
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Journal: Genes (Basel). 2015 Mar 31;6(2):185-205.
Title: EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression.
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Journal: PLoS One. 2015 Apr 17;10(4):e0124538.
Title: EMAST is associated with a poor prognosis in microsatellite instable metastatic colorectal cancer.
Author: Venderbosch, Sabine|van Lent-van Vliet, Shannon|de Haan, Anton F J|Ligtenberg, Marjolijn J|Goossens, Monique|Punt, Cornelis J A|Koopman, Miriam|Nagtegaal, Iris D
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Journal: Cell. 2015 May 7;161(4):933-45.
Title: Prospective derivation of a living organoid biobank of colorectal cancer patients.
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Journal: PLoS One. 2015 May 21;10(5):e0127591.
Title: Efficacy of Adjuvant 5-Fluorouracil Therapy for Patients with EMAST-Positive Stage II/III Colorectal Cancer.
Author: Hamaya, Yasushi|Guarinos, Carla|Tseng-Rogenski, Stephanie S|Iwaizumi, Moriya|Das, Ritabrata|Jover, Rodrigo|Castells, Antoni|Llor, Xavier|Andreu, Montserrat|Carethers, John M
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Journal: Br J Cancer. 2015 Aug 11;113(4):686-92.
Title: Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.
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Journal: Int J Clin Exp Pathol. 2015 Sep 1;8(9):11060-7. eCollection 2015.
Title: MSH3 rs26279 polymorphism increases cancer risk: a meta-analysis.
Author: Miao, Hui-Kai|Chen, Li-Ping|Cai, Dong-Ping|Kong, Wei-Ju|Xiao, Li|Lin, Jie
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Journal: Int J Cancer. 2016 Apr 1;138(7):1634-44.
Title: Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway.
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Journal: Gastroenterology. 2016 Apr;150(4):944-55.
Title: Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.
Author: Koi, Minoru|Garcia, Melissa|Choi, Chan|Kim, Hyeong-Rok|Koike, Junichi|Hemmi, Hiromichi|Nagasaka, Takeshi|Okugawa, Yoshinaga|Toiyama, Yuji|Kitajima, Takahito|Imaoka, Hiroki|Kusunoki, Masato|Chen, Yin-Hsiu|Mukherjee, Bhramar|Boland, C Richard|Carethers, Joh
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Journal: Int J Mol Med. 2016 Sep;38(3):687-702.
Title: Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.
Author: Silva, Patricia|Albuquerque, Cristina|Lage, Pedro|Fontes, Vanessa|Fonseca, Ricardo|Vitoriano, Ines|Filipe, Bruno|Rodrigues, Paula|Moita, Susana|Ferreira, Sara|Sousa, Rita|Claro, Isabel|Nobre Leitao, Carlos|Chaves, Paula|Dias Pereira, Antonio
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Journal: Am J Hum Genet. 2016 Aug 4;99(2):337-51.
Title: Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
Author: Adam, Ronja|Spier, Isabel|Zhao, Bixiao|Kloth, Michael|Marquez, Jonathan|Hinrichsen, Inga|Kirfel, Jutta|Tafazzoli, Aylar|Horpaopan, Sukanya|Uhlhaas, Siegfried|Stienen, Dietlinde|Friedrichs, Nicolaus|Altmuller, Janine|Laner, Andreas|Holzapfel, Stefanie|Pete
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Journal: Curr Mol Med. 2016;16(9):829-839.
Title: Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.
Author: Lee, H S|Park, K U|Kim, D-W|Lhn, M H|Kim, W H|Seo, A N|Chang, H E|Nam, S K|Lee, S Y|Oh, H-K|Kang, S-B
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Journal: Trans Am Clin Climatol Assoc. 2016;127:81-97.
Title: HEREDITARY, SPORADIC AND METASTATIC COLORECTAL CANCER ARE COMMONLY DRIVEN BY SPECIFIC SPECTRUMS OF DEFECTIVE DNA MISMATCH REPAIR COMPONENTS.
Author: Carethers, John M
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Journal: Fam Cancer. 2017 Apr;16(2):195-203.
Title: Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing.
Author: Rohlin, Anna|Rambech, Eva|Kvist, Anders|Torngren, Therese|Eiengard, Frida|Lundstam, Ulf|Zagoras, Theofanis|Gebre-Medhin, Samuel|Borg, Ake|Bjork, Jan|Nilbert, Mef|Nordling, Margareta
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Journal: Oncotarget. 2017 Jan 31;8(5):7852-7866.
Title: Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Author: Ashktorab, Hassan|Mokarram, Pooneh|Azimi, Hamed|Olumi, Hasti|Varma, Sudhir|Nickerson, Michael L|Brim, Hassan
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Journal: Mol Carcinog. 2017 Jul;56(7):1816-1824.
Title: Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.
Author: Hinrichsen, Inga|Ackermann, Anne|Duding, Tonja|Graband, Annika|Filmann, Natalie|Plotz, Guido|Zeuzem, Stefan|Brieger, Angela
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Journal: G3 (Bethesda). 2017 May 5;7(5):1463-1473.
Title: Schizosaccharomyces pombe MutSalpha and MutLalpha Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats.
Author: Villahermosa, Desiree|Christensen, Olaf|Knapp, Karen|Fleck, Oliver
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Journal: Fam Cancer. 2017 Oct;16(4):491-500.
Title: Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6.
Author: Morak, Monika|Kasbauer, Sarah|Kerscher, Martina|Laner, Andreas|Nissen, Anke M|Benet-Pages, Anna|Schackert, Hans K|Keller, Gisela|Massdorf, Trisari|Holinski-Feder, Elke
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Journal: J BUON. 2017 May-Jun;22(3):606-609.
Title: DNA mismatch repair deficiency in lung and oral cavity carcinomas: the role of histogenetic origin.
Author: Spetsotaki, Konstantina N|Tsiambas, Evangelos|Stamatelopoulos, Athanasios|Fotiades, Panagiotis P|Kastanioudakis, Ioannis|Tomos, Pericles|Ragos, Vasileios
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Journal: Oncotarget. 2017 Jun 21;8(55):93450-93463.
Title: Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort.
Author: Raskin, Leon|Guo, Yan|Du, Liping|Clendenning, Mark|Rosty, Christophe|Lindor, Noralane M|Gruber, Stephen B|Buchanan, Daniel D
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Journal: Oncotarget. 2017 Oct 7;8(59):99966-99977.
Title: Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia.
Author: Ashktorab, Hassan|Azimi, Hamed|Varma, Sudhir|Tavakoli, Payaam|Nickerson, Michael L|Brim, Hassan
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Journal: World J Gastrointest Oncol. 2018 Jan 15;10(1):1-14.
Title: Inflammation-associated microsatellite alterations: Mechanisms and significance in the prognosis of patients with colorectal cancer.
Author: Koi, Minoru|Tseng-Rogenski, Stephanie S|Carethers, John M
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Journal: Mol Med Rep. 2018 May;17(5):6942-6946.
Title: Novel MSH2 splice-site mutation in a young patient with Lynch syndrome.
Author: Liccardo, Raffaella|De Rosa, Marina|Izzo, Paola|Duraturo, Francesca
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Journal: J Anus Rectum Colon. 2018;2(2):37-46.
Title: Fusobacterium nucleatum Infection in Colorectal Cancer: Linking Inflammation, DNA Mismatch Repair and Genetic and Epigenetic Alterations.
Author: Koi, Minoru|Okita, Yoshiki|Carethers, John M
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