Primary Site >> Colorectal Cancer
Gene >> MRE11
| 1. | |||||||||||
| Journal: | Oncogene. 1999 Jun 3;18(22):3422-6. | ||||||||||
| Title: | Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. | ||||||||||
| Author: | Hiramoto, T|Nakanishi, T|Sumiyoshi, T|Fukuda, T|Matsuura, S|Tauchi, H|Komatsu, K|Shibasaki, Y|Inui, H|Watatani, M|Yasutomi, M|Sumii, K|Kajiyama, G|Kamada, N|Miyagawa, K|Kamiya, K | ||||||||||
| PMID: | 10362364 | ||||||||||
| 2. | |||||||||||
| Journal: | EMBO Rep. 2002 Mar;3(3):248-54. Epub 2002 Feb 15. | ||||||||||
| Title: | Human MRE11 is inactivated in mismatch repair-deficient cancers. | ||||||||||
| Author: | Giannini, Giuseppe|Ristori, Elisabetta|Cerignoli, Fabio|Rinaldi, Christian|Zani, Massimo|Viel, Alessandra|Ottini, Laura|Crescenzi, Marco|Martinotti, Stefano|Bignami, Margherita|Frati, Luigi|Screpanti, Isabella|Gulino, Alberto | ||||||||||
| PMID: | 11850399 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2003 Apr 10;22(14):2110-20. | ||||||||||
| Title: | The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase. | ||||||||||
| Author: | Franchitto, Annapaola|Pichierri, Pietro|Piergentili, Rita|Crescenzi, Marco|Bignami, Margherita|Palitti, Fabrizio | ||||||||||
| PMID: | 12687013 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2004 Apr 8;23(15):2640-7. | ||||||||||
| Title: | Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. | ||||||||||
| Author: | Giannini, Giuseppe|Rinaldi, Christian|Ristori, Elisabetta|Ambrosini, Maria Irene|Cerignoli, Fabio|Viel, Alessandra|Bidoli, Ettore|Berni, Silvia|D'Amati, Giulia|Scambia, Giovanni|Frati, Luigi|Screpanti, Isabella|Gulino, Alberto | ||||||||||
| PMID: | 15048091 | ||||||||||
| 5. | |||||||||||
| Journal: | World J Gastroenterol. 2005 Sep 7;11(33):5156-61. | ||||||||||
| Title: | Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cells. | ||||||||||
| Author: | Park, Hae-Jeong|Yoon, Seo-Hyun|Han, Long-Shan|Zheng, Long-Tai|Jung, Kyung-Hee|Uhm, Yoon-Kyung|Lee, Je-Hyun|Jeong, Ji-Seon|Joo, Woo-Sang|Yim, Sung-Vin|Chung, Joo-Ho|Hong, Seon-Pyo | ||||||||||
| PMID: | 16127745 | ||||||||||
| 6. | |||||||||||
| Journal: | J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10. | ||||||||||
| Title: | Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks. | ||||||||||
| Author: | Takemura, Haruyuki|Rao, V Ashutosh|Sordet, Olivier|Furuta, Takahisa|Miao, Ze-Hong|Meng, Linghua|Zhang, Hongliang|Pommier, Yves | ||||||||||
| PMID: | 16905549 | ||||||||||
| 7. | |||||||||||
| Journal: | Eur J Hum Genet. 2007 Sep;15(9):922-9. Epub 2007 May 30. | ||||||||||
| Title: | The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients. | ||||||||||
| Author: | Alemayehu, Aster|Fridrichova, Ivana | ||||||||||
| PMID: | 17534377 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 2007 Dec 1;67(23):11158-65. | ||||||||||
| Title: | Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. | ||||||||||
| Author: | Ebi, Hiromichi|Matsuo, Keitaro|Sugito, Nobuyoshi|Suzuki, Motoshi|Osada, Hirotaka|Tajima, Kazuo|Ueda, Ryuzo|Takahashi, Takashi | ||||||||||
| PMID: | 18056440 | ||||||||||
| 9. | |||||||||||
| Journal: | Mutat Res. 2008 Sep-Oct;659(3):262-73. | ||||||||||
| Title: | The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer. | ||||||||||
| Author: | Dzikiewicz-Krawczyk, Agnieszka | ||||||||||
| PMID: | 18606567 | ||||||||||
| 10. | |||||||||||
| Journal: | Br J Cancer. 2008 Nov 18;99(10):1607-12. | ||||||||||
| Title: | Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. | ||||||||||
| Author: | Vilar, E|Scaltriti, M|Balmana, J|Saura, C|Guzman, M|Arribas, J|Baselga, J|Tabernero, J | ||||||||||
| PMID: | 18941461 | ||||||||||
| 11. | |||||||||||
| Journal: | Histol Histopathol. 2008 Dec;23(12):1495-502. | ||||||||||
| Title: | RAD50/MRE11/NBS1 proteins in relation to tumour development and prognosis in patients with microsatellite stable colorectal cancer. | ||||||||||
| Author: | Gao, Jingfang|Zhang, Hong|Arbman, Gunnar|Sun, Xiao-Feng | ||||||||||
| PMID: | 18830935 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Sep 1;14(17):5476-83. | ||||||||||
| Title: | Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11. | ||||||||||
| Author: | Rodriguez, Rene|Hansen, Lasse Tengbjerg|Phear, Geraldine|Scorah, Jennifer|Spang-Thomsen, Mogens|Cox, Angela|Helleday, Thomas|Meuth, Mark | ||||||||||
| PMID: | 18765539 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Biol Cell. 2008 Apr;19(4):1693-705. | ||||||||||
| Title: | A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner. | ||||||||||
| Author: | Wen, Qin|Scorah, Jennifer|Phear, Geraldine|Rodgers, Gary|Rodgers, Sheila|Meuth, Mark | ||||||||||
| PMID: | 18256278 | ||||||||||
| 14. | |||||||||||
| Journal: | Orv Hetil. 2009 Aug 23;150(34):1607-13. | ||||||||||
| Title: | [Tissue microarray (TMA) validated progression markers in colorectal cancer using antibody microarrays]. | ||||||||||
| Author: | Spisak, Sandor|Galamb, Barnabas|Wichmann, Barnabas|Sipos, Ferenc|Galamb, Orsolya|Solymosi, Norbert|Nemes, Balazs|Tulassay, Zsolt|Molnar, Bela | ||||||||||
| PMID: | 19648079 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Mol Epidemiol Genet. 2012;3(3):184-94. Epub 2012 Aug 31. | ||||||||||
| Title: | Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. | ||||||||||
| Author: | Pellatt, Andrew J|Wolff, Roger K|Lundgreen, Abbie|Cawthon, Richard|Slattery, Martha L | ||||||||||
| PMID: | 23050049 | ||||||||||
| 16. | |||||||||||
| Journal: | G3 (Bethesda). 2013 Feb;3(2):273-82. | ||||||||||
| Title: | Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. | ||||||||||
| Author: | van Pel, Derek M|Stirling, Peter C|Minaker, Sean W|Sipahimalani, Payal|Hieter, Philip | ||||||||||
| PMID: | 23390603 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Biol Rep. 2013 Nov;40(11):6351-61. | ||||||||||
| Title: | Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue. | ||||||||||
| Author: | Storcelova, Maria|Vician, Marian|Reis, Richard|Zeman, Michal|Herichova, Iveta | ||||||||||
| PMID: | 24062075 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2013 Sep 9;8(9):e73593. | ||||||||||
| Title: | Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. | ||||||||||
| Author: | Birkenkamp-Demtroder, Karin|Hahn, Stephan A|Mansilla, Francisco|Thorsen, Kasper|Maghnouj, Abdelouahid|Christensen, Rikke|Oster, Bodil|Orntoft, Torben Falck | ||||||||||
| PMID: | 24039993 | ||||||||||
| 19. | |||||||||||
| Journal: | Tumour Biol. 2013 Aug;34(4):2141-6. | ||||||||||
| Title: | Clinicopathological significance of BTF3 expression in colorectal cancer. | ||||||||||
| Author: | Wang, Chao-Jie|Franbergh-Karlson, Hanna|Wang, Da-Wei|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng | ||||||||||
| PMID: | 23532689 | ||||||||||
| 20. | |||||||||||
| Journal: | J Gastrointest Cancer. 2013 Mar;44(1):41-5. | ||||||||||
| Title: | Effects of radiation on levels of DNA damage in normal non-adjacent mucosa from colorectal cancer cases. | ||||||||||
| Author: | Sheridan, Juliette|Tosetto, Miriam|Gorman, Julie|O'Donoghue, Diarmuid|Sheahan, Kieran|Hyland, John|Mulcahy, Hugh|Gibbons, David|O'Sullivan, Jacintha | ||||||||||
| PMID: | 23065707 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Lett. 2014 Feb 28;343(2):217-23. | ||||||||||
| Title: | Poly (ADP-ribose) polymerase inhibitor LT-626: Sensitivity correlates with MRE11 mutations and synergizes with platinums and irinotecan in colorectal cancer cells. | ||||||||||
| Author: | McPherson, Lisa A|Shen, Yuqiao|Ford, James M | ||||||||||
| PMID: | 24215868 | ||||||||||
| 22. | |||||||||||
| Journal: | Tumour Biol. 2014 Apr;35(4):3525-34. | ||||||||||
| Title: | The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. | ||||||||||
| Author: | Sahlberg, Sara Haggblad|Gustafsson, Ann-Sofie|Pendekanti, Prathyusha N|Glimelius, Bengt|Stenerlow, Bo | ||||||||||
| PMID: | 24338765 | ||||||||||
| 23. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 May;13(5):1170-80. | ||||||||||
| Title: | The use of Olaparib (AZD2281) potentiates SN-38 cytotoxicity in colon cancer cells by indirect inhibition of Rad51-mediated repair of DNA double-strand breaks. | ||||||||||
| Author: | Tahara, Makiko|Inoue, Takeshi|Sato, Futoshi|Miyakura, Yasuyuki|Horie, Hisanaga|Yasuda, Yoshikazu|Fujii, Hirofumi|Kotake, Kenjiro|Sugano, Kokichi | ||||||||||
| PMID: | 24577941 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2014 Oct 13;9(10):e108483. | ||||||||||
| Title: | MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. | ||||||||||
| Author: | Pavelitz, Thomas|Renfro, Lindsay|Foster, Nathan R|Caracol, Amber|Welsch, Piri|Lao, Victoria Valinluck|Grady, William B|Niedzwiecki, Donna|Saltz, Leonard B|Bertagnolli, Monica M|Goldberg, Richard M|Rabinovitch, Peter S|Emond, Mary|Monnat, Raymond J Jr|Maiz | ||||||||||
| PMID: | 25310185 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Cell Int. 2015 Feb 4;15(1):14. | ||||||||||
| Title: | Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status. | ||||||||||
| Author: | Genther Williams, Sybil M|Kuznicki, Apryle M|Andrade, Paula|Dolinski, Brian M|Elbi, Cem|O'Hagan, Ronan C|Toniatti, Carlo | ||||||||||
| PMID: | 25685067 | ||||||||||
| 26. | |||||||||||
| Journal: | Arch Toxicol. 2015 Jun;89(6):899-921. | ||||||||||
| Title: | Microsatellite instability: an update. | ||||||||||
| Author: | Yamamoto, Hiroyuki|Imai, Kohzoh | ||||||||||
| PMID: | 25701956 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncol Rep. 2016 Mar;35(3):1349-55. | ||||||||||
| Title: | Expression of DNA double-strand break repair proteins predicts the response and prognosis of colorectal cancer patients undergoing oxaliplatin-based chemotherapy. | ||||||||||
| Author: | Ihara, Keisuke|Yamaguchi, Satoru|Ueno, Nozomi|Tani, Yukiko|Shida, Yosuke|Ogata, Hideo|Domeki, Yasushi|Okamoto, Kentaro|Nakajima, Masanobu|Sasaki, Kinro|Tsuchioka, Takashi|Mitomi, Hiroyuki|Kato, Hiroyuki | ||||||||||
| PMID: | 26676960 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 26;7(17):23156-69. | ||||||||||
| Title: | Double-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcome. | ||||||||||
| Author: | Naccarati, Alessio|Rosa, Fabio|Vymetalkova, Veronika|Barone, Elisa|Jiraskova, Katerina|Di Gaetano, Cornelia|Novotny, Jan|Levy, Miroslav|Vodickova, Ludmila|Gemignani, Federica|Buchler, Tomas|Landi, Stefano|Vodicka, Pavel|Pardini, Barbara | ||||||||||
| PMID: | 26735576 | ||||||||||
| 29. | |||||||||||
| Journal: | Nat Commun. 2016 Jun 22;7:11883. | ||||||||||
| Title: | Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. | ||||||||||
| Author: | Chubb, Daniel|Broderick, Peter|Dobbins, Sara E|Frampton, Matthew|Kinnersley, Ben|Penegar, Steven|Price, Amy|Ma, Yussanne P|Sherborne, Amy L|Palles, Claire|Timofeeva, Maria N|Bishop, D Timothy|Dunlop, Malcolm G|Tomlinson, Ian|Houlston, Richard S | ||||||||||
| PMID: | 27329137 | ||||||||||
| 30. | |||||||||||
| Journal: | PLoS One. 2016 Dec 8;11(12):e0167675. | ||||||||||
| Title: | MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response. | ||||||||||
| Author: | Ho, Vincent|Chung, Liping|Revoltar, Maxine|Lim, Stephanie H|Tut, Thein-Ga|Abubakar, Askar|Henderson, Chris J|Chua, Wei|Ng, Weng|Lee, Mark|De Souza, Paul|Morgan, Matthew|Lee, C Soon|Shin, Joo-Shik | ||||||||||
| PMID: | 27930716 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncogene. 2018 Jan 25;37(4):427-438. | ||||||||||
| Title: | AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11. | ||||||||||
| Author: | Piscitello, D|Varshney, D|Lilla, S|Vizioli, M G|Reid, C|Gorbunova, V|Seluanov, A|Gillespie, D A|Adams, P D | ||||||||||
| PMID: | 28967905 | ||||||||||
| 32. | |||||||||||
| Journal: | Neoplasma. 2018;65(1):75-80. | ||||||||||
| Title: | Targeting RAD50 increases sensitivity to radiotherapy in colorectal cancer cells. | ||||||||||
| Author: | Chen, C|Wang, Y|Mei, J F|Li, S S|Xu, H X|Xiong, H P|Wang, X H|He, X | ||||||||||
| PMID: | 29322791 | ||||||||||
| 33. | |||||||||||
| Journal: | BMC Cancer. 2018 Sep 3;18(1):869. | ||||||||||
| Title: | Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis. | ||||||||||
| Author: | Ho, Vincent|Chung, Liping|Singh, Amandeep|Lea, Vivienne|Abubakar, Askar|Lim, Stephanie H|Ng, Weng|Lee, Mark|de Souza, Paul|Shin, Joo-Shik|Lee, Cheok Soon | ||||||||||
| PMID: | 30176843 | ||||||||||