Primary Site >> Colorectal Cancer

Gene >> MLH1

Journal: Cancer. 1985 Aug 15;56(4):939-51.
Title: Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). II. Biomarker studies.
Author: Lynch, H T|Schuelke, G S|Kimberling, W J|Albano, W A|Lynch, J F|Biscone, K A|Lipkin, M L|Deschner, E E|Mikol, Y B|Sandberg, A A
PMID: 4016686
Journal: Ann Surg. 1987 Sep;206(3):289-95.
Title: Recognition and treatment of patients with hereditary nonpolyposis colon cancer (Lynch syndromes I and II).
Author: Fitzgibbons, R J Jr|Lynch, H T|Stanislav, G V|Watson, P A|Lanspa, S J|Marcus, J N|Smyrk, T|Kriegler, M D|Lynch, J F
PMID: 3632093
Journal: Gastroenterol Clin North Am. 1988 Dec;17(4):679-712.
Title: Hereditary nonpolyposis colorectal cancer--Lynch syndromes I and II.
Author: Lynch, H T|Lanspa, S J|Boman, B M|Smyrk, T|Watson, P|Lynch, J F|Lynch, P M|Cristofaro, G|Bufo, P|Tauro, A V
PMID: 3068137
Journal: Scand J Gastroenterol. 1988 Sep;23(7):840-6.
Title: Demonstration of altered cellular DNA content distribution in long-term colon epithelial cell lines with colon cancer genotypes.
Author: Danes, B S|Deangelis, P|Traganos, F|Melamed, M R|Alm, T
PMID: 3227300
Journal: Dis Colon Rectum. 1988 May;31(5):372-7.
Title: Differential diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome I and Lynch syndrome II).
Author: Lynch, H T|Watson, P|Kriegler, M|Lynch, J F|Lanspa, S J|Marcus, J|Smyrk, T|Fitzgibbons, R J Jr|Cristofaro, G
PMID: 3366037
Journal: Biochem Biophys Res Commun. 1988 Aug 30;155(1):463-9.
Title: Chromosome 18 allele loss at the D18S6 locus in human colorectal carcinomas.
Author: Bowman, B M|Wildrick, D M|Alfaro, S R
PMID: 3415702
Journal: Nebr Med J. 1989 Jan;74(1):2-7.
Title: Hereditary nonpolyposis colon cancer: (Lynch syndrome I and II). A challenge for the clinician.
Author: Lynch, H T|Boman, B|Fitzgibbons, R J Jr|Lanspa, S J|Smyrk, T C
PMID: 2538763
Journal: Schweiz Med Wochenschr. 1990 Oct 6;120(40):1451-60.
Title: [Prevention of familial tumor diseases using genetic counseling and early diagnosis].
Author: Muller, H|Vasen, H F
PMID: 1977199
Journal: Cancer Genet Cytogenet. 1991 Jun;53(2):143-60.
Title: Hereditary nonpolyposis colorectal cancer (Lynch syndromes I & II). Genetics, pathology, natural history, and cancer control, Part I.
Author: Lynch, H T|Lanspa, S|Smyrk, T|Boman, B|Watson, P|Lynch, J
PMID: 1648437
Journal: Ann Acad Med Singapore. 1992 Mar;21(2):290-3.
Title: The Singapore Polyposis Registry.
Author: Goh, H S|Wong, J
PMID: 1325751
Journal: Nature. 1993 Sep 16;365(6443):274-6.
Title: Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair.
Author: Strand, M|Prolla, T A|Liskay, R M|Petes, T D
PMID: 8371783
Journal: Cancer. 1993 Jun 1;71(11):3493-501.
Title: Identification of hereditary nonpolyposis colorectal cancer in the general population. The 6-year experience of a population-based registry.
Author: Ponz de Leon, M|Sassatelli, R|Benatti, P|Roncucci, L
PMID: 8387880
Journal: Dis Colon Rectum. 1993 Jan;36(1):1-4.
Title: Surveillance in hereditary nonpolyposis colorectal cancer: an international cooperative study of 165 families. The International Collaborative Group on HNPCC.
Author: Vasen, H F|Mecklin, J P|Watson, P|Utsunomiya, J|Bertario, L|Lynch, P|Svendsen, L B|Cristofaro, G|Muller, H|Khan, P M
PMID: 8416772
Journal: Eur J Epidemiol. 1993 Jan;9(1):26-32.
Title: Familial risk of colo-rectal cancer in a low incidence area in southern Italy.
Author: Centonze, S|Boeing, H|Leoci, C|Bonfiglio, C|Guerra, V|Misciagna, G
PMID: 8472798
Journal:
Title: Lynch Syndrome
Author: Kohlmann, Wendy|Gruber, Stephen B
PMID: 20301390
Journal: Mutat Res. 1994 Sep;325(1):21-9.
Title: Mutagenesis of yeast MW104-1B strain has identified the uncharacterized PMS6 DNA mismatch repair gene locus and additional alleles of existing PMS1, PMS2 and MSH2 genes.
Author: Jeyaprakash, A|Welch, J W|Fogel, S
PMID: 7521009
Journal: Ryoikibetsu Shokogun Shirizu. 1994;(6):89-92.
Title: [Hereditary non-polyposis colorectal cancer: HNPCC].
Author: Yoshikawa, R|Yamamura, T|Utsunomiya, J
PMID: 7736246
Journal: Nihon Rinsho. 1994 Dec;Suppl 6:89-92.
Title: [Hereditary non-polyposis colorectal cancer; HNPCC].
Author: Yoshikawa, R|Yamamura, T|Utsunomiya, J
PMID: 7837674
Journal: Nucleic Acids Res. 1994 Dec 25;22(25):5723-8.
Title: Cloning and expression of the Xenopus and mouse Msh2 DNA mismatch repair genes.
Author: Varlet, I|Pallard, C|Radman, M|Moreau, J|de Wind, N
PMID: 7838728
Journal: Rev Prat. 1994 Dec 15;44(20):2694-9.
Title: [Genes, heredity and colorectal cancer].
Author: Velu, T|Ravelingien, N|Parma, J|Pector, J C
PMID: 7878358
Journal: Science. 1994 Nov 4;266(5186):814-6.
Title: DNA loop repair by human cell extracts.
Author: Umar, A|Boyer, J C|Kunkel, T A
PMID: 7973637
Journal: Anticancer Res. 1994 Jul-Aug;14(4B):1613-5.
Title: What is hereditary nonpolyposis colorectal cancer (HNPCC).
Author: Vasen, H F
PMID: 7979195
Journal: Anticancer Res. 1994 Jul-Aug;14(4B):1617-24.
Title: 25 years of HNPCC.
Author: Lynch, H T|Lynch, J F
PMID: 7979196
Journal: Anticancer Res. 1994 Jul-Aug;14(4B):1625-9.
Title: Epidemiology of HNPCC.
Author: Mecklin, J P|Ponz de Leon, M
PMID: 7979197
Journal: Anticancer Res. 1994 Jul-Aug;14(4B):1657-60.
Title: Genes involved in hereditary nonpolyposis colorectal carcinoma.
Author: Aaltonen, L A|Peltomaki, P
PMID: 7979203
Journal: Anticancer Res. 1994 Jul-Aug;14(4B):1661-4.
Title: The International Collaborative Group on HNPCC.
Author: Vasen, H F|Mecklin, J P|Khan, P M|Lynch, H T
PMID: 7979204
Journal: Br Med Bull. 1994 Jul;50(3):527-35.
Title: The inherited component of cancer.
Author: Easton, D F
PMID: 7987639
Journal: Cancer Res. 1994 Aug 15;54(16):4308-12.
Title: Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation.
Author: Koi, M|Umar, A|Chauhan, D P|Cherian, S P|Carethers, J M|Kunkel, T A|Boland, C R
PMID: 8044777
Journal: Gynecol Oncol. 1994 Aug;54(2):171-4.
Title: Endometrial cancer in four sisters: report of a kindred with presumed cancer family syndrome.
Author: Menko, F H|Verheijen, R H|Everhardt, E|Louwe, L A|Wijnen, J T|Band, S C|Felt-Bersma, R J|Vasen, H F|Khan, P M
PMID: 8063241
Journal: Science. 1994 Mar 18;263(5153):1625-9.
Title: Mutation of a mutL homolog in hereditary colon cancer.
Author: Papadopoulos, N|Nicolaides, N C|Wei, Y F|Ruben, S M|Carter, K C|Rosen, C A|Haseltine, W A|Fleischmann, R D|Fraser, C M|Adams, M D
PMID: 8128251
Journal: Nature. 1994 Mar 17;368(6468):258-61.
Title: Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.
Author: Bronner, C E|Baker, S M|Morrison, P T|Warren, G|Smith, L G|Lescoe, M K|Kane, M|Earabino, C|Lipford, J|Lindblom, A
PMID: 8145827
Journal: Acta Gastroenterol Belg. 1995 May-Aug;58(3-4):270-3.
Title: Contribution of molecular oncology in the detection of colorectal carcinomas.
Author: Ravelingien, N|Pector, J C|Velu, T
PMID: 7491839
Journal: Eur J Cancer Prev. 1995 Aug;4(4):267-9.
Title: Hereditary non-polyposis colorectal cancer (HNPCC or Lynch syndrome)
Author: Ponz de Leon, M
PMID: 7549818
Journal: Nat Genet. 1995 Sep;11(1):99-102.
Title: Monoallelic mutation analysis (MAMA) for identifying germline mutations.
Author: Papadopoulos, N|Leach, F S|Kinzler, K W|Vogelstein, B
PMID: 7550326
Journal: Gastroenterology. 1995 Oct;109(4):1368-74.
Title: In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer.
Author: Luce, M C|Marra, G|Chauhan, D P|Laghi, L|Carethers, J M|Cherian, S P|Hawn, M|Binnie, C G|Kam-Morgan, L N|Cayouette, M C
PMID: 7557107
Journal: Int J Cancer. 1995 Sep 15;62(6):685-90.
Title: Familial aggregation of tumors and detection of hereditary non-polyposis colorectal cancer in 3-year experience of 2 population-based colorectal-cancer registries.
Author: Modica, S|Roncucci, L|Benatti, P|Gafa, L|Tamassia, M G|Dardanoni, L|Ponz de Leon, M
PMID: 7558415
Journal: Tumori. 1995 May-Jun;81(3 Suppl):19-29.
Title: Clinical implications of advances in the molecular genetics of colorectal cancer.
Author: Lynch, H T|Lynch, J F
PMID: 7571049
Journal: Eur J Cancer. 1995 Jul-Aug;31A(7-8):1039-46.
Title: Update on the differential diagnosis, surveillance and management of hereditary non-polyposis colorectal cancer.
Author: Lynch, H T|Smyrk, T|Lynch, J|Fitzgibbons, R Jr|Lanspa, S|McGinn, T
PMID: 7576988
Journal: Nat Med. 1995 Nov;1(11):1203-6.
Title: Founding mutations and Alu-mediated recombination in hereditary colon cancer.
Author: Nystrom-Lahti, M|Kristo, P|Nicolaides, N C|Chang, S Y|Aaltonen, L A|Moisio, A L|Jarvinen, H J|Mecklin, J P|Kinzler, K W|Vogelstein, B
PMID: 7584997
Journal: Cancer Res. 1995 Dec 1;55(23):5556-60.
Title: Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas.
Author: Katabuchi, H|van Rees, B|Lambers, A R|Ronnett, B M|Blazes, M S|Leach, F S|Cho, K R|Hedrick, L
PMID: 7585634
Journal: Cancer Res. 1995 Dec 1;55(23):5664-9.
Title: Microsatellite instability in gynecological sarcomas and in hMSH2 mutant uterine sarcoma cell lines defective in mismatch repair activity.
Author: Risinger, J I|Umar, A|Boyer, J C|Evans, A C|Berchuck, A|Kunkel, T A|Barrett, J C
PMID: 7585651
Journal: J Med Genet. 1995 May;32(5):352-7.
Title: Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome.
Author: Froggatt, N J|Koch, J|Davies, R|Evans, D G|Clamp, A|Quarrell, O W|Weissenbach, J|Hodgson, S V|Ponder, B A|Barton, D E
PMID: 7616541
Journal: Cancer Res. 1995 Sep 1;55(17):3721-5.
Title: Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint.
Author: Hawn, M T|Umar, A|Carethers, J M|Marra, G|Kunkel, T A|Boland, C R|Koi, M
PMID: 7641183
Journal: Minerva Chir. 1995 Mar;50(3):167-75.
Title: [Heredity and colorectal cancer].
Author: Civitelli, S|Civitelli, B|Pacchiarotti, M C|Tanzini, G
PMID: 7659249
Journal: N Engl J Med. 1995 Mar 30;332(13):839-47.
Title: The molecular basis of Turcot's syndrome.
Author: Hamilton, S R|Liu, B|Parsons, R E|Papadopoulos, N|Jen, J|Powell, S M|Krush, A J|Berk, T|Cohen, Z|Tetu, B
PMID: 7661930
Journal: J Natl Cancer Inst. 1995 Aug 2;87(15):1114-25.
Title: Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.
Author: Marra, G|Boland, C R
PMID: 7674315
Journal: Hum Mol Genet. 1995 Feb;4(2):237-42.
Title: Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)
Author: Han, H J|Maruyama, M|Baba, S|Park, J G|Nakamura, Y
PMID: 7757073
Journal: Cancer Res. 1995 Jun 1;55(11):2304-9.
Title: DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines.
Author: Branch, P|Hampson, R|Karran, P
PMID: 7757980
Journal: Gut. 1995 Jan;36(1):90-2.
Title: A screening clinic for relatives of patients with colorectal cancer in a district general hospital.
Author: Carpenter, S|Broughton, M|Marks, C G
PMID: 7890243
Journal: Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1950-4.
Title: Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
Author: Li, G M|Modrich, P
PMID: 7892206
Journal: Cancer Res. 1995 Dec 15;55(24):6063-70.
Title: Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines.
Author: Boyer, J C|Umar, A|Risinger, J I|Lipford, J R|Kane, M|Yin, S|Barrett, J C|Kolodner, R D|Kunkel, T A
PMID: 8521394
Journal: Cancer Res. 1995 Dec 15;55(24):6092-6.
Title: Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families.
Author: Tannergard, P|Lipford, J R|Kolodner, R|Frodin, J E|Nordenskjold, M|Lindblom, A
PMID: 8521398
Journal: Hum Mol Genet. 1995 Nov;4(11):2057-64.
Title: Molecular analysis of mutations in mutator colorectal carcinoma cell lines.
Author: Bhattacharyya, N P|Ganesh, A|Phear, G|Richards, B|Skandalis, A|Meuth, M
PMID: 8589681
Journal: Southeast Asian J Trop Med Public Health. 1995;26 Suppl 1:190-6.
Title: Multistep carcinogenesis in colorectal cancers.
Author: Takami, K|Yana, I|Kurahashi, H|Nishisho, I
PMID: 8629105
Journal: Annu Rev Genet. 1995;29:329-48.
Title: Genetics of hereditary colon cancer.
Author: de la Chapelle, A|Peltomaki, P
PMID: 8825478
Journal: Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1082-6.
Title: Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer.
Author: Moen, C J|Groot, P C|Hart, A A|Snoek, M|Demant, P
PMID: 8577718
Journal: Int J Cancer. 1996 Feb 20;69(1):38-43.
Title: Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome).
Author: Lynch, H T|Smyrk, T|Lynch, J F
PMID: 8600057
Journal: Gastroenterology. 1996 Mar;110(3):682-7.
Title: Better survival rates in patients with MLH1-associated hereditary colorectal cancer.
Author: Sankila, R|Aaltonen, L A|Jarvinen, H J|Mecklin, J P
PMID: 8608876
Journal: Gastroenterology. 1996 Apr;110(4):1020-7.
Title: Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.
Author: Vasen, H F|Wijnen, J T|Menko, F H|Kleibeuker, J H|Taal, B G|Griffioen, G|Nagengast, F M|Meijers-Heijboer, E H|Bertario, L|Varesco, L|Bisgaard, M L|Mohr, J|Fodde, R|Khan, P M
PMID: 8612988
Journal: Mol Cell Biol. 1996 Mar;16(3):884-91.
Title: Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas.
Author: D'Abaco, G M|Whitehead, R H|Burgess, A W
PMID: 8622690
Journal: Cancer Res. 1996 Mar 15;56(6):1382-8.
Title: Genetic heterogeneity and unmapped genes for colorectal cancer.
Author: Lewis, C M|Neuhausen, S L|Daley, D|Black, F J|Swensen, J|Burt, R W|Cannon-Albright, L A|Skolnick, M H
PMID: 8640829
Journal: Tumori. 1996 Mar-Apr;82(2):102-6.
Title: Descriptive epidemiology of hereditary non-polyposis colorectal cancer.
Author: Ponz de Leon, M
PMID: 8644370
Journal: Tumori. 1996 Mar-Apr;82(2):107-13.
Title: Genetic epidemiology of colorectal cancer.
Author: Presciuttini, S|Strigini, P
PMID: 8644371
Journal: Mutat Res. 1996 May;316(5-6):249-59.
Title: Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype.
Author: Malkhosyan, S|McCarty, A|Sawai, H|Perucho, M
PMID: 8649458
Journal: Cancer Res. 1996 Jul 1;56(13):3087-90.
Title: Loss of DNA mismatch repair in acquired resistance to cisplatin.
Author: Aebi, S|Kurdi-Haidar, B|Gordon, R|Cenni, B|Zheng, H|Fink, D|Christen, R D|Boland, C R|Koi, M|Fishel, R|Howell, S B
PMID: 8674066
Journal: Gan To Kagaku Ryoho. 1996 Mar;23(4):395-400.
Title: [Familial cancer and oncogenic factors].
Author: Ohmori, M|Tomita, S|Matuzoe, D|Sasazuki, T
PMID: 8678487
Journal: Gastroenterology. 1996 Aug;111(2):307-17.
Title: Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.
Author: Konishi, M|Kikuchi-Yanoshita, R|Tanaka, K|Muraoka, M|Onda, A|Okumura, Y|Kishi, N|Iwama, T|Mori, T|Koike, M|Ushio, K|Chiba, M|Nomizu, S|Konishi, F|Utsunomiya, J|Miyaki, M
PMID: 8690195
Journal: J Clin Invest. 1996 Jul 1;98(1):199-206.
Title: Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.
Author: Carethers, J M|Hawn, M T|Chauhan, D P|Luce, M C|Marra, G|Koi, M|Boland, C R
PMID: 8690794
Journal: Hum Mutat. 1996;7(4):327-33.
Title: Mutation of the hMSH2 gene in two families with hereditary nonpolyposis colorectal cancer.
Author: Jeon, H M|Lynch, P M|Howard, L|Ajani, J|Levin, B|Frazier, M L
PMID: 8723682
Journal: Jpn J Cancer Res. 1996 Jun;87(6):595-601.
Title: Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.
Author: Akiyama, Y|Nakasaki, H|Nihei, Z|Iwama, T|Nomizu, T|Utsunomiya, J|Yuasa, Y
PMID: 8766523
Journal: Hum Mol Genet. 1996 Jun;5(6):763-9.
Title: DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer.
Author: Nystrom-Lahti, M|Wu, Y|Moisio, A L|Hofstra, R M|Osinga, J|Mecklin, J P|Jarvinen, H J|Leisti, J|Buys, C H|de la Chapelle, A|Peltomaki, P
PMID: 8776590
Journal: Carcinogenesis. 1996 Sep;17(9):1799-804.
Title: Microsatellite instability differences between familial and sporadic ovarian cancers.
Author: Arzimanoglou, I I|Lallas, T|Osborne, M|Barber, H|Gilbert, F
PMID: 8824498
Journal: Ital J Gastroenterol. 1996 May;28(4):232-45.
Title: Genetic basis of tumour development.
Author: Ponz de Leon, M
PMID: 8842841
Journal: J Med Genet. 1996 Aug;33(8):636-40.
Title: Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation.
Author: Hutter, P|Couturier, A|Scott, R J|Alday, P|Delozier-Blanchet, C|Cachat, F|Antonarakis, S E|Joris, F|Gaudin, M|D'Amato, L|Buerstedde, J M
PMID: 8863153
Journal: Scand J Gastroenterol Suppl. 1996;218:92-7.
Title: Recent developments in hereditary nonpolyposis colorectal cancer.
Author: Craanen, M E|Blok, P|Offerhaus, G J|Tytgat, G N
PMID: 8865457
Journal: Hum Mol Genet. 1996 Sep;5(9):1245-52.
Title: Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer.
Author: Moslein, G|Tester, D J|Lindor, N M|Honchel, R|Cunningham, J M|French, A J|Halling, K C|Schwab, M|Goretzki, P|Thibodeau, S N
PMID: 8872463
Journal: Hum Mol Genet. 1996;5 Spec No:1489-94.
Title: Mismatch repair defects in human carcinogenesis.
Author: Eshleman, J R|Markowitz, S D
PMID: 8875255
Journal: J Med Genet. 1996 Sep;33(9):726-30.
Title: Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome.
Author: Froggatt, N J|Brassett, C|Koch, D J|Evans, D G|Hodgson, S V|Ponder, B A|Maher, E R
PMID: 8880570
Journal: Cancer Res. 1996 Nov 1;56(21):4836-40.
Title: Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes.
Author: Thibodeau, S N|French, A J|Roche, P C|Cunningham, J M|Tester, D J|Lindor, N M|Moslein, G|Baker, S M|Liskay, R M|Burgart, L J|Honchel, R|Halling, K C
PMID: 8895729
Journal: Cancer Res. 1996 Nov 1;56(21):4881-6.
Title: The role of DNA mismatch repair in platinum drug resistance.
Author: Fink, D|Nebel, S|Aebi, S|Zheng, H|Cenni, B|Nehme, A|Christen, R D|Howell, S B
PMID: 8895738
Journal: Adv Intern Med. 1996;41:531-52.
Title: The genetic basis of colorectal cancer risk.
Author: Ahnen, D J
PMID: 8903598
Journal: Nihon Rinsho. 1996 Apr;54(4):1014-8.
Title: [Mutations of hMSH2 gene and hMLH1 gene in human colovectal carcinomas].
Author: Yokozaki, H|Yamamoto, S|Tahara, E
PMID: 8920666
Journal: Nihon Rinsho. 1996 Apr;54(4):1072-7.
Title: [Genetic steps in colorectal cancer].
Author: Ichii, S|Utsunomiya, J
PMID: 8920676
Journal: Br J Cancer. 1996 Nov;74(10):1514-7.
Title: Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.
Author: Tomlinson, I P|Ilyas, M|Bodmer, W F
PMID: 8932328
Journal: Curr Biol. 1996 Nov 1;6(11):1528-31.
Title: Processing of O6-methylguanine by mismatch correction in human cell extracts.
Author: Ceccotti, S|Aquilina, G|Macpherson, P|Yamada, M|Karran, P|Bignami, M
PMID: 8939600
Journal: Am J Hum Genet. 1996 Dec;59(6):1243-51.
Title: Age and origin of two common MLH1 mutations predisposing to hereditary colon cancer.
Author: Moisio, A L|Sistonen, P|Weissenbach, J|de la Chapelle, A|Peltomaki, P
PMID: 8940269
Journal: Cancer. 1996 Dec 15;78(12):2478-84.
Title: Mutations of the transforming growth factor-beta type II receptor gene are strongly related to sporadic proximal colon carcinomas with microsatellite instability.
Author: Akiyama, Y|Iwanaga, R|Ishikawa, T|Sakamoto, K|Nishi, N|Nihei, Z|Iwama, T|Saitoh, K|Yuasa, Y
PMID: 8952554
Journal: Gastroenterol Clin North Am. 1996 Dec;25(4):793-803.
Title: Familial risk and colorectal cancer.
Author: Burt, R W
PMID: 8960893
Journal: Cancer Res. 1996 Dec 1;56(23):5375-9.
Title: Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Author: Liu, L|Markowitz, S|Gerson, S L
PMID: 8968088
Journal: Cancer Res. 1996 Dec 15;56(24):5728-33.
Title: Identification of novel germline hMLH1 mutations including a 22 kb Alu-mediated deletion in patients with familial colorectal cancer.
Author: Mauillon, J L|Michel, P|Limacher, J M|Latouche, J B|Dechelotte, P|Charbonnier, F|Martin, C|Moreau, V|Metayer, J|Paillot, B|Frebourg, T
PMID: 8971183
Journal: Cancer Surv. 1996;28:33-46.
Title: Patterns of mutation in cancer cells.
Author: Meuth, M
PMID: 8977027
Journal: Cancer Surv. 1996;28:47-68.
Title: Mismatch repair and cancer.
Author: Jiricny, J
PMID: 8977028
Journal: Virchows Arch. 1996 Dec;429(6):345-52.
Title: Detection of Tn, sialosyl-Tn and T antigens in hereditary nonpolyposis colorectal cancer.
Author: Giuffre, G|Vitarelli, E|Tuccari, G|Ponz de Leon, M|Barresi, G
PMID: 8982378
Journal: J Med Genet. 1996 Dec;33(12):981-5.
Title: Microsatellite instability in early onset and familial colorectal cancer.
Author: Brassett, C|Joyce, J A|Froggatt, N J|Williams, G|Furniss, D|Walsh, S|Miller, R|Evans, D G|Maher, E R
PMID: 9004127
Journal: Z Gastroenterol. 1996 Dec;34(12):813-22.
Title: [Microsatellite instability--a new aspects in genetics and molecular biology of hereditary nonpolyposis and sporadic colorectal tumors].
Author: Kullmann, F|Bocker, T|Scholmerich, J|Ruschoff, J
PMID: 9082661
Journal: Semin Cancer Biol. 1996 Oct;7(5):241-7.
Title: DNA mismatch repair deficient mice in cancer research.
Author: Prolla, T A|Abuin, A|Bradley, A
PMID: 9110401
Journal: Int J Oncol. 1996 Oct;9(4):701-3.
Title: Novel allele of the hMLH1 gene bearing a TTC deletion in the 3' untranslated region.
Author: Palmirotta, R|Veri, M|Curia, M C|Casale, V|Fracasso, P|Stigliano, V|Guadagni, F|Marianicostantini, R|Battista, P|Cama, A
PMID: 21541571
Journal: Genes Chromosomes Cancer. 1997 Jan;18(1):8-18.
Title: Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer.
Author: Viel, A|Genuardi, M|Capozzi, E|Leonardi, F|Bellacosa, A|Paravatou-Petsotas, M|Pomponi, M G|Fornasarig, M|Percesepe, A|Roncucci, L|Tamassia, M G|Benatti, P|Ponz de Leon, M|Valenti, A|Covino, M|Anti, M|Foletto, M|Boiocchi, M|Neri, G
PMID: 8993976
Journal: Genes Chromosomes Cancer. 1997 Jan;18(1):42-9.
Title: Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability.
Author: Herfarth, K K|Kodner, I J|Whelan, A J|Ivanovich, J L|Bracamontes, J R|Wells, S A Jr|Goodfellow, P J
PMID: 8993979
Journal: Gastroenterology. 1997 Feb;112(2):327-34.
Title: Clinical and molecular features of the hereditary mixed polyposis syndrome.
Author: Whitelaw, S C|Murday, V A|Tomlinson, I P|Thomas, H J|Cottrell, S|Ginsberg, A|Bukofzer, S|Hodgson, S V|Skudowitz, R B|Jass, J R|Talbot, I C|Northover, J M|Bodmer, W F|Solomon, E
PMID: 9024286
Journal: J Med Genet. 1997 Jan;34(1):39-42.
Title: Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer.
Author: Tomlinson, I P|Beck, N E|Homfray, T|Harocopos, C J|Bodmer, W F
PMID: 9032648
Journal: Cancer Res. 1997 Mar 1;57(5):808-11.
Title: Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.
Author: Kane, M F|Loda, M|Gaida, G M|Lipman, J|Mishra, R|Goldman, H|Jessup, J M|Kolodner, R
PMID: 9041175
Journal: Am J Surg. 1997 Jan;173(1):37-41; discussion 42-3.
Title: Advances in molecular genetics.
Author: Lairmore, T C|Norton, J A
PMID: 9046882
Journal: Hum Genet. 1997 Feb;99(2):219-24.
Title: Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria.
Author: Beck, N E|Tomlinson, I P|Homfray, T|Frayling, I|Hodgson, S V|Harocopos, C|Bodmer, W F
PMID: 9048925
Journal: Br J Surg. 1997 Feb;84(2):233-7.
Title: Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled.
Author: Beck, N E|Tomlinson, I P|Homfray, T|Hodgson, S V|Harocopos, C J|Bodmer, W F
PMID: 9052445
Journal: Int J Cancer. 1997 Mar 4;70(5):499-501.
Title: Microsatellite instability in cervical and endometrial carcinomas.
Author: Helland, A|Borresen-Dale, A L|Peltomaki, P|Hektoen, M|Kristensen, G B|Nesland, J M|de la Chapelle, A|Lothe, R A
PMID: 9052745
Journal: Mol Med Today. 1997 Feb;3(2):61-8.
Title: Microsatellite instability in human solid tumors.
Author: Lothe, R A
PMID: 9060003
Journal: Cancer Genet Cytogenet. 1997 Jan;93(1):84-99.
Title: An update of HNPCC (Lynch syndrome).
Author: Lynch, H T|Smyrk, T|Lynch, J
PMID: 9062584
Journal: Hum Mutat. 1997;9(2):164-71.
Title: Mutational analysis of the hMLH1 gene using an automated two-dimensional DNA typing system.
Author: Sasaki, S|Tokino, T|Miyatsu, T|Muto, T|Nakamura, Y
PMID: 9067757
Journal: Genes Chromosomes Cancer. 1997 Apr;18(4):269-78.
Title: MSH2 and MLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis.
Author: Wu, Y|Nystrom-Lahti, M|Osinga, J|Looman, M W|Peltomaki, P|Aaltonen, L A|de la Chapelle, A|Hofstra, R M|Buys, C H
PMID: 9087566
Journal: Mutat Res. 1997 Mar 12;383(2):177-82.
Title: DNA mismatch repair in lymphoblastoid cells from hereditary non-polyposis colorectal cancer (HNPCC) patients is normal under conditions of rapid cell division and increased mutational load.
Author: Tomlinson, I P|Hampson, R|Karran, P|Bodmer, W F
PMID: 9088350
Journal: Nihon Geka Gakkai Zasshi. 1997 Mar;98(3):366-72.
Title: [Molecular-pathological problems of genetic diagnosis for colorectal cancer].
Author: Tomita, N|Monden, T|Sekimoto, M|Monden, M
PMID: 9101543
Journal: Cancer Lett. 1997 Mar 19;114(1-2):309-11.
Title: Meat consumption and preparation, and genetic susceptibility in relation to colorectal adenomas.
Author: Voskuil, D W|Kampman, E|Grubben, M J|Goldbohm, R A|Brants, H A|Vasen, H F|Nagengast, F M|Van't Veer, P
PMID: 9103318
Journal: Adv Cancer Res. 1997;71:93-119.
Title: Mutations predisposing to hereditary nonpolyposis colorectal cancer.
Author: Peltomaki, P|de la Chapelle, A
PMID: 9111864
Journal: Eur J Hum Genet. 1997 Mar-Apr;5(2):89-93.
Title: The fragile X CGG repeat shows a marked level of instability in hereditary non-polyposis colorectal cancer patients.
Author: Fulchignoni-Lataud, M C|Olchwang, S|Serre, J L
PMID: 9195158
Journal: Carcinogenesis. 1997 Jun;18(6):1127-33.
Title: Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair.
Author: Ohzeki, S|Tachibana, A|Tatsumi, K|Kato, T
PMID: 9214593
Journal: Int J Cancer. 1997 Jun 20;74(3):281-5.
Title: Disease expression in Swiss hereditary non-polyposis colorectal cancer (HNPCC) kindreds.
Author: Heinimann, K|Muller, H|Weber, W|Scott, R J
PMID: 9221805
Journal: Z Arztl Fortbild Qualitatssich. 1997 Mar;91(2):125-33.
Title: [Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy].
Author: Jacobasch, G|Jacobasch, K H
PMID: 9244653
Journal: Hum Genet. 1997 Sep;100(3-4):362-4.
Title: Hereditary nonpolyposis colorectal cancer: causative role of a germline missense mutation in the hMLH1 gene confirmed by the independent occurrence of the same somatic mutation in tumour tissue.
Author: Wang, Y|Friedl, W|Lamberti, C|Ruelfs, C|Kruse, R|Propping, P
PMID: 9272156
Journal: Cancer Res. 1997 Sep 1;57(17):3798-803.
Title: Genomic DNA-based hMSH2 and hMLH1 mutation screening in 32 Eastern United States hereditary nonpolyposis colorectal cancer pedigrees.
Author: Weber, T K|Conlon, W|Petrelli, N J|Rodriguez-Bigas, M|Keitz, B|Pazik, J|Farrell, C|O'Malley, L|Oshalim, M|Abdo, M|Anderson, G|Stoler, D|Yandell, D
PMID: 9288790
Journal: Cancer Res. 1997 Sep 15;57(18):3920-3.
Title: Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.
Author: Akiyama, Y|Sato, H|Yamada, T|Nagasaki, H|Tsuchiya, A|Abe, R|Yuasa, Y
PMID: 9307272
Journal: Am J Hum Genet. 1997 Aug;61(2):329-35.
Title: Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
Author: Wijnen, J|Khan, P M|Vasen, H|van der Klift, H|Mulder, A|van Leeuwen-Cornelisse, I|Bakker, B|Losekoot, M|Moller, P|Fodde, R
PMID: 9311737
Journal: Pathologica. 1997 Feb;89(1):84-5.
Title: [Hereditary colorectal cancer (HNPCC or Lynch syndrome)].
Author: Ponz de Leon, M
PMID: 9312738
Journal: J Natl Cancer Inst. 1997 Oct 15;89(20):1537-41.
Title: Loss of DNA mismatch repair: effects on the rate of mutation to drug resistance.
Author: de las Alas, M M|Aebi, S|Fink, D|Howell, S B|Los, G
PMID: 9337351
Journal: Br J Dermatol. 1997 Sep;137(3):356-60.
Title: Widespread microsatellite instability in sebaceous tumours of patients with the Muir-Torre syndrome.
Author: Peris, K|Onorati, M T|Keller, G|Magrini, F|Donati, P|Muscardin, L|Hofler, H|Chimenti, S
PMID: 9349329
Journal: Cancer Res. 1997 Nov 1;57(21):4749-56.
Title: Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.
Author: Dietmaier, W|Wallinger, S|Bocker, T|Kullmann, F|Fishel, R|Ruschoff, J
PMID: 9354436
Journal: Cancer Res. 1997 Nov 15;57(22):5143-7.
Title: Role of DNA mismatch repair in the cytotoxicity of ionizing radiation.
Author: Fritzell, J A|Narayanan, L|Baker, S M|Bronner, C E|Andrew, S E|Prolla, T A|Bradley, A|Jirik, F R|Liskay, R M|Glazer, P M
PMID: 9371516
Journal: Dis Colon Rectum. 1997 Oct;40(10 Suppl):S23-8.
Title: Undectable expression of hMLH1 protein in sporadic colorectal cancer with replication error phenotype.
Author: Koike, J|Yamada, K|Takano, S|Kikuchi, Y|Hemmi, H|Koi, M|Tsujita, K|Yanagita, K|Yoshio, T|Shimatake, H
PMID: 9378008
Journal: Hum Genet. 1997 Nov;101(1):51-5.
Title: Tumorigenesis in colorectal tumors from patients with hereditary non-polyposis colorectal cancer.
Author: Tannergard, P|Liu, T|Weger, A|Nordenskjold, M|Lindblom, A
PMID: 9385369
Journal: Int J Cancer. 1997 Dec 10;73(6):831-6.
Title: Germline hMSH2 and hMLH1 gene mutations in incomplete HNPCC families.
Author: Wang, Q|Desseigne, F|Lasset, C|Saurin, J C|Navarro, C|Yagci, T|Keser, I|Bagci, H|Luleci, G|Gelen, T|Chayvialle, J A|Puisieux, A|Ozturk, M
PMID: 9399661
Journal: Cancer Epidemiol Biomarkers Prev. 1997 Dec;6(12):987-91.
Title: Etiology, natural history, management and molecular genetics of hereditary nonpolyposis colorectal cancer (Lynch syndromes): genetic counseling implications.
Author: Lynch, H T|Lemon, S J|Karr, B|Franklin, B|Lynch, J F|Watson, P|Tinley, S|Lerman, C|Carter, C
PMID: 9419392
Journal: Cancer Epidemiol Biomarkers Prev. 1997 Dec;6(12):1057-64.
Title: Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds.
Author: Nakahara, M|Yokozaki, H|Yasui, W|Dohi, K|Tahara, E
PMID: 9419403
Journal: Oncogene. 1997 Dec 4;15(23):2877-81.
Title: Drastic genetic instability of tumors and normal tissues in Turcot syndrome.
Author: Miyaki, M|Nishio, J|Konishi, M|Kikuchi-Yanoshita, R|Tanaka, K|Muraoka, M|Nagato, M|Chong, J M|Koike, M|Terada, T|Kawahara, Y|Fukutome, A|Tomiyama, J|Chuganji, Y|Momoi, M|Utsunomiya, J
PMID: 9419979
Journal: Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300.
Title: Molecular biology of colorectal cancer.
Author: Gryfe, R|Swallow, C|Bapat, B|Redston, M|Gallinger, S|Couture, J
PMID: 9438104
Journal: Pathobiology. 1997;65(6):293-300.
Title: Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction.
Author: Wei, Q|Guan, Y|Cheng, L|Radinsky, R|Bar-Eli, M|Tsan, R|Li, L|Legerski, R J
PMID: 9491849
Journal: Surg Oncol. 1997 Nov;6(3):143-56.
Title: Molecular advances in the etiology and treatment of colorectal cancer.
Author: Bradley, B A|Evers, B M
PMID: 9576630
Journal: Gastroenterol Clin Biol. 1997;21(12):955-9.
Title: [Colorectal adenocarcinoma in patients under 40 years of age].
Author: Pocard, M|Gallot, D|De Rycke, Y|Malafosse, M
PMID: 9587559
Journal: Ann N Y Acad Sci. 1997 Dec 29;833:1-28.
Title: Cancer genetics in the new era of molecular biology.
Author: Lynch, H T|Fusaro, R M|Lynch, J F
PMID: 9616736
Journal: J Chir (Paris). 1997 Dec;134(7-8):279-82.
Title: [The application of molecular technics in the management of colorectal cancer].
Author: Laurent-Puig, P|Cugnenc, P H
PMID: 9772989
Journal: Oncol Rep. 1997 May-Jun;4(3):653-5.
Title: Decreased expression of MLH1, MSH2, PMS1 and PMS2 in pigmented lesions indicates accumulation of failed DNA repair along with malignant transformation and tumour progression.
Author: Korabiowska, M|Dengler, H|Kellner, S|Stachura, J|Schauer, A
PMID: 21590118
Journal: Cancer. 1998 Jan 15;82(2):279-85.
Title: Clinicopathologic and genetic features of nonfamilial colorectal carcinomas with DNA replication errors.
Author: Senba, S|Konishi, F|Okamoto, T|Kashiwagi, H|Kanazawa, K|Miyaki, M|Konishi, M|Tsukamoto, T
PMID: 9445183
Journal: Int J Oncol. 1998 Feb;12(2):377-82.
Title: DNA synthesis, mismatch repair and cancer.
Author: Hoffmann, J S|Cazaux, C
PMID: 9458365
Journal: Int J Oncol. 1998 Mar;12(3):609-15.
Title: Growth suppression mediated by transfection of wild-type hMLH1 in human cancer cells expressing endogenous truncated hMLH1 protein.
Author: Shin, K H|Han, H J|Park, J G
PMID: 9472100
Journal: Cancer Res. 1998 Feb 15;58(4):767-78.
Title: Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation.
Author: Davis, T W|Wilson-Van Patten, C|Meyers, M|Kunugi, K A|Cuthill, S|Reznikoff, C|Garces, C|Boland, C R|Kinsella, T J|Fishel, R|Boothman, D A
PMID: 9485033
Journal: J Natl Cancer Inst. 1998 Feb 18;90(4):316-21.
Title: Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers.
Author: Cheng, A J|Tang, R|Wang, J Y|See, L C|Wang, T C
PMID: 9486818
Journal: Hum Genet. 1998 Jan;102(1):15-20.
Title: Characterization of MLH1 and MSH2 alternative splicing and its relevance to molecular testing of colorectal cancer susceptibility.
Author: Genuardi, M|Viel, A|Bonora, D|Capozzi, E|Bellacosa, A|Leonardi, F|Valle, R|Ventura, A|Pedroni, M|Boiocchi, M|Neri, G
PMID: 9490293
Journal: Oncology. 1998 Mar-Apr;55(2):103-8.
Title: Molecular genetics and clinical-pathology features of hereditary nonpolyposis colorectal carcinoma (Lynch syndrome): historical journey from pedigree anecdote to molecular genetic confirmation.
Author: Lynch, H T|Smyrk, T|Lynch, J F
PMID: 9499183
Journal: Int J Oncol. 1998 Apr;12(4):947-55.
Title: Genetic identification and management of hereditary nonpolyposis colorectal cancer.
Author: Park, J G|Yuan, Y
PMID: 9499460
Journal: Cancer Res. 1998 Mar 1;58(5):997-1003.
Title: Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer.
Author: Yamamoto, H|Sawai, H|Weber, T K|Rodriguez-Bigas, M A|Perucho, M
PMID: 9500462
Journal: Nat Genet. 1998 Mar;18(3):276-9.
Title: Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair.
Author: Prolla, T A|Baker, S M|Harris, A C|Tsao, J L|Yao, X|Bronner, C E|Zheng, B|Gordon, M|Reneker, J|Arnheim, N|Shibata, D|Bradley, A|Liskay, R M
PMID: 9500552
Journal: J Mol Biol. 1998 Mar 6;276(4):705-19.
Title: Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair.
Author: Ciotta, C|Ceccotti, S|Aquilina, G|Humbert, O|Palombo, F|Jiricny, J|Bignami, M
PMID: 9500919
Journal: Int J Cancer. 1998 Mar 16;75(6):835-9.
Title: MLH1 and MSH2 constitutional mutations in colorectal cancer families not meeting the standard criteria for hereditary nonpolyposis colorectal cancer.
Author: Genuardi, M|Anti, M|Capozzi, E|Leonardi, F|Fornasarig, M|Novella, E|Bellacosa, A|Valenti, A|Gasbarrini, G B|Roncucci, L|Benatti, P|Percesepe, A|Ponz de Leon, M|Coco, C|de Paoli, A|Valentini, M|Boiocchi, M|Neri, G|Viel, A
PMID: 9506527
Journal: Hum Hered. 1998 Mar-Apr;48(2):87-91.
Title: A novel missense mutation in the DNA mismatch repair gene hMLH1 present among East Asians but not among Europeans.
Author: Wang, Y|Friedl, W|Lamberti, C|Nothen, M M|Kruse, R|Propping, P
PMID: 9526167
Journal: Pathol Res Pract. 1998;194(1):3-9.
Title: Expression of hMSH2 and hMLH1 in colorectal carcinomas with microsatellite instability.
Author: Kim, H|Piao, Z|Kim, J W|Choi, J S|Kim, N K|Lee, J M|Park, J H
PMID: 9542742
Journal: Oncogene. 1998 Mar 12;16(10):1259-65.
Title: Mismatch repair deficiency leads to a unique mode of colorectal tumorigenesis characterized by intratumoral heterogeneity.
Author: Habano, W|Sugai, T|Nakamura, S
PMID: 9546427
Journal: Dis Colon Rectum. 1998 Apr;41(4):428-33.
Title: Colorectal and extracolonic cancer variations in MLH1/MSH2 hereditary nonpolyposis colorectal cancer kindreds and the general population.
Author: Lin, K M|Shashidharan, M|Ternent, C A|Thorson, A G|Blatchford, G J|Christensen, M A|Lanspa, S J|Lemon, S J|Watson, P|Lynch, H T
PMID: 9559626
Journal: Dis Colon Rectum. 1998 Apr;41(4):434-40.
Title: Germline mutations of hMLH1 and hMSH2 genes in patients with suspected hereditary nonpolyposis colorectal cancer and sporadic early-onset colorectal cancer.
Author: Yuan, Y|Han, H J|Zheng, S|Park, J G
PMID: 9559627
Journal: Cancer Res. 1998 Apr 15;58(8):1713-8.
Title: Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.
Author: Thibodeau, S N|French, A J|Cunningham, J M|Tester, D|Burgart, L J|Roche, P C|McDonnell, S K|Schaid, D J|Vockley, C W|Michels, V V|Farr, G H Jr|O'Connell, M J
PMID: 9563488
Journal: Cancer. 1998 May 15;82(10):1808-20.
Title: Microsatellite instability in human solid tumors.
Author: Arzimanoglou, I I|Gilbert, F|Barber, H R
PMID: 9587112
Journal: Int J Oncol. 1998 Jun;12(6):1315-9.
Title: Reduced expression of mismatch repair genes in colorectal cancer patients in Egypt.
Author: Soliman, A S|Bondy, M L|Guan, Y|El-Badawi, S|Mokhtar, N|Bayomi, S|Raouf, A A|Ismail, S|McPherson, R S|Abdel-Hakim, T F|Beasley, R P|Levin, B|Wei, Q
PMID: 9592192
Journal: N Engl J Med. 1998 May 21;338(21):1481-7.
Title: Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease.
Author: Aaltonen, L A|Salovaara, R|Kristo, P|Canzian, F|Hemminki, A|Peltomaki, P|Chadwick, R B|Kaariainen, H|Eskelinen, M|Jarvinen, H|Mecklin, J P|de la Chapelle, A
PMID: 9593786
Journal: Clin Genet. 1998 Feb;53(2):131-5.
Title: DGGE screening of mutations in mismatch repair genes (hMSH2 and hMLH1) in 34 Swedish families with colorectal cancer.
Author: Liu, T|Wahlberg, S|Rubio, C|Holmberg, E|Gronberg, H|Lindblom, A
PMID: 9611074
Journal: Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6870-5.
Title: Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Author: Herman, J G|Umar, A|Polyak, K|Graff, J R|Ahuja, N|Issa, J P|Markowitz, S|Willson, J K|Hamilton, S R|Kinzler, K W|Kane, M F|Kolodner, R D|Vogelstein, B|Kunkel, T A|Baylin, S B
PMID: 9618505
Journal: J Hum Genet. 1998;43(2):143-5.
Title: Novel germline mutations of hMSH2 in a patient with hereditary nonpolyposis colorectal cancer (HNPCC) and in a patient with six primary cancers.
Author: Okamura, S|Koyama, K|Miyoshi, Y|Monden, M|Takami, M
PMID: 9621522
Journal: Rinsho Byori. 1998 May;46(5):406-12.
Title: [Analysis of genomic instability by fluorescence DNA sequencer].
Author: Maekawa, M|Sugano, K|Kashiwabara, H|Taniguchi, T|Nomura, Y|Fujita, S|Ohkura, H|Kakizoe, T
PMID: 9627490
Journal: Gene. 1998 Jun 15;213(1-2):159-67.
Title: Functional genetic tests of DNA mismatch repair protein activity in Saccharomyces cerevisiae.
Author: Polaczek, P|Putzke, A P|Leong, K|Bitter, G A
PMID: 9630599
Journal: Am J Hum Genet. 1998 Jul;63(1):63-70.
Title: Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria.
Author: Kruse, R|Rutten, A|Lamberti, C|Hosseiny-Malayeri, H R|Wang, Y|Ruelfs, C|Jungck, M|Mathiak, M|Ruzicka, T|Hartschuh, W|Bisceglia, M|Friedl, W|Propping, P
PMID: 9634524
Journal: Int J Cancer. 1998 Jul 3;77(1):29-32.
Title: Risk factors for endometrial cancer according to familial susceptibility.
Author: Fornasarig, M|Campagnutta, E|Talamini, R|Franceschi, S|Boz, G|Scarabelli, C|Andreaus, C M|Scozzari, G|Valentini, M
PMID: 9639390
Journal: Br J Cancer. 1998 Jun;77 Suppl 4:8-11.
Title: Ongoing and unsaid on oxaliplatin: the hope.
Author: Cvitkovic, E
PMID: 9647613
Journal: Cancer Genet Cytogenet. 1998 Jul 1;104(1):48-51.
Title: Search for chromosome instability in lymphocytes with germ-line mutations in DNA mismatch repair genes.
Author: Lindor, N M|Jalal, S M|VanDeWalker, T J|Cunningham, J M|Dahl, R J|Thibodeau, S N
PMID: 9648558
Journal: Cancer. 1998 Jul 15;83(2):240-4.
Title: Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International Collaborative Group on HNPCC.
Author: Rodriguez-Bigas, M A|Vasen, H F|Lynch, H T|Watson, P|Myrhoj, T|Jarvinen, H J|Mecklin, J P|Macrae, F|St John, D J|Bertario, L|Fidalgo, P|Madlensky, L|Rozen, P
PMID: 9669805
Journal: Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8698-702.
Title: Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.
Author: Veigl, M L|Kasturi, L|Olechnowicz, J|Ma, A H|Lutterbaugh, J D|Periyasamy, S|Li, G M|Drummond, J|Modrich, P L|Sedwick, W D|Markowitz, S D
PMID: 9671741
Journal: Cancer Epidemiol Biomarkers Prev. 1998 Jul;7(7):639-41.
Title: Frequency and type of colorectal tumors in asymptomatic high-risk individuals in families with hereditary nonpolyposis colorectal cancer.
Author: Ponz de Leon, M|Della Casa, G|Benatti, P|Percesepe, A|di Gregorio, C|Fante, R|Roncucci, L
PMID: 9681535
Journal: Int J Oncol. 1998 Sep;13(3):565-9.
Title: Lack of PMS2 gene-truncating mutations in patients with hereditary colorectal cancer.
Author: Viel, A|Novella, E|Genuardi, M|Capozzi, E|Fornasarig, M|Pedroni, M|Santarosa, M|De Leon, M P|Della Puppa, L|Anti, M|Boiocchi, M
PMID: 9683794
Journal: Nihon Geka Gakkai Zasshi. 1998 Jun;99(6):336-44.
Title: [Molecular biological background of FAP and HNPCC, and treatment strategies of both diseases depend upon genetic information].
Author: Baba, S
PMID: 9695069
Journal: Nat Genet. 1998 Aug;19(4):384-9.
Title: Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae.
Author: Shimodaira, H|Filosi, N|Shibata, H|Suzuki, T|Radice, P|Kanamaru, R|Friend, S H|Kolodner, R D|Ishioka, C
PMID: 9697702
Journal: Cancer Res. 1998 Aug 1;58(15):3455-60.
Title: Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.
Author: Cunningham, J M|Christensen, E R|Tester, D J|Kim, C Y|Roche, P C|Burgart, L J|Thibodeau, S N
PMID: 9699680
Journal: Digestion. 1998 Aug;59(5):481-92.
Title: Genetics of colonic cancer.
Author: Lynch, H T|Lynch, J F
PMID: 9705533
Journal: N Engl J Med. 1998 Aug 20;339(8):511-8.
Title: Clinical findings with implications for genetic testing in families with clustering of colorectal cancer.
Author: Wijnen, J T|Vasen, H F|Khan, P M|Zwinderman, A H|van der Klift, H|Mulder, A|Tops, C|Moller, P|Fodde, R
PMID: 9709044
Journal: J Pathol. 1998 Jun;185(2):123-9.
Title: DNA mismatch repair and colorectal cancer.
Author: Toft, N J|Arends, M J
PMID: 9713337
Journal: Am J Hum Genet. 1998 Sep;63(3):749-59.
Title: Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
Author: Farrington, S M|Lin-Goerke, J|Ling, J|Wang, Y|Burczak, J D|Robbins, D J|Dunlop, M G
PMID: 9718327
Journal: Cancer. 1998 Sep 1;83(5):889-95.
Title: Microsatellite instability and p53 mutations in sporadic right and left colon carcinoma: different clinical and molecular implications.
Author: Lleonart, M E|Garcia-Foncillas, J|Sanchez-Prieto, R|Martin, P|Moreno, A|Salas, C|Ramon y Cajal, S
PMID: 9731891
Journal: Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11301-6.
Title: Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection.
Author: Ruschoff, J|Wallinger, S|Dietmaier, W|Bocker, T|Brockhoff, G|Hofstadter, F|Fishel, R
PMID: 9736731
Journal: Pathologe. 1998 Jul;19(4):269-78.
Title: [Molecular cancer disposition diagnosis exemplified by colorectal carcinoma. What is the contribution of pathology?].
Author: Ruschoff, J|Dietmaier, W|Bocker, T|Wallinger, S|Kullmann, F|Beham, A|Hofstadter, F
PMID: 9746911
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Oct 10;15(5):263-6.
Title: [Val384Asp in hMLH1 gene in Chinese, Japanese and German and its etiological role in colorectal cancer].
Author: Wang, Y|Friedl, W|Propping, P|Li, J|Li, Z|Wang, J
PMID: 9758868
Journal: Dis Colon Rectum. 1998 Oct;41(10):1250-3; discussion 1253-5.
Title: In a resource-poor country, mutation identification has the potential to reduce the cost of family management for hereditary nonpolyposis colorectal cancer.
Author: Goldberg, P A|Madden, M V|Harocopos, C|Felix, R|Westbrook, C|Ramesar, R S
PMID: 9788388
Journal: Clin Chem Lab Med. 1998 Aug;36(8):641-4.
Title: The impact of molecular diagnosis on familial colorectal cancer.
Author: Bennett, G|Rudzki, Z|Cole, S|Young, G|Suthers, G
PMID: 9806477
Journal: Oncogene. 1998 Nov 5;17(18):2413-7.
Title: MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.
Author: Esteller, M|Levine, R|Baylin, S B|Ellenson, L H|Herman, J G
PMID: 9811473
Journal: Curr Biol. 1998 Nov 19;8(23):1243-52.
Title: TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis.
Author: Oft, M|Heider, K H|Beug, H
PMID: 9822576
Journal: Int J Oncol. 1998 Dec;13(6):1147-51.
Title: Expression of the mismatch repair gene hMSH2 in sporadic colorectal cancer.
Author: Maeda, K|Nishiguchi, Y|Onoda, N|Otani, H|Nakata, B|Yamada, S|Okuno, M|Sowa, M|Chung, K H
PMID: 9824623
Journal: Clin Genet. 1998 Oct;54(4):368-70.
Title: I1307K APC and hMLH1 mutations in a non-Jewish family with hereditary non-polyposis colorectal cancer.
Author: Yuan, Z Q|Kasprzak, L|Gordon, P H|Pinsky, L|Foulkes, W D
PMID: 9831355
Journal: Int J Cancer. 1998 Dec 9;78(6):680-4.
Title: Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer.
Author: Hutter, P|Couturier, A|Membrez, V|Joris, F|Sappino, A P|Chappuis, P O
PMID: 9833759
Journal: Gastroenterology. 1998 Dec;115(6):1387-94.
Title: Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer.
Author: Moisio, A L|Sistonen, P|Mecklin, J P|Jarvinen, H|Peltomaki, P
PMID: 9834266
Journal: Mutat Res. 1998 Dec 3;422(2):279-83.
Title: Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.
Author: Kato, T|Yatagai, F|Glickman, B W|Tachibana, A|Ikenaga, M
PMID: 9838164
Journal: J Gastrointest Surg. 1998 Jan-Feb;2(1):67-71.
Title: Cumulative incidence of colorectal and extracolonic cancers in MLH1 and MSH2 mutation carriers of hereditary nonpolyposis colorectal cancer.
Author: Lin, K M|Shashidharan, M|Thorson, A G|Ternent, C A|Blatchford, G J|Christensen, M A|Watson, P|Lemon, S J|Franklin, B|Karr, B|Lynch, J|Lynch, H T
PMID: 9841970
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Dec 10;15(6):333-6.
Title: [Germline mutation analysis in hMLH 1 and hMSH 2 genes in hereditary nonpolyposis colorectal cancer and colorectal cancer patients with familial history].
Author: Wang, Y|Friedl, W|Propping, P
PMID: 9845760
Journal: Cancer Res. 1998 Dec 1;58(23):5473-7.
Title: Reduced COX-2 protein in colorectal cancer with defective mismatch repair.
Author: Karnes, W E Jr|Shattuck-Brandt, R|Burgart, L J|DuBois, R N|Tester, D J|Cunningham, J M|Kim, C Y|McDonnell, S K|Schaid, D J|Thibodeau, S N
PMID: 9850081
Journal: Carcinogenesis. 1998 Nov;19(11):1925-9.
Title: Allelic losses and DNA methylation at DNA mismatch repair loci in sporadic colorectal cancer.
Author: Benachenhou, N|Guiral, S|Gorska-Flipot, I|Michalski, R|Labuda, D|Sinnett, D
PMID: 9855004
Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1408-10.
Title: [Modification of surgical strategy in HNPCC by molecular and clinical aspects].
Author: Wullenweber, H P|Sutter, C|Kadmon, M|Gebert, J|von Knebel-Doeberitz, M|Herfarth, C
PMID: 9931896
Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1467-9.
Title: [Rectal carcinomas in HNPCC].
Author: Moslein, G|Nelson, H|Thibodeau, S|Dozois, R R
PMID: 9931914
Journal: Oncologist. 1998;3(5):319-338.
Title: Hereditary Factors in Gynecologic Cancer.
Author: Lynch|Casey|Shaw|Lynch
PMID: 10388122
Journal: Rev Hosp Clin Fac Med Sao Paulo. 1998 Sep-Oct;53(5):257-9.
Title: Genetics and colorectal cancer (HNPCC) in adolescence. A case report.
Author: Nahas, S C|Borba, M R|Lourencao, J L|Nahas, C S|Lopes, L H
PMID: 10436636
Journal: Hum Mutat. 1998;12(1):73.
Title: Four new mutations in the DNA mismatch repair gene MLH1 in colorectal cancers with microsatellite instability. Mutations in brief no. 157. Online.
Author: Klaus, K|Herfarth, F|Ogunbiyi, O A|Moley, J F|Kodner, I J|Wells, S A Jr|Goodfellow, P J
PMID: 10627141
Journal: Hum Mutat. 1998;12(3):216-7.
Title: hMLH1 mutations in hereditary nonpolyposis colorectal cancer kindreds. Mutations in brief no. 182. Online.
Author: Panariello, L|Scarano, M I|de Rosa, M|Capasso, L|Renda, A|Riegler, G|Rossi, G B|Salvatore, F|Izzo, P
PMID: 10660333
Journal: Zhonghua Bing Li Xue Za Zhi. 1998 Oct;27(5):359-61.
Title: [The relation between DNA replication error and clinicopathological features of colorectal carcinoma].
Author: Xu, N|Qiu, H|Ding, Y
PMID: 11245012
Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):689-91.
Title: [HNPCC-associated stomach carcinomas display aggressive growth in orthotopic transplantation to the SCID mouse].
Author: Muller, A|Alves, F|Breul, M|Becker, H
PMID: 14518342
Journal: Community Genet. 1998;1(4):229-36.
Title: Hereditary nonpolyposis colorectal cancer: an approach to the selection of candidates to genetic testing based on clinical and molecular characteristics.
Author: Viel, A|Genuardi, M|Lucci-Cordisco, E|Capozzi, E|Rovella, V|Fornasarig, M|Ponz de Leon, M|Anti, M|Pedroni, M|Bellacosa, A|Percesepe, A|Covino, M|Benatti, P|Del Tin, L|Roncucci, L|Valentini, M|Boiocchi, M|Neri, G
PMID: 15178966
Journal: Exp Cell Res. 1999 Jan 10;246(1):1-10.
Title: Microsatellite instability in human cancer: a prognostic marker for chemotherapy?
Author: Claij, N|te Riele, H
PMID: 9882509
Journal: Cancer Res. 1999 Jan 1;59(1):159-64.
Title: hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability.
Author: Leung, S Y|Yuen, S T|Chung, L P|Chu, K M|Chan, A S|Ho, J C
PMID: 9892201
Journal: Nat Genet. 1999 Jan;21(1):123-7.
Title: Mammalian MutS homologue 5 is required for chromosome pairing in meiosis.
Author: Edelmann, W|Cohen, P E|Kneitz, B|Winand, N|Lia, M|Heyer, J|Kolodner, R|Pollard, J W|Kucherlapati, R
PMID: 9916805
Journal: Cancer Res. 1999 Jan 15;59(2):462-6.
Title: Causes and consequences of microsatellite instability in endometrial carcinoma.
Author: Gurin, C C|Federici, M G|Kang, L|Boyd, J
PMID: 9927063
Journal: J Hum Genet. 1999;44(1):18-21.
Title: Germline mutations in a polycytosine repeat of the hMSH6 gene in Korean hereditary nonpolyposis colorectal cancer.
Author: Shin, K H|Ku, J L|Park, J G
PMID: 9929971
Journal: Int J Cancer. 1999 Jan 18;80(2):183-7.
Title: Survival of patients with hereditary colorectal cancer: comparison of HNPCC and colorectal cancer in FAP patients with sporadic colorectal cancer.
Author: Bertario, L|Russo, A|Sala, P|Eboli, M|Radice, P|Presciuttini, S|Andreola, S|Rodriguez-Bigas, M A|Pizzetti, P|Spinelli, P
PMID: 9935197
Journal: Nat Genet. 1999 Feb;21(2):163-7.
Title: Cancer epigenetics comes of age.
Author: Jones, P A|Laird, P W
PMID: 9988266
Journal: J Med Genet. 1999 Feb;36(2):97-102.
Title: A common MSH2 mutation in English and North American HNPCC families: origin, phenotypic expression, and sex specific differences in colorectal cancer.
Author: Froggatt, N J|Green, J|Brassett, C|Evans, D G|Bishop, D T|Kolodner, R|Maher, E R
PMID: 10051005
Journal: Cancer Res. 1999 Mar 1;59(5):1090-5.
Title: Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.
Author: Fleisher, A S|Esteller, M|Wang, S|Tamura, G|Suzuki, H|Yin, J|Zou, T T|Abraham, J M|Kong, D|Smolinski, K N|Shi, Y Q|Rhyu, M G|Powell, S M|James, S P|Wilson, K T|Herman, J G|Meltzer, S J
PMID: 10070967
Journal: Virchows Arch. 1999 Jan;434(1):57-62.
Title: 5'-Cytosine DNA-methyltransferase mRNA levels in hereditary colon carcinoma.
Author: Jakob, C A|Guldenschuh, I|Hurlimann, R|Mullhaupt, B|Muller, A|Ammann, R|Fried, M|Roth, J
PMID: 10071236
Journal: Am J Gastroenterol. 1999 Mar;94(3):575-80.
Title: Colorectal cancer and the Muir-Torre syndrome in a Gypsy family: a review.
Author: Lynch, H T|Leibowitz, R|Smyrk, T|Fusaro, R M|Lynch, J F|Smith, A|Franklin, B|Stella, A|Liu, B
PMID: 10086635
Journal: Int J Cancer. 1999 Apr 12;81(2):214-8.
Title: Cancer risk in mutation carriers of DNA-mismatch-repair genes.
Author: Aarnio, M|Sankila, R|Pukkala, E|Salovaara, R|Aaltonen, L A|de la Chapelle, A|Peltomaki, P|Mecklin, J P|Jarvinen, H J
PMID: 10188721
Journal: Hum Genet. 1999 Feb;104(2):167-76.
Title: Family history characteristics, tumor microsatellite instability and germline MSH2 and MLH1 mutations in hereditary colorectal cancer.
Author: Bapat, B V|Madlensky, L|Temple, L K|Hiruki, T|Redston, M|Baron, D L|Xia, L|Marcus, V A|Soravia, C|Mitri, A|Shen, W|Gryfe, R|Berk, T|Chodirker, B N|Cohen, Z|Gallinger, S
PMID: 10190329
Journal: Hum Mol Genet. 1999 May;8(5):823-9.
Title: Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium.
Author: Millar, A L|Pal, T|Madlensky, L|Sherman, C|Temple, L|Mitri, A|Cheng, H|Marcus, V|Gallinger, S|Redston, M|Bapat, B|Narod, S
PMID: 10196371
Journal: Oncol Rep. 1999 May-Jun;6(3):497-505.
Title: Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer.
Author: Frazier, M L|Sinicrope, F A|Amos, C I|Cleary, K R|Lynch, P M|Levin, B|Luthra, R
PMID: 10203581
Journal: Dis Colon Rectum. 1999 Jan;42(1):1-9.
Title: A century of progress in hereditary nonpolyposis colorectal cancer (Lynch syndrome).
Author: Thorson, A G|Knezetic, J A|Lynch, H T
PMID: 10211513
Journal: Clin Cancer Res. 1999 Apr;5(4):937-41.
Title: Cooperation between p53 and hMLH1 in a human colocarcinoma cell line in response to DNA damage.
Author: Vikhanskaya, F|Colella, G|Valenti, M|Parodi, S|D'Incalci, M|Broggini, M
PMID: 10213232
Journal: Cancer Res. 1999 Apr 15;59(8):1840-5.
Title: The mismatch repair protein, hMLH1, mediates 5-substituted halogenated thymidine analogue cytotoxicity, DNA incorporation, and radiosensitization in human colon cancer cells.
Author: Berry, S E|Garces, C|Hwang, H S|Kunugi, K|Meyers, M|Davis, T W|Boothman, D A|Kinsella, T J
PMID: 10213489
Journal: Cancer Res. 1999 May 1;59(9):2029-33.
Title: Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression.
Author: Deng, G|Chen, A|Hong, J|Chae, H S|Kim, Y S
PMID: 10232580
Journal: Oncogene. 1999 Mar 25;18(12):2143-7.
Title: Mutated gene-specific phenotypes of dinucleotide repeat instability in human colorectal carcinoma cell lines deficient in DNA mismatch repair.
Author: Oki, E|Oda, S|Maehara, Y|Sugimachi, K
PMID: 10321739
Journal: Gut. 1999 Jun;44(6):839-43.
Title: Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer.
Author: Lamberti, C|Kruse, R|Ruelfs, C|Caspari, R|Wang, Y|Jungck, M|Mathiak, M|Malayeri, H R|Friedl, W|Sauerbruch, T|Propping, P
PMID: 10323887
Journal: Genes Chromosomes Cancer. 1999 Jun;25(2):75-81.
Title: Germline hMSH2 and differential somatic mutations in patients with Turcot's syndrome.
Author: Chan, T L|Yuen, S T|Chung, L P|Ho, J W|Kwan, K|Fan, Y W|Chan, A S|Leung, S Y
PMID: 10337989
Journal: Am J Prev Med. 1999 Feb;16(2):99-104.
Title: Public health perspectives on testing for colorectal cancer susceptibility genes.
Author: Coughlin, S S|Miller, D S
PMID: 10343885
Journal: Cancer Res. 1999 May 15;59(10):2302-6.
Title: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
Author: Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Danenberg, P V|Laird, P W
PMID: 10344733
Journal: Gastroenterology. 1999 Jun;116(6):1348-57.
Title: Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features.
Author: Yamamoto, H|Perez-Piteira, J|Yoshida, T|Terada, M|Itoh, F|Imai, K|Perucho, M
PMID: 10348818
Journal: Int J Cancer. 1999 Jun 11;81(6):902-10.
Title: Establishment and characterization of 12 human colorectal-carcinoma cell lines.
Author: Oh, J H|Ku, J L|Yoon, K A|Kwon, H J|Kim, W H|Park, H S|Yeo, K S|Song, S Y|Chung, J K|Park, J G
PMID: 10362137
Journal: Anticancer Res. 1999 Mar-Apr;19(2A):933-40.
Title: Immunocytochemical detection of hMSH2 and hMLH1 expression in oral SCC.
Author: Lo Muzio, L|Nocini, P|Mignogna, M D|Pannone, G|Staibano, S|Procaccini, M|Mariggio, M A|Dolci, M|De Rosa, G
PMID: 10368636
Journal: Gut. 1999 Jul;45(1):32-8.
Title: Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis.
Author: de Leon, M P|Pedroni, M|Benatti, P|Percesepe, A|Di Gregorio, C|Foroni, M|Rossi, G|Genuardi, M|Neri, G|Leonardi, F|Viel, A|Capozzi, E|Boiocchi, M|Roncucci, L
PMID: 10369701
Journal: Cancer. 1999 Jun 15;85(12):2512-8.
Title: Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer.
Author: Heinimann, K|Scott, R J|Buerstedde, J M|Weber, W|Siebold, K|Attenhofer, M|Muller, H|Dobbie, Z
PMID: 10375096
Journal: Dis Colon Rectum. 1999 Jun;42(6):710-5; discussion 715-6.
Title: Suspected hereditary nonpolyposis colorectal cancer: International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) criteria and results of genetic diagnosis.
Author: Park, J G|Vasen, H F|Park, K J|Peltomaki, P|Ponz de Leon, M|Rodriguez-Bigas, M A|Lubinski, J|Beck, N E|Bisgaard, M L|Miyaki, M|Wijnen, J T|Baba, S|Lynch, H T
PMID: 10378593
Journal: Dis Colon Rectum. 1999 Jun;42(6):722-6.
Title: Histologic comparison of hereditary nonpolyposis colorectal cancer associated with MSH2 and MLH1 and colorectal cancer from the general population.
Author: Shashidharan, M|Smyrk, T|Lin, K M|Ternent, C A|Thorson, A G|Blatchford, G J|Christensen, M A|Lynch, H T
PMID: 10378595
Journal: Ital J Gastroenterol Hepatol. 1999 Apr;31(3):218-22.
Title: Epidemiologic and genetic factor in colorectal cancer: development of cancer in dizygotic twins in a family with Lynch syndrome.
Author: Ponz de Leon, M|Pedroni, M|Benatti, P|Percesepe, A|Rossi, G|Genuardi, M|Roncucci, L
PMID: 10379484
Journal: Biochim Biophys Acta. 1999 May 31;1423(3):O1-O10.
Title: Molecular diagnostics of cancer predisposition: hereditary non-polyposis colorectal carcinoma and mismatch repair defects.
Author: Bocker, T|Ruschoff, J|Fishel, R
PMID: 10382540
Journal: JAMA. 1999 Jun 23-30;281(24):2316-20.
Title: Novel hMLH1 and hMSH2 germline mutations in African Americans with colorectal cancer.
Author: Weber, T K|Chin, H M|Rodriguez-Bigas, M|Keitz, B|Gilligan, R|O'Malley, L|Urf, E|Diba, N|Pazik, J|Petrelli, N J
PMID: 10386556
Journal: Ned Tijdschr Geneeskd. 1999 Jun 5;143(23):1201-6.
Title: [Genetics of colorectal cancer. I. Non-polyposis and polyposis forms of hereditary colorectal cancer].
Author: Menko, F H|Griffioen, G|Wijnen, J T|Tops, C M|Fodde, R|Vasen, H F
PMID: 10389534
Journal: Br J Cancer. 1999 Apr;80(1-2):11-6.
Title: Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours.
Author: Ghimenti, C|Tannergard, P|Wahlberg, S|Liu, T|Giulianotti, P G|Mosca, F|Fornaciari, G|Bevilacqua, G|Lindblom, A|Caligo, M A
PMID: 10389971
Journal: Int J Cancer. 1999 Aug 12;82(4):512-5.
Title: Predominant germ-line mutation of the hMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds.
Author: Bai, Y Q|Akiyama, Y|Nagasaki, H|Lu, S L|Arai, T|Morisaki, T|Kitamura, M|Muto, A|Nagashima, M|Nomizu, T|Iwama, T|Itoh, H|Baba, S|Iwai, T|Yuasa, Y
PMID: 10404063
Journal: Indian J Gastroenterol. 1999 Jul-Sep;18(3):118-21.
Title: Epidemiology of digestive tract cancers in India. V. Large and small bowel.
Author: Mohandas, K M|Desai, D C
PMID: 10407566
Journal: Br J Cancer. 1999 Jul;80(10):1569-70.
Title: Mutations in Bcl10 are very rare in colorectal cancer.
Author: Stone, J G|Rowan, A J|Tomlinson, I P|Houlston, R S
PMID: 10408399
Journal: Gan To Kagaku Ryoho. 1999 May;26(6):735-43.
Title: [Familial cancer: recent advances].
Author: Baba, S
PMID: 10410140
Journal: Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6.
Title: CpG island methylator phenotype in colorectal cancer.
Author: Toyota, M|Ahuja, N|Ohe-Toyota, M|Herman, J G|Baylin, S B|Issa, J P
PMID: 10411935
Journal: J Natl Cancer Inst. 1999 Jul 21;91(14):1221-6.
Title: Frequent microsatellite instability and mismatch repair gene mutations in young Chinese patients with colorectal cancer.
Author: Chan, T L|Yuen, S T|Chung, L P|Ho, J W|Kwan, K Y|Chan, A S|Ho, J C|Leung, S Y|Wyllie, A H
PMID: 10413423
Journal: Curr Opin Oncol. 1999 Jul;11(4):305-11.
Title: Screening for colorectal cancer and other GI cancers.
Author: Scotiniotis, I|Lewis, J D|Strom, B L
PMID: 10416884
Journal: Lab Invest. 1999 Jul;79(7):903-9.
Title: Correlation of methylation of the hMLH1 promoter with lack of expression of hMLH1 in sporadic gastric carcinomas with replication error.
Author: Kang, G H|Shim, Y H|Ro, J Y
PMID: 10418831
Journal: J Pathol. 1999 Jul;188(3):252-7.
Title: BAT-26 identifies sporadic colorectal cancers with mutator phenotype: a correlative study with clinico-pathological features and mutations in mismatch repair genes.
Author: Cravo, M|Lage, P|Albuquerque, C|Chaves, P|Claro, I|Gomes, T|Gaspar, C|Fidalgo, P|Soares, J|Nobre-Leitao, C
PMID: 10419591
Journal: Gastroenterology. 1999 Aug;117(2):350-8.
Title: Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers.
Author: Sinicrope, F A|Lemoine, M|Xi, L|Lynch, P M|Cleary, K R|Shen, Y|Frazier, M L
PMID: 10419916
Journal: Cancer Genet Cytogenet. 1999 Jul 1;112(1):2-8.
Title: Microsatellite instability and expression of MLH1 and MSH2 in normal and malignant endometrial and ovarian epithelium in hereditary nonpolyposis colorectal cancer family members.
Author: Ichikawa, Y|Lemon, S J|Wang, S|Franklin, B|Watson, P|Knezetic, J A|Bewtra, C|Lynch, H T
PMID: 10432927
Journal: J Gastroenterol. 1999 Jun;34(3):341-4.
Title: Rectal cancer in a 13-year-old boy without a detectable germline mutation in FAP and HNPCC genes.
Author: Kashiwagi, H|Senba, S|Konishi, F|Konishi, M|Miyaki, M|Shoji, M|Kanazawa, K
PMID: 10433009
Journal: Gut. 1999 Sep;45(3):409-15.
Title: Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair.
Author: Cawkwell, L|Gray, S|Murgatroyd, H|Sutherland, F|Haine, L|Longfellow, M|O'Loughlin, S|Cross, D|Kronborg, O|Fenger, C|Mapstone, N|Dixon, M|Quirke, P
PMID: 10446111
Journal: Eur J Cancer. 1999 Feb;35(2):289-95.
Title: Evaluation of the replication error phenotype in relation to molecular and clinicopathological features in hereditary and early onset colorectal cancer.
Author: Capozzi, E|Della Puppa, L|Fornasarig, M|Pedroni, M|Boiocchi, M|Viel, A
PMID: 10448273
Journal: Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10296-301.
Title: Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.
Author: Wheeler, J M|Beck, N E|Kim, H C|Tomlinson, I P|Mortensen, N J|Bodmer, W F
PMID: 10468602
Journal: Anticancer Res. 1999 May-Jun;19(3A):1821-6.
Title: Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables.
Author: Johannsdottir, J T|Bergthorsson, J T|Gretarsdottir, S|Kristjansson, A K|Ragnarsson, G|Jonasson, J G|Egilsson, V|Ingvarsson, S
PMID: 10470121
Journal: Biochem Biophys Res Commun. 1999 Sep 7;262(3):671-6.
Title: DNA methylation analysis using bisulfite treatment and PCR-single-strand conformation polymorphism in colorectal cancer showing microsatellite instability.
Author: Maekawa, M|Sugano, K|Kashiwabara, H|Ushiama, M|Fujita, S|Yoshimori, M|Kakizoe, T
PMID: 10471384
Journal: Int J Cancer. 1999 Oct 8;83(2):197-202.
Title: hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden.
Author: Planck, M|Koul, A|Fernebro, E|Borg, A|Kristoffersson, U|Olsson, H|Wenngren, E|Mangell, P|Nilbert, M
PMID: 10471527
Journal: Hum Genet. 1999 Jul-Aug;105(1-2):79-85.
Title: Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.
Author: Wang, Q|Lasset, C|Desseigne, F|Saurin, J C|Maugard, C|Navarro, C|Ruano, E|Descos, L|Trillet-Lenoir, V|Bosset, J F|Puisieux, A
PMID: 10480359
Journal: Int J Cancer. 1999 Oct 29;83(3):309-13.
Title: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer.
Author: Suzuki, H|Itoh, F|Toyota, M|Kikuchi, T|Kakiuchi, H|Hinoda, Y|Imai, K
PMID: 10495421
Journal: Genet Test. 1999;3(3):259-64.
Title: Various mutation screening techniques in the DNA mismatch repair genes hMSH2 and hMLH1.
Author: Wahlberg, S|Liu, T|Lindblom, P|Lindblom, A
PMID: 10495924
Journal: Lab Invest. 1999 Sep;79(9):1145-50.
Title: Microsatellite alterations in serum DNA of patients with colorectal cancer.
Author: Kolble, K|Ullrich, O M|Pidde, H|Barthel, B|Diermann, J|Rudolph, B|Dietel, M|Schlag, P M|Scherneck, S
PMID: 10496533
Journal: Oncogene. 1999 Sep 20;18(38):5325-33.
Title: Mouse models for colorectal cancer.
Author: Heyer, J|Yang, K|Lipkin, M|Edelmann, W|Kucherlapati, R
PMID: 10498885
Journal: J Med Genet. 1999 Sep;36(9):678-82.
Title: Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer.
Author: Verma, L|Kane, M F|Brassett, C|Schmeits, J|Evans, D G|Kolodner, R D|Maher, E R
PMID: 10507723
Journal: Mol Cell Biol. 1999 Nov;19(11):7558-67.
Title: Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination.
Author: Studamire, B|Price, G|Sugawara, N|Haber, J E|Alani, E
PMID: 10523644
Journal: Am J Surg Pathol. 1999 Oct;23(10):1248-55.
Title: Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors.
Author: Marcus, V A|Madlensky, L|Gryfe, R|Kim, H|So, K|Millar, A|Temple, L K|Hsieh, E|Hiruki, T|Narod, S|Bapat, B V|Gallinger, S|Redston, M
PMID: 10524526
Journal: Eur J Cancer. 1999 Jun;35(6):942-5.
Title: Microsatellite instability is rare in rectal carcinomas and signifies hereditary cancer.
Author: Nilbert, M|Planck, M|Fernebro, E|Borg, A|Johnson, A
PMID: 10533476
Journal: Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12661-6.
Title: Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers.
Author: Kuismanen, S A|Holmberg, M T|Salovaara, R|Schweizer, P|Aaltonen, L A|de La Chapelle, A|Nystrom-Lahti, M|Peltomaki, P
PMID: 10535979
Journal: Cancer Res. 1999 Oct 15;59(20):5068-74.
Title: Germ-line msh6 mutations in colorectal cancer families.
Author: Kolodner, R D|Tytell, J D|Schmeits, J L|Kane, M F|Gupta, R D|Weger, J|Wahlberg, S|Fox, E A|Peel, D|Ziogas, A|Garber, J E|Syngal, S|Anton-Culver, H|Li, F P
PMID: 10537275
Journal: Clin Cancer Res. 1999 Oct;5(10):2908-17.
Title: Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
Author: Liu, L|Taverna, P|Whitacre, C M|Chatterjee, S|Gerson, S L
PMID: 10537360
Journal: J Biol Chem. 1999 Nov 5;274(45):32368-75.
Title: Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.
Author: Raschle, M|Marra, G|Nystrom-Lahti, M|Schar, P|Jiricny, J
PMID: 10542278
Journal: J Med Genet. 1999 Nov;36(11):801-18.
Title: Genetic susceptibility to non-polyposis colorectal cancer.
Author: Lynch, H T|de la Chapelle, A
PMID: 10544223
Journal: J Med Genet. 1999 Nov;36(11):819-22.
Title: Strategies for screening for hereditary non-polyposis colorectal cancer.
Author: Loukola, A|de la Chapelle, A|Aaltonen, L A
PMID: 10544224
Journal: Semin Cancer Biol. 1999 Oct;9(5):349-57.
Title: CpG island methylator phenotypes in aging and cancer.
Author: Toyota, M|Issa, J P
PMID: 10547343
Journal: Cancer Res. 1999 Nov 1;59(21):5438-42.
Title: Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.
Author: Toyota, M|Ahuja, N|Suzuki, H|Itoh, F|Ohe-Toyota, M|Imai, K|Baylin, S B|Issa, J P
PMID: 10554013
Journal: Bull Cancer. 1999 Oct;86(10):812-4.
Title: [HNPCC syndrome, microsatellite instability and NF1 gene alteration].
Author: Puisieux, A
PMID: 10572231
Journal: Eur J Hum Genet. 1999 Oct-Nov;7(7):778-82.
Title: Assessment of pathogenicity criteria for constitutional missense mutations of the hereditary nonpolyposis colorectal cancer genes MLH1 and MSH2.
Author: Genuardi, M|Carrara, S|Anti, M|Ponz de Leon, M|Viel, A
PMID: 10573010
Journal: Ann Acad Med Singapore. 1999 May;28(3):323-9.
Title: 1998 Runme Shaw Memorial Lecture: somatic evolution of cancer.
Author: Bodmer, W F
PMID: 10575514
Journal: Ital J Gastroenterol Hepatol. 1999 Aug-Sep;31(6):476-80.
Title: Clinical and molecular diagnosis of hereditary non-polyposis colorectal cancer: problems and pitfalls in an extended pedigree.
Author: Ponz de Leon, M|Benatti, P|Percesepe, A|Rossi, G|Viel, A|Santarosa, M|Pedroni, M|Roncucci, L
PMID: 10575566
Journal: J Med Genet. 1999 Dec;36(12):919-21.
Title: A proven de novo germline mutation in HNPCC.
Author: Kraus, C|Kastl, S|Gunther, K|Klessinger, S|Hohenberger, W|Ballhausen, W G
PMID: 10594000
Journal: Clin Chem Lab Med. 1999 Sep;37(9):883-7.
Title: Quantitative differences between aberrant transcripts which occur as common isoforms and due to mutation-based exon skipping of the mismatch repair gene hMLH1.
Author: Plaschke, J|Bulitta, C|Saeger, H D|Schackert, H K
PMID: 10596954
Journal: Hum Genet. 1999 Nov;105(5):437-41.
Title: Missense mutations in hMLH1 associated with colorectal cancer.
Author: Liu, T|Tannergard, P|Hackman, P|Rubio, C|Kressner, U|Lindmark, G|Hellgren, D|Lambert, B|Lindblom, A
PMID: 10598809
Journal: Ugeskr Laeger. 1999 Nov 8;161(45):6174-8.
Title: [Registration of hereditary non-polyposis colorectal cancer].
Author: Bernstein, I T|Bisgaard, M L|Myrhoj, T
PMID: 10603753
Journal: Hepatogastroenterology. 1999 Nov-Dec;46(30):3115-20.
Title: Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability.
Author: Komura, K|Masuda, H|Esumi, M
PMID: 10626171
Journal: Cancer. 1999 Dec 1;86(11 Suppl):2457-63.
Title: Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer. Part II: Hereditary nonpolyposis colorectal carcinoma as a model.
Author: Lynch, H T|Watson, P|Shaw, T G|Lynch, J F|Harty, A E|Franklin, B A|Kapler, C R|Tinley, S T|Liu, B|Lerman, C
PMID: 10630171
Journal: Cancer. 1999 Dec 1;86(11 Suppl):2540-50.
Title: Genetic testing and counseling for hereditary forms of colorectal cancer.
Author: Petersen, G M|Brensinger, J D|Johnson, K A|Giardiello, F M
PMID: 10630180
Journal: Schweiz Med Wochenschr. 1999 Dec 18;129(50):1978-85.
Title: [Identification and genetic counseling of people with HNPCC (hereditary nonpolyposis colorectal cancer): old and new research goals].
Author: Muller, H|Dobbie, Z|Heinimann, K
PMID: 10637951
Journal: Int J Colorectal Dis. 1999 Nov;14(4-5):194-200.
Title: Towards a molecular classification of colorectal cancer.
Author: Jass, J R
PMID: 10647627
Journal: Tumori. 1999 Sep-Oct;85(5):387-90.
Title: The prevalence of colorectal cancer in Italy.
Author: Gatta, G|Francisci, S|Ponz de Leon, M
PMID: 10665855
Journal: Eur J Cancer. 1999 Nov;35(12):1724-9.
Title: Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Author: Ku, J L|Yoon, K A|Kim, D Y|Park, J G
PMID: 10674020
Journal: Adv Exp Med Biol. 1999;470:99-104.
Title: Familial association.
Author: Burt, R W
PMID: 10709679
Journal: Verh Dtsch Ges Pathol. 1999;83:240-6.
Title: [Aspirin suppresses microsatellite instability].
Author: Wallinger, S|Dietmaier, W|Beyser, K|Bocker, T|Hofstadter, F|Fishel, R|Ruschoff, J
PMID: 10714217
Journal: Eur J Cancer Prev. 1999 Dec;8 Suppl 1:S33-7.
Title: Germline mutation and genome instability.
Author: Olschwang, S
PMID: 10772416
Journal: Zhonghua Zhong Liu Za Zhi. 1999 Mar;21(2):105-7.
Title: [Mutation of human mismatch repair genes in hereditary nonpolyposis colorectal cancer (HNPCC) families].
Author: Yuan, Y|Huang, J|Zheng, S
PMID: 11776847
Journal: Genes Chromosomes Cancer. 2000 Jan;27(1):17-25.
Title: Microsatellite instability as a predictor of a mutation in a DNA mismatch repair gene in familial colorectal cancer.
Author: Liu, T|Wahlberg, S|Burek, E|Lindblom, P|Rubio, C|Lindblom, A
PMID: 10564582
Journal: Oncol Rep. 2000 Jan-Feb;7(1):39-43.
Title: Microsatellite instability and MLH1 and MSH2 germline defects are related to clinicopathological features in sporadic colorectal cancer.
Author: Fornasarig, M|Viel, A|Valentini, M|Capozzi, E|Sigon, R|De Paoli, A|Della Puppa, L|Boiocchi, M
PMID: 10601588
Journal: Hum Mutat. 2000 Jan;15(1):116.
Title: Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families.
Author: Isidro, G|Veiga, I|Matos, P|Almeida, S|Bizarro, S|Marshall, B|Baptista, M|Leite, J|Regateiro, F|Soares, J|Castedo, S|Boavida, M G
PMID: 10612836
Journal: Nat Genet. 2000 Jan;24(1):27-35.
Title: MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.
Author: Lipkin, S M|Wang, V|Jacoby, R|Banerjee-Basu, S|Baxevanis, A D|Lynch, H T|Elliott, R M|Collins, F S
PMID: 10615123
Journal: Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):710-5.
Title: Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype.
Author: Toyota, M|Ohe-Toyota, M|Ahuja, N|Issa, J P
PMID: 10639144
Journal: Gut. 2000 Mar;46(3):367-9.
Title: Defective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers.
Author: Cawkwell, L|Sutherland, F|Murgatroyd, H|Jarvis, P|Gray, S|Cross, D|Shepherd, N|Day, D|Quirke, P
PMID: 10673298
Journal: Int J Cancer. 2000 Mar 1;85(5):606-13.
Title: Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer.
Author: Plaschke, J|Kruppa, C|Tischler, R|Bocker, T|Pistorius, S|Dralle, H|Ruschoff, J|Saeger, H D|Fishel, R|Schackert, H K
PMID: 10699937
Journal: Int J Cancer. 2000 Mar 15;85(6):796-800.
Title: Germline BRCA1 and HMLH1 mutations in a family with male and female breast carcinoma.
Author: Borg, A|Isola, J|Chen, J|Rubio, C|Johansson, U|Werelius, B|Lindblom, A
PMID: 10709098
Journal: Eur J Hum Genet. 2000 Jan;8(1):49-53.
Title: Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach.
Author: Fidalgo, P|Almeida, M R|West, S|Gaspar, C|Maia, L|Wijnen, J|Albuquerque, C|Curtis, A|Cravo, M|Fodde, R|Leitao, C N|Burn, J
PMID: 10713887
Journal: Int J Cancer. 2000 Jan 20;89(1):87-91.
Title: Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition.
Author: Calistri, D|Presciuttini, S|Buonsanti, G|Radice, P|Gazzoli, I|Pensotti, V|Sala, P|Eboli, M|Andreola, S|Russo, A|Pierotti, M|Bertario, L|Ranzani, G N
PMID: 10719736
Journal: Toxicol Lett. 2000 Mar 15;112-113:239-44.
Title: Mutator phenotype due to loss of heterozygosity in diploid yeast strains with mutations in MSH2 and MLH1.
Author: Drotschmann, K|Shcherbakova, P V|Kunkel, T A
PMID: 10720737
Journal: Adv Anat Pathol. 2000 Mar;7(2):85-93.
Title: Mismatch repair proteins and microsatellites hit clinical practice.
Author: Stahl, J
PMID: 10721415
Journal: Int J Cancer. 2000 Apr 1;86(1):60-6.
Title: Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology.
Author: Parc, Y R|Halling, K C|Burgart, L J|McDonnell, S K|Schaid, D J|Thibodeau, S N|Halling, A C
PMID: 10728595
Journal: Br J Cancer. 2000 Feb;82(4):871-80.
Title: Extensive molecular screening for hereditary non-polyposis colorectal cancer.
Author: Dieumegard, B|Grandjouan, S|Sabourin, J C|Le Bihan, M L|Lefrere, I|Bellefqih|Pignon, J P|Rougier, P|Lasser, P|Benard, J|Couturier, D|Bressac-de Paillerets, B
PMID: 10732761
Journal: Dis Colon Rectum. 2000 Mar;43(3):353-60; discussion 360-2.
Title: Hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay.
Author: Sarroca, C|Alfano, N|Bendin, G T|Della Valle, A|Dominguez, A|Quadrelli, R|Vaglio, A|Mechoso, B|Tinley, S T|Harty, A E|Lynch, J F|Franklin, B A|Kristo, P|Smyrk, T C|Peltomaki, P|Lynch, H T
PMID: 10733117
Journal: Nucleic Acids Res. 2000 Apr 15;28(8):E32.
Title: MethyLight: a high-throughput assay to measure DNA methylation.
Author: Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Blake, C|Shibata, D|Danenberg, P V|Laird, P W
PMID: 10734209
Journal: Gynecol Oncol. 2000 Apr;77(1):18-25.
Title: Atypical clustering of gynecologic malignancies: A family study including molecular analysis of candidate genes.
Author: Cohn, D E|Babb, S|Whelan, A J|Mutch, D G|Herzog, T J|Rader, J S|Elbendary, A|Goodfellow, P J
PMID: 10739686
Journal: Eur J Cancer. 2000 Jan;36(1):49-54.
Title: Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancer.
Author: Debniak, T|Kurzawski, G|Gorski, B|Kladny, J|Domagala, W|Lubinski, J
PMID: 10741294
Journal: J Biol Chem. 2000 May 26;275(21):15728-32.
Title: Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells.
Author: Leung, W K|Kim, J J|Wu, L|Sepulveda, J L|Sepulveda, A R
PMID: 10748105
Journal: J Biol Chem. 2000 Jun 9;275(23):17808-13.
Title: Identification of mismatch repair protein complexes in HeLa nuclear extracts and their interaction with heteroduplex DNA.
Author: Matton, N|Simonetti, J|Williams, K
PMID: 10748159
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2000 Apr;17(2):82-6.
Title: [One of the etiological factors of digestive tract cancers in Chinese: the missense mutation Val384Asp in the hMLH1 gene].
Author: Wang, Y|Zhou, J|Li, Z|Wang, J|Li, J|Gao, C|Gao, P
PMID: 10751526
Journal: Curr Opin Genet Dev. 2000 Apr;10(2):157-61.
Title: Mismatch repair defects in cancer.
Author: Jiricny, J|Nystrom-Lahti, M
PMID: 10753784
Journal: Br J Cancer. 2000 Apr;82(7):1276-82.
Title: Genetic analysis of multiple synchronous lesions of the colon adenoma-carcinoma sequence.
Author: Sedivy, R|Wolf, B|Kalipciyan, M|Steger, G G|Karner-Hanusch, J|Mader, R M
PMID: 10755401
Journal: Am J Med Genet. 2000 Mar 20;91(3):207-11.
Title: Response to genetic counseling and testing for the APC I1307K mutation.
Author: Johnson, K A|Rosenblum-Vos, L|Petersen, G M|Brensinger, J D|Giardiello, F M|Griffin, C A
PMID: 10756345
Journal: J Cell Biochem Suppl. 2000;34:23-7.
Title: Implications of low COX-2 expression in colorectal neoplasms with defective DNA mismatch repair.
Author: Karnes, W E Jr
PMID: 10762011
Journal: Oncogene. 2000 Mar 23;19(13):1719-23.
Title: Evidence for a recessive inheritance of Turcot's syndrome caused by compound heterozygous mutations within the PMS2 gene.
Author: De Rosa, M|Fasano, C|Panariello, L|Scarano, M I|Belli, G|Iannelli, A|Ciciliano, F|Izzo, P
PMID: 10763829
Journal: Anticancer Res. 2000 Jan-Feb;20(1A):171-5.
Title: Immunohistochemical and DNA sequencing analysis on human mismatch repair gene MLH1 in cervical squamous cell carcinoma with LOH of this gene.
Author: Hu, X|Guo, Z|Pang, T|Li, Q|Afink, G|Ponten, J
PMID: 10769651
Journal: Cancer Res. 2000 Apr 15;60(8):2225-31.
Title: HMSH6 alterations in patients with microsatellite instability-low colorectal cancer.
Author: Parc, Y R|Halling, K C|Wang, L|Christensen, E R|Cunningham, J M|French, A J|Burgart, L J|Price-Troska, T L|Roche, P C|Thibodeau, S N
PMID: 10786688
Journal: Am J Pathol. 2000 May;156(5):1773-9.
Title: Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers.
Author: Kuismanen, S A|Holmberg, M T|Salovaara, R|de la Chapelle, A|Peltomaki, P
PMID: 10793088
Journal: Semin Surg Oncol. 2000 Jun;18(4):305-13.
Title: Hereditary nonpolyposis colorectal cancer.
Author: Lynch, H T|Lynch, J F
PMID: 10805952
Journal: G Chir. 2000 Apr;21(4):177-87.
Title: [Hereditary nonpolyposis colorectal cancer (Lynch syndrome): a review of the literature and case reports].
Author: Lucci, S|Pasta, V|Arcieri, S|Rivolta, R|Candioli, S|Manigrasso, A|Papetti, M T|Cerutti, L|Merlino, G
PMID: 10812774
Journal: Oncogene. 2000 Apr 27;19(18):2249-56.
Title: Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability.
Author: Ma, A H|Xia, L|Littman, S J|Swinler, S|Lader, G|Polinkovsky, A|Olechnowicz, J|Kasturi, L|Lutterbaugh, J|Modrich, P|Veigl, M L|Markowitz, S D|Sedwick, W D
PMID: 10822375
Journal: Mod Pathol. 2000 May;13(5):586-90.
Title: Association of a duodenal follicular lymphoma and hereditary nonpolyposis colorectal cancer.
Author: Rosty, C|Briere, J|Cellier, C|Delabesse, E|Carnot, F|Barbier, J P|Laurent-Puig, P
PMID: 10824932
Journal: J Clin Oncol. 2000 Jun;18(11):2193-200.
Title: Population-based molecular detection of hereditary nonpolyposis colorectal cancer.
Author: Salovaara, R|Loukola, A|Kristo, P|Kaariainen, H|Ahtola, H|Eskelinen, M|Harkonen, N|Julkunen, R|Kangas, E|Ojala, S|Tulikoura, J|Valkamo, E|Jarvinen, H|Mecklin, J P|Aaltonen, L A|de la Chapelle, A
PMID: 10829038
Journal: Med J Aust. 2000 Apr 3;172(7):313-6.
Title: Value of predictive genetic testing in management of hereditary non-polyposis colorectal cancer (HNPCC)
Author: Stanley, A J|Gaff, C L|Aittomaki, A K|Fabre, L C|Macrae, F A|St John, J
PMID: 10844916
Journal: Oncogene. 2000 May 25;19(23):2774-9.
Title: Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice.
Author: Shoemaker, A R|Haigis, K M|Baker, S M|Dudley, S|Liskay, R M|Dove, W F
PMID: 10851078
Journal: Eur J Hum Genet. 2000 May;8(5):347-52.
Title: Cell type specificity in alternative splicing of the human mismatch repair gene hMSH2.
Author: Clarke, L A|Jordan, P|Boavida, M G
PMID: 10854094
Journal: Acta Oncol. 2000;39(2):189-93.
Title: Health, life and disability insurance and hereditary risk for breast or colorectal cancer.
Author: Norum, J|Tranebjaerg, L
PMID: 10859009
Journal: Gut. 2000 Jul;47(1):37-42.
Title: DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
Author: Iino, H|Simms, L|Young, J|Arnold, J|Winship, I M|Webb, S I|Furlong, K L|Leggett, B|Jass, J R
PMID: 10861262
Journal: Gut. 2000 Jul;47(1):43-9.
Title: Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
Author: Jass, J R|Iino, H|Ruszkiewicz, A|Painter, D|Solomon, M J|Koorey, D J|Cohn, D|Furlong, K L|Walsh, M D|Palazzo, J|Edmonston, T B|Fishel, R|Young, J|Leggett, B A
PMID: 10861263
Journal: Int J Cancer. 2000 Jul 15;87(2):200-3.
Title: Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability.
Author: Bevilacqua, R A|Simpson, A J
PMID: 10861474
Journal: Hum Mutat. 2000 Jul;16(1):91-2.
Title: Novel germline mutation (300-305delAGTTGA) in the human MSH2 gene in hereditary non-polyposis colorectal cancer (HNPCC).
Author: Glasl, S|Papatheodorou, L|Baretton, G|Jung, C|Gross, M
PMID: 10874318
Journal: Gut. 2000 Aug;47(2):262-7.
Title: The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.
Author: Kim, H C|Wheeler, J M|Kim, J C|Ilyas, M|Beck, N E|Kim, B S|Park, K C|Bodmer, W F
PMID: 10896919
Journal: Bull Cancer. 2000 Jun;87(6):455-61.
Title: [Update on gastroenterology].
Author: Ychou, M|Senesse, P|Quenet, F
PMID: 10903787
Journal: Ann N Y Acad Sci. 2000 Jun;910:50-9; discussion 59-61.
Title: Molecular genetics of hereditary nonpolyposis colorectal cancer.
Author: Boland, C R
PMID: 10911905
Journal: Ann N Y Acad Sci. 2000 Jun;910:62-73; discussion 73-4.
Title: Pathology of hereditary nonpolyposis colorectal cancer.
Author: Jass, J R
PMID: 10911906
Journal: Ann N Y Acad Sci. 2000 Jun;910:140-53; discussion 153-5.
Title: The epigenetics of colorectal cancer.
Author: Issa, J P
PMID: 10911911
Journal: J Pathol. 2000 Aug;191(4):355-60.
Title: Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype.
Author: Chaves, P|Cruz, C|Lage, P|Claro, I|Cravo, M|Leitao, C N|Soares, J
PMID: 10918209
Journal: J Med Genet. 2000 Aug;37(8):588-92.
Title: The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers.
Author: Wheeler, J M|Loukola, A|Aaltonen, L A|Mortensen, N J|Bodmer, W F
PMID: 10922385
Journal: Am J Pathol. 2000 Aug;157(2):347-52.
Title: Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer.
Author: Loukola, A|Vilkki, S|Singh, J|Launonen, V|Aaltonen, L A
PMID: 10934138
Journal: Int J Oncol. 2000 Sep;17(3):467-71.
Title: Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer.
Author: Takama, F|Kanuma, T|Wang, D|Nishida, J I|Nakabeppu, Y|Wake, N|Mizunuma, H
PMID: 10938385
Journal: Am J Gastroenterol. 2000 Aug;95(8):2110-5.
Title: Problems in the identification of hereditary nonpolyposis colorectal cancer in two families with late development of full-blown clinical spectrum.
Author: de Leon, M P|Benatti, P|Pedroni, M|Viel, A|Genuardi, M|Percesepe, A|Roncucci, L
PMID: 10950068
Journal: Gastroenterology. 2000 Aug;119(2):598.
Title: Late onset and high incidence of colon cancer of the mutator phenotype with hypermethylated hMLH1 gene in women.
Author: Malkhosyan, S R|Yamamoto, H|Piao, Z|Perucho, M
PMID: 10960275
Journal: Gut. 2000 Aug;47(2):315-6.
Title: hMLH1 and hMSH2 immunostaining in colorectal cancer.
Author: Jass, J R
PMID: 10960281
Journal: J Surg Oncol. 2000 Aug;74(4):249-56.
Title: Genetic alterations of sporadic colorectal cancer with microsatellite instability, especially characteristics of primary multiple colorectal cancers.
Author: Abe, Y|Masuda, H
PMID: 10962455
Journal: Medicina (B Aires). 2000;60(2):188-94.
Title: [Diagnosis by directed mutagenesis of a mutation at the hMSH2 gene associated with hereditary nonpolyposis colorectal cancer].
Author: Roque, M|Pusiol, E|Giribet, G|Perinetti, H|Mayorga, L S
PMID: 10962807
Journal: J Med Genet. 2000 Sep;37(9):641-5.
Title: Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1.
Author: Syngal, S|Fox, E A|Eng, C|Kolodner, R D|Garber, J E
PMID: 10978352
Journal: S Afr Med J. 2000 Jul;90(7):709-14.
Title: Molecular genetics improves the management of hereditary non-polyposis colorectal cancer.
Author: Ramesar, R S|Madden, M V|Felix, R|Harocopos, C J|Westbrook, C A|Jones, G|Cruse, J P|Goldberg, P A
PMID: 10985134
Journal: Cancer Res. 2000 Sep 1;60(17):4864-8.
Title: Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1.
Author: Fleisher, A S|Esteller, M|Harpaz, N|Leytin, A|Rashid, A|Xu, Y|Liang, J|Stine, O C|Yin, J|Zou, T T|Abraham, J M|Kong, D|Wilson, K T|James, S P|Herman, J G|Meltzer, S J
PMID: 10987299
Journal: J Clin Gastroenterol. 2000 Sep;31(2):114-20.
Title: Families at risk for colorectal cancer: risk assessment and genetic testing.
Author: Schoen, R E
PMID: 10993425
Journal: Int J Cancer. 2000 Aug 20;90(4):175-85.
Title: Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency.
Author: Kennedy, A S|Harrison, G H|Mansfield, C M|Zhou, X J|Xu, J F|Balcer-Kubiczek, E K
PMID: 10993958
Journal: J Natl Cancer Inst. 2000 Sep 20;92(18):1517-22.
Title: Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases.
Author: Peel, D J|Ziogas, A|Fox, E A|Gildea, M|Laham, B|Clements, E|Kolodner, R D|Anton-Culver, H
PMID: 10995807
Journal: Histopathology. 2000 Oct;37(4):295-301.
Title: Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum.
Author: Jass, J R|Young, J|Leggett, B A
PMID: 11012735
Journal: Clin Cancer Res. 2000 Oct;6(10):3827-31.
Title: Antisense inhibition of hMLH1 is not sufficient for loss of DNA mismatch repair function in the HCT116+chromosome 3 cell line.
Author: Chauhan, D P|Yang, Q|Carethers, J M|Marra, G|Chang, C L|Chamberlain, S M|Boland, C R
PMID: 11051225
Journal: J Pathol. 2000 Nov;192(3):328-35.
Title: Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients.
Author: de Leeuw, W J|Dierssen, J|Vasen, H F|Wijnen, J T|Kenter, G G|Meijers-Heijboer, H|Brocker-Vriends, A|Stormorken, A|Moller, P|Menko, F|Cornelisse, C J|Morreau, H
PMID: 11054716
Journal: J Clin Oncol. 2000 Nov 1;18(21 Suppl):19S-31S.
Title: Lynch syndrome: genetics, natural history, genetic counseling, and prevention.
Author: Lynch, H T|Lynch, J
PMID: 11060321
Journal: J Gastroenterol. 2000;35(10):727-34.
Title: DNA methylation and gastrointestinal malignancies: functional consequences and clinical implications.
Author: Toyota, M|Itoh, F|Imai, K
PMID: 11063215
Journal: Genes Chromosomes Cancer. 2000 Dec;29(4):367-70.
Title: Pathological exon skipping in an HNPCC proband with MLH1 splice acceptor site mutation.
Author: Clarke, L A|Veiga, I|Isidro, G|Jordan, P|Ramos, J S|Castedo, S|Boavida, M G
PMID: 11066084
Journal: Br J Dermatol. 2000 Oct;143(4):851-5.
Title: Hereditary non-polyposis colorectal cancer associated with disseminated superficial porokeratosis. Microsatellite instability in skin tumours.
Author: Takata, M|Shirasaki, F|Nakatani, T|Takehara, K
PMID: 11069471
Journal: Ann Chir Gynaecol. 2000;89(3):207-10.
Title: Surveillance on mutation carriers of DNA mismatch repair genes.
Author: Jarvinen, H J|Aarnio, M
PMID: 11079789
Journal: Gastroenterol Clin Biol. 2000 Oct;24(10):917-22.
Title: [Response of metastatic colorectal cancers to treatment with CPT11 (irinotecan): implications of the mismatched base repair system].
Author: Fallik, D|Sabourin, J C|Borrini, F|Jacob, S|Boige, V|Praz, F|Ducreux, M
PMID: 11084429
Journal: Int J Cancer. 2000 Dec 15;88(6):928-31.
Title: A polymorphism in the ATM gene modulates the penetrance of hereditary non-polyposis colorectal cancer.
Author: Maillet, P|Chappuis, P O|Vaudan, G|Dobbie, Z|Muller, H|Hutter, P|Sappino, A P
PMID: 11093816
Journal: Br J Cancer. 2000 Dec;83(12):1643-5.
Title: Population carrier frequency of hMSH2 and hMLH1 mutations.
Author: Dunlop, M G|Farrington, S M|Nicholl, I|Aaltonen, L|Petersen, G|Porteous, M|Carothers, A
PMID: 11104559
Journal: Comb Chem High Throughput Screen. 2000 Dec;3(6):519-24.
Title: High throughput genetic screening for the detection of hereditary non-polyposis colon cancer (HNPCC) using capillary electrophoresis.
Author: Merkelbach-Bruse, S|Kose, S|Losen, I|Bosserhoff, A K|Buettner, R
PMID: 11121520
Journal: J Clin Pathol. 2000 Nov;53(11):841-5.
Title: Pathogenesis of non-familial colorectal carcinomas with high microsatellite instability.
Author: Shitoh, K|Konishi, F|Miyaki, M|Iijima, T|Furukawa, T|Tsukamoto, T|Nagai, H
PMID: 11127266
Journal: Hum Pathol. 2000 Dec;31(12):1506-14.
Title: Colorectal carcinomas with high microsatellite instability: defining a distinct immunologic and molecular entity with respect to prognostic markers.
Author: Edmonston, T B|Cuesta, K H|Burkholder, S|Barusevicius, A|Rose, D|Kovatich, A J|Boman, B|Fry, R|Fishel, R|Palazzo, J P
PMID: 11150376
Journal: Hum Pathol. 2000 Dec;31(12):1522-7.
Title: Adrenocortical adenocarcinoma in an MSH2 carrier: coincidence or causal relation?
Author: Berends, M J|Cats, A|Hollema, H|Karrenbeld, A|Beentjes, J A|Sijmons, R H|Mensink, R G|Hofstra, R M|Verschueren, R C|Kleibeuker, J H
PMID: 11150379
Journal: Hum Genet. 2000 Dec;107(6):623-9.
Title: Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium?
Author: Charames, G S|Millar, A L|Pal, T|Narod, S|Bapat, B
PMID: 11153917
Journal: Anticancer Res. 2000 Nov-Dec;20(6C):4727-32.
Title: Mismatch repair deficiency in sporadic synchronous colorectal cancer.
Author: Brueckl, W M|Limmert, T|Brabletz, T|Guenther, K|Jung, A|Hermann, K|Wiest, G H|Kirchner, T|Hohenberger, W|Hahn, E G|Wein, A
PMID: 11205208
Journal: Prog Urol. 2000 Dec;10(6):1204-7.
Title: [Urothelial tumor and colonic cancer in the context of a syndrome of hereditary predisposition to HNPCC colonic cancer].
Author: de la Taille, A|Mariette, C|Buisine, M P|Biserte, J|Triboulet, J P
PMID: 11217560
Journal: Tumori. 2000 Nov-Dec;86(6):439-44.
Title: Low incidence of hereditary nonpolyposis colorectal cancer syndrome in a selected area of the Lombardy Cancer Registry.
Author: Cornaggia, M|Tibiletti, M G|Albarello, L|Taborelli, M|Dalla Longa, E|Capella, C
PMID: 11218182
Journal: Hum Mol Genet. 2000 Jan 22;9(2):321.
Title: Genomic structure of the human DNA mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC).
Author: Olipitz, W|Sill, H
PMID: 11769276
Journal: Curr Opin Gastroenterol. 2000 Jan;16(1):62-7.
Title: Genomic instability and colorectal cancer.
Author: Grady, W M|Markowitz, S
PMID: 17024019
Journal: Am J Hum Genet. 2001 Jan;68(1):118-127. Epub 2000 Dec 7.
Title: Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds.
Author: Scott, R J|McPhillips, M|Meldrum, C J|Fitzgerald, P E|Adams, K|Spigelman, A D|du Sart, D|Tucker, K|Kirk, J
PMID: 11112663
Journal: J Cell Biochem. 2001;80(3):415-23.
Title: Methylation of CpG loci in 5'-flanking region alters steady-state expression of adenomatous polyposis coli gene in colon cancer cell lines.
Author: Sakamoto, Y|Kitazawa, R|Maeda, S|Kitazawa, S
PMID: 11135372
Journal: Hum Mutat. 2001;17(1):52-60.
Title: Optimization of experimental conditions for RNA-based sequencing of MLH1 and MSH2 genes.
Author: Jakubowska, A|Gorski, B|Kurzawski, G|Debniak, T|Hadaczek, P|Cybulski, C|Kladny, J|Oszurek, O|Scott, R J|Lubinski, J
PMID: 11139242
Journal: J Biochem Biophys Methods. 2001 Jan 30;47(1-2):21-32.
Title: DHPLC mutation analysis of the hereditary nonpolyposis colon cancer (HNPCC) genes hMLH1 and hMSH2.
Author: Holinski-Feder, E|Muller-Koch, Y|Friedl, W|Moeslein, G|Keller, G|Plaschke, J|Ballhausen, W|Gross, M|Baldwin-Jedele, K|Jungck, M|Mangold, E|Vogelsang, H|Schackert, H K|Lohsea, P|Murken, J|Meitinger, T
PMID: 11179758
Journal: Cancer Res. 2001 Feb 1;61(3):896-9.
Title: Microsatellite instability and mismatch-repair protein expression in hereditary and sporadic colorectal carcinogenesis.
Author: Pedroni, M|Sala, E|Scarselli, A|Borghi, F|Menigatti, M|Benatti, P|Percesepe, A|Rossi, G|Foroni, M|Losi, L|Di Gregorio, C|De Pol, A|Nascimbeni, R|Di Betta, E|Salerni, B|de Leon, M P|Roncucci, L
PMID: 11221877
Journal: Cancer Res. 2001 Feb 1;61(3):900-2.
Title: Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer.
Author: Grady, W M|Rajput, A|Lutterbaugh, J D|Markowitz, S D
PMID: 11221878
Journal: Cancer Res. 2001 Feb 15;61(4):1269-71.
Title: Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes.
Author: Frazier, M L|O'Donnell, F T|Kong, S|Gu, X|Campos, I|Luthra, R|Lynch, P M|Amos, C I
PMID: 11245417
Journal: Cancer Res. 2001 Feb 15;61(4):1508-16.
Title: P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin.
Author: Lin, X|Ramamurthi, K|Mishima, M|Kondo, A|Christen, R D|Howell, S B
PMID: 11245458
Journal: Cancer Res. 2001 Feb 15;61(4):1619-23.
Title: MSH6 and MSH3 are rarely involved in genetic predisposition to nonpolypotic colon cancer.
Author: Huang, J|Kuismanen, S A|Liu, T|Chadwick, R B|Johnson, C K|Stevens, M W|Richards, S K|Meek, J E|Gao, X|Wright, F A|Mecklin, J P|Jarvinen, H J|Gronberg, H|Bisgaard, M L|Lindblom, A|Peltomaki, P
PMID: 11245474
Journal: Int J Cancer. 2001 Feb 15;91(4):486-91.
Title: A population based cohort study of patients with multiple colon and endometrial cancer: correlation of microsatellite instability (MSI) status, age at diagnosis and cancer risk.
Author: Cederquist, K|Golovleva, I|Emanuelsson, M|Stenling, R|Gronberg, H
PMID: 11251970
Journal: Hum Mol Genet. 2001 Apr;10(7):735-40.
Title: Deficient DNA mismatch repair: a common etiologic factor for colon cancer.
Author: Peltomaki, P
PMID: 11257106
Journal: Mod Pathol. 2001 Mar;14(3):236-45.
Title: Carcinogenesis in the GI tract: from morphology to genetics and back again.
Author: Redston, M
PMID: 11266532
Journal: Cancer Res. 2001 Mar 15;61(6):2676-83.
Title: Genetic pathways in the evolution of morphologically distinct colorectal neoplasms.
Author: Yashiro, M|Carethers, J M|Laghi, L|Saito, K|Slezak, P|Jaramillo, E|Rubio, C|Koizumi, K|Hirakawa, K|Boland, C R
PMID: 11289147
Journal: Int J Cancer. 2001 May 1;92(3):398-403.
Title: MLH1 and MSH2 protein expression as a pre-screening marker in hereditary and non-hereditary endometrial hyperplasia and cancer.
Author: Berends, M J|Hollema, H|Wu, Y|van Der Sluis, T|Mensink, R G|ten Hoor, K A|Sijmons, R H|de Vries, E G|Pras, E|Mourits, M J|Hofstra, R M|Buys, C H|Kleibeuker, J H|van Der Zee, A G
PMID: 11291077
Journal: Cancer. 2001 Apr 15;91(8):1451-7.
Title: Microsatellite instability and hMLH1/hMSH2 expression in Barrett esophagus-associated adenocarcinoma.
Author: Kulke, M H|Thakore, K S|Thomas, G|Wang, H|Loda, M|Eng, C|Odze, R D
PMID: 11301392
Journal: Lab Invest. 2001 Apr;81(4):535-41.
Title: Microsatellite Instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer.
Author: Salahshor, S|Koelble, K|Rubio, C|Lindblom, A
PMID: 11304573
Journal: Cancer Res. 2001 Apr 1;61(7):2813-5.
Title: Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer.
Author: Schweizer, P|Moisio, A L|Kuismanen, S A|Truninger, K|Vierumaki, R|Salovaara, R|Arola, J|Butzow, R|Jiricny, J|Peltomaki, P|Nystrom-Lahti, M
PMID: 11306449
Journal: Br J Cancer. 2001 Apr 20;84(8):1084-6.
Title: Role of chance in familial aggregation of colorectal cancer.
Author: Katballe, N|Bentzen, S M|Christensen, M|Wikman, F P|Orntoft, T|Laurberg, S
PMID: 11308258
Journal: Eur J Med Res. 2001 Mar 26;6(3):93-100.
Title: Hereditary non-polyposis colorectal cancer (HNPCC): new germline mutation (190-191 del AA) in the human MLH1 gene and review of clinical guidelines for surveillance of affected families.
Author: Schiemann, U|Papatheodorou, L|Glasl, S|Gross, M
PMID: 11309221
Journal: Hum Mutat. 2001 May;17(5):389-96.
Title: Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers.
Author: Lipkin, S M|Wang, V|Stoler, D L|Anderson, G R|Kirsch, I|Hadley, D|Lynch, H T|Collins, F S
PMID: 11317354
Journal: J Cell Physiol. 2001 Jun;187(3):356-64.
Title: Growth inhibition due to complementation of transforming growth factor-beta receptor type II-defect by human chromosome 3 transfer in human colorectal carcinoma cells.
Author: Miyafuji, Y|Zhong, X|Uchida, I|Koi, M|Hemmi, H
PMID: 11319759
Journal: Cancer Lett. 2001 Jun 10;167(1):91-7.
Title: Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features.
Author: Shannon, B A|Iacopetta, B J
PMID: 11323103
Journal: Cancer Res. 2001 May 1;61(9):3573-7.
Title: Accelerated age-related CpG island methylation in ulcerative colitis.
Author: Issa, J P|Ahuja, N|Toyota, M|Bronner, M P|Brentnall, T A
PMID: 11325821
Journal: Nat Biotechnol. 2001 May;19(5):434-9.
Title: A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition.
Author: Noensie, E N|Dietz, H C
PMID: 11329012
Journal: J Biol Chem. 2001 Jul 13;276(28):25813-22.
Title: The p53-regulated cyclin-dependent kinase inhibitor, p21 (cip1, waf1, sdi1), is not required for global genomic and transcription-coupled nucleotide excision repair of UV-induced DNA photoproducts.
Author: Adimoolam, S|Lin, C X|Ford, J M
PMID: 11331289
Journal: J Med Genet. 2001 May;38(5):318-22.
Title: Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree.
Author: Wagner, A|Hendriks, Y|Meijers-Heijboer, E J|de Leeuw, W J|Morreau, H|Hofstra, R|Tops, C|Bik, E|Brocker-Vriends, A H|van Der Meer, C|Lindhout, D|Vasen, H F|Breuning, M H|Cornelisse, C J|van Krimpen, C|Niermeijer, M F|Zwinderman, A H|Wijnen, J|Fodde, R
PMID: 11333868
Journal: Scand J Gastroenterol. 2001 Apr;36(4):405-9.
Title: Allelic loss of chromosome 2p21-16.3 is associated with reduced survival in sporadic colorectal cancer.
Author: Bisgaard, M L|Jager, A C|Dalgaard, P|Sondergaard, J O|Rehfeld, J F|Nielsen, F C
PMID: 11336166
Journal: Clin Chem Lab Med. 2001 Feb;39(2):121-8.
Title: Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer.
Author: Maekawa, M|Sugano, K|Ushiama, M|Fukayama, N|Nomoto, K|Kashiwabara, H|Fujita, S|Kakizoe, T
PMID: 11341745
Journal: J Pediatr. 2001 May;138(5):629-35.
Title: Germline characterization of early-aged onset of hereditary non-polyposis colorectal cancer.
Author: Huang, S C|Lavine, J E|Boland, P S|Newbury, R O|Kolodner, R|Pham, T T|Arnold, C N|Boland, C R|Carethers, J M
PMID: 11343035
Journal: Ned Tijdschr Geneeskd. 2001 Apr 21;145(16):780-2.
Title: [From gene to disease; from DNA 'mismatch' repair genes to hereditary non-polyposis colorectal carcinoma].
Author: Wijnen, J T|Morreau, H|Vasen, H F
PMID: 11346916
Journal: Gut. 2001 Jun;48(6):821-9.
Title: Microsatellite instability and the clinicopathological features of sporadic colorectal cancer.
Author: Ward, R|Meagher, A|Tomlinson, I|O'Connor, T|Norrie, M|Wu, R|Hawkins, N
PMID: 11358903
Journal: J Clin Pathol. 2001 Jun;54(6):484-7.
Title: Immunohistochemistry for MSH2 and MHL1: a method for identifying mismatch repair deficient colorectal cancer.
Author: Stone, J G|Robertson, D|Houlston, R S
PMID: 11376026
Journal: Cancer Genet Cytogenet. 2001 Apr 15;126(2):85-96.
Title: Causes of microsatellite instability in colorectal tumors: implications for hereditary non-polyposis colorectal cancer screening.
Author: Potocnik, U|Glavac, D|Golouh, R|Ravnik-Glavac, M
PMID: 11376800
Journal: Hum Mutat. 2001 Jun;17(6):521.
Title: Four novel MSH2 and MLH1 frameshift mutations and occurrence of a breast cancer phenocopy in hereditary nonpolyposis colorectal cancer.
Author: Caluseriu, O|Cordisco, E L|Viel, A|Majore, S|Nascimbeni, R|Pucciarelli, S|Genuardi, M
PMID: 11385712
Journal: Cancer Res. 2001 Jun 1;61(11):4545-9.
Title: Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC).
Author: Loukola, A|Eklin, K|Laiho, P|Salovaara, R|Kristo, P|Jarvinen, H|Mecklin, J P|Launonen, V|Aaltonen, L A
PMID: 11389088
Journal: Swiss Surg. 2001;7(3):99-104.
Title: [Multidisciplinary management of hereditary colorectal cancer].
Author: Soravia, C|Delozier-Blanchet, C|Blouin, J L|Brundler, M A|Egger, J F|Queneau, P E|Roth, A D|Marti, M C|Antonarakis, S E|Morel, P|Hutter, P
PMID: 11407044
Journal: Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7164-9.
Title: Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide.
Author: Marra, G|D'Atri, S|Corti, C|Bonmassar, L|Cattaruzza, M S|Schweizer, P|Heinimann, K|Bartosova, Z|Nystrom-Lahti, M|Jiricny, J
PMID: 11416201
Journal: Oncogene. 2001 May 24;20(23):2976-81.
Title: A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population.
Author: Chan, T L|Yuen, S T|Ho, J W|Chan, A S|Kwan, K|Chung, L P|Lam, P W|Tse, C W|Leung, S Y
PMID: 11420710
Journal: Mutat Res. 2001 Jul 12;486(2):155-64.
Title: Heterocyclic amine induced apoptotic response in the human lymphoblastoid cell line TK6 is linked to mismatch repair status.
Author: Duc, R|Leong-Morgenthaler, P M
PMID: 11425520
Journal: Cancer Res. 2001 Jul 1;61(13):5193-201.
Title: Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
Author: Meyers, M|Wagner, M W|Hwang, H S|Kinsella, T J|Boothman, D A
PMID: 11431359
Journal: Genes Chromosomes Cancer. 2001 Aug;31(4):357-61.
Title: Methylation pattern of different regions of the MLH1 promoter and silencing of gene expression in hereditary and sporadic colorectal cancer.
Author: Menigatti, M|Di Gregorio, C|Borghi, F|Sala, E|Scarselli, A|Pedroni, M|Foroni, M|Benatti, P|Roncucci, L|Ponz de Leon, M|Percesepe, A
PMID: 11433526
Journal: Cancer Epidemiol Biomarkers Prev. 2001 Jul;10(7):793-8.
Title: Second primary cancers after sporadic and familial colorectal cancer.
Author: Hemminki, K|Li, X|Dong, C
PMID: 11440965
Journal: G Chir. 2001 May;22(5):165-8.
Title: [Genetics-based prognosis evaluation of patients surgically treated for sporadic colorectal cancer].
Author: Midiri, G|Consorti, F|Giarnieri, E|Soda, G|Bosco, D|Lorenzotti, A|Luzzatto, L|Conte, S|Lo Russo, M|Vecchione, A|Beltrami, V
PMID: 11443839
Journal: Int J Radiat Biol. 2001 Jul;77(7):773-80.
Title: Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells.
Author: Franchitto, A|Pichierri, P|Genuardi, M|De Santis, A|Palitti, F
PMID: 11454277
Journal: Gene. 2001 Jul 11;272(1-2):301-13.
Title: Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype.
Author: Ohmiya, N|Matsumoto, S|Yamamoto, H|Baranovskaya, S|Malkhosyan, S R|Perucho, M
PMID: 11470537
Journal: Int J Oncol. 2001 Sep;19(3):567-70.
Title: hMLH1 and hMSH2 expression in human hepatocellular carcinoma.
Author: Wang, L|Bani-Hani, A|Montoya, D P|Roche, P C|Thibodeau, S N|Burgart, L J|Roberts, L R
PMID: 11494037
Journal: Int J Cancer. 2001 Sep 20;95(5):323-8.
Title: Clinical and biologic heterogeneity of hereditary nonpolyposis colorectal cancer.
Author: Benatti, P|Roncucci, L|Ganazzi, D|Percesepe, A|Di Gregorio, C|Pedroni, M|Borghi, F|Sala, E|Scarselli, A|Menigatti, M|Rossi, G|Genuardi, M|Viel, A|Ponz De Leon, M
PMID: 11494233
Journal: Mutat Res. 2001 Sep 1;480-481:85-95.
Title: Reduction of spontaneous mutagenesis in mismatch repair-deficient and proficient cells by dietary antioxidants.
Author: Mure, K|Rossman, T G
PMID: 11506802
Journal: Cancer Res. 2001 Aug 15;61(16):6042-5.
Title: CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer.
Author: Bala, S|Peltomaki, P
PMID: 11507050
Journal: Cancer Res. 2001 Sep 1;61(17):6555-62.
Title: The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.
Author: Jacob, S|Aguado, M|Fallik, D|Praz, F
PMID: 11522654
Journal: Am J Hum Genet. 2001 Oct;69(4):780-90.
Title: The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.
Author: Cunningham, J M|Kim, C Y|Christensen, E R|Tester, D J|Parc, Y|Burgart, L J|Halling, K C|McDonnell, S K|Schaid, D J|Walsh Vockley, C|Kubly, V|Nelson, H|Michels, V V|Thibodeau, S N
PMID: 11524701
Journal: Histopathology. 2001 Sep;39(3):250-8.
Title: MLH1 and MSH2 protein immunohistochemistry is useful for detection of hereditary non-polyposis colorectal cancer in young patients.
Author: Paraf, F|Gilquin, M|Longy, M|Gilbert, B|Gorry, P|Petit, B|Labrousse, F
PMID: 11532035
Journal: J Natl Cancer Inst. 2001 Sep 5;93(17):1307-13.
Title: Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas.
Author: Hawkins, N J|Ward, R L
PMID: 11535705
Journal: Am J Pathol. 2001 Sep;159(3):1129-35.
Title: CpG island methylation in colorectal adenomas.
Author: Rashid, A|Shen, L|Morris, J S|Issa, J P|Hamilton, S R
PMID: 11549606
Journal: Hum Mol Genet. 2001 Sep 1;10(18):1889-900.
Title: Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae.
Author: Ellison, A R|Lofing, J|Bitter, G A
PMID: 11555625
Journal: Genet Res. 2001 Aug;78(1):49-57.
Title: Simulating genealogies of selected alleles in a population of variable size.
Author: Slatkin, M
PMID: 11556137
Journal: Virchows Arch. 2001 Aug;439(2):191-5.
Title: Genotype and phenotype of a new 2-bp deletion of hMSH2 at codon 233.
Author: Muller, A|Beyser, K|Arps, H|Bolander, S|Becker, H|Ruschhoff, J
PMID: 11561760
Journal: J Cancer Res Clin Oncol. 2001 Sep;127(9):565-9.
Title: Comparison of Alu-PCR, microsatelite instability, and immunohistochemical analyses in finding features characteristic for hereditary nonpolyposis colorectal cancer.
Author: Debniak, T|Gorski, B|Cybulski, C|Jakubowska, A|Kurzawski, G|Kladny, J|Lubinski, J
PMID: 11570578
Journal: J Clin Oncol. 2001 Oct 1;19(19):3944-50.
Title: Molecular screening for hereditary nonpolyposis colorectal cancer: a prospective, population-based study.
Author: Percesepe, A|Borghi, F|Menigatti, M|Losi, L|Foroni, M|Di Gregorio, C|Rossi, G|Pedroni, M|Sala, E|Vaccina, F|Roncucci, L|Benatti, P|Viel, A|Genuardi, M|Marra, G|Kristo, P|Peltomaki, P|Ponz de Leon, M
PMID: 11579115
Journal: Dis Colon Rectum. 2001 Sep;44(9):1281-9.
Title: Evaluation of Bethesda guidelines in relation to microsatellite instability.
Author: Wullenweber, H P|Sutter, C|Autschbach, F|Willeke, F|Kienle, P|Benner, A|Bahring, J|Kadmon, M|Herfarth, C|von Knebel Doeberitz, M|Gebert, J
PMID: 11584201
Journal: Cancer Res. 2001 Oct 1;61(19):6991-5.
Title: Age-related hypermethylation of the 5' region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development.
Author: Nakagawa, H|Nuovo, G J|Zervos, E E|Martin, E W Jr|Salovaara, R|Aaltonen, L A|de la Chapelle, A
PMID: 11585722
Journal: J Pathol. 2001 Sep;195(2):171-8.
Title: Mechanisms of oncogenesis in colon versus rectal cancer.
Author: Kapiteijn, E|Liefers, G J|Los, L C|Kranenbarg, E K|Hermans, J|Tollenaar, R A|Moriya, Y|van de Velde, C J|van Krieken, J H
PMID: 11592095
Journal: Br J Cancer. 2001 Sep 28;85(7):1037-46.
Title: Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients.
Author: Soliman, A S|Bondy, M L|El-Badawy, S A|Mokhtar, N|Eissa, S|Bayoumy, S|Seifeldin, I A|Houlihan, P S|Lukish, J R|Watanabe, T|Chan, A O|Zhu, D|Amos, C I|Levin, B|Hamilton, S R
PMID: 11592777
Journal: Dis Colon Rectum. 2001 Oct;44(10):1503-8.
Title: Loss of heterozygosity and HIV infection in patients with anal squamous-cell carcinoma.
Author: Gervaz, P|Efron, J|Poza, A A|Chun, S W|Pham, T T|Woodhouse, S|Wexner, S D|Carethers, J M
PMID: 11598481
Journal: J Clin Oncol. 2001 Oct 15;19(20):4074-80.
Title: MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families.
Author: Vasen, H F|Stormorken, A|Menko, F H|Nagengast, F M|Kleibeuker, J H|Griffioen, G|Taal, B G|Moller, P|Wijnen, J T
PMID: 11600610
Journal: Onkologie. 2001 Sep;24 Suppl 5:4-8.
Title: [Hereditary colorectal carcinomas - reflection on preventive surgery].
Author: Pistorius, S|Schackert, H K|Saeger, H D
PMID: 11600806
Journal: Ann Intern Med. 2001 Oct 16;135(8 Pt 1):566-76.
Title: Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer.
Author: Raedle, J|Trojan, J|Brieger, A|Weber, N|Schafer, D|Plotz, G|Staib-Sebler, E|Kriener, S|Lorenz, M|Zeuzem, S
PMID: 11601928
Journal: Int J Oncol. 2001 Nov;19(5):891-5.
Title: MSH2 and MLH1 immunodetection and the prognosis of colon cancer.
Author: Perrin, J|Gouvernet, J|Parriaux, D|Noguchi, T|Giovannini, M H|Giovannini, M|Delpero, J R|Birnbaum, D|Monges, G
PMID: 11604984
Journal: Cancer Res. 2001 Oct 15;61(20):7616-22.
Title: Nontruncating APC germ-line mutations and mismatch repair deficiency play a minor role in APC mutation-negative polyposis.
Author: Heinimann, K|Thompson, A|Locher, A|Furlanetto, T|Bader, E|Wolf, A|Meier, R|Walter, K|Bauerfeind, P|Marra, G|Muller, H|Foernzler, D|Dobbie, Z
PMID: 11606402
Journal: Gastroenterology. 2001 Oct;121(4):830-8.
Title: The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer.
Author: Samowitz, W S|Curtin, K|Lin, H H|Robertson, M A|Schaffer, D|Nichols, M|Gruenthal, K|Leppert, M F|Slattery, M L
PMID: 11606497
Journal: Cancer Res. 2001 Nov 1;61(21):7798-802.
Title: The role of hPMS1 and hPMS2 in predisposing to colorectal cancer.
Author: Liu, T|Yan, H|Kuismanen, S|Percesepe, A|Bisgaard, M L|Pedroni, M|Benatti, P|Kinzler, K W|Vogelstein, B|Ponz de Leon, M|Peltomaki, P|Lindblom, A
PMID: 11691795
Journal: Oncogene. 2001 Oct 25;20(48):7120-7.
Title: Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression.
Author: Deng, G|Chen, A|Pong, E|Kim, Y S
PMID: 11704838
Journal: Cancer Res. 2001 Nov 15;61(22):8290-7.
Title: Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.
Author: Yan, T|Schupp, J E|Hwang, H S|Wagner, M W|Berry, S E|Strickfaden, S|Veigl, M L|Sedwick, W D|Boothman, D A|Kinsella, T J
PMID: 11719462
Journal: Br J Cancer. 2001 Nov 16;85(10):1486-91.
Title: Minisatellite instability is found in colorectal tumours with mismatch repair deficiency.
Author: Coleman, M G|Gough, A C|Bunyan, D J|Braham, D|Eccles, D M|Primrose, J N
PMID: 11720433
Journal: Eur J Med Res. 2001 Nov 20;6(11):473-82.
Title: Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms?
Author: Muller-Koch, Y|Kopp, R|Lohse, P|Baretton, G|Stoetzer, A|Aust, D|Daum, J|Kerker, B|Gross, M|Dietmeier, W|Holinski-Feder, E
PMID: 11726306
Journal: Gastroenterology. 2001 Dec;121(6):1300-9.
Title: Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability.
Author: Miyakura, Y|Sugano, K|Konishi, F|Ichikawa, A|Maekawa, M|Shitoh, K|Igarashi, S|Kotake, K|Koyama, Y|Nagai, H
PMID: 11729109
Journal: Nihon Shokakibyo Gakkai Zasshi. 2001 Nov;98(11):1263-71.
Title: [Alternations of p53 gene, microsatellite instability and proliferation associated antigen Ki-67 in the synchronous multiple colorectal cancers].
Author: Asakawa, H|Koido, S|Torii, A|Ikegami, M
PMID: 11729653
Journal: Am J Pathol. 2001 Dec;159(6):2107-16.
Title: Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.
Author: Young, J|Simms, L A|Biden, K G|Wynter, C|Whitehall, V|Karamatic, R|George, J|Goldblatt, J|Walpole, I|Robin, S A|Borten, M M|Stitz, R|Searle, J|McKeone, D|Fraser, L|Purdie, D R|Podger, K|Price, R|Buttenshaw, R|Walsh, M D|Barker, M|Leggett, B A|Jass, J R
PMID: 11733361
Journal: Hum Mol Genet. 2001 Dec 15;10(26):3001-7.
Title: DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Author: Esteller, M|Fraga, M F|Guo, M|Garcia-Foncillas, J|Hedenfalk, I|Godwin, A K|Trojan, J|Vaurs-Barriere, C|Bignon, Y J|Ramus, S|Benitez, J|Caldes, T|Akiyama, Y|Yuasa, Y|Launonen, V|Canal, M J|Rodriguez, R|Capella, G|Peinado, M A|Borg, A|Aaltonen, L A|Ponder,
PMID: 11751682
Journal: Pol J Pathol. 2001;52(3):125-32.
Title: Fhit protein expression in hereditary and sporadic colorectal cancers.
Author: Hadaczek, P|Debniak, T|Kurzawski, G|Jakubowska, A|Huzarski, T|Huebner, K|Lubinski, J
PMID: 11769399
Journal: Zhonghua Yi Xue Za Zhi. 2001 Feb 10;81(3):158-61.
Title: [Analysis of the methylation in CpG island by denaturing high-performance liquid chromatography].
Author: Deng, D|Deng, G|Lu, Y
PMID: 11798868
Journal: Hepatogastroenterology. 2001 Nov-Dec;48(42):1635-40.
Title: Current trends in screening and secondary prevention of colorectal cancer.
Author: Crespi, M|Stigliano, V|Assisi, D
PMID: 11813590
Journal: Kongressbd Dtsch Ges Chir Kongr. 2001;118:213-7.
Title: [Preventive therapy of HNPCC--a study concept].
Author: Moslein, G|Albrecht, J|Ohmann, C|Schackert, H K
PMID: 11824249
Journal: Kongressbd Dtsch Ges Chir Kongr. 2001;118:95-100.
Title: [Progress in oncological visceral surgery: colon carcinoma].
Author: Herfarth, C|Weitz, J
PMID: 11824372
Journal: Gastroenterol Clin Biol. 2001 Oct;25(10):929-31.
Title: [Search for microsatellite instability in colorectal cancer: an effective way to detect HNPCC?].
Author: Terdiman, J|Gum Jr, J|Conrad, P|Miller, G|Weinberg, V|Crawley, S|Levin, T|Reeves, C|Schmitt, A|Hepburn, M|Sleisenger, M|Kim, Y
PMID: 11852407
Journal: Verh Dtsch Ges Pathol. 2001;85:208-11.
Title: [Esophageal, gastric and colorectal tumors].
Author: Stolte, M
PMID: 11894400
Journal: Cancer Detect Prev. 2001;25(6):503-10.
Title: hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer.
Author: Kim, J C|Kim, H C|Roh, S A|Koo, K H|Lee, D H|Yu, C S|Lee, J H|Kim, T W|Lee, H L|Beck, N E|Bodmer, W F
PMID: 12132870
Journal: J Appl Genet. 2001;42(3):359-66.
Title: Age at diagnosis of cancer as predictor of mutation occurrence in families suspected of HNPCC.
Author: Kurzawski, G|Debniak, T|Kladny, J|Lubinski, J
PMID: 14564042
Journal: Fam Cancer. 2001;1(2):87-92.
Title: The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study.
Author: Muller, W|Burgart, L J|Krause-Paulus, R|Thibodeau, S N|Almeida, M|Edmonston, T B|Boland, C R|Sutter, C|Jass, J R|Lindblom, A|Lubinski, J|MacDermot, K|Sanders, D S|Morreau, H|Muller, A|Oliani, C|Orntoft, T|Ponz De Leon, M|Rosty, C|Rodriguez-Bigas, M|Ruscho
PMID: 14574003
Journal: Fam Cancer. 2001;1(2):93-9.
Title: Mutations of the 'minor' mismatch repair gene MSH6 in typical and atypical hereditary nonpolyposis colorectal cancer.
Author: Lucci-Cordisco, E|Rovella, V|Carrara, S|Percesepe, A|Pedroni, M|Bellacosa, A|Caluseriu, O|Forasarig, M|Anti, M|Neri, G|Ponz de Leon, M|Viel, A|Genuardi, M
PMID: 14574004
Journal: Fam Cancer. 2001;1(2):101-5.
Title: Cafe-au-lait spots and early onset colorectal neoplasia: a variant of HNPCC?
Author: Trimbath, J D|Petersen, G M|Erdman, S H|Ferre, M|Luce, M C|Giardiello, F M
PMID: 14574005
Journal: Fam Cancer. 2001;1(2):107-9.
Title: Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation?
Author: Marcelis, C L|van der Putten, H W|Tops, C|Lutgens, L C|Moog, U
PMID: 14574006
Journal: Fam Cancer. 2001;1(1):9-15.
Title: Genotype and phenotype in hereditary nonpolyposis colon cancer: a study of families with different vs. shared predisposing mutations.
Author: Peltomaki, P|Gao, X|Mecklin, J P
PMID: 14574010
Journal: Fam Cancer. 2001;1(3-4):169-73.
Title: Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry.
Author: Stormorken, A T|Muller, W|Lemkemeyer, B|Apold, J|Wijnen, J T|Fodde, R|Moslein, G|Moller, P
PMID: 14574174
Journal: Methods Mol Med. 2001;50:81-6.
Title: Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer.
Author: Halling, K C|Roche, P C
PMID: 21318818
Journal: Methods Mol Med. 2001;39:383-8.
Title: Immunostaining human paraffin-embedded sections for mismatch repair proteins.
Author: Mackean, M|Brown, R
PMID: 21340794
Journal: Am J Hum Genet. 2002 Jan;70(1):26-37.
Title: Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant.
Author: Berends, Maran J W|Wu, Ying|Sijmons, Rolf H|Mensink, Rob G J|van der Sluis, Tineke|Hordijk-Hos, Jannet M|de Vries, Elisabeth G E|Hollema, Harry|Karrenbeld, Arend|Buys, Charles H C M|van der Zee, Ate G J|Hofstra, Robert M W|Kleibeuker, Jan H
PMID: 11709755
Journal: Hum Mutat. 2002 Jan;19(1):82.
Title: Seven novel MLH1 and MSH2 germline mutations in hereditary nonpolyposis colorectal cancer.
Author: Kruger, Stefan|Plaschke, Jens|Pistorius, Steffen|Jeske, Birgit|Haas, Stephan|Kramer, Heike|Hinterseher, Irene|Bier, Andrea|Kreuz, Friedmar R|Theissig, Franz|Saeger, Hans D|Schackert, Hans K
PMID: 11754112
Journal: Gut. 2002 Jan;50(1):43-51.
Title: Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients.
Author: Katballe, N|Christensen, M|Wikman, F P|Orntoft, T F|Laurberg, S
PMID: 11772966
Journal: Int J Cancer. 2002 Jan 10;97(2):205-10.
Title: Proficient mismatch repair protein expression in Hodgkin and Reed Sternberg cells.
Author: Re, Daniel|Benenson, Lena|Wickenhauser, Claudia|Starostik, Petr|Staratschek-Jox, Andrea|Muller-Hermelink, Hans Konrad|Diehl, Volker|Wolf, Jurgen
PMID: 11774265
Journal: Gut. 2002 Feb;50(2):218-23.
Title: An insight into the genetic pathway of adenocarcinoma of the small intestine.
Author: Wheeler, J M D|Warren, B F|Mortensen, N J McC|Kim, H C|Biddolph, S C|Elia, G|Beck, N E|Williams, G T|Shepherd, N A|Bateman, A C|Bodmer, W F
PMID: 11788563
Journal: Int J Cancer. 2002 Feb 10;97(5):643-8.
Title: Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation.
Author: Plaschke, Jens|Kruger, Stefan|Pistorius, Steffen|Theissig, Franz|Saeger, Hans D|Schackert, Hans K
PMID: 11807791
Journal: Cancer Res. 2002 Jan 15;62(2):359-62.
Title: A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple cafe-au-lait spots.
Author: Whiteside, Darcy|McLeod, Ross|Graham, Gail|Steckley, Jamie L|Booth, Karen|Somerville, Martin J|Andrew, Susan E
PMID: 11809679
Journal: Gut. 2002 Mar;50(3):382-6.
Title: Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation.
Author: Rijcken, F E M|Hollema, H|Kleibeuker, J H
PMID: 11839719
Journal: Gut. 2002 Mar;50(3):405-12.
Title: Pathogenicity of missense and splice site mutations in hMSH2 and hMLH1 mismatch repair genes: implications for genetic testing.
Author: Cravo, M|Afonso, A J|Lage, P|Albuquerque, C|Maia, L|Lacerda, C|Fidalgo, P|Chaves, P|Cruz, C|Nobre-Leitao, C
PMID: 11839723
Journal: J Clin Oncol. 2002 Feb 15;20(4):1043-8.
Title: Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors.
Author: Lindor, Noralane M|Burgart, Lawrence J|Leontovich, Olga|Goldberg, Richard M|Cunningham, Julie M|Sargent, Daniel J|Walsh-Vockley, Catherine|Petersen, Gloria M|Walsh, Michael D|Leggett, Barbara A|Young, Joanne P|Barker, Melissa A|Jass, Jeremy R|Hopper, John
PMID: 11844828
Journal: J Invest Dermatol. 2002 Jan;118(1):79-86.
Title: High-frequency microsatellite instability is associated with defective DNA mismatch repair in human melanoma.
Author: Alvino, Ester|Marra, Giancarlo|Pagani, Elena|Falcinelli, Sabrina|Pepponi, Rita|Perrera, Claudia|Haider, Ritva|Castiglia, Daniele|Ferranti, Giulio|Bonmassar, Enzo|Jiricny, Josef|Zambruno, Giovanna|D'Atri, Stefania
PMID: 11851879
Journal: Cancer Invest. 2002;20(1):102-9.
Title: Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC).
Author: Muller, Annegret|Fishel, Richard
PMID: 11852992
Journal: Hum Mol Genet. 2002 Feb 15;11(4):445-50.
Title: Distinct PTEN mutational spectra in hereditary non-polyposis colon cancer syndrome-related endometrial carcinomas compared to sporadic microsatellite unstable tumors.
Author: Zhou, Xiao-Ping|Kuismanen, Shannon|Nystrom-Lahti, Minna|Peltomaki, Paivi|Eng, Charis
PMID: 11854177
Journal: Oncogene. 2002 Feb 21;21(9):1443-9.
Title: Chromosomal autonomy of hMLH1 methylation in colon cancer.
Author: Li, Hui|Myeroff, Lois|Kasturi, Lakshmi|Krumroy, Lisa|Schwartz, Stuart|Willson, James K V|Stanbridge, Eric|Casey, Graham|Markowitz, Sanford
PMID: 11857087
Journal: Int J Cancer. 2002 Feb 20;97(6):823-7.
Title: Associations between family history of colorectal cancer and genetic alterations in tumors.
Author: Slattery, Martha L|Curtin, Karen|Schaffer, Donna|Anderson, Kristen|Samowitz, Wade
PMID: 11857362
Journal: Cancer Res. 2002 Feb 15;62(4):1014-9.
Title: Exclusion of breast cancer as an integral tumor of hereditary nonpolyposis colorectal cancer.
Author: Muller, Annegret|Edmonston, Tina Bocker|Corao, Diana A|Rose, Deborah G|Palazzo, Juan P|Becker, Heinz|Fry, Robert D|Rueschoff, Josef|Fishel, Richard
PMID: 11861375
Journal: Br J Cancer. 2002 Feb 12;86(4):574-9.
Title: Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer.
Author: Deng, G|Peng, E|Gum, J|Terdiman, J|Sleisenger, M|Kim, Y S
PMID: 11870540
Journal: J Biochem Biophys Methods. 2002 Mar 4;51(1):89-100.
Title: Mutation analysis of MLH1 and MSH2 genes performed by denaturing high-performance liquid chromatography.
Author: Kurzawski, Grzegorz|Safranow, Krzysztof|Suchy, Janina|Chlubek, Dariusz|Scott, Rodney J|Lubinski, Jan
PMID: 11879922
Journal: Oncogene. 2002 Mar 14;21(12):1928-33.
Title: Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.
Author: Porter, Timothy R|Richards, Frances M|Houlston, Richard S|Evans, D Gareth R|Jankowski, Janusz A|Macdonald, Fiona|Norbury, Gail|Payne, Stewart J|Fisher, Samantha A|Tomlinson, Ian|Maher, Eamonn R
PMID: 11896626
Journal: Biochimie. 2002 Jan;84(1):27-47.
Title: DNA mismatch repair defects: role in colorectal carcinogenesis.
Author: Jacob, Sandrine|Praz, Francoise
PMID: 11900875
Journal: Lancet Oncol. 2002 Feb;3(2):83-8.
Title: Emerging pathways in colorectal-cancer development.
Author: Haydon, Andrew M M|Jass, Jeremy R
PMID: 11905459
Journal: Gastroenterology. 2002 Apr;122(4):940-7.
Title: Hereditary nonpolyposis colorectal cancer in young colorectal cancer patients: high-risk clinic versus population-based registry.
Author: Terdiman, Jonathan P|Levin, Theodore R|Allen, Brian A|Gum, James R Jr|Fishbach, Andrea|Conrad, Peggy G|Miller, Glenn A|Weinberg, Vivian|Bachman, Ronald|Bergoffen, Joann|Stembridge, Ann|Toribara, Neil W|Sleisenger, Marvin H|Kim, Young S
PMID: 11910346
Journal: Clin Exp Metastasis. 2002;19(1):71-7.
Title: Is reduced expression of mismatch repair genes MLH1 and MSH2 in patients with sporadic colorectal cancer related to their prognosis?
Author: Kruschewski, Martin|Noske, Aurelia|Haier, Jorg|Runkel, Norbert|Anagnostopoulos, Yanis|Buhr, Heinz Johannes
PMID: 11918085
Journal: Cancer. 2002 Feb 15;94(4):911-20.
Title: Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma.
Author: Furukawa, Taiji|Konishi, Fumio|Shitoh, Kazuhisa|Kojima, Masayuki|Nagai, Hideo|Tsukamoto, Toshihiko
PMID: 11920458
Journal: Int J Cancer. 2002 Apr 10;98(5):774-9.
Title: Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain.
Author: Caldes, Trinidad|Godino, Javier|de la Hoya, Miguel|Garcia Carbonero, Iciar|Perez Segura, Pedro|Eng, Charis|Benito, Manuel|Diaz-Rubio, Eduardo
PMID: 11920650
Journal: World J Gastroenterol. 2002 Apr;8(2):263-6.
Title: Report of 16 kindreds and one kindred with hMLH1 germline mutation.
Author: Zhao, Bo|Wang, Zhen-Jun|Xu, Yu-Feng|Wan, Yuan-Lian|Li, Peng|Huang, Yan-Ting
PMID: 11925604
Journal: Jpn J Clin Oncol. 2002 Jan;32(1):3-8.
Title: Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
Author: Nomoto, Kiyoaki|Maekawa, Masato|Sugano, Kokichi|Ushiama, Mineko|Fukayama, Noriko|Fujita, Shin|Kakizoe, Tadao
PMID: 11932355
Journal: J Cancer Res Clin Oncol. 2002 Mar;128(3):119-24.
Title: Comprehensive analysis of promoter methylation and altered expression of hMLH1 in gastric cancer cell lines with microsatellite instability.
Author: Kang, Y-H|Bae, S I|Kim, W H
PMID: 11935297
Journal: Int J Cancer. 2002 Apr 20;98(6):844-50.
Title: Evidence for an age-related influence of microsatellite instability on colorectal cancer survival.
Author: Farrington, Susan M|McKinley, Aileen J|Carothers, Andrew D|Cunningham, Christopher|Bubb, Vivien J|Sharp, Linda|Wyllie, Andrew H|Dunlop, Malcolm G
PMID: 11948461
Journal: J Surg Oncol. 2002 May;80(1):34-40.
Title: Microsatellite analysis of fecal DNA for colorectal cancer detection.
Author: Koshiji, Minori|Yonekura, Yasuhiro|Saito, Takamichi|Yoshioka, Kazuhiko
PMID: 11967905
Journal: Swiss Med Wkly. 2002 Feb 9;132(5-6):57-63.
Title: Expression of the hMSH6 mismatch-repair protein in colon cancer and HeLa cells.
Author: Klingler, H|Hemmerle, C|Bannwart, F|Haider, R|Cattaruzza, M S|Marra, G
PMID: 11971198
Journal: Oncogene. 2002 Apr 25;21(18):2873-9.
Title: Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level.
Author: Claij, Nanna|Te Riele, Hein
PMID: 11973647
Journal: Gan To Kagaku Ryoho. 2002 Apr;29(4):539-44.
Title: [Hereditary non-polyposis colorectal cancer (HNPCC)].
Author: Takenoshita, Seiichi|Takita, Kenichi
PMID: 11977537
Journal: Eur J Cancer. 2002 May;38(7):858-66.
Title: Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.
Author: Jass, J R|Walsh, M D|Barker, M|Simms, L A|Young, J|Leggett, B A
PMID: 11978509
Journal: Gastroenterology. 2002 May;122(5):1376-87.
Title: CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.
Author: Hawkins, Nicholas|Norrie, Mark|Cheong, Kay|Mokany, Elisa|Ku, Su-Lyn|Meagher, Alan|O'Connor, Terence|Ward, Robyn
PMID: 11984524
Journal: Cancer Genet Cytogenet. 2002 Apr 1;134(1):46-54.
Title: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
Author: Planck, Maria|Halvarsson, Britta|Palsson, Eva|Hallen, Magnus|Ekelund, Mats|Palsson, Birger|Baldetorp, Bo|Nilbert, Mef
PMID: 11996796
Journal: Am J Pathol. 2002 May;160(5):1823-30.
Title: CpG island methylation in aberrant crypt foci of the colorectum.
Author: Chan, Annie On-On|Broaddus, Russell R|Houlihan, Patrick S|Issa, Jean-Pierre J|Hamilton, Stanley R|Rashid, Asif
PMID: 12000733
Journal: Dis Colon Rectum. 2002 May;45(5):674-80.
Title: The role of hMLH1 methylation in the development of synchronous sporadic colorectal carcinomas.
Author: Norrie, Mark W A|Hawkins, Nicholas J|Todd, Alison V|Meagher, Alan P|O'Connor, Terence W|Ward, Robyn L
PMID: 12004219
Journal: Cancer. 2002 May 1;94(9):2502-10.
Title: High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum.
Author: Planck, Maria|Rambech, Eva|Moslein, Gabriela|Muller, Wolfram|Olsson, Hakan|Nilbert, Mef
PMID: 12015776
Journal: Hum Mol Genet. 2002 May 15;11(11):1303-10.
Title: Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome.
Author: Kariola, Reetta|Raevaara, Tiina E|Lonnqvist, Karin E|Nystrom-Lahti, Minna
PMID: 12019211
Journal: Biochem J. 2002 Jun 1;364(Pt 2):441-7.
Title: Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
Author: Catani, M Valeria|Costanzo, Antonio|Savini, Isabella|Levrero, Massimo|de Laurenzi, Vincenzo|Wang, Jean Y J|Melino, Gerry|Avigliano, Luciana
PMID: 12023887
Journal: Cancer Res. 2002 Jun 1;62(11):3070-6.
Title: Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Author: Liu, Lili|Schwartz, Stuart|Davis, Brian M|Gerson, Stanton L
PMID: 12036916
Journal: Mutat Res. 2002 Jun 19;503(1-2):37-42.
Title: A hMLH1 genomic mutation and associated novel mRNA defects in a hereditary non-polyposis colorectal cancer family.
Author: Tanko, Q|Franklin, B|Lynch, H|Knezetic, J
PMID: 12052501
Journal: Am J Pathol. 2002 Jun;160(6):1953-8.
Title: Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
Author: Kuismanen, Shannon A|Moisio, Anu-Liisa|Schweizer, Pascal|Truninger, Kaspar|Salovaara, Reijo|Arola, Johanna|Butzow, Ralf|Jiricny, Josef|Nystrom-Lahti, Minna|Peltomaki, Paivi
PMID: 12057899
Journal: Hepatogastroenterology. 2002 May-Jun;49(45):672-7.
Title: RER and LOH association with sporadic colorectal cancer in Taiwanese patients.
Author: Tsai, Ming-Hong|Yang, Ya-Chien|Chen, Kuang-Ho|Jiang, Jeng-Kae|Chou, Shao-Jiun|Chiang, Tai-Chow|Jan, Hsiang-Shan|Lou, Mary Ann
PMID: 12063967
Journal: Ann Surg Oncol. 2002 Jul;9(6):555-61.
Title: hMLH1 and hMSH2 gene mutation in Brazilian families with suspected hereditary nonpolyposis colorectal cancer.
Author: Rossi, Benedito Mauro|Lopes, Ademar|Oliveira Ferreira, Fabio|Nakagawa, Wilson Toshihiko|Napoli Ferreira, Claudia C|Casali Da Rocha, Jose C|Simpson, Catarina C|Simpson, Andrew J G
PMID: 12095971
Journal: Cancer Chemother Pharmacol. 2002 Jun;49(6):445-52.
Title: Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins.
Author: Sergent, Catherine|Franco, Noreli|Chapusot, Caroline|Lizard-Nacol, Sarab|Isambert, Nicolas|Correia, Maria|Chauffert, Bruno
PMID: 12107548
Journal: Jpn J Clin Oncol. 2002 Jun;32(6):215-8.
Title: A novel germline mutation of hMLH1 in a patient with hereditary non-polyposis colorectal cancer.
Author: Gonda, Kenji|Nomizu, Tadashi|Fukayama, Noriko|Sugano, Kokichi|Takenosita, Seiichi
PMID: 12110639
Journal: Hum Mutat. 2002 Jul;20(1):20-7.
Title: Hereditary non-polyposis colorectal cancer (HNPCC): phenotype-genotype correlation between patients with and without identified mutation.
Author: Bisgaard, Marie Luise|Jager, Anne Charlotte|Myrhoj, Torben|Bernstein, Inge|Nielsen, Finn Cilius
PMID: 12112654
Journal: Trends Mol Med. 2002 Jul;8(7):346-53.
Title: Mouse models for human DNA mismatch-repair gene defects.
Author: Wei, Kaichun|Kucherlapati, Raju|Edelmann, Winfried
PMID: 12114115
Journal: Int J Cancer. 2002 Jun 10;99(5):697-704.
Title: MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers.
Author: Whelan, Alison J|Babb, Sheri|Mutch, David G|Rader, Janet|Herzog, Thomas J|Todd, Christina|Ivanovich, Jennifer L|Goodfellow, Paul J
PMID: 12115503
Journal: Mod Pathol. 2002 Jul;15(7):741-9.
Title: Immunohistochemical pattern of MLH1/MSH2 expression is related to clinical and pathological features in colorectal adenocarcinomas with microsatellite instability.
Author: Lanza, Giovanni|Gafa, Roberta|Maestri, Iva|Santini, Alessandra|Matteuzzi, Maurizio|Cavazzini, Luigi
PMID: 12118112
Journal: Ann Pathol. 2002 Apr;22(2):102-12.
Title: [Immunohistochemistry and genotype analysis of tumors. First part: Which future for the immunochemical diagnosis of cancer?].
Author: Svrcek, Magali|Sabourin, Jean-Christophe
PMID: 12124491
Journal: Gastroenterol Clin North Am. 2002 Jun;31(2):565-86.
Title: Colon cancer: detection and prevention.
Author: Loren, David E|Lewis, James|Kochman, Michael L
PMID: 12134619
Journal: J Cutan Pathol. 2002 Aug;29(7):415-20.
Title: Microsatellite instability and immunostaining for MSH-2 and MLH-1 in cutaneous and internal tumors from patients with the Muir-Torre syndrome.
Author: Machin, Pilar|Catasus, Lluis|Pons, Cristina|Munoz, Josefina|Conde-Zurita, Jose Maria|Balmana, Judith|Barnadas, Maria|Marti, Rosa M|Prat, Jaime|Matias-Guiu, Xavier
PMID: 12139636
Journal: Zhonghua Wai Ke Za Zhi. 2002 Jun;40(6):411-3.
Title: [Genealogical research of hereditary nonpolyposis colorectal cancer].
Author: Wang, Zhenjun|Zhao, Bo|Xu, Yufeng|Wan, Yuanlian|Bu, Dingfang|Huang, Yanting
PMID: 12139794
Journal: Bull Acad Natl Med. 2002;186(2):421-43; discussion 443-5.
Title: [Recent notions on intestinal cancerogenesis, their implications in genetic risk screening and preventive action of non-steroid anti-inflammatory agents].
Author: Couturier, Daniel
PMID: 12145848
Journal: Chin Med J (Engl). 2002 Jul;115(7):1048-52.
Title: Increased sensitivity of colorectal cancer cell lines with microsatellite instability to 5-fluorouracil in vitro.
Author: Chen, Xiuxu|Lai, Mao-de|Huang, Qiong
PMID: 12150741
Journal: Anticancer Res. 2002 Jul-Aug;22(4):2083-8.
Title: Mismatch repair, p53 and beta-catenin proteins in colorectal cancer.
Author: Valentini, Anna Maria|Renna, Letizia|Armentano, Raffele|Pirrelli, Michele|Di Leo, Alfredo|Gentile, Mattia|Caruso, Maria Lucia
PMID: 12174887
Journal: Br J Cancer. 2002 Aug 12;87(4):441-5.
Title: Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma.
Author: Andachi, H|Yashima, K|Koda, M|Kawaguchi, K|Kitamura, A|Hosoda, A|Kishimoto, Y|Shiota, G|Ito, H|Makino, M|Kaibara, N|Kawasaki, H|Murawaki, Y
PMID: 12177781
Journal: Gastroenterology. 2002 Sep;123(3):862-76.
Title: Emerging concepts in colorectal neoplasia.
Author: Jass, Jeremy R|Whitehall, Vicki L J|Young, Joanne|Leggett, Barbara A
PMID: 12198712
Journal: J Cancer Res Clin Oncol. 2002 Aug;128(8):403-11.
Title: Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.
Author: Ward, Robyn|Meldrum, Cliff|Williams, Rachael|Mokany, Elisa|Scott, Rodney|Turner, Jenny|Hawkins, Nicholas|Burgess, Bronwyn|Groombridge, Claire|Spigelman, Allan
PMID: 12200596
Journal: Genes Chromosomes Cancer. 2002 Sep;35(1):1-10.
Title: Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers.
Author: Furukawa, Taiji|Konishi, Fumio|Masubuchi, Shigehiko|Shitoh, Kazuhisa|Nagai, Hideo|Tsukamoto, Toshihiko
PMID: 12203784
Journal: Int J Cancer. 2002 Sep 1;101(1):23-31.
Title: Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.
Author: Magrini, Roberta|Bhonde, Mandar R|Hanski, Marie-Luise|Notter, Michael|Scherubl, Hans|Boland, C Richard|Zeitz, Martin|Hanski, Christoph
PMID: 12209584
Journal: Int J Cancer. 2002 Oct 10;101(5):403-8.
Title: Are there two sides to colorectal cancer?
Author: Iacopetta, Barry
PMID: 12216066
Journal: Clin Cancer Res. 2002 Sep;8(9):2985-91.
Title: Base excision repair as a therapeutic target in colon cancer.
Author: Liu, Lili|Nakatsuru, Yoko|Gerson, Stanton L
PMID: 12231545
Journal: Lakartidningen. 2002 Aug 22;99(34):3296-300.
Title: [Essential to discover hereditary colorectal and endometrial cancer. Mutations in "HNPCC individuals" can cause several different tumors].
Author: Nilbert, Mef|Gronberg, Henrik|Lindblom, Annika
PMID: 12362848
Journal: Br J Cancer. 2002 Oct 7;87(8):892-7.
Title: Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach.
Author: Gille, J J P|Hogervorst, F B L|Pals, G|Wijnen, J Th|van Schooten, R J|Dommering, C J|Meijer, G A|Craanen, M E|Nederlof, P M|de Jong, D|McElgunn, C J|Schouten, J P|Menko, F H
PMID: 12373605
Journal: Gut. 2002 Nov;51(5):677-84.
Title: Transient mismatch repair gene transfection for functional analysis of genetic hMLH1 and hMSH2 variants.
Author: Brieger, A|Trojan, J|Raedle, J|Plotz, G|Zeuzem, S
PMID: 12377806
Journal: World J Gastroenterol. 2002 Oct;8(5):837-40.
Title: Analysis for phenotype of HNPCC in China.
Author: Song, Yong-Mao|Zheng, Shu
PMID: 12378626
Journal: BMC Cancer. 2002 Oct 14;2:25.
Title: Predominance of CIN versus MSI in the development of rectal cancer at young age.
Author: Fernebro, Eva|Halvarsson, Britta|Baldetorp, Bo|Nilbert, Mef
PMID: 12379157
Journal: Int J Cancer. 2002 Nov 10;102(2):166-71.
Title: After hMSH2 and hMLH1--what next? Analysis of three-generational, population-based, early-onset colorectal cancer families.
Author: Jenkins, Mark A|Baglietto, Laura|Dite, Gillian S|Jolley, Damien J|Southey, Melissa C|Whitty, Jonathan|Mead, Leeanne J|St John, D James B|Macrae, Finlay A|Bishop, D Timothy|Venter, Deon J|Giles, Graham G|Hopper, John L
PMID: 12385013
Journal: Leuk Lymphoma. 2002 Aug;43(8):1619-26.
Title: Analysis of mismatch repair defects in the familial occurrence of lymphoma and colorectal cancer.
Author: Teruya-Feldstein, J|Greene, J|Cohen, L|Popplewell, L|Ellis, Nathan A|Offit, K
PMID: 12400605
Journal: Cancer. 2002 Nov 1;95(9):1848-56.
Title: Comparison of selection strategies for genetic testing of patients with hereditary nonpolyposis colorectal carcinoma: effectiveness and cost-effectiveness.
Author: Reyes, Carolina M|Allen, Brian A|Terdiman, Jonathan P|Wilson, Leslie S
PMID: 12404277
Journal: Cancer Res. 2002 Nov 1;62(21):6011-4.
Title: Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.
Author: Whitehall, Vicki L J|Wynter, Coral V A|Walsh, Michael D|Simms, Lisa A|Purdie, David|Pandeya, Nirmala|Young, Joanne|Meltzer, Stephen J|Leggett, Barbara A|Jass, Jeremy R
PMID: 12414620
Journal: J Med Genet. 2002 Nov;39(11):785-9.
Title: Screening for microsatellite instability target genes in colorectal cancers.
Author: Vilkki, S|Launonen, V|Karhu, A|Sistonen, P|Vastrik, I|Aaltonen, L A
PMID: 12414815
Journal: Am J Epidemiol. 2002 Nov 15;156(10):885-902.
Title: Mismatch repair genes hMLH1 and hMSH2 and colorectal cancer: a HuGE review.
Author: Mitchell, R J|Farrington, S M|Dunlop, M G|Campbell, H
PMID: 12419761
Journal: Cancer. 2002 Dec 1;95(11):2422-30.
Title: Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing.
Author: Christensen, Mariann|Katballe, Niels|Wikman, Friedrik|Primdahl, Hanne|Sorensen, Flemming B|Laurberg, Soren|Orntoft, Torben F
PMID: 12436451
Journal: Int J Cancer. 2002 Dec 20;102(6):655-9.
Title: Very low incidence of microsatellite instability in intraductal papillary-mucinous neoplasm of the pancreas.
Author: Nakata, Bunzo|Yashiro, Masakazu|Nishioka, Nobuaki|Aya, Makoto|Yamada, Shinobu|Takenaka, Chiemi|Ohira, Masaichi|Ishikawa, Tetsuro|Nishino, Hiroji|Wakasa, Kenichi|Seki, Shuichi|Hirakawa, Kosei
PMID: 12448010
Journal: Cancer Res. 2002 Dec 1;62(23):6796-802.
Title: Frequent microsatellite instability in sporadic tumors of the upper urinary tract.
Author: Hartmann, Arndt|Zanardo, Livia|Bocker-Edmonston, Tina|Blaszyk, Hagen|Dietmaier, Wolfgang|Stoehr, Robert|Cheville, John C|Junker, Kerstin|Wieland, Wolf|Knuechel, Ruth|Rueschoff, Josef|Hofstaedter, Ferdinand|Fishel, Richard
PMID: 12460887
Journal: Best Pract Res Clin Obstet Gynaecol. 2002 Oct;16(5):703-13.
Title: Hereditary risk of women's cancers.
Author: Frank, Thomas S|Critchfield, Gregory C
PMID: 12475549
Journal: Gastroenterol Clin North Am. 2002 Dec;31(4):971-99.
Title: Chemoprevention of colorectal cancer: problems, progress, and prospects.
Author: Viner, Jaye L|Umar, Asad|Hawk, Ernest T
PMID: 12489273
Journal: Gastroenterol Clin North Am. 2002 Dec;31(4):1107-31.
Title: Heritable colorectal cancer syndromes: recognition and preventive management.
Author: Boardman, Lisa A
PMID: 12489281
Journal: Med Clin North Am. 2002 Nov;86(6):1467-95.
Title: The molecular and genetic basis of colon cancer.
Author: Robbins, David H|Itzkowitz, Steven H
PMID: 12510461
Journal: Genet Test. 2002 Winter;6(4):319-22.
Title: An intronic polymorphism of the hMLH1 gene contributes toward incomplete genetic testing for HNPCC.
Author: Andrew, Susan E|Whiteside, Darcy|Buzin, Carolyn|Greenberg, Cheryl|Spriggs, Elizabeth
PMID: 12537657
Journal: Pathology. 2002 Dec;34(6):529-33.
Title: Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes.
Author: Young, Joanne|Barker, Melissa|Fraser, Leigh|Walsh, Michael D|Spring, Kevin|Biden, Kelli G|Hopper, John L|Leggett, Barbara A|Jass, Jeremy R
PMID: 12555990
Journal: Pathology. 2002 Dec;34(6):541-7.
Title: Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours.
Author: Ruszkiewicz, Andrew|Bennett, Graeme|Moore, James|Manavis, Jim|Rudzki, Barney|Shen, Linda|Suthers, Graeme
PMID: 12555992
Journal: Pathol Int. 2002 Dec;52(12):764-8.
Title: Profile of methylated CpG sites of hMLH1 promoter in primary gastric carcinoma with microsatellite instability.
Author: Kang, Gyeong Hoon|Lee, Sun|Shim, Yhong Hee|Kim, Jin Cheon|Ro, Jae Y
PMID: 12588445
Journal: Curr Opin Gastroenterol. 2002 Jan;18(1):68-73.
Title: Epigenetics in colorectal cancer.
Author: Shen, Lanlan|Issa, Jean-Pierre J
PMID: 17031233
Journal: Genes Chromosomes Cancer. 2003 Jan;36(1):17-25.
Title: Methylation profile of the MLH1 promoter region and their relationship to colorectal carcinogenesis.
Author: Miyakura, Yasuyuki|Sugano, Kokichi|Konishi, Fumio|Fukayama, Noriko|Igarashi, Seiji|Kotake, Kenjiro|Matsui, Takashi|Koyama, Yasuo|Maekawa, Masato|Nagai, Hideo
PMID: 12461746
Journal: Int J Oncol. 2003 Jan;22(1):41-9.
Title: Combined deficiency of hMLH1, hMSH2, hMSH3 and hMSH6 is an independent prognostic factor in colorectal cancer.
Author: Jansson, Agneta|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 12469183
Journal: Mol Cell Biol. 2003 Jan;23(1):206-15.
Title: Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
Author: Kondo, Yutaka|Shen, LanLan|Issa, Jean-Pierre J
PMID: 12482974
Journal: Am J Surg Pathol. 2003 Jan;27(1):65-81.
Title: Morphologic reappraisal of serrated colorectal polyps.
Author: Torlakovic, Emina|Skovlund, Eva|Snover, Dale C|Torlakovic, Goran|Nesland, Jahn M
PMID: 12502929
Journal: Eur J Cancer. 2003 Jan;39(2):240-8.
Title: Defective mismatch-repair in patients with multiple primary tumours including colorectal cancer.
Author: Ericson, K|Halvarsson, B|Nagel, J|Rambech, E|Planck, M|Piotrowska, Z|Olsson, H|Nilbert, M
PMID: 12509957
Journal: Biochem J. 2003 Apr 1;371(Pt 1):183-9.
Title: Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function.
Author: Quaresima, Barbara|Alifano, Pietro|Tassone, Pierfrancesco|Avvedimento, Enrico V|Costanzo, Francesco S|Venuta, Salvatore
PMID: 12513688
Journal: Hum Genet. 2003 Feb;112(2):105-9. Epub 2002 Nov 21.
Title: Two mismatch repair gene mutations found in a colon cancer patient--which one is pathogenic?
Author: Kariola, Reetta|Otway, Robyn|Lonnqvist, Karin E|Raevaara, Tiina E|Macrae, Finlay|Vos, Yvonne J|Kohonen-Corish, Maija|Hofstra, Robert M W|Nystrom-Lahti, Minna
PMID: 12522549
Journal: Clin Cancer Res. 2003 Jan;9(1):383-90.
Title: A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells.
Author: Goel, Ajay|Chang, Dong Kyung|Ricciardiello, Luigi|Gasche, Christoph|Boland, C Richard
PMID: 12538492
Journal: Am J Pathol. 2003 Feb;162(2):469-77.
Title: Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.
Author: Hendriks, Yvonne|Franken, Patrick|Dierssen, Jan Willem|De Leeuw, Wiljo|Wijnen, Juul|Dreef, Enno|Tops, Carli|Breuning, Martijn|Brocker-Vriends, Annette|Vasen, Hans|Fodde, Riccardo|Morreau, Hans
PMID: 12547705
Journal: Br J Cancer. 2003 Feb 10;88(3):413-9.
Title: CpG island methylation is a common finding in colorectal cancer cell lines.
Author: Suter, C M|Norrie, M|Ku, S L|Cheong, K F|Tomlinson, I|Ward, R L
PMID: 12569385
Journal: Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1914-9.
Title: Identification of frame-shift intermediate mutant cells.
Author: Gasche, Christoph|Chang, Christina L|Natarajan, Loki|Goel, Ajay|Rhees, Jennifer|Young, Dennis J|Arnold, Christian N|Boland, C Richard
PMID: 12578960
Journal: Oncol Rep. 2003 Mar-Apr;10(2):483-6.
Title: Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation.
Author: Shin, Joo-Ho|Ku, Ja-Lok|Shin, Ki-Hyuk|Shin, Young-Kyoung|Kang, Sung-Bum|Park, Jae-Gahb
PMID: 12579293
Journal: Cancer Res. 2003 Feb 15;63(4):787-92.
Title: Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.
Author: Ricciardiello, Luigi|Goel, Ajay|Mantovani, Vilma|Fiorini, Tania|Fossi, Stefania|Chang, Dong K|Lunedei, Veronica|Pozzato, Paolo|Zagari, Rocco M|De Luca, Luca|Fuccio, Lorenzo|Martinelli, Giuseppe N|Roda, Enrico|Boland, C Richard|Bazzoli, Franco
PMID: 12591727
Journal: J Am Coll Surg. 2003 Feb;196(2):222-5.
Title: A636P is associated with early-onset colon cancer in Ashkenazi Jews.
Author: Guillem, Jose G|Rapaport, Beth S|Kirchhoff, Tomas|Kolachana, Prema|Nafa, Khedoudja|Glogowski, Emily|Finch, Rob|Huang, Helen|Foulkes, William D|Markowitz, Arnold|Ellis, Nathan A|Offit, Kenneth
PMID: 12595050
Journal: Am J Pathol. 2003 Mar;162(3):815-22.
Title: Frequent CpG island methylation in serrated adenomas of the colorectum.
Author: Park, Seun-Ja|Rashid, Asif|Lee, Jae-Hyuk|Kim, Sang Geol|Hamilton, Stanley R|Wu, Tsung-Teh
PMID: 12598316
Journal: Appl Immunohistochem Mol Morphol. 2003 Mar;11(1):73-7.
Title: The immunohistochemical detection of mismatch repair gene proteins (MLH1, MSH2, MSH6, and PMS2): practical aspects in antigen retrieval and biotin blocking protocols.
Author: Manavis, Jim|Gilham, Peter|Davies, Ruth|Ruszkiewicz, Andrew
PMID: 12610360
Journal: Gastroenterology. 2003 Mar;124(3):626-33.
Title: P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53.
Author: Shen, Lanlan|Kondo, Yutaka|Hamilton, Stanley R|Rashid, Asif|Issa, Jean-Pierre J
PMID: 12612901
Journal: J Med Genet. 2003 Mar;40(3):e30.
Title: Frequent genomic disorganisation of MLH1 in hereditary non-polyposis colorectal cancer (HNPCC) screened by RT-PCR on puromycin treated samples.
Author: Sumitsuji, I|Sugano, K|Matsui, T|Fukayama, N|Yamaguchi, K|Akasu, T|Fujita, S|Moriya, Y|Yokoyama, R|Nomura, S|Yoshida, T|Kodama, T|Ogawa, M
PMID: 12624159
Journal: Dis Colon Rectum. 2003 Mar;46(3):305-12.
Title: Early-age-at-onset colorectal cancer and microsatellite instability as markers of hereditary nonpolyposis colorectal cancer.
Author: Pucciarelli, Salvatore|Agostini, Marco|Viel, Alessandra|Bertorelle, Roberta|Russo, Valentina|Toppan, Paola|Lise, Mario
PMID: 12626904
Journal: Cancer. 2003 Mar 15;97(6):1421-7.
Title: Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age.
Author: Kakar, Sanjay|Burgart, Lawrence J|Thibodeau, Stephen N|Rabe, Kari G|Petersen, Gloria M|Goldberg, Richard M|Lindor, Noralane M
PMID: 12627505
Journal: Cancer. 2003 Mar 15;97(6):1551-7.
Title: Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine.
Author: Planck, Maria|Ericson, Kajsa|Piotrowska, Zofia|Halvarsson, Britta|Rambech, Eva|Nilbert, Mef
PMID: 12627520
Journal: Clin Cancer Res. 2003 Mar;9(3):1112-7.
Title: High incidence of microsatellite instability in colorectal cancer from African Americans.
Author: Ashktorab, Hassan|Smoot, Duane T|Carethers, John M|Rahmanian, Majid|Kittles, Rick|Vosganian, Greg|Doura, Menaham|Nidhiry, Emmanel|Naab, Tammy|Momen, Bahram|Shakhani, Shahid|Giardiello, Francis M
PMID: 12631615
Journal: Am J Gastroenterol. 2003 Mar;98(3):664-70.
Title: Multiple primary cancer, including transitional cell carcinoma of the upper uroepithelial tract in a multigeneration HNPCC family: molecular genetic, diagnostic, and management implications.
Author: Lynch, Henry T|Taylor, Rodney J|Lynch, Jane F|Knezetic, Joseph A|Barrows, Ali|Fodde, Riccardo|Wijnen, Juul|Wagner, Anja
PMID: 12650804
Journal: Hum Mutat. 2003 Apr;21(4):446-7.
Title: Genetic analysis of familial colorectal cancer in Israeli Arabs.
Author: Chen-Shtoyerman, Rakefet|Theodor, Livia|Harmati, Ester|Friedman, Eitan|Dacka, Samir|Kopelman, Yael|Sternberg, Amos|Zarivach, Raz|Bar-Meir, Simon|Fireman, Zvi
PMID: 12655564
Journal: Hum Mutat. 2003 Apr;21(4):449.
Title: Novel MLH1 and MSH2 germline mutations in the first HNPCC families identified in Slovakia.
Author: Bartosova, Zdena|Fridrichova, Ivana|Bujalkova, Maria|Wolf, Brigitte|Ilencikova, Denisa|Krizan, Peter|Hlavcak, Peter|Palaj, Julius|Lukac, Ludovit|Lukacova, Margita|Boor, Andrej|Haider, Ritva|Jiricny, Josef|Nystrom-Lahti, Minna|Marra, Giancarlo
PMID: 12655568
Journal: Cancer Genet Cytogenet. 2003 Apr 1;142(1):13-20.
Title: Three new mutations in hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay.
Author: Sarroca, Carlos|Peltomaki, Paivi|Alfano, Nora|Tedesco, Gladys|Della Valle, Adriana|Dominguez, Alejandra|Lynch, Henry T
PMID: 12660027
Journal: Ann Intern Med. 2003 Apr 1;138(7):560-70.
Title: The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications.
Author: Chung, Daniel C|Rustgi, Anil K
PMID: 12667026
Journal: Gastroenterology. 2003 Apr;124(4):1165-6.
Title: Gender difference for promoter methylation pattern of hMLH1 and p16 in sporadic MSI colorectal cancer.
Author: Laghi, Luigi|Bianchi, Paolo|Malesci, Alberto
PMID: 12671921
Journal: Int J Colorectal Dis. 2003 May;18(3):196-202.
Title: Methylation of the hMLH1 and hMSH2 promoter in early-onset sporadic colorectal carcinomas with microsatellite instability.
Author: Kim, Hee C|Kim, Chang N|Yu, Chang S|Roh, Seon A|Kim, Jin C
PMID: 12673483
Journal: Clin Genet. 2003 Mar;63(3):215-8.
Title: Identification of a deletion in the mismatch repair gene, MSH2, using mouse-human cell hybrids monosomal for chromosome 2.
Author: Pyatt, R E|Nakagawa, H|Hampel, H|Sedra, M|Fuchik, M B|Comeras, I|de la Chapelle, A|Prior, T W
PMID: 12694232
Journal: Mol Cell Biol. 2003 May;23(9):3320-8.
Title: Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha.
Author: Wu, Xiaosheng|Platt, Jeffrey L|Cascalho, Marilia
PMID: 12697830
Journal: Cancer Res. 2003 Apr 15;63(8):1894-9.
Title: The role of hMLH3 in familial colorectal cancer.
Author: Liu, Hong-Xu|Zhou, Xiao-Lei|Liu, Tao|Werelius, Barbro|Lindmark, Gudrun|Dahl, Niklas|Lindblom, Annika
PMID: 12702580
Journal: Int J Cancer. 2003 Jul 1;105(4):484-90.
Title: Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability.
Author: Catto, James W F|Xinarianos, George|Burton, Julian L|Meuth, Mark|Hamdy, Freddie C
PMID: 12712438
Journal: Cancer. 2003 May 1;97(9):2273-8.
Title: Reduced expression of hMSH2 protein is correlated to poor survival for soft tissue sarcoma patients.
Author: Taubert, Helge W|Bartel, Frank|Kappler, Matthias|Schuster, Katja|Meye, Axel|Lautenschlager, Christine|Thamm-Mucke, Barbara|Bache, Matthias|Schmidt, Hannelore|Holzhausen, Hans-Jurgen|Wurl, Peter
PMID: 12712483
Journal: Proc Natl Acad Sci U S A. 2003 May 13;100(10):5908-13. Epub 2003 May 5.
Title: Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers.
Author: Goodfellow, Paul J|Buttin, Barbara M|Herzog, Thomas J|Rader, Janet S|Gibb, Randall K|Swisher, Elizabeth|Look, Katherine|Walls, Ken C|Fan, Ming-Yu|Mutch, David G
PMID: 12732731
Journal: Gut. 2003 Jun;52(6):898-9.
Title: Rapidly progressive adenomatous polyposis in a patient with germline mutations in both the APC and MLH1 genes: the worst of two worlds.
Author: Scheenstra, R|Rijcken, F E M|Koornstra, J J|Hollema, H|Fodde, R|Menko, F H|Sijmons, R H|Bijleveld, C M A|Kleibeuker, J H
PMID: 12740349
Journal: Arch Pathol Lab Med. 2003 Jun;127(6):694-700.
Title: Microsatellite instability in colorectal carcinoma. The comparison of immunohistochemistry and molecular biology suggests a role for hMSH6 [correction of hMLH6] immunostaining.
Author: Rigau, Valerie|Sebbagh, Nicole|Olschwang, Sylviane|Paraf, Francois|Mourra, Najat|Parc, Yann|Flejou, Jean-Francois
PMID: 12741892
Journal: Cancer Lett. 2003 Jun 10;195(2):243-51.
Title: Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines.
Author: Chang, Dong Kyung|Goel, Ajay|Ricciardiello, Luigi|Lee, Dong Ho|Chang, Christina L|Carethers, John M|Boland, C Richard
PMID: 12767533
Journal: Am Surg. 2003 May;69(5):387-91; discussion 391-2.
Title: Genetic testing for hereditary nonpolyposis colorectal cancer.
Author: Hoedema, Rebecca|Monroe, Thomas|Bos, Cindy|Palmer, Sharon|Kim, Donald|Marvin, Monica|Luchtefeld, Martin
PMID: 12769209
Journal: Zhonghua Wai Ke Za Zhi. 2003 Feb;41(2):112-5.
Title: [Clinicopathological features of typical and non-typical hereditary non-polyposis colorectal cancer and their germline mutation of hMLH1 and hMSH2].
Author: Cui, Long|Jin, Hei-Ying|Meng, Rong-Gui|Yan, Yu-Di|Wang, Jin-Sui|Liu, Fei|Xu, Hong-Lian|Yu, De-Hong
PMID: 12783672
Journal: Oncol Rep. 2003 Jul-Aug;10(4):859-66.
Title: Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene.
Author: Yamada, Kanae|Zhong, Xiaoling|Kanazawa, Shinsaku|Koike, Junichi|Tsujita, Kazunori|Hemmi, Hiromichi
PMID: 12792735
Journal: Int J Cancer. 2003 Aug 10;106(1):66-73.
Title: Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.
Author: Arnold, Christian N|Goel, Ajay|Boland, C Richard
PMID: 12794758
Journal: Clin Cancer Res. 2003 Jun;9(6):2327-34.
Title: DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells.
Author: Yan, Tao|Berry, Suzanne E|Desai, Anand B|Kinsella, Timothy J
PMID: 12796402
Journal: Int J Cancer. 2003 Aug 20;106(2):292-6.
Title: Little evidence for involvement of MLH3 in colorectal cancer predisposition.
Author: Hienonen, Tuija|Laiho, Paivi|Salovaara, Reijo|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Sistonen, Pertti|Peltomaki, Paivi|Lehtonen, Rainer|Nupponen, Nina N|Launonen, Virpi|Karhu, Auli|Aaltonen, Lauri A
PMID: 12800209
Journal: Int J Gynecol Cancer. 2003 May-Jun;13(3):352-60.
Title: Cancer history and loss of MSH2 and MLH1 protein expression in patients with endometrial hyperplasia.
Author: Maruyama, A|Saito, T|Hachitanda, Y|Tsukamoto, N
PMID: 12801268
Journal: Virchows Arch. 2003 Aug;443(2):115-21.
Title: Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression.
Author: Jourdan, Florence|Sebbagh, Nicole|Comperat, Eva|Mourra, Najat|Flahault, Antoine|Olschwang, Sylviane|Duval, Alex|Hamelin, Richard|Flejou, Jean-Francois
PMID: 12802583
Journal: J Korean Med Sci. 2003 Jun;18(3):387-91.
Title: Characterization of mutator pathway in younger-age-onset colorectal adenocarcinomas.
Author: Roh, Seon Ae|Kim, Hee Cheol|Kim, Jung Seon|Kim, Jin Cheon
PMID: 12808326
Journal: Cancer Res. 2003 Jun 15;63(12):3133-7.
Title: Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Author: van Engeland, Manon|Weijenberg, Matty P|Roemen, Guido M J M|Brink, Mirian|de Bruine, Adriaan P|Goldbohm, R Alexandra|van den Brandt, Piet A|Baylin, Stephen B|de Goeij, Anton F P M|Herman, James G
PMID: 12810640
Journal: Cancer Res. 2003 Jun 15;63(12):3302-8.
Title: A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations.
Author: Kondo, Emiko|Suzuki, Hideyuki|Horii, Akira|Fukushige, Shinichi
PMID: 12810663
Journal: Anticancer Res. 2003 Mar-Apr;23(2C):1773-7.
Title: Relationship between microsatellite instability, response and survival in palliative patients with colorectal cancer undergoing first-line chemotherapy.
Author: Brueckl, W M|Moesch, C|Brabletz, T|Koebnick, C|Riedel, C|Jung, A|Merkel, S|Schaber, S|Boxberger, F|Kirchner, T|Hohenberger, W|Hahn, E G|Wein, A
PMID: 12820457
Journal: Cancer. 2003 Jul 1;98(1):48-54.
Title: Evidence of a preferred molecular pathway in patients with synchronous colorectal cancer.
Author: Dykes, Sharon L|Qui, Hongming|Rothenberger, David A|Garcia-Aguilar, Julio
PMID: 12833454
Journal: Gut. 2003 Aug;52(8):1140-7.
Title: Prevalence and incidence of hyperplastic polyps and adenomas in familial colorectal cancer: correlation between the two types of colon polyps.
Author: Liljegren, A|Lindblom, A|Rotstein, S|Nilsson, B|Rubio, C|Jaramillo, E
PMID: 12865272
Journal: Electrophoresis. 2003 Jul;24(14):2316-21.
Title: A single-strand conformation polymorphism method by capillary electrophoresis with laser-induced fluorescence for detection of the T1151A mutation in hMLH1 gene.
Author: Shi, Xianzhe|Xu, Guowang|Zhao, Chunxia|Ma, Jianmei|Zhang, Yan|Lv, Shen|Yang, Qing
PMID: 12874865
Journal: Gastroenterology. 2003 Aug;125(2):501-9.
Title: Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein.
Author: Raevaara, Tiina E|Vaccaro, Carlos|Abdel-Rahman, Wael M|Mocetti, Esteban|Bala, Shashi|Lonnqvist, Karin E|Kariola, Reetta|Lynch, Henry T|Peltomaki, Paivi|Nystrom-Lahti, Minna
PMID: 12891553
Journal: Dis Colon Rectum. 2003 Aug;46(8):1069-77.
Title: Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers.
Author: Jeong, Seung-Yong|Shin, Ki-Hyuk|Shin, Joo-Ho|Ku, Ja-Lok|Shin, Young-Kyoung|Park, So-Yeon|Kim, Woo-Ho|Park, Jae-Gahb
PMID: 12907901
Journal: Br J Cancer. 2003 Aug 18;89(4):707-12.
Title: Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma.
Author: Matsumoto, N|Yoshida, T|Yamashita, K|Numata, Y|Okayasu, I
PMID: 12915883
Journal: Clin Genet. 2003 Sep;64(3):220-7.
Title: Germline hMLH1 promoter mutation in a Newfoundland HNPCC kindred.
Author: Green, R C|Green, A G|Simms, M|Pater, A|Robb, J D|Green, J S
PMID: 12919137
Journal: Clin Genet. 2003 Sep;64(3):243-51.
Title: Low mutation rate of hMSH2 and hMLH1 in Taiwanese hereditary non-polyposis colorectal cancer.
Author: Wei, S-C|Yu, C-Y|Tsai-Wu, J-J|Su, Y-N|Sheu, J-C|Wu, C-H H|Wang, C-Y|Wong, J-M
PMID: 12919140
Journal: J Med Genet. 2003 Aug;40(8):597-600.
Title: Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome.
Author: Plaschke, J|Ruschoff, J|Schackert, H K
PMID: 12920072
Journal: Zhonghua Yi Xue Za Zhi. 2003 Aug 10;83(15):1326-30.
Title: [Mutation analysis on MSH2 and MLH1 genes in patients of colorectal cancer at early age].
Author: Wang, Ya-ping|Zhang, Jun-ni|Li, Jin-tian|Zhou, Jian-nong|Zhang, Xiao-mei|Zhu, Ming
PMID: 12930688
Journal: Hum Mutat. 2003 Sep;22(3):258.
Title: Identification and characterization of genomic rearrangements of MSH2 and MLH1 in Lynch syndrome (HNPCC) by novel techniques.
Author: Nakagawa, Hidewaki|Hampel, Heather|de la Chapelle, Albert
PMID: 12938096
Journal: Mol Cancer Res. 2003 Aug;1(10):747-54.
Title: Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates.
Author: Yanamadala, Sunitha|Ljungman, Mats
PMID: 12939400
Journal: Int J Cancer. 2003 Nov 1;107(2):183-8.
Title: Stromal expression of invasion-promoting, matrix-degrading proteases MMP-1 and -9 and the Ets 1 transcription factor in HNPCC carcinomas and sporadic colorectal cancers.
Author: Behrens, Peter|Mathiak, Micaela|Mangold, Elisabeth|Kirdorf, Simona|Wellmann, Axel|Fogt, Franz|Rothe, Marcus|Florin, Alexandra|Wernert, Nicolas
PMID: 12949792
Journal: Cancer Cell. 2003 Aug;4(2):121-31.
Title: Genetics supersedes epigenetics in colon cancer phenotype.
Author: Yamashita, Kentaro|Dai, Tomoko|Dai, Yuichi|Yamamoto, Fumiichiro|Perucho, Manuel
PMID: 12957287
Journal: Cancer Res. 2003 Sep 1;63(17):5209-12.
Title: BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair.
Author: Wang, Liang|Cunningham, Julie M|Winters, Jennifer L|Guenther, Jennifer C|French, Amy J|Boardman, Lisa A|Burgart, Lawrence J|McDonnell, Shannon K|Schaid, Daniel J|Thibodeau, Stephen N
PMID: 14500346
Journal: Ann Oncol. 2003 Oct;14(10):1530-6.
Title: Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.
Author: Colombino, M|Cossu, A|Arba, A|Manca, A|Curci, A|Avallone, A|Comella, G|Botti, G|Scintu, F|Amoruso, M|D'Abbicco, D|d'Agnessa, M R|Spanu, A|Tanda, F|Palmieri, G
PMID: 14504054
Journal: Cancer. 2003 Oct 1;98(7):1540-6.
Title: High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas.
Author: Strazzullo, Maria|Cossu, Antonio|Baldinu, Paola|Colombino, Maria|Satta, Maria P|Tanda, Francesco|De Bonis, Maria L|Cerase, Andrea|D'Urso, Michele|D'Esposito, Maurizio|Palmieri, Giuseppe
PMID: 14508843
Journal: Pathol Int. 2003 Oct;53(10):667-70.
Title: Lack of microsatellite instability in neoplasms of ampulla of Vater.
Author: Park, Sunhoo|Kim, Sun Whe|Kim, Sun Hee|Darwish, Nevine S|Kim, Woo Ho
PMID: 14516316
Journal: Hum Mutat. 2003 Nov;22(5):388-94.
Title: High throughput detection of microsatellite instability by denaturing high-performance liquid chromatography.
Author: Pan, Kai-feng|Liu, Wanguo|Lu, You-Yong|Zhang, Lian|Li, Zhen-pu|Lu, Wan-Li|Thibodeau, Stephen N|You, Wei-Cheng
PMID: 14517950
Journal: Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author: Cohen, M Michael Jr
PMID: 14518068
Journal: Int J Cancer. 2003 Nov 20;107(4):571-9.
Title: MSH6 germline mutations are rare in colorectal cancer families.
Author: Peterlongo, Paolo|Nafa, Khedoudja|Lerman, Gabriel S|Glogowski, Emily|Shia, Jinru|Ye, Tian Z|Markowitz, Arnold J|Guillem, Jose G|Kolachana, Prema|Boyd, Jeffrey A|Offit, Kenneth|Ellis, Nathan A
PMID: 14520694
Journal: Cancer Res. 2003 Sep 15;63(18):5738-44.
Title: Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer.
Author: Fallik, David|Borrini, Francesco|Boige, Valerie|Viguier, Jerome|Jacob, Sandrine|Miquel, Catherine|Sabourin, Jean-Christophe|Ducreux, Michel|Praz, Francoise
PMID: 14522894
Journal: J Clin Oncol. 2003 Oct 15;21(20):3729-36.
Title: Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability.
Author: Ward, Robyn Lynne|Cheong, Kay|Ku, Su-Lyn|Meagher, Alan|O'Connor, Terence|Hawkins, Nicholas John
PMID: 14551292
Journal: Br J Cancer. 2003 Oct 20;89(8):1559-65.
Title: Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.
Author: Fedier, A|Fowst, C|Tursi, J|Geroni, C|Haller, U|Marchini, S|Fink, D
PMID: 14562032
Journal: Am J Gastroenterol. 2003 Oct;98(10):2306-11.
Title: Hyperplastic polyps in hereditary nonpolyposis colorectal cancer.
Author: Rijcken, Fleur E M|van der Sluis, Tineke|Hollema, Harry|Kleibeuker, Jan H
PMID: 14572584
Journal: Fam Cancer. 2003;2(1):15-25.
Title: Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility?
Author: Levene, Sara|Scott, Gillian|Price, Patricia|Sanderson, Jeremy|Evans, Helen|Taylor, Claire|Bass, Sylvia|Lewis, Cathryn|Hodgson, Shirley
PMID: 14574163
Journal: Am J Surg Pathol. 2003 Nov;27(11):1393-406.
Title: Histopathology and mismatch repair status of 458 consecutive colorectal carcinomas.
Author: Wright, Cheryl L|Stewart, Ian D
PMID: 14576472
Journal: Cancer Res. 2003 Oct 15;63(20):6935-41.
Title: Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells.
Author: Robinson, Blaine W|Im, Michael M|Ljungman, Mats|Praz, Francoise|Shewach, Donna S
PMID: 14583494
Journal: World J Gastroenterol. 2003 Nov;9(11):2464-8.
Title: Investigation of Epstein-Barr virus in Chinese colorectal tumors.
Author: Liu, Huan-Xin|Ding, Yan-Qing|Li, Xin|Yao, Kai-Tai
PMID: 14606077
Journal: Int J Surg Pathol. 2003 Oct;11(4):253-60.
Title: Microsatellite analysis of early stage (Ia-IIb) uterine cervical squamous carcinoma.
Author: Clarke, B|Gordon, M|Moodley, M|Naidoo, R|Chetty, R
PMID: 14615820
Journal: Am Surg. 2003 Nov;69(11):981-7.
Title: Colorectal malignancies in HIV-positive patients.
Author: Yeguez, Jose F|Martinez, Sergio A|Sands, Dana R|Sands, Laurence R|Hellinger, Michael D
PMID: 14627261
Journal: Cancer Res. 2003 Nov 15;63(22):7563-70.
Title: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Author: Fang, Ming Zhu|Wang, Yimin|Ai, Ni|Hou, Zhe|Sun, Yi|Lu, Hong|Welsh, William|Yang, Chung S
PMID: 14633667
Journal: Korean J Gastroenterol. 2003 Nov;42(5):369-76.
Title: [Is immunohistochemistry for MLH1 and MSH2 proteins a useful method for detection of microsatellite instability in sporadic colorectal cancer?].
Author: Do, Jae Hyuk|Chang, Sae Kyung|Ahnn, Ji Yong|Cha, Bong Ki|Cheong, Seung Moon|Kim, Dae Won|Cheong, Hey Ryung|Kim, Hyung Joon|Kim, Jae Gyu|Lee, Tae Jin|Park, Eon Sub|Park, Sill Moo
PMID: 14646573
Journal: Cancer Epidemiol Biomarkers Prev. 2003 Nov;12(11 Pt 1):1130-6.
Title: Dietary factors and microsatellite instability in sporadic colon carcinomas.
Author: Diergaarde, Brenda|Braam, Hanneke|van Muijen, Goos N P|Ligtenberg, Marjolijn J L|Kok, Frans J|Kampman, Ellen
PMID: 14652271
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Dec;20(6):517-21.
Title: [Large deletion in mismatch repair genes uncovered by quantitative multiplex PCR-high performance liquid chromatography system].
Author: Wang, Ya-ping|Zhu, Ming|Sun, Meng-hong|Li, Jin-tian|Zhang, Jun-ni|Zhang, Xiao-mei|Liu, Xiao-rong
PMID: 14669222
Journal: Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):5860-5.
Title: The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase.
Author: Kawakami, Kazuyuki|Ruszkiewicz, Andrew|Bennett, Graeme|Moore, James|Watanabe, Go|Iacopetta, Barry
PMID: 14676107
Journal: Pathol Oncol Res. 2003;9(4):236-41. Epub 2003 Dec 22.
Title: hMLH1 and hMSH2 somatic inactivation mechanisms in sporadic colorectal cancer patients.
Author: Kamory, Eniko|Kolacsek, Orsolya|Otto, Szabolcs|Csuka, Orsolya
PMID: 14688830
Journal: Clin Cancer Res. 2003 Dec 15;9(17):6410-8.
Title: Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.
Author: Obata, Toshiro|Toyota, Minoru|Satoh, Ayumi|Sasaki, Yasushi|Ogi, Kazuhiro|Akino, Kimishige|Suzuki, Hiromu|Murai, Masafumi|Kikuchi, Takefumi|Mita, Hiroaki|Itoh, Fumio|Issa, Jean-Pierre J|Tokino, Takashi|Imai, Kohzoh
PMID: 14695142
Journal: Hepatogastroenterology. 2003 Nov-Dec;50(54):1749-52.
Title: Sporadic colorectal cancer in elderly people.
Author: Koketsu, Shinichiro|Watanabe, Toshiaki|Tada, Tomohiro|Kanazawa, Takamitsu|Ueda, Eiji|Nagawa, Hirokazu
PMID: 14696396
Journal: Zhonghua Wai Ke Za Zhi. 2003 Nov;41(11):809-11.
Title: [The role of the immunohistochemistry for hMLH1 and hMSH2 with detection of microsatellite instability to identify the kindreds with hereditary nonpolyposis colorectal cancer].
Author: Jin, Hei-ying|Cui, Long|Meng, Rong-gui|Liu, Fei|Yan, Yu-di|Ding, Yi-jiang|Yao, Hang|Fu, Chuan-gang|Yu, De-hong
PMID: 14703452
Journal: Fam Cancer. 2003;2(3-4):169-73.
Title: Are there socio-economic inequalities in age of resection of colorectal cancer in people with HNPCC?
Author: Adams, Jean|White, Martin|Barker, Gail|Mathers, John|Burn, John
PMID: 14707528
Journal: Rev Med Chil. 2003 Nov;131(11):1227-36.
Title: [Microsatellite instability and loss of heterozygosity in neoplastic and preneoplastic gastric lesions].
Author: Roa, Juan Carlos|Araya, Juan Carlos|Villaseca, Miguel Angel|Roa, Ivan|Correa, Pelayo
PMID: 14743682
Journal: Verh Dtsch Ges Pathol. 2003;87:172-84.
Title: [Molecular changes in development and progression of urothelial carcinoma].
Author: Hartmann, A
PMID: 16888910
Journal: Virchows Arch. 2004 Feb;444(2):135-41. Epub 2003 Dec 2.
Title: Microsatellite instability analysis and/or immunostaining for the diagnosis of hereditary nonpolyposis colorectal cancer?
Author: Halvarsson, Britta|Lindblom, Annika|Rambech, Eva|Lagerstedt, Kristina|Nilbert, Mef
PMID: 14652751
Journal: Carcinogenesis. 2004 Apr;25(4):541-7.
Title: Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers.
Author: Chiappini, Franck|Gross-Goupil, Marine|Saffroy, Raphael|Azoulay, Daniel|Emile, Jean-Francois|Veillhan, Luc-Antoine|Delvart, Valerie|Chevalier, Stephan|Bismuth, Henri|Debuire, Brigitte|Lemoine, Antoinette
PMID: 14656944
Journal: Mol Cell Biol. 2004 Jan;24(1):465-74.
Title: The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells.
Author: Russo, Maria Teresa|Blasi, Monica Francesca|Chiera, Federica|Fortini, Paola|Degan, Paolo|Macpherson, Peter|Furuichi, Masato|Nakabeppu, Yusaku|Karran, Peter|Aquilina, Gabriele|Bignami, Margherita
PMID: 14673178
Journal: Gut. 2004 Jan;53(1):115-22.
Title: Aetiology of colorectal cancer and relevance of monogenic inheritance.
Author: Ponz de Leon, M|Benatti, P|Borghi, F|Pedroni, M|Scarselli, A|Di Gregorio, C|Losi, L|Viel, A|Genuardi, M|Abbati, G|Rossi, G|Menigatti, M|Lamberti, I|Ponti, G|Roncucci, L
PMID: 14684585
Journal: Genes Chromosomes Cancer. 2004 Feb;39(2):138-42.
Title: Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation.
Author: Domingo, Enric|Espin, Eloi|Armengol, Manel|Oliveira, Carla|Pinto, Mafalda|Duval, Alex|Brennetot, Caroline|Seruca, Raquel|Hamelin, Richard|Yamamoto, Hiroyuki|Schwartz, Simo Jr
PMID: 14695993
Journal: World J Surg. 2004 Feb;28(2):117-23.
Title: Clinical and molecular biologic characteristics of early-onset versus late-onset colorectal carcinoma in Filipinos.
Author: Uy, Gemma B|Kaw, Leoncio L|Punzalan, Corazon K|Querol, R Ireneo Luis C|Koustova, Elena V|Bowyer, Mark W|Hobbs, Christine M|Sobin, Leslie H|Wherry, David C
PMID: 14708047
Journal: World J Gastroenterol. 2004 Jan 15;10(2):209-13.
Title: Genetic detection of Chinese hereditary nonpolyposis colorectal cancer.
Author: Cui, Long|Jin, Hei-Ying|Cheng, Hui-Yu|Yan, Yu-Di|Meng, Rong-Gui|Yu, De-Hong
PMID: 14716824
Journal: Cancer Biol Ther. 2004 Jan;3(1):73-8. Epub 2004 Jan 5.
Title: Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.
Author: Arnold, Christian N|Goel, Ajay|Compton, Carolyn|Marcus, Victoria|Niedzwiecki, Donna|Dowell, Jeannette M|Wasserman, Linda|Inoue, Toru|Mayer, Robert J|Bertagnolli, Monica M|Boland, C Richard
PMID: 14726676
Journal: Carcinogenesis. 2004 May;25(5):841-6.
Title: Colorectal cancer without high microsatellite instability and chromosomal instability--an alternative genetic pathway to human colorectal cancer.
Author: Tang, Reiping|Changchien, Chung Rong|Wu, Meng-Chih|Fan, Chung-Wei|Liu, Kwang-Wen|Chen, Jinn-Shiun|Chien, Huei-Tzu|Hsieh, Ling-Ling
PMID: 14729584
Journal: Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):191-5.
Title: BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.
Author: Deng, Guoren|Bell, Ian|Crawley, Suzanne|Gum, James|Terdiman, Jonathan P|Allen, Brian A|Truta, Brindusa|Sleisenger, Marvin H|Kim, Young S
PMID: 14734469
Journal: J Lab Clin Med. 2004 Jan;143(1):59-66.
Title: Immunoassay for wild-type protein in lymphocytes predicts germline mutations in patients at risk for hereditary colorectal cancer.
Author: Fields, Jeremy Z|Gao, Zhiping|Gao, Zhenqiang|Lewis, Marcia|Maimonis, Peter|Harvey, Jean|Lynch, Henry T|Boman, Bruce M
PMID: 14749686
Journal: Clin Genet. 2004 Mar;65(3):215-25.
Title: Hereditary non-polyposis colorectal cancer and the role of hPMS2 and hEXO1 mutations.
Author: Thompson, E|Meldrum, C J|Crooks, R|McPhillips, M|Thomas, L|Spigelman, A D|Scott, R J
PMID: 14756672
Journal: Ann Oncol. 2004 Feb;15(2):242-6.
Title: Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer.
Author: Emterling, A|Wallin, A|Arbman, G|Sun, X-F
PMID: 14760116
Journal: Virchows Arch. 2004 Mar;444(3):235-8.
Title: Correlation between patterns of DNA mismatch repair hmlh1 and hmsh2 protein expression and progression of dysplasia in intraductal papillary mucinous neoplasms of the pancreas.
Author: Handra-Luca, Adriana|Couvelard, Anne|Degott, Claude|Flejou, Jean-Francois
PMID: 14760534
Journal: Gastroenterology. 2004 Feb;126(2):576-85.
Title: Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation.
Author: Gallinger, Steven|Aronson, Melyssa|Shayan, Katayoon|Ratcliffe, Elyanne M|Gerstle, Justin T|Parkin, Patricia C|Rothenmund, Heidi|Croitoru, Marina|Baumann, Ewa|Durie, Peter R|Weksberg, Rosanna|Pollett, Aaron|Riddell, Robert H|Ngan, Bo Y|Cutz, Ernest|Lagarde
PMID: 14762794
Journal: Cancer Res. 2004 Feb 1;64(3):864-70.
Title: Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.
Author: Plaschke, Jens|Kruger, Stefan|Jeske, Birgit|Theissig, Franz|Kreuz, Friedmar R|Pistorius, Steffen|Saeger, Hans D|Iaccarino, Ingram|Marra, Giancarlo|Schackert, Hans K
PMID: 14871813
Journal: Clin Cancer Res. 2004 Feb 1;10(3):972-80.
Title: Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.
Author: de Jong, Andrea E|van Puijenbroek, Marjo|Hendriks, Yvonne|Tops, Carli|Wijnen, Juul|Ausems, Margreet G E M|Meijers-Heijboer, Hanne|Wagner, Anja|van Os, Theo A M|Brocker-Vriends, Annette H J T|Vasen, Hans F A|Morreau, Hans
PMID: 14871975
Journal: Gut. 2004 Mar;53(3):371-5.
Title: Prognostic significance of microsatellite instability determined by immunohistochemical staining of MSH2 and MLH1 in sporadic T3N0M0 colon cancer.
Author: Parc, Y|Gueroult, S|Mourra, N|Serfaty, L|Flejou, J-F|Tiret, E|Parc, R
PMID: 14960518
Journal: Int J Cancer. 2004 Apr 10;109(3):370-6.
Title: Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden.
Author: Cederquist, Kristina|Emanuelsson, Monica|Goransson, Ingela|Holinski-Feder, Elke|Muller-Koch, Yvonne|Golovleva, Irina|Gronberg, Henrik
PMID: 14961575
Journal: Lab Invest. 2004 Apr;84(4):493-501.
Title: Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis.
Author: Menon, Anand G|Janssen-van Rhijn, Connie M|Morreau, Hans|Putter, Hein|Tollenaar, Rob A E M|van de Velde, Cornelis J H|Fleuren, Gert Jan|Kuppen, Peter J K
PMID: 14968119
Journal: Hum Mutat. 2004 Mar;23(3):285.
Title: Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.
Author: Plaschke, Jens|Kruger, Stefan|Dietmaier, Wolfgang|Gebert, Johannes|Sutter, Christian|Mangold, Elisabeth|Pagenstecher, Constanze|Holinski-Feder, Elke|Schulmann, Karsten|Moslein, Gabriela|Ruschoff, Josef|Engel, Christoph|Evans, Gareth|Schackert, Hans K
PMID: 14974087
Journal: Cancer. 2004 Mar 1;100(5):913-9.
Title: The replication error phenotype is associated with the development of distant metastases in hormonally treated patients with breast carcinoma.
Author: Chagpar, Anees|Magliocco, Anthony|Kerviche, Annette|Tan, Leonard|Walley, Barbara|DeCoteau, John F
PMID: 14983485
Journal: J Med Genet. 2004 Mar;41(3):e34.
Title: A founder MLH1 mutation in families from the districts of Modena and Reggio-Emilia in northern Italy with hereditary non-polyposis colorectal cancer associated with protein elongation and instability.
Author: Caluseriu, O|Di Gregorio, C|Lucci-Cordisco, E|Santarosa, M|Trojan, J|Brieger, A|Benatti, P|Pedroni, M|Colibazzi, T|Bellacosa, A|Neri, G|Ponz de Leon, M|Viel, A|Genuardi, M
PMID: 14985405
Journal: Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):11-27.
Title: Genomic instability and colon cancer.
Author: Grady, William M
PMID: 15000146
Journal: Int J Oncol. 2004 Apr;24(4):1039-47.
Title: Mutations in DNA mismatch repair genes: implications for DNA damage signaling and drug sensitivity (review).
Author: Fedier, Andre|Fink, Daniel
PMID: 15010846
Journal: J Neurooncol. 2004 Jan;66(1-2):51-7.
Title: Increased hMSH2 protein expression in glioblastoma multiforme.
Author: Srivastava, Tapasya|Chattopadhyay, Parthaprasad|Mahapatra, A K|Sarkar, Chitra|Sinha, Subrata
PMID: 15015769
Journal: Gut. 2004 Apr;53(4):573-80.
Title: Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.
Author: Wynter, C V A|Walsh, M D|Higuchi, T|Leggett, B A|Young, J|Jass, J R
PMID: 15016754
Journal: Mod Pathol. 2004 Jun;17(6):696-700.
Title: Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survival.
Author: Kakar, Sanjay|Aksoy, Saime|Burgart, Lawrence J|Smyrk, Thomas C
PMID: 15017435
Journal: Hum Pathol. 2004 Mar;35(3):335-42.
Title: Standardized approach for microsatellite instability detection in gastric carcinomas.
Author: Musulen, Eva|Moreno, Victor|Reyes, German|Sancho, Francisco Javier|Peinado, Miguel Angel|Esteller, Manel|Herman, James G|Combalia, Neus|Rey, Merce|Capella, Gabriel
PMID: 15017590
Journal: Clin Gastroenterol Hepatol. 2004 Feb;2(2):147-56.
Title: Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability.
Author: Miyakura, Yasuyuki|Sugano, Kokichi|Akasu, Takayuki|Yoshida, Teruhiko|Maekawa, Masato|Saitoh, Soh|Sasaki, Hideyuki|Nomizu, Tadashi|Konishi, Fumio|Fujita, Shin|Moriya, Yoshihiro|Nagai, Hideo
PMID: 15017620
Journal: Cancer Res. 2004 Apr 1;64(7):2434-8.
Title: Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.
Author: Mori, Yuriko|Yin, Jing|Sato, Fumiaki|Sterian, Anca|Simms, Lisa A|Selaru, Florin M|Schulmann, Karsten|Xu, Yan|Olaru, Andreea|Wang, Suna|Deacu, Elena|Abraham, John M|Young, Joanne|Leggett, Barbara A|Meltzer, Stephen J
PMID: 15059896
Journal: Zhonghua Wai Ke Za Zhi. 2004 Feb 7;42(3):158-62.
Title: [Clinical analysis and molecular genetic study of hereditary nonpolyposis colorectal cancer kindreds].
Author: Luo, Ding-cun|Cai, Qi|Sun, Meng-hong|Ni, Yao-zhong|Tao, Chong-wei|Chen, Zhe-jing|Shi, Da-ren
PMID: 15062061
Journal: Oncol Rep. 2004 May;11(5):951-6.
Title: Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer.
Author: Hill, Kalisha A|Wang, Kim L|Stryker, Steven J|Gupta, Rohit|Weinrach, David M|Rao, M S
PMID: 15069531
Journal: Eur J Cancer Prev. 2004 Feb;13(1):27-32.
Title: Tumour spectrum of non-polyposis colorectal cancer (Lynch syndrome) on the island of Tenerife and influence of insularity on the clinical manifestations.
Author: Medina-Arana, V|Barrios, Y|Fernandez-Peralta, A|Jimenez, A|Salido, E|Gonzalez, F|Gonzalez-Aguilera, J J
PMID: 15075785
Journal: Int J Colorectal Dis. 2004 Nov;19(6):561-8. Epub 2004 Apr 9.
Title: Geno- and pheno-typic characterization in ten patients with double-primary gastric and colorectal adenocarcinomas.
Author: Kim, Jin C|Koo, Kum H|Kim, Hee C|Kim, Jung S|Kang, Gyeong H
PMID: 15083323
Journal: J Clin Oncol. 2004 May 1;22(9):1736-42.
Title: Individuals with an increased risk of colorectal cancer: perceived benefits and psychological aspects of surveillance by means of regular colonoscopies.
Author: Liljegren, A|Lindgren, G|Brandberg, Y|Rotstein, S|Nilsson, B|Hatschek, T|Jaramillo, E|Lindblom, A
PMID: 15117997
Journal: Digestion. 2004;69(3):166-76. Epub 2004 Apr 28.
Title: Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: genetic reclassification and correlation with clinical features.
Author: Schiemann, U|Muller-Koch, Y|Gross, M|Daum, J|Lohse, P|Baretton, G|Muders, M|Mussack, T|Kopp, R|Holinski-Feder, E
PMID: 15118395
Journal: Am J Obstet Gynecol. 2004 Apr;190(4):935-42.
Title: RAS/RAF mutation and defective DNA mismatch repair in endometrial cancers.
Author: Mutch, David G|Powell, Matthew A|Mallon, Mary Ann|Goodfellow, Paul J
PMID: 15118616
Journal: Lab Invest. 2004 Jul;84(7):884-93.
Title: Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.
Author: Lee, Sun|Hwang, Kyu Sang|Lee, Hyeon Joo|Kim, Jung-Sun|Kang, Gyeong Hoon
PMID: 15122305
Journal: Cancer Res. 2004 May 1;64(9):3014-21.
Title: Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.
Author: Goel, Ajay|Arnold, Christian N|Niedzwiecki, Donna|Carethers, John M|Dowell, Jeannette M|Wasserman, Linda|Compton, Carolyn|Mayer, Robert J|Bertagnolli, Monica M|Boland, C Richard
PMID: 15126336
Journal: Pathologe. 2004 May;25(3):178-92.
Title: [Molecular pathology in hereditary colorectal cancer. Recommendations of the Collaborative German Study Group on hereditary colorectal cancer funded by the German Cancer Aid (Deutsche Krebshilfe)].
Author: Ruschoff, J|Roggendorf, B|Brasch, F|Mathiak, M|Aust, D E|Plaschke, J|Mueller, W|Poremba, C|Kloor, M|Keller, G|Muders, M|Blasenbreu-Vogt, S|Rummele, P|Muller, A|Buttner, R
PMID: 15138699
Journal: Anticancer Res. 2004 Mar-Apr;24(2B):649-54.
Title: The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer.
Author: Oyama, Kaeko|Kawakami, Kazuyuki|Maeda, Kazuya|Ishiguro, Kaname|Watanabe, Go
PMID: 15161007
Journal: Chin Med J (Engl). 2004 May;117(5):748-52.
Title: Clinical and genetic features of International Collaborative Group-hereditary nonpolyposis colorectal cancer families and suspected hereditary nonpolyposis colorectal cancer families.
Author: Yuan, Ying|Ye, Jun|Zheng, Shu
PMID: 15161546
Journal: Nat Genet. 2004 Jul;36(7):694-9. Epub 2004 Jun 6.
Title: The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer.
Author: Lipkin, Steven M|Rozek, Laura S|Rennert, Gad|Yang, Wei|Chen, Peng-Chieh|Hacia, Joseph|Hunt, Nathan|Shin, Brian|Fodor, Steve|Kokoris, Mark|Greenson, Joel K|Fearon, Eric|Lynch, Henry|Collins, Francis|Gruber, Stephen B
PMID: 15184898
Journal: Tumour Biol. 2004 Jan-Apr;25(1-2):62-8.
Title: Differential expression patterns of the insulin-like growth factor 2 gene in human colorectal cancer.
Author: Li, Shu-Rui|Ng, Chung Fai Jeremy|Banerjea, Ayan|Ahmed, Shafi|Hands, Rebecca|Powar, Michael|Ogunkolade, William|Dorudi, Sina|Bustin, Stephen A
PMID: 15192314
Journal: Cancer Lett. 2004 Jul 28;211(1):105-9.
Title: Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer.
Author: Miyaki, Michiko|Iijima, Takeru|Yamaguchi, Tatsuro|Kadofuku, Tsuyoki|Funata, Nobuaki|Mori, Takeo
PMID: 15194222
Journal: Eur J Cancer. 2004 Jul;40(10):1581-8.
Title: Abnormal Fhit protein expression and high frequency of microsatellite instability in sporadic colorectal cancer.
Author: Sarli, Leopoldo|Bottarelli, Lorena|Azzoni, Cinzia|Campanini, Nicoletta|Di Cola, Gabriella|Bader, Giovanni|Iusco, Domenico|Salvemini, Carlo|Caruso, Giuseppe|Donadei, Enrico|Pizzi, Silvia|D'Adda, Tiziana|Renato, Costi|Roncoroni, Luigi|Bordi, Cesare
PMID: 15196543
Journal: Zhonghua Yi Xue Za Zhi. 2004 May 2;84(9):714-7.
Title: [Clinical features and hMSH2/hMLH1 germline mutation screening of Chinese hereditary nonpolyposis colorectal cancer patients].
Author: Liu, Shan-run|Wang, Zhen-jun|Zhao, Bo|Wan, Yuan-lian|Huang, Yan-ting
PMID: 15200905
Journal: BMC Med Genet. 2004 Jun 24;5:16.
Title: HNPCC: six new pathogenic mutations.
Author: Kunstmann, Erdmute|Vieland, Judith|Brasch, Frank E|Hahn, Stephan A|Epplen, Joerg T|Schulmann, Karsten|Schmiegel, Wolff
PMID: 15217520
Journal: Cancer. 2004 Jul 1;101(1):172-7.
Title: Association of colonic and endometrial carcinomas in Portuguese families with hereditary nonpolyposis colorectal carcinoma significantly increases the probability of detecting a pathogenic mutation in mismatch repair genes, primarily the MSH2 gene.
Author: Lage, Pedro A|Albuquerque, Cristina|Sousa, Rita G|Cravo, Marilia L|Salazar, Maria|Francisco, Ines|Maia, Lara|Claro, Isabel|Suspiro, Alexandra|Rodrigues, Paula|Raposo, Helder|Fidalgo, Paulo A|Nobre-Leitao, Carlos
PMID: 15222003
Journal: Gastroenterology. 2004 Jul;127(1):17-25.
Title: Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
Author: Hendriks, Yvonne M C|Wagner, Anja|Morreau, Hans|Menko, Fred|Stormorken, Astrid|Quehenberger, Franz|Sandkuijl, Lodewijk|Moller, Pal|Genuardi, Maurizio|Van Houwelingen, Hans|Tops, Carli|Van Puijenbroek, Marjo|Verkuijlen, Paul|Kenter, Gemma|Van Mil, Anneke|M
PMID: 15236168
Journal: J Obstet Gynaecol Res. 2004 Aug;30(4):287-92.
Title: Two Japanese kindreds occurring endometrial cancer meeting new clinical criteria for hereditary non-polyposis colorectal cancer (HNPCC), Amsterdam Criteria II.
Author: Banno, Kouji|Susumu, Nobuyuki|Hirao, Takeshi|Yanokura, Megumi|Hirasawa, Akira|Aoki, Daisuke|Udagawa, Yasuhiro|Sugano, Kokichi|Nozawa, Shiro
PMID: 15238104
Journal: Bull Cancer. 2004 Apr;91(4):303-15.
Title: [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].
Author: Olschwang, Sylviane|Bonaiti, Catherine|Feingold, Josue|Frebourg, Thierry|Grandjouan, Sophie|Lasset, Christine|Laurent-Puig, Pierre|Lecuru, Fabrice|Millat, Bertrand|Sobol, Hagay|Thomas, Gilles|Eisinger, Francois
PMID: 15242312
Journal: Nucleic Acids Res. 2004 Jul 12;32(12):e100.
Title: Measurement of DNA mismatch repair activity in live cells.
Author: Lei, Xiufen|Zhu, Yong|Tomkinson, Alan|Sun, LuZhe
PMID: 15249596
Journal: Clin Genet. 2004 Aug;66(2):137-43.
Title: Putative common origin of two MLH1 mutations in Italian-Quebec hereditary non-polyposis colorectal cancer families.
Author: Thiffault, I|Foulkes, W D|Marcus, V A|Farber, D|Kasprzak, L|MacNamara, E|Wong, N|Hutter, P|Radice, P|Bertario, L|Chong, G
PMID: 15253764
Journal: Neoplasma. 2004;51(4):275-84.
Title: Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer.
Author: Plevova, P|Krepelova, A|Papezova, M|Sedlakova, E|Curik, R|Foretova, L|Navratilova, M|Novotny, J|Zapletalova, J|Palas, J|Nieslanik, J|Horacek, J|Dvorackova, J|Kolar, Z
PMID: 15254659
Journal: Cancer Res. 2004 Jul 15;64(14):4721-7.
Title: Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.
Author: Nakagawa, Hidewaki|Lockman, Janet C|Frankel, Wendy L|Hampel, Heather|Steenblock, Kelle|Burgart, Lawrence J|Thibodeau, Stephen N|de la Chapelle, Albert
PMID: 15256438
Journal: Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):65-73.
Title: Unravelling the genetics of prostate cancer.
Author: Edwards, Stephen M|Eeles, Rosalind A
PMID: 15264274
Journal: EMBO J. 2004 Aug 4;23(15):3164-74. Epub 2004 Jul 29.
Title: ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
Author: Fang, Yanan|Tsao, Cheng-Chung|Goodman, Barbara K|Furumai, Ryohei|Tirado, Carlos A|Abraham, Robert T|Wang, Xiao-Fan
PMID: 15282542
Journal: Oncol Rep. 2004 Sep;12(3):621-9.
Title: Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer.
Author: Caldes, Trinidad|Godino, Javier|Sanchez, Ana|Corbacho, Cesar|De la Hoya, Miguel|Lopez Asenjo, Jose|Saez, Carmen|Sanz, Julian|Benito, Manuel|Ramon Y Cajal, Santiago|Diaz-Rubio, Eduardo
PMID: 15289847
Journal: Hum Mol Genet. 2004 Oct 1;13(19):2303-11. Epub 2004 Aug 4.
Title: Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
Author: Oliveira, Carla|Westra, Jantine L|Arango, Diego|Ollikainen, Miina|Domingo, Enric|Ferreira, Ana|Velho, Sergia|Niessen, Renee|Lagerstedt, Kristina|Alhopuro, Pia|Laiho, Paivi|Veiga, Isabel|Teixeira, Manuel R|Ligtenberg, Marjolijn|Kleibeuker, Jan H|Sijmons, R
PMID: 15294875
Journal: Int J Cancer. 2004 Oct 10;111(6):921-8.
Title: Immunohistochemical patterns in rectal cancer: application of tissue microarray with prognostic correlations.
Author: Fernebro, Eva|Bendahl, Par-Ola|Dictor, Michael|Persson, Annette|Ferno, Marten|Nilbert, Mef
PMID: 15300804
Journal: World J Gastroenterol. 2004 Sep 15;10(18):2647-51.
Title: Clinical features and mismatch repair gene mutation screening in Chinese patients with hereditary nonpolyposis colorectal carcinoma.
Author: Liu, Shan-Run|Zhao, Bo|Wang, Zhen-Jun|Wan, Yuan-Lian|Huang, Yan-Ting
PMID: 15309712
Journal: Zhonghua Yi Xue Za Zhi. 2004 Jun 17;84(12):1014-7.
Title: [Effect of eukaryotic expression plasmid DNA methyltransferase gene on methylation status and transcription level of DNA mismatch repair genes in human colon cancer cell line].
Author: Lu, Rong|Fang, Jing-yuan|Zhu, Hong-yin|Chen, Ying-xuan|Cheng, Zhong-hua|Li, En-ling
PMID: 15312538
Journal: J Natl Cancer Inst. 2004 Aug 18;96(16):1204-7.
Title: Bias in intervention studies that enroll patients from high-risk clinics.
Author: Wacholder, Sholom
PMID: 15316055
Journal: Clin Genet. 2004 Sep;66(3):183-8.
Title: Family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hMSH2 or hMLH1.
Author: Ainsworth, P J|Koscinski, D|Fraser, B P|Stuart, J A
PMID: 15324316
Journal: Fam Cancer. 2004;3(2):85-91.
Title: Prognosis in DNA mismatch repair deficient colorectal cancer: are all MSI tumours equivalent?
Author: Clark, A J|Barnetson, R|Farrington, S M|Dunlop, M G
PMID: 15340258
Journal: Fam Cancer. 2004;3(2):93-100.
Title: HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences.
Author: Jass, Jeremy R
PMID: 15340259
Journal: Fam Cancer. 2004;3(2):101-7.
Title: Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Author: McGivern, A|Wynter, C V A|Whitehall, V L J|Kambara, T|Spring, K J|Walsh, M D|Barker, M A|Arnold, S|Simms, L A|Leggett, B A|Young, J|Jass, J R
PMID: 15340260
Journal: Fam Cancer. 2004;3(2):109-16.
Title: Evaluation of psychosocial effects of pre-symptomatic testing for breast/ovarian and colon cancer pre-disposing genes: a 12-month follow-up.
Author: Arver, Brita|Haegermark, Aina|Platten, Ulla|Lindblom, Annika|Brandberg, Yvonne
PMID: 15340261
Journal: Fam Cancer. 2004;3(2):123-7.
Title: A homozygous MSH6 mutation in a child with cafe-au-lait spots, oligodendroglioma and rectal cancer.
Author: Menko, Fred H|Kaspers, Gertjan L|Meijer, Gerrit A|Claes, Kathleen|van Hagen, Johanna M|Gille, Johan J P
PMID: 15340263
Journal: Fam Cancer. 2004;3(2):129-37.
Title: Genotyping possible polymorphic variants of human mismatch repair genes in healthy Korean individuals and sporadic colorectal cancer patients.
Author: Kim, Jin C|Roh, Seon A|Koo, Kum H|Ka, In H|Kim, Hee C|Yu, Chang S|Lee, Kang H|Kim, Jung S|Lee, Han I|Bodmer, Walter F
PMID: 15340264
Journal: Hum Genet. 2004 Oct;115(5):432-8. Epub 2004 Aug 31.
Title: A large MSH2 Alu insertion mutation causes HNPCC in a German kindred.
Author: Kloor, Matthias|Sutter, Christian|Wentzensen, Nicolas|Cremer, Friedrich W|Buckowitz, Annick|Keller, Monika|von Knebel Doeberitz, Magnus|Gebert, Johannes
PMID: 15340835
Journal: Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1495-501.
Title: Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer.
Author: Belshaw, Nigel J|Elliott, Giles O|Williams, Elizabeth A|Bradburn, David M|Mills, Sarah J|Mathers, John C|Johnson, Ian T
PMID: 15342451
Journal: J Med Genet. 2004 Sep;41(9):664-8.
Title: BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing.
Author: Domingo, E|Laiho, P|Ollikainen, M|Pinto, M|Wang, L|French, A J|Westra, J|Frebourg, T|Espin, E|Armengol, M|Hamelin, R|Yamamoto, H|Hofstra, R M W|Seruca, R|Lindblom, A|Peltomaki, P|Thibodeau, S N|Aaltonen, L A|Schwartz, S Jr
PMID: 15342696
Journal: Genet Test. 2004 Summer;8(2):157-62.
Title: Mutation analysis of hMSH2 and hMLH1 in colorectal cancer patients in India.
Author: Rajkumar, Thangarajan|Soumittra, Nagasamy|Pandey, Durgatosh|Nancy, Karunakaran Nirmala|Mahajan, Vikas|Majhi, Urmila
PMID: 15345113
Journal: Br J Cancer. 2004 Oct 4;91(7):1287-92.
Title: MSH6 missense mutations are often associated with no or low cancer susceptibility.
Author: Kariola, R|Hampel, H|Frankel, W L|Raevaara, T E|de la Chapelle, A|Nystrom-Lahti, M
PMID: 15354210
Journal: J Exp Clin Cancer Res. 2004 Jun;23(2):317-23.
Title: Repression of MLH1 and MGMT genes in colon mucosa adjacent to implanted cancer in athymic mouse.
Author: Kuniyasu, H|Sasaki, T|Sasahira, T|Chihara, Y|Ohmori, H
PMID: 15354418
Journal: Int J Gynecol Cancer. 2004 Sep-Oct;14(5):957-65.
Title: Molecular differences between RER+ and RER- sporadic endometrial carcinomas in a large population-based series.
Author: Macdonald, N D|Salvesen, H B|Ryan, A|Malatos, S|Stefansson, I|Iversen, O E|Akslen, L A|Das, S|Jacobs, I J
PMID: 15361209
Journal: Am J Clin Pathol. 2004 Sep;122(3):389-94.
Title: Defective mismatch-repair colorectal cancer: clinicopathologic characteristics and usefulness of immunohistochemical analysis for diagnosis.
Author: Jover, Rodrigo|Paya, Artemio|Alenda, Cristina|Poveda, Maria J|Peiro, Gloria|Aranda, F Ignacio|Perez-Mateo, Miguel
PMID: 15362369
Journal: Hum Mutat. 2004 Oct;24(4):351.
Title: Germline mutations in MLH1, MSH2 and MSH6 in Korean hereditary non-polyposis colorectal cancer families.
Author: Shin, Young-Kyoung|Heo, Seung-Chul|Shin, Joo-Ho|Hong, Sung-Hye|Ku, Ja-Lok|Yoo, Byong-Chul|Kim, Il-Jin|Park, Jae-Gahb
PMID: 15365995
Journal: Int J Cancer. 2004 Dec 10;112(5):846-53.
Title: Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.
Author: Bai, Alfa H C|Tong, Joanna H M|To, Ka-Fai|Chan, Michael W Y|Man, Ellen P S|Lo, Kwok-Wai|Lee, Janet F Y|Sung, Joseph J Y|Leung, Wai K
PMID: 15386372
Journal: Int J Cancer. 2004 Dec 10;112(5):754-9.
Title: Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers.
Author: Goel, Ajay|Arnold, Christian N|Tassone, Pierfrancesco|Chang, Dong K|Niedzwiecki, Donna|Dowell, Jeannette M|Wasserman, Linda|Compton, Carolyn|Mayer, Robert J|Bertagnolli, Monica M|Boland, C Richard
PMID: 15386381
Journal: Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6159-68.
Title: Characterization of mutator phenotype in familial colorectal cancer patients not fulfilling amsterdam criteria.
Author: Kim, Jin C|Lee, Kang H|Ka, In H|Koo, Kum H|Roh, Seon A|Kim, Hee C|Yu, Chang S|Kim, Tae W|Chang, Heung M|Gong, Gyeong Y|Kim, Jung S
PMID: 15448003
Journal: Jpn J Clin Oncol. 2004 Sep;34(9):556-60.
Title: The novel germline mutation of the hMLH1 gene in a case of suspected hereditary non-polyposis colorectal cancer (HNPCC) in a patient with no family history of cancer.
Author: Tomita, Naohiro|Fukunaga, Mutsumi|Okamura, Shu|Nakata, Ken|Ohzato, Hiroki|Tamura, Shigeyuki|Sugimoto, Keishi|Aihara, Tomohiko|Miki, Hirofumi|Takatsuka, Yuuichi|Matsuura, Nariaki|Ishikawa, Hideki|Iwanaga, Takeshi|Fukayama, Noriko|Sugano, Kokichi
PMID: 15466831
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Sep;33(5):395-8.
Title: [Hypermethylation of hMLH1 promoter in sporadic colorectal cancer].
Author: Song, Yong-mao|Yuan, Ying|Zheng, Shu
PMID: 15476320
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Sep;33(5):399-402.
Title: [Clinical features and mutation analysis of a poly-(A)8 tract in M3 cholinergic receptor gene in Chinese HNPCC families].
Author: Cao, Wen-ming|Yuan, Ying|Song, Yong-mao|Cai, Shan-rong|Zhang, Su-zhan
PMID: 15476321
Journal: Mol Cancer. 2004 Oct 11;3:28.
Title: A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.
Author: Lind, Guro E|Thorstensen, Lin|Lovig, Tone|Meling, Gunn I|Hamelin, Richard|Rognum, Torleiv O|Esteller, Manel|Lothe, Ragnhild A
PMID: 15476557
Journal: J Clin Oncol. 2004 Nov 15;22(22):4486-94. Epub 2004 Oct 13.
Title: Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
Author: Plaschke, Jens|Engel, Christoph|Kruger, Stefan|Holinski-Feder, Elke|Pagenstecher, Constanze|Mangold, Elisabeth|Moeslein, Gabriela|Schulmann, Karsten|Gebert, Johannes|von Knebel Doeberitz, Magnus|Ruschoff, Josef|Loeffler, Markus|Schackert, Hans K
PMID: 15483016
Journal: Exp Oncol. 2004 Sep;26(3):205-9.
Title: Genetic analysis of microsatellite markers in patients from hereditary nonpolyposis colorectal cancer (HNPCC) families.
Author: Smolarz, Beata|Romanowicz-Makowska, Hanna|Langner, Ewa|Kozlowska, Elzbieta|Kulig, Andrzej|Dziki, Adam
PMID: 15494688
Journal: Anticancer Res. 2004 Sep-Oct;24(5B):3161-7.
Title: Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy.
Author: Charara, Mona|Edmonston, Tina Bocker|Burkholder, Susan|Walters, Rhonda|Anne, Pramila|Mitchell, Edith|Fry, Robert|Boman, Bruce|Rose, Deborah|Fishel, Richard|Curran, Walter|Palazzo, Juan
PMID: 15510606
Journal: Fam Cancer. 2004;3(3-4):215-21.
Title: Genetic factors and colorectal cancer in Ashkenazi Jews.
Author: Locker, Gershon Y|Lynch, Henry T
PMID: 15516844
Journal: Fam Cancer. 2004;3(3-4):223-7.
Title: A636P testing in Ashkenazi Jews.
Author: Guillem, Jose G|Moore, Harvey G|Palmer, Crystal|Glogowski, Emily|Finch, Rob|Nafa, Khedoudja|Markowitz, Arnold J|Offit, Kenneth|Ellis, Nathan A
PMID: 15516845
Journal: Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15992-7. Epub 2004 Nov 1.
Title: Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.
Author: Fearnhead, Nicola S|Wilding, Jennifer L|Winney, Bruce|Tonks, Susan|Bartlett, Sylvia|Bicknell, David C|Tomlinson, Ian P M|Mortensen, Neil J McC|Bodmer, Walter F
PMID: 15520370
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Dis Markers. 2004;20(4-5):207-13.
Title: Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.
Author: Vasen, H F A|Hendriks, Y|de Jong, A E|van Puijenbroek, M|Tops, C|Brocker-Vriends, A H J T|Wijnen, J Th|Morreau, H
PMID: 15528786
Journal: Dis Markers. 2004;20(4-5):215-24.
Title: Role of the pathologist in the diagnosis of hereditary non-polyposis colorectal cancer.
Author: Jass, Jeremy R
PMID: 15528787
Journal: Dis Markers. 2004;20(4-5):237-50.
Title: Development of a fluorescent multiplex assay for detection of MSI-High tumors.
Author: Bacher, Jeffery W|Flanagan, Laura A|Smalley, Regenia L|Nassif, Nadine A|Burgart, Lawrence J|Halberg, Richard B|Megid, Wael M Abdel|Thibodeau, Stephen N
PMID: 15528789
Journal: Dis Markers. 2004;20(4-5):277-82.
Title: Diagnostic application of hMLH1 methylation in hereditary non-polyposis colorectal cancer.
Author: Matsubara, Nagahide
PMID: 15528793
Journal: Bratisl Lek Listy. 2004;105(5-6):215-24.
Title: Is there any role for prevention strategies for colorectal cancer other than population-based screening?
Author: Hlavaty, T|Lukac, L|Duris, I
PMID: 15535113
Journal: J Clin Oncol. 2004 Nov 15;22(22):4584-94.
Title: Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Author: Nagasaka, Takeshi|Sasamoto, Hiromi|Notohara, Kenji|Cullings, Harry M|Takeda, Masanori|Kimura, Keigo|Kambara, Takeshi|MacPhee, Donald G|Young, Joanne|Leggett, Barbara A|Jass, Jeremy R|Tanaka, Noriaki|Matsubara, Nagahide
PMID: 15542810
Journal: Clin Gastroenterol Hepatol. 2004 Nov;2(11):1017-25.
Title: Screening for defective DNA mismatch repair in stage II and III colorectal cancer patients.
Author: Chai, Siaw Ming|Zeps, Nik|Shearwood, Anne-Marie|Grieu, Fabienne|Charles, Adrian|Harvey, Jennet|Goldblatt, Jack|Joseph, David|Iacopetta, Barry
PMID: 15551255
Journal: Clin Colorectal Cancer. 2004 Nov;4(4):275-9.
Title: High-throughput gene sequencing assay development for hereditary nonpolyposis colon cancer.
Author: Huang, Donghui|Chen, Christina|Sun, Weimin|Strom, Charles M|Bender, Richard A
PMID: 15555211
Journal: Clin Cancer Res. 2004 Nov 15;10(22):7520-8.
Title: Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose.
Author: Seo, Yuji|Yan, Tao|Schupp, Jane E|Colussi, Valdir|Taylor, Kerri L|Kinsella, Timothy J
PMID: 15569982
Journal: Cancer Genet Cytogenet. 2004 Dec;155(2):149-51.
Title: Six novel heterozygous MLH1, MSH2, and MSH6 and one homozygous MLH1 germline mutations in hereditary nonpolyposis colorectal cancer.
Author: Rey, Jean-Marc|Noruzinia, Mehrdad|Brouillet, Jean-Paul|Sarda, Pierre|Maudelonde, Thierry|Pujol, Pascal
PMID: 15571801
Journal: Am J Surg Pathol. 2004 Dec;28(12):1553-9.
Title: What is the best way to assess microsatellite instability status in colorectal cancer? Study on a population base of 462 colorectal cancers.
Author: Chapusot, C|Martin, L|Puig, P Laurent|Ponnelle, T|Cheynel, N|Bouvier, A M|Rageot, D|Roignot, P|Rat, P|Faivre, J|Piard, F
PMID: 15577673
Journal: Arch Intern Med. 2004 Dec 13-27;164(22):2429-31.
Title: Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome).
Author: Watson, Patrice|Ashwathnarayan, Ramesh|Lynch, Henry T|Roy, Hemant K
PMID: 15596632
Journal: Jpn J Clin Oncol. 2004 Nov;34(11):660-6.
Title: Genetic characterization of Chinese hereditary non-polyposis colorectal cancer by DHPLC and multiplex PCR.
Author: Yuan, Ying|Huang, Yan-qing|Cai, Shan-rong|Song, Yong-mao|Zheng, Shu|Zhang, Su-zhan
PMID: 15613555
Journal: Rev Prat. 2004 Oct 31;54(16):1757-62.
Title: [Genetic predisposition and ovarian cancer].
Author: Coupier, Isabelle|Gauthier-Villars, Marion|This, Pascale|Stoppa-Lyonnet, Dominique
PMID: 15630879
Journal: Dis Colon Rectum. 2004 Dec;47(12):2086-91; discussion 2091-2.
Title: Prognostic implications of hMLH1 and p53 immunohistochemical status in right-sided colon cancer.
Author: Smyth, Edward F|Sharma, Abhiram|Sivarajasingham, Nala|Hartley, John|Monson, John R T|Cawkwell, Lynn
PMID: 15657659
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Nov;25(11):978-81.
Title: [Study on the relationship between genetic polymorphism Val384Asp in hMLH1 gene and the risk of four different carcinomas].
Author: Zhang, Xiao-Mei|Li, Jin-Tian|Zhu, Ming|Wu, Xiao-Liu|Gao, Ping|Zhou, Ping|Wang, Ya-Ping
PMID: 15769334
Journal: Sarcoma. 2004;8(4):123-7.
Title: Immunohistochemical Loss of the DNA Mismatch Repair Proteins MSH2 and MSH6 in Malignant Fibrous Histiocytomas.
Author: Ericson, Kajsa|Engellau, Jacob|Persson, Annette|Lindblom, Annika|Domanski, Henryk|Akerman, Mans|Nilbert, Mef
PMID: 18521406
Journal: Cancer Res Treat. 2004 Dec;36(6):360-6.
Title: Responsiveness of CPT-11 in respect to hMLH1 and hMSH2 protein expression in the primary colorectal cancer.
Author: Park, In Ja|Kim, Hee Cheol|Yu, Chang Sik|Chang, Heung Moon|Lee, Jea Hwan|Kim, Jong Hoon|Kim, Tae Won|Kim, Jung Sun|Kim, Jin Cheon
PMID: 20368829
Journal: Mod Pathol. 2005 Feb;18(2):170-8.
Title: Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author: Dong, Seung M|Lee, Eui J|Jeon, Eun S|Park, Cheol K|Kim, Kyoung-Mee
PMID: 15389252
Journal: Mod Pathol. 2005 Feb;18(2):244-9.
Title: Signet ring cell carcinoma of the colorectum: correlations between microsatellite instability, clinicopathologic features and survival.
Author: Kakar, Sanjay|Smyrk, Thomas C
PMID: 15492759
Journal: Hum Mol Genet. 2005 Jan 15;14(2):235-9. Epub 2004 Nov 24.
Title: Low levels of microsatellite instability characterize MLH1 and MSH2 HNPCC carriers before tumor diagnosis.
Author: Alazzouzi, Hafid|Domingo, Enric|Gonzalez, Sara|Blanco, Ignacio|Armengol, Manel|Espin, Eloi|Plaja, Alberto|Schwartz, Simo|Capella, Gabriel|Schwartz, Simo Jr
PMID: 15563510
Journal: Oncogene. 2005 Jan 20;24(4):706-13.
Title: Restoring mismatch repair does not stop the formation of reciprocal translocations in the colon cancer cell line HCA7 but further destabilizes chromosome number.
Author: Abdel-Rahman, Wael M|Lohi, Hannes|Knuutila, Sakari|Peltomaki, Paivi
PMID: 15580308
Journal: Oncol Rep. 2005 Jan;13(1):11-6.
Title: Microsatellite instability and expression of mismatch repair genes in sporadic endometrial cancer coexisting with colorectal or breast cancer.
Author: Takano, Katsumi|Ichikawa, Yoshihito|Ueno, Ei|Ohwada, Michitaka|Suzuki, Mitsuaki|Tsunoda, Hajime|Miwa, Masanao|Uchida, Kazuhiko|Yoshikawa, Hiroyuki
PMID: 15583795
Journal: Int J Mol Med. 2005 Jan;15(1):85-90.
Title: The profile of hMLH1 methylation and microsatellite instability in colorectal and non-small cell lung cancer.
Author: Okuda, Toshiyuki|Kawakami, Kazuyuki|Ishiguro, Kaname|Oda, Makoto|Omura, Kenji|Watanabe, Go
PMID: 15583832
Journal: Gut. 2005 Jan;54(1):169.
Title: An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome.
Author: Olschwang, S|Laurent-Puig, P|Eisinger, F|Millat, B
PMID: 15591525
Journal: Cancer. 2005 Jan 15;103(2):229-36.
Title: Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors.
Author: Kidd, Mark|Eick, Geeta|Shapiro, Michael D|Camp, Robert L|Mane, Shrikant M|Modlin, Irvin M
PMID: 15599934
Journal: J Biol Chem. 2005 Feb 18;280(7):5516-26. Epub 2004 Dec 14.
Title: DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.
Author: Meyers, Mark|Wagner, Mark W|Mazurek, Anthony|Schmutte, Christoph|Fishel, Richard|Boothman, David A
PMID: 15611052
Journal: Am J Surg Pathol. 2005 Jan;29(1):96-104.
Title: Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms.
Author: Shia, Jinru|Klimstra, David S|Nafa, Khedoudja|Offit, Kenneth|Guillem, Jose G|Markowitz, Arnold J|Gerald, William L|Ellis, Nathan A
PMID: 15613860
Journal: Oncol Rep. 2005 Feb;13(2):325-8.
Title: Development and application of a multiplex PCR procedure for the detection of DNA methylation in colorectal cancer.
Author: Anacleto, Charles|Rossi, Benedito|Lopes, Ademar|Soares, Fernando A|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria A|Simpson, Andrew J G|Pena, Sergio D J
PMID: 15643519
Journal: Annu Rev Med. 2005;56:539-54.
Title: Inherited susceptibility to colorectal cancer.
Author: Rowley, Peter T
PMID: 15660526
Journal: World J Gastroenterol. 2005 Feb 14;11(6):778-84.
Title: Loss of heterozygosity: an independent prognostic factor of colorectal cancer.
Author: Chang, Shih-Ching|Lin, Jen-Kou|Lin, Tzu-Chen|Liang, Wen-Yih
PMID: 15682467
Journal: Int J Cancer. 2005 Jul 10;115(5):673-7.
Title: Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma.
Author: Aust, Daniela E|Haase, Michael|Dobryden, Lyudmyla|Markwarth, Annett|Lohrs, Udo|Wittekind, Christian|Baretton, Gustavo B|Tannapfel, Andrea
PMID: 15704157
Journal: Clin Cancer Res. 2005 Feb 1;11(3):1203-9.
Title: Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps.
Author: Petko, Zsolt|Ghiassi, Mahan|Shuber, Anthony|Gorham, Janice|Smalley, Walter|Washington, M Kay|Schultenover, Stephen|Gautam, Shiva|Markowitz, Sanford D|Grady, William M
PMID: 15709190
Journal: Hum Pathol. 2005 Jan;36(1):101-11.
Title: Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon.
Author: Oh, Kirstine|Redston, Mark|Odze, Robert D
PMID: 15712188
Journal: JAMA. 2005 Feb 16;293(7):799-809.
Title: Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.
Author: Casey, Graham|Lindor, Noralane M|Papadopoulos, Nickolas|Thibodeau, Stephen N|Moskow, John|Steelman, Scott|Buzin, Carolyn H|Sommer, Steve S|Collins, Christine E|Butz, Malinda|Aronson, Melyssa|Gallinger, Steven|Barker, Melissa A|Young, Joanne P|Jass, Jeremy
PMID: 15713769
Journal: Eur J Gastroenterol Hepatol. 2005 Mar;17(3):317-22.
Title: Critical issues in the identification and management of patients with hereditary non-polyposis colorectal cancer.
Author: Lackner, C|Hoefler, G
PMID: 15716656
Journal: Ann R Coll Surg Engl. 2005 Jan;87(1):15-20.
Title: Epigenetics, mismatch repair genes and colorectal cancer.
Author: Wheeler, J M D
PMID: 15720901
Journal: Korean J Gastroenterol. 2005 Feb;45(2):78-87.
Title: [Hereditary colorectal cancer].
Author: Park, Jae-Gahb|Kim, Il-Jin
PMID: 15725711
Journal: Virchows Arch. 2005 Feb;446(2):112-9. Epub 2004 Dec 10.
Title: Expression of the hMLH1 and hMSH2 proteins in normal tissues: relationship to cancer predisposition in hereditary non-polyposis colon cancer.
Author: Plevova, Pavlina|Sedlakova, Eva|Zapletalova, Jana|Krepelova, Anna|Skypalova, Petra|Kolar, Zdenek
PMID: 15735976
Journal: Cancer Lett. 2005 Mar 18;220(1):85-93.
Title: Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors.
Author: Takahashi, Tomonori|Min, Zhenghua|Uchida, Iichiro|Arita, Michitsune|Watanabe, Yoh|Koi, Minoru|Hemmi, Hiromichi
PMID: 15737691
Journal: Eur J Med Res. 2005 Jan 28;10(1):23-8.
Title: Detection of occult high graded microsatellite instabilities in MMR gene mutation negative HNPCC tumors by addition of complementary marker analysis.
Author: Schiemann, U|Muller-Koch, Y|Gross, M|Glas, J|Baretton, G|Muders, M|Mussack, T|Holinski-Feder, E
PMID: 15737950
Journal: Dig Dis Sci. 2005 Feb;50(2):336-44.
Title: Hereditary nonpolyposis colorectal cancer (Lynch syndrome): criteria for identification and management.
Author: Kouraklis, Gregory|Misiakos, Evangelos P
PMID: 15745097
Journal: J Gastrointest Surg. 2005 Mar;9(3):329-35.
Title: The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer.
Author: Velayos, Fernando S|Lee, Suk-Hwan|Qiu, Hongming|Dykes, Sharon|Yiu, Raymond|Terdiman, Jonathan P|Garcia-Aguilar, Julio
PMID: 15749592
Journal: Carcinogenesis. 2005 Jun;26(6):1152-6. Epub 2005 Mar 10.
Title: CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.
Author: Brandes, Johann C|van Engeland, Manon|Wouters, Kim A D|Weijenberg, Matty P|Herman, James G
PMID: 15760919
Journal: Am J Surg Pathol. 2005 Apr;29(4):429-36.
Title: Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation.
Author: Chirieac, Lucian R|Shen, Lanlan|Catalano, Paul J|Issa, Jean-Pierre|Hamilton, Stanley R
PMID: 15767794
Journal: Br J Cancer. 2005 Mar 28;92(6):1137-43.
Title: Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency.
Author: Din, F V N|Stark, L A|Dunlop, M G
PMID: 15770215
Journal: World J Gastroenterol. 2005 Mar 14;11(10):1481-8.
Title: Clinical phenotype and prevalence of hereditary nonpolyposis colorectal cancer syndrome in Chinese population.
Author: Zhang, Yuan-Zhi|Sheng, Jian-Qiu|Li, Shi-Rong|Zhang, Hong
PMID: 15770724
Journal: Hum Genet. 2005 May;116(6):461-5. Epub 2005 Mar 17.
Title: Evidence for genetic anticipation in hereditary non-polyposis colorectal cancer.
Author: Westphalen, Alexander A|Russell, Anna M|Buser, Mauro|Berthod, Claudine Rey|Hutter, Pierre|Plasilova, Martina|Mueller, Hansjakob|Heinimann, Karl
PMID: 15772852
Journal: Nucleic Acids Res. 2005 Mar 18;33(5):1628-36. Print 2005.
Title: Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.
Author: Oda, Shinya|Maehara, Yoshihiko|Ikeda, Yoichi|Oki, Eiji|Egashira, Akinori|Okamura, Yoshikazu|Takahashi, Ikuo|Kakeji, Yoshihiro|Sumiyoshi, Yasushi|Miyashita, Kaname|Yamada, Yu|Zhao, Yan|Hattori, Hiroyoshi|Taguchi, Ken-ichi|Ikeuchi, Tatsuro|Tsuzuki, Teruhisa
PMID: 15778432
Journal: Oncogene. 2005 Jun 2;24(24):3995-8.
Title: BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes.
Author: Domingo, Enric|Niessen, Renee C|Oliveira, Carla|Alhopuro, Pia|Moutinho, Catia|Espin, Eloi|Armengol, Manel|Sijmons, Rolf H|Kleibeuker, Jan H|Seruca, Raquel|Aaltonen, Lauri A|Imai, Kohzoh|Yamamoto, Hiroyuki|Schwartz, Simo Jr|Hofstra, Robert M W
PMID: 15782118
Journal: World J Gastroenterol. 2005 Mar 21;11(11):1673-9.
Title: Clinicopathological and molecular genetic analysis of HNPCC in China.
Author: Luo, Ding-Cun|Cai, Qi|Sun, Meng-Hong|Ni, Yao-Zhong|Ni, Shi-Chang|Chen, Zhe-Jing|Li, Xiao-Yang|Tao, Chong-Wei|Zhang, Xue-Miao|Shi, Da-Ren
PMID: 15786548
Journal: Clin Cancer Res. 2005 Mar 15;11(6):2180-7.
Title: Microsatellite instability testing in colorectal carcinoma: choice of markers affects sensitivity of detection of mismatch repair-deficient tumors.
Author: Hatch, Stephanie B|Lightfoot, Harry M Jr|Garwacki, Christopher P|Moore, Dominic T|Calvo, Benjamin F|Woosley, John T|Sciarrotta, Janiece|Funkhouser, William K|Farber, Rosann A
PMID: 15788665
Journal: J Med Genet. 2005 Apr;42(4):e22.
Title: No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer.
Author: Vahteristo, P|Ojala, S|Tamminen, A|Tommiska, J|Sammalkorpi, H|Kiuru-Kuhlefelt, S|Eerola, H|Aaltonen, L A|Aittomaki, K|Nevanlinna, H
PMID: 15805151
Journal: Oncogene. 2005 May 19;24(22):3657-68.
Title: Modulation of CDK2-AP1 (p12(DOC-1)) expression in human colorectal cancer.
Author: Yuan, Ziquan|Gaba, Anu G|Kent, Tara Sotsky|Bennett, Anna|Miller, Agnes|Weber, Thomas K
PMID: 15806176
Journal: Hepatogastroenterology. 2005 Mar-Apr;52(62):450-4.
Title: Correlation between hMLH1/hMSH2 and p53 protein expression in sporadic colorectal cancer.
Author: Park, In J|Kim, Hee C|Kim, Jung S|Yu, Eun S|Yu, Chang S|Kim, Jin C
PMID: 15816455
Journal: Int J Cancer. 2005 Sep 10;116(4):495-9.
Title: Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.
Author: Yang, Kan|Fan, Kun-Hua|Lamprecht, Sergio A|Edelmann, Winfried|Kopelovich, Levy|Kucherlapati, Raju|Lipkin, Martin
PMID: 15818612
Journal: Biostatistics. 2005 Jul;6(3):450-64.
Title: Accuracy of MSI testing in predicting germline mutations of MSH2 and MLH1: a case study in Bayesian meta-analysis of diagnostic tests without a gold standard.
Author: Chen, Sining|Watson, Patrice|Parmigiani, Giovanni
PMID: 15831578
Journal: Gut. 2005 May;54(5):636-42.
Title: Association between family history and mismatch repair in colorectal cancer.
Author: Coggins, R P|Cawkwell, L|Bell, S M|Crockford, G P|Quirke, P|Finan, P J|Bishop, D T
PMID: 15831908
Journal: J Clin Oncol. 2005 Jul 20;23(21):4609-16. Epub 2005 Apr 18.
Title: Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome?
Author: Ollikainen, Miina|Abdel-Rahman, Wael M|Moisio, Anu-Liisa|Lindroos, Annette|Kariola, Reetta|Jarvela, Irma|Poyhonen, Minna|Butzow, Ralf|Peltomaki, Paivi
PMID: 15837969
Journal: Am J Epidemiol. 2005 May 1;161(9):806-15.
Title: Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphisms.
Author: Luchtenborg, Margreet|Weijenberg, Matty P|Kampman, Ellen|van Muijen, Goos N|Roemen, Guido M J M|Zeegers, Maurice P A|Goldbohm, R Alexandra|van 't Veer, Pieter|de Goeij, Anton F P M|van den Brandt, Piet A
PMID: 15840612
Journal: Am J Gastroenterol. 2005 May;100(5):1143-9.
Title: Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines.
Author: Velayos, Fernando S|Allen, Brian A|Conrad, Peggy G|Gum, James Jr|Kakar, Sanjay|Chung, Daniel C|Truta, Brindusa|Sleisenger, Marvin H|Kim, Young S|Terdiman, Jonathan P
PMID: 15842591
Journal: Am J Gastroenterol. 2005 May;100(5):1150-3.
Title: Adenomas in young patients: what is the optimal evaluation?
Author: Stoffel, Elena M|Syngal, Sapna
PMID: 15842592
Journal: Zhonghua Wai Ke Za Zhi. 2005 Mar 1;43(5):317-20.
Title: [Mutation detection of mismatch repair genes in hereditary nonpolyposis colorectal cancer by denaturing high-performance liquid chromatography].
Author: Huang, Yan-qin|Yuan, Ying|Wang, Ya-ping|Zhu, Ming|Zhang, Su-zhan|Zheng, Shu
PMID: 15842942
Journal: Gut. 2005 Aug;54(8):1146-50. Epub 2005 Apr 21.
Title: Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma.
Author: Durno, C|Aronson, M|Bapat, B|Cohen, Z|Gallinger, S
PMID: 15845562
Journal: Int J Cancer. 2005 Sep 20;116(5):692-702.
Title: Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
Author: Mangold, Elisabeth|Pagenstecher, Constanze|Friedl, Waltraut|Mathiak, Micaela|Buettner, Reinhard|Engel, Christoph|Loeffler, Markus|Holinski-Feder, Elke|Muller-Koch, Yvonne|Keller, Gisela|Schackert, Hans K|Kruger, Stefan|Goecke, Timm|Moeslein, Gabriela|Kloo
PMID: 15849733
Journal: JAMA. 2005 Apr 27;293(16):1986-94.
Title: Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.
Author: Pinol, Virginia|Castells, Antoni|Andreu, Montserrat|Castellvi-Bel, Sergi|Alenda, Cristina|Llor, Xavier|Xicola, Rosa M|Rodriguez-Moranta, Francisco|Paya, Artemio|Jover, Rodrigo|Bessa, Xavier
PMID: 15855432
Journal: Int J Cancer. 2005 Oct 10;116(6):914-9.
Title: Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans.
Author: Ashktorab, Hassan|Smoot, Duane T|Farzanmehr, Haleh|Fidelia-Lambert, Marie|Momen, Bahram|Hylind, Linda|Iacosozio-Dononue, Christine|Carethers, John M|Goel, Ajay|Boland, C Richard|Giardiello, Francis M
PMID: 15856472
Journal: J Clin Oncol. 2005 May 1;23(13):3074-8.
Title: TGFBR1*6A may contribute to hereditary colorectal cancer.
Author: Bian, Yansong|Caldes, Trinidad|Wijnen, Juul|Franken, Patrick|Vasen, Hans|Kaklamani, Virginia|Nafa, Khedoudja|Peterlongo, Paolo|Ellis, Nathan|Baron, John A|Burn, John|Moeslein, Gabriela|Morrison, Patrick J|Chen, Yu|Ahsan, Habibul|Watson, Patrice|Lynch, Hen
PMID: 15860866
Journal: Eur J Cancer. 2005 May;41(7):1058-64.
Title: Identification of predictive factors for the occurrence of predisposing MLH1 and MSH2 germline mutations among Sardinian patients with colorectal carcinoma.
Author: Colombino, Maria|Cossu, Antonio|Budroni, Mario|Satta, Maria P|Baldinu, Paola|Casula, Milena|Palomba, Grazia|Pisano, Marina|Sini, Maria C|Deiana, Angelo|Tanda, Francesco|Palmieri, Giuseppe
PMID: 15862756
Journal: Int J Oncol. 2005 Jun;26(6):1653-61.
Title: Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest.
Author: Sato, Ken|Kitajima, Yoshihiko|Kohya, Naohiko|Miyoshi, Atsushi|Koga, Yasuo|Miyazaki, Kohji
PMID: 15870882
Journal: N Engl J Med. 2005 May 5;352(18):1851-60.
Title: Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).
Author: Hampel, Heather|Frankel, Wendy L|Martin, Edward|Arnold, Mark|Khanduja, Karamjit|Kuebler, Philip|Nakagawa, Hidewaki|Sotamaa, Kaisa|Prior, Thomas W|Westman, Judith|Panescu, Jenny|Fix, Dan|Lockman, Janet|Comeras, Ilene|de la Chapelle, Albert
PMID: 15872200
Journal: Gastroenterology. 2005 May;128(5):1160-71.
Title: Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer.
Author: Truninger, Kaspar|Menigatti, Mirco|Luz, Judith|Russell, Anna|Haider, Ritva|Gebbers, Jan-Olaf|Bannwart, Fridolin|Yurtsever, Hueseyin|Neuweiler, Joerg|Riehle, Hans-Martin|Cattaruzza, Maria Sofia|Heinimann, Karl|Schar, Primo|Jiricny, Josef|Marra, Giancarlo
PMID: 15887099
Journal: Cancer Lett. 2005 Jun 8;223(2):285-91. Epub 2004 Nov 25.
Title: A novel missense germline mutation in exon 2 of the hMSH2 gene in a HNPCC family from Southern Italy.
Author: Baudi, Francesco|Fersini, Giuseppina|Lavecchia, Annamaria|Terracciano, Rosa|Leone, Francarlo|Quaresima, Barbara|Faniello, Maria C|De Paola, Loredana|Doldo, Patrizia|Cuda, Giovanni|Costanzo, Francesco|Venuta, Salvatore
PMID: 15896463
Journal: Magy Onkol. 2005;49(1):3-7. Epub 2005 May 18.
Title: [Activity of the National Oncology R&D Consortium in 2004].
Author: Timar, Jozsef
PMID: 15902326
Journal: Eur J Cancer. 2005 May;41(8):1195-202.
Title: Expression of tumour necrosis factor-related apoptosis-inducing ligand death receptors in sporadic and hereditary colorectal tumours: potential targets for apoptosis induction.
Author: Koornstra, Jan J|Jalving, Mathilde|Rijcken, Fleur E M|Westra, Jantine|Zwart, Nynke|Hollema, Harry|de Vries, Elisabeth G E|Hofstra, Robert W M|Plukker, John T M|de Jong, Steven|Kleibeuker, Jan H
PMID: 15911244
Journal: Wien Klin Wochenschr. 2005 Apr;117(7-8):269-77.
Title: Spectrum of germ-line MLH1 and MSH2 mutations in Austrian patients with hereditary nonpolyposis colorectal cancer.
Author: Wolf, Brigitte|Henglmueller, Silvia|Janschek, Elisabeth|Ilencikova, Denisa|Ludwig-Papst, Carmen|Bergmann, Michael|Mannhalter, Christine|Wrba, Friedrich|Karner-Hanusch, Judith
PMID: 15926618
Journal: Clin Cancer Res. 2005 Jun 1;11(11):4234-40.
Title: High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
Author: Ricciardiello, Luigi|Ceccarelli, Claudio|Angiolini, Graziella|Pariali, Milena|Chieco, Pasquale|Paterini, Paola|Biasco, Guido|Martinelli, Giuseppe N|Roda, Enrico|Bazzoli, Franco
PMID: 15930362
Journal: Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title: Molecular markers that predict response to colon cancer therapy.
Author: Ahmed, Farid E
PMID: 15934813
Journal: J Med Genet. 2005 Jun;42(6):491-6.
Title: Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment.
Author: Quehenberger, F|Vasen, H F A|van Houwelingen, H C
PMID: 15937084
Journal: Genes Chromosomes Cancer. 2005 Oct;44(2):123-38.
Title: Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
Author: van der Klift, Heleen|Wijnen, Juul|Wagner, Anja|Verkuilen, Paul|Tops, Carli|Otway, Robyn|Kohonen-Corish, Maija|Vasen, Hans|Oliani, Cristina|Barana, Daniela|Moller, Pal|Delozier-Blanchet, Celia|Hutter, Pierre|Foulkes, William|Lynch, Henry|Burn, John|Moslei
PMID: 15942939
Journal: Genet Test. 2005 Summer;9(2):147-51.
Title: Germline mutations in the MYH gene in Swedish familial and sporadic colorectal cancer.
Author: Zhou, X-L|Djureinovic, T|Werelius, B|Lindmark, G|Sun, X-F|Lindblom, A
PMID: 15943555
Journal: Orv Hetil. 2005 May 15;146(20):1009-16.
Title: [The first molecular analysis of a Hungarian HNPCC family: a novel MSH2 germline mutation].
Author: Czako, Laszlo|Tiszlavicz, Laszlo|Takacs, Robert|Baradnay, Gellert|Lonovics, Janos|Cserni, Gabor|Zavodna, Katarina|Bartosova, Zdena
PMID: 15945244
Journal: Cancer Genet Cytogenet. 2005 Jul 1;160(1):61-7.
Title: Large genomic aberrations in MSH2 and MLH1 genes are frequent in Chinese colorectal cancer.
Author: Zhu, Ming|Li, Jintian|Zhang, Xiaomei|Liu, Xiaorong|Friedl, Waltraut|Zhang, Yuanying|Wu, Xiaoliu|Propping, Peter|Wang, Yaping
PMID: 15949572
Journal: Fam Cancer. 2005;4(2):183-6.
Title: The CHEK2 1100delC allele is not relevant for risk assessment in HNPCC and HBCC Spanish families.
Author: Sanchez de Abajo, Ana|de la Hoya, Miguel|Godino, Javier|Furio, Vicente|Tosar, Alicia|Perez-Segura, Pedro|Diaz-Rubio, Eduardo|Caldes, Trinidad
PMID: 15951971
Journal: Clin Genet. 2005 Jul;68(1):80-7.
Title: Frequency of hereditary non-polyposis colorectal cancer among Uruguayan patients with colorectal cancer.
Author: Sarroca, C|Valle, A Della|Fresco, R|Renkonen, E|Peltomaki, P|Lynch, Ht
PMID: 15952990
Journal: Gut. 2005 Dec;54(12):1733-40. Epub 2005 Jun 14.
Title: Hereditary non-polyposis colorectal cancer: clinical and molecular evidence for a new entity of hereditary colorectal cancer.
Author: Mueller-Koch, Y|Vogelsang, H|Kopp, R|Lohse, P|Keller, G|Aust, D|Muders, M|Gross, M|Daum, J|Schiemann, U|Grabowski, M|Scholz, M|Kerker, B|Becker, I|Henke, G|Holinski-Feder, E
PMID: 15955785
Journal: Anal Bioanal Chem. 2005 Aug;382(7):1702-7. Epub 2005 Jun 16.
Title: One-milliliter wet-digestion for inductively coupled plasma mass spectrometry (ICP-MS): determination of platinum-DNA adducts in cells treated with platinum(II) complexes.
Author: Yamada, Kanae|Kato, Naoyuki|Takagi, Akimitsu|Koi, Minoru|Hemmi, Hiromichi
PMID: 15959768
Journal: Clinics (Sao Paulo). 2005 Jun;60(3):251-6.
Title: Hereditary nonpolyposis colorectal cancer identification and surveillance of high-risk families.
Author: Silva, Roberta Vasconcelos E|Garicochea, Bernardo|Cotti, Guilherme|Maranho, Isabel Cristina|Cutait, Raul
PMID: 15962087
Journal: Neoplasia. 2005 Apr;7(4):331-5.
Title: Colorectal cancer "methylator phenotype": fact or artifact?
Author: Anacleto, Charles|Leopoldino, Andreia M|Rossi, Benedito|Soares, Fernando A|Lopes, Ademar|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria A|Simpson, Andrew J G|Pena, Sergio D J
PMID: 15967110
Journal: Dis Colon Rectum. 2005 Sep;48(9):1723-7.
Title: Low allele frequency of MLH1 D132H in American colorectal and endometrial cancer patients.
Author: Shin, Brian Y|Chen, Huiping|Rozek, Laura S|Paxton, Leslie|Peel, David J|Anton-Culver, Hoda|Rennert, Gad|Mutch, David G|Goodfellow, Paul J|Gruber, Stephen B|Lipkin, Steve M
PMID: 15991064
Journal: Cancer Genet Cytogenet. 2005 Jul 15;160(2):164-8.
Title: Hereditary breast cancer syndromes in a Turkish population. Results of molecular germline analysis.
Author: Guran, Sefik|Ozet, Ahmet|Dede, Murat|Gille, Johan J P|Yenen, Mufit Cemal
PMID: 15993273
Journal: Clin Genet. 2005 Aug;68(2):137-45.
Title: Clinical and molecular characteristics of hereditary non-polyposis colorectal cancer families in Southeast Asia.
Author: Lee, S-C|Guo, J-Y|Lim, R|Soo, R|Koay, E|Salto-Tellez, M|Leong, A|Goh, B-C
PMID: 15996210
Journal: Clin Cancer Res. 2005 Jul 1;11(13):4689-93.
Title: A homozygous mutation in MSH6 causes Turcot syndrome.
Author: Hegde, Madhuri R|Chong, Belinda|Blazo, Maria E|Chin, Lip Hon E|Ward, Patricia A|Chintagumpala, Murali M|Kim, John Y|Plon, Sharon E|Richards, C Sue
PMID: 16000562
Journal: Z Gastroenterol. 2005 Jul;43(7):647-51.
Title: [Evaluation of outpatient management in HNPCC].
Author: Bach, K|Huppe, D|Schmiegel, W|Epplen, J T|Kunstmann, E
PMID: 16001346
Journal: Cancer Lett. 2005 Jul 8;225(1):93-8.
Title: Genomic rearrangements in MSH2 and MLH1 are rare mutational events in Spanish patients with hereditary nonpolyposis colorectal cancer.
Author: Castellvi-Bel, Sergi|Castells, Antoni|Strunk, Mark|Ferrandez, Angel|Piazuelo, Elena|Mila, Montserrat|Pinol, Virginia|Rodriguez-Moranta, Francisco|Andreu, Montserrat|Lanas, Angel|Pique, Josep Maria
PMID: 16003840
Journal: Oncogene. 2005 Nov 17;24(51):7630-4.
Title: Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
Author: Oliveira, Carla|Velho, Sergia|Domingo, Enric|Preto, Ana|Hofstra, Robert M W|Hamelin, Richard|Yamamoto, Hiroyuki|Seruca, Raquel|Schwartz, Simo Jr
PMID: 16007118
Journal: Acta Gastroenterol Belg. 2005 Apr-Jun;68(2):241-2.
Title: Risk stratification for colorectal cancer and implications for screening.
Author: Tejpar, S
PMID: 16013642
Journal: Cancer. 2005 Sep 1;104(5):952-61.
Title: BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
Author: Lubomierski, Nikolaus|Plotz, Guido|Wormek, Marc|Engels, Knut|Kriener, Susanne|Trojan, Jorg|Jungling, Bernd|Zeuzem, Stefan|Raedle, Jochen
PMID: 16015629
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1619-25.
Title: Fruits, vegetables, and hMLH1 protein-deficient and -proficient colon cancer: The Netherlands cohort study.
Author: Wark, Petra A|Weijenberg, Matty P|van 't Veer, Pieter|van Wijhe, Gerda|Luchtenborg, Margreet|van Muijen, Goos N P|de Goeij, Anton F P M|Goldbohm, R Alexandra|van den Brandt, Piet A
PMID: 16030092
Journal: Carcinogenesis. 2005 Dec;26(12):2078-85. Epub 2005 Jul 20.
Title: Screening for genomic fragments that are methylated specifically in colorectal carcinoma with a methylated MLH1 promoter.
Author: Koinuma, Koji|Kaneda, Ruri|Toyota, Minoru|Yamashita, Yoshihiro|Takada, Shuji|Choi, Young Lim|Wada, Tomoaki|Okada, Masaki|Konishi, Fumio|Nagai, Hideo|Mano, Hiroyuki
PMID: 16033773
Journal: Biochem Soc Trans. 2005 Aug;33(Pt 4):689-93.
Title: Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition.
Author: Scherer, S J|Avdievich, E|Edelmann, W
PMID: 16042575
Journal: Biochem Soc Trans. 2005 Aug;33(Pt 4):718-20.
Title: Phenotype associated with recessively inherited mutations in DNA mismatch repair (MMR) genes.
Author: de Vos, M|Hayward, B|Bonthron, D T|Sheridan, E
PMID: 16042583
Journal: Biochem Soc Trans. 2005 Aug;33(Pt 4):728-9.
Title: DNA mismatch repair status may influence anti-neoplastic effects of butyrate.
Author: Coxhead, J M|Williams, E A|Mathers, J C
PMID: 16042586
Journal: Cancer Causes Control. 2005 Aug;16(6):749-53.
Title: ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States).
Author: Jones, J Shawn|Gu, Xiangjun|Lynch, Patrick M|Rodriguez-Bigas, Miguel|Amos, Christopher I|Frazier, Marsha L
PMID: 16049814
Journal: Lancet Oncol. 2005 Aug;6(8):566-72.
Title: Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.
Author: Kruger, Stefan|Silber, Ann-Sophie|Engel, Christoph|Gorgens, Heike|Mangold, Elisabeth|Pagenstecher, Constanze|Holinski-Feder, Elke|von Knebel Doeberitz, Magnus|Moeslein, Gabriela|Dietmaier, Wolfgang|Stemmler, Susanne|Friedl, Waltraut|Ruschoff, Josef|Schack
PMID: 16054567
Journal: J Cancer Res Clin Oncol. 2005 Nov;131(11):733-40. Epub 2005 Nov 1.
Title: Aberrant CpG island methylation in early-onset sporadic gastric carcinoma.
Author: Kim, Hee Cheol|Kim, Jin Cheon|Roh, Sun Ae|Yu, Chang Sik|Yook, Jeong Hwan|Oh, Sung Tae|Kim, Byung Sik|Park, Kun Choon|Chang, Rin
PMID: 16075282
Journal: Gastroenterology. 2005 Aug;129(2):537-49.
Title: Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
Author: Raevaara, Tiina E|Korhonen, Mari K|Lohi, Hannes|Hampel, Heather|Lynch, Elly|Lonnqvist, Karin E|Holinski-Feder, Elke|Sutter, Christian|McKinnon, Wendy|Duraisamy, Sekhar|Gerdes, Anne-Marie|Peltomaki, Paivi|Kohonen-Ccorish, Maija|Mangold, Elisabeth|Macrae, F
PMID: 16083711
Journal: Clin Genet. 2005 Sep;68(3):234-8.
Title: Novel genomic insertion-- deletion in MLH1: possible mechanistic role for non-homologous end-joining DNA repair.
Author: McVety, S|Younan, R|Li, L|Gordon, P H|Wong, N|Foulkes, W D|Chong, G
PMID: 16098012
Journal: Br J Cancer. 2005 Aug 22;93(4):472-7.
Title: The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers.
Author: Lawes, D A|Pearson, T|Sengupta, S|Boulos, P B
PMID: 16106253
Journal: J Clin Oncol. 2005 Sep 20;23(27):6524-32. Epub 2005 Aug 22.
Title: Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer.
Author: Southey, Melissa C|Jenkins, Mark A|Mead, Leeanne|Whitty, Jonathan|Trivett, Melanie|Tesoriero, Andrea A|Smith, Letitia D|Jennings, Kim|Grubb, Garry|Royce, Simon G|Walsh, Michael D|Barker, Melissa A|Young, Joanne P|Jass, Jeremy R|St John, D James B|Macrae,
PMID: 16116158
Journal: Cancer Detect Prev. 2005;29(4):356-60.
Title: Preoperative serum levels of the carcinoembryonic antigen in hereditary non-polyposis colorectal cancer compared to levels in sporadic colorectal cancer.
Author: Schiemann, Uwe|Gunther, Silke|Gross, Manfred|Henke, Gaby|Muller-Koch, Yvonne|Konig, August|Muders, Michael|Folwaczny, Christian|Mussack, Thomas|Holinski-Feder, Elke
PMID: 16122885
Journal: Nat Clin Pract Oncol. 2005 Aug;2(8):398-405.
Title: Serrated adenoma of the colorectum and the DNA-methylator phenotype.
Author: Jass, Jeremy R
PMID: 16130936
Journal: Fam Cancer. 2005;4(3):211-8.
Title: Evolution of the nomenclature for the hereditary colorectal cancer syndromes.
Author: Boland, C Richard
PMID: 16136380
Journal: Fam Cancer. 2005;4(3):249-54.
Title: Gynecologic Cancers in Lynch Syndrome/HNPCC.
Author: Lu, Karen H|Broaddus, Russell R
PMID: 16136386
Journal: Gastroenterol Clin Biol. 2005 Jun-Jul;29(6-7):667-75.
Title: Value of microsatellite instability typing in detecting hereditary non-polyposis colorectal cancer. A prospective multicentric study by the Association Aquitaine Gastro.
Author: Becouarn, Yves|Rullier, Anne|Gorry, Philippe|Smith, Denis|Richard-Molard, Bruno|Echinard, Emmanuel|Texereau, Patrick|Beyssac, Richard|Legoux, Jean-Louis|Lamouliatte, Herve|Frebourg, Thierry|Olschwang, Sylviane|Gilbert, Brigitte|Venat, Laurence|Picot, Vero
PMID: 16142001
Journal: BMC Cancer. 2005 Sep 5;5:112.
Title: Family history of colorectal cancer in Iran.
Author: Mahdavinia, Mahboobeh|Bishehsari, Faraz|Ansari, Reza|Norouzbeigi, Nasim|Khaleghinejad, Ahmad|Hormazdi, Mahshid|Rakhshani, Naser|Malekzadeh, Reza
PMID: 16143045
Journal: Gastroenterology. 2005 Sep;129(3):837-45.
Title: Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer.
Author: Samowitz, Wade S|Albertsen, Hans|Herrick, Jennifer|Levin, Theodore R|Sweeney, Carol|Murtaugh, Maureen A|Wolff, Roger K|Slattery, Martha L
PMID: 16143123
Journal: Cancer Genet Cytogenet. 2005 Oct 1;162(1):68-73.
Title: Who takes the lead in the development of ulcerative colitis-associated colorectal cancers: mutator, suppressor, or methylator pathway?
Author: Maia, Lara|Dinis, Joana|Cravo, Marilia|Claro, Isabel|Baltazar, Celia|Fonseca, Isabel|Veloso, Tavarela|Capelinha, Ana F|Carneiro, Fatima|Nobre-Leitao, Carlos
PMID: 16157203
Journal: Gut. 2005 Oct;54(10):1501-2.
Title: An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome.
Author: Vasen, H F A|de Vos Tot Nederveen Cappel, W H
PMID: 16162958
Journal: Clin Cancer Res. 2005 Sep 15;11(18):6466-71.
Title: Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation.
Author: Gill, Sharlene|Lindor, Noralane M|Burgart, Lawrence J|Smalley, Regenia|Leontovich, Olga|French, Amy J|Goldberg, Richard M|Sargent, Daniel J|Jass, Jeremy R|Hopper, John L|Jenkins, Mark A|Young, Joanne|Barker, Melissa A|Walsh, Michael D|Ruszkiewicz, Andrew
PMID: 16166421
Journal: J Pathol. 2005 Dec;207(4):377-84.
Title: Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified.
Author: Ward, Robyn Lynne|Turner, Jenny|Williams, Rachel|Pekarsky, Brita|Packham, Deborah|Velickovic, Marija|Meagher, Alan|O'Connor, Terence|Hawkins, Nicholas John
PMID: 16175654
Journal: J Pathol. 2005 Nov;207(3):285-94.
Title: Morphology and microsatellite instability in sporadic serrated and non-serrated colorectal cancer.
Author: Tuppurainen, Karoliina|Makinen, Johanna M|Junttila, Oili|Liakka, Annikki|Kyllonen, Atte P|Tuominen, Hannu|Karttunen, Tuomo J|Makinen, Markus J
PMID: 16177963
Journal: Am J Gastroenterol. 2005 Oct;100(10):2274-9.
Title: Quantitative detection of promoter hypermethylation in multiple genes in the serum of patients with colorectal cancer.
Author: Leung, Wai K|To, Ka-Fai|Man, Ellen P S|Chan, Michael W Y|Bai, Alfa H C|Hui, Aric J|Chan, Francis K L|Sung, Joseph J Y
PMID: 16181380
Journal: Am J Gastroenterol. 2005 Oct;100(10):2280-7.
Title: Molecular genetic alterations and clinical features in early-onset colorectal carcinomas and their role for the recognition of hereditary cancer syndromes.
Author: Losi, Lorena|Di Gregorio, Carmela|Pedroni, Monica|Ponti, Giovanni|Roncucci, Luca|Scarselli, Alessandra|Genuardi, Maurizio|Baglioni, Silvana|Marino, Massimiliano|Rossi, Giuseppina|Benatti, Piero|Maffei, Stefania|Menigatti, Mirco|Roncari, Barbara|Ponz de Le
PMID: 16181381
Journal: Cancer Causes Control. 2005 Nov;16(9):1041-54.
Title: Meat and fish consumption, APC gene mutations and hMLH1 expression in colon and rectal cancer: a prospective cohort study (The Netherlands).
Author: Luchtenborg, Margreet|Weijenberg, Matty P|de Goeij, Anton F P M|Wark, Petra A|Brink, Mirian|Roemen, Guido M J M|Lentjes, Marjolein H F M|de Bruine, Adriaan P|Goldbohm, R Alexandra|van 't Veer, Pieter|van den Brandt, Piet A
PMID: 16184469
Journal: J Med Genet. 2005 Oct;42(10):766-8.
Title: The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.
Author: Sun, S|Greenwood, C M T|Thiffault, I|Hamel, N|Chong, G|Foulkes, W D
PMID: 16199548
Journal: J Med Genet. 2005 Oct;42(10):769-73.
Title: The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC).
Author: Kruger, S|Bier, A|Engel, C|Mangold, E|Pagenstecher, C|von Knebel Doeberitz, M|Holinski-Feder, E|Moeslein, G|Schulmann, K|Plaschke, J|Ruschoff, J|Schackert, H K
PMID: 16199549
Journal: BMC Cancer. 2005 Oct 3;5:126.
Title: Numbers of mutations to different types of colorectal cancer.
Author: Calabrese, Peter|Mecklin, Jukka-Pekka|Jarvinen, Heikki J|Aaltonen, Lauri A|Tavare, Simon|Shibata, Darryl
PMID: 16202134
Journal: Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6853-61.
Title: High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes.
Author: Woods, Michael O|Hyde, Angela J|Curtis, Fiona K|Stuckless, Susan|Green, Jane S|Pollett, Aaron F|Robb, J Desmond|Green, Roger C|Croitoru, Marina E|Careen, Amanda|Chaulk, Jason A W|Jegathesan, Jegan|McLaughlin, John R|Gallinger, Steven S|Younghusband, H Ban
PMID: 16203774
Journal: Cancer Res. 2005 Oct 1;65(19):8662-70.
Title: Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
Author: Chen, Peng-Chieh|Dudley, Sandra|Hagen, Wayne|Dizon, Diana|Paxton, Leslie|Reichow, Denise|Yoon, Song-Ro|Yang, Kan|Arnheim, Norman|Liskay, R Michael|Lipkin, Steven M
PMID: 16204034
Journal: Clin Cancer Res. 2005 Oct 15;11(20):7304-10.
Title: Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway.
Author: Llor, Xavier|Pons, Elisenda|Xicola, Rosa M|Castells, Antoni|Alenda, Cristina|Pinol, Virginia|Andreu, Montserrat|Castellvi-Bel, Sergi|Paya, Artemio|Jover, Rodrigo|Bessa, Xavier|Giros, Anna|Roca, Anna|Gassull, Miquel A
PMID: 16243801
Journal: Arch Pathol Lab Med. 2005 Nov;129(11):1385-9.
Title: Testing for defective DNA mismatch repair in colorectal carcinoma: a practical guide.
Author: Burgart, Lawrence J
PMID: 16253016
Journal: Arch Pathol Lab Med. 2005 Nov;129(11):1390-7.
Title: Performance of the revised Bethesda guidelines for identification of colorectal carcinomas with a high level of microsatellite instability.
Author: Gologan, Adrian|Krasinskas, Alyssa|Hunt, Jennifer|Thull, Darcy L|Farkas, Linda|Sepulveda, Antonia R
PMID: 16253017
Journal: Gynecol Obstet Fertil. 2005 Nov;33(11):851-6. Epub 2005 Oct 26.
Title: [Hereditary predispositions to gynaecological cancers].
Author: Coupier, I|Pujol, P
PMID: 16256400
Journal: Ugeskr Laeger. 2005 Oct 31;167(44):4159-63.
Title: [Hereditary colorectal cancer].
Author: Bernstein, Inge T|Bulow, Steffen
PMID: 16266567
Journal: Ugeskr Laeger. 2005 Oct 31;167(44):4189-91.
Title: [Follow-up of patients after curative surgery for colorectal cancer].
Author: Wille-Jorgensen, Peer A|Madsen, Mogens Rorbaek
PMID: 16266577
Journal: Acta Gastroenterol Belg. 2005 Jul-Sep;68(3):294-301.
Title: Microsatellite instability in sporadic and inherited colon adenocarcinomas from Greek patients: correlation with several clinicopathological characteristics.
Author: Michalopoulos, N V|Saetta, A A|Lazaris, A C|Gigelou, F|Koilakou, S|Patsouris, E
PMID: 16268414
Journal: World J Gastroenterol. 2005 Oct 7;11(37):5770-6.
Title: Low prevalence of germline hMSH6 mutations in colorectal cancer families from Spain.
Author: Sanchez de Abajo, Ana|de la Hoya, Miguel|Tosar, Alicia|Godino, Javier|Fernandez, Juan-Manuel|Asenjo, Jose-Lopez|Villamil, Beatriz-Perez|Segura, Pedro-Perez|Diaz-Rubio, Eduardo|Caldes, Trinidad
PMID: 16270383
Journal: Biomedica. 2005 Sep;25(3):315-24.
Title: [Detection mutations in the DNA mismatch repair genes of hMLH1 and hMSH2 genes in Colombian families with suspicion of hereditary non-polyposis colorectal carcinoma (Lynch syndrome)].
Author: Gomez, Andrea|Salguero, Gustavo|Garcia, Herbert|Aristizabal, Fabio|Gutierrez, Oscar|Angel, Luis Alberto|Padron, Jorge|Martinez, Carlos|Martinez, Humberto|Malaver, Omar|Barvo, Rosa|Giraldo, Alejandro
PMID: 16276679
Journal: Clin Genet. 2005 Dec;68(6):533-41.
Title: Two Swedish founder MSH6 mutations, one nonsense and one missense, conferring high cumulative risk of Lynch syndrome.
Author: Cederquist, K|Emanuelsson, M|Wiklund, F|Golovleva, I|Palmqvist, R|Gronberg, H
PMID: 16283884
Journal: Chirurg. 2005 Dec;76(12):1135-44.
Title: [Prophylactic surgery for hereditary non-polyposis colorectal cancer].
Author: Moslein, G|Ohmann, C|Wenzel, M
PMID: 16292564
Journal: Oncology. 2005;69(4):354-62.
Title: Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer.
Author: Noda, Hiroshi|Kato, Yo|Yoshikawa, Hirohide|Arai, Masami|Togashi, Kazutomo|Nagai, Hideo|Konishi, Fumio|Miki, Yoshio
PMID: 16293975
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4021-8.
Title: The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
Author: Sato, Ken|Kitajima, Yoshihiko|Koga, Yasuo|Miyazaki, Kohji
PMID: 16309194
Journal: Cancer Res. 2005 Dec 1;65(23):10759-66.
Title: Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.
Author: Cannavo, Elda|Marra, Giancarlo|Sabates-Bellver, Jacob|Menigatti, Mirco|Lipkin, Steven M|Fischer, Franziska|Cejka, Petr|Jiricny, Josef
PMID: 16322221
Journal: Zhonghua Yi Xue Za Zhi. 2005 Nov 9;85(42):2995-3000.
Title: [Hereditary predisposition of colorectal cancer and prevalence of hereditary nonpolyposis colorectal cancer in general population of colorectal cancer patients in China].
Author: Zhang, Yuan-zhi|Sheng, Jian-qiu|Li, Shi-rong|Wu, Zi-tao
PMID: 16324388
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Dec;22(6):603-6.
Title: The analysis for identifying large DNA fragment aberrations of MSH2 and MLH1 genes from familial colorectal cancer in China.
Author: Zhu, Ming|Liu, Xiao-rong|Huang, Yan-qin|Yuan, Ying|Li, Jin-tian|Zhang, Xiao-mei|Zhang, Yuan-ying|Wang, Ya-ping
PMID: 16331552
Journal: J Gastroenterol Hepatol. 2005 Dec;20(12):1920-6.
Title: CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.
Author: Kim, Hee Cheol|Roh, Sun Ae|Ga, In Hwa|Kim, Jung-Sun|Yu, Chang Sik|Kim, Jin Cheon
PMID: 16336454
Journal: Fam Cancer. 2005;4(4):291-4.
Title: Mutational analysis of hMsh6 in Israeli HNPCC and HNPCC-like families.
Author: Dovrat, Shiri|Figer, Arie|Fidder, Herma H|Neophytou, Pavlos|Fireman, Zvi|Geva, Ravit|Zidan, Jamal|Flex, Dov|Meir, Shimon Bar|Friedman, Eitan
PMID: 16341805
Journal: Fam Cancer. 2005;4(4):295-300.
Title: Long term follow-up of HNPCC gene mutation carriers: compliance with screening and satisfaction with counseling and screening procedures.
Author: Wagner, Anja|van Kessel, Ingrid|Kriege, Mieke G|Tops, Carli M J|Wijnen, Juul Th|Vasen, Hans F A|van der Meer, Conny A|van Oostrom, Iris I H|Meijers-Heijboer, Hanne
PMID: 16341806
Journal: Fam Cancer. 2005;4(4):301-5.
Title: Survival of patients with ovarian cancer due to a mismatch repair defect.
Author: Crijnen, Th E M|Janssen-Heijnen, M L G|Gelderblom, H|Morreau, J|Nooij, M A|Kenter, G G|Vasen, H F A
PMID: 16341807
Journal: Fam Cancer. 2005;4(4):323-33.
Title: Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations.
Author: Bandipalliam, Prathap
PMID: 16341812
Journal: BMC Cancer. 2005 Dec 15;5:160.
Title: Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.
Author: Luchtenborg, Margreet|Weijenberg, Matty P|Wark, Petra A|Saritas, A Merdan|Roemen, Guido M J M|van Muijen, Goos N P|de Bruine, Adriaan P|van den Brandt, Piet A|de Goeij, Anton F P M
PMID: 16356174
Journal: Dis Colon Rectum. 2005 Nov;48(11):2061-9.
Title: Mechanisms of microsatellite instability in colorectal cancer patients in different age groups.
Author: Yiu, Raymond|Qiu, Hongming|Lee, Suk-Hwan|Garcia-Aguilar, Julio
PMID: 16374936
Journal: Genet Test. 2005 Winter;9(4):313-9.
Title: Impact of genetic counseling and DNA testing on individuals with colorectal cancer with a positive family history: a population-based study.
Author: Loader, Starlene|Shields, Cleveland|Rowley, Peter T
PMID: 16379545
Journal: Rev Med Suisse. 2005 Nov 30;1(43):2791-7.
Title: [Hereditary non polyposis colon cancer--basic principle and ethical considerations].
Author: Bouzourene, Hanifa|Monnerat, Christian
PMID: 16396368
Journal: World J Gastroenterol. 2005 Nov 14;11(42):6620-3.
Title: Detection of germline mutations of hMLH1 and hMSH2 based on cDNA sequencing in China.
Author: Wang, Chao-Fu|Zhou, Xiao-Yan|Zhang, Tai-Ming|Sun, Meng-Hong|Shi, Da-Ren
PMID: 16425354
Journal: World J Gastroenterol. 2005 Dec 21;11(47):7541-4.
Title: Is colonoscopy sufficient for colorectal cancer surveillance in all HNPCC patients?
Author: Corleto, Vito D|Zykaj, Ermira|Mercantini, Paolo|Pilozzi, Emanuela|Rossi, Michele|Carnuccio, Antonella|Di Giulio, Emilio|Ziparo, Vincenzo|Delle Fave, Gianfranco
PMID: 16437731
Journal: Conf Proc IEEE Eng Med Biol Soc. 2005;3:2417-20.
Title: A comparison of multi-layer neural network and logistic regression in hereditary non-polyposis colorectal cancer risk assessment.
Author: Kokuer, Munevver|G Naguib, Raouf|Jancovic, Peter|Banfield Younghusband, H|Green, Roger
PMID: 17282725
Journal: Hered Cancer Clin Pract. 2005 Nov 15;3(1):43-7.
Title: Deletion Mutations in an Australian Series of HNPCC Patients.
Author: McPhillips, Mary|Meldrum, Cliff J|Creegan, Rhona|Edkins, Edward|Scott, Rodney J
PMID: 20223028
Journal: Hered Cancer Clin Pract. 2005 May 15;3(2):81-4.
Title: Case report: familial gastric cancer and chordoma in the same family.
Author: Weber, Walter|Scott, Rodney J
PMID: 20223035
Journal: Hered Cancer Clin Pract. 2005 Nov 15;3(4):155-64.
Title: Hereditary colorectal cancer in china.
Author: Shu, Zheng|Yanqin, Huang|Ying, Yuan
PMID: 20223042
Journal: Hered Cancer Clin Pract. 2005 Nov 15;3(4):165-70.
Title: Organization and running of the first comprehensive hereditary cancer clinic in India.
Author: Rajkumar, T|Soumittra, N|Vidubala, E|Sridevi, V|Mahajan, V|Ramanan, Sg|Vijaya, S
PMID: 20223043
Journal: Mod Pathol. 2006 Jan;19(1):59-68.
Title: Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author: Ogino, Shuji|Brahmandam, Mohan|Cantor, Mami|Namgyal, Chungdak|Kawasaki, Takako|Kirkner, Gregory|Meyerhardt, Jeffrey A|Loda, Massimo|Fuchs, Charles S
PMID: 16118624
Journal: Int J Cancer. 2006 Feb 15;118(4):907-15.
Title: DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.
Author: Wynter, Coral V A|Kambara, Takeshi|Walsh, Michael D|Leggett, Barbara A|Young, Joanne|Jass, Jeremy R
PMID: 16152625
Journal: Oncogene. 2006 Jan 5;25(1):139-46.
Title: Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability.
Author: Koinuma, K|Yamashita, Y|Liu, W|Hatanaka, H|Kurashina, K|Wada, T|Takada, S|Kaneda, R|Choi, Y L|Fujiwara, S-I|Miyakura, Y|Nagai, H|Mano, H
PMID: 16247484
Journal: Gut. 2006 Jun;55(6):848-55.
Title: Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer.
Author: Jover, R|Zapater, P|Castells, A|Llor, X|Andreu, M|Cubiella, J|Pinol, V|Xicola, R M|Bujanda, L|Rene, J M|Clofent, J|Bessa, X|Morillas, J D|Nicolas-Perez, D|Paya, A|Alenda, C
PMID: 16299036
Journal: Cancer. 2006 Jan 1;106(1):87-94.
Title: Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma.
Author: Broaddus, Russell R|Lynch, Henry T|Chen, Lee-May|Daniels, Molly S|Conrad, Peggy|Munsell, Mark F|White, Kristin G|Luthra, Rajyalakshmi|Lu, Karen H
PMID: 16323174
Journal: Cancer Lett. 2006 Sep 8;241(1):150-7. Epub 2005 Dec 6.
Title: N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).
Author: Pistorius, Steffen|Gorgens, Heike|Kruger, Stefan|Engel, Christoph|Mangold, Elisabeth|Pagenstecher, Constanze|Holinski-Feder, Elke|Moeslein, Gabriela|von Knebel Doeberitz, Magnus|Ruschoff, Josef|Karner-Hanusch, Judith|Saeger, Hans-Detlev|Schackert, Hans K
PMID: 16337339
Journal: Cancer Lett. 2006 Jan 8;231(1):129-37.
Title: Expression of sFRP-4 and beta-catenin in human colorectal carcinoma.
Author: Feng Han, Qian|Zhao, Wenying|Bentel, Jacky|Shearwood, Anne-Marie|Zeps, Nik|Joseph, David|Iacopetta, Barry|Dharmarajan, Arun
PMID: 16356838
Journal: Biomed Chromatogr. 2006 Aug;20(8):815-20.
Title: Methylation analysis of hMLH1 gene promoter by a bisulfite-sensitive single-strand conformation polymorphism-capillary electrophoresis method.
Author: Shi, Xianzhe|Li, Jianhua|Zhao, Chunxia|Lv, Shen|Xu, Guowang
PMID: 16358356
Journal: Am J Med Genet A. 2006 Feb 1;140(3):195-9.
Title: A novel MSH2 germline mutation in homozygous state in two brothers with colorectal cancers diagnosed at the age of 11 and 12 years.
Author: Muller, Annegret|Schackert, Hans K|Lange, Bettina|Ruschoff, Josef|Fuzesi, Laslow|Willert, Joerg|Burfeind, Peter|Shah, Parantu|Becker, Heinz|Epplen, Joerg Thomas|Stemmler, Susanne
PMID: 16372347
Journal: Gut. 2006 Jul;55(7):1000-6. Epub 2006 Jan 11.
Title: CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Author: Ogino, S|Cantor, M|Kawasaki, T|Brahmandam, M|Kirkner, G J|Weisenberger, D J|Campan, M|Laird, P W|Loda, M|Fuchs, C S
PMID: 16407376
Journal: Eur J Hum Genet. 2006 May;14(5):561-6.
Title: Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor.
Author: Plaschke, Jens|Linnebacher, Michael|Kloor, Matthias|Gebert, Johannes|Cremer, Friedrich W|Tinschert, Sigrid|Aust, Daniela E|von Knebel Doeberitz, Magnus|Schackert, Hans K
PMID: 16418736
Journal: Br J Cancer. 2006 Feb 27;94(4):593-8.
Title: DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer.
Author: Kawakami, K|Ruszkiewicz, A|Bennett, G|Moore, J|Grieu, F|Watanabe, G|Iacopetta, B
PMID: 16421593
Journal: Cancer Res. 2006 Jan 15;66(2):659-64.
Title: Gene conversion is a frequent mechanism of inactivation of the wild-type allele in cancers from MLH1/MSH2 deletion carriers.
Author: Zhang, Jian|Lindroos, Annette|Ollila, Saara|Russell, Anna|Marra, Giancarlo|Mueller, Hansjakob|Peltomaki, Paivi|Plasilova, Martina|Heinimann, Karl
PMID: 16423994
Journal: BMC Med Genet. 2006 Jan 20;7:5.
Title: Microsatellite instability analysis in hereditary non-polyposis colon cancer using the Bethesda consensus panel of microsatellite markers in the absence of proband normal tissue.
Author: Chialina, Sergio G|Fornes, Claudia|Landi, Carolina|de la Vega Elena, Carlos D|Nicolorich, Maria V|Dourisboure, Ricardo J|Solano, Angela|Solis, Edita A
PMID: 16426447
Journal: Cancer Lett. 2006 Dec 8;244(2):195-202. Epub 2006 Jan 19.
Title: Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance.
Author: Gibson, Shannon L|Narayanan, Latha|Hegan, Denise Campisi|Buermeyer, Andrew B|Liskay, R Michael|Glazer, Peter M
PMID: 16426742
Journal: Hum Pathol. 2006 Feb;37(2):185-9.
Title: Mismatch repair genes in renal cortical neoplasms.
Author: Baiyee, Daniel|Banner, Barbara
PMID: 16426918
Journal: Crit Rev Oncol Hematol. 2006 Jun;58(3):208-20. Epub 2006 Jan 23.
Title: The genetics of HNPCC: application to diagnosis and screening.
Author: Abdel-Rahman, Wael M|Mecklin, Jukka-Pekka|Peltomaki, Paivi
PMID: 16434208
Journal: J Mol Diagn. 2006 Feb;8(1):68-75.
Title: Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer.
Author: Fox, Edward J|Leahy, Dermot T|Geraghty, Robert|Mulcahy, Hugh E|Fennelly, David|Hyland, John M|O'Donoghue, Diarmuid P|Sheahan, Kieran
PMID: 16436636
Journal: Clin Genet. 2006 Jan;69(1):40-7.
Title: Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study).
Author: Kurzawski, G|Suchy, J|Lener, M|Klujszo-Grabowska, E|Kladny, J|Safranow, K|Jakubowska, K|Jakubowska, A|Huzarski, T|Byrski, T|Debniak, T|Cybulski, C|Gronwald, J|Oszurek, O|Oszutowska, D|Kowalska, E|Gozdz, S|Niepsuj, S|Slomski, R|Plawski, A|Lacka-Wojciechows
PMID: 16451135
Journal: Acta Oncol. 2006;45(1):61-6.
Title: Mismatch repair, p53 and chromosomal aberrations in primary colorectal carcinomas.
Author: Mehigan, Brian J|Ashman, James N E|Baker, Richard P|Macdonald, Alastair|Greenman, John|Monson, John R T|Cawkwell, Lynn
PMID: 16464797
Journal: Gastroenterology. 2006 Feb;130(2):312-22.
Title: Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome).
Author: Hendriks, Yvonne M C|Jagmohan-Changur, Shantie|van der Klift, Heleen M|Morreau, Hans|van Puijenbroek, Marjo|Tops, Carli|van Os, Theo|Wagner, Anja|Ausems, Margreet G F M|Gomez, Encarna|Breuning, Martijn H|Brocker-Vriends, Annette H J T|Vasen, Hans F A|Wijn
PMID: 16472587
Journal: Cancer Lett. 2006 Feb 20;233(1):124-30.
Title: Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1.
Author: Fang, Jing Yuan|Lu, Rong|Mikovits, Judy A|Cheng, Zhong Hua|Zhu, Hong Yin|Chen, Ying Xuan
PMID: 16473673
Journal: Gynecol Oncol. 2006 Aug;102(2):189-94. Epub 2006 Feb 14.
Title: Occult endometrial cancer and decision making for prophylactic hysterectomy in hereditary nonpolyposis colorectal cancer patients.
Author: Pistorius, Steffen|Kruger, Stefan|Hohl, Ruth|Plaschke, Jens|Distler, Wolfgang|Saeger, Hans-Detlev|Schackert, Hans Konrad
PMID: 16476474
Journal: Eur J Clin Invest. 2006 Mar;36(3):188-92.
Title: Low colonic glutathione detoxification capacity in patients at risk for colon cancer.
Author: Grubben, M J A L|van den Braak, C C M|Nagengast, F M|Peters, W H M
PMID: 16506964
Journal: J Natl Cancer Inst. 2006 Mar 1;98(5):358-61.
Title: PMS2 mutations in childhood cancer.
Author: De Vos, Michel|Hayward, Bruce E|Charlton, Ruth|Taylor, Graham R|Glaser, Adam W|Picton, Susan|Cole, Trevor R|Maher, Eamonn R|McKeown, Carole M E|Mann, Jill R|Yates, John R|Baralle, Diana|Rankin, Julia|Bonthron, David T|Sheridan, Eamonn
PMID: 16507833
Journal: World J Gastroenterol. 2006 Feb 7;12(5):809-11.
Title: First report of a de novo germline mutation in the MLH1 gene.
Author: Stulp, Rein P|Vos, Yvonne J|Mol, Bart|Karrenbeld, Arend|de Raad, Monique|van der Mijle, Huub J C|Sijmons, Rolf H
PMID: 16521201
Journal: Int J Colorectal Dis. 2006 Dec;21(8):847-50. Epub 2006 Mar 9.
Title: Polyposis and early cancer in a patient with low penetrant mutations in MSH6 and APC: hereditary colorectal cancer as a polygenic trait.
Author: Okkels, Henrik|Sunde, Lone|Lindorff-Larsen, Karen|Thorlacius-Ussing, Ole|Gandrup, Per|Lindebjerg, Jan|Stubbeteglbjaerg, Peter|Oestergaard, John R|Nielsen, Finn Cilius|Krarup, Henrik Bygum
PMID: 16525781
Journal: Fam Cancer. 2006;5(1):21-8.
Title: The value of multi-modal gene screening in HNPCC in Quebec: three mutations in mismatch repair genes that would have not been correctly identified by genomic DNA sequencing alone.
Author: McVety, Susan|Li, Lili|Thiffault, Isabelle|Gordon, Philip H|Macnamara, Elizabeth|Wong, Nora|Australie, Karlene|Kasprzak, Lidia|Chong, George|Foulkes, William D
PMID: 16528605
Journal: Diagn Mol Pathol. 2006 Mar;15(1):17-23.
Title: Hypermethylation of the MLH1 promoter with concomitant absence of transcript and protein occurs in small patches of crypt cells in unaffected mucosa from sporadic colorectal carcinoma.
Author: Nuovo, Gerard J|Nakagawa, Hidewaki|Sotamaa, Kaisa|Chapelle, Albert de la
PMID: 16531764
Journal: Clin Cancer Res. 2006 Mar 1;12(5):1494-500.
Title: Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer.
Author: Grabsch, Heike|Dattani, Mit|Barker, Lisa|Maughan, Nicola|Maude, Karen|Hansen, Olaf|Gabbert, Helmut E|Quirke, Phil|Mueller, Wolfram
PMID: 16533773
Journal: World J Gastroenterol. 2006 Feb 28;12(8):1192-7.
Title: Pedigree and genetic analysis of a novel mutation carrier patient suffering from hereditary nonpolyposis colorectal cancer.
Author: Tanyi, Miklos|Olasz, Judith|Lukacs, Geza|Csuka, Orsolya|Toth, Laszlo|Szentirmay, Zoltan|Ress, Zsuzsa|Barta, Zsolt|Tanyi, Janos L|Damjanovich, Laszlo
PMID: 16534870
Journal: Appl Immunohistochem Mol Morphol. 2006 Mar;14(1):42-5.
Title: Immunohistochemical mismatch repair proteins expression in colorectal cancer.
Author: Valentini, Anna Maria|Armentano, Raffaele|Pirrelli, Michele|Gentile, Mattia|Caruso, Maria Lucia
PMID: 16540729
Journal: Appl Immunohistochem Mol Morphol. 2006 Mar;14(1):115-21.
Title: Optimization of antibodies for detection of the mismatch repair proteins MLH1, MSH2, MSH6, and PMS2 using a biotin-free visualization system.
Author: Hansen, Tine Plato|Nielsen, Ole|Fenger, Claus
PMID: 16540742
Journal: Clin Genet. 2006 Mar;69(3):254-62.
Title: A genetic model for determining MSH2 and MLH1 carrier probabilities based on family history and tumor microsatellite instability.
Author: Marroni, F|Pastrello, C|Benatti, P|Torrini, M|Barana, D|Cordisco, E L|Viel, A|Mareni, C|Oliani, C|Genuardi, M|Bailey-Wilson, J E|Ponz de Leon, M|Presciuttini, S
PMID: 16542391
Journal: Clin Genet. 2006 Mar;69(3):290-3.
Title: HMLH1 and HMSH2 germline mutations in Greek families with hereditary non-polyposis colorectal cancer.
Author: Kataki, A|Gomatos, I P|Arapis, K|Mparatsis, S|Alepas, P|Kaintatzis, A|Nikolopoulou, M|Leandros, E|Konstadoulakis, M M|Bramis, J
PMID: 16542397
Journal: Clin Cancer Res. 2006 Mar 15;12(6):1686-92.
Title: Cyclooxygenase 2 expression in colorectal cancer with DNA mismatch repair deficiency.
Author: Castells, Antoni|Paya, Artemio|Alenda, Cristina|Rodriguez-Moranta, Francisco|Agrelo, Ruben|Andreu, Montserrat|Pinol, Virginia|Castellvi-Bel, Sergi|Jover, Rodrigo|Llor, Xavier|Pons, Elisenda|Elizalde, J Ignasi|Bessa, Xavier|Alcedo, Javier|Salo, Joan|Medina
PMID: 16551850
Journal: Int J Cancer. 2006 Aug 15;119(4):801-6.
Title: RAB32 hypermethylation and microsatellite instability in gastric and endometrial adenocarcinomas.
Author: Shibata, David|Mori, Yuriko|Cai, Kun|Zhang, Li|Yin, Jing|Elahi, Abul|Hamelin, Richard|Wong, Yick F|Lo, Wing K|Chung, Tony K H|Sato, Fumiaki|Karpeh, Martin S Jr|Meltzer, Stephen J
PMID: 16557577
Journal: Orv Hetil. 2006 Feb 26;147(8):363-8.
Title: [Current concepts in the genetics of hereditary and sporadic colorectal cancer and the role of genetics in patient management. Hereditary colorectal cancers].
Author: Lakatos, Peter Laszlo|Lakatos, Laszlo
PMID: 16579336
Journal: Cancer Res. 2006 Apr 1;66(7):3541-9.
Title: Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Author: McGarvey, Kelly M|Fahrner, Jill A|Greene, Eriko|Martens, Joost|Jenuwein, Thomas|Baylin, Stephen B
PMID: 16585178
Journal: J Hum Genet. 2006;51(5):391-6. Epub 2006 Apr 5.
Title: Cancer genetics: colorectal cancer as a model.
Author: Bodmer, Walter F
PMID: 16596323
Journal: Community Genet. 2006;9(2):98-106.
Title: Economic evaluation of the familial cancer programme in Western Australia: predictive genetic testing for familial adenomatous polyposis and hereditary non-polyposis colorectal carcinoma.
Author: Breheny, N|Geelhoed, E|Goldblatt, J|Ee, H|O'Leary, P
PMID: 16612060
Journal: Clin Gastroenterol Hepatol. 2006 Apr;4(4):489-98.
Title: Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family study.
Author: Jenkins, Mark A|Baglietto, Laura|Dowty, James G|Van Vliet, Christine M|Smith, Letitia|Mead, Leeanne J|Macrae, Finlay A|St John, D James B|Jass, Jeremy R|Giles, Graham G|Hopper, John L|Southey, Melissa C
PMID: 16616355
Journal: Int J Exp Pathol. 2006 Apr;87(2):89-99.
Title: Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC.
Author: Tokairin, Yutaka|Kakinuma, Shizuko|Arai, Masami|Nishimura, Mayumi|Okamoto, Mieko|Ito, Eisaku|Akashi, Makoto|Miki, Yoshio|Kawano, Tatsuyuki|Iwai, Takehisa|Shimada, Yoshiya
PMID: 16623753
Journal: Gut. 2006 Dec;55(12):1781-8. Epub 2006 Apr 24.
Title: Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancer.
Author: Niessen, R C|Berends, M J W|Wu, Y|Sijmons, R H|Hollema, H|Ligtenberg, M J L|de Walle, H E K|de Vries, E G E|Karrenbeld, A|Buys, C H C M|van der Zee, A G J|Hofstra, R M W|Kleibeuker, J H
PMID: 16636019
Journal: J Mol Diagn. 2006 May;8(2):209-17.
Title: Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
Author: Ogino, Shuji|Kawasaki, Takako|Brahmandam, Mohan|Cantor, Mami|Kirkner, Gregory J|Spiegelman, Donna|Makrigiorgos, G Mike|Weisenberger, Daniel J|Laird, Peter W|Loda, Massimo|Fuchs, Charles S
PMID: 16645207
Journal: Clin Cancer Res. 2006 May 1;12(9):2738-44.
Title: Thymidylate synthase expression in colon carcinomas with microsatellite instability.
Author: Sinicrope, Frank A|Rego, Rafaela L|Halling, Kevin C|Foster, Nathan R|Sargent, Daniel J|La Plant, Betsy|French, Amy J|Allegra, Carmen J|Laurie, John A|Goldberg, Richard M|Witzig, Thomas E|Thibodeau, Stephen N
PMID: 16675565
Journal: Pathol Biol (Paris). 2006 May;54(4):215-29.
Title: [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].
Author: Olschwang, S|Bonaiti-Pellie, C|Feingold, J|Frebourg, T|Grandjouan, S|Lasset, C|Laurent-Puig, P|Lecuru, F|Millat, B|Sobol, H|Thomas, G|Eisinger, F
PMID: 16677780
Journal: Colorectal Dis. 2006 Jun;8(5):411-7.
Title: Immunohistochemistry detects mismatch repair gene defects in colorectal cancer.
Author: Hameed, F|Goldberg, P A|Hall, P|Algar, U|van Wijk, R|Ramesar, R
PMID: 16684085
Journal: Am J Clin Pathol. 2006 Jun;125(6):823-31.
Title: A cost-effective algorithm for hereditary nonpolyposis colorectal cancer detection.
Author: Bouzourene, Hanifa|Taminelli, Lorenzo|Chaubert, Pascal|Monnerat, Christian|Seelentag, Walter|Sandmeier, Dominique|Andrejevic, Snejana|Matter, Maurice|Bosman, Fred|Benhattar, Jean
PMID: 16690480
Journal: J Pathol. 2006 Jul;209(3):328-35.
Title: Birt-Hogg-Dube gene mutations in human endometrial carcinomas with microsatellite instability.
Author: Fujii, H|Jiang, W|Matsumoto, T|Miyai, K|Sashara, K|Ohtsuji, N|Hino, O
PMID: 16691634
Journal: Am J Gastroenterol. 2006 May;101(5):1104-11.
Title: Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations.
Author: Rodriguez-Moranta, Francisco|Castells, Antoni|Andreu, Montserrat|Pinol, Virginia|Castellvi-Bel, Sergi|Alenda, Cristina|Llor, Xavier|Xicola, Rosa M|Jover, Rodrigo|Paya, Artemio|Bessa, Xavier|Balaguer, Francesc|Cubiella, Joaquin|Arguello, Lidia|Morillas, Ju
PMID: 16696788
Journal: Mod Pathol. 2006 Aug;19(8):1083-90.
Title: Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Author: Ogino, Shuji|Brahmandam, Mohan|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 16699497
Journal: Genes Chromosomes Cancer. 2006 Aug;45(8):781-9.
Title: CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer.
Author: Kim, Young-Ho|Petko, Zsolt|Dzieciatkowski, Slavomir|Lin, Li|Ghiassi, Mahan|Stain, Steve|Chapman, William C|Washington, Mary Kay|Willis, Joseph|Markowitz, Sanford D|Grady, William M
PMID: 16708352
Journal: J Clin Oncol. 2006 May 20;24(15):2359-67.
Title: Immunohistochemical test for MLH1 and MSH2 expression predicts clinical outcome in stage II and III colorectal cancer patients.
Author: Lanza, Giovanni|Gafa, Roberta|Santini, Alessandra|Maestri, Iva|Guerzoni, Laura|Cavazzini, Luigi
PMID: 16710035
Journal: Ann Thorac Surg. 2006 Jun;81(6):2008-13.
Title: Prognostic factors and analysis of microsatellite instability in resected pulmonary metastases from colorectal carcinoma.
Author: Melloni, Giulio|Doglioni, Claudio|Bandiera, Alessandro|Carretta, Angelo|Ciriaco, Paola|Arrigoni, Gianluigi|Zannini, Piero
PMID: 16731121
Journal: Fam Cancer. 2006;5(2):179-89.
Title: Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients.
Author: Spaepen, M|Vankeirsbilck, B|Van Opstal, S|Tejpar, S|Van Cutsem, E|Geboes, K|Legius, E|Matthijs, G
PMID: 16736289
Journal: Fam Cancer. 2006;5(2):195-9.
Title: A 'nonsense' mutation leads to aberrant splicing of hMLH1 in a German hereditary non-polyposis colorectal cancer family.
Author: Baehring, J|Sutter, C|Kadmon, M|Doeberitz, M V Knebel|Gebert, J
PMID: 16736291
Journal: Cancer Genet Cytogenet. 2006 Jun;167(2):138-44.
Title: RIS1, a gene with trinucleotide repeats, is a target in the mutator pathway of colorectal carcinogenesis.
Author: Iglesias, Daniel|Fernandez-Peralta, Antonia M|Nejda, Nargisse|Daimiel, Lidia|Azcoita, Mariano Moreno|Oliart, Soledad|Gonzalez-Aguilera, Juan J
PMID: 16737913
Journal: Anticancer Res. 2006 Jan-Feb;26(1B):533-7.
Title: Predominance of younger age, advanced stage, poorly-differentiated and mucinous histology in Israeli Arab patients with colorectal cancer.
Author: Shpitz, Baruch|Millman, Maya|Ziv, Yehiel|Klein, Ehud|Grankin, Milla|Gochberg, Semion|Sandbank, Judith|Halevi, Arie|Bernheim, Joelle|Khromov, Yakov|Gutman, Mordechay|Sayfan, Joel
PMID: 16739315
Journal: Anal Biochem. 2006 Aug 1;355(1):117-24.
Title: Microarray-based molecular margin methylation pattern analysis in colorectal carcinoma.
Author: Zhang, Dingdong|Bai, Yunfei|Ge, Qinyu|Qiao, Yingjuan|Wang, Yan|Chen, Zaozao|Lu, Zuhong
PMID: 16756932
Journal: Ann Oncol. 2006 Jun;17 Suppl 7:vii91-6.
Title: Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin.
Author: Bishehsari, F|Mahdavinia, M|Malekzadeh, R|Verginelli, F|Catalano, T|Sotoudeh, M|Bazan, V|Agnese, V|Esposito, D L|De Lellis, L|Semeraro, D|Colucci, G|Hormazdi, M|Rakhshani, N|Cama, A|Piantelli, M|Iacobelli, S|Russo, A|Mariani-Costantini, R
PMID: 16760302
Journal: Eur Urol. 2006 Oct;50(4):770-5; discussion 776. Epub 2006 May 2.
Title: Elevated microsatellite instability at selected tetranucleotide repeats does not correlate with clinicopathologic features of bladder cancer.
Author: Burger, Maximilian|Burger, Sarah J|Denzinger, Stefan|Wild, Peter J|Wieland, Wolf F|Blaszyk, Hagen|Obermann, Ellen C|Stoehr, Robert|Hartmann, Arndt
PMID: 16762487
Journal: Mod Pathol. 2006 Oct;19(10):1302-9. Epub 2006 Jun 9.
Title: Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer.
Author: Lugli, Alessandro|Zlobec, Inti|Gunthert, Ursula|Minoo, Parham|Baker, Kristi|Tornillo, Luigi|Terracciano, Luigi|Jass, Jeremy R
PMID: 16763611
Journal: Eur J Cancer. 2006 Jul;42(10):1357-61. Epub 2006 Jun 9.
Title: Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years.
Author: Alsop, Kathryn|Mead, Leeanne|Smith, Letitia D|Royce, Simon G|Tesoriero, Andrea A|Young, Joanne P|Haydon, Andrew|Grubb, Garry|Giles, Graham G|Jenkins, Mark A|Hopper, John L|Southey, Melissa C
PMID: 16765042
Journal: J Pediatr. 2006 Jun;148(6):837-9.
Title: Mutations in the DNA mismatch repair gene MLH1 associated with early-onset colon cancer.
Author: Marcos, Irene|Borrego, Salud|Urioste, Miguel|Garcia-Valles, Carmen|Antinolo, Guillermo
PMID: 16769400
Journal: Am J Gastroenterol. 2006 Jun;101(6):1313-9.
Title: Mismatch repair polymorphisms and colorectal polyps: hMLH1-93G>A variant modifies risk associated with smoking.
Author: Yu, Joon-Ho|Bigler, Jeannette|Whitton, John|Potter, John D|Ulrich, Cornelia M
PMID: 16771955
Journal: Dis Colon Rectum. 2006 Aug;49(8):1193-202.
Title: Tumor buds show reduced expression of laminin-5 gamma 2 chain in DNA mismatch repair deficient colorectal cancer.
Author: Shinto, Eiji|Baker, Kristi|Tsuda, Hitoshi|Mochizuki, Hidetaka|Ueno, Hideki|Matsubara, Osamu|Foulkes, William D|Jass, Jeremy R
PMID: 16773493
Journal: Hum Pathol. 2006 Jul;37(7):831-8. Epub 2006 May 19.
Title: Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter.
Author: Yearsley, Martha|Hampel, Heather|Lehman, Amy|Nakagawa, Hidewaki|de la Chapelle, Albert|Frankel, Wendy L
PMID: 16784982
Journal: Oncol Rep. 2006 Jul;16(1):41-7.
Title: Loss of protein expression of hMLH1 and hMSH2 with double primary carcinomas of the stomach and colorectum.
Author: Yamamoto, Manabu|Taguchi, Kenichi|Baba, Hideo|Endo, Kazuya|Kohnoe, Shunji|Okamura, Takeshi|Maehara, Yoshihiko
PMID: 16786121
Journal: Nat Genet. 2006 Jul;38(7):787-93. Epub 2006 Jun 25.
Title: CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Author: Weisenberger, Daniel J|Siegmund, Kimberly D|Campan, Mihaela|Young, Joanne|Long, Tiffany I|Faasse, Mark A|Kang, Gyeong Hoon|Widschwendter, Martin|Weener, Deborah|Buchanan, Daniel|Koh, Hoey|Simms, Lisa|Barker, Melissa|Leggett, Barbara|Levine, Joan|Kim, Myun
PMID: 16804544
Journal: N Engl J Med. 2006 Jun 29;354(26):2751-63.
Title: Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.
Author: Barnetson, Rebecca A|Tenesa, Albert|Farrington, Susan M|Nicholl, Iain D|Cetnarskyj, Roseanne|Porteous, Mary E|Campbell, Harry|Dunlop, Malcolm G
PMID: 16807412
Journal: World J Gastroenterol. 2006 Jul 7;12(25):4074-7.
Title: Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families.
Author: Wang, Xu-Lin|Yuan, Ying|Zhang, Su-Zhan|Cai, Shan-Rong|Huang, Yan-Qin|Jiang, Qiang|Zheng, Shu
PMID: 16810763
Journal: Fam Cancer. 2006;5(4):353-8. Epub 2006 Jul 12.
Title: The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer.
Author: Halvarsson, Britta|Lindblom, Annika|Rambech, Eva|Lagerstedt, Kristina|Nilbert, Mef
PMID: 16817031
Journal: J Pediatr Gastroenterol Nutr. 2006 Jul;43(1):5-15.
Title: Genetic predisposition to colorectal cancer: new pieces in the pediatric puzzle.
Author: Durno, Carol A|Gallinger, Steven
PMID: 16819371
Journal: Genet Mol Res. 2006 Jun 30;5(2):315-22.
Title: Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer.
Author: Clarizia, Alessandra D|Bastos-Rodrigues, Luciana|Pena, Heloisa B|Anacleto, Charles|Rossi, Benedito|Soares, Fernando A|Lopes, Ademar|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria|Simpson, Andrew J G|Pena, Sergio D J
PMID: 16819711
Journal: Neoplasia. 2006 Jun;8(6):458-64.
Title: Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Ogino, Shuji|Brahmandam, Mohan|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 16820091
Journal: Oncol Rep. 2006 Aug;16(2):429-35.
Title: Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas.
Author: Ye, Chuanzhong|Shrubsole, Martha J|Cai, Qiuyin|Ness, Reid|Grady, William M|Smalley, Walter|Cai, Hui|Washington, Kay|Zheng, Wei
PMID: 16820927
Journal: J Mol Histol. 2006 Sep;37(5-7):271-83. Epub 2006 Jul 4.
Title: DNA mismatch repair and Lynch syndrome.
Author: Plotz, Guido|Zeuzem, Stefan|Raedle, Jochen
PMID: 16821093
Journal: J Invest Dermatol. 2006 Oct;126(10):2302-7. Epub 2006 Jul 6.
Title: Value of MLH1 and MSH2 mutations in the appearance of Muir-Torre syndrome phenotype in HNPCC patients presenting sebaceous gland tumors or keratoacanthomas.
Author: Ponti, Giovanni|Losi, Lorena|Pedroni, Monica|Lucci-Cordisco, Emanuela|Di Gregorio, Carmela|Pellacani, Giovanni|Seidenari, Stefania
PMID: 16826164
Journal: Fam Cancer. 2006;5(4):369-71. Epub 2006 Jul 7.
Title: Survival from colorectal carcinoma in HNPCC families as compared to the general population in Lithuania--initial results.
Author: Elsakov, Pavel|Kurtinaitis, Juozas
PMID: 16826317
Journal: Neoplasma. 2006;53(4):269-76.
Title: Novel and recurrent germline alterations in the MLH1 and MSH2 genes identified in hereditary nonpolyposis colorectal cancer patients in Slovakia.
Author: Zavodna, K|Bujalkova, M|Krivulcik, T|Alemayehu, A|Skorvaga, M|Marra, G|Fridrichova, I|Jiricny, J|Bartosova, Z
PMID: 16830052
Journal: Arkh Patol. 2006 May-Jun;68(3):31-5.
Title: [Morphological and immunohistogenetical features of colon cancer in children].
Author: Talalaev, A G|Tertychnyi, A S|Konovalov, D M|Val'kov, A Iu|Marenich, N S
PMID: 16830623
Journal: Rev Neurol (Paris). 2006 Jun;162(6-7):741-6.
Title: [Turcot's syndrome confirmed by molecular biological tests].
Author: Jeannin, S|Lebrun, C|Van Den Bos, F|Olschwang, S|Bourg, V|Frenay, M
PMID: 16840983
Journal: J Pathol. 2006 Oct;210(2):147-54.
Title: Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Ogino, S|Kawasaki, T|Kirkner, G J|Ogawa, A|Dorfman, I|Loda, M|Fuchs, C S
PMID: 16850502
Journal: Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4244-50.
Title: Inverse effects of mucin on survival of matched hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer patients.
Author: You, Jeng-Fu|Hsieh, Ling-Ling|Changchien, Chung Rong|Chen, Jinn-Shiun|Chen, Jim-Ray|Chiang, Jy-Ming|Yeh, Chien Yuh|Hsieh, Pao-Shiu|Fan, Chung-Wei|Liu, Chun-Ting|Tang, Reiping
PMID: 16857798
Journal: Pathol Res Pract. 2006;202(9):663-70.
Title: Prognostic significance of histological features and biological parameters in stage I (pT1 and pT2) colorectal adenocarcinoma.
Author: Losi, Lorena|Ponti, Giovanni|Gregorio, Carmela Di|Marino, Massimiliano|Rossi, Giuseppina|Pedroni, Monica|Benatti, Piero|Roncucci, Luca|de Leon, Maurizio Ponz
PMID: 16860493
Journal: Hum Pathol. 2006 Aug;37(8):1022-31. Epub 2006 May 26.
Title: Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer-a tissue microarray-based approach.
Author: Lugli, Alessandro|Zlobec, Inti|Minoo, Parham|Baker, Kristi|Tornillo, Luigi|Terracciano, Luigi|Jass, Jeremy R
PMID: 16867865
Journal: World J Gastroenterol. 2006 Jul 28;12(28):4485-91.
Title: Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking.
Author: Brand, Rhonda M|Jones, David D|Lynch, Henry T|Brand, Randall E|Watson, Patrice|Ashwathnayaran, Ramesh|Roy, Hemant K
PMID: 16874859
Journal: Cancer Res. 2006 Aug 1;66(15):7502-8.
Title: MLH3 mutation in endometrial cancer.
Author: Taylor, Nicholas P|Powell, Matthew A|Gibb, Randall K|Rader, Janet S|Huettner, Phyllis C|Thibodeau, Stephen N|Mutch, David G|Goodfellow, Paul J
PMID: 16885347
Journal: Gastroenterology. 2006 Aug;131(2):439-44.
Title: Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.
Author: Di Gregorio, Carmela|Frattini, Milo|Maffei, Stefania|Ponti, Giovanni|Losi, Lorena|Pedroni, Monica|Venesio, Tiziana|Bertario, Lucio|Varesco, Liliana|Risio, Mauro|Ponz de Leon, Maurizio
PMID: 16890597
Journal: J Pathol. 2006 Nov;210(3):344-50.
Title: Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas.
Author: Judson, H|Stewart, A|Leslie, A|Pratt, N R|Baty, D U|Steele, R J C|Carey, F A
PMID: 16902913
Journal: Head Neck. 2006 Oct;28(10):909-15.
Title: Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.
Author: Frattini, Milo|Perrone, Federica|Suardi, Simona|Balestra, Debora|Caramuta, Stefano|Colombo, Federica|Licitra, Lisa|Cantu, Giulio|Pierotti, Marco A|Pilotti, Silvana
PMID: 16906516
Journal: J Clin Oncol. 2006 Sep 10;24(26):4285-92. Epub 2006 Aug 14.
Title: Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.
Author: Goecke, Timm|Schulmann, Karsten|Engel, Christoph|Holinski-Feder, Elke|Pagenstecher, Constanze|Schackert, Hans K|Kloor, Matthias|Kunstmann, Erdmute|Vogelsang, Holger|Keller, Gisela|Dietmaier, Wolfgang|Mangold, Elisabeth|Friedrichs, Nicolaus|Propping, Peter
PMID: 16908935
Journal: Curr Top Microbiol Immunol. 2006;310:141-78.
Title: DNA methylation profiles of female steroid hormone-driven human malignancies.
Author: Campan, M|Weisenberger, D J|Laird, P W
PMID: 16909910
Journal: Tidsskr Nor Laegeforen. 2006 Aug 10;126(15):1937-9.
Title: [Handling of hereditary intestinal cancer].
Author: Moller, Pal|Stormorken, Astrid|Apold, Jaran
PMID: 16915319
Journal: Int J Cancer. 2006 Dec 1;119(11):2513-9.
Title: Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis.
Author: Ozaki, Kazuhide|Nagasaka, Takeshi|Notohara, Kenji|Kambara, Takeshi|Takeda, Masanori|Sasamoto, Hiromi|Jass, Jeremy R|Tanaka, Noriaki|Matsubara, Nagahide
PMID: 16929496
Journal: Am J Surg Pathol. 2006 Sep;30(9):1175-83.
Title: Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.
Author: Ogino, Shuji|Odze, Robert D|Kawasaki, Takako|Brahmandam, Mohan|Kirkner, Gregory J|Laird, Peter W|Loda, Massimo|Fuchs, Charles S
PMID: 16931963
Journal: World J Gastroenterol. 2006 Aug 7;12(29):4745-9.
Title: Role of detection of microsatellite instability in Chinese with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer.
Author: Liu, Wen-Zhi|Jin, Feng|Zhang, Zhen-Hai|Wang, Shu-Bao
PMID: 16937450
Journal: Am J Clin Pathol. 2006 Oct;126(4):564-71.
Title: Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: an immunohistochemical study of serrated lesions "caught in the act".
Author: Sheridan, Todd B|Fenton, Hubert|Lewin, Marc R|Burkart, Ashlie L|Iacobuzio-Donahue, Christine A|Frankel, Wendy L|Montgomery, Elizabeth
PMID: 16938659
Journal: Br J Cancer. 2006 Sep 18;95(6):752-6. Epub 2006 Aug 29.
Title: MSH6 germline mutations in early-onset colorectal cancer patients without family history of the disease.
Author: Pinto, C|Veiga, I|Pinheiro, M|Mesquita, B|Jeronimo, C|Sousa, O|Fragoso, M|Santos, L|Moreira-Dias, L|Baptista, M|Lopes, C|Castedo, S|Teixeira, M R
PMID: 16940983
Journal: Clin Cancer Res. 2006 Sep 1;12(17):5104-11.
Title: DNA repair pathway profiling and microsatellite instability in colorectal cancer.
Author: Yu, Jinsheng|Mallon, Mary A|Zhang, Wanghai|Freimuth, Robert R|Marsh, Sharon|Watson, Mark A|Goodfellow, Paul J|McLeod, Howard L
PMID: 16951227
Journal: Nat Genet. 2006 Oct;38(10):1178-83. Epub 2006 Sep 3.
Title: Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.
Author: Chan, Tsun Leung|Yuen, Siu Tsan|Kong, Chi Kwan|Chan, Yee Wai|Chan, Annie S Y|Ng, Wai Fu|Tsui, Wai Yin|Lo, Michelle W S|Tam, Wing Yip|Li, Vivian S W|Leung, Suet Yi
PMID: 16951683
Journal: Gastroenterology. 2006 Sep;131(3):729-37.
Title: Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients.
Author: Sinicrope, Frank A|Rego, Rafaela L|Halling, Kevin C|Foster, Nathan|Sargent, Daniel J|La Plant, Betsy|French, Amy J|Laurie, John A|Goldberg, Richard M|Thibodeau, Stephen N|Witzig, Thomas E
PMID: 16952542
Journal: Genes Chromosomes Cancer. 2006 Dec;45(12):1106-10.
Title: A de novo MLH1 germ line mutation in a 31-year-old colorectal cancer patient.
Author: Plasilova, Martina|Zhang, Jian|Okhowat, Roberta|Marra, Giancarlo|Mettler, Markus|Mueller, Hansjakob|Heinimann, Karl
PMID: 16955466
Journal: Eur J Cancer. 2006 Nov;42(16):2802-6. Epub 2006 Sep 11.
Title: Identification of germline MLH1 alterations in familial prostate cancer.
Author: Fredriksson, H|Ikonen, T|Autio, V|Matikainen, M P|Helin, H J|Tammela, T L J|Koivisto, P A|Schleutker, J
PMID: 16963262
Journal: J Genet Couns. 2006 Oct;15(5):339-47.
Title: Assessing the predictive accuracy of hMLH1 and hMSH2 mutation probability models.
Author: Jasperson, Kory W|Lowstuter, Katrina|Weitzel, Jeffrey N
PMID: 16969708
Journal: Cancer Detect Prev. 2006;30(4):333-40.
Title: A novel mutation detection approach of hMLH1 and hMSH2 genes for screening of colorectal cancer.
Author: Yuan, Ziqiang|Legendre, Benjamin Jr|Sreeramoju, Prashanth|Lowes, Christina|Reynolds, Davis|Bennett, Anna|Kent, Tara Sotsky|Miller, Agnes|Zhu, Jim|Weber, Thomas K
PMID: 16971051
Journal: Int J Cancer. 2006 Nov 15;119(10):2272-8.
Title: APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer.
Author: Iacopetta, Barry|Grieu, Fabienne|Li, Wei|Ruszkiewicz, Andrew|Caruso, Maria|Moore, James|Watanabe, Goh|Kawakami, Kazuyuki
PMID: 16981189
Journal: Pathol Int. 2006 Oct;56(10):597-603.
Title: Age-related alteration in the association of microsatellite instability with absent hMLH1 expression and histological types of colorectal carcinoma.
Author: Arai, Tomio|Sugai, Tamotsu|Kasahara, Ichiro|Sawabe, Motoji|Honma, Naoko|Aida, Junko|Nakamura, Shin-Ichi|Takubo, Kaiyo
PMID: 16984616
Journal: Hum Pathol. 2006 Nov;37(11):1498-502. Epub 2006 Sep 25.
Title: Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene.
Author: Banville, Niamh|Geraghty, Robert|Fox, Edward|Leahy, Dermot T|Green, Andrew|Keegan, Denise|Geoghegan, Justin|O'Donoghue, Diarmuid|Hyland, John|Sheahan, Kieran
PMID: 16996571
Journal: JAMA. 2006 Sep 27;296(12):1469-78.
Title: Prediction of MLH1 and MSH2 mutations in Lynch syndrome.
Author: Balmana, Judith|Stockwell, David H|Steyerberg, Ewout W|Stoffel, Elena M|Deffenbaugh, Amie M|Reid, Julia E|Ward, Brian|Scholl, Thomas|Hendrickson, Brant|Tazelaar, John|Burbidge, Lynn Anne|Syngal, Sapna
PMID: 17003395
Journal: Cancer Genet Cytogenet. 2006 Oct 15;170(2):121-8.
Title: Variations in exon 7 of the MSH2 gene and susceptibility to gastrointestinal cancer in a Chinese population.
Author: Fan, Yimei|Liu, Xiaorong|Zhang, Huan|Dai, Jin|Zhang, Xiaomei|Zhu, Ming|Gao, Xiang|Wang, Yaping
PMID: 17011982
Journal: Pol J Pathol. 2006;57(2):105-11.
Title: Correlation of microsatellite status, proliferation, apoptotic and selected immunohistochemical markers in colorectal carcinoma studied with tissue microarray.
Author: Okon, Krzysztof|Demczuk, Sergiusz|Klimkowska, Agnieszka|Wojcik, Piotr|Osuch, Czeslaw|Papla, Boleslaw|Stachura, Jerzy
PMID: 17019973
Journal: Am J Gastroenterol. 2006 Dec;101(12):2818-25.
Title: Microsatellite instability accounts for tumor site-related differences in clinicopathologic variables and prognosis in human colon cancers.
Author: Sinicrope, Frank A|Rego, Rafaela L|Foster, Nathan|Sargent, Daniel J|Windschitl, Harold E|Burgart, Lawrence J|Witzig, Thomas E|Thibodeau, Stephen N
PMID: 17026563
Journal: Clin Genet. 2006 Nov;70(5):388-95.
Title: Inherited association of breast and colorectal cancer: limited role of CHEK2 compared with high-penetrance genes.
Author: Naseem, H|Boylan, J|Speake, D|Leask, K|Shenton, A|Lalloo, F|Hill, J|Trump, D|Evans, D G R
PMID: 17026620
Journal: Br J Cancer. 2006 Nov 6;95(9):1239-43.
Title: The role of MYH and microsatellite instability in the development of sporadic colorectal cancer.
Author: Colebatch, A|Hitchins, M|Williams, R|Meagher, A|Hawkins, N J|Ward, R L
PMID: 17031395
Journal: Cancer Sci. 2006 Dec;97(12):1335-42.
Title: Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions.
Author: Ogawa, Taishi|Yoshida, Tsutomu|Tsuruta, Tomoko|Saigenji, Katsunori|Okayasu, Isao
PMID: 17032312
Journal: Chin J Dig Dis. 2006;7(4):197-205.
Title: Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.
Author: Sheng, Jian Qiu|Chan, Tsun Leung|Chan, Yee Wai|Huang, Ji Sheng|Chen, Ji Gui|Zhang, Ming Zhi|Guo, Xiu Lan|Mu, Hong|Chan, Annie Sy|Li, Shi Rong|Yuen, Siu Tsan|Leung, Suet Yi
PMID: 17054581
Journal: Arch Iran Med. 2006 Oct;9(4):381-9.
Title: Genetics of hereditary nonpolyposis colorectal cancer.
Author: Akrami, Seyed Mohammad
PMID: 17061614
Journal: J Mol Diagn. 2006 Nov;8(5):540-3.
Title: Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology.
Author: Benlloch, Susana|Paya, Artemio|Alenda, Cristina|Bessa, Xavier|Andreu, Montserrat|Jover, Rodrigo|Castells, Antoni|Llor, Xavier|Aranda, F Ignacio|Massuti, Bartomeu
PMID: 17065421
Journal: J Mol Diagn. 2006 Nov;8(5):582-8.
Title: CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17065427
Journal: Cancer Genet Cytogenet. 2006 Nov;171(1):17-23.
Title: Single-nucleotide polymorphisms of mismatch repair genes in healthy Chinese individuals and sporadic colorectal cancer patients.
Author: Mei, Qian|Yan, Hong-Li|Ding, Fei-Xiang|Xue, Geng|Huang, Jing-Jing|Wang, Yu-Zhao|Sun, Shu-Han
PMID: 17074586
Journal: J Mol Histol. 2006 Sep;37(5-7):301-7. Epub 2006 Nov 2.
Title: The role of the human DNA mismatch repair gene hMSH2 in DNA repair, cell cycle control and apoptosis: implications for pathogenesis, progression and therapy of cancer.
Author: Seifert, Markus|Reichrath, Jorg
PMID: 17080293
Journal: Digestion. 2006;74(1):58-67. Epub 2006 Mar 3.
Title: Frequency of hereditary non-polyposis colorectal cancer among unselected patients with colorectal cancer in Germany.
Author: Lamberti, C|Mangold, E|Pagenstecher, C|Jungck, M|Schwering, D|Bollmann, M|Vogel, J|Kindermann, D|Nikorowitsch, R|Friedrichs, N|Schneider, B|Houshdaran, F|Schmidt-Wolf, I G H|Friedl, W|Propping, P|Sauerbruch, T|Buttner, R|Mathiak, M
PMID: 17095871
Journal: Dis Colon Rectum. 2006 Oct;49(10 Suppl):S23-9.
Title: Frequency of immunohistochemical loss of mismatch repair protein in double primary cancers of the colorectum and stomach in Japan.
Author: Hayashi, Tetsuji|Arai, Masami|Ueno, Masashi|Kinoshita, Hirokatsu|Tada, Yurika|Koizumi, Koichi|Miki, Yoshio|Yamaguchi, Toshiharu|Kato, Yo|Utsunomiya, Joji|Muto, Tetsuichiro|Sugihara, Kenichi
PMID: 17106811
Journal: J Nutr. 2006 Dec;136(12):3015-21.
Title: Dietary folate and APC mutations in sporadic colorectal cancer.
Author: de Vogel, Stefan|van Engeland, Manon|Luchtenborg, Margreet|de Bruine, Adriaan P|Roemen, Guido M J M|Lentjes, Marjolein H F M|Goldbohm, R Alexandra|van den Brandt, Piet A|de Goeij, Anton F P M|Weijenberg, Matty P
PMID: 17116713
Journal: Br J Cancer. 2006 Dec 18;95(12):1678-82. Epub 2006 Nov 21.
Title: Very low prevalence of germline MSH6 mutations in hereditary non-polyposis colorectal cancer suspected patients with colorectal cancer without microsatellite instability.
Author: Kets, C M|van Krieken, J H J M|Hebeda, K M|Wezenberg, S J|Goossens, M|Brunner, H G|Ligtenberg, M J L|Hoogerbrugge, N
PMID: 17117178
Journal: Am J Surg Pathol. 2006 Dec;30(12):1491-501.
Title: Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points.
Author: O'Brien, Michael J|Yang, Shi|Mack, Charline|Xu, Huihong|Huang, Christopher S|Mulcahy, Elizabeth|Amorosino, Mark|Farraye, Francis A
PMID: 17122504
Journal: Surg Oncol. 2006 Aug;15(2):97-106.
Title: Loss of p27 expression and microsatellite instability in sporadic colorectal cancer.
Author: Sarli, Leopoldo|Bottarelli, Lorena|Azzoni, Cinzia|Campanini, Nicoletta|Di Cola, Gabriella|Barilli, Angela Luciana|Marchesi, Federico|Mazzeo, Antonio|Salvemini, Carlo|Morari, Silvia|Di Mauro, Davide|Donadei, Enrico|Necchi, Fransesca|Roncoroni, Luigi|Bordi,
PMID: 17123889
Journal: Ugeskr Laeger. 2006 Nov 13;168(46):4009-11.
Title: [Hyperplastic colorectal polyposis].
Author: de Neergaard, Signe H|Bernstein, Inge T|Holck, Susanne
PMID: 17125656
Journal: Rev Med Chil. 2006 Jul;134(7):841-8. Epub 2006 Aug 29.
Title: [Hereditary colorectal cancer: Molecular analysis of APC and MLH1 genes].
Author: Bellolio R, Felipe|Alvarez V, Karin|De la Fuente L, Marjorie|Leon G, Francisca|Fullerton M, Demian A|Soto D, Gonzalo|Carvallo de S Q, Pilar|Lopez-Kostner, Francisco
PMID: 17130966
Journal: J Natl Cancer Inst. 2006 Dec 6;98(23):1731-8.
Title: Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.
Author: Samowitz, Wade S|Albertsen, Hans|Sweeney, Carol|Herrick, Jennifer|Caan, Bette J|Anderson, Kristin E|Wolff, Roger K|Slattery, Martha L
PMID: 17148775
Journal: Cell Oncol. 2006;28(5-6):247-57.
Title: Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Author: Derks, Sarah|Postma, Cindy|Moerkerk, Peter T M|van den Bosch, Sandra M|Carvalho, Beatriz|Hermsen, Mario A J A|Giaretti, Walter|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon
PMID: 17167178
Journal: Int J Gynecol Cancer. 2006 Nov-Dec;16(6):1980-6.
Title: Increased risk for abnormalities on perioperative colon screening in patients with microsatellite instability-positive endometrial carcinoma.
Author: Buttin, B M|Powell, M A|Goodfellow, P J|Lewin, S N|Gibb, R K|Mutch, D G
PMID: 17177835
Journal: Rev Med Chil. 2006 Oct;134(10):1221-9. Epub 2006 Dec 13.
Title: [Microsatellite instability among patients with colorectal cancer].
Author: Montenegro, Yenny|Ramirez-Castro, Jose Luis|Isaza, Luis Fernando|Bedoya, Gabriel|Muneton-Pena, Carlos Mario
PMID: 17186090
Journal: Clin Cancer Res. 2006 Dec 15;12(24):7347-52.
Title: Methylation of serum DNA is an independent prognostic marker in colorectal cancer.
Author: Wallner, Maike|Herbst, Andreas|Behrens, Andrea|Crispin, Alexander|Stieber, Petra|Goke, Burkhard|Lamerz, Rolf|Kolligs, Frank T
PMID: 17189406
Journal: Pathol Oncol Res. 2006;12(4):228-33. Epub 2006 Dec 25.
Title: Two germline alterations in mismatch repair genes found in a HNPCC patient with poor family history.
Author: Kamory, Eniko|Tanyi, Miklos|Kolacsek, Orsolya|Olasz, Laszlo|Toth, Laszlo|Damjanovich, Laszlo|Csuka, Orsolya
PMID: 17189986
Journal: Cancer Biomark. 2006;2(1-2):37-49.
Title: New aspects in molecular diagnosis of Lynch syndrome (HNPCC).
Author: Fridrichova, Ivana
PMID: 17192058
Journal: World J Gastroenterol. 2006 Dec 28;12(48):7848-51.
Title: Novel MLH1 frameshift mutation in an extended hereditary nonpolyposis colorectal cancer family.
Author: Kadiyska, Tanya-Kirilova|Kaneva, Radka-Petrova|Nedin, Dimitar-Georgiev|Alexandrova, Alexandrina-Borisova|Gegova, Antonina-Todorova|Lalchev, Stoyan-Ganchev|Christova, Tatyana|Mitev, Vanio-Ivanov|Horst, Juergen|Bogdanova, Nadja|Kremensky, Ivo-Marinov
PMID: 17203532
Journal: Magy Onkol. 2006;50(4):349-59. Epub 2007 Jan 10.
Title: [Developments in cancer management by innovative genomics. 2006 report of the National Cancer Consortium].
Author: Timar, Jozsef|Kasler, Miklos|Katai, Jozsef|Soos, Miklos|Mathiasz, Dora|Romany, Anna|Patthy, Laszlo|Kovacs, Gabor|Jozsa, Adrienn|Szilak, Laszlo|Forrai, Tamas
PMID: 17216011
Journal: Hum Genet. 2006 Apr;119(3):360.
Title: Gene symbol: MLH1. Disease: colorectal cancer, non-polyposis.
Author: Kadiyska, T K|Bogdanova, N
PMID: 17230646
Journal: J Gastroenterol. 2006 Dec;41(12):1186-96.
Title: Early genetic instability of both epithelial and stromal cells in esophageal squamous cell carcinomas, contrasted with Barrett's adenocarcinomas.
Author: Shiraishi, Hiroaki|Mikami, Tetuo|Yoshida, Tsutomu|Tanabe, Satoshi|Kobayashi, Nobuyuki|Watanabe, Masahiko|Okayasu, Isao
PMID: 17287898
Journal: Oncology. 2006;71(1-2):124-30. Epub 2007 Mar 9.
Title: Mild inflammation accelerates colon carcinogenesis in Mlh1-deficient mice.
Author: Taniguchi, Kazuki|Kakinuma, Shizuko|Tokairin, Yutaka|Arai, Masami|Kohno, Hiroyuki|Wakabayashi, Keiji|Imaoka, Tatsuhiko|Ito, Eisaku|Koike, Morio|Uetake, Hiroyuki|Nishimura, Mayumi|Yamauchi, Kazumi|Sugihara, Ken-ichi|Shimada, Yoshiya
PMID: 17347588
Journal: Magy Seb. 2006 Dec;59(6):411-20.
Title: [Fenotypical diversity of hereditary non-polyposis colorectal carcinoma. Pedigree and genetical analysis of two mutation carrier patients].
Author: Tanyi, Miklos|Kanyari, Zsolt|Juhasz, Balazs|Lukacs, Geza|Olasz, Judit|Kamory, Eniko|Csuka, Orsolya|Toth, Laszlo|Damjanovich, Laszlo
PMID: 17432081
Journal: Verh Dtsch Ges Pathol. 2006;90:18-24.
Title: Types of colorectal adenoma.
Author: Lugli, A|Jass, J R
PMID: 17867575
Journal: Verh Dtsch Ges Pathol. 2006;90:236-43.
Title: [A new quantitative DNA-methylation analysis of MSI colorectal cancers helps to separate sporadic colorectal cancers from HNPCC-candidates].
Author: Bettstetter, M|Rummele, P|Hofstadter, F|Dietmaier, W
PMID: 17867602
Journal: J Cancer Res Ther. 2006 Jul-Sep;2(3):97-9.
Title: Proportionate increase in incidence of colorectal cancer at an age below 40 years: an observation.
Author: Pal, Madhumay
PMID: 17998686
Journal: Hered Cancer Clin Pract. 2006 May 15;4(2):90-3.
Title: MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer.
Author: Stormorken, Astrid|Heintz, Karen-Marie|Andresen, Per Arne|Hovig, Eivind|Moller, Pal
PMID: 20223013
Journal: Hered Cancer Clin Pract. 2006 May 15;4(2):94-102.
Title: The Association of the COMT V158M Polymorphism with Endometrial/Ovarian Cancer in HNPCC Families Adhering to the Amsterdam Criteria.
Author: Ashton, Katie A|Meldrum, Cliff J|McPhillips, Mary L|Suchy, Janina|Kurzawski, Grzegorz|Lubinski, Jan|Scott, Rodney J
PMID: 20223014
Journal: Int J Colorectal Dis. 2007 Feb;22(2):175-81. Epub 2006 Jun 20.
Title: Colorectal cancer in a population with endemic Schistosoma mansoni: is this an at-risk population?
Author: Madbouly, Khaled M|Senagore, Anthony J|Mukerjee, Abir|Hussien, Ahmed M|Shehata, M A|Navine, Philippa|Delaney, Conor P|Fazio, Victor W
PMID: 16786317
Journal: J Clin Pathol. 2007 May;60(5):534-9. Epub 2006 Jun 30.
Title: Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status.
Author: Lugli, A|Zlobec, I|Baker, K|Minoo, P|Tornillo, L|Terracciano, L|Jass, J R
PMID: 16816167
Journal: Cancer Lett. 2007 Apr 8;248(1):89-95. Epub 2006 Jul 11.
Title: Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.
Author: Pistorius, Steffen|Gorgens, Heike|Plaschke, Jens|Hoehl, Ruth|Kruger, Stefan|Engel, Christoph|Saeger, Hans-Detlev|Schackert, Hans K
PMID: 16837128
Journal: J Cancer Res Clin Oncol. 2007 Jan;133(1):65-70. Epub 2006 Aug 11.
Title: Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer.
Author: Chaksangchaichot, P|Punyarit, P|Petmitr, S
PMID: 16902769
Journal: Int J Colorectal Dis. 2007 Feb;22(2):115-26.
Title: Distinct molecular patterns based on proximal and distal sporadic colorectal cancer: arguments for different mechanisms in the tumorigenesis.
Author: Azzoni, Cinzia|Bottarelli, Lorena|Campanini, Nicoletta|Di Cola, Gabriella|Bader, Giovanni|Mazzeo, Antonio|Salvemini, Carlo|Morari, Silvia|Di Mauro, Davide|Donadei, Enrico|Roncoroni, Luigi|Bordi, Cesare|Sarli, Leopoldo
PMID: 17021745
Journal: Oncogene. 2007 Apr 12;26(17):2513-7. Epub 2006 Oct 9.
Title: No evidence for dual role of loss of heterozygosity in hereditary non-polyposis colorectal cancer.
Author: Tuupanen, S|Karhu, A|Jarvinen, H|Mecklin, J P|Launonen, V|Aaltonen, L A
PMID: 17043646
Journal: Cancer Gene Ther. 2007 Jan;14(1):98-104.
Title: Persistent mismatch repair deficiency following targeted correction of hMLH1.
Author: Weiss, M B|Vitolo, M I|Baerenfaller, K|Marra, G|Park, B H|Bachman, K E
PMID: 17082796
Journal: Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title: Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Yamaji, Taiki|Loda, Massimo|Fuchs, Charles S
PMID: 17086168
Journal: Gastroenterology. 2007 Jan;132(1):127-38.
Title: The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
Author: Goel, Ajay|Nagasaka, Takeshi|Arnold, Christian N|Inoue, Toru|Hamilton, Cody|Niedzwiecki, Donna|Compton, Carolyn|Mayer, Robert J|Goldberg, Richard|Bertagnolli, Monica M|Boland, C Richard
PMID: 17087942
Journal: Carcinogenesis. 2007 Apr;28(4):769-76.
Title: Microsatellite instability in aberrant crypt foci from patients without concurrent colon cancer.
Author: Greenspan, Emily J|Cyr, Jennifer L|Pleau, Devon C|Levine, Joel|Rajan, Thiruchandurai V|Rosenberg, Daniel W|Heinen, Christopher D
PMID: 17088260
Journal: Int J Cancer. 2007 Feb 1;120(3):656-63.
Title: Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.
Author: Slattery, Martha L|Curtin, Karen|Sweeney, Carol|Levin, Theodore R|Potter, John|Wolff, Roger K|Albertsen, Hans|Samowitz, Wade S
PMID: 17096326
Journal: Int J Colorectal Dis. 2007 Jul;22(7):777-82.
Title: Assessment of microsatellite instability in colorectal carcinoma at an Indian center.
Author: Pandey, Vijay|Prabhu, Jyothi S|Payal, K|Rajan, Veena|Deepak, C|Barde, Shubhada|Jagannath, P|Borges, Anita|Sridhar, T S
PMID: 17160686
Journal: Fam Cancer. 2007;6(1):97-102.
Title: A missense germline mutation in exon 7 of the MSH2 gene in a HNPCC family from center-Italy.
Author: Bianchi, Francesca|Galizia, Eva|Porfiri, Emilio|Belvederesi, Laura|Catalani, Romina|Loretelli, Cristian|Bracci, Raffaella|Bearzi, Italo|Turchi, Chiara|Viel, Alessandra|Cellerino, Riccardo
PMID: 17165155
Journal: Mutat Res. 2007 Mar 1;616(1-2):60-9. Epub 2006 Dec 18.
Title: Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair.
Author: King, Audrey A|Shaughnessy, Daniel T|Mure, Kanae|Leszczynska, Joanna|Ward, William O|Umbach, David M|Xu, Zongli|Ducharme, Danica|Taylor, Jack A|Demarini, David M|Klein, Catherine B
PMID: 17178418
Journal: Int J Cancer. 2007 Mar 15;120(6):1232-8.
Title: Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability.
Author: Sinicrope, Frank A|Rego, Rafaela L|Garrity-Park, Megan M|Foster, Nathan R|Sargent, Daniel J|Goldberg, Richard M|Wiesenfeld, Myron|Witzig, Thomas E|Thibodeau, Stephen N|Burgart, Lawrence J
PMID: 17187355
Journal: Ann Surg Oncol. 2007 Mar;14(3):1229-36. Epub 2006 Dec 31.
Title: Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer.
Author: Maestro, M L|Vidaurreta, M|Sanz-Casla, M T|Rafael, S|Veganzones, S|Martinez, A|Aguilera, C|Herranz, M D|Cerdan, J|Arroyo, M
PMID: 17195912
Journal: Clin Cancer Res. 2007 Jan 1;13(1):356-61.
Title: Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors.
Author: Aaltonen, Lauri|Johns, Louise|Jarvinen, Heikki|Mecklin, Jukka-Pekka|Houlston, Richard
PMID: 17200375
Journal: Oncol Rep. 2007 Feb;17(2):351-4.
Title: Conditional nuclear localization of hMLH3 suggests a minor activity in mismatch repair and supports its role as a low-risk gene in HNPCC.
Author: Korhonen, Mari K|Raevaara, Tiina E|Lohi, Hannes|Nystrom, Minna
PMID: 17203173
Journal: Histopathology. 2007 Jan;50(1):131-50.
Title: Colorectal serrated adenocarcinoma.
Author: Makinen, M J
PMID: 17204027
Journal: Int J Cancer. 2007 Apr 1;120(7):1548-54.
Title: Mismatch repair polymorphisms and the risk of colorectal cancer.
Author: Berndt, Sonja I|Platz, Elizabeth A|Fallin, M Daniele|Thuita, Lucy W|Hoffman, Sandra C|Helzlsouer, Kathy J
PMID: 17205513
Journal: Hum Mol Genet. 2007 Feb 15;16(4):445-52. Epub 2007 Jan 8.
Title: The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations.
Author: Wanat, Jennifer J|Singh, Nikhil|Alani, Eric
PMID: 17210669
Journal: BMC Cancer. 2007 Jan 12;7:6.
Title: A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer.
Author: Middeldorp, Anneke|Jagmohan-Changur, Shantie|Helmer, Quinta|van der Klift, Heleen M|Tops, Carli M J|Vasen, Hans F A|Devilee, Peter|Morreau, Hans|Houwing-Duistermaat, Jeanine J|Wijnen, Juul T|van Wezel, Tom
PMID: 17222328
Journal: Cancer Lett. 2007 Jul 8;252(1):55-64. Epub 2007 Jan 16.
Title: The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.
Author: Kruger, Stefan|Engel, Christoph|Bier, Andrea|Silber, Ann-Sophie|Gorgens, Heike|Mangold, Elisabeth|Pagenstecher, Constanze|Holinski-Feder, Elke|von Knebel Doeberitz, Magnus|Royer-Pokora, Brigitte|Dechant, Stefan|Pox, Christian|Rahner, Nils|Muller, Annegret
PMID: 17224235
Journal: Int J Cancer. 2007 Apr 15;120(8):1684-8.
Title: Evidence for heritable predisposition to epigenetic silencing of MLH1.
Author: Chen, Huiping|Taylor, Nicholas P|Sotamaa, Kaisa M|Mutch, David G|Powell, Matthew A|Schmidt, Amy P|Feng, Sheng|Hampel, Heather L|de la Chapelle, Albert|Goodfellow, Paul J
PMID: 17230510
Journal: Int J Technol Assess Health Care. 2007 Winter;23(1):89-95.
Title: Cost-effectiveness of surveillance programs for families at high and moderate risk of hereditary non-polyposis colorectal cancer.
Author: Olsen, Kim R|Bojesen, Stig E|Gerdes, Anne-Marie M|Lindorff-Larsen, Karen|Bernstein, Inge T
PMID: 17234021
Journal: Fam Cancer. 2007;6(1):131-4.
Title: Family history is neglected in the work-up of patients with colorectal cancer: a quality assessment using cancer registry data.
Author: van Dijk, D A|Oostindier, M J|Kloosterman-Boele, W M|Krijnen, P|Vasen, H F A
PMID: 17237905
Journal: Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17239930
Journal: Gastroenterology. 2007 Jan;132(1):221-35.
Title: 5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.
Author: Luciani, M Gloria|Campregher, Christoph|Fortune, John M|Kunkel, Thomas A|Gasche, Christoph
PMID: 17241873
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Jan;10(1):67-9.
Title: [Study the value of screening hereditary nonpolyposis colorectal cancer kindreds by detecting the expression of hMLH1/hMSH2 with tissue microarray].
Author: Jin, Hei-Ying|Ding, Yi-Jiang|Geng, Jian-Xiang|Liu, Fei|Yang, Bo-Lin|Huang, Shu-Liang|Ding, Shu-Qin|Ge, Yong-Sheng
PMID: 17253179
Journal: Gastroenterology. 2007 Feb;132(2):527-30. Epub 2006 Nov 29.
Title: Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
Author: Will, Olivia|Carvajal-Carmona, Luis G|Gorman, Patricia|Howarth, Kimberley M|Jones, Angela M|Polanco-Echeverry, Guadalupe M|Chinaleong, Jo-Anne|Gunther, Thomas|Silver, Andrew|Clark, Susan K|Tomlinson, Ian
PMID: 17258725
Journal: Gastroenterology. 2007 Feb;132(2):633-44. Epub 2006 Nov 16.
Title: Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin.
Author: Jung, Barbara H|Beck, Stayce E|Cabral, Jennifer|Chau, Eddy|Cabrera, Betty L|Fiorino, Antonio|Smith, E Julieta|Bocanegra, Melanie|Carethers, John M
PMID: 17258738
Journal: Nat Clin Pract Oncol. 2007 Feb;4(2):130-4.
Title: Medulloblastoma, acute myelocytic leukemia and colonic carcinomas in a child with biallelic MSH6 mutations.
Author: Scott, Richard H|Mansour, Sahar|Pritchard-Jones, Kathryn|Kumar, Devinder|MacSweeney, Fergus|Rahman, Nazneen
PMID: 17259933
Journal: Gut. 2007 Jul;56(7):926-33. Epub 2007 Jan 31.
Title: Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study.
Author: Gylling, A|Abdel-Rahman, W M|Juhola, M|Nuorva, K|Hautala, E|Jarvinen, H J|Mecklin, J-P|Aarnio, M|Peltomaki, P
PMID: 17267619
Journal: Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title: TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17270239
Journal: Int J Cancer. 2007 May 1;120(9):1922-9.
Title: Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas.
Author: Kaz, Andrew|Kim, Young-Ho|Dzieciatkowski, Slavomir|Lynch, Henry|Watson, Patrice|Kay Washington, Mary|Lin, Li|Grady, William M
PMID: 17278092
Journal: J Natl Cancer Inst. 2007 Feb 7;99(3):244-52.
Title: Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors.
Author: Xicola, Rosa M|Llor, Xavier|Pons, Elisenda|Castells, Antoni|Alenda, Cristina|Pinol, Virginia|Andreu, Montserrat|Castellvi-Bel, Sergi|Paya, Artemio|Jover, Rodrigo|Bessa, Xavier|Giros, Anna|Duque, Jose M|Nicolas-Perez, David|Garcia, Ana M|Rigau, Joaquin|Gas
PMID: 17284719
Journal: J Gynecol Obstet Biol Reprod (Paris). 2007 Feb;36(1):68-71.
Title: [Lynch syndrome and gynaecologic's cancer: follow-up recommendations].
Author: Magri, K|Millon, G
PMID: 17293255
Journal: Clin Genet. 2007 Mar;71(3):232-7.
Title: MLH1 germline epimutations in selected patients with early-onset non-polyposis colorectal cancer.
Author: Valle, L|Carbonell, P|Fernandez, V|Dotor, A M|Sanz, M|Benitez, J|Urioste, M
PMID: 17309645
Journal: J Natl Cancer Inst. 2007 Feb 21;99(4):291-9.
Title: Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
Author: Lagerstedt Robinson, Kristina|Liu, Tao|Vandrovcova, Jana|Halvarsson, Britta|Clendenning, Mark|Frebourg, Thierry|Papadopoulos, Nickolas|Kinzler, Kenneth W|Vogelstein, Bert|Peltomaki, Paivi|Kolodner, Richard D|Nilbert, Mef|Lindblom, Annika
PMID: 17312306
Journal: Br J Nutr. 2007 Mar;97(3):430-4.
Title: Alcohol consumption and distinct molecular pathways to colorectal cancer.
Author: Bongaerts, Brenda W C|de Goeij, Anton F P M|de Vogel, Stefan|van den Brandt, Piet A|Goldbohm, R Alexandra|Weijenberg, Matty P
PMID: 17313702
Journal: Pathol Int. 2007 Apr;57(4):205-12.
Title: Microsatellite-unstable mucinous colorectal carcinoma occurring in the elderly: comparison with medullary type poorly differentiated adenocarcinoma.
Author: Arai, Tomio|Kasahara, Ichiro|Sawabe, Motoji|Kanazawa, Nobuo|Kuroiwa, Kojiro|Honma, Naoko|Aida, Junko|Takubo, Kaiyo
PMID: 17316416
Journal: BMC Cancer. 2007 Feb 22;7:33.
Title: HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.
Author: Dierssen, Jan Willem F|de Miranda, Noel F C C|Ferrone, Soldano|van Puijenbroek, Marjo|Cornelisse, Cees J|Fleuren, Gert Jan|van Wezel, Tom|Morreau, Hans
PMID: 17316446
Journal: Clin Cancer Res. 2007 Feb 15;13(4):1315-21.
Title: DNA mismatch repair initiates 6-thioguanine--induced autophagy through p53 activation in human tumor cells.
Author: Zeng, Xuehuo|Yan, Tao|Schupp, Jane E|Seo, Yuji|Kinsella, Timothy J
PMID: 17317843
Journal: J Med Genet. 2007 Jun;44(6):353-62. Epub 2007 Feb 27.
Title: Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).
Author: Vasen, H F A|Moslein, G|Alonso, A|Bernstein, I|Bertario, L|Blanco, I|Burn, J|Capella, G|Engel, C|Frayling, I|Friedl, W|Hes, F J|Hodgson, S|Mecklin, J-P|Moller, P|Nagengast, F|Parc, Y|Renkonen-Sinisalo, L|Sampson, J R|Stormorken, A|Wijnen, J
PMID: 17327285
Journal: Int J Colorectal Dis. 2007 Aug;22(8):875-9. Epub 2007 Mar 1.
Title: A novel MSH2 mutation in a Chinese family with hereditary non-polyposis colorectal cancer.
Author: Zheng, Duo|Li, Tiegang|Liu, Xiaoping|Hu, Weixin|Chen, Hanchun|Yang, Yongjia
PMID: 17333219
Journal: Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title: Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Suemoto, Yuko|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 17339237
Journal: Ann R Coll Surg Engl. 2007 Mar;89(2):127-9.
Title: Cancer genetics clinics and the surgeon: a valuable role for family history screening.
Author: Williams, G L|Gray, J|Beynon, J
PMID: 17346404
Journal: Hum Mutat. 2007 Jul;28(7):669-73.
Title: A new variant database for mismatch repair genes associated with Lynch syndrome.
Author: Woods, Michael O|Williams, Phillip|Careen, Amanda|Edwards, Laura|Bartlett, Sylvia|McLaughlin, John R|Younghusband, H Banfield
PMID: 17347989
Journal: Anticancer Res. 2007 Jan-Feb;27(1B):653-8.
Title: Nationwide study of clinical and molecular features of hereditary non-polyposis colorectal cancer (HNPCC) in Latvia.
Author: Irmejs, Arvids|Borosenko, Viktors|Melbarde-Gorkusa, Inga|Gardovskis, Andris|Bitina, Marianna|Kurzawski, Grzegorz|Suchy, Janina|Gorski, Bohdan|Gardovskis, Janis
PMID: 17348456
Journal: Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title: Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17350669
Journal: Eur J Cancer. 2007 Apr;43(6):1101-7. Epub 2007 Mar 12.
Title: Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer.
Author: Zlobec, Inti|Minoo, Parham|Baker, Kristi|Haegert, David|Khetani, Karim|Tornillo, Luigi|Terracciano, Luigi|Jass, Jeremy R|Lugli, Alessandro
PMID: 17350821
Journal: Hum Mol Genet. 2007 May 1;16(9):1072-7. Epub 2007 Mar 9.
Title: MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer.
Author: Hubner, Richard A|Lubbe, Steven|Chandler, Ian|Houlston, Richard S
PMID: 17350979
Journal: Bull Hist Med. 2007 Spring;81(1):267-85.
Title: From cancer families to HNPCC: Henry Lynch and the transformations of hereditary cancer, 1975-1999.
Author: Necochea, Raul
PMID: 17369671
Journal: Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.
Title: CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Author: Ogino, Shuji|Meyerhardt, Jeffrey A|Kawasaki, Takako|Clark, Jeffrey W|Ryan, David P|Kulke, Matthew H|Enzinger, Peter C|Wolpin, Brian M|Loda, Massimo|Fuchs, Charles S
PMID: 17372756
Journal: Int J Cancer. 2007 Jul 15;121(2):454-8.
Title: Beta2-microglobulin mutations in microsatellite unstable colorectal tumors.
Author: Kloor, Matthias|Michel, Sara|Buckowitz, Boris|Ruschoff, Josef|Buttner, Reinhard|Holinski-Feder, Elke|Dippold, Wolfgang|Wagner, Rudolf|Tariverdian, Mirjam|Benner, Axel|Schwitalle, Yvette|Kuchenbuch, Beate|von Knebel Doeberitz, Magnus
PMID: 17373663
Journal: J Natl Cancer Inst. 2007 Mar 21;99(6):463-74.
Title: MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.
Author: Raptis, Stavroula|Mrkonjic, Miralem|Green, Roger C|Pethe, Vaijayanti V|Monga, Neerav|Chan, Yuen Man|Daftary, Darshana|Dicks, Elizabeth|Younghusband, Banfield H|Parfrey, Patrick S|Gallinger, Steven S|McLaughlin, John R|Knight, Julia A|Bapat, Bharati
PMID: 17374836
Journal: Am J Gastroenterol. 2007 May;102(5):1070-6. Epub 2007 Mar 22.
Title: Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps.
Author: Leung, Wai K|To, Ka-Fai|Man, Ellen P S|Chan, Michael W Y|Hui, Aric J|Ng, Simon S M|Lau, James Y W|Sung, Joseph J Y
PMID: 17378912
Journal: Eur J Neurol. 2007 Apr;14(4):470-2.
Title: Turcot syndrome confirmed with molecular analysis.
Author: Lebrun, C|Olschwang, S|Jeannin, S|Vandenbos, F|Sobol, H|Frenay, M
PMID: 17389002
Journal: Keio J Med. 2007 Mar;56(1):14-20.
Title: Genetic testing in colorectal cancer: who, when, how and why.
Author: Davidson, Nicholas O
PMID: 17392593
Journal: Gastroenterology. 2007 Apr;132(4):1254-60. Epub 2007 Jan 25.
Title: Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.
Author: Konishi, Kazuo|Shen, Lanlan|Wang, Suna|Meltzer, Stephen J|Harpaz, Noam|Issa, Jean-Pierre J
PMID: 17408633
Journal: Gut. 2007 Sep;56(9):1198-201.
Title: Is surveillance of the small bowel indicated for Lynch syndrome families?
Author: ten Kate, G L|Kleibeuker, J H|Nagengast, F M|Craanen, M|Cats, A|Menko, F H|Vasen, H F A
PMID: 17409122
Journal: Ann Surg. 2007 Apr;245(4):560-5.
Title: Single-amplicon MSH2 A636P mutation testing in Ashkenazi Jewish patients with colorectal cancer: role in presurgical management.
Author: Guillem, Jose G|Glogowski, Emily|Moore, Harvey G|Nafa, Khedoudja|Markowitz, Arnold J|Shia, Jinru|Offit, Kenneth|Ellis, Nathan A
PMID: 17414604
Journal: Int J Cancer. 2007 Aug 1;121(3):555-8.
Title: Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.
Author: Schafmayer, Clemens|Buch, Stephan|Egberts, Jan Hendrik|Franke, Andre|Brosch, Mario|El Sharawy, Abdou|Conring, Mareike|Koschnick, Maralde|Schwiedernoch, Sven|Katalinic, Alexander|Kremer, Bernd|Folsch, Ulrich R|Krawczak, Michael|Fandrich, Fred|Schreiber, St
PMID: 17417778
Journal: J Pathol. 2007 Jun;212(2):124-33.
Title: Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis.
Author: Minoo, P|Moyer, M P|Jass, J R
PMID: 17427169
Journal: Br J Surg. 2007 Aug;94(8):1020-7.
Title: Immunohistochemical staining for mismatch repair proteins, and its relevance in the diagnosis of hereditary non-polyposis colorectal cancer.
Author: Ewald, J|Rodrigue, C M|Mourra, N|Lefevre, J H|Flejou, J-F|Tiret, E|Gespach, C|Parc, Y R
PMID: 17440950
Journal: Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1455-61.
Title: Prognostic and predictive value of baseline and posttreatment molecular marker expression in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.
Author: Bertolini, Federica|Bengala, Carmelo|Losi, Luisa|Pagano, Maria|Iachetta, Francesco|Dealis, Cristina|Jovic, Gordana|Depenni, Roberta|Zironi, Sandra|Falchi, Anna Maria|Luppi, Gabriele|Conte, Pier Franco
PMID: 17445998
Journal: Histopathology. 2007 Mar;50(4):453-64.
Title: Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis.
Author: Lugli, A|Zlobec, I|Minoo, P|Baker, K|Tornillo, L|Terracciano, L|Jass, J R
PMID: 17448021
Journal: Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21.
Title: Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.
Author: Curtin, Karen|Slattery, Martha L|Ulrich, Cornelia M|Bigler, Jeannette|Levin, Theodore R|Wolff, Roger K|Albertsen, Hans|Potter, John D|Samowitz, Wade S
PMID: 17449906
Journal: Orv Hetil. 2007 Apr 29;148(17):779-85.
Title: [Stem cell theory of colorectal cancer and its connection with molecular-biological data].
Author: Hagymasi, Krisztina|Molnar, Bela|Sipos, Ferenc|Galamb, Orsolya|Tulassay, Zsolt
PMID: 17452307
Journal: Fam Cancer. 2007;6(3):301-10. Epub 2007 Apr 24.
Title: Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer.
Author: Loughrey, M B|Waring, P M|Tan, A|Trivett, M|Kovalenko, S|Beshay, V|Young, M-A|McArthur, G|Boussioutas, A|Dobrovic, A
PMID: 17453358
Journal: Pathology. 2007 Apr;39(2):228-34.
Title: No difference in the occurrence of mismatch repair defects and APC and CTNNB1 genes mutation in a multi-racial colorectal carcinoma patient cohort.
Author: Tan, Lu Ping|Ng, Ban Kim|Balraj, Pauline|Lim, Patricia Kim Chooi|Peh, Suat Cheng
PMID: 17454753
Journal: Am J Surg Pathol. 2007 May;31(5):744-51.
Title: Utility of immunohistochemistry in predicting microsatellite instability in endometrial carcinoma.
Author: Modica, Ippolito|Soslow, Robert A|Black, Destin|Tornos, Carmen|Kauff, Noah|Shia, Jinru
PMID: 17460459
Journal: World J Gastroenterol. 2007 Mar 14;13(10):1612-7.
Title: Clinical and molecular analysis of hereditary non-polyposis colorectal cancer in Chinese colorectal cancer patients.
Author: Wang, Jun|Luo, Mao-Hong|Zhang, Zuo-Xing|Zhang, Pei-Da|Jiang, Xi-Li|Ma, Dong-Wang|Suo, Rong-Zeng|Zhao, Li-Zhong|Qi, Qing-Hui
PMID: 17461458
Journal: Anticancer Res. 2007 Mar-Apr;27(2):1151-6.
Title: Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16(INK4a), p4(ARF) and hMLH1.
Author: Mas, Sergi|Lafuente, M Jose|Crescenti, Anna|Trias, Manuel|Ballesta, Antonio|Molina, Rafael|Zheng, Shichun|Wiencke, John K|Lafuente, Amalia
PMID: 17465256
Journal: World J Gastroenterol. 2007 Mar 28;13(12):1767-9.
Title: Microsatellite instability and MLH1 promoter hypermethylation in colorectal cancer.
Author: Niv, Yaron
PMID: 17465465
Journal: Dis Colon Rectum. 2007 Jul;50(7):971-80.
Title: Detection of metachronous neoplasms in colorectal cancer patients: identification of risk factors.
Author: Balleste, Belen|Bessa, Xavier|Pinol, Virginia|Castellvi-Bel, Sergi|Castells, Antoni|Alenda, Cristina|Paya, Artemio|Jover, Rodrigo|Xicola, Rosa Ma|Pons, Elisenda|Llor, Xavier|Cordero, Carmen|Fernandez-Banares, Ferran|de Castro, Luisa|Rene, Josep Maria|Andr
PMID: 17468913
Journal: Dis Markers. 2007;23(3):179-87.
Title: A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.
Author: Pedroni, M|Roncari, B|Maffei, S|Losi, L|Scarselli, A|Di Gregorio, C|Marino, M|Roncucci, L|Benatti, P|Ponti, G|Rossi, G|Menigatti, M|Viel, A|Genuardi, M|de Leon, M Ponz
PMID: 17473388
Journal: Eur J Hum Genet. 2007 Aug;15(8):831-6. Epub 2007 May 2.
Title: Estimating cancer risk in HNPCC by the GRL method.
Author: Alarcon, Flora|Lasset, Christine|Carayol, Jerome|Bonadona, Valerie|Perdry, Herve|Desseigne, Francoise|Wang, Qing|Bonaiti-Pellie, Catherine
PMID: 17473834
Journal: BMC Cancer. 2007 May 2;7:72.
Title: 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Ohnishi, Mutsuko|Fuchs, Charles S
PMID: 17474983
Journal: PLoS One. 2007 May 2;2(5):e399.
Title: LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.
Author: Estecio, Marcos R H|Gharibyan, Vazganush|Shen, Lanlan|Ibrahim, Ashraf E K|Doshi, Ketan|He, Rong|Jelinek, Jaroslav|Yang, Allen S|Yan, Pearlly S|Huang, Tim H-M|Tajara, Eloiza H|Issa, Jean-Pierre J
PMID: 17476321
Journal: Clin Cancer Res. 2007 May 15;13(10):2865-9.
Title: Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genes.
Author: Mead, Leeanne J|Jenkins, Mark A|Young, Joanne|Royce, Simon G|Smith, Letitia|St John, D James B|Macrae, Finlay|Giles, Graham G|Hopper, John L|Southey, Melissa C
PMID: 17504984
Journal: Scand J Gastroenterol. 2007 Jun;42(6):746-53.
Title: Genotype-phenotype correlations in individuals with a founder mutation in the MLH1 gene and hereditary non-polyposis colorectal cancer.
Author: de Leon, Maurizio Ponz|Benatti, Piero|Di Gregorio, Carmela|Losi, Lorena|Pedroni, Monica|Ponti, Giovanni|Genuardi, Maurizio|Viel, Alessandra|Lucci-Cordisco, Emanuela|Rossi, Giuseppina|Roncucci, Luca
PMID: 17505997
Journal: J Cancer Res Clin Oncol. 2007 Oct;133(10):749-59. Epub 2007 May 25.
Title: Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression.
Author: Alldinger, I|Schaefer, K L|Goedde, D|Ottaviano, L|Dirksen, U|Ranft, A|Juergens, H|Gabbert, H E|Knoefel, W T|Poremba, C
PMID: 17530287
Journal: Clin Cancer Res. 2007 Jun 1;13(11):3221-8.
Title: Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR.
Author: Bettstetter, Marcus|Dechant, Stephan|Ruemmele, Petra|Grabowski, Monika|Keller, Gisela|Holinski-Feder, Elke|Hartmann, Arndt|Hofstaedter, Ferdinand|Dietmaier, Wolfgang
PMID: 17545526
Journal: Genetika. 2007 Apr;43(4):537-44.
Title: [Mismatch repair (MMR) efficiency and MSH2 gene mutation in human colorectal carcinoma cell line COLO320HSR].
Author: Tronov, V A|Kramarenko, I I|Maiorova, E N|Zakharov, S F
PMID: 17555131
Journal: World J Gastroenterol. 2007 May 21;13(19):2727-32.
Title: Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families: implications for genetic testing.
Author: Papp, Janos|Kovacs, Marietta E|Olah, Edith
PMID: 17569143
Journal: Cancer Lett. 2007 Oct 8;255(2):295-9. Epub 2007 Jun 19.
Title: High proportion of large genomic rearrangements in hMSH2 in hereditary nonpolyposis colorectal cancer (HNPCC) families of the Basque Country.
Author: Martinez-Bouzas, Cristina|Ojembarrena, Enrique|Beristain, Elena|Errasti, Javier|Viguera, Noelia|Tejada Minguez, Maria-Isabel
PMID: 17582678
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jun;27(6):779-82.
Title: [Microsatellite analysis and hMLH1/hMSH2 expression detection in young patients with colorectal cancer: value in screening hereditary nonpolyposis colorectal cancer].
Author: Yang, Lei|Ding, Yan-qing|Li, Guo-xin|Yu, Jiang|Wang, Yu|Zhou, Jun|Yang, Hong-jun|Zhang, Jin-hua
PMID: 17584637
Journal: J Mol Diagn. 2007 Jul;9(3):305-14.
Title: Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Kraft, Peter|Loda, Massimo|Fuchs, Charles S
PMID: 17591929
Journal: Clin Cancer Res. 2007 Jul 1;13(13):3831-9.
Title: Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer.
Author: Malesci, Alberto|Laghi, Luigi|Bianchi, Paolo|Delconte, Gabriele|Randolph, Ann|Torri, Valter|Carnaghi, Carlo|Doci, Roberto|Rosati, Riccardo|Montorsi, Marco|Roncalli, Massimo|Gennari, Leandro|Santoro, Armando
PMID: 17606714
Journal: World J Surg Oncol. 2007 Jul 4;5:73.
Title: Surgical outcomes for colon and rectal cancer over a decade: results from a consecutive monocentric experience in 902 unselected patients.
Author: Andreoni, Bruno|Chiappa, Antonio|Bertani, Emilio|Bellomi, Massimo|Orecchia, Roberto|Zampino, Mariagiulia|Fazio, Nicola|Venturino, Marco|Orsi, Franco|Sonzogni, Angelica|Pace, Ugo|Monfardini, Lorenzo
PMID: 17610720
Journal: Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R14-20.
Title: TGF-beta signaling alterations and susceptibility to colorectal cancer.
Author: Xu, Yanfei|Pasche, Boris
PMID: 17613544
Journal: Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R60-6.
Title: Cancer genes associated with phenotypes in monoallelic and biallelic mutation carriers: new lessons from old players.
Author: Rahman, Nazneen|Scott, Richard H
PMID: 17613548
Journal: Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title: MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author: Ogino, Shuji|Hazra, Aditi|Tranah, Gregory J|Kirkner, Gregory J|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Meyerhardt, Jeffrey A|Hunter, David J|Fuchs, Charles S
PMID: 17621591
Journal: Clin J Oncol Nurs. 2007 Jun;11(3):423-7.
Title: Understanding Lynch syndrome: implications for nursing.
Author: Bannon, Eileen|Coleman, Elizabeth Ann
PMID: 17623626
Journal: Cancer Causes Control. 2007 Oct;18(8):865-79. Epub 2007 Jul 18.
Title: Dietary fat and risk of colon and rectal cancer with aberrant MLH1 expression, APC or KRAS genes.
Author: Weijenberg, Matty P|Luchtenborg, Margreet|de Goeij, Anton F P M|Brink, Mirian|van Muijen, Goos N P|de Bruine, Adriaan P|Goldbohm, R Alexandra|van den Brandt, Piet A
PMID: 17636402
Journal: Cancer Sci. 2007 Sep;98(9):1454-60.
Title: Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa.
Author: Iacopetta, Barry|Grieu, Fabienne|Phillips, Michael|Ruszkiewicz, Andrew|Moore, James|Minamoto, Toshinari|Kawakami, Kazuyuki
PMID: 17640302
Journal: J Mol Diagn. 2007 Sep;9(4):472-8. Epub 2007 Jul 25.
Title: Heterogeneous staining for mismatch repair proteins during population-based prescreening for hereditary nonpolyposis colorectal cancer.
Author: Watson, Natasha|Grieu, Fabienne|Morris, Melinda|Harvey, Jennet|Stewart, Colin|Schofield, Lyn|Goldblatt, Jack|Iacopetta, Barry
PMID: 17652638
Journal: Obstet Gynecol. 2007 Aug;110(2 Pt 2):543-5.
Title: Uterine carcinosarcoma associated with hereditary nonpolyposis colorectal cancer.
Author: South, Stacey A|Hutton, Mollie|Farrell, Carolyn|Mhawech-Fauceglia, Paulette|Rodabaugh, Kerry J
PMID: 17666659
Journal: Neoplasma. 2007;54(5):391-401.
Title: The role of clinical criteria, genetic and epigenetic alterations in Lynch-syndrome diagnosis.
Author: Alemayehu, A|Tomkova, K|Zavodna, K|Ventusova, K|Krivulcik, T|Bujalkova, M|Bartosova, Z|Fridrichova, I
PMID: 17688369
Journal: Biochem Genet. 2007 Oct;45(9-10):671-81.
Title: A single nucleotide substitution (-107C-->G) in the hMLH1 promoter found in colorectal cancer population reduces transcriptional activity.
Author: Zhong, Xiaoling|Arita, Michitsune|Yamada, Kanae|Sugiyama, Hisahiko|Tan, Ke|Kanazawa, Shinsaku|Koike, Junichi|Teramoto, Tatsuo|Hemmi, Hiromichi
PMID: 17690979
Journal: Neoplasia. 2007 Jul;9(7):569-77.
Title: Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Dehari, Reiko|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 17710160
Journal: Eur J Gynaecol Oncol. 2007;28(4):319-21.
Title: Rectal carcinoma after radiotherapy for cervical carcinoma in patients with a family history of colorectal carcinoma: report of two cases.
Author: Melichar, B|Ryska, A|Krepelova, A|Holeckova, P
PMID: 17713103
Journal: Tumour Biol. 2007;28(4):212-20.
Title: Mismatch repair status is a predictive factor of tumour response to 5-fluorouracil and irinotecan chemotherapy in patients with advanced colorectal cancer.
Author: Bendardaf, R|Lamlum, H|Ristamaki, R|Korkeila, E|Syrjanen, K|Pyrhonen, S
PMID: 17717427
Journal: World J Gastroenterol. 2007 Sep 7;13(33):4437-44.
Title: Importance of MutL homologue MLH1 and MutS homologue MSH2 expression in Turkish patients with sporadic colorectal cancer.
Author: Erdamar, Sibel|Ucaryilmaz, Esra|Demir, Gokhan|Karahasanoglu, Tayfun|Dogusoy, Gulen|Dirican, Ahmet|Goksel, Suha
PMID: 17724798
Journal: Cell Oncol. 2007;29(5):409-19.
Title: Independent induction of caspase-8 and cFLIP expression during colorectal carcinogenesis in sporadic and HNPCC adenomas and carcinomas.
Author: Heijink, D M|Kleibeuker, J H|Jalving, M|Boersma-van Ek, W|Koornstra, J J|Wesseling, J|de Jong, S
PMID: 17726263
Journal: Evid Rep Technol Assess (Full Rep). 2007 May;(150):1-180.
Title: Hereditary nonpolyposis colorectal cancer: diagnostic strategies and their implications.
Author: Bonis, Peter A|Trikalinos, Thomas A|Chung, Mei|Chew, Priscilla|Ip, Stanley|DeVine, Deirdre A|Lau, Joseph
PMID: 17764220
Journal: Zhonghua Yi Xue Za Zhi. 2007 Jun 5;87(21):1445-7.
Title: [Screening the hereditary nonpolyposis colorectal cancer by revised Bethesda guideline: a cohort study of 110 cases].
Author: Jin, Hei-Ying|Ding, Yi-Jiang|Liu, Xiu-Fang|Yang, Bo-Lin|Lai, Ren-Sheng|Ni, Min|Ge, Yong-Sheng
PMID: 17785078
Journal: Harefuah. 2007 Jul;146(7):510-4, 576, 575.
Title: [A new oncogenetic service of counseling and diagnosing for hereditary non-polyposis colorectal cancer (HNPCC)].
Author: Goldberg, Yael|Porat, Rinnat|Sagi, Michal|Eilat, Avital|Kedar, Inbal|Shochat, Chen|Mendelson, Suzan|Hamburger, Tamar|Nissan, Aviram|Hubert, Ayala|Shalev, Stavit|Bercovich, Dani|Pikarski, Eli|Lerer, Israela|Abeliovich, Dvorah|Pretetz, Tamar
PMID: 17803162
Journal: World J Gastroenterol. 2007 Oct 7;13(37):5021-4.
Title: Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families.
Author: Yan, Shi-Yan|Zhou, Xiao-Yan|Du, Xiang|Zhang, Tai-Ming|Lu, Yong-Ming|Cai, San-Jun|Xu, Xiao-Li|Yu, Bao-Hua|Zhou, Heng-Hua|Shi, Da-Ren
PMID: 17854147
Journal: Clin Genet. 2007 Dec;72(6):556-61.
Title: Germline hMSH2 promoter mutation in a Chinese HNPCC kindred: evidence for dual role of LOH.
Author: Yan, H|Jin, H|Xue, G|Mei, Q|Ding, F|Hao, L|Sun, S-H
PMID: 17894833
Journal: J Natl Cancer Inst. 2007 Oct 3;99(19):1490; author reply 1490-1. Epub 2007 Sep
Title: Re: MLH1 93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.
Author: Hubner, Richard A|Houlston, Richard S
PMID: 17895478
Journal: Am J Clin Dermatol. 2007;8(5):315-9.
Title: Muir-Torre syndrome.
Author: Lachiewicz, Anne M|Wilkinson, Todd M|Groben, Pamela|Ollila, David W|Thomas, Nancy E
PMID: 17902735
Journal: Cancer Res. 2007 Oct 1;67(19):9107-16.
Title: Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.
Author: Hitchins, Megan P|Lin, Vita Ap|Buckle, Andrew|Cheong, Kayfong|Halani, Nimita|Ku, Su|Kwok, Chau-To|Packham, Deborah|Suter, Catherine M|Meagher, Alan|Stirzaker, Clare|Clark, Susan|Hawkins, Nicholas J|Ward, Robyn L
PMID: 17909015
Journal: Oncol Rep. 2007 Nov;18(5):1093-7.
Title: Involvement of the serrated neoplasia pathway in inflammatory bowel disease-related colorectal oncogenesis.
Author: Bossard, Celine|Denis, Marc G|Bezieau, Stephane|Bach-Ngohou, Kalyane|Bourreille, Arnaud|Laboisse, Christian L|Mosnier, Jean-Francois
PMID: 17914558
Journal: Oncol Rep. 2007 Nov;18(5):1129-37.
Title: Decreased expression of hMLH1 correlates with reduced 5-fluorouracil-mediated apoptosis in colon cancer cells.
Author: Fujita, Hideyuki|Kato, Jun|Horii, Joichiro|Harada, Keita|Hiraoka, Sakiko|Shiraha, Hidenori|Sakaguchi, Kohsaku|Shiratori, Yasushi
PMID: 17914563
Journal: Semin Oncol. 2007 Oct;34(5):425-7.
Title: Familial colorectal cancer syndrome X.
Author: Lipkin, Steven M|Afrasiabi, Kambiz
PMID: 17920898
Journal: Am J Clin Nutr. 2007 Oct;86(4):1064-72.
Title: Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia.
Author: Al-Ghnaniem, Reyad|Peters, Jennifer|Foresti, Roberta|Heaton, Nigel|Pufulete, Maria
PMID: 17921385
Journal: J Korean Med Sci. 2007 Sep;22 Suppl:S91-7.
Title: Clinicopathological characteristics of colorectal cancer with family history: an evaluation of family history as a predictive factor for microsatellite instability.
Author: Park, In Ja|Kim, Hee Cheol|Yoon, Yong Sik|Yu, Chang Sik|Jang, Se Jin|Kim, Jin Cheon
PMID: 17923762
Journal: J Clin Oncol. 2007 Nov 20;25(33):5158-64. Epub 2007 Oct 9.
Title: Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer.
Author: Lu, Karen H|Schorge, John O|Rodabaugh, Kerry J|Daniels, Molly S|Sun, Charlotte C|Soliman, Pamela T|White, Kristin G|Luthra, Rajyalakshmi|Gershenson, David M|Broaddus, Russell R
PMID: 17925543
Journal: Clin Cancer Res. 2007 Oct 15;13(20):6093-8.
Title: Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.
Author: Shen, Lanlan|Catalano, Paul J|Benson, Al B 3rd|O'Dwyer, Peter|Hamilton, Stanley R|Issa, Jean-Pierre J
PMID: 17947473
Journal: Digestion. 2007;76(1):68-76. Epub 2007 Oct 19.
Title: Prevention of colorectal cancer in high-risk populations: the increasing role for endoscopy and chemoprevention in FAP and HNPCC.
Author: Lynch, Patrick M
PMID: 17947820
Journal: Stat Med. 2007 Dec 30;26(30):5545-56.
Title: Data reduction for prediction: a case study on robust coding of age and family history for the risk of having a genetic mutation.
Author: Steyerberg, Ewout W|Balmana, Judith|Stockwell, David H|Syngal, Sapna
PMID: 17948867
Journal: Genet Test. 2007 Fall;11(3):315-20.
Title: Similar colorectal cancer risk in patients with monoallelic and biallelic mutations in the MYH gene identified in a population with adenomatous polyposis.
Author: Olschwang, Sylviane|Blanche, Helene|de Moncuit, Celine|Thomas, Gilles
PMID: 17949294
Journal: Gynecol Oncol. 2007 Nov;107(2):159-62.
Title: Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions.
Author: Lancaster, Johnathan M|Powell, C Bethan|Kauff, Noah D|Cass, Ilana|Chen, Lee-May|Lu, Karen H|Mutch, David G|Berchuck, Andrew|Karlan, Beth Y|Herzog, Thomas J
PMID: 17950381
Journal: Tumour Biol. 2007;28(5):290-300. Epub 2007 Oct 26.
Title: Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time?
Author: Soreide, Kjetil
PMID: 17962726
Journal: Cancer Biol Ther. 2007 Nov;6(11):1710-6. Epub 2007 Aug 3.
Title: Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer.
Author: Riojas, Marco A|Guo, Mingzhou|Glockner, Sabine C|Machida, Emi Ota|Baylin, Stephen B|Ahuja, Nita
PMID: 17986858
Journal: Cytogenet Genome Res. 2007;118(2-4):214-21.
Title: SNP-Array genotyping and spectral karyotyping reveal uniparental disomy as early mutational event in MSS- and MSI-colorectal cancer cell lines.
Author: Melcher, R|Al-Taie, O|Kudlich, T|Hartmann, E|Maisch, S|Steinlein, C|Schmid, M|Rosenwald, A|Menzel, T|Scheppach, W|Luhrs, H
PMID: 18000373
Journal: Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2344-50.
Title: Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people.
Author: Boardman, Lisa A|Lanier, Anne P|French, Amy J|Schowalter, Karen V|Burgart, Lawrence J|Koller, Kathryn R|McDonnell, Shannon K|Schaid, Daniel J|Thibodeau, Stephen N
PMID: 18006922
Journal: J Nutr. 2007 Dec;137(12):2622-8.
Title: Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells.
Author: Fini, Lucia|Selgrad, Michael|Fogliano, Vincenzo|Graziani, Giulia|Romano, Marco|Hotchkiss, Erin|Daoud, Yahya A|De Vol, Edward B|Boland, C Richard|Ricciardiello, Luigi
PMID: 18029474
Journal: Biochem Soc Trans. 2007 Dec;35(Pt 6):1525-8.
Title: Humanizing mismatch repair in yeast: towards effective identification of hereditary non-polyposis colorectal cancer alleles.
Author: Aldred, P M R|Borts, R H
PMID: 18031259
Journal: World J Gastroenterol. 2007 Dec 14;13(46):6254-8.
Title: Two novel germline mutations of MLH1 and investigation of their pathobiology in hereditary non-polyposis colorectal cancer families in China.
Author: Wang, Chao-Fu|Zhou, Xiao-Yan|Zhang, Tai-Ming|Xu, Ye|Cai, San-Jun|Shi, Da-Ren
PMID: 18069769
Journal: Neoplasia. 2007 Dec;9(12):1091-8.
Title: IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 18084616
Journal: Anticancer Res. 2007 Nov-Dec;27(6C):4465-71.
Title: hMLH1, hMSH2 and cyclooxygenase-2 (cox-2) in sporadic colorectal polyps.
Author: Balbinotti, Raul Angelo|Ribeiro, Ulysses Jr|Sakai, Paulo|Safatle-Ribeiro, Adriana Vaz|Balbinotti, Silvana Sartori|Scapulatempo, Cristovam|Alves, Venancio Avancini Ferreira|Corbett, Carlos Eduardo Pereira|Carrilho, Flair Jose
PMID: 18214062
Journal: Anticancer Res. 2007 Nov-Dec;27(6B):3807-12.
Title: Piroxicam increases colon tumorigenesis and promotes apoptosis in Mlh1 +/- /Apc1638(N/+) mice.
Author: Palmerini, Emanuela|Fan, Kunhua|Yang, Kan|Risio, Mauro|Edelmann, Winfried|Lipkin, Martin|Biasco, Guido
PMID: 18225536
Journal: Hepatogastroenterology. 2007 Dec;54(80):2410-4.
Title: MSI is frequently recognized among gastric cancer patients with a family history of cancer.
Author: Kanemitsu, Kiyonori|Kawasaki, Kentaro|Nakamura, Mitsutoshi|Li, Dong|Yasuda, Takashi|Kuroda, Daisuke|Yokozaki, Hiroshi|Kamigaki, Takashi|Kuroda, Yoshikazu
PMID: 18265677
Journal: Verh Dtsch Ges Pathol. 2007;91:119-25.
Title: [Colorectal serrated adenoma: diagnostic criteria and clinical implications].
Author: Ruschoff, J|Aust, D|Hartmann, A
PMID: 18314605
Journal: Acta Med Port. 2007 Nov-Dec;20(6):535-42. Epub 2008 Feb 13.
Title: [Need of new clinical criteria for the identification of genetic Lynch syndrome].
Author: Sousa, Rita|Lage, Pedro|Ferreira, Sara|Claro, Isabel|Francisco, Ines|Filipe, Bruno|Albuquerque, Cristina|Suspiro, Alexandra|Rodrigues, Paula|Nobre-Leitao, Carlos
PMID: 18331697
Journal: J Exp Clin Cancer Res. 2007 Dec;26(4):521-6.
Title: Promoter hypermethylation of tumor-related genes in sporadic colorectal cancer in young patients.
Author: Noda, H|Mashima, R|Kamiyama, H|Okada, S|Kawamura, Y J|Konishi, F
PMID: 18365548
Journal: Ann Pathol. 2007 Dec;27(6):433-8.
Title: [How and when to search for microsatellite instability in colorectal cancer in 2008?].
Author: Paraf, Francois
PMID: 18554553
Journal: Gut Liver. 2007 Jun;1(1):1-11.
Title: Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia.
Author: Kim, Young S|Deng, Guoren
PMID: 20485652
Journal: Int J Gynecol Cancer. 2008 Jan-Feb;18(1):136-40. Epub 2007 Apr 26.
Title: Correlation between patient weight and defects in DNA mismatch repair: is this the link between an increased risk of previous cancer in thinner women with endometrial cancer?
Author: Cohn, D E|Pavelka, J C|Frankel, W L|Morrison, C D|Hampel, H|Copeland, L J|Fowler, J M
PMID: 17466051
Journal: Fam Cancer. 2008;7(1):15-26. Epub 2007 Jun 13.
Title: Pathology of the hereditary colorectal carcinoma.
Author: Gatalica, Zoran|Torlakovic, Emina
PMID: 17564815
Journal: Fam Cancer. 2008;7(2):135-9. Epub 2007 Jul 29.
Title: A novel MSH2 germline mutation in a Druze HNPCC family.
Author: Zidan, Jamal|Niessen, Renee C|Laitman, Yael|Rozeveld, Dennie|Hofstra, Robert M W|Friedman, Eitan
PMID: 17661183
Journal: Eur J Hum Genet. 2008 Jan;16(1):62-72. Epub 2007 Sep 12.
Title: Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1.
Author: Kruger, Stefan|Kinzel, Miriam|Walldorf, Constanze|Gottschling, Sven|Bier, Andrea|Tinschert, Sigrid|von Stackelberg, Arend|Henn, Wolfram|Gorgens, Heike|Boue, Stephanie|Kolble, Konrad|Buttner, Reinhard|Schackert, Hans K
PMID: 17851451
Journal: Colorectal Dis. 2008 Jun;10(5):490-7.
Title: Strategy in clinical practice for classification of unselected colorectal tumours based on mismatch repair deficiency.
Author: Jensen, L H|Lindebjerg, J|Byriel, L|Kolvraa, S|Cruger, D G
PMID: 17868408
Journal: Fam Cancer. 2008;7(2):157-62. Epub 2007 Oct 10.
Title: Sessile serrated polyps of the colorectum are rare in patients with Lynch syndrome and in familial colorectal cancer families.
Author: Andersen, S H|Lykke, E|Folker, M B|Bernstein, I|Holck, S
PMID: 17929199
Journal: Fam Cancer. 2008;7(2):163-72. Epub 2007 Oct 16.
Title: Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC).
Author: Geary, Johanne|Sasieni, Peter|Houlston, Richard|Izatt, Louise|Eeles, Ros|Payne, Stewart J|Fisher, Samantha|Hodgson, Shirley V
PMID: 17939062
Journal: Acta Oncol. 2008;47(6):1046-53.
Title: Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.
Author: Bendardaf, R|Lamlum, H|Ristamaki, R|Korkeila, E|Syrjanen, K|Pyrhonen, S
PMID: 17943475
Journal: Gynecol Oncol. 2008 Feb;108(2):438-44. Epub 2007 Nov 26.
Title: Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair.
Author: Case, Ashley S|Zighelboim, Israel|Mutch, David G|Babb, Sheri A|Schmidt, Amy P|Whelan, Alison J|Thibodeau, Stephen N|Goodfellow, Paul J
PMID: 18022218
Journal: Int J Cancer. 2008 Mar 15;122(6):1273-7.
Title: Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.
Author: Talseth, Bente A|Ashton, Katie A|Meldrum, Cliff|Suchy, Janina|Kurzawski, Grzegorz|Lubinski, Jan|Scott, Rodney J
PMID: 18027856
Journal: Hum Mutat. 2008 Mar;29(3):367-74.
Title: Classification of ambiguous mutations in DNA mismatch repair genes identified in a population-based study of colorectal cancer.
Author: Barnetson, Rebecca A|Cartwright, Nicola|van Vliet, Annelot|Haq, Naila|Drew, Kate|Farrington, Susan|Williams, Nicola|Warner, Jon|Campbell, Harry|Porteous, Mary E|Dunlop, Malcolm G
PMID: 18033691
Journal: Carcinogenesis. 2008 Feb;29(2):434-9.
Title: Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Author: Derks, Sarah|Postma, Cindy|Carvalho, Beatriz|van den Bosch, Sandra M|Moerkerk, Peter T M|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon
PMID: 18048385
Journal: Fam Cancer. 2008;7(3):191-8.
Title: The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation.
Author: Blokhuis, Maria M|Goldberg, Paul A|Pietersen, G Elize|Algar, Ursula|Vorster, A Alvera|Govender, Dhiren|Ramesar, Raj S
PMID: 18049911
Journal: Gastroenterology. 2008 Jan;134(1):39-46. Epub 2007 Oct 26.
Title: Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients.
Author: Balaguer, Francesc|Balmana, Judith|Castellvi-Bel, Sergi|Steyerberg, Ewout W|Andreu, Montserrat|Llor, Xavier|Jover, Rodrigo|Syngal, Sapna|Castells, Antoni
PMID: 18061181
Journal: Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title: WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Liu, Zhiqian|Yamamoto, Hiroyuki|Loda, Massimo|Fuchs, Charles S|Ogino, Shuji
PMID: 18084250
Journal: Clin Gastroenterol Hepatol. 2008 Feb;6(2):206-14. Epub 2007 Dec 21.
Title: A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening.
Author: Bessa, Xavier|Balleste, Belen|Andreu, Montserrat|Castells, Antoni|Bellosillo, Beatriz|Balaguer, Francesc|Castellvi-Bel, Sergi|Paya, Artemio|Jover, Rodrigo|Alenda, Cristina|Tito, Llucia|Martinez-Villacampa, Mercedes|Vilella, Angels|Xicola, Rosa M|Pons, Eli
PMID: 18096441
Journal: Oncol Rep. 2008 Jan;19(1):41-7.
Title: Fhit, Mlh1, P53 and phenotypic expression in the early stage of colorectal neoplasms.
Author: Yasugi, Akiko|Yashima, Kazuo|Hara, Akihito|Koda, Masaharu|Kawaguchi, Koichiro|Harada, Kenichi|Andachi, Hironobu|Murawaki, Yoshikazu
PMID: 18097574
Journal: DNA Repair (Amst). 2008 Feb 1;7(2):321-8. Epub 2007 Dec 26.
Title: Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells.
Author: Abdel-Rahman, Wael M|Knuutila, Sakari|Peltomaki, Paivi|Harrison, David J|Bader, Scott A
PMID: 18162445
Journal: Fam Cancer. 2008;7(4):281-5.
Title: Working through a diagnostic challenge: colonic polyposis, Amsterdam criteria, and a mismatch repair mutation.
Author: Jasperson, Kory W|Blazer, Kathleen R|Lowstuter, Katrina|Weitzel, Jeffrey N
PMID: 18176851
Journal: World J Gastroenterol. 2008 Jan 14;14(2):298-302.
Title: Detection of hMSH2 and hMLH1 mutations in Chinese hereditary non-polyposis colorectal cancer kindreds.
Author: Zhang, Chang-Hua|He, Yu-Long|Wang, Fang-Jin|Song, Wu|Yuan, Xi-Yu|Yang, Dong-Jie|Chen, Chuang-Qi|Cai, Shi-Rong|Zhan, Wen-Hua
PMID: 18186571
Journal: Mod Pathol. 2008 Mar;21(3):245-55.
Title: CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Nosho, Katsuhiko|Suemoto, Yuko|Kirkner, Gregory J|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 18204436
Journal: Bull Cancer. 2008 Jan;95(1):121-32.
Title: [Clinical and molecular consequences of microsatellite instability in human cancers].
Author: Hamelin, Richard|Chalastanis, Alexandra|Colas, Chrystelle|El Bchiri, Jamila|Mercier, Dominique|Schreurs, Ann-Sofie|Simon, Virginie|Svrcek, Magali|Zaanan, Aziz|Borie, Claire|Buhard, Olivier|Capel, Emilie|Zouali, Habib|Praz, Francoise|Muleris, Martine|Flejo
PMID: 18230578
Journal: BMC Genomics. 2008 Jan 31;9:59.
Title: A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray.
Author: Zhang, Dingdong|Wang, Yan|Bai, Yunfei|Ge, Qinyu|Qiao, Yingjuan|Luo, Junfeng|Jia, Chao|Lu, Zuhong
PMID: 18237388
Journal: BMC Cancer. 2008 Feb 7;8:44.
Title: Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer.
Author: Jin, Hei-Ying|Liu, Xiufang|Li, Vicky Ka Ming|Ding, Yijiang|Yang, Bolin|Geng, Jianxiang|Lai, Rensheng|Ding, Shuqing|Ni, Min|Zhao, Ronghua
PMID: 18257912
Journal: J Mol Diagn. 2008 Mar;10(2):154-9.
Title: Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.
Author: Deschoolmeester, Vanessa|Baay, Marc|Wuyts, Wim|Van Marck, Eric|Van Damme, Nancy|Vermeulen, Peter|Lukaszuk, Krzysztof|Lardon, Filip|Vermorken, Jan B
PMID: 18258928
Journal: Cancer Sci. 2008 Feb;99(2):253-9.
Title: Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy.
Author: Saito, Kana|Sakurai, Shinji|Sano, Takaaki|Sakamoto, Kazuha|Asao, Takayuki|Hosoya, Yoshinori|Nakajima, Takashi|Kuwano, Hiroyuki
PMID: 18271923
Journal: Fam Cancer. 2008;7(3):267-74.
Title: Tumor histology helps to identify Lynch syndrome among colorectal cancer patients.
Author: Truta, Brindusa|Chen, Yunn-Yi|Blanco, Amie M|Deng, Guoren|Conrad, Peggy G|Kim, Yong Ho|Park, Eun Taek|Kakar, Sanjay|Kim, Young S|Velayos, Fernando|Sleisenger, Marvin H|Terdiman, Jonathan P
PMID: 18283560
Journal: Dig Dis Sci. 2008 Oct;53(10):2723-31.
Title: Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects.
Author: Ashktorab, Hassan|Brim, Hassan|Al-Riyami, Marwa|Date, Anand|Al-Mawaly, Kamla|Kashoub, Masoud|Al-Mjeni, Rayhaneh|Smoot, Duane T|Al-Moundhri, Mansoor|Al-Hashemi, Suleiman|Ganguly, Shyam S|Raeburn, Sandy
PMID: 18299982
Journal: Eur J Hum Genet. 2008 May;16(5):587-92.
Title: No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients.
Author: Steinke, Verena|Rahner, Nils|Morak, Monika|Keller, Gisela|Schackert, Hans K|Gorgens, Heike|Schmiegel, Wolff|Royer-Pokora, Brigitte|Dietmaier, Wolfgang|Kloor, Matthias|Engel, Christoph|Propping, Peter|Aretz, Stefan
PMID: 18301448
Journal: Ann Surg Oncol. 2008 May;15(5):1429-39.
Title: Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features.
Author: Leopoldo, Sarli|Lorena, Bottarelli|Cinzia, Azzoni|Gabriella, Di Cola|Angela Luciana, Barilli|Renato, Costi|Antonio, Mazzeo|Carlo, Salvemini|Cristina, Porrini|Stefano, Cecchini|Maurizio, Taglia|Luigi, Roncoroni|Cesare, Bordi
PMID: 18301950
Journal: Cancer Sci. 2008 Apr;99(4):770-80.
Title: Clinical features and mismatch repair genes analyses of Chinese suspected hereditary non-polyposis colorectal cancer: a cost-effective screening strategy proposal.
Author: Yan, Hong-Li|Hao, Li-Qiang|Jin, Hei-Ying|Xing, Qing-He|Xue, Geng|Mei, Qian|He, Jin|He, Lin|Sun, Shu-Han
PMID: 18307539
Journal: J Oral Pathol Med. 2008 Oct;37(9):543-8.
Title: Immunoexpression of hMSH2 and hMLH1 in oral squamous cell carcinoma and its relationship to histological grades of malignancy.
Author: Fernandes, Anacelia Mendes|Ramos-Jorge, Maria Leticia|Cardoso, Sergio Vitorino|Loyola, Adriano Mota|Mesquita, Ricardo Alves|Aguiar, Maria Cassia Ferreira
PMID: 18331286
Journal: Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4247-52.
Title: Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.
Author: Avdievich, Elena|Reiss, Cora|Scherer, Stefan J|Zhang, Yongwei|Maier, Sandra M|Jin, Bo|Hou, Harry Jr|Rosenwald, Andreas|Riedmiller, Hubertus|Kucherlapati, Raju|Cohen, Paula E|Edelmann, Winfried|Kneitz, Burkhard
PMID: 18337503
Journal: Carcinogenesis. 2008 Sep;29(9):1765-73.
Title: Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer.
Author: de Vogel, Stefan|Bongaerts, Brenda W C|Wouters, Kim A D|Kester, Arnold D M|Schouten, Leo J|de Goeij, Anton F P M|de Bruine, Adriaan P|Goldbohm, R Alexandra|van den Brandt, Piet A|van Engeland, Manon|Weijenberg, Matty P
PMID: 18339680
Journal: Gut. 2008 Aug;57(8):1097-101.
Title: Common variants in mismatch repair genes and risk of colorectal cancer.
Author: Koessler, T|Oestergaard, M Z|Song, H|Tyrer, J|Perkins, B|Dunning, A M|Easton, D F|Pharoah, P D P
PMID: 18364438
Journal: Int J Cancer. 2008 Jun 15;122(12):2767-73.
Title: LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S
PMID: 18366060
Journal: Cancer Res. 2008 Apr 1;68(7):2384-90.
Title: Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Author: Zeng, Xuehuo|Kinsella, Timothy J
PMID: 18381446
Journal: Genes Chromosomes Cancer. 2008 Jul;47(7):614-24.
Title: Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma.
Author: Castiglia, Daniele|Bernardini, Silvia|Alvino, Ester|Pagani, Elena|De Luca, Naomi|Falcinelli, Sabrina|Pacchiarotti, Alberto|Bonmassar, Enzo|Zambruno, Giovanna|D'Atri, Stefania
PMID: 18384130
Journal: Fam Cancer. 2008;7(4):303-7.
Title: Screening for urinary tract cancer with urine cytology in Lynch syndrome and familial colorectal cancer.
Author: Myrhoj, T|Andersen, M-B|Bernstein, I
PMID: 18389386
Journal: Fam Cancer. 2008;7(4):309-17.
Title: Mutation spectrum in HNPCC in the Israeli population.
Author: Goldberg, Yael|Porat, Rinnat M|Kedar, Inbal|Shochat, Chen|Sagi, Michal|Eilat, Avital|Mendelson, Suzan|Hamburger, Tamar|Nissan, Aviram|Hubert, Ayala|Kadouri, Luna|Pikarski, Eli|Lerer, Israela|Abeliovich, Dvorah|Bercovich, Dani|Peretz, Tamar
PMID: 18389388
Journal: Int J Cancer. 2008 Jul 15;123(2):444-449.
Title: The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome.
Author: Watson, Patrice|Vasen, Hans F A|Mecklin, Jukka-Pekka|Bernstein, Inge|Aarnio, Markku|Jarvinen, Heikki J|Myrhoj, Torben|Sunde, Lone|Wijnen, Juul T|Lynch, Henry T
PMID: 18398828
Journal: Mol Cancer Res. 2008 Apr;6(4):585-91.
Title: The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.
Author: Karpinski, Pawel|Ramsey, David|Grzebieniak, Zygmunt|Sasiadek, Maria M|Blin, Nikolaus
PMID: 18403637
Journal: Cancer Genet Cytogenet. 2008 Apr 15;182(2):136-9.
Title: A novel missense MSH2 gene mutation in a patient of a Korean family with hereditary nonpolyposis colorectal cancer.
Author: Park, Seo-Jin|Lee, Kyung-A|Park, Tae Sung|Kim, Nam Kyu|Song, Jaewoo|Kim, Bo-Young|Choi, Jong Rak
PMID: 18406877
Journal: Am J Med Genet A. 2008 May 15;146A(10):1314-9.
Title: Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus.
Author: Rahner, Nils|Hoefler, Gerald|Hogenauer, Christoph|Lackner, Caroline|Steinke, Verena|Sengteller, Marlies|Friedl, Waltraut|Aretz, Stefan|Propping, Peter|Mangold, Elisabeth|Walldorf, Constanze
PMID: 18409202
Journal: Fam Cancer. 2008;7(4):319-30.
Title: Genome-wide copy neutral LOH is infrequent in familial and sporadic microsatellite unstable carcinomas.
Author: van Puijenbroek, Marjo|Middeldorp, Anneke|Tops, Carli M J|van Eijk, Ronald|van der Klift, Heleen M|Vasen, Hans F A|Wijnen, Juul Th|Hes, Frederik J|Oosting, Jan|van Wezel, Tom|Morreau, Hans
PMID: 18415027
Journal: Gastroenterology. 2008 Jun;134(7):1950-60, 1960.e1.
Title: Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.
Author: Nagasaka, Takeshi|Koi, Minoru|Kloor, Matthias|Gebert, Johannes|Vilkin, Alex|Nishida, Naoshi|Shin, Sung Kwan|Sasamoto, Hiromi|Tanaka, Noriaki|Matsubara, Nagahide|Boland, C Richard|Goel, Ajay
PMID: 18435933
Journal: J Korean Med Sci. 2008 Apr;23(2):270-7.
Title: CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria.
Author: Kim, Hee Cheol|Lee, Hyeon Jung|Roh, Seon Ae|Kim, Jung-Sun|Yu, Chang Sik|Kim, Jin Cheon
PMID: 18437011
Journal: Int J Colorectal Dis. 2008 Aug;23(8):801-6.
Title: Proximal colon cancer in patients aged 51-60 years of age should be tested for microsatellites instability. A comment on the Revised Bethesda Guidelines.
Author: Urso, E|Pucciarelli, S|Agostini, M|Maretto, I|Mescoli, C|Bertorelle, R|Viel, A|Rugge, M|Nitti, D
PMID: 18446350
Journal: Clin Cancer Res. 2008 May 1;14(9):2560-9.
Title: Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Author: Suehiro, Yutaka|Wong, Chi Wai|Chirieac, Lucian R|Kondo, Yutaka|Shen, Lanlan|Webb, C Renee|Chan, Yee Wai|Chan, Annie S Y|Chan, Tsun Leung|Wu, Tsung-Teh|Rashid, Asif|Hamanaka, Yuichiro|Hinoda, Yuji|Shannon, Rhonda L|Wang, Xuemei|Morris, Jeffrey|Issa, Jean-P
PMID: 18451217
Journal: Br J Surg. 2008 Jul;95(7):868-75.
Title: Cost analysis of biomarker testing for mismatch repair deficiency in node-positive colorectal cancer.
Author: Barrow, E|McMahon, R|Evans, D G|Levine, E|Hill, J
PMID: 18457354
Journal: Int J Cancer. 2008 Jul 15;123(2):258-263.
Title: Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency.
Author: Yang, Jia-Lin|Qu, Xian-Jun|Yu, Yan|Kohn, Elise C|Friedlander, Michael L
PMID: 18464258
Journal: Cancer. 2008 Jul 15;113(2):247-55.
Title: Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer.
Author: Guan, Haixia|Ji, Meiju|Hou, Peng|Liu, Zhi|Wang, Cuifang|Shan, Zhongyan|Teng, Weiping|Xing, Mingzhao
PMID: 18470905
Journal: J Biol Chem. 2008 Aug 1;283(31):21382-93.
Title: Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.
Author: Wagner, Mark W|Li, Long Shan|Morales, Julio C|Galindo, Cristi L|Garner, Harold R|Bornmann, William G|Boothman, David A
PMID: 18480061
Journal: Fam Cancer. 2008;7(4):331-7.
Title: Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.
Author: Magnusson, Susanne|Borg, Ake|Kristoffersson, Ulf|Nilbert, Mef|Wiebe, Thomas|Olsson, Hakan
PMID: 18481196
Journal: Oncol Rep. 2008 Jun;19(6):1571-6.
Title: Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer.
Author: Ide, Takao|Kitajima, Yoshihiko|Ohtaka, Kazuma|Mitsuno, Mayumi|Nakafusa, Yuji|Miyazaki, Kohji
PMID: 18497967
Journal: Cancer Biomark. 2008;4(2):55-61.
Title: Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer.
Author: Grunhage, Frank|Jungck, Matthias|Lamberti, Christof|Schulte-Witte, Hildegard|Plassmann, Dominik|Becker, Ursula|Rahner, Nils|Aretz, Stefan|Friedrichs, Nicolaus|Buettner, Reinhard|Sauerbruch, Tilman|Lammert, Frank
PMID: 18503156
Journal: Anticancer Res. 2008 Mar-Apr;28(2B):1341-7.
Title: Inherited cancer predisposition syndromes in Greece.
Author: Apessos, Angela|Papadopoulou, Eirini|Belogianni, Ioulia|Baratsis, Sotiris|Triantafillidis, John K|Kosmidis, Paris|Karydas, Eirini|Briasoulis, Evangelos|Pisiotis, Christos|Papazisis, Kostas|Nasioulas, George
PMID: 18505076
Journal: J Clin Oncol. 2008 Jun 1;26(16):2690-8.
Title: Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
Author: Braun, Michael S|Richman, Susan D|Quirke, Philip|Daly, Catherine|Adlard, Julian W|Elliott, Faye|Barrett, Jennifer H|Selby, Peter|Meade, Angela M|Stephens, Richard J|Parmar, Mahesh K B|Seymour, Matthew T
PMID: 18509181
Journal: Neoplasia. 2008 Jun;10(6):534-41.
Title: PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author: Nosho, Katsuhiko|Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Zepf, Dimity|Yan, Liying|Longtine, Janina A|Fuchs, Charles S|Ogino, Shuji
PMID: 18516290
Journal: Genes Chromosomes Cancer. 2008 Sep;47(9):803-9.
Title: The first functional study of MLH3 mutations found in cancer patients.
Author: Korhonen, Mari K|Vuorenmaa, Elina|Nystrom, Minna
PMID: 18521850
Journal: JAMA. 2008 Jun 4;299(21):2515-23.
Title: Association of family history with cancer recurrence and survival among patients with stage III colon cancer.
Author: Chan, Jennifer A|Meyerhardt, Jeffrey A|Niedzwiecki, Donna|Hollis, Donna|Saltz, Leonard B|Mayer, Robert J|Thomas, James|Schaefer, Paul|Whittom, Renaud|Hantel, Alexander|Goldberg, Richard M|Warren, Robert S|Bertagnolli, Monica|Fuchs, Charles S
PMID: 18523220
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008 Jun;25(3):326-30.
Title: [Comparison of clinical and genetic phenotypes between Chinese and Korean hereditary nonpolyposis colorectal cancer families].
Author: Shen, Hong|Yuan, Ying|Song, Yong-mao|Huang, Yan-qin|Zheng, Shu
PMID: 18543228
Journal: Dis Colon Rectum. 2008 Sep;51(9):1387-94.
Title: Ulcerative colitis-associated colorectal cancer is frequently associated with the microsatellite instability pathway.
Author: Fujiwara, Ichiro|Yashiro, Masakazu|Kubo, Naoshi|Maeda, Kiyoshi|Hirakawa, Kosei
PMID: 18546042
Journal: BMC Med Genet. 2008 Jun 11;9:52.
Title: The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population.
Author: Christensen, Lise Lotte|Madsen, Bo E|Wikman, Friedrik P|Wiuf, Carsten|Koed, Karen|Tjonneland, Anne|Olsen, Anja|Syvanen, Ann-Christine|Andersen, Claus L|Orntoft, Torben F
PMID: 18547406
Journal: PLoS Genet. 2008 Jun 13;4(6):e1000092.
Title: Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
Author: Chen, Peng-Chieh|Kuraguchi, Mari|Velasquez, John|Wang, Yuxun|Yang, Kan|Edwards, Robert|Gillen, Dan|Edelmann, Winfried|Kucherlapati, Raju|Lipkin, Steven M
PMID: 18551179
Journal: J Mol Diagn. 2008 Jul;10(4):301-7.
Title: Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part II. The utility of microsatellite instability testing.
Author: Zhang, Liying
PMID: 18556776
Journal: Cancer Res. 2008 Jun 15;68(12):4597-605.
Title: Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Author: Joensuu, Emmi I|Abdel-Rahman, Wael M|Ollikainen, Miina|Ruosaari, Salla|Knuutila, Sakari|Peltomaki, Paivi
PMID: 18559504
Journal: Virchows Arch. 2008 Jul;453(1):9-16.
Title: Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers.
Author: Muller, Annegret|Zielinski, Dirk|Friedrichs, Nicolaus|Oberschmid, Barbara|Merkelbach-Bruse, Sabine|Schackert, Hans K|Linnebacher, Markus|von Knebel Doeberitz, Magnus|Buttner, Reinhard|Ruschoff, Josef
PMID: 18581137
Journal: Int J Colorectal Dis. 2008 Nov;23(11):1033-9.
Title: Predictive and prognostic value of microsatellite instability in patients with advanced colorectal cancer treated with a fluoropyrimidine and oxaliplatin containing first-line chemotherapy. A report of the AIO Colorectal Study Group.
Author: Muller, C I|Schulmann, K|Reinacher-Schick, A|Andre, N|Arnold, D|Tannapfel, A|Arkenau, H|Hahn, S A|Schmoll, S H-J|Porschen, R|Schmiegel, W|Graeven, U
PMID: 18594845
Journal: World J Gastroenterol. 2008 Jun 21;14(23):3662-71.
Title: Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
Author: Mokarram, Pooneh|Naghibalhossaini, Fakhraddin|Saberi Firoozi, Mehdi|Hosseini, Seyed Vahid|Izadpanah, Ahmad|Salahi, Heshmetalah|Malek-Hosseini, Seyed Ali|Talei, Abdoulrasool|Mojallal, Mehra
PMID: 18595133
Journal: J Med Genet. 2008 Sep;45(9):557-63.
Title: Comparison of predictive models, clinical criteria and molecular tumour screening for the identification of patients with Lynch syndrome in a population-based cohort of colorectal cancer patients.
Author: Balmana, J|Balaguer, F|Castellvi-Bel, S|Steyerberg, E W|Andreu, M|Llor, X|Jover, R|Castells, A|Syngal, S
PMID: 18603628
Journal: Genes Chromosomes Cancer. 2008 Oct;47(10):835-44.
Title: The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer.
Author: Samowitz, Wade S|Curtin, Karen|Wolff, Roger K|Albertsen, Hans|Sweeney, Carol|Caan, Bette J|Ulrich, Cornelia M|Potter, John D|Slattery, Martha L
PMID: 18615680
Journal: Genes Chromosomes Cancer. 2008 Oct;47(10):906-14.
Title: Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients.
Author: Alemayehu, Aster|Sebova, Katarina|Fridrichova, Ivana
PMID: 18618713
Journal: Cancer Lett. 2008 Nov 18;271(1):153-7.
Title: Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.
Author: Frank, Bernd|Burwinkel, Barbara|Bermejo, Justo Lorenzo|Forsti, Asta|Hemminki, Kari|Houlston, Richard|Mangold, Elisabeth|Rahner, Nils|Friedl, Waltraut|Friedrichs, Nicolaus|Buettner, Reinhard|Engel, Christoph|Loeffler, Markus|Holinski-Feder, Elke|Morak, Mon
PMID: 18619730
Journal: Int J Cancer. 2008 Sep 15;123(6):1339-43.
Title: IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer.
Author: Reeves, Stuart G|Rich, Dominique|Meldrum, Cliff J|Colyvas, Kim|Kurzawski, Grzegorz|Suchy, Janina|Lubinski, Jan|Scott, Rodney J
PMID: 18623088
Journal: Cancer Sci. 2008 Sep;99(9):1715-9.
Title: Molecular epidemiological and mutational analysis of DNA mismatch repair (MMR) genes in endometrial cancer patients with HNPCC-associated familial predisposition to cancer.
Author: Hirai, Y|Banno, K|Suzuki, M|Ichikawa, Y|Udagawa, Y|Sugano, K|Miki, Y
PMID: 18624996
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Jul;11(4):317-21.
Title: [Clinical value of screening hereditary nonpolyposis colorectal cancer in China with protocol recommended by NCCN guidelines].
Author: Shen, Kai|Wang, Shan|Ye, Ying-Jiang|Yin, Mu-Jun|Yang, Xiao-Dong|Xu, Feng|Liang, Bin|Jiang, Ke-Wei|Cui, Zhi-Rong
PMID: 18636350
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Jul;11(4):358-61.
Title: [Study of germline mutation of hMSH2, hMSH6 and hMLH1 and methylation of hMLH1 in microsatellite instability colorectal cancer].
Author: Ni, Min|Jin, Hei-Ying|Ding, Yi-Jiang|Liu, Fei|Ding, Shu-Qing|Fan, Zhi-Min|Wang, Ye-Huang
PMID: 18636359
Journal: Clin Gastroenterol Hepatol. 2008 Dec;6(12):1385-8.
Title: Altered DNA mismatch repair expression in synchronous and metachronous colorectal cancers.
Author: Aslanian, Harry R|Burgart, Lawrence J|Harrington, Jonathan J|Mahoney, Douglas W|Zinsmeister, Alan R|Thibodeau, Stephen N|Ahlquist, David A
PMID: 18639494
Journal: Curr Opin Genet Dev. 2008 Jun;18(3):273-9.
Title: Transgenerational epigenetic inheritance in health and disease.
Author: Whitelaw, Nadia C|Whitelaw, Emma
PMID: 18662779
Journal: Am J Surg Pathol. 2008 Aug;32(8):1246-51.
Title: Interpretation of immunohistochemistry for mismatch repair proteins is only reliable in a specialized setting.
Author: Overbeek, Lucia I H|Ligtenberg, Marjolijn J L|Willems, Riki W|Hermens, Rosella P M G|Blokx, Willeke A M|Dubois, Stefan V|van der Linden, Hans|Meijer, Jos W R|Mlynek-Kersjes, Maria L|Hoogerbrugge, Nicoline|Hebeda, Konnie M|van Krieken, Joannes H J M
PMID: 18677806
Journal: Oncogene. 2008 Oct 23;27(49):6313-21.
Title: Differences and evolution of the methods for the assessment of microsatellite instability.
Author: Laghi, L|Bianchi, P|Malesci, A
PMID: 18679418
Journal: Gene. 2008 Nov 1;423(2):188-93.
Title: Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1.
Author: Zhao, Yan|Miyashita, Kaname|Ando, Takayuki|Kakeji, Yoshihiro|Yamanaka, Takeharu|Taguchi, Kenichi|Ushijima, Toshikazu|Oda, Shinya|Maehara, Yoshihiko
PMID: 18692554
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2044-51.
Title: Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States.
Author: Kastrinos, Fay|Stoffel, Elena M|Balmana, Judith|Steyerberg, Ewout W|Mercado, Rowena|Syngal, Sapna
PMID: 18708397
Journal: Hum Genet. 2008 Sep;124(2):105-22.
Title: Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?
Author: Wimmer, Katharina|Etzler, Julia
PMID: 18709565
Journal: Int J Cancer. 2008 Nov 15;123(10):2456-9.
Title: MLH1 -93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer.
Author: Allan, James M|Shorto, Jennifer|Adlard, Julian|Bury, Jonathan|Coggins, Ron|George, Rina|Katory, Mark|Quirke, Philip|Richman, Susan|Scott, Daniel|Scott, Kathryn|Seymour, Matthew|Travis, Lois B|Worrillow, Lisa J|Bishop, D Timothy|Cox, Angela
PMID: 18712731
Journal: Geriatr Gerontol Int. 2008 Jun;8(2):65-72.
Title: Role of DNA repair systems in malignant tumor development in the elderly.
Author: Arai, Tomio|Sawabe, Motoji|Hosoi, Takayuki|Tanaka, Noriko
PMID: 18713157
Journal: Chin Med J (Engl). 2008 Jul 20;121(14):1265-8.
Title: Clinical features and hMSH2/hMLH1 germ-line mutations in Chinese patients with hereditary nonpolyposis colorectal cancer.
Author: Shen, Xuan-san|Zhao, Bo|Wang, Zhen-jun
PMID: 18713544
Journal: Mol Cancer. 2008 Aug 21;7:68.
Title: Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study.
Author: Brim, Hassan|Mokarram, Pooneh|Naghibalhossaini, Fakhraddin|Saberi-Firoozi, Mehdi|Al-Mandhari, Mansour|Al-Mawaly, Kamla|Al-Mjeni, Rayhaneh|Al-Sayegh, Abeer|Raeburn, Sandy|Lee, Edward|Giardiello, Francis|Smoot, Duane T|Vilkin, Alexander|Boland, C Richard|Go
PMID: 18718023
Journal: Am J Gastroenterol. 2008 Nov;103(11):2825-35; quiz 2836.
Title: Identification in daily practice of patients with Lynch syndrome (hereditary nonpolyposis colorectal cancer): revised Bethesda guidelines-based approach versus molecular screening.
Author: Julie, Catherine|Tresallet, Christophe|Brouquet, Antoine|Vallot, Celine|Zimmermann, Ute|Mitry, Emmanuel|Radvanyi, Francois|Rouleau, Etienne|Lidereau, Rosette|Coulet, Florence|Olschwang, Sylviane|Frebourg, Thierry|Rougier, Philippe|Nordlinger, Bernard|Laur
PMID: 18759827
Journal: Rev Med Chil. 2008 Jun;136(6):757-62.
Title: [Hereditary non-polyposis colorectal cancer. Report of four siblings].
Author: Zarate, Alejandro|Alvarez, Karin|Wielandt, Ana Maria|Hevia, Montserrat|De la Fuente, Marjorie|Carvallo, Pilar|Lopez-Kostner, Francisco
PMID: 18769833
Journal: Clin Chem. 2008 Nov;54(11):1844-54.
Title: Multiplex SNaPshot genotyping for detecting loss of heterozygosity in the mismatch-repair genes MLH1 and MSH2 in microsatellite-unstable tumors.
Author: Bujalkova, Maria|Zavodna, Katarina|Krivulcik, Tomas|Ilencikova, Denisa|Wolf, Brigitte|Kovac, Michal|Karner-Hanusch, Judith|Heinimann, Karl|Marra, Giancarlo|Jiricny, Josef|Bartosova, Zdena
PMID: 18772310
Journal: BMC Cancer. 2008 Sep 9;8:255.
Title: BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
Author: Velho, Sergia|Moutinho, Catia|Cirnes, Luis|Albuquerque, Cristina|Hamelin, Richard|Schmitt, Fernando|Carneiro, Fatima|Oliveira, Carla|Seruca, Raquel
PMID: 18782444
Journal: Int J Cancer. 2008 Dec 1;123(11):2587-93.
Title: Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
Author: Kim, Yong Ho|Kakar, Sanjay|Cun, Lisa|Deng, Guoren|Kim, Young S
PMID: 18798261
Journal: Med Pregl. 2008 Jan-Feb;61(1-2):79-82.
Title: [Lynch syndrome I: a case report].
Author: Zivkovic, Vesna|Katic, Vuka|Gligorijevic, Jasmina|Andelkovic, Zlatibor|Petrovic, Aleksandar|Krstic, Miljan
PMID: 18798480
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Sep;11(5):462-4.
Title: [Comparison of the sensibility and specificity between single-stranded conformation polymorphism and denaturing high-performance liquid chromatography in screening hMSH2 and hMLH1 gene mutations in hereditary non-polyposis colorectal cancer].
Author: Wei, Guang-hui|Zhao, Bo|Wang, Zhen-jun
PMID: 18803051
Journal: Oncol Rep. 2008 Oct;20(4):921-7.
Title: DNA methylotype analysis in colorectal cancer.
Author: Yu, Jinsheng|Freimuth, Robert R|Culverhouse, Robert|Marsh, Sharon|Watson, Mark A|McLeod, Howard L
PMID: 18813836
Journal: Histol Histopathol. 2008 Dec;23(12):1495-502.
Title: RAD50/MRE11/NBS1 proteins in relation to tumour development and prognosis in patients with microsatellite stable colorectal cancer.
Author: Gao, Jingfang|Zhang, Hong|Arbman, Gunnar|Sun, Xiao-Feng
PMID: 18830935
Journal: Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title: CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author: Lee, Sun|Cho, Nam-Yun|Yoo, Eun Joo|Kim, Jung Ho|Kang, Gyeong Hoon
PMID: 18834226
Journal: Gastroenterology. 2008 Nov;135(5):1654-1664.e2.
Title: An inactivating mutation in HDAC2 leads to dysregulation of apoptosis mediated by APAF1.
Author: Hanigan, Christin L|Van Engeland, Manon|De Bruine, Adriaan P|Wouters, Kim A|Weijenberg, Matty P|Eshleman, James R|Herman, James G
PMID: 18834886
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2895-8.
Title: A prospective study of dietary folate and vitamin B and colon cancer according to microsatellite instability and KRAS mutational status.
Author: Schernhammer, Eva S|Giovannuccci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 18843035
Journal: Mutat Res. 2008 Dec 15;648(1-2):40-5.
Title: Do polymorphisms and haplotypes of mismatch repair genes modulate risk of sporadic colorectal cancer?
Author: Tulupova, E|Kumar, R|Hanova, M|Slyskova, J|Pardini, B|Polakova, V|Naccarati, A|Vodickova, L|Novotny, J|Halamkova, J|Hemminki, K|Vodicka, P
PMID: 18851982
Journal: Chirurg. 2008 Nov;79(11):1038-46.
Title: [Hereditary colorectal cancer].
Author: Moslein, G
PMID: 18853126
Journal: Cancer Res. 2008 Oct 15;68(20):8465-72.
Title: Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.
Author: Haugen, Astrid C|Goel, Ajay|Yamada, Kanae|Marra, Giancarlo|Nguyen, Thuy-Phuong|Nagasaka, Takeshi|Kanazawa, Shinsaku|Koike, Junichi|Kikuchi, Yoshinori|Zhong, Xiaoling|Arita, Michitsune|Shibuya, Kazutoshi|Oshimura, Mitsuo|Hemmi, Hiromichi|Boland, C Richard|
PMID: 18922920
Journal: Cancer Res. 2008 Oct 15;68(20):8541-6.
Title: Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.
Author: Barault, Ludovic|Charon-Barra, Celine|Jooste, Valerie|de la Vega, Mathilde Funes|Martin, Laurent|Roignot, Patrick|Rat, Patrick|Bouvier, Anne-Marie|Laurent-Puig, Pierre|Faivre, Jean|Chapusot, Caroline|Piard, Francoise
PMID: 18922929
Journal: Lab Invest. 2008 Dec;88(12):1367-75.
Title: MethyQESD, a robust and fast method for quantitative methylation analyses in HNPCC diagnostics using formalin-fixed and paraffin-embedded tissue samples.
Author: Bettstetter, Marcus|Dechant, Stefan|Ruemmele, Petra|Vogel, Corinna|Kurz, Katrin|Morak, Monika|Keller, Gisela|Holinski-Feder, Elke|Hofstaedter, Ferdinand|Dietmaier, Wolfgang
PMID: 18936738
Journal: Z Gastroenterol. 2008 Oct;46(10):1202-6.
Title: [Epigenetic alterations in colorectal carcinomas and precancerous lesions].
Author: Tischoff, I|Tannapfel, A
PMID: 18937191
Journal: Eur J Cancer. 2008 Nov;44(17):2689-95.
Title: Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions.
Author: Ramirez, N|Bandres, E|Navarro, A|Pons, A|Jansa, S|Moreno, I|Martinez-Rodenas, F|Zarate, R|Bitarte, N|Monzo, M|Garcia-Foncillas, J
PMID: 18938072
Journal: Br J Cancer. 2008 Nov 18;99(10):1607-12.
Title: Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines.
Author: Vilar, E|Scaltriti, M|Balmana, J|Saura, C|Guzman, M|Arribas, J|Baselga, J|Tabernero, J
PMID: 18941461
Journal: Oncol Rep. 2008 Nov;20(5):999-1004.
Title: Oncoprotein Bcl-2 and microsatellite instability are associated with disease-free survival and treatment response in colorectal cancer.
Author: Bendardaf, Riyad|Lamlum, Hanan|Ristamaki, Raija|Syrjanen, Kari|Pyrhonen, Seppo
PMID: 18949393
Journal: Acta Obstet Gynecol Scand. 2008;87(11):1129-35.
Title: Risk of gynecologic cancers in Danish hereditary non-polyposis colorectal cancer families.
Author: Boilesen, Astrid Elisabeth Bruun|Bisgaard, Marie Luise|Bernstein, Inge
PMID: 18972272
Journal: Histopathology. 2008 Nov;53(5):588-98.
Title: Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Author: Nosho, K|Kawasaki, T|Chan, A T|Ohnishi, M|Suemoto, Y|Kirkner, G J|Fuchs, C S|Ogino, S
PMID: 18983468
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3208-15.
Title: Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.
Author: Poynter, Jenny N|Siegmund, Kimberly D|Weisenberger, Daniel J|Long, Tiffany I|Thibodeau, Stephen N|Lindor, Noralane|Young, Joanne|Jenkins, Mark A|Hopper, John L|Baron, John A|Buchanan, Dan|Casey, Graham|Levine, A Joan|Le Marchand, Loic|Gallinger, Steven|Ba
PMID: 18990764
Journal: Neoplasma. 2008;55(6):463-71.
Title: Novel approaches in evaluation of pathogenicity of single-base exonic germline changes involving the mismatch repair genes MLH1 and MSH2 in diagnostics of Lynch syndrome.
Author: Gerykova-Bujalkova, M|Krivulcik, T|Bartosova, Z
PMID: 18999873
Journal: PLoS One. 2008;3(11):e3698.
Title: Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author: Nosho, Katsuhiko|Irahara, Natsumi|Shima, Kaori|Kure, Shoko|Kirkner, Gregory J|Schernhammer, Eva S|Hazra, Aditi|Hunter, David J|Quackenbush, John|Spiegelman, Donna|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19002263
Journal: Br J Cancer. 2008 Dec 16;99(12):2001-5.
Title: Statistical strategies to improve the efficiency of molecular studies of colorectal cancer prognosis.
Author: Qu, P|Chu, H|Ibrahim, J G|Peacock, J|Shen, X J|Tepper, J|Sandler, R S|Keku, T O
PMID: 19018265
Journal: Eur J Gastroenterol Hepatol. 2008 Nov;20(11):1101-5.
Title: Report on de-novo mutation in the MSH2 gene as a rare event in hereditary nonpolyposis colorectal cancer.
Author: Morak, Monika|Laner, Andreas|Scholz, Michael|Madorf, Trisari|Holinski-Feder, Elke
PMID: 19047842
Journal: Cutis. 2008 Oct;82(4):252-6.
Title: Muir-Torre syndrome: a rare but important disorder.
Author: Hare, Holly H|Mahendraker, Neetu|Sarwate, Sandhya|Tangella, Krishnarao
PMID: 19055168
Journal: P R Health Sci J. 2008 Dec;27(4):322-7.
Title: MSH-2 and MLH-1 protein expression in Muir Torre syndrome-related and sporadic sebaceous neoplasms.
Author: Morales-Burgos, Adisbeth|Sanchez, Jorge L|Figueroa, Luz D|De Jesus-Monge, Wilfredo E|Cruz-Correa, Marcia R|Gonzalez-Keelan, Carmen|Nazario, Cruz Maria
PMID: 19069357
Journal: Acta Chir Iugosl. 2008;55(3):39-44.
Title: Prognostic value of clinical, pathological and immunohistochemical markers in stage II colon cancer patients.
Author: Stor, Z|Frkovic, G S|Bracko, M|Repse, S
PMID: 19069691
Journal: Crit Rev Oncog. 2008;14(1):1-22; discussion 23-31.
Title: Lynch syndrome and related familial colorectal cancers.
Author: Abdel-Rahman, Wael M|Peltomaki, Paivi
PMID: 19105568
Journal: Mol Cancer. 2008 Dec 31;7:94.
Title: Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author: Ahlquist, Terje|Lind, Guro E|Costa, Vera L|Meling, Gunn I|Vatn, Morten|Hoff, Geir S|Rognum, Torleiv O|Skotheim, Rolf I|Thiis-Evensen, Espen|Lothe, Ragnhild A
PMID: 19117505
Journal: Ann Acad Med Stetin. 2008;54(1):106-11.
Title: [Dentistry anomalies in patients with Lynch syndrome and familial adenomatous polyposis].
Author: Budzynska, Agata
PMID: 19127816
Journal: Ginekol Pol. 2008 Dec;79(12):826-34.
Title: Analysis of hMLH1 and hMSH2 expression in cisplatin-treated ovarian cancer patients.
Author: Magnowska, Magdalena|Surowiak, Pawel|Nowak-Markwitz, Ewa|Michalak, Marcin|Magnowski, Piotr|Rokita, Wojciech|Kedzia, Helena|Zabel, Maciej|Spaczynski, Marek
PMID: 19175039
Journal: Curr Genomics. 2008 Mar;9(1):1-10.
Title: The genomics of colorectal cancer: state of the art.
Author: Beggs, Andrew D|Hodgson, Shirley V
PMID: 19424478
Journal: Hered Cancer Clin Pract. 2008 Feb 15;6(1):15-21.
Title: Thyroid cancer in a patient with a germline MSH2 mutation. Case report and review of the Lynch syndrome expanding tumour spectrum.
Author: Stulp, Rein P|Herkert, Johanna C|Karrenbeld, Arend|Mol, Bart|Vos, Yvonne J|Sijmons, Rolf H
PMID: 19706203
Journal: Mol Med Rep. 2008 Jul-Aug;1(4):549-53.
Title: Risk analysis of colorectal cancer in women with endometrial carcinoma.
Author: Fornasarig, Mara|Minisini, Alessandro Marco|Clementi, Silvia|Bidoli, Ettore|Viel, Alessandra|Cannizzaro, Renato|Campagnutta, Elio|Boz, Gianni|Libra, Massimo
PMID: 21479448
Journal: Gut. 2009 May;58(5):661-7.
Title: Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors.
Author: Campbell, P T|Curtin, K|Ulrich, C M|Samowitz, W S|Bigler, J|Velicer, C M|Caan, B|Potter, J D|Slattery, M L
PMID: 18523027
Journal: Fam Cancer. 2009;8(1):67-73.
Title: MLPA mutation detection in Argentine HNPCC and FAP families.
Author: Gomez, Laura C|Marzese, Diego M|Adi, Jose|Bertani, Diego|Ibarra, Jorge|Mol, Bart|Vos, Ivonne Johanna|De Marchi, Gabriela|Roque, Maria
PMID: 18615272
Journal: Crit Rev Oncol Hematol. 2009 Jan;69(1):28-44.
Title: Hereditary ovarian cancer.
Author: Russo, Antonio|Calo, Valentina|Bruno, Loredana|Rizzo, Sergio|Bazan, Viviana|Di Fede, Gaetana
PMID: 18656380
Journal: Eur J Cancer. 2009 Feb;45(3):365-73.
Title: The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status.
Author: Jover, Rodrigo|Zapater, Pedro|Castells, Antoni|Llor, Xavier|Andreu, Montserrat|Cubiella, Joaquin|Balaguer, Francesc|Sempere, Laura|Xicola, Rosa M|Bujanda, Luis|Rene, Josep M|Clofent, Juan|Bessa, Xavier|Morillas, Juan D|Nicolas-Perez, David|Pons, Elisenda|
PMID: 18722765
Journal: Fam Cancer. 2009;8(2):85-94.
Title: Recurring MLH1 deleterious mutations in unrelated Chinese Lynch syndrome families in Singapore.
Author: Yap, Hui-Ling|Chieng, Wei-Shieng|Lim, Jasmine Rui-Chen|Lim, Robert Seng-Cheong|Soo, Ross|Guo, Jiayi|Lee, Soo-Chin
PMID: 18726168
Journal: Genes Chromosomes Cancer. 2009 Jan;48(1):1-9.
Title: Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Author: Sweeney, Carol|Boucher, Kenneth M|Samowitz, Wade S|Wolff, Roger K|Albertsen, Hans|Curtin, Karen|Caan, Bette J|Slattery, Martha L
PMID: 18767147
Journal: Eur J Hum Genet. 2009 Feb;17(2):159-64.
Title: Compound heterozygosity for two MSH2 mutations suggests mild consequences of the initiation codon variant c.1A>G of MSH2.
Author: Kets, Carolien M|Hoogerbrugge, Nicoline|van Krieken, Joannes H J M|Goossens, Monique|Brunner, Han G|Ligtenberg, Marjolijn J L
PMID: 18781192
Journal: Fam Cancer. 2009;8(2):119-26.
Title: Identification and characterization of a novel MLH1 genomic rearrangement as the cause of HNPCC in a Tunisian family: evidence for a homologous Alu-mediated recombination.
Author: Aissi-Ben Moussa, Sana|Moussa, Amel|Lovecchio, Tonio|Kourda, Nadia|Najjar, Taoufik|Ben Jilani, Sarra|El Gaaied, Amel|Porchet, Nicole|Manai, Mohamed|Buisine, Marie-Pierre
PMID: 18792805
Journal: Gut. 2009 Jan;58(1):90-6.
Title: CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author: Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Kawasaki, Takako|Meyerhardt, Jeffrey A|Loda, Massimo|Giovannucci, Edward L|Fuchs, Charles S
PMID: 18832519
Journal: Fam Cancer. 2009;8(2):145-51.
Title: High risk of endometrial cancer in colorectal cancer kindred is pathognomonic for MMR-mutation carriers.
Author: Grindedal, Eli Marie|Blanco, Ignacio|Stormorken, Astrid|Maehle, Lovise|Clark, Neal|Gonzalez, Sara|Capella, Gabriel|Vasen, Hans|Burn, John|Moller, Pal
PMID: 18841495
Journal: Virchows Arch. 2009 Jan;454(1):115-24.
Title: HNPCC-associated synchronous early-stage signet-ring cell carcinomas of colonic origin. A comparative morphological and immunohistochemical study of an intramucosal and a submucosal example.
Author: Klarskov, Louise|Bernstein, Inge|Holck, Susanne
PMID: 19002494
Journal: Neuro Oncol. 2009 Aug;11(4):452-5.
Title: Identifying Muir-Torre syndrome in a patient with glioblastoma multiforme.
Author: Park, Deric M|Yeaney, Gabrielle A|Hamilton, Ronald L|Mabold, Jennifer|Urban, Nikki|Appleman, Leonard|Flickinger, John|Lieberman, Frank|Mintz, Arlan
PMID: 19028998
Journal: Carcinogenesis. 2009 Mar;30(3):472-9.
Title: Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Author: Joshi, Amit D|Corral, Roman|Siegmund, Kimberly D|Haile, Robert W|Le Marchand, Loic|Martinez, Maria Elena|Ahnen, Dennis J|Sandler, Robert S|Lance, Peter|Stern, Mariana C
PMID: 19029193
Journal: Lung Cancer. 2009 Jun;64(3):282-8.
Title: Phenotypic mismatch repair hMSH2 and hMLH1 gene expression profiles in primary non-small cell lung carcinomas.
Author: Vageli, Dimitra|Daniil, Zoe|Dahabreh, Jubrail|Karagianni, Eleni|Vamvakopoulou, Dimitra N|Ioannou, Maria G|Scarpinato, Karin|Vamvakopoulos, Nikos C|Gourgoulianis, Konstantinos I|Koukoulis, George K
PMID: 19056144
Journal: Oncogene. 2009 Feb 12;28(6):899-909.
Title: Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters.
Author: Menigatti, M|Truninger, K|Gebbers, J-O|Marbet, U|Marra, G|Schar, P
PMID: 19060925
Journal: Int J Cancer. 2009 Mar 1;124(5):1097-102.
Title: Population-based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial test.
Author: Schofield, Lyn|Watson, Natasha|Grieu, Fabienne|Li, Wei Qi|Zeps, Nik|Harvey, Jennet|Stewart, Colin|Abdo, Michael|Goldblatt, Jack|Iacopetta, Barry
PMID: 19072991
Journal: Cancer Genet Cytogenet. 2009 Jan 15;188(2):61-4.
Title: Three new nonsense mutations of MLH1 and MSH2 genes in Korean families with hereditary nonpolyposis colorectal cancer.
Author: Yoon, Seoyoung|Park, Tae Sung|Kim, Nam Kyu|Lee, Kyung-A|Kim, Juwon|Song, Jaewoo|Kim, Bo-Young|Choi, Jong Rak
PMID: 19100506
Journal: Fam Cancer. 2009;8(3):187-94.
Title: Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I.
Author: Toledano, Helen|Goldberg, Yael|Kedar-Barnes, Inbal|Baris, Hagit|Porat, Rinnat M|Shochat, Chen|Bercovich, Dani|Pikarsky, Eli|Lerer, Israela|Yaniv, Isaac|Abeliovich, Dvorah|Peretz, Tamar
PMID: 19101824
Journal: Neoplasia. 2009 Jan;11(1):87-95.
Title: JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author: Nosho, Katsuhiko|Shima, Kaori|Kure, Shoko|Irahara, Natsumi|Baba, Yoshifumi|Chen, Li|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 19107235
Journal: Int J Cancer. 2009 Apr 15;124(8):1887-91.
Title: Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.
Author: Koessler, Thibaud|Azzato, Elizabeth M|Perkins, Barbara|Macinnis, Robert J|Greenberg, David|Easton, Douglas F|Pharoah, Paul D P
PMID: 19115210
Journal: Cancer Biol Ther. 2009 Jan;8(1):94-100. Epub 2009 Jan 20.
Title: Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer.
Author: Howard, J Harrison|Frolov, Andrey|Tzeng, Ching-Wei D|Stewart, Ashley|Midzak, Andrew|Majmundar, Amar|Godwin, Andrew|Heslin, Martin|Bellacosa, Alfonso|Arnoletti, J Pablo
PMID: 19127118
Journal: Cancer. 2009 Feb 15;115(4):760-9.
Title: Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.
Author: Vilkin, Alex|Niv, Yaron|Nagasaka, Takeshi|Morgenstern, Sarah|Levi, Zohar|Fireman, Zvi|Fuerst, Florentine|Goel, Ajay|Boland, C Richard
PMID: 19127559
Journal: Fam Cancer. 2009;8(3):209-13.
Title: Sarcomas associated with hereditary nonpolyposis colorectal cancer: broad anatomical and morphological spectrum.
Author: Nilbert, Mef|Therkildsen, Christina|Nissen, Anja|Akerman, Mans|Bernstein, Inge
PMID: 19130300
Journal: Colorectal Dis. 2009 Feb;11(2):126-30.
Title: Surveillance colonoscopy improves survival in a cohort of subjects with a single mismatch repair gene mutation.
Author: Stupart, D A|Goldberg, P A|Algar, U|Ramesar, R
PMID: 19143775
Journal: Carcinogenesis. 2009 Mar;30(3):494-9.
Title: Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B.
Author: Asaka, Shin-ichi|Arai, Yoshiko|Nishimura, Yoji|Yamaguchi, Kensei|Ishikubo, Tsutomu|Yatsuoka, Toshimasa|Tanaka, Yoichi|Akagi, Kiwamu
PMID: 19147861
Journal: Mol Carcinog. 2009 Aug;48(8):742-50.
Title: Nuclear import of human MLH1, PMS2, and MutLalpha: redundancy is the key.
Author: Leong, Vivian|Lorenowicz, Jessica|Kozij, Natalie|Guarne, Alba
PMID: 19148896
Journal: Fam Cancer. 2009;8(3):215-20.
Title: Evidence of tumor microsatellite instability in gastric cancer with familial aggregation.
Author: Pedrazzani, Corrado|Corso, Giovanni|Velho, Sergia|Leite, Marina|Pascale, Valeria|Bettarini, Francesca|Marrelli, Daniele|Seruca, Raquel|Roviello, Franco
PMID: 19152022
Journal: BMC Cancer. 2009 Jan 20;9:25.
Title: Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression.
Author: Jensen, Soren A|Vainer, Ben|Kruhoffer, Mogens|Sorensen, Jens B
PMID: 19154585
Journal: Eur J Hum Genet. 2009 Jul;17(7):919-27.
Title: Type A microsatellite instability in pediatric gliomas as an indicator of Turcot syndrome.
Author: Giunti, Laura|Cetica, Valentina|Ricci, Ugo|Giglio, Sabrina|Sardi, Iacopo|Paglierani, Milena|Andreucci, Elena|Sanzo, Massimiliano|Forni, Marco|Buccoliero, Anna Maria|Genitori, Lorenzo|Genuardi, Maurizio
PMID: 19156169
Journal: Genes Chromosomes Cancer. 2009 Apr;48(4):340-50.
Title: Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.
Author: Ou, Jianghua|Rasmussen, Merete|Westers, Helga|Andersen, Sofie D|Jager, Paul O|Kooi, Krista A|Niessen, Renee C|Eggen, Bart J L|Nielsen, Finn C|Kleibeuker, Jan H|Sijmons, Rolf H|Rasmussen, Lene J|Hofstra, Robert M W
PMID: 19156873
Journal: Ann Oncol. 2009 Jul;20(7):1216-22.
Title: MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
Author: de Vogel, S|Weijenberg, M P|Herman, J G|Wouters, K A D|de Goeij, A F P M|van den Brandt, P A|de Bruine, A P|van Engeland, M
PMID: 19164452
Journal: Br J Cancer. 2009 Jan 27;100(2):266-73.
Title: Deficient mismatch repair system in patients with sporadic advanced colorectal cancer.
Author: Koopman, M|Kortman, G A M|Mekenkamp, L|Ligtenberg, M J L|Hoogerbrugge, N|Antonini, N F|Punt, C J A|van Krieken, J H J M
PMID: 19165197
Journal: Int J Cancer. 2009 May 15;124(10):2333-40.
Title: Large genomic rearrangements and germline epimutations in Lynch syndrome.
Author: Gylling, Annette|Ridanpaa, Maaret|Vierimaa, Outi|Aittomaki, Kristiina|Avela, Kristiina|Kaariainen, Helena|Laivuori, Hannele|Poyhonen, Minna|Sallinen, Satu-Leena|Wallgren-Pettersson, Carina|Jarvinen, Heikki J|Mecklin, Jukka-Pekka|Peltomaki, Paivi
PMID: 19173287
Journal: Clin Cancer Res. 2009 Feb 1;15(3):762-9.
Title: An interstitial deletion at 3p21.3 results in the genetic fusion of MLH1 and ITGA9 in a Lynch syndrome family.
Author: Meyer, Claus|Brieger, Angela|Plotz, Guido|Weber, Nicole|Passmann, Sandra|Dingermann, Theo|Zeuzem, Stefan|Trojan, Joerg|Marschalek, Rolf
PMID: 19188145
Journal: Clin Cancer Res. 2009 Feb 15;15(4):1155-61.
Title: Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.
Author: Kumar, Krishan|Brim, Hassan|Giardiello, Francis|Smoot, Duane T|Nouraie, Mehdi|Lee, Edward L|Ashktorab, Hassan
PMID: 19190129
Journal: Am J Surg Pathol. 2009 Jun;33(6):925-33.
Title: Selection of endometrial carcinomas for DNA mismatch repair protein immunohistochemistry using patient age and tumor morphology enhances detection of mismatch repair abnormalities.
Author: Garg, Karuna|Leitao, Mario M Jr|Kauff, Noah D|Hansen, Jessica|Kosarin, Kristi|Shia, Jinru|Soslow, Robert A
PMID: 19238076
Journal: Fam Cancer. 2009;8(4):313-23.
Title: Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis.
Author: Walsh, Michael D|Buchanan, Daniel D|Walters, Rhiannon|Roberts, Aedan|Arnold, Sven|McKeone, Diane|Clendenning, Mark|Ruszkiewicz, Andrew R|Jenkins, Mark A|Hopper, John L|Goldblatt, Jack|George, Jillian|Suthers, Graeme K|Phillips, Kerry|Young, Graeme P|Macra
PMID: 19241144
Journal: J Natl Cancer Inst. 2009 Mar 4;101(5):331-40.
Title: Prediction of Lynch syndrome in consecutive patients with colorectal cancer.
Author: Green, Roger C|Parfrey, Patrick S|Woods, Michael O|Younghusband, H Banfield
PMID: 19244167
Journal: World J Gastroenterol. 2009 Feb 28;15(8):983-9.
Title: Genetic diagnosis strategy of hereditary non-polyposis colorectal cancer.
Author: Sheng, Jian-Qiu|Zhang, Hong|Ji, Min|Fu, Lei|Mu, Hong|Zhang, Ming-Zhi|Huang, Ji-Sheng|Han, Min|Li, Ai-Qin|Wei, Zhi|Sun, Zi-Qin|Wu, Zi-Tao|Xia, Chang-Hong|Li, Shi-Rong
PMID: 19248199
Journal: Eur J Cancer. 2009 May;45(8):1485-93.
Title: A new strategy to screen MMR genes in Lynch Syndrome: HA-CAE, MLPA and RT-PCR.
Author: Perez-Cabornero, Lucia|Velasco, Eladio|Infante, Mar|Sanz, David|Lastra, Enrique|Hernandez, Lara|Miner, Cristina|Duran, Mercedes
PMID: 19250818
Journal: Am J Surg Pathol. 2009 May;33(5):691-704.
Title: Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions.
Author: Ruemmele, Petra|Dietmaier, Wolfgang|Terracciano, Luigi|Tornillo, Luigi|Bataille, Frauke|Kaiser, Annette|Wuensch, Peter-Heinz|Heinmoeller, Ernst|Homayounfar, Kia|Luettges, Jutta|Kloeppel, Guenter|Sessa, Fausto|Edmonston, Tina Bocker|Schneider-Stock, Regine
PMID: 19252434
Journal: Hum Mutat. 2009 May;30(5):757-70.
Title: Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics.
Author: Arnold, Sven|Buchanan, Daniel D|Barker, Melissa|Jaskowski, Lesley|Walsh, Michael D|Birney, Genevieve|Woods, Michael O|Hopper, John L|Jenkins, Mark A|Brown, Melissa A|Tavtigian, Sean V|Goldgar, David E|Young, Joanne P|Spurdle, Amanda B
PMID: 19267393
Journal: J Clin Oncol. 2009 Apr 10;27(11):1814-21.
Title: Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.
Author: Bertagnolli, Monica M|Niedzwiecki, Donna|Compton, Carolyn C|Hahn, Hejin P|Hall, Margaret|Damas, Beatrice|Jewell, Scott D|Mayer, Robert J|Goldberg, Richard M|Saltz, Leonard B|Warren, Robert S|Redston, Mark
PMID: 19273709
Journal: Gynecol Oncol. 2009 May;113(2):153-8.
Title: Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma.
Author: Arabi, Haitham|Guan, Hui|Kumar, Sanjeev|Cote, Michele|Bandyopadhyay, Sudeshna|Bryant, Christopher|Shah, Jay|Abdul-Karim, Fadi W|Munkarah, Adnan R|Ali-Fehmi, Rouba
PMID: 19275958
Journal: Bosn J Basic Med Sci. 2009 Feb;9(1):10-8.
Title: Molecular analysis: microsatellity instability and loss of heterozygosity of tumor suppressor gene in hereditary non-polyposis colorectal cancers (HNPCC).
Author: Hadziavdic, Vesna|Pavlovic-Calic, Nada|Eminovic, Izet
PMID: 19284389
Journal: Cancer Gene Ther. 2009 Sep;16(9):683-92.
Title: MLH1 deficiency enhances tumor cell sensitivity to ganciclovir.
Author: O'Konek, J J|Boucher, P D|Iacco, A A|Wilson, T E|Shewach, D S
PMID: 19300472
Journal: J Gastrointestin Liver Dis. 2009 Mar;18(1):33-8.
Title: Introduction of cytogenetic tests in colorectal cancer screening.
Author: Suceveanu, Andra Iulia|Suceveanu, Adrian|Voinea, Florea|Mazilu, Laura|Mixici, Francisc|Adam, Tatiana
PMID: 19337631
Journal: Am J Surg Pathol. 2009 Jun;33(6):934-44.
Title: Towards identification of hereditary DNA mismatch repair deficiency: sebaceous neoplasm warrants routine immunohistochemical screening regardless of patient's age or other clinical characteristics.
Author: Orta, Lurmag|Klimstra, David S|Qin, Jing|Mecca, Patricia|Tang, Laura H|Busam, Klaus J|Shia, Jinru
PMID: 19342947
Journal: Clin Cancer Res. 2009 Apr 15;15(8):2829-39.
Title: Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Author: Vilar, Eduardo|Mukherjee, Bhramar|Kuick, Rork|Raskin, Leon|Misek, David E|Taylor, Jeremy M G|Giordano, Thomas J|Hanash, Samir M|Fearon, Eric R|Rennert, Gad|Gruber, Stephen B
PMID: 19351759
Journal: Int J Cancer. 2009 Jul 1;125(1):158-64.
Title: Somatic alterations, metabolizing genes and smoking in rectal cancer.
Author: Curtin, Karen|Samowitz, Wade S|Wolff, Roger K|Herrick, Jennifer|Caan, Bette J|Slattery, Martha L
PMID: 19358278
Journal: Int J Oncol. 2009 May;34(5):1313-8.
Title: A novel germline mutation of hMLH1 in a Korean hereditary non-polyposis colorectal cancer family.
Author: Kim, Ki-Hwan|Kim, Ju-Young|Oh, Se-Ig|Baik, Haing-Woon|Kang, Dong-Wook|Jung, Sung-Hee|Rho, Jeong-Hoon|Hwang, In-Taek
PMID: 19360343
Journal: Curr Protoc Hum Genet. 2009 Apr;Chapter 10:Unit 10.12.
Title: Genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC).
Author: Hegde, Madhuri R|Roa, Benjamin B
PMID: 19360696
Journal: Genet Test Mol Biomarkers. 2009 Apr;13(2):193-7.
Title: I219V polymorphism in hMLH1 gene in patients affected with ulcerative colitis.
Author: Vietri, Maria Teresa|Riegler, Gabriele|De Paola, Marialaura|Simeone, Serena|Boggia, Maria|Improta, Alessia|Parisi, Mariarita|Molinari, Anna Maria|Cioffi, Michele
PMID: 19371218
Journal: Clin Cancer Res. 2009 May 1;15(9):3156-62.
Title: Utility of p16 immunohistochemistry for the identification of Lynch syndrome.
Author: Paya, Artemio|Alenda, Cristina|Perez-Carbonell, Lucia|Rojas, Estefania|Soto, Jose-Luis|Guillen, Carmen|Castillejo, Adela|Barbera, Victor M|Carrato, Alfredo|Castells, Antoni|Llor, Xavier|Andreu, Montserrat|Koh, Jim|Enders, Greg H|Benlloch, Susana|Jover, Ro
PMID: 19383812
Journal: Int J Biol Markers. 2009 Jan-Mar;24(1):57-62.
Title: Gene-specific methylation: potential markers for colorectal cancer.
Author: Prabhu, Jyothi S|Korlimarla, Aruna|Banerjee, Arindam|Wani, Shivangi|K, Payal|Sahoo, Rashmita
PMID: 19404924
Journal: Eur J Surg Oncol. 2009 Oct;35(10):1128-30.
Title: A new mutation in Muir-Torre syndrome associated with familiar transmission of different gastrointestinal adenocarcinomas.
Author: Tanyi, M|Olasz, J|Lukacs, G|Tanyi, J L|Toth, L|Antal-Szalmas, P|Ress, Z|Buban, T|Andras, C|Damjanovich, L
PMID: 19423266
Journal: Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1599-609.
Title: MutL-homolog 1 expression and risk of incident, sporadic colorectal adenoma: search for prospective biomarkers of risk for colorectal cancer.
Author: Sidelnikov, Eduard|Bostick, Roberd M|Flanders, W Dana|Long, Qi|Cohen, Vaunita L|Dash, Chiranjeev|Seabrook, March E|Fedirko, Veronika
PMID: 19423536
Journal: Int J Oncol. 2009 Jun;34(6):1541-7.
Title: Analysis of a correlation between the BRAF V600E mutation and abnormal DNA mismatch repair in patients with sporadic endometrial cancer.
Author: Kawaguchi, Makiko|Yanokura, Megumi|Banno, Kouji|Kobayashi, Yusuke|Kuwabara, Yoshiko|Kobayashi, Maya|Nomura, Hiroyuki|Hirasawa, Akira|Susumu, Nobuyuki|Aoki, Daisuke
PMID: 19424571
Journal: Oncol Rep. 2009 Jun;21(6):1577-83.
Title: Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability.
Author: Nakagawa, Hitoshi|Nagasaka, Takeshi|Cullings, Harry M|Notohara, Kenji|Hoshijima, Naoko|Young, Joanne|Lynch, Henry T|Tanaka, Noriaki|Matsubara, Nagahide
PMID: 19424639
Journal: Mod Pathol. 2009 Jul;22(7):922-32.
Title: SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Firestein, Ron|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Hazra, Aditi|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19430421
Journal: PLoS One. 2009;4(5):e5517.
Title: Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans.
Author: Maddocks, Oliver D K|Short, Abigail J|Donnenberg, Michael S|Bader, Scott|Harrison, David J
PMID: 19436735
Journal: Pathol Res Pract. 2009;205(11):801-6.
Title: Serous oligocystic adenoma (SOIA) of the pancreas--first reported case of a genetically fixed association in a patient with hereditary non-polyposis colorectal cancer (HNPCC).
Author: Petersen, M|Evert, M|Schneider-Stock, R|Pross, M|Ruschoff, J|Roessner, A|Lippert, H|Meyer, F
PMID: 19446403
Journal: Int J Cancer. 2009 Sep 1;125(5):1231-7.
Title: HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers.
Author: Walsh, Michael D|Dent, Owen F|Young, Joanne P|Wright, Caroline M|Barker, Melissa A|Leggett, Barbara A|Bokey, Les|Chapuis, Pierre H|Jass, Jeremy R|Macdonald, Graeme A
PMID: 19462453
Journal: Sao Paulo Med J. 2009 Jan;127(1):46-51.
Title: Mismatch repair genes in Lynch syndrome: a review.
Author: Silva, Felipe Cavalcanti Carneiro da|Valentin, Mev Dominguez|Ferreira, Fabio de Oliveira|Carraro, Dirce Maria|Rossi, Benedito Mauro
PMID: 19466295
Journal: Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title: DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Baba, Yoshifumi|Kirkner, Gregory J|Chen, Li|Gokhale, Sumita|Hazra, Aditi|Spiegelman, Donna|Giovannucci, Edward L|Jaenisch, Rudolf|Fuchs, Charles S|Ogino, Shuji
PMID: 19470733
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2009 Jun;26(3):314-7.
Title: [Association of MLH1 gene 415G/C polymorphism with colorectal cancer in Chinese].
Author: Tao, Wei-ping|Hu, Sheng|Feng, Jue-ping|Xie, Yi-shan
PMID: 19504447
Journal: Gynecol Oncol. 2009 Sep;114(3):486-90.
Title: Prospective evaluation of DNA mismatch repair protein expression in primary endometrial cancer.
Author: Backes, Floor J|Leon, Marino E|Ivanov, Iouri|Suarez, Adrian|Frankel, Wendy L|Hampel, Heather|Fowler, Jeffrey M|Copeland, Larry J|O'Malley, David M|Cohn, David E
PMID: 19515405
Journal: Fam Cancer. 2009;8(4):421-9.
Title: Screening for germline mutations of MLH1, MSH2, MSH6 and PMS2 genes in Slovenian colorectal cancer patients: implications for a population specific detection strategy of Lynch syndrome.
Author: Berginc, Gasper|Bracko, Matej|Ravnik-Glavac, Metka|Glavac, Damjan
PMID: 19526325
Journal: Mol Cancer Ther. 2009 Jul;8(7):1964-73.
Title: Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.
Author: Crea, Francesco|Giovannetti, Elisa|Cortesi, Filippo|Mey, Valentina|Nannizzi, Sara|Gallegos Ruiz, Marielle I|Ricciardi, Simona|Del Tacca, Mario|Peters, Godefridus J|Danesi, Romano
PMID: 19531575
Journal: Adv Anat Pathol. 2009 Mar;16(2):79-91.
Title: Pathologic features and biologic importance of colorectal serrated polyps.
Author: Vakiani, Efsevia|Yantiss, Rhonda K
PMID: 19550369
Journal: J Med Genet. 2009 Dec;46(12):793-802.
Title: Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer.
Author: Hitchins, M P|Ward, R L
PMID: 19564652
Journal: Dis Colon Rectum. 2009 Jul;52(7):1304-11.
Title: A comparison of colon and rectal somatic DNA alterations.
Author: Slattery, Martha L|Curtin, Karen|Wolff, Roger K|Boucher, Kenneth M|Sweeney, Carol|Edwards, Sandra|Caan, Bette J|Samowitz, Wade
PMID: 19571709
Journal: Int J Oncol. 2009 Aug;35(2):321-7.
Title: Chromosomally and microsatellite stable colorectal carcinomas without the CpG island methylator phenotype in a molecular classification.
Author: Ostwald, Christiane|Linnebacher, Michael|Weirich, Volker|Prall, Friedrich
PMID: 19578746
Journal: Oncol Rep. 2009 Aug;22(2):265-71.
Title: Differences in expression between transcripts using alternative promoters of hMLH1 gene and their correlation with microsatellite instability.
Author: Takahashi, Ryosuke|Nagai, Keiichi
PMID: 19578765
Journal: Ann Surg Oncol. 2009 Oct;16(10):2918-25.
Title: Mitochondrial genomic instability in colorectal cancer: no correlation to nuclear microsatellite instability and allelic deletion of hMSH2, hMLH1, and p53 genes, but prediction of better survival for Dukes' stage C disease.
Author: Tsai, Ming-Hong|Fang, Woei-Horng|Lin, Shu-Wha|Yen, Sou-Jhy|Chou, Shao-Jiun|Yang, Ya-Chien
PMID: 19582509
Journal: Mol Carcinog. 2009 Nov;48(11):989-94.
Title: MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.
Author: Curtin, Karen|Samowitz, Wade S|Wolff, Roger K|Caan, Bette J|Ulrich, Cornelia M|Potter, John D|Slattery, Martha L
PMID: 19582761
Journal: J Gastroenterol. 2009;44(10):1036-45.
Title: Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender.
Author: Umeto, Harue|Yoshida, Tsutomu|Araki, Kayo|Yagishita, Hiroko|Mikami, Tetuo|Okayasu, Isao
PMID: 19590931
Journal: Cancer Genet Cytogenet. 2009 Aug;193(1):63-6.
Title: The TP53 gene promoter is not methylated in families suggestive of Li-Fraumeni syndrome with no germline TP53 mutations.
Author: Finkova, Alena|Vazna, Alzbeta|Hrachovina, Ondrej|Bendova, Sarka|Prochazkova, Kamila|Sedlacek, Zdenek
PMID: 19602465
Journal: Hepatogastroenterology. 2009 May-Jun;56(91-92):672-6.
Title: Effectiveness of each Bethesda marker in defining microsatellite instability when screening for Lynch syndrome.
Author: Sinn, Dong Hyun|Chang, Dong Kyung|Kim, Young-Ho|Rhee, Poong-Lyul|Kim, Jae J|Kim, Dae Shick|Park, Cheol Keun|Kim, Jong Won|Yun, Seong Hyeon|Lee, Woo-Yong|Chun, Ho-Kyung|Rhee, Jong Chul
PMID: 19621678
Journal: Hepatogastroenterology. 2009 May-Jun;56(91-92):677-81.
Title: Proximal shift in the distribution of adenomatous polyps in Korea over the past ten years.
Author: Park, Soo Young|Kim, Byung Chang|Shin, Sung Jae|Lee, Sang Kil|Kim, Tae Il|Kim, Won Ho
PMID: 19621679
Journal: Hepatogastroenterology. 2009 May-Jun;56(91-92):899-904.
Title: Analysis of microsatellite instability, protein expression and methylation status of hMLH1 and hMSH2 genes in gastric carcinomas.
Author: Gu, Mijin|Kim, DongSun|Bae, YoungKyung|Choi, JoonHyuk|Kim, SangWoon|Song, SunKyo
PMID: 19621725
Journal: Gastroenterology. 2009 Nov;137(5):1621-7.
Title: Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome.
Author: Stoffel, Elena|Mukherjee, Bhramar|Raymond, Victoria M|Tayob, Nabihah|Kastrinos, Fay|Sparr, Jennifer|Wang, Fei|Bandipalliam, Prathap|Syngal, Sapna|Gruber, Stephen B
PMID: 19622357
Journal: Clin Chem. 2009 Sep;55(9):1711-8.
Title: Nonfluorescent denaturing HPLC-based primer-extension method for allele-specific expression: application to analysis of mismatch repair genes.
Author: Aceto, Gitana M|De Lellis, Laura|Catalano, Teresa|Veschi, Serena|Radice, Paolo|Di Iorio, Angelo|Mariani-Costantini, Renato|Cama, Alessandro|Curia, Maria Cristina
PMID: 19628660
Journal: J Clin Pathol. 2009 Aug;62(8):679-84.
Title: Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma.
Author: Garg, K|Soslow, R A
PMID: 19638537
Journal: Cancer Res. 2009 Aug 15;69(16):6423-9.
Title: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Author: Edwards, Robert A|Witherspoon, Mavee|Wang, Kehui|Afrasiabi, Kambiz|Pham, Trang|Birnbaumer, Lutz|Lipkin, Steven M
PMID: 19638594
Journal: Int J Oncol. 2009 Sep;35(3):631-40.
Title: MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells.
Author: Imesch, Patrick|Dedes, Konstantin J|Furlato, Michele|Fink, Daniel|Fedier, Andre
PMID: 19639184
Journal: Fam Cancer. 2009;8(4):483-7.
Title: Are prediction models for Lynch syndrome valid for probands with endometrial cancer?
Author: Backes, Floor J|Hampel, Heather|Backes, Katherine A|Vaccarello, Luis|Lewandowski, George|Bell, Jeffrey A|Reid, Gary C|Copeland, Larry J|Fowler, Jeffrey M|Cohn, David E
PMID: 19642020
Journal: J Biomed Biotechnol. 2009;2009:369129.
Title: Clinical significance of epigenetic inactivation of hMLH1 and BRCA1 in Tunisian patients with invasive breast carcinoma.
Author: Karray-Chouayekh, Sondes|Trifa, Fatma|Khabir, Abdelmajid|Boujelbane, Nouredine|Sellami-Boudawara, Tahia|Daoud, Jamel|Frikha, Mounir|Gargouri, Ali|Mokdad-Gargouri, Raja
PMID: 19644562
Journal: Cancer. 2009 Nov 1;115(21):4946-58.
Title: Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer.
Author: Horst, David|Budczies, Jan|Brabletz, Thomas|Kirchner, Thomas|Hlubek, Falk
PMID: 19658179
Journal: Clin Genet. 2009 Jul;76(1):1-18.
Title: Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications.
Author: Lynch, H T|Lynch, P M|Lanspa, S J|Snyder, C L|Lynch, J F|Boland, C R
PMID: 19659756
Journal: Cancer Genet Cytogenet. 2009 Sep;193(2):71-7.
Title: A MLH1 polymorphism that increases cancer risk is associated with better outcome in sporadic colorectal cancer.
Author: Nejda, Nargisse|Iglesias, Daniel|Moreno Azcoita, Mariano|Medina Arana, Vicente|Gonzalez-Aguilera, Juan J|Fernandez-Peralta, Antonia M
PMID: 19665066
Journal: Fam Cancer. 2009;8(4):289-98.
Title: Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing.
Author: Marafie, Makia J|Al-Awadi, Sadiqa|Al-Mosawi, Fatemah|Elshafey, Alaa|Al-Ali, Waleed|Al-Mulla, Fahd
PMID: 19669601
Journal: Cancer Causes Control. 2009 Nov;20(9):1763-8.
Title: Microsatellite instability and survival in rectal cancer.
Author: Samowitz, Wade S|Curtin, Karen|Wolff, Roger K|Tripp, Sheryl R|Caan, Bette J|Slattery, Martha L
PMID: 19669908
Journal: Zhonghua Yi Xue Za Zhi. 2009 May 26;89(20):1377-81.
Title: [Expression of cyclooxygenase-2 and relationship with mismatch repair gene and microsatellite instability in hereditary non-polyposis colorectal cancer].
Author: Zhang, Ying-hui|Sheng, Jian-qiu|Geng, Hong-gang|Han, Min|Huang, Ji-sheng|Mu, Hong|Han, Wen-liang|Chen, Ji-gui|Niu, Hong-li|Li, Ai-qin|Wu, Zi-tao|Li, Shi-rong
PMID: 19671325
Journal: Fam Cancer. 2009;8(4):501-4.
Title: Epitope-positive truncating MLH1 mutation and loss of PMS2: implications for IHC-directed genetic testing for Lynch syndrome.
Author: Zighelboim, Israel|Powell, Matthew A|Babb, Sheri A|Whelan, Alison J|Schmidt, Amy P|Clendenning, Mark|Senter, Leigha|Thibodeau, Stephen N|de la Chapelle, Albert|Goodfellow, Paul J
PMID: 19672700
Journal: Fam Cancer. 2009;8(4):509-17.
Title: Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Author: Naruse, Hiromu|Ikawa, Noriko|Yamaguchi, Kiyoshi|Nakamura, Yusuke|Arai, Masami|Ishioka, Chikashi|Sugano, Kokichi|Tamura, Kazuo|Tomita, Naohiro|Matsubara, Nagahide|Yoshida, Teruhiko|Moriya, Yoshihiro|Furukawa, Yoichi
PMID: 19685281
Journal: Acta Med Port. 2009 May-Jun;22(3):207-14. Epub 2009 Jul 15.
Title: [Familial colorectal cancer type X: clinical, pathological and molecular characterization].
Author: Ferreira, Sara|Lage, Pedro|Sousa, Rita|Claro, Isabel|Francisco, Ines|Filipe, Bruno|Suspiro, Alexandra|Chaves, Paula|Rodrigues, Paula|Albuquerque, Cristina|Nobre Leitao, C
PMID: 19686620
Journal: Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title: A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author: Nosho, Katsuhiko|Kure, Shoko|Irahara, Natsumi|Shima, Kaori|Baba, Yoshifumi|Spiegelman, Donna|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19686742
Journal: Fam Cancer. 2009;8(4):519-23.
Title: Cancer risk in a cohort of subjects carrying a single mismatch repair gene mutation.
Author: Stupart, D A|Goldberg, P A|Algar, U|Ramesar, R
PMID: 19688281
Journal: Cancer Res. 2009 Sep 1;69(17):7053-61.
Title: Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases.
Author: Mueller, James|Gazzoli, Isabella|Bandipalliam, Prathap|Garber, Judy E|Syngal, Sapna|Kolodner, Richard D
PMID: 19690142
Journal: J Clin Invest. 2009 Sep;119(9):2714-24.
Title: Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.
Author: Fu, Zheng|Regan, Kevin|Zhang, Lizhi|Muders, Michael H|Thibodeau, Stephen N|French, Amy|Wu, Yanhong|Kaufmann, Scott H|Lingle, Wilma L|Chen, Junjie|Tindall, Donald J
PMID: 19690386
Journal: Fam Cancer. 2009;8(4):489-500.
Title: Functional characterization of rare missense mutations in MLH1 and MSH2 identified in Danish colorectal cancer patients.
Author: Christensen, Lise Lotte|Kariola, Reetta|Korhonen, Mari K|Wikman, Friedrik P|Sunde, Lone|Gerdes, Anne-Marie|Okkels, Henrik|Brandt, Carsten A|Bernstein, Inge|Hansen, Thomas V O|Hagemann-Madsen, Rikke|Andersen, Claus L|Nystrom, Minna|Orntoft, Torben F
PMID: 19697156
Journal: Hered Cancer Clin Pract. 2009 Aug 23;7(1):14.
Title: Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario.
Author: Choi, Yun-Hee|Cotterchio, Michelle|McKeown-Eyssen, Gail|Neerav, Monga|Bapat, Bharati|Boyd, Kevin|Gallinger, Steven|McLaughlin, John|Aronson, Melyssa|Briollais, Laurent
PMID: 19698169
Journal: Am J Surg Pathol. 2009 Nov;33(11):1639-45.
Title: Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel.
Author: Shia, Jinru|Tang, Laura H|Vakiani, Efsevia|Guillem, Jose G|Stadler, Zsofia K|Soslow, Robert A|Katabi, Nora|Weiser, Martin R|Paty, Philip B|Temple, Larissa K|Nash, Garrett M|Wong, W Douglas|Offit, Kenneth|Klimstra, David S
PMID: 19701074
Journal: Neoplasma. 2009;56(6):500-7.
Title: Germline variants of the promyelocytic leukemia tumor suppressor gene in patients with familial cancer.
Author: Plevova, P|Walczyskova, S|Jeziskova, I|Jurckova, N|Krepelova, A|Puchmajerova, A|Pavlikova, K|Foretova, L|Zapletalova, J|Silhanova, E
PMID: 19728758
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Aug;34(8):757-61.
Title: [Clinicopathologic characteristics, diagnosis, and treatment of 30 patients with hereditary nonpolyposis colorectal cancer].
Author: Liu, Heli|Yan, Zhongshu|Liao, Guoqing|Yin, Hongling|Xie, Xiaoyong
PMID: 19734583
Journal: Cancer Prev Res (Phila). 2009 Sep;2(9):814-22.
Title: Concordant DNA methylation in synchronous colorectal carcinomas.
Author: Konishi, Kazuo|Shen, Lanlan|Jelinek, Jaroslav|Watanabe, Yoshiyuki|Ahmed, Saira|Kaneko, Kazuhiro|Kogo, Mari|Takano, Toshihumi|Imawari, Michio|Hamilton, Stanley R|Issa, Jean-Pierre J
PMID: 19737982
Journal: Genet Med. 2009 Nov;11(11):812-7.
Title: Immunohistochemistry staining for the mismatch repair proteins in the clinical care of patients with colorectal cancer.
Author: South, Christopher D|Yearsley, Martha|Martin, Edward|Arnold, Mark|Frankel, Wendy|Hampel, Heather
PMID: 19752738
Journal: Carcinogenesis. 2009 Nov;30(11):1923-6.
Title: Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.
Author: Itano, Osamu|Yang, Kan|Fan, Kunhua|Kurihara, Naoto|Shinozaki, Hiroharu|Abe, Sadanori|Jin, Bo|Gravaghi, Claudia|Edelmann, Winfried|Augenlicht, Leonard|Kopelovich, Levy|Kucherlapati, Raju|Lamprecht, Sergio|Lipkin, Martin
PMID: 19755659
Journal: Fam Cancer. 2009;8(4):533-9.
Title: A study on MSH2 and MLH1 mutations in hereditary nonpolyposis colorectal cancer families from the Basque Country, describing four new germline mutations.
Author: Martinez-Bouzas, Cristina|Beristain, Elena|Ojembarrena, Enrique|Errasti, Jose|Mujika, Karmele|Viguera, Noelia|Tejada, Maria Isabel
PMID: 19760518
Journal: J Int Med Res. 2009 Jul-Aug;37(4):1038-45.
Title: Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
Author: Kominami, K|Nagasaka, T|Cullings, H M|Hoshizima, N|Sasamoto, H|Young, J|Leggett, B A|Tanaka, N|Matsubara, N
PMID: 19761686
Journal: Exp Cell Res. 2009 Nov 1;315(18):3163-75.
Title: MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.
Author: Sun, Guoming|Jin, Shunqian|Baskaran, R
PMID: 19766113
Journal: Clin Cancer Res. 2009 Oct 1;15(19):6185-91.
Title: Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer.
Author: Lee, Bo Bin|Lee, Eun Ju|Jung, Eun Hyun|Chun, Ho-Kyung|Chang, Dong Kyoung|Song, Sang Yong|Park, Joobae|Kim, Duk-Hwan
PMID: 19773381
Journal: Int J Oncol. 2009 Nov;35(5):977-82.
Title: Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.
Author: Kawaguchi, Makiko|Banno, Kouji|Yanokura, Megumi|Kobayashi, Yusuke|Kishimi, Arisa|Ogawa, Seiji|Kisu, Iori|Nomura, Hiroyuki|Hirasawa, Akira|Susumu, Nobuyuki|Aoki, Daisuke
PMID: 19787250
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title: Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author: Kure, Shoko|Nosho, Katsuhiko|Baba, Yoshifumi|Irahara, Natsumi|Shima, Kaori|Ng, Kimmie|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19789368
Journal: Surg Oncol Clin N Am. 2009 Oct;18(4):611-24.
Title: The hMSH2 and hMLH1 genes in hereditary nonpolyposis colorectal cancer.
Author: Lynch, Patrick M
PMID: 19793569
Journal: Pathologe. 2009 Dec;30 Suppl 2:185-7.
Title: [Renal pelvic carcinoma: a different urothelial tumor?].
Author: Hofstadter, F
PMID: 19795126
Journal: Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title: Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Meyerhardt, Jeffrey A|Baba, Yoshifumi|Shima, Kaori|Glickman, Jonathan N|Ferrone, Cristina R|Mino-Kenudson, Mari|Tanaka, Noriko|Dranoff, Glenn|Giovannucci, Edward L|Fuchs, Charles S
PMID: 19825961
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3086-96.
Title: Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer.
Author: de Vogel, Stefan|Wouters, Kim A D|Gottschalk, Ralph W H|van Schooten, Frederik J|de Goeij, Anton F P M|de Bruine, Adriaan P|Goldbohm, Royle A|van den Brandt, Piet A|Weijenberg, Matty P|van Engeland, Manon
PMID: 19843671
Journal: APMIS. 2009 Nov;117(11):839-48.
Title: Differential expression of hMLH1 in sporadic human colorectal cancer tumors and distant metastases.
Author: Larsen, Nicolai Balle|Heiberg Engel, Peter Johan|Rasmussen, Merete|Rasmussen, Lene Juel
PMID: 19845535
Journal: Adv Anat Pathol. 2009 Nov;16(6):405-17.
Title: Colorectal cancer due to deficiency in DNA mismatch repair function: a review.
Author: Bellizzi, Andrew M|Frankel, Wendy L
PMID: 19851131
Journal: Rev Gastroenterol Mex. 2009;74(3):256-8.
Title: [Hereditary non-polyposis colorectal cancer associated with hereditary gastric cancer. A case report.].
Author: Castaneda-Argaiz, R|Gonzalez-Contreras, Q H|Medina-Franco, H|Rodriguez-Zentner, H A|Tapia-Cid de Leon, H|Vergara-Fernandez, O
PMID: 19858019
Journal: J Clin Oncol. 2009 Nov 20;27(33):5519-28.
Title: Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.
Author: Braun, Michael S|Richman, Susan D|Thompson, Lindsay|Daly, Catherine L|Meade, Angela M|Adlard, Julian W|Allan, James M|Parmar, Mahesh K B|Quirke, Philip|Seymour, Matthew T
PMID: 19858398
Journal: Clin Cancer Res. 2009 Nov 15;15(22):6912-20.
Title: Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells.
Author: Yan, Tao|Seo, Yuji|Kinsella, Timothy J
PMID: 19861440
Journal: Hered Cancer Clin Pract. 2009 Oct 28;7(1):16.
Title: Penetrance of HNPCC-related cancers in a retrolective cohort of 12 large Newfoundland families carrying a MSH2 founder mutation: an evaluation using modified segregation models.
Author: Kopciuk, Karen A|Choi, Yun-Hee|Parkhomenko, Elena|Parfrey, Patrick|McLaughlin, John|Green, Jane|Briollais, Laurent
PMID: 19863818
Journal: J Clin Oncol. 2009 Dec 10;27(35):5931-7.
Title: KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial.
Author: Richman, Susan D|Seymour, Matthew T|Chambers, Philip|Elliott, Faye|Daly, Catherine L|Meade, Angela M|Taylor, Graham|Barrett, Jennifer H|Quirke, Philip
PMID: 19884549
Journal: BMC Cancer. 2009 Nov 20;9:405.
Title: Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers.
Author: Zavodna, Katarina|Krivulcik, Tomas|Bujalkova, Maria Gerykova|Slamka, Tomas|Martinicky, David|Ilencikova, Denisa|Bartosova, Zdena
PMID: 19930554
Journal: World J Surg Oncol. 2009 Dec 8;7:94.
Title: Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report.
Author: Valenzuela, Cristian D|Moore, Harvey G|Huang, William C|Reich, Elsa W|Yee, Herman|Ostrer, Harry|Pachter, H Leon
PMID: 19995443
Journal: Ann Pathol. 2009 Dec;29(6):495-8.
Title: [Muir-Torre syndrome: rare association with duodenal carcinoma].
Author: Bacha, Dhouha|Deschamps, Lydia|Sauvanet, Alain|Couvelard, Anne
PMID: 20005439
Journal: Hered Cancer Clin Pract. 2009 Dec 23;7(1):17.
Title: Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management.
Author: Ramsoekh, Dewkoemar|Wagner, Anja|van Leerdam, Monique E|Dooijes, Dennis|Tops, Carli Mj|Steyerberg, Ewout W|Kuipers, Ernst J
PMID: 20028567
Journal: Tumori. 2009 Nov-Dec;95(6):731-8.
Title: Prognostic relevance of MLH1 and MSH2 mutations in hereditary non-polyposis colorectal cancer patients.
Author: Russo, Antonio|Sala, Paola|Alberici, Paola|Gazzoli, Isabella|Radice, Paolo|Montefusco, Claudia|Torrini, Margherita|Mareni, Cristina|Fornasarig, Mara|Santarosa, Manuela|Viel, Alessandra|Benatti, Piero|Pedroni, Monica|de Leon, Maurizio Ponz|Lucci-Cordisco,
PMID: 20210238
Journal: J Clin Aesthet Dermatol. 2009 Aug;2(8):30-2.
Title: Muir-torre syndrome: a case report.
Author: Higgins, Heather J|Voutsalath, Melissa|Holland, Jean M
PMID: 20729952
Journal: Clin Colon Rectal Surg. 2009 Nov;22(4):198-208.
Title: Inherited colorectal cancer syndromes.
Author: Gryfe, Robert
PMID: 21037810
Journal: Mol Med Rep. 2009 Nov-Dec;2(6):887-91.
Title: Colorectal cancer susceptibility associated with the hMLH1 V384D variant.
Author: Ohsawa, Tomonori|Sahara, Tomoko|Muramatsu, Shino|Nishimura, Yoji|Yathuoka, Toshimasa|Tanaka, Yoichi|Yamaguchi, Kensei|Ishida, Hideyuki|Akagi, Kiwamu
PMID: 21475916
Journal: J Med Genet. 2010 Feb;47(2):99-102.
Title: Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds.
Author: Grindedal, Eli Marie|Renkonen-Sinisalo, Laura|Vasen, Hans|Evans, Gareth|Sala, Paola|Blanco, Ignacio|Gronwald, Jacek|Apold, Jaran|Eccles, Diana M|Sanchez, Angel Alonso|Sampson, Julian|Jarvinen, Heikki J|Bertario, Lucio|Crawford, Gillian C|Stormorken, Astri
PMID: 19635727
Journal: Int J Cancer. 2010 Feb 15;126(4):930-9.
Title: Validation of predictive models for germline mutations in DNA mismatch repair genes in colorectal cancer.
Author: Monzon, Jose G|Cremin, Carol|Armstrong, Linlea|Nuk, Jennifer|Young, Sean|Horsman, Doug E|Garbutt, Kristy|Bajdik, Chris D|Gill, Sharlene
PMID: 19653273
Journal: J Cancer Res Clin Oncol. 2010 Jan;136(1):123-34.
Title: Comparative in silico analyses and experimental validation of novel splice site and missense mutations in the genes MLH1 and MSH2.
Author: Betz, Beate|Theiss, Stephan|Aktas, Murat|Konermann, Carolin|Goecke, Timm O|Moslein, Gabriela|Schaal, Heiner|Royer-Pokora, Brigitte
PMID: 19669161
Journal: Int J Colorectal Dis. 2010 Jan;25(1):63-9.
Title: Colorectal cancer in Iran: immunohistochemical profiles of four mismatch repair proteins.
Author: Molaei, Mahsa|Mansoori, Babak Khoshkrood|Ghiasi, Somayeh|Khatami, Fatemeh|Attarian, Hamid|Zali, MohammadReza
PMID: 19707776
Journal: Mol Carcinog. 2010 Jan;49(1):94-103.
Title: Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model.
Author: Borinstein, Scott C|Conerly, Melissa|Dzieciatkowski, Slavomir|Biswas, Swati|Washington, M Kay|Trobridge, Patty|Henikoff, Steve|Grady, William M
PMID: 19777566
Journal: Curr Opin Gastroenterol. 2010 Jan;26(1):47-52.
Title: Recent insights into the pathogenesis of colorectal cancer.
Author: Goel, Ajay|Boland, Clement Richard
PMID: 19786869
Journal: Fam Cancer. 2010 Jun;9(2):131-9.
Title: Clinical and histomolecular endometrial tumor characterization of patients at-risk for Lynch syndrome in South of Brazil.
Author: Cossio, Silvia Liliana|Koehler-Santos, Patricia|Pessini, Suzana Arenhart|Monego, Heleuza|Edelweiss, Maria Isabel|Meurer, Luise|Errami, Abdellatif|Coffa, Jordy|Bock, Hugo|Saraiva-Pereira, Maria Luiza|Ashton-Prolla, Patricia|Prolla, Joao Carlos
PMID: 19821155
Journal: Clin Gastroenterol Hepatol. 2010 Feb;8(2):174-82.
Title: Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer.
Author: Engel, Christoph|Rahner, Nils|Schulmann, Karsten|Holinski-Feder, Elke|Goecke, Timm O|Schackert, Hans K|Kloor, Matthias|Steinke, Verena|Vogelsang, Holger|Moslein, Gabriela|Gorgens, Heike|Dechant, Stefan|von Knebel Doeberitz, Magnus|Ruschoff, Josef|Friedric
PMID: 19835992
Journal: Int J Cancer. 2010 Jun 15;126(12):3005-9.
Title: CHEK2 mutations and HNPCC-related colorectal cancer.
Author: Suchy, Janina|Cybulski, Cezary|Wokolorczyk, Dominika|Oszurek, Oleg|Gorski, Bohdan|Debniak, Tadeusz|Jakubowska, Anna|Gronwald, Jacek|Huzarski, Tomasz|Byrski, Tomasz|Dziuba, Ireneusz|Gogacz, Marek|Wisniowski, Rafal|Wandzel, Piotr|Banaszkiewicz, Zbigniew|Kur
PMID: 19876921
Journal: Fam Cancer. 2010 Jun;9(2):167-72.
Title: Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation.
Author: Bouzourene, Hanifa|Hutter, Pierre|Losi, Lorena|Martin, Patricia|Benhattar, Jean
PMID: 19949877
Journal: Med Oncol. 2010 Dec;27(4):1277-85.
Title: The effect of DNA mismatch repair (MMR) status on oxaliplatin-based first-line chemotherapy as in recurrent or metastatic colon cancer.
Author: Kim, Seung Tae|Lee, Jeeyun|Park, Se Hoon|Park, Joon Oh|Lim, Ho Yeong|Kang, Won Ki|Kim, Jin Yong|Kim, Young Ho|Chang, Dong Kyung|Rhee, Poong-Lyul|Kim, Dae Shick|Yun, Haeran|Cho, Yong Beom|Kim, Hee Cheol|Yun, Seong Hyeon|Chun, Ho-Kyung|Lee, Woo Yong|Park, Y
PMID: 19949897
Journal: Oncol Rep. 2010 Jan;23(1):191-7.
Title: CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients.
Author: Hiraki, Masatsugu|Kitajima, Yoshihiko|Nakafusa, Yuji|Nakamura, Jun|Hashiguchi, Kazuyoshi|Sumi, Kenji|Noshiro, Hirokazu|Miyazaki, Kohji
PMID: 19956881
Journal: Fam Cancer. 2010 Jun;9(2):151-4.
Title: Biallelic MYH germline mutations as cause of Muir-Torre syndrome.
Author: Guillen-Ponce, Carmen|Castillejo, Adela|Barbera, Victor M|Pascual-Ramirez, J Carlos|Andrada, Encarnacion|Castillejo, M Isabel|Guarinos, Carla|Molina-Garrido, M J|Carrato, Alfredo|Soto, J L
PMID: 19998059
Journal: Fam Cancer. 2010 Jun;9(2):155-66.
Title: Mismatch repair protein expression and colorectal cancer in Hispanics from Puerto Rico.
Author: De Jesus-Monge, Wilfredo E|Gonzalez-Keelan, Carmen|Zhao, Ronghua|Hamilton, Stanley R|Rodriguez-Bigas, Miguel|Cruz-Correa, Marcia
PMID: 20012372
Journal: Cancer Chemother Pharmacol. 2010 Sep;66(4):659-67.
Title: Clinical impact of microsatellite instability in colon cancer following adjuvant FOLFOX therapy.
Author: Kim, Seung Tae|Lee, Jeeyun|Park, Se Hoon|Park, Joon Oh|Lim, Ho Yeong|Kang, Won Ki|Kim, Jin Yong|Kim, Young Ho|Chang, Dong Kyung|Rhee, Poong-Lyul|Kim, Dae Shick|Yun, Haeran|Cho, Yong Beom|Kim, Hee Cheol|Yun, Seong Hyeon|Lee, Woo Yong|Chun, Ho-Kyung|Park, Y
PMID: 20033812
Journal: Gynecol Oncol. 2010 Mar;116(3):516-21.
Title: Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening.
Author: Walsh, Christine S|Blum, Audra|Walts, Ann|Alsabeh, Randa|Tran, Hang|Koeffler, H Phillip|Karlan, Beth Y
PMID: 20034658
Journal: Nutr Cancer. 2010;62(1):105-15.
Title: Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair.
Author: Dronamraju, Shridhar S|Coxhead, Jonathan M|Kelly, Seamus B|Mathers, John C
PMID: 20043265
Journal: Surgery. 2010 May;147(5):720-8.
Title: Taiwan hospital-based detection of Lynch syndrome distinguishes 2 types of microsatellite instabilities in colorectal cancers.
Author: Chang, Shih-Ching|Lin, Pei-Ching|Yang, Shung-Haur|Wang, Huann-Sheng|Liang, Wen-Yih|Lin, Jen-Kou
PMID: 20045164
Journal: Ann Surg Oncol. 2010 May;17(5):1435-41.
Title: Difference between proximal and distal microsatellite-unstable sporadic colorectal cancers: analysis of clinicopathological and molecular features and prognoses.
Author: Kim, Young-Ho|Min, Byung-Hoon|Kim, Sue Jin|Choi, Hyo Kyung|Kim, Kyoung-Mee|Chun, Ho-Kyung|Lee, Hyuk|Kim, Jin Yong|Chang, Dong Kyung|Son, Hee Jung|Rhee, Poong-Lyul|Rhee, Jong Chul|Kim, Jae J
PMID: 20049642
Journal: Hum Mutat. 2010 Mar;31(3):317-24.
Title: Microsatellite instability in the peripheral blood leukocytes of HNPCC patients.
Author: Coolbaugh-Murphy, Mary I|Xu, Jing-Ping|Ramagli, Louis S|Ramagli, Brian C|Brown, Barry W|Lynch, Patrick M|Hamilton, Stanley R|Frazier, Marsha L|Siciliano, Michael J
PMID: 20052760
Journal: Ann Surg Oncol. 2010 Jul;17(7):1767-76.
Title: Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas.
Author: Kim, Jin C|Choi, Jin S|Roh, Seon A|Cho, Dong H|Kim, Tae W|Kim, Yong S
PMID: 20077021
Journal: Gastroenterology. 2010 May;138(5):1854-62.
Title: Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency.
Author: Goel, Ajay|Xicola, Rosa M|Nguyen, Thuy-Phuong|Doyle, Brian J|Sohn, Vanessa R|Bandipalliam, Prathap|Rozek, Laura S|Reyes, Josep|Cordero, Carmen|Balaguer, Francesc|Castells, Antoni|Jover, Rodrigo|Andreu, Montserrat|Syngal, Sapna|Boland, C Richard|Llor, Xavi
PMID: 20102720
Journal: Nat Rev Clin Oncol. 2010 Mar;7(3):153-62.
Title: Microsatellite instability in colorectal cancer-the stable evidence.
Author: Vilar, Eduardo|Gruber, Stephen B
PMID: 20142816
Journal: Eur J Cancer. 2010 Apr;46(6):1041-8.
Title: Common variants in human CRC genes as low-risk alleles.
Author: Picelli, Simone|Zajac, Pawel|Zhou, Xiao-Lei|Edler, David|Lenander, Claes|Dalen, Johan|Hjern, Fredrik|Lundqvist, Nils|Lindforss, Ulrik|Pahlman, Lars|Smedh, Kennet|Tornqvist, Anders|Holm, Jorn|Janson, Martin|Andersson, Magnus|Ekelund, Susanne|Olsson, Louise
PMID: 20149637
Journal: J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):69-74.
Title: Epigenetic regulation of the ERbeta gene on the estrogen signal transfection pathway in colon cancer cells.
Author: Zhai, Ronglin|Wang, Guobin|Cai, Kailin|Tao, Kaixiong|Xu, Fei|Zhang, Wanli|Wang, Zhiyong
PMID: 20155458
Journal: Cancer Biomark. 2010;6(1):49-61.
Title: A ten markers panel provides a more accurate and complete microsatellite instability analysis in mismatch repair-deficient colorectal tumors.
Author: Agostini, Marco|Enzo, Maria Vittoria|Morandi, Luca|Bedin, Chiara|Pizzini, Silvia|Mason, Silvia|Bertorelle, Roberta|Urso, Emanuele|Mescoli, Claudia|Lise, Mario|Pucciarelli, Salvatore|Nitti, Donato
PMID: 20164541
Journal: Indian J Med Res. 2010 Jan;131:64-70.
Title: R659X mutation in the MLH1 gene in hereditary non-polyposis colorectal cancer(HNPCC) in an Indian extended family.
Author: Rajender, Singh|Pooja, Singh|Kumar, M V Kranthi|Karwasra, Rajendra|Singh, Lalji|Thangaraj, Kumarasamy
PMID: 20167975
Journal: Carcinogenesis. 2010 Jun;31(6):1003-9.
Title: Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Author: Ku, Ja-Lok|Shin, Young-Kyoung|Kim, Duck-Woo|Kim, Kyung-Hee|Choi, Jin-Sung|Hong, Sung-Hye|Jeon, You-Kyung|Kim, Sung-Hee|Kim, Hong-Sun|Park, Jae-Hyun|Kim, Il-Jin|Park, Jae-Gahb
PMID: 20176655
Journal: Minerva Gastroenterol Dietol. 2010 Mar;56(1):45-53.
Title: Lynch Syndrome/Hereditary Non-polyposis Colorectal Cancer (HNPCC).
Author: Stoffel, E M
PMID: 20190724
Journal: PLoS One. 2010 Feb 24;5(2):e9393.
Title: An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers.
Author: Goel, Ajay|Nagasaka, Takeshi|Hamelin, Richard|Boland, C Richard
PMID: 20195377
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title: PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Goessling, Wolfram|Chan, Andrew T|Ng, Kimmie|Chan, Jennifer A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20200425
Journal: Gastroenterology. 2010 Jun;138(7):2300-6.
Title: One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome.
Author: Vasen, Hans F A|Abdirahman, Mohamed|Brohet, Richard|Langers, Alexandra M J|Kleibeuker, Jan H|van Kouwen, Mariette|Koornstra, Jan Jacob|Boot, Henk|Cats, Annemieke|Dekker, Evelien|Sanduleanu, Silvia|Poley, Jan-Werner|Hardwick, James C H|de Vos Tot Nederveen
PMID: 20206180
Journal: Clin Cancer Res. 2010 Apr 1;16(7):2214-24.
Title: Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry.
Author: Walsh, Michael D|Buchanan, Daniel D|Cummings, Margaret C|Pearson, Sally-Ann|Arnold, Sven T|Clendenning, Mark|Walters, Rhiannon|McKeone, Diane M|Spurdle, Amanda B|Hopper, John L|Jenkins, Mark A|Phillips, Kerry D|Suthers, Graeme K|George, Jill|Goldblatt, Ja
PMID: 20215533
Journal: Dig Liver Dis. 2010 Sep;42(9):611-5.
Title: Location-related differences in sporadic microsatellite unstable colorectal cancer.
Author: Cho, Yong Kwon|Kim, Hee Cheol|Kim, Seok-Hyung|Park, Jun Ho|Yun, Hae-Ran|Cho, Yong Beom|Yun, Seong Hyeon|Lee, Woo Yong|Chun, Ho-Kyung
PMID: 20227930
Journal: Medicina (B Aires). 2010;70(1):31-6.
Title: [Detection of a founder mutation in an Argentine family with hereditary non polyposis colorectal cancer].
Author: Gomez, Laura|Adi, Jose|Ibarra, Jorge|Roque, Maria
PMID: 20228021
Journal: Dis Colon Rectum. 2010 Apr;53(4):450-9.
Title: Spectrum of MLH1 and MSH2 mutations in Chilean families with suspected Lynch syndrome.
Author: Alvarez, Karin|Hurtado, Claudia|Hevia, Montserrat A|Wielandt, Ana Maria|de la Fuente, Marjorie|Church, James|Carvallo, Pilar|Lopez-Kostner, Francisco
PMID: 20305446
Journal: Acta Oncol. 2010 Aug;49(6):797-804.
Title: Mismatch repair protein expression is an independent prognostic factor in sporadic colorectal cancer.
Author: Ohrling, Katarina|Edler, David|Hallstrom, Marja|Ragnhammar, Peter
PMID: 20307245
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):1022-32.
Title: Effects of calcium and vitamin D on MLH1 and MSH2 expression in rectal mucosa of sporadic colorectal adenoma patients.
Author: Sidelnikov, Eduard|Bostick, Roberd M|Flanders, W Dana|Long, Qi|Fedirko, Veronika|Shaukat, Aasma|Daniel, Carrie R|Rutherford, Robin E
PMID: 20332274
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Mar;13(3):216-8.
Title: [Mismatch repair gene hMLH1 A655G/A polymorphism and colorectal cancer].
Author: Song, Lei|Zhang, Xiao-mei|Wang, De-qiang|Li, Jin-tian|Ma, Guo-jian|Chen, Sen-qing|Zhou, Jian-nong
PMID: 20336543
Journal: Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1512-9.
Title: Impact of genomic methylation on radiation sensitivity of colorectal carcinoma.
Author: Hofstetter, Barbara|Niemierko, Andrzej|Forrer, Christian|Benhattar, Jean|Albertini, Veronica|Pruschy, Martn|Bosman, Fred T|Catapano, Carlo V|Ciernik, I Frank
PMID: 20338477
Journal: Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6982-7.
Title: Modulation of mismatch repair and genomic stability by miR-155.
Author: Valeri, Nicola|Gasparini, Pierluigi|Fabbri, Muller|Braconi, Chiara|Veronese, Angelo|Lovat, Francesca|Adair, Brett|Vannini, Ivan|Fanini, Francesca|Bottoni, Arianna|Costinean, Stefan|Sandhu, Sukhinder K|Nuovo, Gerard J|Alder, Hansjuerg|Gafa, Roberta|Calore,
PMID: 20351277
Journal: Fam Cancer. 2010 Sep;9(3):365-76.
Title: Analysis of mismatch repair gene mutations in Turkish HNPCC patients.
Author: Tunca, Berrin|Pedroni, Monica|Cecener, Gulsah|Egeli, Unal|Borsi, Enrica|Zorluoglu, Abdullah|Di Gregorio, Carmela|Yilmazlar, Tuncay|Yerci, Omer|de Leon, Maurizio Ponz
PMID: 20373145
Journal: Cancer Epidemiol. 2010 Jun;34(3):338-44.
Title: Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype.
Author: Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Misiak, Blazej|Gil, Justyna|Laczmanska, Izabela|Grzebieniak, Zygmunt|Sebzda, Tadeusz|Smigiel, Robert|Stembalska, Agnieszka|Sasiadek, Maria M
PMID: 20381446
Journal: Am J Clin Pathol. 2010 May;133(5):772-80.
Title: DNA mismatch repair deficiency in ampullary carcinoma: a morphologic and immunohistochemical study of 54 cases.
Author: Agaram, Narasimhan P|Shia, Jinru|Tang, Laura H|Klimstra, David S
PMID: 20395525
Journal: J Mol Diagn. 2010 Jul;12(4):433-40.
Title: Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma.
Author: Earle, Jonathan S L|Luthra, Rajyalakshmi|Romans, Angela|Abraham, Ronald|Ensor, Joe|Yao, Hui|Hamilton, Stanley R
PMID: 20413677
Journal: Eur J Cancer. 2010 Jul;46(10):1823-8.
Title: Molecular biology from bench-to-bedside - which colorectal cancer patients should be referred for genetic counselling and risk assessment.
Author: Jensen, Lars Henrik|Dysager, Lars|Lindebjerg, Jan|Kolvra, Steen|Byriel, Lene|Cruger, Dorthe Gylling
PMID: 20417091
Journal: Gastroenterology. 2010 Jun;138(6):2073-2087.e3.
Title: Microsatellite instability in colorectal cancer.
Author: Boland, C Richard|Goel, Ajay
PMID: 20420947
Journal: BMC Cancer. 2010 May 5;10:180.
Title: Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Author: van Roon, Eddy H J|van Puijenbroek, Marjo|Middeldorp, Anneke|van Eijk, Ronald|de Meijer, Emile J|Erasmus, Dianhdra|Wouters, Kim A D|van Engeland, Manon|Oosting, Jan|Hes, Frederik J|Tops, Carli M J|van Wezel, Tom|Boer, Judith M|Morreau, Hans
PMID: 20444249
Journal: BMC Cancer. 2010 May 14;10:207.
Title: Decreased transcription-coupled nucleotide excision repair capacity is associated with increased p53- and MLH1-independent apoptosis in response to cisplatin.
Author: Stubbert, Lawton J|Smith, Jennifer M|McKay, Bruce C
PMID: 20470425
Journal: Hered Cancer Clin Pract. 2010 May 21;8(1):5.
Title: MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.
Author: Talseth-Palmer, Bente A|McPhillips, Mary|Groombridge, Claire|Spigelman, Allan|Scott, Rodney J
PMID: 20487569
Journal: J Mol Diagn. 2010 Jul;12(4):498-504.
Title: Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome.
Author: Perez-Carbonell, Lucia|Alenda, Cristina|Paya, Artemio|Castillejo, Adela|Barbera, Victor M|Guillen, Carmen|Rojas, Estefania|Acame, Nuria|Gutierrez-Avino, Francisco J|Castells, Antoni|Llor, Xavier|Andreu, Montserrat|Soto, Jose-Luis|Jover, Rodrigo
PMID: 20489114
Journal: J Natl Compr Canc Netw. 2010 May;8(5):597-601.
Title: Point: justification for Lynch syndrome screening among all patients with newly diagnosed colorectal cancer.
Author: Hampel, Heather
PMID: 20495086
Journal: J Natl Compr Canc Netw. 2010 May;8(5):606-11.
Title: Counterpoint: implementing population genetic screening for Lynch Syndrome among newly diagnosed colorectal cancer patients--will the ends justify the means?
Author: Hall, Michael J
PMID: 20495087
Journal: Oncol Rep. 2010 Jul;24(1):37-46.
Title: Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line.
Author: Dibra, H K|Brown, J E|Hooley, P|Nicholl, I D
PMID: 20514442
Journal: J Clin Oncol. 2010 Jul 10;28(20):3380-7.
Title: Clinical relevance of microsatellite instability in colorectal cancer.
Author: de la Chapelle, Albert|Hampel, Heather
PMID: 20516444
Journal: Eur J Gastroenterol Hepatol. 2010 Aug;22(8):938-41.
Title: hMLH1 promoter methylation and JC virus T antigen presence in the tumor tissue of colorectal cancer Israeli patients of different ethnic groups.
Author: Niv, Yaron|Vilkin, Alex|Brenner, Baruch|Kendel, Yulia|Morgenstern, Sara|Levi, Zohar
PMID: 20531010
Journal: Am J Gastroenterol. 2010 Nov;105(11):2449-56.
Title: The gastrointestinal phenotype of germline biallelic mismatch repair gene mutations.
Author: Durno, Carol A|Holter, Spring|Sherman, Philip M|Gallinger, Steven
PMID: 20531397
Journal: Hum Mutat. 2010 Aug;31(8):975-82.
Title: Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.
Author: Kosinski, Jan|Hinrichsen, Inga|Bujnicki, Janusz M|Friedhoff, Peter|Plotz, Guido
PMID: 20533529
Journal: BMC Cancer. 2010 Jun 11;10:279.
Title: Hopefulness predicts resilience after hereditary colorectal cancer genetic testing: a prospective outcome trajectories study.
Author: Ho, Samuel M Y|Ho, Judy W C|Bonanno, George A|Chu, Annie T W|Chan, Emily M S
PMID: 20537192
Journal: Genes Chromosomes Cancer. 2010 Aug;49(8):746-59.
Title: Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability.
Author: Albuquerque, Cristina|Baltazar, Celia|Filipe, Bruno|Penha, Filipa|Pereira, Teresa|Smits, Ron|Cravo, Marilia|Lage, Pedro|Fidalgo, Paulo|Claro, Isabel|Rodrigues, Paula|Veiga, Isabel|Ramos, Jose Silva|Fonseca, Isabel|Leitao, Carlos Nobre|Fodde, Riccardo
PMID: 20544848
Journal: Ann Surg Oncol. 2010 Nov;17(11):2839-46.
Title: Absence of hMLH1 or hMSH2 expression as a stage-dependent prognostic factor in sporadic colorectal cancers.
Author: Park, Ji Won|Chang, Hee Jin|Park, Sohee|Kim, Byung Chang|Kim, Dae Yong|Baek, Ji-Yeon|Kim, Sun Young|Oh, Jae Hwan|Choi, Hyo Seong|Park, Sung Chan|Jeong, Seung-Yong
PMID: 20549564
Journal: Vopr Onkol. 2010;56(2):152-5.
Title: [Microsatellite instability of bilateral breast carcinomas is not linked to down-regulated expression of DNA mismatch repair genes].
Author: Kuligina, E Sh|Morreau, N|Imianitov, E N
PMID: 20552889
Journal: Hum Pathol. 2010 Oct;41(10):1387-96.
Title: Interobserver variability in the evaluation of mismatch repair protein immunostaining.
Author: Klarskov, Louise|Ladelund, Steen|Holck, Susanne|Roenlund, Karina|Lindebjerg, Jan|Elebro, Jacob|Halvarsson, Britta|von Salome, Jenny|Bernstein, Inge|Nilbert, Mef
PMID: 20573374
Journal: J Med Genet. 2010 Sep;47(9):579-85.
Title: Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers.
Author: Sjursen, Wenche|Haukanes, Bjorn Ivar|Grindedal, Eli Marie|Aarset, Harald|Stormorken, Astrid|Engebretsen, Lars F|Jonsrud, Christoffer|Bjornevoll, Inga|Andresen, Per Arne|Ariansen, Sarah|Lavik, Liss Anne S|Gilde, Bodil|Bowitz-Lothe, Inger Marie|Maehle, Lovi
PMID: 20587412
Journal: Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S207-12.
Title: Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly.
Author: Arai, Tomio|Kasahara, Ichiro|Sawabe, Motoji|Honma, Naoko|Aida, Junko|Tabubo, Kaiyo
PMID: 20590835
Journal: J Med Genet. 2010 Jul;47(7):464-70.
Title: Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
Author: van der Post, R S|Kiemeney, L A|Ligtenberg, M J L|Witjes, J A|Hulsbergen-van de Kaa, C A|Bodmer, D|Schaap, L|Kets, C M|van Krieken, J H J M|Hoogerbrugge, N
PMID: 20591884
Journal: J Gastrointestin Liver Dis. 2010 Jun;19(2):155-9.
Title: MMR gene expression pattern in sporadic colorectal cancer.
Author: Ioana, Mihai|Angelescu, Cristina|Burada, Florin|Mixich, Francisc|Riza, Anca|Dumitrescu, Theodor|Alexandru, Dragos|Ciurea, Tudorel|Cruce, Mihai|Saftoiu, Adrian
PMID: 20593048
Journal: Health Technol Assess. 2010 Jun;14(32):1-206.
Title: Chemoprevention of colorectal cancer: systematic review and economic evaluation.
Author: Cooper, K|Squires, H|Carroll, C|Papaioannou, D|Booth, A|Logan, R F|Maguire, C|Hind, D|Tappenden, P
PMID: 20594533
Journal: Pathology. 2010;42(5):409-13.
Title: Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma.
Author: Hall, Geoffrey|Clarkson, Adele|Shi, Amanda|Langford, Eileen|Leung, Helen|Eckstein, Robert P|Gill, Anthony J
PMID: 20632815
Journal: Pathology. 2010;42(5):414-20.
Title: DNA mismatch repair enzyme immunohistochemistry in colorectal cancer: a comparison of biopsy and resection material.
Author: Kumarasinghe, Anuttara Panchali|de Boer, Bastiaan|Bateman, Adrian C|Kumarasinghe, Marian Priyanthi
PMID: 20632816
Journal: Fam Cancer. 2010 Dec;9(4):589-94.
Title: MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
Author: Lefevre, Jeremie H|Colas, Chrystelle|Coulet, Florence|Bonilla, Carolina|Mourra, Najat|Flejou, Jean-Francois|Tiret, Emmanuel|Bodmer, Walter|Soubrier, Florent|Parc, Yann
PMID: 20640893
Journal: World J Gastroenterol. 2010 Jul 28;16(28):3553-60.
Title: Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas.
Author: Psofaki, Vasiliki|Kalogera, Chryssoula|Tzambouras, Nikolaos|Stephanou, Dimitrios|Tsianos, Epameinondas|Seferiadis, Konstantin|Kolios, Georgios
PMID: 20653064
Journal: Clin Gastroenterol Hepatol. 2010 Nov;8(11):966-71.
Title: Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer.
Author: Goel, Ajay|Nagasaka, Takeshi|Spiegel, Jennifer|Meyer, Richard|Lichliter, Warren E|Boland, C Richard
PMID: 20655395
Journal: Cancer Prev Res (Phila). 2010 Aug;3(8):910-6.
Title: Estrogen stimulates the expression of mismatch repair gene hMLH1 in colonic epithelial cells.
Author: Jin, Peng|Lu, Xiao-juan|Sheng, Jian-qiu|Fu, Lei|Meng, Xiao-ming|Wang, Xin|Shi, Tai-ping|Li, Shi-rong|Rao, Jianyu
PMID: 20663978
Journal: Cancer. 2010 Nov 1;116(21):4965-72.
Title: Microsatellite instability among individuals of Hispanic origin with colorectal cancer.
Author: Gupta, Samir|Ashfaq, Raheela|Kapur, Payal|Afonso, Bianca B|Nguyen, Thuy-Phuong T|Ansari, Faryal|Boland, C Richard|Goel, Ajay|Rockey, Don C
PMID: 20665498
Journal: Gut. 2010 Oct;59(10):1369-77.
Title: The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease.
Author: Woods, M O|Younghusband, H B|Parfrey, P S|Gallinger, S|McLaughlin, J|Dicks, E|Stuckless, S|Pollett, A|Bapat, B|Mrkonjic, M|de la Chapelle, A|Clendenning, M|Thibodeau, S N|Simms, M|Dohey, A|Williams, P|Robb, D|Searle, C|Green, J S|Green, R C
PMID: 20682701
Journal: J Biol Chem. 2010 Oct 22;285(43):33010-7.
Title: Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
Author: Qi, Yongmei|Schoene, Norberta W|Lartey, Frederick M|Cheng, Wen-Hsing
PMID: 20709753
Journal: Methods Mol Biol. 2010;653:193-205.
Title: Mutational screening of hMLH1 and hMSH2 that confer inherited colorectal cancer susceptibility using denature gradient gel electrophoresis (DGGE).
Author: Liu, Tao
PMID: 20721744
Journal: J Zhejiang Univ Sci B. 2010 Sep;11(9):647-53.
Title: Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients.
Author: Huang, Yan-qin|Yuan, Ying|Ge, Wei-ting|Hu, Han-guang|Zhang, Su-zhan|Zheng, Shu
PMID: 20803768
Journal: Pathologe. 2010 Oct;31 Suppl 2:268-73.
Title: [Microsatellite instability. A new predictive marker (?)].
Author: Dietmaier, W
PMID: 20824433
Journal: Folia Med (Plovdiv). 2010 Apr-Jun;52(2):22-30.
Title: DNA methylation in patients with colorectal cancer--correlation with some clinical and morphological features and with local tumour invasion.
Author: Mirchev, Milko B|Kahl, Philip|Friedrichs, Nicolaus|Kotzev, Iskren A|Buettner, Reinhard
PMID: 20836393
Journal: J Gastrointest Surg. 2010 Oct;14(10):1521-8.
Title: Relationship of EMAST and microsatellite instability among patients with rectal cancer.
Author: Devaraj, Bikash|Lee, Aaron|Cabrera, Betty L|Miyai, Katsumi|Luo, Linda|Ramamoorthy, Sonia|Keku, Temitope|Sandler, Robert S|McGuire, Kathleen L|Carethers, John M
PMID: 20844976
Journal: Leuk Lymphoma. 2010 Oct;51(10):1875-86.
Title: Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas.
Author: Reiss, Cora|Haneke, Torsten|Volker, Hans-Ulrich|Spahn, Martin|Rosenwald, Andreas|Edelmann, Winfried|Kneitz, Burkhard
PMID: 20858091
Journal: Cancer Res. 2010 Oct 1;70(19):7379-91.
Title: MLH1 founder mutations with moderate penetrance in Spanish Lynch syndrome families.
Author: Borras, Ester|Pineda, Marta|Blanco, Ignacio|Jewett, Ethan M|Wang, Fei|Teule, Alex|Caldes, Trinidad|Urioste, Miguel|Martinez-Bouzas, Cristina|Brunet, Joan|Balmana, Judith|Torres, Asuncion|Ramon y Cajal, Teresa|Sanz, Judit|Perez-Cabornero, Lucia|Castellvi-B
PMID: 20858721
Journal: Hum Pathol. 2010 Dec;41(12):1749-57.
Title: Tumor necrosis is a new promising prognostic factor in colorectal cancer.
Author: Pollheimer, Marion J|Kornprat, Peter|Lindtner, Richard A|Harbaum, Lars|Schlemmer, Andrea|Rehak, Peter|Langner, Cord
PMID: 20869096
Journal: Adv Genet. 2010;70:309-23.
Title: Epigenetic drivers of genetic alterations.
Author: Toyota, Minoru|Suzuki, Hiromu
PMID: 20920753
Journal: Clin Cancer Res. 2010 Nov 15;16(22):5402-13.
Title: MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer.
Author: Giraldez, Maria Dolores|Balaguer, Francesc|Bujanda, Luis|Cuatrecasas, Miriam|Munoz, Jenifer|Alonso-Espinaco, Virginia|Larzabal, Mikel|Petit, Anna|Gonzalo, Victoria|Ocana, Teresa|Moreira, Leticia|Enriquez-Navascues, Jose Maria|Boland, C Richard|Goel, Ajay|
PMID: 20924129
Journal: Pathologe. 2010 Oct;31(6):412-22.
Title: [Differential diagnostics of hereditary colorectal cancer syndromes. The role of pathology].
Author: Ruschoff, J|Heinmoller, E|Hartmann, A|Buttner, R|Rau, T
PMID: 20960194
Journal: Endoscopy. 2010 Dec;42(12):1071-6.
Title: Risk factors for advanced lesions undetected at prior colonoscopy: not always poor preparation.
Author: Ferrandez, A|Navarro, M|Diez, M|Sopena, F|Roncales, P|Polo-Tomas, M|Sainz, R|Lanas, A
PMID: 20960390
Journal: Jpn J Clin Oncol. 2010 Dec;40(12):1121-7.
Title: Hereditary non-polyposis colorectal cancer/Lynch syndrome in Korean patients with endometrial cancer.
Author: Lim, Myong Cheol|Seo, Sang-Soo|Kang, Sokbom|Seong, Moon-Woo|Lee, Bo-Yon|Park, Sang-Yoon
PMID: 20965939
Journal: PLoS One. 2010 Oct 13;5(10):e13314.
Title: Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Author: Mrkonjic, Miralem|Roslin, Nicole M|Greenwood, Celia M|Raptis, Stavroula|Pollett, Aaron|Laird, Peter W|Pethe, Vaijayanti V|Chiang, Theodore|Daftary, Darshana|Dicks, Elizabeth|Thibodeau, Stephen N|Gallinger, Steven|Parfrey, Patrick S|Younghusband, H Banfiel
PMID: 20967208
Journal: Cancer Prev Res (Phila). 2010 Nov;3(11):1409-16.
Title: An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy.
Author: Xie, Jenny|Guillemette, Shawna|Peng, Min|Gilbert, Candace|Buermeyer, Andrew|Cantor, Sharon B
PMID: 20978114
Journal: BMC Cancer. 2010 Oct 27;10:587.
Title: Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
Author: Pinheiro, Manuela|Ahlquist, Terje|Danielsen, Stine A|Lind, Guro E|Veiga, Isabel|Pinto, Carla|Costa, Vera|Afonso, Luis|Sousa, Olga|Fragoso, Maria|Santos, Lucio|Henrique, Rui|Lopes, Paula|Lopes, Carlos|Lothe, Ragnhild A|Teixeira, Manuel R
PMID: 20979647
Journal: BMB Rep. 2010 Oct;43(10):693-7.
Title: Three novel germline mutations in MLH1 and MSH2 in families with Lynch syndrome living on Jeju island, Korea.
Author: Kim, Young Mee|Choe, Chang Gyu|Cho, Somi Kim|Jung, In Ho|Chang, Won Young|Cho, Moonjae
PMID: 21034533
Journal: Am J Pathol. 2010 Dec;177(6):2731-40.
Title: Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author: Tanaka, Noriko|Huttenhower, Curtis|Nosho, Katsuhiko|Baba, Yoshifumi|Shima, Kaori|Quackenbush, John|Haigis, Kevin M|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21037082
Journal: Am J Surg Pathol. 2010 Dec;34(12):1798-804.
Title: Neoadjuvant therapy induces loss of MSH6 expression in colorectal carcinoma.
Author: Bao, Fei|Panarelli, Nicole C|Rennert, Hanna|Sherr, David L|Yantiss, Rhonda K
PMID: 21107085
Journal: Asia Pac J Clin Oncol. 2010 Dec;6(4):260-9.
Title: Microsatellite instability in colorectal cancer.
Author: Iacopetta, Barry|Grieu, Fabienne|Amanuel, Benhur
PMID: 21114775
Journal: Zhonghua Zhong Liu Za Zhi. 2010 Aug;32(8):590-4.
Title: [Expression and significance of mismatch repair genes hMLH1 and hMSH2 in sporadic colorectal carcinoma].
Author: Zheng, Jian-yun|Ren, Tian-shun|Liu, Bing|Wang, Mei-ni|Liao, He-he
PMID: 21122410
Journal: Cancer Genet Cytogenet. 2010 Dec;203(2):316-23.
Title: Screening for common copy-number variants in cancer genes.
Author: Tyson, Jess|Majerus, Tamsin M O|Walker, Susan|Armour, John A L
PMID: 21156252
Journal: World J Gastrointest Oncol. 2010 Mar 15;2(3):151-8.
Title: Differential colorectal carcinogenesis: Molecular basis and clinical relevance.
Author: Moran, Alberto|Ortega, Paloma|de Juan, Carmen|Fernandez-Marcelo, Tamara|Frias, Cristina|Sanchez-Pernaute, Andres|Torres, Antonio Jose|Diaz-Rubio, Eduardo|Iniesta, Pilar|Benito, Manuel
PMID: 21160823
Journal: BMC Genomics. 2010 Dec 20;11:717.
Title: Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction.
Author: Jaeger, Samira|Sers, Christine T|Leser, Ulf
PMID: 21171995
Journal: Chin Med Sci J. 2010 Dec;25(4):206-10.
Title: Expression of cyclooxygenase-2 and its relationship with mismatch repair and microsatellite instability in hereditary nonpolyposis colorectal cancer.
Author: Peng, Jin|Jian-qiu, Sheng|Ying-hui, Zhang|Ai-qin, Li|Zi-tao, Wu|Shi-rong, Li
PMID: 21232179
Journal: Isr Med Assoc J. 2010 Sep;12(9):549-53.
Title: A protocol for genetic evaluation of patients with multiple colorectal adenomas and without evidence of APC gene mutation.
Author: Rosner, Guy|Rozen, Paul|Bercovich, Dani|Shochat, Chen|Solar, Irit|Strul, Hana|Kariv, Revital|Halpern, Zamir
PMID: 21287799
Journal: Pol Merkur Lekarski. 2010 Dec;29(174):351-6.
Title: [Diagnostic and prognostic values of repair protein hMLH1, hMSH2 and protein CD34 immunoexpression in sporadic colorectal cancer].
Author: Slomka, Marta|Stasikowska, Olga|Wagrowska-Danilewicz, Malgorzata|Danilewicz, Marian|Malecka-Panas, Ewa
PMID: 21298983
Journal: Klin Onkol. 2010;23(6):388-400.
Title: Genetic testing and prevention of hereditary cancer at the MMCI--over 10 years of experience.
Author: Foretova, L|Petrakova, K|Palacova, M|Kalabova, R|Svoboda, M|Navratilova, M|Schneiderova, M|Bolcak, K|Krejci, E|Drazan, L|Mikova, M|Hazova, J|Vasickova, P|Machackova, E
PMID: 21348412
Journal: Yi Chuan. 2010 Dec;32(12):1241-6.
Title: [Association of mismatch repair gene polymorphism with susceptibility to sporadic colorectal cancer in Tianjin region].
Author: Li, Hui-Chen|Feng, Hui-Yuan|Zhang, Xi-Peng|Liu, Rui|Ma, Dong-Wang|Qin, Hai|Zhou, Yi|Yu, Lin
PMID: 21513149
Journal: Oncol Lett. 2010 Jan;1(1):23-29.
Title: Molecular prognostic factors in rectal cancer treated by preoperative chemoradiotherapy.
Author: Nam, Taek-Keun|Lee, Ji-Shin|Kim, Hyeong-Rok|Ahn, Sung-Ja|Song, Ju-Young|Yoon, Mee Sun
PMID: 22966250
Journal: Exp Ther Med. 2010 Mar;1(2):241-250.
Title: Dietary factors, genetic and epigenetic influences in colorectal cancer.
Author: Pellegrini, M L|Argibay, P|Gomez, D E
PMID: 22993535
Journal: Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author: Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20473920
Journal: Colorectal Dis. 2011 Sep;13(9):984-8.
Title: The relationship between serum vascular endothelial growth factor A and microsatellite instability in colorectal cancer.
Author: Hansen, T F|Jensen, L H|Spindler, K-L G|Lindebjerg, J|Brandslund, I|Jakobsen, A
PMID: 20594200
Journal: Fam Cancer. 2011 Mar;10(1):27-35.
Title: An intronic mutation in MLH1 associated with familial colon and breast cancer.
Author: Bianchi, F|Raponi, M|Piva, F|Viel, A|Bearzi, I|Galizia, E|Bracci, R|Belvederesi, L|Loretelli, C|Brugiati, C|Corradini, F|Baralle, D|Cellerino, R
PMID: 20717847
Journal: Gastroenterology. 2011 Jan;140(1):73-81.
Title: The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.
Author: Kastrinos, Fay|Steyerberg, Ewout W|Mercado, Rowena|Balmana, Judith|Holter, Spring|Gallinger, Steven|Siegmund, Kimberly D|Church, James M|Jenkins, Mark A|Lindor, Noralane M|Thibodeau, Stephen N|Burbidge, Lynn Anne|Wenstrup, Richard J|Syngal, Sapna
PMID: 20727894
Journal: Biosci Rep. 2011 Aug;31(4):257-64.
Title: Aberrant methylation of hMLH1 and p16INK4a in Tunisian patients with sporadic colorectal adenocarcinoma.
Author: Miladi-Abdennadher, Imen|Abdelmaksoud-Damak, Rania|Ayadi, Lobna|Khabir, Abdelmajid|Frikha, Foued|Kallel, Lamia|Frikha, Mounir|Sellami-Boudawara, Tahia|Gargouri, Ali|Mokdad-Gargouri, Raja
PMID: 20815811
Journal: Cancer. 2011 Feb 1;117(3):492-500.
Title: Evidence for an hMSH3 defect in familial hamartomatous polyps.
Author: Huang, Sherry C|Lee, Jeffrey K|Smith, E Julieta|Doctolero, Ryan T|Tajima, Akihiro|Beck, Stayce E|Weidner, Noel|Carethers, John M
PMID: 20845481
Journal: Ann Surg Oncol. 2011 Mar;18(3):711-9.
Title: Loss of E-cadherin and MUC2 expressions correlated with poor survival in patients with stages II and III colorectal carcinoma.
Author: Kang, Haeyoun|Min, Byung Soh|Lee, Kang Young|Kim, Nam Kyu|Kim, Soo Nyung|Choi, Junjeong|Kim, Hoguen
PMID: 20865330
Journal: Nucleic Acids Res. 2011 Jan;39(1):e5.
Title: MethylViewer: computational analysis and editing for bisulfite sequencing and methyltransferase accessibility protocol for individual templates (MAPit) projects.
Author: Pardo, Carolina E|Carr, Ian M|Hoffman, Christopher J|Darst, Russell P|Markham, Alexander F|Bonthron, David T|Kladde, Michael P
PMID: 20959287
Journal: Clin Gastroenterol Hepatol. 2011 Jun;9(6):497-502.
Title: Prevalence of alterations in DNA mismatch repair genes in patients with young-onset colorectal cancer.
Author: Limburg, Paul J|Harmsen, William S|Chen, Helen H|Gallinger, Steven|Haile, Robert W|Baron, John A|Casey, Graham|Woods, Michael O|Thibodeau, Stephen N|Lindor, Noralane M
PMID: 21056691
Journal: Gut. 2011 Apr;60(4):499-508.
Title: Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression.
Author: Ibrahim, Ashraf E K|Arends, Mark J|Silva, Ana-Luisa|Wyllie, Andrew H|Greger, Liliana|Ito, Yoko|Vowler, Sarah L|Huang, Tim H-M|Tavare, Simon|Murrell, Adele|Brenton, James D
PMID: 21068132
Journal: Clin Gastroenterol Hepatol. 2011 Apr;9(4):340-3.
Title: Rapid development of colorectal neoplasia in patients with Lynch syndrome.
Author: Edelstein, Daniel L|Axilbund, Jennifer|Baxter, Melanie|Hylind, Linda M|Romans, Katharine|Griffin, Constance A|Cruz-Correa, Marcia|Giardiello, Francis M
PMID: 21070872
Journal: J Med Genet. 2011 Apr;48(4):279-84.
Title: Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.
Author: Talseth-Palmer, Bente A|Brenne, Ingvild S|Ashton, Katie A|Evans, Tiffany-Jane|McPhillips, Mary|Groombridge, Claire|Suchy, Janina|Kurzawski, Grzegorz|Spigelman, Allan|Lubinski, Jan|Scott, Rodney J
PMID: 21097774
Journal: Mod Pathol. 2011 Mar;24(3):396-411.
Title: Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.
Author: Wong, Justin J-L|Hawkins, Nicholas J|Ward, Robyn L|Hitchins, Megan P
PMID: 21102416
Journal: Oncol Rep. 2011 Jan;25(1):167-72.
Title: Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients.
Author: Kim, Jong Woo|Park, Hye Mi|Choi, Young-Kook|Chong, So Young|Oh, Doyeun|Kim, Nam Keun
PMID: 21109973
Journal: Int J Cancer. 2011 Oct 1;129(7):1643-50.
Title: Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.
Author: Duraturo, Francesca|Liccardo, Raffaella|Cavallo, Angela|De Rosa, Marina|Grosso, Michela|Izzo, Paola
PMID: 21128252
Journal: Fam Cancer. 2011 Jun;10(2):255-63.
Title: Non-truncating hMLH1 variants identified in Slovenian gastric cancer patients are not associated with Lynch Syndrome: a functional analysis report.
Author: Vogelsang, Matjaz|Komel, Radovan
PMID: 21136174
Journal: Cancer Causes Control. 2011 Feb;22(2):301-9.
Title: MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author: Shima, Kaori|Morikawa, Teppei|Baba, Yoshifumi|Nosho, Katsuhiko|Suzuki, Maiko|Yamauchi, Mai|Hayashi, Marika|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21140203
Journal: Lancet Oncol. 2011 Jan;12(1):49-55.
Title: Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study.
Author: Kempers, Marlies J E|Kuiper, Roland P|Ockeloen, Charlotte W|Chappuis, Pierre O|Hutter, Pierre|Rahner, Nils|Schackert, Hans K|Steinke, Verena|Holinski-Feder, Elke|Morak, Monika|Kloor, Matthias|Buttner, Reinhard|Verwiel, Eugene T P|van Krieken, J Han|Nagteg
PMID: 21145788
Journal: Eur J Hum Genet. 2011 Mar;19(3):320-5.
Title: Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer.
Author: Yoshida, Rintaro|Miyashita, Kaname|Inoue, Mayuko|Shimamoto, Akiyoshi|Yan, Zhao|Egashira, Akinori|Oki, Eiji|Kakeji, Yoshishiro|Oda, Shinya|Maehara, Yoshihiko
PMID: 21157497
Journal: J Clin Pathol. 2011 Feb;64(2):141-5.
Title: MLH1 function is context dependent in colorectal cancers.
Author: Jackson, Thomas|Ahmed, Mohamed A H|Seth, Rashmi|Jackson, Darryl|Ilyas, Mohammad
PMID: 21169277
Journal: Oncol Rep. 2011 Mar;25(3):789-94.
Title: Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author: Aoyagi, Haruhiko|Iida, Satoru|Uetake, Hiroyuki|Ishikawa, Toshiaki|Takagi, Yoko|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Yasuno, Masamichi|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 21174064
Journal: Gastroenterology. 2011 Apr;140(4):1174-81.
Title: 5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer.
Author: Jover, Rodrigo|Nguyen, Thuy-Phuong|Perez-Carbonell, Lucia|Zapater, Pedro|Paya, Artemio|Alenda, Cristina|Rojas, Estefania|Cubiella, Joaquin|Balaguer, Francesc|Morillas, Juan D|Clofent, Juan|Bujanda, Luis|Rene, Josep M|Bessa, Xavier|Xicola, Rosa M|Nicolas-P
PMID: 21185836
Journal: Gut. 2011 Jul;60(7):950-7.
Title: Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.
Author: Parry, Susan|Win, Aung Ko|Parry, Bryan|Macrae, Finlay A|Gurrin, Lyle C|Church, James M|Baron, John A|Giles, Graham G|Leggett, Barbara A|Winship, Ingrid|Lipton, Lara|Young, Graeme P|Young, Joanne P|Lodge, Caroline J|Southey, Melissa C|Newcomb, Polly A|Le M
PMID: 21193451
Journal: Oncol Rep. 2011 Mar;25(3):809-15.
Title: Functional effects of the MLH1-93G>A polymorphism on MLH1/EPM2AIP1 promoter activity.
Author: Perera, Sheron|Mrkonjic, Miralem|Rawson, James B|Bapat, Bharati
PMID: 21206982
Journal: J Mol Diagn. 2011 Jan;13(1):93-9.
Title: Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases.
Author: Rumilla, Kandelaria|Schowalter, Karen V|Lindor, Noralane M|Thomas, Brittany C|Mensink, Kara A|Gallinger, Steven|Holter, Spring|Newcomb, Polly A|Potter, John D|Jenkins, Mark A|Hopper, John L|Long, Tiffany I|Weisenberger, Daniel J|Haile, Robert W|Casey, Gra
PMID: 21227399
Journal: Genet Med. 2011 Feb;13(2):155-60.
Title: Novel MLH1 duplication identified in Colombian families with Lynch syndrome.
Author: Alonso-Espinaco, Virginia|Giraldez, Maria Dolores|Trujillo, Carlos|van der Klift, Heleen|Munoz, Jenifer|Balaguer, Francesc|Ocana, Teresa|Madrigal, Irene|Jones, Angela M|Echeverry, M Magdalena|Velez, Alejandro|Tomlinson, Ian|Mila, Montserrat|Wijnen, Juul|C
PMID: 21233718
Journal: BMC Med Genet. 2011 Jan 19;12:12.
Title: Evidence for classification of c.1852_1853AA>GC in MLH1 as a neutral variant for Lynch syndrome.
Author: Castillejo, Adela|Guarinos, Carla|Martinez-Canto, Ana|Barbera, Victor-Manuel|Egoavil, Cecilia|Castillejo, Maria-Isabel|Perez-Carbonell, Lucia|Sanchez-Heras, Ana-Beatriz|Segura, Angel|Ochoa, Enrique|Lazaro, Rafael|Ruiz-Ponte, Clara|Bujanda, Luis|Andreu, Mo
PMID: 21247423
Journal: J Biol Chem. 2011 Apr 8;286(14):12157-65.
Title: MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor.
Author: Takahashi, Masanobu|Koi, Minoru|Balaguer, Francesc|Boland, C Richard|Goel, Ajay
PMID: 21285347
Journal: Oncol Rep. 2011 Apr;25(4):899-904.
Title: Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma.
Author: Colombino, Maria|Avallone, Antonio|Izzo, Francesco|Tatangelo, Fabiana|Budroni, Mario|Cossu, Antonio|Galimi, Francesco|Comella, Pasquale|Botti, Gerardo|Sini, Maria Cristina|Tanda, Francesco|Palmieri, Giuseppe
PMID: 21286667
Journal: Fam Cancer. 2011 Jun;10(2):285-95.
Title: Identification and surveillance of 19 Lynch syndrome families in southern Italy: report of six novel germline mutations and a common founder mutation.
Author: Lastella, Patrizia|Patruno, Margherita|Forte, Giovanna|Montanaro, Alba|Di Gregorio, Carmela|Sabba, Carlo|Suppressa, Patrizia|Piepoli, Adalgisa|Panza, Anna|Andriulli, Angelo|Resta, Nicoletta|Stella, Alessandro
PMID: 21286823
Journal: Clin Neurol Neurosurg. 2011 Jun;113(5):411-5.
Title: Glioblastoma multiforme in the Muir-Torre syndrome.
Author: Binder, Zev A|Johnson, Michael W|Joshi, Avadhut|Hann, Christine L|Griffin, Constance A|Olivi, Alessandro|Riggins, Gregory J|Gallia, Gary L
PMID: 21288634
Journal: Carcinogenesis. 2011 Apr;32(4):636-42.
Title: LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability.
Author: Melcher, Ralph|Hartmann, Elena|Zopf, Waltraud|Herterich, Sabine|Wilke, Philipp|Muller, Ludwig|Rosler, Eduard|Kudlich, Theodor|Al-Taie, Oliver|Rosenwald, Andreas|Katzenberger, Tiemo|Scholtka, Bettina|Seibold, Stefan|Rogoll, Dorothee|Scheppach, Wolfgang|Sch
PMID: 21297112
Journal: Am J Surg Pathol. 2011 Mar;35(3):447-54.
Title: Immunohistochemical staining for DNA mismatch repair proteins in intestinal tract carcinoma: how reliable are biopsy samples?
Author: Shia, Jinru|Stadler, Zsofia|Weiser, Martin R|Rentz, Michael|Gonen, Mithat|Tang, Laura H|Vakiani, Efsevia|Katabi, Nora|Xiong, Xiaoling|Markowitz, Arnold J|Shike, Moshe|Guillem, Jose|Klimstra, David S
PMID: 21297438
Journal: Int J Colorectal Dis. 2011 Apr;26(4):455-67.
Title: Lynch syndrome in Tunisia: first description of clinical features and germline mutations.
Author: Moussa, Sana Aissi-Ben|Moussa, Amel|Kourda, Nadia|Mezlini, Amel|Abdelli, Nabil|Zerimech, Farid|Najjar, Taoufik|Jilani, Sarah Ben|Porchet, Nicole|Ayed, Farhat Ben|Manai, Mohamed|Buisine, Marie-Pierre
PMID: 21311894
Journal: Hum Pathol. 2011 Jul;42(7):1047-52.
Title: A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author: Pancione, Massimo|Di Blasi, Arturo|Sabatino, Lina|Fucci, Alessandra|Dalena, Anna Maria|Palombi, Natalia|Carotenuto, Pietro|Aquino, Gabriella|Daniele, Bruno|Normanno, Nicola|Colantuoni, Vittorio
PMID: 21315413
Journal: Mod Pathol. 2011 May;24(5):729-38.
Title: Clinicopathological and molecular characterization of colorectal micropapillary carcinoma.
Author: Verdu, Montse|Roman, Ruth|Calvo, Miquel|Rodon, Natalia|Garcia, Beatriz|Gonzalez, Marta|Vidal, August|Puig, Xavier
PMID: 21336262
Journal: Ann Surg Oncol. 2011 Dec;18(13):3694-700.
Title: Molecular profiling of colon tumors: the search for clinically relevant biomarkers of progression, prognosis, therapeutics, and predisposition.
Author: Bacolod, Manny D|Barany, Francis
PMID: 21347779
Journal: Kaohsiung J Med Sci. 2011 Feb;27(2):68-71.
Title: A novel nonsense mutation of MSH2 gene in a Taiwanese family with hereditary nonpolyposis colorectal cancer.
Author: Chen, Wen-Chau|Lin, Shao-Chieh|Lee, Jenq-Chang
PMID: 21354521
Journal: Clin Cancer Res. 2011 Apr 1;17(7):1701-12.
Title: Analysis of the oxidative damage repair genes NUDT1, OGG1, and MUTYH in patients from mismatch repair proficient HNPCC families (MSS-HNPCC).
Author: Garre, Pilar|Briceno, Veronica|Xicola, Rosa M|Doyle, Brian J|de la Hoya, Miguel|Sanz, Julian|Llovet, Patricia|Pescador, Paula|Puente, Javier|Diaz-Rubio, Eduardo|Llor, Xavier|Caldes, Trinidad
PMID: 21355073
Journal: Clin Genet. 2011 Nov;80(5):428-34.
Title: Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort.
Author: Hitchins, M P|Owens, S E|Kwok, C-T|Godsmark, G|Algar, U F|Ramesar, R S
PMID: 21375527
Journal: Oncol Rep. 2011 May;25(5):1195-201.
Title: Preclinical in vitro models from genetically engineered mice for breast and colon cancer (Review).
Author: Telang, Nitin|Katdare, Meena
PMID: 21399881
Journal: Int J Cancer. 2011 Dec 15;129(12):2855-66.
Title: Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas.
Author: Oster, Bodil|Thorsen, Kasper|Lamy, Philippe|Wojdacz, Tomasz K|Hansen, Lise Lotte|Birkenkamp-Demtroder, Karin|Sorensen, Karina D|Laurberg, Soren|Orntoft, Torben F|Andersen, Claus L
PMID: 21400501
Journal: Eur J Hum Genet. 2011 Aug;19(8):887-92.
Title: Evaluation of Lynch syndrome modifier genes in 748 MMR mutation carriers.
Author: Houlle, Solene|Charbonnier, Francoise|Houivet, Estelle|Tinat, Julie|Buisine, Marie-Pierre|Caron, Olivier|Benichou, Jacques|Baert-Desurmont, Stephanie|Frebourg, Thierry
PMID: 21407259
Journal: Future Oncol. 2011 Mar;7(3):467-74.
Title: Prognostic and predictive impact of DNA mismatch repair in the management of colorectal cancer.
Author: Sinicrope, Frank A|Yang, Zhineng Jayson
PMID: 21417908
Journal: Am J Surg Pathol. 2011 May;35(5):647-55.
Title: Clinicopathologic and molecular profiles of microsatellite unstable Barrett Esophagus-associated adenocarcinoma.
Author: Farris, Alton B 3rd|Demicco, Elizabeth G|Le, Long Phe|Finberg, Karin E|Miller, Julie|Mandal, Rajni|Fukuoka, Junya|Cohen, Cynthia|Gaissert, Henning A|Zukerberg, Lawrence R|Lauwers, Gregory Y|Iafrate, A John|Mino-Kenudson, Mari
PMID: 21422910
Journal: Fam Cancer. 2011 Sep;10(3):515-20.
Title: A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one.
Author: Kantelinen, Jukka|Hansen, Thomas V O|Kansikas, Minttu|Krogh, Lotte Nylandsted|Korhonen, Mari K|Ollila, Saara|Nystrom, Minna|Gerdes, Anne-Marie|Kariola, Reetta
PMID: 21431882
Journal: Pathology. 2011 Apr;43(3):228-33.
Title: Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations.
Author: Egoavil, C M|Montenegro, P|Soto, J L|Casanova, L|Sanchez-Lihon, J|Castillejo, M I|Martinez-Canto, A|Perez-Carbonell, L|Castillejo, A|Guarinos, C|Barbera, V M|Jover, R|Paya, A|Alenda, C
PMID: 21436632
Journal: Bull Cancer. 2011 Mar;98(3):323-36.
Title: [HNPCC (hereditary non-polyposis colorectal cancer) or Lynch syndrome: a syndrome related to a failure of DNA repair system].
Author: Manceau, Gilles|Karoui, Mehdi|Charachon, Antoine|Delchier, Jean-Charles|Sobhani, Iradj
PMID: 21459714
Journal: Ann Biol Clin (Paris). 2011 Mar-Apr;69(2):167-73.
Title: [Utility of immunohistochemistry in detecting alterations of mismatch repair genes of DNA. A series of 48 cases of colorectal cancer].
Author: Ziadi, Sonia|Gacem, Riath Ben|Haoues, Imen|Hachana, Mouhamed|Amara, Khaled|Trimeche, Mounir|Golli, Lamia|Mokni, Moncef|Korbi, Sadok
PMID: 21464009
Journal: Dis Colon Rectum. 2011 May;54(5):515-7.
Title: How helpful is age at colorectal cancer onset in finding HNPCC?
Author: Lynch, Patrick M
PMID: 21471750
Journal: Cell Oncol (Dordr). 2011 Jun;34(3):155-76.
Title: Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications.
Author: Zaanan, Aziz|Meunier, Katy|Sangar, Fatiha|Flejou, Jean-Francois|Praz, Francoise
PMID: 21484480
Journal: Mod Pathol. 2011 Jul;24(7):1004-14.
Title: A two-antibody mismatch repair protein immunohistochemistry screening approach for colorectal carcinomas, skin sebaceous tumors, and gynecologic tract carcinomas.
Author: Mojtahed, Amirkaveh|Schrijver, Iris|Ford, James M|Longacre, Teri A|Pai, Reetesh K
PMID: 21499234
Journal: J Med Life. 2011 Jan-Mar;4(1):109-11. Epub 2011 Feb 25.
Title: Map syndrome (MYH Associated Polyposis) colorectal cancer, etiopathological connections.
Author: Bolocan, A|Ion, D|Stoian, R V|Serban, M B
PMID: 21505584
Journal: Cancer. 2011 May 1;117(9):1847-54.
Title: DNA methylation predicts recurrence from resected stage III proximal colon cancer.
Author: Ahn, Joong Bae|Chung, Woon Bok|Maeda, Osamu|Shin, Sang Joon|Kim, Hyun Soo|Chung, Hyun Chul|Kim, Nam Kyu|Issa, Jean-Pierre J
PMID: 21509761
Journal: Hum Mutat. 2011 May;32(5):551-6.
Title: Biomedical informatics as support to individual healthcare in hereditary colon cancer: the Danish HNPCC system.
Author: Bernstein, Inge T|Lindorff-Larsen, Karen|Timshel, Susanne|Brandt, Carsten A|Dinesen, Birger|Fenger, Mogens|Gerdes, Anne-Marie|Iversen, Lene H|Madsen, Mogens R|Okkels, Henrik|Sunde, Lone|Rahr, Hans B|Wikman, Friedrick P|Rossing, Niels
PMID: 21520332
Journal: Br J Cancer. 2011 Jun 28;105(1):162-9.
Title: Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes.
Author: Win, A K|Dowty, J G|English, D R|Campbell, P T|Young, J P|Winship, I|Macrae, F A|Lipton, L|Parry, S|Young, G P|Buchanan, D D|Martinez, M E|Jacobs, E T|Ahnen, D J|Haile, R W|Casey, G|Baron, J A|Lindor, N M|Thibodeau, S N|Newcomb, P A|Potter, J D|Le Marchan
PMID: 21559014
Journal: Carcinogenesis. 2011 Aug;32(8):1157-61.
Title: MLH1-93G > A is a risk factor for MSI colorectal cancer.
Author: Whiffin, Nicola|Broderick, Peter|Lubbe, Steven J|Pittman, Alan M|Penegar, Steven|Chandler, Ian|Houlston, Richard S
PMID: 21565826
Journal: Mutat Res. 2011 Jul 1;712(1-2):40-8.
Title: Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1.
Author: Vernole, Patrizia|Muzi, Alessia|Volpi, Antonio|Terrinoni, Alessandro|Dorio, Annalisa Susanna|Tentori, Lucio|Shah, Girish M|Graziani, Grazia
PMID: 21570414
Journal: Mod Pathol. 2011 Sep;24(9):1221-8.
Title: Folate receptor-alpha expression in resectable hepatic colorectal cancer metastases: patterns and significance.
Author: D'Angelica, Michael|Ammori, John|Gonen, Mithat|Klimstra, David S|Low, Philip S|Murphy, Linda|Weiser, Martin R|Paty, Philip B|Fong, Yuman|Dematteo, Ronald P|Allen, Peter|Jarnagin, William R|Shia, Jinru
PMID: 21572402
Journal: Med Clin (Barc). 2011 Jul 9;137(4):166-70.
Title: [Patients with clinical criteria for Lynch syndrome with and without mutations in DNA repair genes (MLH1 and MSH2). A challenge for the clinician].
Author: Seijas Tamayo, Raquel|Martin Gomez, Teresa|Perez Garcia, Jessica|Macias Alvarez, Laura|Sanchez Barba, Mercedes|Castro Marcos, Elena|Sanchez Tapia, Eva Maria|Gonzalez Sarmiento, Rogelio|Cruz Hernandez, Juan Jesus
PMID: 21601892
Journal: J Gastroenterol Hepatol. 2011 Dec;26(12):1733-9.
Title: Mismatch repair status in sporadic colorectal cancer: immunohistochemistry and microsatellite instability analyses.
Author: Yoon, Yong Sik|Yu, Chang Sik|Kim, Tae Won|Kim, Jong Hoon|Jang, Se Jin|Cho, Dong Hyung|Roh, Seon Ae|Kim, Jin Cheon
PMID: 21615788
Journal: BMB Rep. 2011 May;44(5):317-22.
Title: Distinct mutations in MLH1 and MSH2 genes in hereditary non-polyposis colorectal cancer (HNPCC) families from China.
Author: Wei, Wenqian|Liu, Fangqi|Liu, Lei|Li, Zuofeng|Zhang, Xiaoyan|Jiang, Fan|Shi, Qu|Zhou, Xiaoyan|Sheng, Weiqi|Cai, Sanjun|Li, Xuan|Xu, Ye|Nan, Peng
PMID: 21615986
Journal: Inflamm Bowel Dis. 2011 Sep;17(9):1966-70.
Title: Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer.
Author: Sanchez, Julian A|Dejulius, Kathryn L|Bronner, Mary|Church, James M|Kalady, Matthew F
PMID: 21618350
Journal: Tumour Biol. 2011 Aug;32(4):653-9.
Title: Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.
Author: Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Kielan, Wojciech|Sasiadek, Maria Malgorzata
PMID: 21625944
Journal: J Med Genet. 2011 Aug;48(8):530-4.
Title: Determining the frequency of de novo germline mutations in DNA mismatch repair genes.
Author: Win, Aung Ko|Jenkins, Mark A|Buchanan, Daniel D|Clendenning, Mark|Young, Joanne P|Giles, Graham G|Goldblatt, Jack|Leggett, Barbara A|Hopper, John L|Thibodeau, Stephen N|Lindor, Noralane M
PMID: 21636617
Journal: Am J Pathol. 2011 Jun;178(6):2700-7.
Title: A serrated colorectal cancer pathway predominates over the classic WNT pathway in patients with hyperplastic polyposis syndrome.
Author: Boparai, Karam S|Dekker, Evelien|Polak, Mirjam M|Musler, Alex R|van Eeden, Susanne|van Noesel, Carel J M
PMID: 21641392
Journal: JAMA. 2011 Jun 8;305(22):2304-10.
Title: Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.
Author: Bonadona, Valerie|Bonaiti, Bernard|Olschwang, Sylviane|Grandjouan, Sophie|Huiart, Laetitia|Longy, Michel|Guimbaud, Rosine|Buecher, Bruno|Bignon, Yves-Jean|Caron, Olivier|Colas, Chrystelle|Nogues, Catherine|Lejeune-Dumoulin, Sophie|Olivier-Faivre, Laurence
PMID: 21642682
Journal: World J Surg Oncol. 2011 Jun 6;9:62.
Title: Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case.
Author: Schiergens, Tobias S|Khalil, Philipe N|Mayr, Doris|Thasler, Wolfgang E|Angele, Martin K|Hatz, Rudolf A|Jauch, Karl-Walter|Kleespies, Axel
PMID: 21645337
Journal: J Biomed Sci. 2011 Jun 7;18:36.
Title: Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan.
Author: Lin, Chien-Hsing|Lin, Jen-Kou|Chang, Shih-Ching|Chang, Ya-Hui|Chang, Hwey-May|Liu, Jin-Hwang|Li, Ling-Hui|Chen, Yuan-Tsong|Tsai, Shih-Feng|Chen, Wei-Shone
PMID: 21645411
Journal: Expert Rev Gastroenterol Hepatol. 2011 Jun;5(3):385-99.
Title: Microsatellite instability in the management of colorectal cancer.
Author: Pino, Maria S|Chung, Daniel C
PMID: 21651356
Journal: Hum Pathol. 2011 Dec;42(12):1897-910.
Title: Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Author: Nyiraneza, Christine|Jouret-Mourin, Anne|Kartheuser, Alex|Camby, Philippe|Plomteux, Olivier|Detry, Roger|Dahan, Karin|Sempoux, Christine
PMID: 21665242
Journal: PLoS One. 2011;6(6):e20465.
Title: miRNA expression in colon polyps provides evidence for a multihit model of colon cancer.
Author: Oberg, Ann L|French, Amy J|Sarver, Aaron L|Subramanian, Subbaya|Morlan, Bruce W|Riska, Shaun M|Borralho, Pedro M|Cunningham, Julie M|Boardman, Lisa A|Wang, Liang|Smyrk, Thomas C|Asmann, Yan|Steer, Clifford J|Thibodeau, Stephen N
PMID: 21694772
Journal: Fam Cancer. 2011 Dec;10(4):649-54.
Title: Factors affecting encouragement of relatives among families with Lynch syndrome to seek medical assessment.
Author: Ishii, Noriko|Arai, Masami|Koyama, Yurie|Ueno, Masashi|Yamaguchi, Toshiharu|Kazuma, Keiko|Muto, Tetsuichiro
PMID: 21695501
Journal: Langenbecks Arch Surg. 2011 Oct;396(7):1017-26.
Title: Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence.
Author: Lee, Kyung-Hwa|Lee, Ji-Shin|Nam, Jong-Hee|Choi, Chan|Lee, Min-Cheol|Park, Chang-Soo|Juhng, Sang-Woo|Lee, Jae-Hyuk
PMID: 21706233
Journal: J Med Genet. 2011 Aug;48(8):513-9.
Title: Biallelic MLH1 SNP cDNA expression or constitutional promoter methylation can hide genomic rearrangements causing Lynch syndrome.
Author: Morak, Monika|Koehler, Udo|Schackert, Hans Konrad|Steinke, Verena|Royer-Pokora, Brigitte|Schulmann, Karsten|Kloor, Matthias|Hochter, Wilhelm|Weingart, Josef|Keiling, Cortina|Massdorf, Trisari|Holinski-Feder, Elke
PMID: 21712435
Journal: J Cancer. 2011;2:302-6. Epub 2011 May 23.
Title: Primary mucinous adenocarcinoma of the vermiform appendix with high grade microsatellite instability.
Author: Komm, Moritz|Kronawitter-Fesl, Michaela|Kremer, Marcus|Lutz, Ludwig|Holinski-Feder, Elke|Kopp, Reinhard
PMID: 21716905
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011 Jul;27(7):754-6.
Title: [Effect of estrogen on mismatch repair gene expression in colon cancer cells].
Author: Lu, Xiao-juan|Yu, Dong-liang|Wang, Jia-xin|Pan, Xiao-lu|Jin, Peng|Li, Shi-rong|Sheng, Jian-qiu
PMID: 21722527
Journal: Tumour Biol. 2011 Oct;32(5):977-83.
Title: Gene expression of the mismatch repair gene MSH2 in primary colorectal cancer.
Author: Jensen, Lars Henrik|Kuramochi, Hidekazu|Cruger, Dorthe Gylling|Lindebjerg, Jan|Kolvraa, Steen|Danenberg, Peter|Danenberg, Kathleen|Jakobsen, Anders
PMID: 21732224
Journal: PLoS One. 2011;6(6):e21102.
Title: B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author: Schernhammer, Eva S|Giovannucci, Edward|Baba, Yoshifumi|Fuchs, Charles S|Ogino, Shuji
PMID: 21738611
Journal: J BUON. 2011 Apr-Jun;16(2):265-73.
Title: Microsatellite instability and promoter hypermethylation of MLH1 and MSH2 in patients with sporadic colorectal cancer.
Author: Vlaykova, T|Mitkova, A|Stancheva, G|Kadiyska, T|Gulubova, M|Yovchev, Y|Cirovski, G|Chilingirov, P|Damyanov, D|Kremensky, I|Mitev, V|Kaneva, R
PMID: 21766496
Journal: Am J Gastroenterol. 2011 Oct;106(10):1829-36.
Title: Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion.
Author: Lynch, Henry T|Riegert-Johnson, Douglas L|Snyder, Carrie|Lynch, Jane F|Hagenkord, Jill|Boland, C Richard|Rhees, Jennifer|Thibodeau, Stephen N|Boardman, Lisa A|Davies, Janine|Kuiper, Roland P|Hoogerbrugge, Nicoline|Ligtenberg, Marjolijn J L
PMID: 21769135
Journal: J Clin Oncol. 2011 Sep 1;29(25):3374-80.
Title: Validation microsatellite path score in a population-based cohort of patients with colorectal cancer.
Author: Bessa, Xavier|Alenda, Cristina|Paya, Artemio|Alvarez, Cristina|Iglesias, Mar|Seoane, Agustin|Dedeu, Josep Maria|Abuli, Anna|Ilzarbe, Lucas|Navarro, Gemma|Pellise, Maria|Balaguer, Francesc|Castellvi-Bel, Sergi|Llor, Xavier|Castells, Antoni|Jover, Rodrigo|A
PMID: 21788563
Journal: Cancer Biol Ther. 2011 Oct 15;12(8):756-64.
Title: DNA mismatch repair proficiency executing 5-fluorouracil cytotoxicity in colorectal cancer cells.
Author: Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Carethers, John M
PMID: 21814034
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G929-37.
Title: Honokiol radiosensitizes colorectal cancer cells: enhanced activity in cells with mismatch repair defects.
Author: He, Zhiyun|Subramaniam, Dharmalingam|Ramalingam, Satish|Dhar, Animesh|Postier, Russell G|Umar, Shahid|Zhang, Youcheng|Anant, Shrikant
PMID: 21836060
Journal: Am J Surg Pathol. 2011 Sep;35(9):1391-9.
Title: Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function.
Author: Klarskov, Louise|Holck, Susanne|Bernstein, Inge|Okkels, Henrik|Rambech, Eva|Baldetorp, Bo|Nilbert, Mef
PMID: 21836479
Journal: Clin Cancer Res. 2011 Oct 1;17(19):6239-49.
Title: Colorectal cancers with microsatellite instability display unique miRNA profiles.
Author: Balaguer, Francesc|Moreira, Leticia|Lozano, Juan Jose|Link, Alexander|Ramirez, Georgina|Shen, Yan|Cuatrecasas, Miriam|Arnold, Mildred|Meltzer, Stephen J|Syngal, Sapna|Stoffel, Elena|Jover, Rodrigo|Llor, Xavier|Castells, Antoni|Boland, C Richard|Gironella,
PMID: 21844009
Journal: Nutr Cancer. 2011;63(7):1000-10.
Title: MLH1 promoter methylation, diet, and lifestyle factors in mismatch repair deficient colorectal cancer patients from EPIC-Norfolk.
Author: Gay, Laura J|Arends, Mark J|Mitrou, Panagiota N|Bowman, Richard|Ibrahim, Ashraf E|Happerfield, Lisa|Luben, Robert|McTaggart, Alison|Ball, Richard Y|Rodwell, Sheila A
PMID: 21875327
Journal: PLoS One. 2011;6(8):e24114.
Title: Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.
Author: Vasovcak, Peter|Pavlikova, Kristyna|Sedlacek, Zdenek|Skapa, Petr|Kouda, Martin|Hoch, Jiri|Krepelova, Anna
PMID: 21901162
Journal: Indian J Med Res. 2011 Aug;134:186-92.
Title: Mismatch repair genes expression defects & association with clinicopathological characteristics in colorectal carcinoma.
Author: Kaur, Gurjeet|Masoud, Abdelhafid|Raihan, N|Radzi, M|Khamizar, W|Kam, Lee Suk
PMID: 21911971
Journal: Urologe A. 2011 Dec;50(12):1614-6.
Title: [Bladder cancer at an early age in father and son].
Author: Ovsiannikov, D|Stohr, R|Hartmann, A|Bottrich, R|Hengstler, J G|Golka, K
PMID: 21938565
Journal: Arch Med Res. 2011 Aug;42(6):457-62.
Title: Analysis of DNA mismatch repair proteins expression and BRAF V600E mutation in a subset of early- and late-onset colorectal carcinoma patients in Mexico.
Author: Luevano-Gonzalez, Arturo|Guzman, Arturo Quintanilla|Ancer Rodriguez, Jesus|Ortiz Lopez, Rocio|Rojas Martinez, Augusto|Gonzalez Guerrero, Juan Francisco|Flores Gutierrez, Juan Pablo
PMID: 21945875
Journal: Adv Surg. 2011;45:265-74.
Title: Surgical management of hereditary nonpolyposis colorectal cancer.
Author: Kalady, Matthew F
PMID: 21954693
Journal: Arch Pathol Lab Med. 2011 Oct;135(10):1269-77.
Title: Microsatellite instability and colorectal cancer.
Author: Geiersbach, Katherine B|Samowitz, Wade S
PMID: 21970482
Journal: PLoS One. 2011;6(10):e25913.
Title: Spreading of Alu methylation to the promoter of the MLH1 gene in gastrointestinal cancer.
Author: Wang, Xiyin|Fan, Jing|Liu, Dong|Fu, Siqing|Ingvarsson, Sigurdur|Chen, Huiping
PMID: 22022465
Journal: Dis Colon Rectum. 2011 Dec;54(12):1480-7.
Title: Preoperative diagnosis of Lynch syndrome with DNA mismatch repair immunohistochemistry on a diagnostic biopsy.
Author: Warrier, S K|Trainer, A H|Lynch, A C|Mitchell, C|Hiscock, R|Sawyer, S|Boussioutas, A|Heriot, A G
PMID: 22067175
Journal: Am J Surg Pathol. 2011 Dec;35(12):1902-5.
Title: Null pattern of immunoreactivity in a Lynch syndrome-associated colon cancer due to germline MSH2 mutation and somatic MLH1 hypermethylation.
Author: Hagen, Catherine E|Lefferts, Joel|Hornick, Jason L|Srivastava, Amitabh
PMID: 22067334
Journal: Hinyokika Kiyo. 2011 Oct;57(10):559-63.
Title: [Metachronous urothelial cancer in bilateral upper urinary tracts and bladder associated with hereditary nonpolyposis colorectal cancer].
Author: Yamada, Yusuke|Ueda, Yasuo|Higuchi, Yoshihide|Suzuki, Toru|Maruyama, Takuo|Kondoh, Yoshinobu|Nojima, Michio|Noda, Masashi|Tomita, Naohiro|Zozumi, Masataka|Hirota, Seiichi|Yamamoto, Shingo
PMID: 22089154
Journal: Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):562-8.
Title: Expression of p16INK4a, alone or combined with p53, is predictive of better prognosis in colorectal adenocarcinoma in Tunisian patients.
Author: Miladi-Abdennadher, Imen|Abdelmaksoud-Damak, Rania|Ayadi, Lobna|Khabir, Abdelmajid|Amouri, Ali|Frikha, Foued|Ellouz, Sameh|Frikha, Mounir|Sellami-Boudawara, Tahia|Mokdad-Gargouri, Raja
PMID: 22095233
Journal: PLoS One. 2011;6(11):e27889.
Title: DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.
Author: Konishi, Kazuo|Watanabe, Yoshiyuki|Shen, Lanlan|Guo, Yi|Castoro, Ryan J|Kondo, Kimie|Chung, Woonbok|Ahmed, Saira|Jelinek, Jaroslav|Boumber, Yanis A|Estecio, Marcos R|Maegawa, Shinji|Kondo, Yutaka|Itoh, Fumio|Imawari, Michio|Hamilton, Stanley R|Issa, Jean-
PMID: 22132162
Journal: Nihon Shokakibyo Gakkai Zasshi. 2011 Dec;108(12):2016-22.
Title: [Advanced poorly differentiated adenocarcinoma of the colon with micropapillary carcinoma components except specific cytokeratin expressions, report of a case].
Author: Takahashi, Sho|Kuroiwa, Ganji|Hirayama, Michiaki|Tobioka, Hirotoshi
PMID: 22139489
Journal: Harefuah. 2011 Apr;150(4):392-6, 416.
Title: [Management of hereditary non-polyposis syndrome (Lynch syndrome)].
Author: Kariv, Revital|Goldberg, Yael|Soler, Irit|Rosner, Gie|Half, Elizabeth|Moshkowitz, Menachem|Vilkin, Alex|Levi, Zohar|Niv, Yaron
PMID: 22164924
Journal: Acta Gastroenterol Latinoam. 2011 Sep;41(3):247-61.
Title: [Genetics and epigenetics of colorectal cancer].
Author: Pellegrini, Maria Laura|Argibay, Pablo|Gomez, Daniel E
PMID: 22233005
Journal: Indian J Pathol Microbiol. 2011 Oct-Dec;54(4):725-9.
Title: Sporadic colorectal polyps and mismatch repair proteins.
Author: Molaei, Mahsa|Yadollahzadeh, Mahdi|Almasi, Shohreh|Shivarani, Sepideh|Fatemi, Seyed Reza|Zali, Mohammad Reza
PMID: 22234098
Journal: Chirurgia (Bucur). 2011 Nov-Dec;106(6):775-80.
Title: [Immunohistochemical screening of hMLH1 and hMSH2 gene mutations in patients diagnosed with colorectal cancer and microsatellite instability suspicion].
Author: Muresan, F|Simescu, R|Domsa, I|Buiga, R|Cazacu, M
PMID: 22308916
Journal: Clin Epigenetics. 2011 Apr;2(1):1-5.
Title: Association between hMLH1 hypermethylation and JC virus (JCV) infection in human colorectal cancer (CRC).
Author: Vilkin, Alex|Niv, Yaron
PMID: 22704265
Journal: Radiol Oncol. 2011 Jun;45(2):75-81.
Title: Microsatellite instability in colorectal cancer.
Author: Horvat, Matej|Stabuc, Borut
PMID: 22933939
Journal: Exp Ther Med. 2011 Jul;2(4):695-700.
Title: Sessile serrated adenoma shares similar genetic and epigenetic features with microsatellite unstable colon cancer in a location-dependent manner.
Author: Maeda, Takafumi|Suzuki, Koichi|Togashi, Kazutomo|Nokubi, Mitsuhiro|Saito, Masaaki|Tsujinaka, Shingo|Kamiyama, Hidenori|Konishi, Fumio
PMID: 22977561
Journal: Balkan J Med Genet. 2011 Dec;14(2):25-34.
Title: Alterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancer.
Author: Onrat, St|Ceken, I|Ellidokuz, E|Kupelioglu, A
PMID: 24052709
Journal: Int J Cancer. 2012 Mar 15;130(6):1367-77.
Title: Evaluation of predictive models in daily practice for the identification of patients with Lynch syndrome.
Author: Tresallet, Christophe|Brouquet, Antoine|Julie, Catherine|Beauchet, Alain|Vallot, Celine|Menegaux, Fabrice|Mitry, Emmanuel|Radvanyi, Francois|Malafosse, Robert|Rougier, Philippe|Nordlinger, Bernard|Laurent-Puig, Pierre|Boileau, Catherine|Emile, Jean-Franco
PMID: 21520036
Journal: Genome Res. 2012 Feb;22(2):271-82.
Title: Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Author: Hinoue, Toshinori|Weisenberger, Daniel J|Lange, Christopher P E|Shen, Hui|Byun, Hyang-Min|Van Den Berg, David|Malik, Simeen|Pan, Fei|Noushmehr, Houtan|van Dijk, Cornelis M|Tollenaar, Rob A E M|Laird, Peter W
PMID: 21659424
Journal: Mol Biol Rep. 2012 Mar;39(3):2553-60.
Title: Association between methylation in mismatch repair genes, V600E BRAF mutation and microsatellite instability in colorectal cancer patients.
Author: Rasuck, Carla G|Leite, Sinara M O|Komatsuzaki, Flavia|Ferreira, Alessandro C S|Oliveira, Vanessa C|Gomes, Karina B
PMID: 21681432
Journal: J Gastrointest Cancer. 2012 Jun;43(2):209-14.
Title: Loss of expression of DNA mismatch repair proteins in aberrant crypt foci identified in vivo by magnifying colonoscopy in subjects with hereditary nonpolyposic and sporadic colon rectal cancer.
Author: Ramirez-Ramirez, Miguel Angel|Sobrino-Cossio, Sergio|de la Mora-Levy, Jose Guillermo|Hernandez-Guerrero, Angelica|Macedo-Reyes, Veronica de Jesus|Maldonado-Martinez, Hector Aquiles|Alonso-Larraga, Juan Octavio|Ramirez-Solis, Mauro Eduardo
PMID: 21744313
Journal: Int J Surg Pathol. 2012 Apr;20(2):185-90.
Title: Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Author: Remo, Andrea|Zanella, Caterina|Molinari, Enrico|Talamini, Alberto|Tollini, Filippo|Piacentini, Paolo|Battaglia, Paolo|Baritono, Elisabetta|Bonetti, Andrea|Lanza, Franco|Fasolin, Antonio|Manfrin, Erminia|Vendraminelli, Roberto
PMID: 21791485
Journal: Dig Dis Sci. 2012 Jan;57(1):79-84.
Title: Presence of JC virus DNA in the tumor tissue and normal mucosa of patients with sporadic colorectal cancer (CRC) or with positive family history and Bethesda criteria.
Author: Vilkin, Alex|Ronen, Ziv|Levi, Zohar|Morgenstern, Sara|Halpern, Marisa|Niv, Yaron
PMID: 21830098
Journal: Gut. 2012 Jun;61(6):865-72.
Title: Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer.
Author: Perez-Carbonell, Lucia|Ruiz-Ponte, Clara|Guarinos, Carla|Alenda, Cristina|Paya, Artemio|Brea, Alejandro|Egoavil, Cecilia M|Castillejo, Adela|Barbera, Victor M|Bessa, Xavier|Xicola, Rosa M|Rodriguez-Soler, Maria|Sanchez-Fortun, Cristina|Acame, Nuria|Castel
PMID: 21868491
Journal: Ann Surg Oncol. 2012 Mar;19(3):809-16.
Title: Screening for Lynch syndrome in colorectal cancer: are we doing enough?
Author: Canard, Guillaume|Lefevre, Jeremie H|Colas, Chrystelle|Coulet, Florence|Svrcek, Magali|Lascols, Olivier|Hamelin, Richard|Shields, Conor|Duval, Alex|Flejou, Jean-Francois|Soubrier, Florent|Tiret, Emmanuel|Parc, Yann
PMID: 21879275
Journal: Fam Cancer. 2012 Mar;11(1):13-7.
Title: Two novel mutations in hMLH1 gene in Iranian hereditary non-polyposis colorectal cancer patients.
Author: Shahmoradi, Somayeh|Bidmeshkipour, Ali|Salamian, Ahmad|Emami, Mohammad Hasan|Kazemi, Zahra|Salehi, Mansoor
PMID: 21901500
Journal: Cancer Epidemiol. 2012 Apr;36(2):183-9.
Title: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.
Author: Reeves, Stuart G|Meldrum, Cliff|Groombridge, Claire|Spigelman, Allan|Suchy, Janina|Kurzawski, Grzegorz|Lubinski, Jan|Scott, Rodney J
PMID: 21974800
Journal: Pediatr Dev Pathol. 2012 May-Jun;15(3):192-8.
Title: Colorectal adenocarcinoma: a pediatric case review with a focus on mismatch repair gene mutations and E-cadherin expression.
Author: Gonzalez, Raul S|Shulman, Sarah C|Katzenstein, Howard M|Steelman, Charlotte K|Wulkan, Mark L|Abramowsky, Carlos R|Cohen, Cynthia|Davis, Gigi K|Shehata, Bahig M
PMID: 21985494
Journal: J Gastrointest Cancer. 2012 Sep;43(3):518-20.
Title: Right colon cancer missed by virtual colonoscopy in HNPCC patient.
Author: Baiocchi, G L|Mazza, G|Baronchelli, C|Marchina, E|Tiberio, G A M|Grazioli, L|Portolani, N|Giulini, S M
PMID: 21987022
Journal: Colorectal Dis. 2012 Mar;14(3):e80-9.
Title: A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer.
Author: Zhang, R|Qin, W|Xu, G-L|Zeng, F-F|Li, C-X
PMID: 21988782
Journal: J Comp Pathol. 2012 Jul;147(1):24-30.
Title: Widespread mismatch repair expression in feline small intestinal lymphomas.
Author: Aberdein, D|Munday, J S|Howe, L|French, A F|Gibson, I R
PMID: 22000951
Journal: Mol Carcinog. 2012 Dec;51(12):1003-8.
Title: Assessment of three epigenotypes in colorectal cancer by combined bisulfite restriction analysis.
Author: Karpinski, Pawel|Szmida, Elzbieta|Misiak, Blazej|Ramsey, David|Leszczynski, Przemyslaw|Bebenek, Marek|Sedziak, Tomasz|Grzebieniak, Zygmunt|Jonkisz, Anna|Lebioda, Arleta|Sasiadek, Maria M
PMID: 22006538
Journal: J Pathol. 2012 Apr;226(5):764-74.
Title: Yield of routine molecular analyses in colorectal cancer patients
Author: van Lier, Margot G F|Leenen, Celine H M|Wagner, Anja|Ramsoekh, Dewkoemar|Dubbink, Hendrikus J|van den Ouweland, Ans M W|Westenend, Pieter J|de Graaf, Eelco J R|Wolters, Leonieke M M|Vrijland, Wietske W|Kuipers, Ernst J|van Leerdam, Monique E|Steyerberg, E
PMID: 22081473
Journal: Fam Cancer. 2012 Mar;11(1):19-26.
Title: Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors.
Author: Rahner, Nils|Brockschmidt, Felix F|Steinke, Verena|Kahl, Philip|Becker, Tim|Vasen, Hans F A|Wijnen, Juul T|Tops, Carli J M|Holinski-Feder, Elke|Ligtenberg, Marjolijn J L|Spruijt, Liesbeth|Gorgens, Heike|Stemmler, Susanne|Kloor, Matthias|Dietmaier, Wolfgan
PMID: 22086303
Journal: Int J Colorectal Dis. 2012 May;27(5):647-56.
Title: T([20]) repeat in the 3'-untranslated region of the MT1X gene: a marker with high sensitivity and specificity to detect microsatellite instability in colorectal cancer.
Author: Morandi, Luca|de Biase, Dario|Visani, Michela|Monzoni, Adriana|Tosi, Annalisa|Brulatti, Mauro|Turchetti, Daniela|Baccarini, Paola|Tallini, Giovanni|Pession, Annalisa
PMID: 22108904
Journal: Fam Cancer. 2012 Mar;11(1):1-6.
Title: A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours.
Author: Schofield, Lyn|Grieu, Fabienne|Goldblatt, Jack|Amanuel, Benhur|Iacopetta, Barry
PMID: 22120844
Journal: Cancer Prev Res (Phila). 2012 Feb;5(2):328-35.
Title: Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.
Author: Levine, A Joan|Win, Aung Ko|Buchanan, Daniel D|Jenkins, Mark A|Baron, John A|Young, Joanne P|Long, Tiffany I|Weisenberger, Daniel J|Laird, Peter W|McCall, Rebecca L|Duggan, David J|Haile, Robert W
PMID: 22144422
Journal: Dig Dis Sci. 2012 May;57(5):1261-70.
Title: Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7.
Author: Kaji, Eisuke|Uraoka, Toshio|Kato, Jun|Hiraoka, Sakiko|Suzuki, Hideyuki|Akita, Mitsuhiro|Saito, Shunsuke|Tanaka, Takehiro|Ohara, Nobuya|Yamamoto, Kazuhide
PMID: 22173745
Journal: Am J Surg Pathol. 2012 Feb;36(2):163-72.
Title: Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability.
Author: Aysal, Anil|Karnezis, Anthony|Medhi, Irum|Grenert, James P|Zaloudek, Charles J|Rabban, Joseph T
PMID: 22189970
Journal: Fam Cancer. 2012 Jun;11(2):243-7.
Title: The founder Ashkenazi Jewish mutations in the MSH2 and MSH6 genes in Israeli patients with gastric and pancreatic cancer.
Author: Laitman, Yael|Herskovitz, Liron|Golan, Talia|Kaufman, Bella|Paluch, Shani Shimon|Friedman, Eitan
PMID: 22219001
Journal: Mod Pathol. 2012 Apr;25(4):590-601.
Title: Unique genetic profile of sporadic colorectal cancer liver metastasis versus primary tumors as defined by high-density single-nucleotide polymorphism arrays.
Author: Munoz-Bellvis, Luis|Fontanillo, Celia|Gonzalez-Gonzalez, Maria|Garcia, Eva|Iglesias, Manuel|Esteban, Carmen|Gutierrez, M L|Abad, M M|Bengoechea, Oscar|De Las Rivas, Javier|Orfao, Alberto|Sayagues, J M
PMID: 22222638
Journal: Genet Test Mol Biomarkers. 2012 May;16(5):388-95.
Title: Mapping of microsatellite instability in endoscopic normal colon.
Author: Tug, Esra|Balaban, Yasemin H|Sahin, Ebru Kaplan
PMID: 22224632
Journal: World J Gastroenterol. 2012 Jan 7;18(1):70-8.
Title: Germline promoter hypermethylation of tumor suppressor genes in gastric cancer.
Author: Wu, Pu-Yuan|Zhang, Zheng|Wang, Jing-Mei|Guo, Wen-Wen|Xiao, Nong|He, Qiong|Wang, Ya-Ping|Fan, Yi-Mei
PMID: 22228973
Journal: Am J Gastroenterol. 2012 Mar;107(3):460-9.
Title: A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma.
Author: Kimura, Tomoaki|Yamamoto, Eiichiro|Yamano, Hiro-O|Suzuki, Hiromu|Kamimae, Seiko|Nojima, Masanori|Sawada, Takeshi|Ashida, Masami|Yoshikawa, Kenjiro|Takagi, Ryo|Kato, Ryusuke|Harada, Taku|Suzuki, Ryo|Maruyama, Reo|Kai, Masahiro|Imai, Kohzoh|Shinomura, Yasuh
PMID: 22233696
Journal: BMC Cancer. 2012 Jan 13;12:12.
Title: Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method.
Author: Tournier, Benjamin|Chapusot, Caroline|Courcet, Emilie|Martin, Laurent|Lepage, Come|Faivre, Jean|Piard, Francoise
PMID: 22243995
Journal: Int J Colorectal Dis. 2012 Jul;27(7):911-9.
Title: Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability.
Author: Plaschke, Jens|Preussler, Mark|Ziegler, Andreas|Schackert, Hans K
PMID: 22249440
Journal: Cancer Lett. 2012 Jul 1;320(1):56-64.
Title: Proliferation rate but not mismatch repair affects the long-term response of colon carcinoma cells to 5FU treatment.
Author: Choudhary, B|Hanski, M L|Zeitz, M|Hanski, C
PMID: 22266192
Journal: Eur J Hum Genet. 2012 Jul;20(7):762-8.
Title: MLH1 promoter hypermethylation in the analytical algorithm of Lynch syndrome: a cost-effectiveness study.
Author: Gausachs, Mireia|Mur, Pilar|Corral, Julieta|Pineda, Marta|Gonzalez, Sara|Benito, Llucia|Menendez, Mireia|Espinas, Josep Alfons|Brunet, Joan|Iniesta, Maria Dolores|Gruber, Stephen B|Lazaro, Conxi|Blanco, Ignacio|Capella, Gabriel
PMID: 22274583
Journal: Histopathology. 2012 Feb;60(3):416-26.
Title: A simple immunohistochemical algorithm predicts the risk of distant metastases in right-sided colon cancer.
Author: Neumann, Jens|Horst, David|Kriegl, Lydia|Maatz, Susanne|Engel, Jutta|Jung, Andreas|Kirchner, Thomas
PMID: 22276605
Journal: Tumour Biol. 2012 Jun;33(3):857-64.
Title: Clinical and molecular detection of inherited colorectal cancers in northeast Italy: a first prospective study of incidence of Lynch syndrome and MUTYH-related colorectal cancer in Italy.
Author: Urso, E|Agostini, M|Pucciarelli, S|Rugge, M|Bertorelle, R|Maretto, I|Bedin, C|D'Angelo, E|Mescoli, C|Zorzi, M|Viel, A|Bruttocao, G|Ferraro, B|Erroi, F|Contin, P|De Salvo, G L|Nitti, D
PMID: 22278153
Journal: Genet Test Mol Biomarkers. 2012 May;16(5):406-11.
Title: High-resolution melting analyses for gene scanning of APC, MLH1, MSH2, and MSH6 associated with hereditary colorectal cancer.
Author: Obul, Jurat|Itoga, Sakae|Abliz, Maynur|Sato, Kenichi|Ishige, Takayuki|Utsuno, Emi|Matsushita, Kazuyuki|Matsubara, Hisahiro|Nomura, Fumio
PMID: 22283331
Journal: Int J Cancer. 2012 Oct 15;131(8):1828-36.
Title: Loss of HLA class I and mismatch repair protein expression in sporadic endometrioid endometrial carcinomas.
Author: de Jong, Renske A|Boerma, Annemarie|Boezen, H Marike|Mourits, Marian J E|Hollema, Harry|Nijman, Hans W
PMID: 22287095
Journal: Int J Cancer. 2012 Oct 15;131(8):1790-9.
Title: Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.
Author: Garcia-Solano, J|Conesa-Zamora, P|Carbonell, P|Trujillo-Santos, J|Torres-Moreno D, D|Pagan-Gomez, I|Rodriguez-Braun, E|Perez-Guillermo, M
PMID: 22287190
Journal: Mutagenesis. 2012 Mar;27(2):219-23.
Title: Investigation of the effects of DNA repair gene polymorphisms on the risk of colorectal cancer.
Author: Tomlinson, Ian P M|Houlston, Richard S|Montgomery, Grant W|Sieber, Oliver M|Dunlop, Malcolm G
PMID: 22294770
Journal: Int J Clin Exp Pathol. 2012;5(1):105-9. Epub 2012 Jan 5.
Title: Lymphoepithelioma-like carcinoma of the colon.
Author: Delaney, David|Chetty, Runjan
PMID: 22295155
Journal: Clin Cancer Res. 2012 Mar 15;18(6):1506-12.
Title: Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications.
Author: Sinicrope, Frank A|Sargent, Daniel J
PMID: 22302899
Journal: Diagn Mol Pathol. 2012 Mar;21(1):24-33.
Title: Methylation variable position profiles of hMLH1 promoter CpG islands in human sporadic colorectal carcinoma.
Author: Huang, Qing|Huang, Jun-Fu|Zhang, Bo|Baum, Larry|Fu, Wei-Ling
PMID: 22306672
Journal: BMC Cancer. 2012 Feb 9;12:64.
Title: Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries.
Author: Monteiro Santos, Erika Maria|Valentin, Mev Dominguez|Carneiro, Felipe|de Oliveira, Ligia Petrolini|de Oliveira Ferreira, Fabio|Junior, Samuel Aguiar|Nakagawa, Wilson Toshihiko|Gomy, Israel|de Faria Ferraz, Victor Evangelista|da Silva Junior, Wilson Araujo
PMID: 22321913
Journal: Mod Pathol. 2012 May;25(5):722-30.
Title: Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry.
Author: Walsh, Michael D|Buchanan, Daniel D|Pearson, Sally-Ann|Clendenning, Mark|Jenkins, Mark A|Win, Aung Ko|Walters, Rhiannon J|Spring, Kevin J|Nagler, Belinda|Pavluk, Erika|Arnold, Sven T|Goldblatt, Jack|George, Jill|Suthers, Graeme K|Phillips, Kerry|Hopper, J
PMID: 22322191
Journal: J Clin Oncol. 2012 Mar 20;30(9):958-64.
Title: Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study.
Author: Win, Aung Ko|Young, Joanne P|Lindor, Noralane M|Tucker, Katherine M|Ahnen, Dennis J|Young, Graeme P|Buchanan, Daniel D|Clendenning, Mark|Giles, Graham G|Winship, Ingrid|Macrae, Finlay A|Goldblatt, Jack|Southey, Melissa C|Arnold, Julie|Thibodeau, Stephen N
PMID: 22331944
Journal: PLoS One. 2012;7(2):e31863.
Title: C-terminal fluorescent labeling impairs functionality of DNA mismatch repair proteins.
Author: Brieger, Angela|Plotz, Guido|Hinrichsen, Inga|Passmann, Sandra|Adam, Ronja|Zeuzem, Stefan
PMID: 22348133
Journal: Br J Cancer. 2012 Mar 13;106(6):1239-45.
Title: Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial.
Author: Tikidzhieva, A|Benner, A|Michel, S|Formentini, A|Link, K-H|Dippold, W|von Knebel Doeberitz, M|Kornmann, M|Kloor, M
PMID: 22353804
Journal: J Clin Oncol. 2012 Apr 1;30(10):1058-63.
Title: Reflex immunohistochemistry and microsatellite instability testing of colorectal tumors for Lynch syndrome among US cancer programs and follow-up of abnormal results.
Author: Beamer, Laura C|Grant, Marcia L|Espenschied, Carin R|Blazer, Kathleen R|Hampel, Heather L|Weitzel, Jeffrey N|MacDonald, Deborah J
PMID: 22355048
Journal: Methods Mol Biol. 2012;863:3-14.
Title: Epigenetic markers of early tumor development.
Author: Dumitrescu, Ramona G
PMID: 22359284
Journal: J Med Genet. 2012 Mar;49(3):151-7.
Title: Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification.
Author: Parsons, Michael T|Buchanan, Daniel D|Thompson, Bryony|Young, Joanne P|Spurdle, Amanda B
PMID: 22368298
Journal: World J Surg Oncol. 2012 Feb 29;10:47.
Title: ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics.
Author: Levidou, Georgia|Saetta, Angelica A|Gigelou, Fanie|Karlou, Maria|Papanastasiou, Polyanthi|Stamatelli, Angeliki|Kavantzas, Nikolaos|Michalopoulos, Nikolaos V|Agrogiannis, George|Patsouris, Efstratios|Korkolopoulou, Penelope
PMID: 22376079
Journal: Pathobiology. 2012;79(3):162-8.
Title: Mismatch repair proteins hMLH1 and hMSH2 are differently expressed in the three main subtypes of sporadic renal cell carcinoma.
Author: Stoehr, Christine|Burger, Maximilian|Stoehr, Robert|Bertz, Simone|Ruemmele, Petra|Hofstaedter, Ferdinand|Denzinger, Stefan|Wieland, Wolf F|Hartmann, Arndt|Walter, Bernhard
PMID: 22378480
Journal: Fam Cancer. 2012 Sep;11(3):519-24.
Title: Q48P mutation in the hMLH1 gene associated with Lynch syndrome in three Hungarian families.
Author: Tanyi, Miklos|Olasz, Judit|Tanyi, Janos L|Toth, Laszlo|Antal-Szalmas, Peter|Buban, Tamas|Andras, Csilla|Urbancsek, Hilda|Garami, Zoltan|Csuka, Orsolya|Damjanovich, Laszlo
PMID: 22395473
Journal: Hepatogastroenterology. 2012 Jun;59(116):1091-7.
Title: Correlations between clinicopathological parameters and molecular signatures of primary tumors for patients with stage T3n0 colorectal adenocarcinomas: a single center retrospective study on 100 cases.
Author: Andras, Csilla|Toth, Laszlo|Molnar, Csaba|Tanyi, Miklos|Csiki, Zoltan|Dezso, Balazs|Posan, Janos|Shemirani, Amir-Houshang|Csiki, Emese|Szanto, Janos
PMID: 22414548
Journal: J Mol Diagn. 2012 May-Jun;14(3):264-73.
Title: The germline MLH1 K618A variant and susceptibility to Lynch syndrome-associated tumors.
Author: Medeiros, Fabiola|Lindor, Noralane M|Couch, Fergus J|Highsmith, W Edward Jr
PMID: 22426235
Journal: Cancer Lett. 2012 Sep 28;322(2):204-12.
Title: Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation.
Author: Kikuyama, Mizuho|Takeshima, Hideyuki|Kinoshita, Takayuki|Okochi-Takada, Eriko|Wakabayashi, Mika|Akashi-Tanaka, Sadako|Ogawa, Toshihisa|Seto, Yasuyuki|Ushijima, Toshikazu
PMID: 22433712
Journal: Jpn J Clin Oncol. 2012 May;42(5):451-4.
Title: Development of invasive colon cancer with microsatellite instability in a patient with hyperplastic polyposis syndrome.
Author: Horii, Joichiro|Kato, Jun|Nagasaka, Takeshi|Hiraoka, Sakiko|Sun, Dong-Sheng|Watanabe, Kazuo|Fujita, Isao|Toyokawa, Tatsuya|Tomoda, Jun|Yamamoto, Kazuhide
PMID: 22438407
Journal: BMC Gastroenterol. 2012 Mar 23;12:24.
Title: Metachronous metastasis- and survival-analysis show prognostic importance of lymphadenectomy for colon carcinomas.
Author: Laubert, Tilman|Habermann, Jens K|Hemmelmann, Claudia|Kleemann, Markus|Oevermann, Elisabeth|Bouchard, Ralf|Hildebrand, Philipp|Jungbluth, Thomas|Burk, Conny|Esnaashari, Hamed|Schloricke, Erik|Hoffmann, Martin|Ziegler, Andreas|Bruch, Hans-Peter|Roblick, Uw
PMID: 22443372
Journal: Exp Oncol. 2012;34(1):49-52.
Title: Novel germline MLH1 and MSH2 mutations in Latvian Lynch syndrome families.
Author: Berzina, D|Irmejs, A|Kalniete, D|Borosenko, V|Nakazawa-Miklasevica, M|Ribenieks, K|Trofimovics, G|Gardovskis, J|Miklasevics, E
PMID: 22453149
Journal: Hepatogastroenterology. 2012 Oct;59(119):2228-32.
Title: Expression of hMLH1, hMSH2 and hMSH6 in small intestinal carcinomas.
Author: Gu, Mi Jin|Bae, Young Kyung|Kim, Aeri|Hong, Seung-Mo|Yu, Eunsil|Kim, Jihun|Jang, Kee-Taek|Chang, Hee-Kyung|Jung, Eun Sun|Bae, Han-Ik|Yoon, Ghil Suk|Kim, Joon Mee|Kim, Jung Yeon|Kim, Gwang Il|Oh, Young-Ha|Jang, Kyu Yun|Jun, Sun-Young|Eom, Dae Woon|Kwon, Ky
PMID: 22456432
Journal: Dig Liver Dis. 2012 Jun;44(6):515-22.
Title: Simplified identification of Lynch syndrome: a prospective, multicenter study.
Author: Bonnet, Delphine|Selves, Janick|Toulas, Christine|Danjoux, Marie|Duffas, Jean Pierre|Portier, Guillaume|Kirzin, Sylvain|Ghouti, Laurent|Carrere, Nicolas|Suc, Bertrand|Alric, Laurent|Barange, Karl|Buscail, Louis|Chaubard, Thierry|Imani, Kamran|Guimbaud, Ro
PMID: 22480969
Journal: Rev Col Bras Cir. 2012;39(1):48-53.
Title: Evaluation of the expression of the MGMT gene in normal and neoplastic tissue of patients with colorectal cancer.
Author: Cordeiro, Adriana Teixeira|Silva, Camila Morais Goncalves da|Bartchewsky Junior, Waldemar|Ribeiro, Marcelo Lima|Martinez, Carlos Augusto Real
PMID: 22481706
Journal: Appl Immunohistochem Mol Morphol. 2012 Oct;20(5):470-7.
Title: MSH6 mutations are frequent in hereditary nonpolyposis colorectal cancer families with normal pMSH6 expression as detected by immunohistochemistry.
Author: Okkels, Henrik|Lindorff-Larsen, Karen|Thorlasius-Ussing, Ole|Vyberg, Mogens|Lindebjerg, Jan|Sunde, Lone|Bernstein, Inge|Klarskov, Louise|Holck, Susanne|Krarup, Henrik Bygum
PMID: 22495361
Journal: Am J Surg Pathol. 2012 Jun;36(6):876-82.
Title: Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics.
Author: Rosty, Christophe|Buchanan, Daniel D|Walsh, Michael D|Pearson, Sally-Ann|Pavluk, Erika|Walters, Rhiannon J|Clendenning, Mark|Spring, Kevin J|Jenkins, Mark A|Win, Aung K|Hopper, John L|Sweet, Kevin|Frankel, Wendy L|Aronson, Melyssa|Gallinger, Steve|Goldbla
PMID: 22510757
Journal: Int J Hyperthermia. 2012;28(3):191-201.
Title: Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines.
Author: Nadin, Silvina B|Cuello-Carrion, F Dario|Sottile, Mayra L|Ciocca, Daniel R|Vargas-Roig, Laura M
PMID: 22515340
Journal: Ann Surg Oncol. 2012 Oct;19(11):3627-35.
Title: FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer.
Author: Nakanishi, Ryota|Kitao, Hiroyuki|Fujinaka, Yoshihiko|Yamashita, Nami|Iimori, Makoto|Tokunaga, Eriko|Yamashita, Natsumi|Morita, Masaru|Kakeji, Yoshihiro|Maehara, Yoshihiko
PMID: 22526901
Journal: Lancet Oncol. 2012 Jun;13(6):598-606.
Title: Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study.
Author: Kloor, Matthias|Huth, Cathrin|Voigt, Anita Y|Benner, Axel|Schirmacher, Peter|von Knebel Doeberitz, Magnus|Blaker, Hendrik
PMID: 22552011
Journal: Hum Mutat. 2012 Aug;33(8):1294-301.
Title: Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients.
Author: Kantelinen, Jukka|Kansikas, Minttu|Candelin, Satu|Hampel, Heather|Smith, Betsy|Holm, Liisa|Kariola, Reetta|Nystrom, Minna
PMID: 22581703
Journal: J Biomed Biotechnol. 2012;2012:826178.
Title: Prevention of chronic experimental colitis induced by dextran sulphate sodium (DSS) in mice treated with FR91.
Author: Lombardi, Valter R M|Etcheverria, Ignacio|Carrera, Ivan|Cacabelos, Ramon|Chacon, Antonio R
PMID: 22619498
Journal: Patholog Res Int. 2012;2012:350309.
Title: Clinicopathological features and management of cancers in lynch syndrome.
Author: Aarnio, Markku
PMID: 22619739
Journal: Front Oncol. 2012 Feb 27;2:7.
Title: Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.
Author: Zlobec, Inti|Bihl, Michel P|Foerster, Anja|Rufle, Alex|Terracciano, Luigi|Lugli, Alessandro
PMID: 22655257
Journal: J Mol Diagn. 2012 Jul;14(4):357-66.
Title: ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing.
Author: Pritchard, Colin C|Smith, Christina|Salipante, Stephen J|Lee, Ming K|Thornton, Anne M|Nord, Alex S|Gulden, Cassandra|Kupfer, Sonia S|Swisher, Elizabeth M|Bennett, Robin L|Novetsky, Akiva P|Jarvik, Gail P|Olopade, Olufunmilayo I|Goodfellow, Paul J|King, Ma
PMID: 22658618
Journal: Dig Dis Sci. 2012 Nov;57(11):2863-72.
Title: Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia.
Author: Abdul Murad, Nor Azian|Othman, Zulhabri|Khalid, Melati|Abdul Razak, Zuraini|Hussain, Rosniza|Nadesan, Sukumar|Sagap, Ismail|Mohamed Rose, Isa|Wan Ngah, Wan Zurinah|Jamal, Rahman
PMID: 22669205
Journal: Fam Cancer. 2012 Sep;11(3):441-7.
Title: Cancer spectrum in DNA mismatch repair gene mutation carriers: results from a hospital based Lynch syndrome registry.
Author: Pande, Mala|Wei, Chongjuan|Chen, Jinyun|Amos, Christopher I|Lynch, Patrick M|Lu, Karen H|Lucio, Laura A|Boyd-Rogers, Stephanie G|Bannon, Sarah A|Mork, Maureen E|Frazier, Marsha L
PMID: 22714864
Journal: World J Gastroenterol. 2012 Jun 14;18(22):2745-55.
Title: Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer.
Author: Yamamoto, Hiroyuki|Adachi, Yasushi|Taniguchi, Hiroaki|Kunimoto, Hiroaki|Nosho, Katsuhiko|Suzuki, Hiromu|Shinomura, Yasuhisa
PMID: 22719182
Journal: Int J Oncol. 2012 Sep;41(3):793-7.
Title: Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review).
Author: Banno, Kouji|Kisu, Iori|Yanokura, Megumi|Tsuji, Kosuke|Masuda, Kenta|Ueki, Arisa|Kobayashi, Yusuke|Yamagami, Wataru|Nomura, Hiroyuki|Tominaga, Eiichiro|Susumu, Nobuyuki|Aoki, Daisuke
PMID: 22735547
Journal: World J Gastrointest Pathophysiol. 2012 Jun 15;3(3):71-9.
Title: Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer.
Author: Hassen, Samar|Ali, Nawab|Chowdhury, Parimal
PMID: 22737591
Journal: Oncol Lett. 2012 Feb;3(2):441-444.
Title: MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3'-deoxyadenosine) in vitro.
Author: Imesch, Patrick|Goerens, Anouk|Fink, Daniel|Fedier, Andre
PMID: 22740928
Journal: Oncol Lett. 2012 Mar;3(3):565-570.
Title: PIK3CA mutation and methylation influences the outcome of colorectal cancer.
Author: Iida, Satoru|Kato, Shunsuke|Ishiguro, Megumi|Matsuyama, Takatoshi|Ishikawa, Toshiaki|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Uetake, Hiroyuki|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 22740953
Journal: Clin Endosc. 2012 Mar;45(1):103-7.
Title: A case of colonic mucinous adenocarcinoma in 19-year-old male patient.
Author: Chung, Mi Yeon|Park, Young Sook|Ryu, Sang Ryul|Ahn, Sang Bong|Kim, Seong Hwan|Jo, Yun Ju|Han, Jun Kil|Joo, Jong Eun
PMID: 22741141
Journal: Fam Cancer. 2012 Dec;11(4):559-64.
Title: Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
Author: Takahashi, Masanobu|Furukawa, Yoichi|Shimodaira, Hideki|Sakayori, Masato|Moriya, Takuya|Moriya, Yoshihiro|Nakamura, Yusuke|Ishioka, Chikashi
PMID: 22766992
Journal: Gynecol Obstet Invest. 2012;74(4):324-8.
Title: Asymptomatic synchronous quintuple primary cancers.
Author: Komiyama, Shinichi|Nishio, Eiji|Ichikawa, Ryoko|Miyamura, Hironori|Kawamura, Kyoko|Komiyama, Mizuka|Nishio, Yoshimori|Udagawa, Yasuhiro
PMID: 22776788
Journal: Mol Biol Rep. 2012 Oct;39(10):9307-10.
Title: Soft tissue sarcoma and the hereditary non-polyposis colorectal cancer (HNPCC) syndrome: formulation of an hypothesis.
Author: Urso, E|Agostini, M|Pucciarelli, S|Bedin, C|D'angelo, E|Mescoli, C|Viel, A|Maretto, I|Mammi, I|Nitti, D
PMID: 22782591
Journal: Nature. 2012 Jul 18;487(7407):330-7.
Title: Comprehensive molecular characterization of human colon and rectal cancer.
Author:
PMID: 22810696
Journal: Genet Mol Res. 2012 Aug 13;11(3):2315-20.
Title: MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer.
Author: Muniz-Mendoza, R|Ayala-Madrigal, M L|Partida-Perez, M|Peregrina-Sandoval, J|Leal-Ugarte, E|Macias-Gomez, N|Peralta-Leal, V|Meza-Espinoza, J P|Moreno-Ortiz, J M|Ramirez-Ramirez, R|Suarez-Villanueva, S|Gutierrez-Angulo, M
PMID: 22843073
Journal: Can J Surg. 2012 Oct;55(5):294-300.
Title: Lynch syndrome in a predominantly Afrocentric population: a clinicopathological and genetic study.
Author: Plummer, Joseph M|Chin, Sheray N|Aronson, Melyssa|Graham, Rondell P|Williams, Nadia P|Bapat, Bharati|Wharfe, Gillian|Pollett, Aaron|Gallinger, Steven
PMID: 22854115
Journal: Fam Cancer. 2012 Dec;11(4):579-85.
Title: Cancer risks and immunohistochemical profiles linked to the Danish MLH1 Lynch syndrome founder mutation.
Author: Therkildsen, Christina|Isinger-Ekstrand, Anna|Ladelund, Steen|Nissen, Anja|Rambech, Eva|Bernstein, Inge|Nilbert, Mef
PMID: 22864660
Journal: J Hum Genet. 2012 Nov 26;57(11):709-716.
Title: Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer.
Author: Lefevre, Jeremie H|Bonilla, Carolina|Colas, Chrystelle|Winney, Bruce|Johnstone, Elaine|Tonks, Susan|Day, Tammy|Hutnik, Katarzyna|Boumertit, Abdelhamid|Soubrier, Florent|Midgley, Rachel|Kerr, David|Parc, Yann|Bodmer, Walter F
PMID: 22875147
Journal: J Natl Cancer Inst. 2012 Sep 19;104(18):1363-72. Epub 2012 Aug 28.
Title: Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome.
Author: Win, Aung Ko|Lindor, Noralane M|Young, Joanne P|Macrae, Finlay A|Young, Graeme P|Williamson, Elizabeth|Parry, Susan|Goldblatt, Jack|Lipton, Lara|Winship, Ingrid|Leggett, Barbara|Tucker, Katherine M|Giles, Graham G|Buchanan, Daniel D|Clendenning, Mark|Rost
PMID: 22933731
Journal: APMIS. 2012 Oct;120(10):819-27.
Title: Limitations of tissue micro array in Duke's B colon cancer.
Author: Kjaer-Frifeldt, Sanne|Lindebjerg, Jan|Brunner, Nils|Garm Spindler, Karen-Lise|Jakobsen, Anders
PMID: 22958290
Journal: Tunis Med. 2012 Aug-Sep;90(8-9):646-53.
Title: Evaluation of microsatellite instability, MLH1 expression and hMLH1 promoter hypermethylation in colorectal carcinomas among Tunisians patients.
Author: Kria Ben Mahmoud, Lilia|Arfaoui, Amira|Khiari, Mariem|Chaar, Ines|Lounis, Amine|Sammoud, Souraya|Ben Hmida, Abdel Majid|Gharbi, Lasaad|Mzabi, Sabeh Regaya|Bouraoui, Saadia
PMID: 22987381
Journal: Am J Surg Pathol. 2012 Nov;36(11):1700-8.
Title: DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors.
Author: Wen, Yong H|Brogi, Edi|Zeng, Zhaoshi|Akram, Muzaffar|Catalano, Jeff|Paty, Philip B|Norton, Larry|Shia, Jinru
PMID: 22992699
Journal: Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2069-75.
Title: Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer.
Author: Dallol, Ashraf|Al-Maghrabi, Jaudah|Buhmeida, Abdelbaset|Gari, Mamdooh A|Chaudhary, Adeel G|Schulten, Hans-Juergen|Abuzenadah, Adel M|Al-Ahwal, Mahmoud S|Sibiany, Abdulrahman|Al-Qahtani, Mohammed H
PMID: 23010642
Journal: Br J Cancer. 2012 Nov 6;107(10):1783-90.
Title: Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.
Author: Pal, T|Akbari, M R|Sun, P|Lee, J-H|Fulp, J|Thompson, Z|Coppola, D|Nicosia, S|Sellers, T A|McLaughlin, J|Risch, H A|Rosen, B|Shaw, P|Schildkraut, J|Narod, S A
PMID: 23047549
Journal: PLoS One. 2012;7(9):e45357.
Title: A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.
Author: Antelo, Marina|Balaguer, Francesc|Shia, Jinru|Shen, Yan|Hur, Keun|Moreira, Leticia|Cuatrecasas, Miriam|Bujanda, Luis|Giraldez, Maria Dolores|Takahashi, Masanobu|Cabanne, Ana|Barugel, Mario Edmundo|Arnold, Mildred|Roca, Enrique Luis|Andreu, Montserrat|Cast
PMID: 23049789
Journal: Anticancer Res. 2012 Oct;32(10):4347-51.
Title: Evaluation of MLH1 I219V polymorphism in unrelated South American individuals suspected of having Lynch syndrome.
Author: Valentin, Mev Dominguez|Da Silva, Felipe Carneiro|Santos, Erika Maria Monteiro|Da Silva, Sabrina Daniela|De Oliveira Ferreira, Fabio|Aguiar Junior, Samuel|Gomy, Israel|Vaccaro, Carlos|Redal, Maria Ana|Della Valle, Adriana|Sarroca, Carlos|Rasmussen, Lene J
PMID: 23060557
Journal: Cancer Res Treat. 2012 Sep;44(3):179-86.
Title: Clinico-pathologic Parameters for Prediction of Microsatellite Instability in Colorectal Cancer.
Author: Jung, Sang-Bong|Lee, Han-Il|Oh, Hoon-Kyu|Shin, Im-Hee|Jeon, Chang-Ho
PMID: 23091444
Journal: World J Gastroenterol. 2012 Oct 21;18(39):5635-9.
Title: A de novo germline MLH1 mutation in a Lynch syndrome patient with discordant immunohistochemical and molecular biology test results.
Author: Airaud, Fabrice|Kury, Sebastien|Valo, Isabelle|Maury, Ingrid|Bonneau, Dominique|Ingster, Olivier|Bezieau, Stephane
PMID: 23112559
Journal: Clin Cancer Res. 2012 Nov 15;18(22):6136-46.
Title: Expression profiling of archival tumors for long-term health studies.
Author: Waldron, Levi|Ogino, Shuji|Hoshida, Yujin|Shima, Kaori|McCart Reed, Amy E|Simpson, Peter T|Baba, Yoshifumi|Nosho, Katsuhiko|Segata, Nicola|Vargas, Ana Cristina|Cummings, Margaret C|Lakhani, Sunil R|Kirkner, Gregory J|Giovannucci, Edward|Quackenbush, John|
PMID: 23136189
Journal: Anticancer Res. 2012 Nov;32(11):4861-4.
Title: Demethylation of the region around exon 2 of MLH1 gene in gastrointestinal cancer.
Author: Tang, Yanping|Liu, Cong|Wang, Xiyin|Liu, Dong|Ingvarsson, Sigurdur|Chen, Huiping
PMID: 23155252
Journal: Anticancer Res. 2012 Nov;32(11):4963-9.
Title: Uncertainty in the utility of immunohistochemistry in mismatch repair protein expression in epithelial ovarian cancer.
Author: Coppola, Domenico|Nicosia, Santo V|Doty, Andrea|Sellers, Thomas A|Lee, Ji-Hyun|Fulp, Jimmy|Thompson, Zachary|Galeb, Sanja|McLaughlin, John|Narod, Steven A|Schildkraut, Joellen|Pal, Tuya
PMID: 23155266
Journal: BMC Cancer. 2012 Nov 20;12:531.
Title: Germline truncating-mutations in BRCA1 and MSH6 in a patient with early onset endometrial cancer.
Author: Kast, Karin|Neuhann, Teresa M|Gorgens, Heike|Becker, Kerstin|Keller, Katja|Klink, Barbara|Aust, Daniela|Distler, Wolfgang|Schrock, Evelin|Schackert, Hans K
PMID: 23164213
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Nov;15(11):1162-5.
Title: [Expression of hMLH1 in rectal intraepithelial neoplasm and early rectal carcinoma].
Author: Xuan, Zhi-xuan|Lin, Guo-le|Yu, Xin-ming|Qiu, Hui-zhong
PMID: 23172530
Journal: PLoS One. 2012;7(11):e50449.
Title: Association between MLH1 -93G>a polymorphism and risk of colorectal cancer.
Author: Wang, Ting|Liu, Yang|Sima, Li|Shi, Liang|Wang, Zhaoming|Ni, Chunhui|Zhang, Zhengdong|Wang, Meilin
PMID: 23226285
Journal: PLoS One. 2012;7(11):e50616.
Title: Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells.
Author: Tseng-Rogenski, Stephanie S|Chung, Heekyung|Wilk, Maike B|Zhang, Shuai|Iwaizumi, Moriya|Carethers, John M
PMID: 23226332
Journal: PLoS One. 2012;7(12):e51531.
Title: MLH1 region polymorphisms show a significant association with CpG island shore methylation in a large cohort of healthy individuals.
Author: Savio, Andrea J|Lemire, Mathieu|Mrkonjic, Miralem|Gallinger, Steven|Zanke, Brent W|Hudson, Thomas J|Bapat, Bharati
PMID: 23240038
Journal: An Sist Sanit Navar. 2012 Sep-Dec;35(3):377-84.
Title: [Tissue expression of mismatch repair proteins and tumor lymphocytic infiltration: prognostic significance in resected colorectal carcinoma].
Author: Borda, F|Martinez-Penuela, J M|Borda, A|Urman, J|Jimenez, J|Zozaya, J M
PMID: 23296218
Journal: PLoS One. 2012;7(12):e52485.
Title: Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas.
Author: Maletzki, Claudia|Stier, Saskia|Gruenert, Ulrike|Gock, Michael|Ostwald, Christiane|Prall, Friedrich|Linnebacher, Michael
PMID: 23300683
Journal: J Nutrigenet Nutrigenomics. 2012;5(6):327-38.
Title: Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma.
Author: Al-Ghnaniem Abbadi, Reyad|Emery, Peter|Pufulete, Maria
PMID: 23328702
Journal: Rev Med Chil. 2012 Sep;140(9):1132-9.
Title: [Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry].
Author: Wielandt, Ana Maria|Zarate, Alejandro J|Hurtado, Claudia|Orellana, Paulina|Alvarez, Karin|Pinto, Eliana|Contreras, Luis|Corvalan, Alejandro|Kronberg, Udo|Lopez-Kostner, Francisco
PMID: 23354634
Journal: Clin Colon Rectal Surg. 2012 Jun;25(2):118-22.
Title: Oncologic management of hereditary colorectal cancer.
Author: Yacoub, George|Nagalla, Srikanth|Aklilu, Mebea
PMID: 23730227
Journal: Turk J Gastroenterol. 2012;23(6):686-90.
Title: Clinical and molecular characterization of colorectal cancer in young Moroccan patients.
Author: Benmoussa, Amal|Badre, Wafaa|Pedroni, Monica|Zamiati, Soumia|Badre, Latifa|Digregorio, Carmela|De Leon, Maurizio Ponz|Nadifi, Selama
PMID: 23794306
Journal: Gastroenterol Hepatol Bed Bench. 2012 Spring;5(2):71-8.
Title: Molecular profile of colorectal cancer in Indonesia: is there another pathway?
Author: Abdullah, Murdani|Sudoyo, Aru Wisaksono|Utomo, Ahmad R|Fauzi, Ahmad|Rani, Abdul Aziz
PMID: 24834203
Journal: Gut. 2013 Feb;62(2):272-9.
Title: Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer.
Author: Kastrinos, Fay|Steyerberg, Ewout W|Balmana, Judith|Mercado, Rowena|Gallinger, Steven|Haile, Robert|Casey, Graham|Hopper, John L|LeMarchand, Loic|Lindor, Noralane M|Newcomb, Polly A|Thibodeau, Stephen N|Syngal, Sapna
PMID: 22345660
Journal: Genet Med. 2013 Jan;15(1):25-35.
Title: Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry.
Author: Ward, Robyn L|Dobbins, Timothy|Lindor, Noralane M|Rapkins, Robert W|Hitchins, Megan P
PMID: 22878509
Journal: Eur Urol. 2013 Feb;63(2):379-85.
Title: Patients with Lynch syndrome mismatch repair gene mutations are at higher risk for not only upper tract urothelial cancer but also bladder cancer.
Author: Skeldon, Sean C|Semotiuk, Kara|Aronson, Melyssa|Holter, Spring|Gallinger, Steven|Pollett, Aaron|Kuk, Cynthia|van Rhijn, Bas|Bostrom, Peter|Cohen, Zane|Fleshner, Neil E|Jewett, Michael A|Hanna, Sally|Shariat, Shahrokh F|Van Der Kwast, Theodorus H|Evans, An
PMID: 22883484
Journal: J Pathol. 2013 Jan;229(1):99-110.
Title: MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes.
Author: Donehower, Lawrence A|Creighton, Chad J|Schultz, Nikolaus|Shinbrot, Eve|Chang, Kyle|Gunaratne, Preethi H|Muzny, Donna|Sander, Chris|Hamilton, Stanley R|Gibbs, Richard A|Wheeler, David
PMID: 22899370
Journal: Int J Colorectal Dis. 2013 Apr;28(4):547-53.
Title: Inhibitory effects of baicalin on orthotopic xenografts of colorectal cancer cells that are deficient in a mismatch repair gene in nude mice.
Author: Yang, Bo-Lin|Chen, Hong-Jin|Chen, Yu-Gen|Gu, Yun-Fei|Zhang, Shu-Peng|Lin, Qiu|Sun, Yu
PMID: 22914965
Journal: Mod Pathol. 2013 Jan;26(1):131-8.
Title: Secondary mutation in a coding mononucleotide tract in MSH6 causes loss of immunoexpression of MSH6 in colorectal carcinomas with MLH1/PMS2 deficiency.
Author: Shia, Jinru|Zhang, Liying|Shike, Moshe|Guo, Min|Stadler, Zsofia|Xiong, Xiaoling|Tang, Laura H|Vakiani, Efsevia|Katabi, Nora|Wang, Hangjun|Bacares, Ruben|Ruggeri, Jeanine|Boland, C Richard|Ladanyi, Marc|Klimstra, David S
PMID: 22918162
Journal: Hum Mutat. 2013 Jan;34(1):255-65.
Title: Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.
Author: Thompson, Bryony A|Greenblatt, Marc S|Vallee, Maxime P|Herkert, Johanna C|Tessereau, Chloe|Young, Erin L|Adzhubey, Ivan A|Li, Biao|Bell, Russell|Feng, Bingjian|Mooney, Sean D|Radivojac, Predrag|Sunyaev, Shamil R|Frebourg, Thierry|Hofstra, Robert M W|Sijmo
PMID: 22949387
Journal: Gastric Cancer. 2013 Jul;16(3):345-54.
Title: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells.
Author: Mori, Ryutaro|Yoshida, Kazuhiro|Tanahashi, Toshiyuki|Yawata, Kazunori|Kato, Junko|Okumura, Naoki|Tsutani, Yasuhiro|Okada, Morihito|Oue, Naohide|Yasui, Wataru
PMID: 22968820
Journal: Fam Cancer. 2013 Mar;12(1):27-33.
Title: Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors.
Author: Sourrouille, Isabelle|Coulet, Florence|Lefevre, Jeremie H|Colas, Chrystelle|Eyries, Melanie|Svrcek, Magali|Bardier-Dupas, Armelle|Parc, Yann|Soubrier, Florent
PMID: 22987205
Journal: Int J Cancer. 2013 Apr 1;132(7):1556-64.
Title: Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers.
Author: Talseth-Palmer, Bente A|Wijnen, Juul T|Brenne, Ingvild S|Jagmohan-Changur, Shantie|Barker, Daniel|Ashton, Katie A|Tops, Carli M|Evans, Tiffany-Jane|McPhillips, Mary|Groombridge, Claire|Suchy, Janina|Kurzawski, Grzegorz|Spigelman, Allan|Moller, Pal|Morreau
PMID: 22987364
Journal: Int J Cancer. 2013 Apr 15;132(8):1800-10.
Title: Molecular patterns in the evolution of serrated lesion of the colorectum.
Author: Gaiser, Timo|Meinhardt, Sandra|Hirsch, Daniela|Killian, Jonathan Keith|Gaedcke, Jochen|Jo, Peter|Ponsa, Immaculada|Miro, Rosa|Ruschoff, Josef|Seitz, Gerhard|Hu, Yue|Camps, Jordi|Ried, Thomas
PMID: 23011871
Journal: Int J Cancer. 2013 May 1;132(9):2209-16.
Title: Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Author: Han, Sae-Won|Lee, Hyun-Jung|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Park, Jae-Gahb|Kang, Gyeong Hoon|Kim, Tae-You
PMID: 23034738
Journal: Hum Pathol. 2013 Apr;44(4):591-7.
Title: Expression of p27, COX-2, MLH1, and MSH2 in young patients with colon carcinoma and correlation with morphologic findings.
Author: Kenney, Barton|Deng, Yanhong|Mitchell, Kisha
PMID: 23084580
Journal: Dig Liver Dis. 2013 Mar;45(3):245-50.
Title: Deficient mismatch repair phenotype is a prognostic factor for colorectal cancer in elderly patients.
Author: Aparicio, Thomas|Schischmanoff, Olivier|Poupardin, Cecile|Soufir, Nadem|Angelakov, Celine|Barrat, Christophe|Levy, Vincent|Choudat, Laurence|Cucherousset, Joel|Boubaya, Marouane|Lagorce, Christine|Guetz, Gaetan Des|Wind, Philippe|Benamouzig, Robert
PMID: 23102497
Journal: Hautarzt. 2013 Apr;64(4):290-4.
Title: [Muir-Torre syndrome with previously undescribed frameshift mutation in the MSH2 gene].
Author: Gilly, B|Unholzer, A|Strobl-Wildemann, G|Haas, C|Starz, H|Welzel, J
PMID: 23229822
Journal: Biosens Bioelectron. 2013 Apr 15;42:503-11.
Title: A novel bisulfite-microfluidic temperature gradient capillary electrophoresis platform for highly sensitive detection of gene promoter methylation.
Author: Zhang, Huidan|Shan, Lianfeng|Wang, Xiaonan|Ma, Qian|Fang, Jin
PMID: 23246658
Journal: Hum Mutat. 2013 Mar;34(3):490-7.
Title: Cancer risks for MLH1 and MSH2 mutation carriers.
Author: Dowty, James G|Win, Aung K|Buchanan, Daniel D|Lindor, Noralane M|Macrae, Finlay A|Clendenning, Mark|Antill, Yoland C|Thibodeau, Stephen N|Casey, Graham|Gallinger, Steve|Marchand, Loic Le|Newcomb, Polly A|Haile, Robert W|Young, Graeme P|James, Paul A|Giles
PMID: 23255516
Journal: Pediatr Blood Cancer. 2013 Jun;60(6):E13-5.
Title: Anaplastic oligodendroglioma in an adolescent with Lynch syndrome.
Author: Heath, John A|Ng, Jessica|Beshay, Victoria|Coleman, Lee|Lo, Patrick|Amor, David J
PMID: 23255519
Journal: Fam Cancer. 2013 Jun;12(2):169-74.
Title: EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients.
Author: Ligtenberg, Marjolijn J L|Kuiper, Roland P|Geurts van Kessel, Ad|Hoogerbrugge, Nicoline
PMID: 23264089
Journal: Clin Epigenetics. 2013 Jan 16;5(1):2.
Title: BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer.
Author: van Roon, Eddy H|Boot, Arnoud|Dihal, Ashwin A|Ernst, Robert F|van Wezel, Tom|Morreau, Hans|Boer, Judith M
PMID: 23324568
Journal: Fam Cancer. 2013 Sep;12(3):567-72.
Title: Splice site mutations in mismatch repair genes and risk of cancer in the general population.
Author: Thomsen, Mette|Nordestgaard, Borge G|Tybjaerg-Hansen, Anne|Bojesen, Stig E
PMID: 23329266
Journal: Gastroenterology. 2013 May;144(5):926-932.e1; quiz e13-4.
Title: Risk of cancer in cases of suspected lynch syndrome without germline mutation.
Author: Rodriguez-Soler, Maria|Perez-Carbonell, Lucia|Guarinos, Carla|Zapater, Pedro|Castillejo, Adela|Barbera, Victor M|Juarez, Miriam|Bessa, Xavier|Xicola, Rosa M|Clofent, Juan|Bujanda, Luis|Balaguer, Francesc|Rene, Josep-Maria|de-Castro, Luisa|Marin-Gabriel, J
PMID: 23354017
Journal: Ann Surg Oncol. 2013 Jun;20(6):1829-36.
Title: Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers.
Author: Win, Aung Ko|Parry, Susan|Parry, Bryan|Kalady, Matthew F|Macrae, Finlay A|Ahnen, Dennis J|Young, Graeme P|Lipton, Lara|Winship, Ingrid|Boussioutas, Alex|Young, Joanne P|Buchanan, Daniel D|Arnold, Julie|Le Marchand, Loic|Newcomb, Polly A|Haile, Robert W|Li
PMID: 23358792
Journal: Mod Pathol. 2013 Jul;26(7):1013-22.
Title: Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status.
Author: Kim, Jung H|Rhee, Ye-Y|Bae, Jeong-M|Kwon, Hyeong-J|Cho, Nam-Y|Kim, Mi J|Kang, Gyeong H
PMID: 23370766
Journal: Colorectal Dis. 2013 Mar;15(3):e118-23.
Title: Incidence of -93 MLH1 promoter polymorphism in familial and sporadic colorectal cancer.
Author: Martinez-Uruena, N|Macias, L|Perez-Cabornero, L|Infante, M|Lastra, E|Cruz, J J|Miner, C|Gonzalez, R|Duran, M
PMID: 23374646
Journal: J Natl Cancer Inst. 2013 Feb 20;105(4):274-9.
Title: Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome.
Author: Win, Aung Ko|Lindor, Noralane M|Winship, Ingrid|Tucker, Katherine M|Buchanan, Daniel D|Young, Joanne P|Rosty, Christophe|Leggett, Barbara|Giles, Graham G|Goldblatt, Jack|Macrae, Finlay A|Parry, Susan|Kalady, Matthew F|Baron, John A|Ahnen, Dennis J|Marchan
PMID: 23385444
Journal: J Clin Med Res. 2013 Feb;5(1):67-9.
Title: A case of syncronised hereditery nonpoliposis colorectal tumor with different hystopathological type and k-ras gene mutation: case report.
Author: Dinc, Bulent|Temel, Halis Musfik
PMID: 23390480
Journal: J Clin Oncol. 2013 Apr 1;31(10):1336-40.
Title: Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center.
Author: Heald, Brandie|Plesec, Thomas|Liu, Xiuli|Pai, Rish|Patil, Deepa|Moline, Jessica|Sharp, Richard R|Burke, Carol A|Kalady, Matthew F|Church, James|Eng, Charis
PMID: 23401454
Journal: Gut. 2013 Jun;62(6):812-23.
Title: Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts.
Author: Vasen, Hans F A|Blanco, Ignacio|Aktan-Collan, Katja|Gopie, Jessica P|Alonso, Angel|Aretz, Stefan|Bernstein, Inge|Bertario, Lucio|Burn, John|Capella, Gabriel|Colas, Chrystelle|Engel, Christoph|Frayling, Ian M|Genuardi, Maurizio|Heinimann, Karl|Hes, Frederi
PMID: 23408351
Journal: Gan To Kagaku Ryoho. 2013 Feb;40(2):143-7.
Title: [A novel genetic disorder of Lynch syndrome - EPCAM gene deletion].
Author: Tomita, Naohiro|Yamano, Tomoki|Matsubara, Nagahide|Tamura, Kazuo
PMID: 23411950
Journal: Appl Immunohistochem Mol Morphol. 2013 Mar;21(2):97-102.
Title: Pathways of colorectal carcinogenesis.
Author: Arends, Mark J
PMID: 23417071
Journal: Diagn Pathol. 2013 Feb 20;8:31.
Title: Right-sided rhabdoid colorectal tumors might be related to the serrated pathway.
Author: Pancione, Massimo|Remo, Andrea|Sabatino, Lina|Zanella, Caterina|Votino, Carolina|Fucci, Alessandra|Di Blasi, Arturo|Lepore, Giovanni|Daniele, Bruno|Fenizia, Francesca|Molinari, Enrico|Normanno, Nicola|Manfrin, Erminia|Vendraminelli, Roberto|Colantuoni, Vi
PMID: 23425390
Journal: Am J Surg Pathol. 2013 Apr;37(4):579-85.
Title: Histologic evaluation of prophylactic hysterectomy and oophorectomy in Lynch syndrome.
Author: Karamurzin, Yevgeniy|Soslow, Robert A|Garg, Karuna
PMID: 23426126
Journal: Eur J Cancer. 2013 May;49(7):1578-87.
Title: Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?
Author: Win, Aung Ko|Hopper, John L|Buchanan, Daniel D|Young, Joanne P|Tenesa, Albert|Dowty, James G|Giles, Graham G|Goldblatt, Jack|Winship, Ingrid|Boussioutas, Alex|Young, Graeme P|Parry, Susan|Baron, John A|Duggan, David|Gallinger, Steven|Newcomb, Polly A|Hail
PMID: 23434150
Journal: S Afr J Surg. 2013 Feb 14;51(1):16-21.
Title: Mismatch repair deficiency in colorectal cancer patients in a low-incidence area.
Author: Vergouwe, F|Boutall, A|Stupart, D|Algar, U|Govender, D|van der Linde, G D|Mall, A|Ramesar, R|Goldberg, P A
PMID: 23472647
Journal: Biomed Res Int. 2013;2013:219897.
Title: Contribution of large genomic rearrangements in Italian Lynch syndrome patients: characterization of a novel alu-mediated deletion.
Author: Duraturo, Francesca|Cavallo, Angela|Liccardo, Raffaella|Cudia, Bianca|De Rosa, Marina|Diana, Giuseppe|Izzo, Paola
PMID: 23484096
Journal: Fam Cancer. 2013 Jun;12(2):295-300.
Title: Surgical treatment of hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome).
Author: Rodriguez-Bigas, Miguel A|Moeslein, Gabriela
PMID: 23508345
Journal: Am J Clin Pathol. 2013 Apr;139(4):434-41.
Title: Objective criteria for crohn-like lymphoid reaction in colorectal cancer.
Author: Ueno, Hideki|Hashiguchi, Yojiro|Shimazaki, Hideyuki|Shinto, Eiji|Kajiwara, Yoshiki|Nakanishi, Kuniaki|Kato, Kei|Maekawa, Kazuya|Miyai, Kosuke|Nakamura, Takahiro|Yamamoto, Junji|Hase, Kazuo
PMID: 23525613
Journal: PLoS One. 2013;8(3):e51240.
Title: Prevalence of pathological germline mutations of hMLH1 and hMSH2 genes in colorectal cancer.
Author: Li, Dandan|Hu, Fulan|Wang, Fan|Cui, Binbin|Dong, Xinshu|Zhang, Wencui|Lin, Chunqing|Li, Xia|Wang, Da|Zhao, Yashuang
PMID: 23526924
Journal: Int J Cancer. 2013 Oct 1;133(7):1762-3.
Title: Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid?
Author: Win, Aung Ko|Jenkins, Mark A
PMID: 23536426
Journal: Scand J Gastroenterol. 2013 Jun;48(6):672-8.
Title: Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.
Author: Tanskanen, Tomas|Gylfe, Alexandra E|Katainen, Riku|Taipale, Minna|Renkonen-Sinisalo, Laura|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Tuupanen, Sari|Kilpivaara, Outi|Vahteristo, Pia|Aaltonen, Lauri A
PMID: 23544471
Journal: Int J Cancer. 2013 Oct 1;133(7):1624-30.
Title: BRAF V600E-specific immunohistochemistry for the exclusion of Lynch syndrome in MSI-H colorectal cancer.
Author: Capper, David|Voigt, Anita|Bozukova, Gergana|Ahadova, Aysel|Kickingereder, Philipp|von Deimling, Andreas|von Knebel Doeberitz, Magnus|Kloor, Matthias
PMID: 23553055
Journal: PLoS One. 2013;8(3):e59064.
Title: MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular features.
Author: Li, Xia|Yao, Xiaoping|Wang, Yibaina|Hu, Fulan|Wang, Fan|Jiang, Liying|Liu, Yupeng|Wang, Da|Sun, Guizhi|Zhao, Yashuang
PMID: 23555617
Journal: Pediatr Hematol Oncol. 2013 May;30(4):273-84.
Title: Tissue expression of MLH1, PMS2, MSH2, and MSH6 proteins and prognostic value of microsatellite instability in Wilms tumor: experience of 45 cases.
Author: Diniz, Gulden|Aktas, Safiye|Cubuk, Cankut|Ortac, Ragip|Vergin, Canan|Olgun, Nur
PMID: 23570624
Journal: PLoS One. 2013;8(4):e60233.
Title: Novel DNA variants and mutation frequencies of hMLH1 and hMSH2 genes in colorectal cancer in the Northeast China population.
Author: Hu, Fulan|Li, Dandan|Wang, Yibaina|Yao, Xiaoping|Zhang, Wencui|Liang, Jing|Lin, Chunqing|Ren, Jiaojiao|Zhu, Lin|Wu, Zhiwei|Li, Shuying|Li, Ye|Zhao, Xiaojuan|Cui, Binbin|Dong, Xinshu|Tian, Suli|Zhao, Yashuang
PMID: 23573243
Journal: Gene. 2013 Jul 10;523(2):199-204.
Title: The hMLH1 promoter polymorphisms and cancer susceptibility in Asian populations: a meta-analysis.
Author: He, Yuanzhou|Xu, Xiangqin|Chen, Huilong|Wang, Jianmiao|Xiong, Weining|Xu, Yongjian|Liu, Jin
PMID: 23587910
Journal: Clin Adv Hematol Oncol. 2013 Apr;11(4):234-6.
Title: The BRAF mutation in MLH1-deficient colorectal cancer.
Author: Mahesh, Sameer A
PMID: 23604240
Journal: Asian Pac J Cancer Prev. 2013;14(2):619-24.
Title: Contribution of the MLH1 -93G>a promoter polymorphism in modulating susceptibility risk in Malaysian colorectal cancer patients.
Author: Nizam, Zahary Mohd|Abdul Aziz, Ahmad Aizat|Kaur, Gurjeet|Abu Hassan, Muhammad Radzi|Mohd Sidek, Ahmad Shanwani|Yeh, Lee Yeong|Mazuwin, Maya|Ankathil, Ravindran
PMID: 23621208
Journal: Cancer Chemother Pharmacol. 2013 Jul;72(1):117-25.
Title: MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.
Author: Tentori, Lucio|Muzi, Alessia|Dorio, Annalisa Susanna|Dolci, Susanna|Campolo, Federica|Vernole, Patrizia|Lacal, Pedro Miguel|Praz, Francoise|Graziani, Grazia
PMID: 23636450
Journal: Cell Oncol (Dordr). 2013 Jun;36(3):225-31.
Title: Mismatch repair gene mutation analysis and colonoscopy surveillance in Chinese Lynch syndrome families.
Author: Fu, Lei|Sheng, Jian-qiu|Li, Xiao-ou|Jin, Peng|Mu, Hong|Han, Min|Huang, Ji-sheng|Sun, Zi-qin|Li, Ai-qin|Wu, Zi-tao|Li, Shi-rong
PMID: 23640085
Journal: Mutat Res. 2013 Jul-Aug;747-748:19-27.
Title: Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.
Author: Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Carethers, John M
PMID: 23643670
Journal: Am J Surg Pathol. 2013 Aug;37(8):1192-200.
Title: High-level microsatellite instability in appendiceal carcinomas.
Author: Taggart, Melissa W|Galbincea, John|Mansfield, Paul F|Fournier, Keith F|Royal, Richard E|Overman, Michael J|Rashid, Asif|Abraham, Susan C
PMID: 23648460
Journal: Genes Chromosomes Cancer. 2013 Aug;52(8):748-52.
Title: BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma.
Author: Affolter, Kajsa|Samowitz, Wade|Tripp, Sheryl|Bronner, Mary P
PMID: 23650027
Journal: Int J Oncol. 2013 Jul;43(1):210-8.
Title: Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.
Author: Tentori, Lucio|Leonetti, Carlo|Muzi, Alessia|Dorio, Annalisa Susanna|Porru, Manuela|Dolci, Susanna|Campolo, Federica|Vernole, Patrizia|Lacal, Pedro Miguel|Praz, Francoise|Graziani, Grazia
PMID: 23653048
Journal: PLoS One. 2013 May 28;8(5):e65369.
Title: MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
Author: Park, Jae Myung|Huang, Shengbing|Tougeron, David|Sinicrope, Frank A
PMID: 23724141
Journal: Acta Biochim Pol. 2013;60(2):195-8. Epub 2013 Jun 6.
Title: Development of a new, simple and cost-effective diagnostic tool for genetic screening of hereditary colorectal cancer--the DNA microarray assay.
Author: Stojcev, Zoran|Banasiewicz, Tomasz|Kaszuba, Michal|Sikorski, Adam|Szczepkowski, Marek|Bobkiewicz, Adam|Paszkowski, Jacek|Krokowicz, Lukasz|Biczysko, Maciej|Szmeja, Jacek|Jurkowska, Monika|Majewski, Przemyslaw|Mackiewicz, Andrzej|Lamperska, Katarzyna|Drews
PMID: 23741719
Journal: Urol Oncol. 2013 Jul;31(5):716.
Title: Commentary on "Risks of primary extracolonic cancers following colorectal cancer in Lynch syndrome." Win AK, Lindor NM, Young JP, Macrae FA, Young GP, Williamson E, Parry S, Goldblatt J, Lipton L, Winship I, Leggett B, Tucker KM, Giles GG, Buchanan DD, Cl
Author: See, William A
PMID: 23796201
Journal: Am J Surg Pathol. 2013 Oct;37(10):1592-602.
Title: BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome.
Author: Toon, Christopher W|Walsh, Michael D|Chou, Angela|Capper, David|Clarkson, Adele|Sioson, Loretta|Clarke, Stephen|Mead, Scott|Walters, Rhiannon J|Clendenning, Mark|Rosty, Christophe|Young, Joanne P|Win, Aung Ko|Hopper, John L|Crook, Ashley|von Deimling, And
PMID: 23797718
Journal: Mod Pathol. 2013 Dec;26(12):1642-56.
Title: Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.
Author: Walsh, Michael D|Clendenning, Mark|Williamson, Elizabeth|Pearson, Sally-Ann|Walters, Rhiannon J|Nagler, Belinda|Packenas, David|Win, Aung K|Hopper, John L|Jenkins, Mark A|Haydon, Andrew M|Rosty, Christophe|English, Dallas R|Giles, Graham G|McGuckin, Micha
PMID: 23807779
Journal: Malays J Pathol. 2013 Jun;35(1):45-57.
Title: Pattern of hMLH1, hMSH2 and hMSH6 expression and clinical characteristics in a sample of Malaysian colorectal carcinoma cases.
Author: Khoo, J J|Gunn, A|Peh, S C
PMID: 23817394
Journal: World J Gastroenterol. 2013 Jul 7;19(25):3957-68.
Title: Differential mucin phenotypes and their significance in a variation of colorectal carcinoma.
Author: Imai, Yasuo|Yamagishi, Hidetsugu|Fukuda, Kazunori|Ono, Yuko|Inoue, Tohru|Ueda, Yoshihiko
PMID: 23840140
Journal: Int J Colorectal Dis. 2013 Dec;28(12):1643-9.
Title: Quality colonoscopy and risk of interval cancer in Lynch syndrome.
Author: Haanstra, J F|Vasen, H F A|Sanduleanu, S|van der Wouden, E J|Koornstra, J J|Kleibeuker, J H|de Vos Tot Nederveen Cappel, W H
PMID: 23857598
Journal: J Natl Cancer Inst. 2013 Aug 7;105(15):1151-6.
Title: Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.
Author: Lochhead, Paul|Kuchiba, Aya|Imamura, Yu|Liao, Xiaoyun|Yamauchi, Mai|Nishihara, Reiko|Qian, Zhi Rong|Morikawa, Teppei|Shen, Jeanne|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 23878352
Journal: Am J Surg Pathol. 2013 Nov;37(11):1660-70.
Title: Clinicopathologic features of synchronous colorectal carcinoma: A distinct subset arising from multiple sessile serrated adenomas and associated with high levels of microsatellite instability and favorable prognosis.
Author: Hu, Huankai|Chang, Daniel T|Nikiforova, Marina N|Kuan, Shih-Fan|Pai, Reetesh K
PMID: 23887157
Journal: World J Surg. 2013 Oct;37(10):2468-75.
Title: Mismatch repair deficiency screening via immunohistochemical staining in young Asians with colorectal cancers.
Author: Chew, Min-Hoe|Koh, Poh-Koon|Tan, Melinda|Lim, Kiat-Hon|Carol, Loi|Tang, Choong-Leong
PMID: 23887594
Journal: Am J Clin Pathol. 2013 Aug;140(2):177-83.
Title: BRAF V600E mutation analysis simplifies the testing algorithm for Lynch syndrome.
Author: Jin, Ming|Hampel, Heather|Zhou, Xiaoping|Schunemann, Lisa|Yearsley, Martha|Frankel, Wendy L
PMID: 23897252
Journal: Biomark Med. 2013 Aug;7(4):613-21.
Title: Microsatellite instability affecting the T17 repeats in intron 8 of HSP110, as well as five mononucleotide repeats in patients with colorectal carcinoma.
Author: Markovic, Srdjan|Antic, Jadranka|Dimitrijevic, Ivan|Zogovic, Branimir|Bojic, Daniela|Svorcan, Petar|Markovic, Velimir|Krivokapic, Zoran
PMID: 23905898
Journal: Hered Cancer Clin Pract. 2013 Aug 12;11(1):9.
Title: Germline deletions in the EPCAM gene as a cause of Lynch syndrome - literature review.
Author: Tutlewska, Katarzyna|Lubinski, Jan|Kurzawski, Grzegorz
PMID: 23938213
Journal: Virchows Arch. 2013 Nov;463(5):613-21.
Title: BRAF mutation in sporadic colorectal cancer and Lynch syndrome.
Author: Thiel, Alexandra|Heinonen, Mira|Kantonen, Jonas|Gylling, Annette|Lahtinen, Laura|Korhonen, Mari|Kytola, Soili|Mecklin, Jukka-Pekka|Orpana, Arto|Peltomaki, Paivi|Ristimaki, Ari
PMID: 23963522
Journal: World J Gastroenterol. 2013 Aug 28;19(32):5286-94.
Title: Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.
Author: Aissi, Sana|Buisine, Marie Pierre|Zerimech, Farid|Kourda, Nadia|Moussa, Amel|Manai, Mohamed|Porchet, Nicole
PMID: 23983431
Journal: Am J Surg Pathol. 2013 Oct;37(10):1532-41.
Title: Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal cancer.
Author: Kim, Jung Ho|Rhee, Ye-Young|Bae, Jeong Mo|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 24025523
Journal: Cell Oncol (Dordr). 2013 Oct;36(5):411-9.
Title: Regulation of MLH1 mRNA and protein expression by promoter methylation in primary colorectal cancer: a descriptive and prognostic cancer marker study.
Author: Jensen, Lars Henrik|Rasmussen, Anders Aamann|Byriel, Lene|Kuramochi, Hidekazu|Cruger, Dorthe Gylling|Lindebjerg, Jan|Danenberg, Peter V|Jakobsen, Anders|Danenberg, Kathleen
PMID: 24027018
Journal: Hum Pathol. 2013 Nov;44(11):2518-28.
Title: Lynch syndrome-associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach.
Author: Hartman, Douglas J|Brand, Randall E|Hu, Huankai|Bahary, Nathan|Dudley, Beth|Chiosea, Simon I|Nikiforova, Marina N|Pai, Reetesh K
PMID: 24034859
Journal: PLoS Curr. 2013 Sep 16;5.
Title: Genetic testing strategies in newly diagnosed endometrial cancer patients aimed at reducing morbidity or mortality from lynch syndrome in the index case or her relatives.
Author: Stewart, Alison Phd
PMID: 24056992
Journal: Mol Biol Rep. 2013 Oct;40(10):5921-9.
Title: Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
Author: Polakova Vymetalkova, Veronika|Vannucci, Luca|Korenkova, Vlasta|Prochazka, Pavel|Slyskova, Jana|Vodickova, Ludmila|Rusnakova, Vendula|Bielik, Ludovit|Burocziova, Monika|Rossmann, Pavel|Vodicka, Pavel
PMID: 24065530
Journal: BMC Med Genet. 2013 Oct 3;14:103.
Title: Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients.
Author: Petersen, Sanne M|Dandanell, Mette|Rasmussen, Lene J|Gerdes, Anne-Marie|Krogh, Lotte N|Bernstein, Inge|Okkels, Henrik|Wikman, Friedrik|Nielsen, Finn C|Hansen, Thomas V O
PMID: 24090359
Journal: Oncol Rep. 2013 Dec;30(6):2909-16.
Title: Molecular and clinical characteristics of MSH6 germline variants detected in colorectal cancer patients.
Author: Terui, Hiroko|Tachikawa, Tetsuhiko|Kakuta, Miho|Nishimura, Yoji|Yatsuoka, Toshimasa|Yamaguchi, Kensei|Yura, Kei|Akagi, Kiwamu
PMID: 24100870
Journal: Am J Clin Nutr. 2013 Dec;98(6):1564-74.
Title: The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.
Author: Hanks, Joanna|Ayed, Iyeman|Kukreja, Neil|Rogers, Chris|Harris, Jessica|Gheorghiu, Alina|Liu, Chee Ling|Emery, Peter|Pufulete, Maria
PMID: 24108782
Journal: J Surg Oncol. 2013 Dec;108(7):433-7.
Title: Excess of extracolonic non-endometrial multiple primary cancers in MSH2 germline mutation carriers over MLH1.
Author: Lin-Hurtubise, Kevin M|Yheulon, Christopher G|Gagliano, Ronald A Jr|Lynch, Henry T
PMID: 24122742
Journal: Front Oncol. 2013 Oct 11;3:265.
Title: Loss of Cdx2 Expression in Primary Tumors and Lymph Node Metastases is Specific for Mismatch Repair-Deficiency in Colorectal Cancer.
Author: Dawson, Heather|Koelzer, Viktor H|Lukesch, Anne C|Mallaev, Makhmudbek|Inderbitzin, Daniel|Lugli, Alessandro|Zlobec, Inti
PMID: 24130965
Journal: Transl Oncol. 2013 Oct 1;6(5):520-7. eCollection 2013.
Title: Ephrin b2 receptor and microsatellite status in lymph node-positive colon cancer survival.
Author: Drucker, Arik|Arnason, Thomas|Yan, Sen Rong|Aljawad, Mohammed|Thompson, Kara|Huang, Weei-Yuarn
PMID: 24151532
Journal: N Z Med J. 2013 Sep 13;126(1382):70-7.
Title: Immunochemistry screening for Lynch syndrome in colorectal adenocarcinoma using an initial two antibody panel can replace a four antibody panel.
Author: O'Regan, Toni|Chau, Kai|Tatton, Michael|Smith, Tania|Parry, Susan|Bissett, Ian
PMID: 24154771
Journal: Oncol Lett. 2013 Nov;6(5):1370-1376.
Title: Correlation of MLH1 and MGMT methylation levels between peripheral blood leukocytes and colorectal tissue DNA samples in colorectal cancer patients.
Author: Li, Xia|Wang, Yibaina|Zhang, Zuoming|Yao, Xiaoping|Ge, Jie|Zhao, Yashuang
PMID: 24179526
Journal: Oncol Lett. 2013 Nov;6(5):1413-1420.
Title: Microsatellite instability and loss of heterozygosity detected in middle-aged patients with sporadic colon cancer: A retrospective study.
Author: Kamat, Nasir|Khidhir, Mohammed A|Alashari, Mouied M|Rannug, Ulf
PMID: 24179534
Journal: PLoS Genet. 2013 Oct;9(10):e1003869.
Title: Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway.
Author: Smith, Catherine E|Mendillo, Marc L|Bowen, Nikki|Hombauer, Hans|Campbell, Christopher S|Desai, Arshad|Putnam, Christopher D|Kolodner, Richard D
PMID: 24204293
Journal: PLoS One. 2013 Oct 8;8(10):e76865.
Title: Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice.
Author: Pussila, Marjaana|Sarantaus, Laura|Dermadi Bebek, Denis|Valo, Satu|Reyhani, Nima|Ollila, Saara|Paivarinta, Essi|Peltomaki, Paivi|Mutanen, Marja|Nystrom, Minna
PMID: 24204690
Journal: Oncol Lett. 2013 Dec;6(6):1687-1692.
Title: DNA methylation as an epigenetic biomarker in colorectal cancer.
Author: Silva, Tiago Donizetti|Vidigal, Veronica Marques|Felipe, Aledson Vitor|DE Lima, Jacqueline Miranda|Neto, Ricardo Artigiani|Saad, Sarhan Sidney|Forones, Nora Manoukian
PMID: 24260063
Journal: Asian Pac J Cancer Prev. 2013;14(10):5609-14.
Title: Genes and SNPs associated with non-hereditary and hereditary colorectal cancer.
Author: Nassiri, Mohammadreza|Kooshyar, Mohammad Mahdi|Roudbar, Zahra|Mahdavi, Morteza|Doosti, Mohammad
PMID: 24289550
Journal: J Gastrointest Oncol. 2013 Dec;4(4):397-408.
Title: Mismatch repair protein expression in colorectal cancer.
Author: Kheirelseid, Elrasheid A H|Miller, Nicola|Chang, Kah Hoong|Curran, Catherine|Hennessey, Emer|Sheehan, Margaret|Kerin, Michael J
PMID: 24294512
Journal: Genet Mol Res. 2013 Dec 4;12(4):6268-74.
Title: Colorectal cancer susceptibility variants alter risk of breast cancer in a Chinese Han population.
Author: Wei, W|Jiang, M|Luo, L|Li, Z|Wang, P|Dong, W Q
PMID: 24338422
Journal: Indian J Surg. 2013 Jun;75(Suppl 1):456-9.
Title: Synchronous rectal and gastric cancer in a fighter pilot: aeromedical concerns.
Author: Gu, Guo-Li|Wei, Xue-Ming|Xu, Xian-Rong|Li, De-Chang|Wang, Shi-Lin|Gu, Jin
PMID: 24426647
Journal: Acta Med Indones. 2013 Oct;45(4):275-83.
Title: Adenomatous Polyposis Coli, mismatch repair, and microsatellite instability in colorectal cancer based on different locations.
Author: Effendi-Y S, Rustam|Zain, Lukman H|Siregar, Gontar A|Lubis, Harun R|Damanik, Harun A|Laksmi, Lidya I|Chrestella, Jessy
PMID: 24448331
Journal: Ann Coloproctol. 2013 Dec;29(6):252-5.
Title: Rhabdoid carcinoma of the rectum.
Author: Samalavicius, Narimantas Evaldas|Stulpinas, Rokas|Gasilionis, Valdas|Baltruskeviciene, Edita|Aleknavicius, Eduardas|Mickys, Ugnius
PMID: 24466541
Journal: Cancer Biomark. 2013 Jan 1;13(6):427-32.
Title: Molecular analysis of imperative polymorphisms of MLH1 gene in sporadic colorectal cancer.
Author: Milanizadeh, Saman|Khanyaghma, Mahsa|Haghighi, Mahdi Montazer|Mohebbi, Seyedreza|Damavand, Behzad|Almasi, Shohreh|Azimzadeh, Pedram|Zali, Mohammadreza
PMID: 24595079
Journal: Genes (Basel). 2013 Sep 26;4(4):536-55.
Title: Copy number variation in hereditary non-polyposis colorectal cancer.
Author: Masson, Amy L|Talseth-Palmer, Bente A|Evans, Tiffany-Jane|Grice, Desma M|Duesing, Konsta|Hannan, Garry N|Scott, Rodney J
PMID: 24705261
Journal: Gastroenterol Rep (Oxf). 2013 Jul;1(1):70-4.
Title: BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer.
Author: Lee, Seung-Hyun|Ahn, Byung-Kwon|Baek, Sung-Uhn|Chang, Hee-Kyung
PMID: 24759670
Journal: Chin Clin Oncol. 2013 Jun;2(2):12.
Title: Practical genetics of colorectal cancer.
Author: Lynch, Henry T|Shaw, Trudy G
PMID: 25841492
Journal: Clin J Gastroenterol. 2013 Apr;6(2):122-6.
Title: Gastric cancers with microsatellite instability sharing clinical features, chemoresistance and germline MSH6 variants.
Author: Yamashita, Kentaro|Arimura, Yoshiaki|Saito, Mayuko|Suzuki, Hiromu|Furuhata, Tomohisa|Hirata, Koichi|Shinomura, Yasuhisa
PMID: 26181448
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E1-10.
Title: Differential expression of CD133 based on microsatellite instability status in human colorectal cancer.
Author: Park, Jae Jun|Kwon, Ji-hee|Oh, Sun-Hee|Choi, Junjeong|Moon, Chang Mo|Ahn, Joong Bae|Hong, Sung Pil|Cheon, Jae Hee|Kim, Tae Il|Kim, Hoguen|Kim, Won Ho
PMID: 23065858
Journal: Fam Cancer. 2014 Mar;13(1):29-34.
Title: No evidence of genetic anticipation in a large family with Lynch syndrome.
Author: Stupart, D|Goldberg, P|Algar, U|Vorster, A|Ramesar, R
PMID: 23771324
Journal: Oncogene. 2014 Jun 5;33(23):2949-55.
Title: Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Author: Ogino, S|Lochhead, P|Giovannucci, E|Meyerhardt, J A|Fuchs, C S|Chan, A T
PMID: 23792451
Journal: Fam Cancer. 2014 Mar;13(1):1-12.
Title: Endometrial tumour BRAF mutations and MLH1 promoter methylation as predictors of germline mismatch repair gene mutation status: a literature review.
Author: Metcalf, Alexander M|Spurdle, Amanda B
PMID: 23880961
Journal: Clin Gastroenterol Hepatol. 2014 May;12(5):715-27; quiz e41-3.
Title: History, genetics, and strategies for cancer prevention in Lynch syndrome.
Author: Kastrinos, Fay|Stoffel, Elena M
PMID: 23891921
Journal: J Community Genet. 2014 Jan;5(1):31-48.
Title: Patient compliance based on genetic medicine: a literature review.
Author: Schneider, Kai Insa|Schmidtke, Jorg
PMID: 23934761
Journal: Gut. 2014 Feb;63(2):326-36.
Title: Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.
Author: Ma, Xiangyu|Zhang, Ben|Zheng, Wei
PMID: 23946381
Journal: J Pediatr Gastroenterol Nutr. 2014 Feb;58(2):144-52.
Title: Lynch syndrome: a pediatric perspective.
Author: Huang, Sherry C|Durno, Carol A|Erdman, Steven H
PMID: 24051481
Journal: Fam Cancer. 2014 Mar;13(1):109-19.
Title: Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer.
Author: Garre, Pilar|Martin, Lorena|Bando, Inmaculada|Tosar, Alicia|Llovet, Patricia|Sanz, Julian|Romero, Atocha|de la Hoya, Miguel|Diaz-Rubio, Eduardo|Caldes, Trinidad
PMID: 24061861
Journal: Mod Pathol. 2014 May;27(5):644-50.
Title: BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer.
Author: Toon, Christopher W|Chou, Angela|DeSilva, Keshani|Chan, Joseph|Patterson, Jillian|Clarkson, Adele|Sioson, Loretta|Jankova, Lucy|Gill, Anthony J
PMID: 24157612
Journal: Int J Cancer. 2014 May 15;134(10):2342-51.
Title: Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
Author: Dawson, Heather|Galvan, Jose A|Helbling, Melina|Muller, Dominique-Elisabeth|Karamitopoulou, Eva|Koelzer, Viktor H|Economou, Mary|Hammer, Caroline|Lugli, Alessandro|Zlobec, Inti
PMID: 24166180
Journal: Pathol Res Pract. 2014 Feb;210(2):98-104.
Title: Clinicopathologic characteristics of colorectal cancer with microsatellite instability.
Author: Ziadi, S|Ksiaa, F|Ben Gacem, R|Labaied, N|Mokni, M|Trimeche, M
PMID: 24286815
Journal: Genet Med. 2014 Jan;16(1):101-16.
Title: ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis).
Author: Hegde, Madhuri|Ferber, Mathew|Mao, Rong|Samowitz, Wade|Ganguly, Arupa
PMID: 24310308
Journal: Tumour Biol. 2014 Apr;35(4):3679-87.
Title: Promoter methylation and immunohistochemical expression of hMLH1 and hMSH2 in sporadic colorectal cancer: a study from India.
Author: Malhotra, Pooja|Anwar, Mumtaz|Kochhar, Rakesh|Ahmad, Shabeer|Vaiphei, Kim|Mahmood, Safrun
PMID: 24317816
Journal: Pathol Res Pract. 2014 Feb;210(2):111-7.
Title: Role of topoisomerase I and thymidylate synthase expression in sporadic colorectal cancer: associations with clinicopathological and molecular features.
Author: Azzoni, Cinzia|Bottarelli, Lorena|Cecchini, Stefano|Ziccarelli, Antonio|Campanini, Nicoletta|Bordi, Cesare|Sarli, Leopoldo|Silini, Enrico Maria
PMID: 24332575
Journal: Gynecol Oncol. 2014 Feb;132(2):506-12.
Title: Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications.
Author: Xiao, Xue|Melton, David W|Gourley, Charlie
PMID: 24333356
Journal: Cancer Res. 2014 Mar 1;74(5):1311-8.
Title: Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
Author: Tahara, Tomomitsu|Yamamoto, Eiichiro|Suzuki, Hiromu|Maruyama, Reo|Chung, Woonbok|Garriga, Judith|Jelinek, Jaroslav|Yamano, Hiro-o|Sugai, Tamotsu|An, Byonggu|Shureiqi, Imad|Toyota, Minoru|Kondo, Yutaka|Estecio, Marcos R H|Issa, Jean-Pierre J
PMID: 24385213
Journal: Tumour Biol. 2014 May;35(5):4347-55.
Title: Microsatellite instability and promoter hypermethylation in colorectal cancer in India.
Author: Kanth, V V Ravi|Bhalsing, Sandeep|Sasikala, M|Rao, G V|Pradeep, R|Avanthi, Urmila Steffie|Reddy, D Nageshwar
PMID: 24408015
Journal: World J Gastroenterol. 2014 Jan 7;20(1):250-7.
Title: Epithelial-mesenchymal transition in colorectal cancer tissue of patients with Lynch syndrome.
Author: Gu, Guo-Li|Zhu, Xiao-Quan|Wei, Xue-Ming|Ren, Li|Li, De-Chang|Wang, Shi-Lin
PMID: 24415879
Journal: Br J Cancer. 2014 Mar 4;110(5):1228-35.
Title: Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia.
Author: Malesci, A|Basso, G|Bianchi, P|Fini, L|Grizzi, F|Celesti, G|Di Caro, G|Delconte, G|Dattola, F|Repici, A|Roncalli, M|Montorsi, M|Laghi, L
PMID: 24434431
Journal: Arch Pathol Lab Med. 2014 Aug;138(8):1015-26.
Title: Cadherin-17 and SATB2 are sensitive and specific immunomarkers for medullary carcinoma of the large intestine.
Author: Lin, Fan|Shi, Jianhui|Zhu, Shaobo|Chen, Zongming|Li, Aihua|Chen, Taiying|Wang, Hanlin L|Liu, Haiyan
PMID: 24437456
Journal: Mol Cancer. 2014 Jan 24;13:11.
Title: Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1.
Author: Hinrichsen, Inga|Ernst, Benjamin Philipp|Nuber, Franziska|Passmann, Sandra|Schafer, Dieter|Steinke, Verena|Friedrichs, Nicolaus|Plotz, Guido|Zeuzem, Stefan|Brieger, Angela
PMID: 24456667
Journal: PLoS One. 2014 Jan 21;9(1):e86657.
Title: Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels.
Author: Berg, Marianne|Hagland, Hanne R|Soreide, Kjetil
PMID: 24466191
Journal: Int J Cancer. 2014 Sep 1;135(5):1085-91.
Title: Population-based screening for Lynch syndrome in Western Australia.
Author: Schofield, Lyn|Grieu, Fabienne|Amanuel, Benhur|Carrello, Amerigo|Spagnolo, Dominic|Kiraly, Cathy|Pachter, Nicholas|Goldblatt, Jack|Platell, Cameron|Levitt, Michael|Stewart, Colin|Salama, Paul|Ee, Hooi|Raftopoulous, Spiro|Katris, Paul|Threlfall, Tim|Edkins
PMID: 24474394
Journal: PLoS One. 2014 Jan 27;9(1):e82185.
Title: An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Author: Brim, Hassan|Abu-Asab, Mones S|Nouraie, Mehdi|Salazar, Jose|Deleo, Jim|Razjouyan, Hadi|Mokarram, Pooneh|Schaffer, Alejandro A|Naghibhossaini, Fakhraddin|Ashktorab, Hassan
PMID: 24475022
Journal: BMC Med Genet. 2014 Jan 31;15:17.
Title: Molecular characteristics of mismatch repair genes in sporadic colorectal tumors in Czech patients.
Author: Vymetalkova, Veronika Polakova|Slyskova, Jana|Korenkova, Vlasta|Bielik, Ludovit|Langerova, Lucie|Prochazka, Pavel|Rejhova, Alexandra|Schwarzova, Lucie|Pardini, Barbara|Naccarati, Alessio|Vodicka, Pavel
PMID: 24484585
Journal: Int J Cancer. 2014 Jul 1;135(1):69-77.
Title: Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: a comprehensive analysis of 3,671 families.
Author: Steinke, Verena|Holzapfel, Stefanie|Loeffler, Markus|Holinski-Feder, Elke|Morak, Monika|Schackert, Hans K|Gorgens, Heike|Pox, Christian|Royer-Pokora, Brigitte|von Knebel-Doeberitz, Magnus|Buttner, Reinhard|Propping, Peter|Engel, Christoph
PMID: 24493211
Journal: Genet Test Mol Biomarkers. 2014 Apr;18(4):236-44.
Title: Telomere shortening: a biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins.
Author: Haghighi, Mahdi Montazer|Aghagolzadeh, Parisa|Zadeh, Saman Milani|Molaei, Mahsa|Zali, Mohammad Reza|Radpour, Ramin
PMID: 24495131
Journal: Epigenetics. 2014 Apr;9(4):621-33.
Title: Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
Author: Coppede, Fabio|Migheli, Francesca|Lopomo, Angela|Failli, Alessandra|Legitimo, Annalisa|Consolini, Rita|Fontanini, Gabriella|Sensi, Elisa|Servadio, Adele|Seccia, Massimo|Zocco, Giuseppe|Chiarugi, Massimo|Spisni, Roberto|Migliore, Lucia
PMID: 24500500
Journal: Am J Surg Pathol. 2014 Jul;38(7):910-20.
Title: SMARCB1 (INI1)-negative rhabdoid carcinomas of the gastrointestinal tract: clinicopathologic and molecular study of a highly aggressive variant with literature review.
Author: Agaimy, Abbas|Rau, Tilman T|Hartmann, Arndt|Stoehr, Robert
PMID: 24503755
Journal: Am J Surg Pathol. 2014 Jun;38(6):793-800.
Title: Association of tumor morphology with mismatch-repair protein status in older endometrial cancer patients: implications for universal versus selective screening strategies for Lynch syndrome.
Author: Rabban, Joseph T|Calkins, Sarah M|Karnezis, Anthony N|Grenert, James P|Blanco, Amie|Crawford, Beth|Chen, Lee-May
PMID: 24503759
Journal: Epigenetics. 2014 May;9(5):738-46.
Title: CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.
Author: Sun, Lifeng|Guzzetta, Angela A|Fu, Tao|Chen, Jinming|Jeschke, Jana|Kwak, Ruby|Vatapalli, Rajita|Baylin, Stephen B|Iacobuzio-Donahue, Christine A|Wolfgang, Christopher L|Ahuja, Nita
PMID: 24518818
Journal: Hum Pathol. 2014 Mar;45(3):464-72.
Title: Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization.
Author: Kuan, Shih-Fan|Navina, Sarah|Cressman, Kristi L|Pai, Reetesh K
PMID: 24529329
Journal: BMC Surg. 2014 Feb 17;14:9.
Title: Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old.
Author: Baiocchi, Gian Luca|Portolani, Nazario|Vermi, William|Baronchelli, Carla|Gheza, Federico|Zogno, Claudio|Scaglia, Alessandro|Marchina, Eleonora|Tiberio, Guido A M|Giulini, Stefano Maria
PMID: 24533633
Journal: J Med Genet. 2014 May;51(5):283-93.
Title: Guidelines for surveillance of individuals with constitutional mismatch repair-deficiency proposed by the European Consortium "Care for CMMR-D" (C4CMMR-D).
Author: Vasen, H F A|Ghorbanoghli, Z|Bourdeaut, F|Cabaret, O|Caron, O|Duval, A|Entz-Werle, N|Goldberg, Y|Ilencikova, D|Kratz, C P|Lavoine, N|Loeffen, J|Menko, F H|Muleris, M|Sebille, G|Colas, C|Burkhardt, B|Brugieres, L|Wimmer, K
PMID: 24556086
Journal: PLoS One. 2014 Mar 3;9(3):e90607.
Title: BRAFV600E mutation and its association with clinicopathological features of colorectal cancer: a systematic review and meta-analysis.
Author: Chen, Dong|Huang, Jun-Fu|Liu, Kai|Zhang, Li-Qun|Yang, Zhao|Chuai, Zheng-Ran|Wang, Yun-Xia|Shi, Da-Chuan|Huang, Qing|Fu, Wei-Ling
PMID: 24594804
Journal: Nihon Rinsho. 2014 Jan;72(1):143-9.
Title: [Diagnosis and management of hereditary colorectal cancer according to the JSCCR Guidelines 2012 for the Clinical Practice of Hereditary Colorectal Cancer].
Author: Ishida, Hideyuki|Iwama, Takeo|Tomita, Naohiro|Koizumi, Kouichi|Akagi, Kiwamu|Ishiguro, Megumi|Watanabe, Toshiaki|Sugihara, Kenichi
PMID: 24597363
Journal: J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9.
Title: Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Author: Morimoto, Takashi|Mitomi, Hiroyuki|Saito, Tsuyoshi|Takahashi, Michiko|Murakami, Takashi|Sakamoto, Naoto|Yao, Takashi|Watanabe, Sumio
PMID: 24612059
Journal: Ann Transplant. 2014 Mar 7;19:124-8.
Title: Determining eligibility for and preparation to kidney transplantation of a patient with Lynch syndrome--a case report and literature review.
Author: Gozdowska, Jolanta|Bieniasz, Monika|Wszola, Michal|Kieszek, Rafal|Domagala, Piotr|Drozdowski, Jakub|Tomaszek, Aleksandra|Kwiatkowski, Artur|Chmura, Andrzej|Durlik, Magdalena
PMID: 24614524
Journal: Cesk Patol. 2014 Jan;50(1):18-24.
Title: [Lynch syndrome in the hands of pathologists].
Author: Daum, Ondrej|Benes, Zdenek|Hadravsky, Ladislav|Stehlik, Jan|Cerna, Katerina|Dusek, Martin|Kokoskova, Bohuslava|Michal, Michal
PMID: 24624982
Journal: Am J Surg Pathol. 2014 Apr;38(4):518-25.
Title: Immunohistochemistry for annexin A10 can distinguish sporadic from Lynch syndrome-associated microsatellite-unstable colorectal carcinoma.
Author: Pai, Reetesh K|Shadrach, Bonnie L|Carver, Paula|Heald, Brandie|Moline, Jessica|Church, James|Kalady, Matthew F|Burke, Carol A|Plesec, Thomas P|Lai, Keith K|Gonzalo, David H|Pai, Rish K
PMID: 24625416
Journal: Oncogenesis. 2014 Mar 17;3:e94.
Title: Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation.
Author: Kuga, T|Nie, H|Kazami, T|Satoh, M|Matsushita, K|Nomura, F|Maeshima, K|Nakayama, Y|Tomonaga, T
PMID: 24637494
Journal: Tumour Biol. 2014 Jul;35(7):6283-91.
Title: Immunohistochemical expression pattern of MMR protein can specifically identify patients with colorectal cancer microsatellite instability.
Author: Amira, Arfaoui Toumi|Mouna, Trabelsi|Ahlem, Blel|Raoudha, Aloui|Majid, Ben Hmida|Amel, Hamza|Rachida, Zermani|Nadia, Kourdaa
PMID: 24643686
Journal: Mol Genet Genomic Med. 2014 Mar;2(2):186-200.
Title: A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes.
Author: Hansen, Maren F|Neckmann, Ulrike|Lavik, Liss A S|Vold, Trine|Gilde, Bodil|Toft, Ragnhild K|Sjursen, Wenche
PMID: 24689082
Journal: Dig Dis Sci. 2014 Sep;59(9):2255-63.
Title: Genetic mechanisms in interval colon cancers.
Author: Richter, James M|Pino, Maria Simona|Austin, Thomas R|Campbell, Emily|Szymonifka, Jackie|Russo, Andrea L|Hong, Theodore S|Borger, Darrell|Iafrate, A John|Chung, Daniel C
PMID: 24705641
Journal: Neuro Oncol. 2014 Oct;16(10):1333-40.
Title: Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.
Author: Andersson, Ulrika|Wibom, Carl|Cederquist, Kristina|Aradottir, Steina|Borg, Ake|Armstrong, Georgina N|Shete, Sanjay|Lau, Ching C|Bainbridge, Matthew N|Claus, Elizabeth B|Barnholtz-Sloan, Jill|Lai, Rose|Il'yasova, Dora|Houlston, Richard S|Schildkraut, Joell
PMID: 24723567
Journal: PLoS One. 2014 Apr 17;9(4):e95022.
Title: The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.
Author: Abuli, Anna|Bujanda, Luis|Munoz, Jenifer|Buch, Stephan|Schafmayer, Clemens|Valeria Maiorana, Maria|Veneroni, Silvia|van Wezel, Tom|Liu, Tao|Westers, Helga|Esteban-Jurado, Clara|Ocana, Teresa|Pique, Josep M|Andreu, Montserrat|Jover, Rodrigo|Carracedo, Ange
PMID: 24743384
Journal: Int J Cancer. 2014 Dec 1;135(11):2507-15.
Title: MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.
Author: Ito, Miki|Mitsuhashi, Kei|Igarashi, Hisayoshi|Nosho, Katsuhiko|Naito, Takafumi|Yoshii, Shinji|Takahashi, Hiroaki|Fujita, Masahiro|Sukawa, Yasutaka|Yamamoto, Eiichiro|Takahashi, Taiga|Adachi, Yasushi|Nojima, Masanori|Sasaki, Yasushi|Tokino, Takashi|Baba, Y
PMID: 24752710
Journal: Med Oncol. 2014 Jun;31(6):975.
Title: The prognostic significance of polymorphisms in hMLH1/hMSH2 for colorectal cancer.
Author: Wang, Yibaina|Li, Guangxiao|Hu, Fulan|Bi, Haoran|Wu, Zhiwei|Zhao, Xiaojuan|Li, Ye|Li, Shuying|Li, Dandan|Cui, Binbin|Dong, Xinshu|Zhao, Yashuang
PMID: 24793746
Journal: Fam Cancer. 2014 Sep;13(3):401-13.
Title: A founder MLH1 mutation in Lynch syndrome families from Piedmont, Italy, is associated with an increased risk of pancreatic tumours and diverse immunohistochemical patterns.
Author: Borelli, Iolanda|Casalis Cavalchini, Guido C|Del Peschio, Serena|Micheletti, Monica|Venesio, Tiziana|Sarotto, Ivana|Allavena, Anna|Delsedime, Luisa|Barberis, Marco A|Mandrile, Giorgia|Berchialla, Paola|Ogliara, Paola|Bracco, Cecilia|Pasini, Barbara
PMID: 24802709
Journal: Asian Pac J Cancer Prev. 2014;15(7):3287-91.
Title: Colorectal carcinoma in Malaysians: DNA mismatch repair pattern in a multiethnic population.
Author: Cheah, Phaik-Leng|Looi, Lai-Meng|Teoh, Kean-Hooi|Rahman, Nazarina Abdul|Wong, Li-Xuan|Tan, Soo-Yong
PMID: 24815484
Journal: In Vivo. 2014 May-Jun;28(3):349-54.
Title: Cell-free DNA blood levels in colorectal cancer patients do not correlate with mismatch repair-proficiency.
Author: Lazarev, Irena|Leibovitch, Lital|Czeiger, David|Sion-Vardi, Neta|Geffen, David B|Douvdevani, Amos|Ariad, Samuel
PMID: 24815837
Journal: Gastroenterol Res Pract. 2014;2014:436985.
Title: Prognostic and predictive value of CpG island methylator phenotype in patients with locally advanced nonmetastatic sporadic colorectal cancer.
Author: Wang, Yuwei|Long, Yadong|Xu, Ye|Guan, Zuqing|Lian, Peng|Peng, Junjie|Cai, Sanjun|Cai, Guoxiang
PMID: 24822060
Journal: Nucleic Acids Res. 2014 Jun;42(11):7096-103.
Title: Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1.
Author: Bregenhorn, Stephanie|Jiricny, Josef
PMID: 24829445
Journal: Tumour Biol. 2014 Aug;35(8):8267-79.
Title: The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients.
Author: Yang, WenJie|Wang, XiaoFeng|Li, XiaoWei|Wang, Min|Chen, XiaoFeng|Wu, XiaoMei|Wang, YaPing|Fan, YiMei|Jin, HeiYing
PMID: 24852431
Journal: Acta Histochem. 2014 Jul;116(6):1007-14.
Title: Relationship of mismatch repair proteins and survivin in colon polyps and carcinomas.
Author: Adamkov, Marian|Furjelova, Martina|Horacek, Jaroslav|Bencat, Marian|Kruzliak, Peter
PMID: 24852932
Journal: Mol Med Rep. 2014 Aug;10(2):1003-6.
Title: The incidence of mismatch repair gene defects in colorectal liver metastases.
Author: Alvarado-Bachmann, Raul|Smith, Adrian|Gundara, Justin S|Kuo, Samuel C L|Gill, Anthony J|Samra, Jaswinder S|Hugh, Thomas J
PMID: 24859327
Journal: Can J Surg. 2014 Jun;57(3):199-208.
Title: Differences in telomerase activity between colon and rectal cancer.
Author: Ayiomamitis, Georgios D|Notas, George|Zaravinos, Apostolos|Zizi-Sermpetzoglou, Adamantia|Georgiadou, Maria|Sfakianaki, Ourania|Kouroumallis, Elias
PMID: 24869613
Journal: APMIS. 2014 Dec;122(12):1187-95.
Title: Annexin A10 expression correlates with serrated pathway features in colorectal carcinoma with microsatellite instability.
Author: Kim, Jung Ho|Rhee, Ye-Young|Kim, Kyung-Ju|Cho, Nam-Yun|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 24909058
Journal: Vopr Onkol. 2014;60(2):47-50.
Title: [Immunohistochemical examination of MSH2, PMS2, MLH1, MSH6 compared with the analysis of microsatellite instability in colon adenocarcinoma].
Author: Raskin, G A|Ianus, G A|Kornilov, A V|Orlova, R V|Petrov, S V|Protasova, A E|Pozharisskii, K M|Imianitov, E N
PMID: 24919261
Journal: Hum Mutat. 2014 Sep;35(9):1123-7.
Title: Assessing how reduced expression levels of the mismatch repair genes MLH1, MSH2, and MSH6 affect repair efficiency.
Author: Kansikas, Minttu|Kasela, Mariann|Kantelinen, Jukka|Nystrom, Minna
PMID: 24924810
Journal: Zhonghua Yi Xue Za Zhi. 2014 Apr 29;94(16):1261-4.
Title: [Effects of adenosine on hMLH1 methylation of human colorectal cancer cells].
Author: Xie, Kai|Wang, Yaxu|Shen, Haiying|Zhang, Lingmin|Zeng, Linghai|Shu, Ningbo|Li, Quan
PMID: 24924894
Journal: BMC Cancer. 2014 Jun 25;14:466.
Title: DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.
Author: Muto, Yuta|Maeda, Takafumi|Suzuki, Koichi|Kato, Takaharu|Watanabe, Fumiaki|Kamiyama, Hidenori|Saito, Masaaki|Koizumi, Kei|Miyaki, Yuichiro|Konishi, Fumio|Alonso, Sergio|Perucho, Manuel|Rikiyama, Toshiki
PMID: 24964857
Journal: Diagn Pathol. 2014 Jun 26;9:126.
Title: Heterogenous mismatch-repair status in colorectal cancer.
Author: Joost, Patrick|Veurink, Nynke|Holck, Susanne|Klarskov, Louise|Bojesen, Anders|Harbo, Maria|Baldetorp, Bo|Rambech, Eva|Nilbert, Mef
PMID: 24968821
Journal: Genes (Basel). 2014 Jun 27;5(3):497-507.
Title: Lynch syndrome: an updated review.
Author: Sehgal, Rishabh|Sheahan, Kieran|O'Connell, Patrick R|Hanly, Ann M|Martin, Sean T|Winter, Desmond C
PMID: 24978665
Journal: Med Oncol. 2014 Jul;31(7):39.
Title: Prognostic significance of hMLH1/hMSH2 gene mutations and hMLH1 promoter methylation in sporadic colorectal cancer.
Author: Wang, Yibaina|Li, Dandan|Li, Xia|Teng, Chong|Zhu, Lin|Cui, Binbin|Zhao, Yashuang|Hu, Fulan
PMID: 24990217
Journal: Mol Cancer. 2014 Jul 8;13:168.
Title: A very low incidence of BRAF mutations in Middle Eastern colorectal carcinoma.
Author: Siraj, Abdul K|Bu, Rong|Prabhakaran, Sarita|Bavi, Prashant|Beg, Shaham|Al Hazmi, Mohsen|Al-Rasheed, Maha|Alobaisi, Khadija|Al-Dayel, Fouad|AlManea, Hadeel|Al-Sanea, Nasser|Uddin, Shahab|Al-Kuraya, Khawla S
PMID: 25005754
Journal: Rev Gastroenterol Peru. 2014 Apr;34(2):107-14.
Title: [Inherited colorectal cancer predisposition syndromes identified in the Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru;].
Author: Castro-Mujica, Maria del Carmen|Sullcahuaman-Allende, Yasser|Barreda-Bolanos, Fernando|Taxa-Rojas, Luis
PMID: 25028899
Journal: Inflamm Bowel Dis. 2014 Sep;20(9):1584-92.
Title: Small bowel adenocarcinomas complicating Crohn's disease are associated with dysplasia: a pathological and molecular study.
Author: Svrcek, Magali|Piton, Gael|Cosnes, Jacques|Beaugerie, Laurent|Vermeire, Severine|Geboes, Karel|Lemoine, Antoinette|Cervera, Pascale|El-Murr, Nizar|Dumont, Sylvie|Scriva, Aurelie|Lascols, Olivier|Ardizzone, Sandro|Fociani, Paolo|Savoye, Guillaume|Le Pessot
PMID: 25029614
Journal: Vopr Onkol. 2014;60(3):313-8.
Title: [Simultaneous prophylactic surgery for colon cancer in women. Viewpoint of the gynecologist].
Author: PaIanidi, Iu G|Sel'chuk, V Iu|Zhordaniia, K I|Kazubskaia, T P|Kashurnikov, A Iu
PMID: 25033682
Journal: Cell Rep. 2014 Jul 24;8(2):501-13.
Title: Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.
Author: Lu, Yuhong|Wajapeyee, Narendra|Turker, Mitchell S|Glazer, Peter M
PMID: 25043185
Journal: Tumori. 2014 May-Jun;100(3):315-20.
Title: BRAF mutation analysis is a valid tool to implement in Lynch syndrome diagnosis in patients classified according to the Bethesda guidelines.
Author: Molinari, Francesca|Signoroni, Stefano|Lampis, Andrea|Bertan, Claudia|Perrone, Federica|Sala, Paola|Mondini, Patrizia|Crippa, Stefano|Bertario, Lucio|Frattini, Milo
PMID: 25076244
Journal: J Exp Clin Cancer Res. 2014 Aug 5;33:65.
Title: Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.
Author: Rengucci, Claudia|De Maio, Giulia|Casadei Gardini, Andrea|Zucca, Mattia|Scarpi, Emanuela|Zingaretti, Chiara|Foschi, Giovanni|Tumedei, Maria Maddalena|Molinari, Chiara|Saragoni, Luca|Puccetti, Maurizio|Amadori, Dino|Zoli, Wainer|Calistri, Daniele
PMID: 25091577
Journal: Pathologe. 2014 Nov;35(6):615-21; quiz 622-3.
Title: [Colorectal carcinoma in consideration of the new German S3 guideline 2013].
Author: Neumann, J H L|Kirchner, T
PMID: 25106124
Journal: Eur J Surg Oncol. 2014 Nov;40(11):1445-52.
Title: MLH1 and MSH2 mutation screening in HNPCC families of Hungary - Two new MMR gene mutations.
Author: Tanyi, M|Olasz, J|Tanyi, J L|Toth, L|Antal-Szalmas, P|Ress, Z|Buban, T|Palatka, K|Andras, C|Urbancsek, H|Garami, Z|Csuka, O|Damjanovich, L
PMID: 25107687
Journal: World J Gastroenterol. 2014 Aug 7;20(29):10050-61.
Title: IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.
Author: Naito, Takafumi|Nosho, Katsuhiko|Ito, Miki|Igarashi, Hisayoshi|Mitsuhashi, Kei|Yoshii, Shinji|Aoki, Hironori|Nomura, Masafumi|Sukawa, Yasutaka|Yamamoto, Eiichiro|Adachi, Yasushi|Takahashi, Hiroaki|Hosokawa, Masao|Fujita, Masahiro|Takenouchi, Toshinao|Maru
PMID: 25110432
Journal: Med Oncol. 2014 Sep;31(9):160.
Title: Effect of MLH1 -93G>A on gene expression in patients with colorectal cancer.
Author: Funck, Alexandre|Santos, Juliana C|Silva-Fernandes, Isabelle J L|Rabenhorst, Silvia H B|Martinez, Carlos A R|Ribeiro, Marcelo L
PMID: 25115745
Journal: Fam Cancer. 2014 Dec;13(4):573-82.
Title: High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry.
Author: Rosty, Christophe|Walsh, Michael D|Lindor, Noralane M|Thibodeau, Stephen N|Mundt, Erin|Gallinger, Steven|Aronson, Melyssa|Pollett, Aaron|Baron, John A|Pearson, Sally|Clendenning, Mark|Walters, Rhiannon J|Nagler, Belinda N|Crawford, William J|Young, Joanne
PMID: 25117503
Journal: PLoS One. 2014 Aug 18;9(8):e105501.
Title: The mutational spectrum of Lynch syndrome in cyprus.
Author: Loizidou, Maria A|Neophytou, Ioanna|Papamichael, Demetris|Kountourakis, Panteleimon|Vassiliou, Vassilios|Marcou, Yiola|Kakouri, Eleni|Ioannidis, Georgios|Philippou, Chrystalla|Spanou, Elena|Tanteles, George A|Anastasiadou, Violetta|Hadjisavvas, Andreas|Ky
PMID: 25133505
Journal: Hum Pathol. 2014 Oct;45(10):2029-36.
Title: How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation?
Author: Vilkin, Alex|Halpern, Marisa|Morgenstern, Sara|Brazovski, Eli|Gingold-Belfer, Rachel|Boltin, Doron|Purim, Ofer|Kundel, Yulia|Welinsky, Sara|Brenner, Baruch|Niv, Yaron|Levi, Zohar
PMID: 25150747
Journal: J Nutr Biochem. 2014 Nov;25(11):1196-1206.
Title: Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome.
Author: Dermadi, Denis|Valo, Satu|Pussila, Marjaana|Reyhani, Nima|Sarantaus, Laura|Lalowski, Maciej|Baumann, Marc|Nystrom, Minna
PMID: 25172634
Journal: Int J Clin Exp Pathol. 2014 Jul 15;7(8):5196-202. eCollection 2014.
Title: Synchronous gastric and sebaceous cancers, a rare manifestation of MLH1-related Muir-Torre syndrome.
Author: Svec, Jiri|Schwarzova, Lucie|Janosikova, Bohumila|Stekrova, Jitka|Mandys, Vaclav|Kment, Milan|Vodicka, Pavel
PMID: 25197397
Journal: Int J Surg. 2014;12 Suppl 2:S120-S124.
Title: Molecular screening in Sicilian families with hereditary non-poliposis colorectal cancer (H.N.P.C.C.) syndrome: identification of a novel mutation in MSH2 gene.
Author: Cavallaro, Andrea|Russo, Angela|Catania, Vito Emanuele|Ficili, Bartolomea|Romano, Fabrizio|Failla, Andrea Valentino|Cappellani, Alessandro|Cammisuli, Ferdinando|Viola, Maria|Madeddu, Roberto|Trichilo, Vincenzo|Libra, Massimo|Travali, Salvatore
PMID: 25200962
Journal: Zhonghua Bing Li Xue Za Zhi. 2014 Jun;43(6):394-8.
Title: [Screening for Lynch syndrome in colorectal cancer].
Author: Liu, Xiaohong|Cao, Yongcheng|Wang, Cuicui|Cao, Ruixue|Chen, Xin|Ding, Jiyuan|Geng, Ming
PMID: 25208990
Journal: Med Oncol. 2014 Oct;31(10):223.
Title: Clinicopathological and genetic features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC).
Author: Liu, Fangqi|Yang, Li|Zhou, Xiaoyan|Sheng, Weiqi|Cai, Sanjun|Liu, Lei|Nan, Peng|Xu, Ye
PMID: 25216868
Journal: Asian Pac J Cancer Prev. 2014;15(17):7091-5.
Title: Expression of BMP6 is associated with its methylation status in colorectal cancer tissue but lacks prognostic significance.
Author: Sangplod, Patcharaporn|Kanngurn, Samornmas|Boonpipattanapong, Teeranut|Ruangrat, Pritsana|Sangkhathat, Surasak
PMID: 25227796
Journal: Am J Surg Pathol. 2014 Nov;38(11):1501-9.
Title: Lynch syndrome screening should be considered for all patients with newly diagnosed endometrial cancer.
Author: Mills, Anne M|Liou, Sofia|Ford, James M|Berek, Jonathan S|Pai, Reetesh K|Longacre, Teri A
PMID: 25229768
Journal: Biomed Res Int. 2014;2014:236361.
Title: CpG island methylator phenotype and prognosis of colorectal cancer in Northeast China.
Author: Li, Xia|Hu, Fulan|Wang, Yibaina|Yao, Xiaoping|Zhang, Zuoming|Wang, Fan|Sun, Guizhi|Cui, Bin-Bin|Dong, Xinshu|Zhao, Yashuang
PMID: 25243122
Journal: Ann Surg Treat Res. 2014 Sep;87(3):123-30.
Title: hMLH1 promoter methylation and BRAF mutations in high-frequency microsatellite instability colorectal cancers not fulfilling the revised Bethesda guidelines.
Author: Kim, Sang Jin|Kim, Hyoung Ran|Kim, Seok Hyung|Han, Ji Hye|Cho, Yong Beom|Yun, Seong Hyeon|Lee, Woo Yong|Kim, Hee Cheol
PMID: 25247165
Journal: J Med Genet. 2014 Dec;51(12):789-96.
Title: Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC).
Author: Newton, K|Jorgensen, N M|Wallace, A J|Buchanan, D D|Lalloo, F|McMahon, R F T|Hill, J|Evans, D G
PMID: 25280751
Journal: Exp Ther Med. 2014 Nov;8(5):1416-1422.
Title: Clinical significance of mismatch repair gene expression in sporadic colorectal cancer.
Author: Sun, Zhenqiang|Yu, Xianbo|Wang, Haijiang|Zhang, Shuo|Zhao, Zeliang|Xu, Ruiwei
PMID: 25289032
Journal: Oncol Lett. 2014 Nov;8(5):1937-1944.
Title: A CpG island methylator phenotype of colorectal cancer that is contiguous with conventional adenomas, but not serrated polyps.
Author: Hokazono, Koji|Ueki, Takashi|Nagayoshi, Kinuko|Nishioka, Yasunobu|Hatae, Tatsunobu|Koga, Yutaka|Hirahashi, Minako|Oda, Yoshinao|Tanaka, Masao
PMID: 25289081
Journal: Oncogenesis. 2014 Oct 13;3:e121.
Title: MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death.
Author: Oka, S|Leon, J|Tsuchimoto, D|Sakumi, K|Nakabeppu, Y
PMID: 25310643
Journal: Hum Pathol. 2014 Dec;45(12):2430-6.
Title: Immunohistochemical detection of ARID1A in colorectal carcinoma: loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage.
Author: Ye, Jiqing|Zhou, Yi|Weiser, Martin R|Gonen, Mithat|Zhang, Liying|Samdani, Tushar|Bacares, Ruben|DeLair, Deborah|Ivelja, Sinisa|Vakiani, Efsevia|Klimstra, David S|Soslow, Robert A|Shia, Jinru
PMID: 25311944
Journal: Appl Clin Genet. 2014 Oct 6;7:183-93.
Title: Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome).
Author: Buchanan, Daniel D|Rosty, Christophe|Clendenning, Mark|Spurdle, Amanda B|Win, Aung Ko
PMID: 25328415
Journal: Curr Colorectal Cancer Rep. 2014 Sep 1;10(3):346-353.
Title: Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in KRAS, and BRAF(V600E) in Patients with Lymph Node-Positive Colon Cancer.
Author: Zaanan, Aziz|Bachet, Jean-Baptiste|Andre, Thierry|Sinicrope, Frank A
PMID: 25386108
Journal: Gastroenterol Res Pract. 2014;2014:527946.
Title: Report of a Novel Mutation in MLH1 Gene in a Hispanic Family from Puerto Rico Fulfilling Classic Amsterdam Criteria for Lynch Syndrome.
Author: Marques-Lespier, Juan M|Diaz-Algorri, Yaritza|Gonzalez-Pons, Maria|Cruz-Correa, Marcia
PMID: 25389437
Journal: Int J Clin Exp Pathol. 2014 Sep 15;7(10):7297-303. eCollection 2014.
Title: Role of endometrial cancer abnormal MMR protein in screening Lynch-syndrome families.
Author: Long, Qiongxian|Peng, Yong|Tang, Zhirong|Wu, Cailiang
PMID: 25400828
Journal: Epigenetics. 2014 Oct;9(10):1431-8.
Title: MLH1 constitutional and somatic methylation in patients with MLH1 negative tumors fulfilling the revised Bethesda criteria.
Author: Crucianelli, Francesca|Tricarico, Rossella|Turchetti, Daniela|Gorelli, Greta|Gensini, Francesca|Sestini, Roberta|Giunti, Laura|Pedroni, Monica|Ponz de Leon, Maurizio|Civitelli, Serenella|Genuardi, Maurizio
PMID: 25437057
Journal: Pharmacol Rep. 2014 Dec;66(6):1083-91.
Title: Celecoxib prevents colitis associated colon carcinogenesis: an upregulation of apoptosis.
Author: Setia, Shruti|Nehru, Bimla|Sanyal, Sankar N
PMID: 25443739
Journal: World J Gastroenterol. 2014 Dec 28;20(48):18338-45.
Title: Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer.
Author: Yan, Zhi-Hui|Cui, Li-Hong|Wang, Xiao-Hui|Li, Chao|He, Xing
PMID: 25561800
Journal: Rev Gastroenterol Peru. 2014 Oct-Dec;34(4):299-303.
Title: [Molecular characterization of hereditary colorectal cancer in Peru].
Author: Nique Carbajal, Cesar|Sanchez Renteria, Fernando|Lettiero, Barbara|Wernhoff, Patrik|Dominguez-Valentin, Mev
PMID: 25594752
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2014 Dec;48(12):1078-82.
Title: [The differences between three distinct locations of colorectal cancers based on clinicopathological characteristics and molecular features].
Author: Li, Cong|Wang, Zhimin|Zhao, Jiang|Cai, Sanjun|Xu, Ye|Liu, Fangqi
PMID: 25619220
Journal: Gan To Kagaku Ryoho. 2014 Nov;41(12):1602-4.
Title: [Tumor-infiltrating lymphocytes can be used to screen for lynch syndrome - a case report].
Author: Tanakaya, Kohji|Kanaya, Nobuhiko|Shigeyasu, Kunitoshi|Kunitomo, Tomoyoshi|Aoki, Hideki|Takeuchi, Hitoshi|Yamasaki, Rie
PMID: 25731267
Journal: Tunis Med. 2014 Jul;92(7):458-62.
Title: [Molecular characterization of Lynch syndrome in Tunisia].
Author: Sana, Aissi|Farid, Zerimech|Amel, Moussa|Nadia, Kourda|Amel, Mezlini|Nabil, Abdelli|Taoufik, Najjar|Farhat, Ben Ayed|Sarah, Ben Jilani|Mohamed, Manai|Marie-Pierre, Buisine
PMID: 25775284
Journal: Tunis Med. 2014 Oct;92(10):622-5.
Title: [Immunohistochemical analysis of mismatch repair proteins in colorectal adenomas].
Author: Rammeh, Soumaya|Sabbegh Znaidi, Nadia|Arfaoui, Amira|Ayouni, Kaouther|Blel, Ahlem|Farah, Faten|Zidi, Yosra|Najjar, Taoufik|Kourda, Nadia|Said, Yosra|Zermani, Rachida
PMID: 25860677
Journal:
Title:
Author: Meleth, Sreelatha|Reeder-Hayes, Katherine|Ashok, Mahima|Clark, Robert|Funkhouser, William|Wines, Roberta|Hill, Christine|Shanahan, Ellen|McClure, Emily|Burson, Katrina|Coker-Schwimmer, Manny|Garge, Nikhil|Jonas, Daniel E
PMID: 25905152
Journal: Endosc Int Open. 2014 Dec;2(4):E252-5.
Title: Quality of colonoscopy in Lynch syndrome.
Author: Niv, Yaron|Moeslein, Gabriela|Vasen, Hans F A|Karner-Hanusch, Judith|Lubinsky, Jan|Gasche, Christoph
PMID: 26135102
Journal: Life Sci Space Res (Amst). 2014 Apr;1:67-73.
Title: Inhibition of microRNA-31-5p protects human colonic epithelial cells against ionizing radiation.
Author: Kim, Sang Bum|Zhang, Lu|Barron, Summer|Shay, Jerry W
PMID: 26432591
Journal: Fam Cancer. 2015 Dec;14(4):553-9.
Title: Survival in familial colorectal cancer: a Danish cohort study.
Author: Lautrup, Charlotte Kvist|Mikkelsen, Ellen M|Lash, Timothy L|Katballe, Niels|Sunde, Lone
PMID: 12696065
Journal: Mod Pathol. 2015 Jan;28(1):146-58.
Title: Distinct WNT/beta-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum.
Author: Murakami, Takashi|Mitomi, Hiroyuki|Saito, Tsuyoshi|Takahashi, Michiko|Sakamoto, Naoto|Fukui, Naoshi|Yao, Takashi|Watanabe, Sumio
PMID: 24925057
Journal: Clin Genet. 2015 Jun;87(6):543-8.
Title: Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.
Author: Pineda, M|Gonzalez-Acosta, M|Thompson, B A|Sanchez, R|Gomez, C|Martinez-Lopez, J|Perea, J|Caldes, T|Rodriguez, Y|Landolfi, S|Balmana, J|Lazaro, C|Robles, L|Capella, G|Rueda, D
PMID: 25060679
Journal: Int J Cancer. 2015 Apr 1;136(7):1568-78.
Title: Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers.
Author: Kang, So Young|Park, Cheol Keun|Chang, Dong Kyung|Kim, Jong Won|Son, Hee Jung|Cho, Yong Beom|Yun, Seong Hyeon|Kim, Hee Cheol|Kwon, Moosik|Kim, Kyoung-Mee
PMID: 25110875
Journal: Int J Cancer. 2015 Mar 15;136(6):E559-68.
Title: Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.
Author: Kraus, Cornelia|Rau, Tilman T|Lux, Philipp|Erlenbach-Wunsch, Katharina|Lohr, Sabine|Krumbiegel, Mandy|Thiel, Christian T|Stohr, Robert|Agaimy, Abbas|Croner, Roland S|Sturzl, Michael|Hohenberger, Werner|Hartmann, Arndt|Reis, Andre
PMID: 25142776
Journal: Fam Cancer. 2015 Mar;14(1):77-80.
Title: MLH1 promotor hypermethylation does not rule out a diagnosis of Lynch syndrome: a case report.
Author: Raymond, Victoria M|Morris, Arden M|Hafez, Khaled S|Greenson, Joel K
PMID: 25213678
Journal: Mod Pathol. 2015 Mar;28(3):414-27.
Title: A clinicopathological and molecular analysis of 200 traditional serrated adenomas.
Author: Bettington, Mark L|Walker, Neal I|Rosty, Christophe|Brown, Ian S|Clouston, Andrew D|McKeone, Diane M|Pearson, Sally-Ann|Klein, Kerenaftali|Leggett, Barbara A|Whitehall, Vicki L J
PMID: 25216220
Journal: Gynecol Oncol. 2015 Jan;136(1):3-7.
Title: Society of Gynecologic Oncology statement on risk assessment for inherited gynecologic cancer predispositions.
Author: Lancaster, Johnathan M|Powell, C Bethan|Chen, Lee-May|Richardson, Debra L
PMID: 25238946
Journal: Tumour Biol. 2015 Jan;36(1):279-89.
Title: Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan.
Author: Djansugurova, Leyla|Zhunussova, Gulnur|Khussainova, Elmira|Iksan, Olzhas|Afonin, Georgiy|Kaidarova, Dilyara|Parker, M Iqbal
PMID: 25249451
Journal: Int J Colorectal Dis. 2015 Mar;30(3):435-6.
Title: Letter to the editor: rectal cancer in a 15-year-old female with a novel MLH1 and MSH6 biallelic inheritance.
Author: Fretwell, Victoria|Rooney, Paul
PMID: 25287593
Journal: Gastroenterology. 2015 Jan;148(1):88-99.
Title: Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes.
Author: Sinicrope, Frank A|Shi, Qian|Smyrk, Thomas C|Thibodeau, Stephen N|Dienstmann, Rodrigo|Guinney, Justin|Bot, Brian M|Tejpar, Sabine|Delorenzi, Mauro|Goldberg, Richard M|Mahoney, Michelle|Sargent, Daniel J|Alberts, Steven R
PMID: 25305506
Journal: Br J Cancer. 2015 Jan 20;112(2):403-12.
Title: B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P.
Author: Inoue, A|Okamoto, K|Fujino, Y|Nakagawa, T|Muguruma, N|Sannomiya, K|Mitsui, Y|Takaoka, T|Kitamura, S|Miyamoto, H|Okahisa, T|Fujimori, T|Imoto, I|Takayama, T
PMID: 25314065
Journal: Genet Med. 2015 Jun;17(6):476-84.
Title: Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair-deficient tumors.
Author: Dempsey, Katherine M|Broaddus, Russell|You, Y Nancy|Noblin, Sarah Jane|Mork, Maureen|Fellman, Bryan|Urbauer, Diana|Daniels, Molly|Lu, Karen
PMID: 25341111
Journal: Clin Genet. 2015 Jun;87(6):507-16.
Title: Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome.
Author: Ponti, G|Castellsague, E|Ruini, C|Percesepe, A|Tomasi, A
PMID: 25345868
Journal: Zentralbl Chir. 2015 Dec;140(6):591-9.
Title: [Colorectal Carcinoma with Suspected Lynch Syndrome: A Multidisciplinary Algorithm].
Author: Schneider, R|Schneider, C|Buttner, R|Reinacher-Schick, A|Tannapfel, A|Furst, A|Ruschoff, J|Jakobeit, C|Royer-Pokora, B|Moslein, G
PMID: 25372301
Journal: Ann Surg Oncol. 2015 May;22(5):1504-12.
Title: Histologic categorization of desmoplastic reaction: its relevance to the colorectal cancer microenvironment and prognosis.
Author: Ueno, Hideki|Shinto, Eiji|Shimazaki, Hideyuki|Kajiwara, Yoshiki|Sueyama, Takahiro|Yamamoto, Junji|Hase, Kazuo
PMID: 25395146
Journal: Mol Carcinog. 2015 Dec;54(12):1807-14.
Title: Evidence for presence of mismatch repair gene expression positive Lynch syndrome cases in India.
Author: Bashyam, Murali D|Kotapalli, Viswakalyan|Raman, Ratheesh|Chaudhary, Ajay K|Yadav, Brijesh K|Gowrishankar, Swarnalata|Uppin, Shantveer G|Kongara, Ravikanth|Sastry, Regulagadda A|Vamsy, Mohana|Patnaik, Sujit|Rao, Satish|Dsouza, Shoba|Desai, Devendra|Tester,
PMID: 25420488
Journal: Oncol Lett. 2015 Jan;9(1):183-186.
Title: A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient.
Author: Vodicka, Pavel|Caja, Fabian|Vymetalkova, Veronika|Prochazka, Pavel|Vodickova, Ludmila|Schwarzova, Lucie|Slyskova, Jana|Kumar, Rajiv|Schneiderova, Michaela
PMID: 25435955
Journal: Pathol Res Pract. 2015 Jan;211(1):78-82.
Title: Sebaceous neoplasms and the immunoprofile of mismatch-repair proteins as a screening target for syndromic cases.
Author: Boennelycke, Marie|Thomsen, Birthe M|Holck, Susanne
PMID: 25457183
Journal: Gastroenterology. 2015 Mar;148(3):556-64.
Title: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author: Grant, Robert C|Selander, Iris|Connor, Ashton A|Selvarajah, Shamini|Borgida, Ayelet|Briollais, Laurent|Petersen, Gloria M|Lerner-Ellis, Jordan|Holter, Spring|Gallinger, Steven
PMID: 25479140
Journal: Genes Nutr. 2015 Jan;10(1):448.
Title: Interactions between meat intake and genetic variation in relation to colorectal cancer.
Author: Andersen, Vibeke|Vogel, Ulla
PMID: 25491747
Journal: Cancer Sci. 2015 Mar;106(3):217-26.
Title: Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice.
Author: Morioka, Takamitsu|Miyoshi-Imamura, Tomoko|Blyth, Benjamin J|Kaminishi, Mutsumi|Kokubo, Toshiaki|Nishimura, Mayumi|Kito, Seiji|Tokairin, Yutaka|Tani, Shusuke|Murakami-Murofushi, Kimiko|Yoshimi, Naoki|Shimada, Yoshiya|Kakinuma, Shizuko
PMID: 25529563
Journal: Int J Cancer. 2015 Jul 15;137(2):320-31.
Title: Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas.
Author: Spier, Isabel|Holzapfel, Stefanie|Altmuller, Janine|Zhao, Bixiao|Horpaopan, Sukanya|Vogt, Stefanie|Chen, Sophia|Morak, Monika|Raeder, Susanne|Kayser, Katrin|Stienen, Dietlinde|Adam, Ronja|Nurnberg, Peter|Plotz, Guido|Holinski-Feder, Elke|Lifton, Richard P
PMID: 25529843
Journal: J Clin Oncol. 2015 Feb 1;33(4):326-31.
Title: Short-term risk of colorectal cancer in individuals with lynch syndrome: a meta-analysis.
Author: Jenkins, Mark A|Dowty, James G|Ait Ouakrim, Driss|Mathews, John D|Hopper, John L|Drouet, Youenn|Lasset, Christine|Bonadona, Valerie|Win, Aung Ko
PMID: 25534380
Journal: Pathol Res Pract. 2015 Feb;211(2):171-4.
Title: Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer.
Author: Al-Nomani, Lukman|Friedrichs, Jacqueline|Schule, Roland|Buttner, Reinhard|Friedrichs, Nicolaus
PMID: 25554651
Journal: Cancer. 2015 May 1;121(9):1395-404.
Title: Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer.
Author: Moreira, Leticia|Munoz, Jenifer|Cuatrecasas, Miriam|Quintanilla, Isabel|Leoz, Maria Liz|Carballal, Sabela|Ocana, Teresa|Lopez-Ceron, Maria|Pellise, Maria|Castellvi-Bel, Sergi|Jover, Rodrigo|Andreu, Montserrat|Carracedo, Angel|Xicola, Rosa Maria|Llor, Xavi
PMID: 25557234
Journal: J Clin Oncol. 2015 Feb 10;33(5):426-32.
Title: Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
Author: Chubb, Daniel|Broderick, Peter|Frampton, Matthew|Kinnersley, Ben|Sherborne, Amy|Penegar, Steven|Lloyd, Amy|Ma, Yussanne P|Dobbins, Sara E|Houlston, Richard S
PMID: 25559809
Journal: J Cancer Res Clin Oncol. 2015 Aug;141(8):1393-404.
Title: Intronic and promoter polymorphisms of hMLH1/hMSH2 and colorectal cancer risk in Heilongjiang Province of China.
Author: Li, Guangxiao|Hu, Fulan|Yuan, Fengshun|Fan, Jialong|Yu, Zhifu|Wu, Zhiwei|Zhao, Xiaojuan|Li, Ye|Li, Shuying|Rong, Jiesheng|Cui, Binbin|Dong, Xinshu|Yuan, Huiping|Zhao, Yashuang
PMID: 25560462
Journal: Tumour Biol. 2015 May;36(5):3853-61.
Title: Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.
Author: Veganzones, S|Maestro, M L|Rafael, S|de la Orden, V|Vidaurreta, M|Mediero, B|Espantaleon, M|Cerdan, J|Diaz-Rubio, E
PMID: 25576161
Journal: Am J Surg Pathol. 2015 Mar;39(3):313-7.
Title: Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of Wnt signaling activation.
Author: Panarelli, Nicole C|Vaughn, Cecily P|Samowitz, Wade S|Yantiss, Rhonda K
PMID: 25602793
Journal: Digestion. 2015;91(1):57-63.
Title: Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author: Nosho, Katsuhiko|Igarashi, Hisayoshi|Ito, Miki|Mitsuhashi, Kei|Kurihara, Hiroyoshi|Kanno, Shinichi|Yoshii, Shinji|Mikami, Masashi|Takahashi, Hiroaki|Kusumi, Takaya|Hosokawa, Masao|Sukawa, Yasutaka|Adachi, Yasushi|Hasegawa, Tadashi|Okita, Kenji|Hirata, Koi
PMID: 25632919
Journal: Medicine (Baltimore). 2015 Jan;94(4):e493.
Title: A case of mucinous adenocarcinoma in the setting of chronic colitis associated with intestinal spirochetosis and intestinal stricture.
Author: Akiyama, Shintaro|Kikuchi, Daisuke|Mitani, Toshifumi|Fujii, Takeshi|Yamada, Akihiro|Matsui, Akira|Ogawa, Osamu|Iizuka, Toshiro|Hoteya, Shu|Kaise, Mitsuru
PMID: 25634199
Journal: Tumour Biol. 2015 Jun;36(6):4661-70.
Title: Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population.
Author: Laskar, Ruhina S|Talukdar, Fazlur R|Choudhury, Javed H|Singh, Seram Anil|Kundu, Sharbadeb|Dhar, Bishal|Mondal, Rosy|Ghosh, Sankar Kumar
PMID: 25647260
Journal: World J Gastroenterol. 2015 Feb 7;21(5):1595-605.
Title: KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.
Author: Ye, Ju-Xiang|Liu, Yan|Qin, Yun|Zhong, Hao-Hao|Yi, Wei-Ning|Shi, Xue-Ying
PMID: 25663779
Journal: J Comp Pathol. 2015 Feb-Apr;152(2-3):131-7.
Title: Mismatch repair mRNA and protein expression in intestinal adenocarcinoma in sika deer (Cervus nippon) resembling heritable non-polyposis colorectal cancer in man.
Author: Jahns, H|Browne, J A
PMID: 25678423
Journal: Arch Toxicol. 2015 Jun;89(6):899-921.
Title: Microsatellite instability: an update.
Author: Yamamoto, Hiroyuki|Imai, Kohzoh
PMID: 25701956
Journal: Semin Diagn Pathol. 2015 Sep;32(5):352-61.
Title: Evolving approach and clinical significance of detecting DNA mismatch repair deficiency in colorectal carcinoma.
Author: Shia, Jinru
PMID: 25716099
Journal: J Gastrointest Cancer. 2015 Jun;46(2):118-25.
Title: Molecular analysis of Iranian colorectal cancer patients at risk for Lynch syndrome: a new molecular, clinicopathological feature.
Author: Zeinalian, Mehrdad|Emami, Mohammad Hassan|Salehi, Rasoul|Naimi, Azar|Kazemi, Mohammad|Hashemzadeh-Chaleshtori, Morteza
PMID: 25722176
Journal: Carcinogenesis. 2015 Apr;36(4):452-8.
Title: Concomitant mutation and epimutation of the MLH1 gene in a Lynch syndrome family.
Author: Cini, Giulia|Carnevali, Ileana|Quaia, Michele|Chiaravalli, Anna Maria|Sala, Paola|Giacomini, Elisa|Maestro, Roberta|Tibiletti, Maria Grazia|Viel, Alessandra
PMID: 25742745
Journal: Tohoku J Exp Med. 2015 Feb;235(2):117-25.
Title: Efficient screening strategy for Lynch syndrome in Japanese endometrial cancer.
Author: Sugawara, Tae|Sato, Naoki|Shimizu, Dai|Sato, Toshiharu|Makino, Kenichi|Kito, Masahiko|Tamura, Daisuke|Kato, Aya|Terada, Yukihiro
PMID: 25745978
Journal: Pathobiology. 2015 Feb 28;82(1):36-42.
Title: Absence of Microsatellite Instability In Soft Tissue Sarcomas.
Author: Campanella, Nathalia C|Penna, Valter|Ribeiro, Guilherme|Abrahao-Machado, Lucas Faria|Scapulatempo-Neto, Cristovam|Reis, Rui Manuel
PMID: 25766089
Journal: Cancer Biomark. 2015;15(3):227-33.
Title: DNMT3b -149C/T promoter variants and methylation of colorectal cancer-associated genes.
Author: Naghibalhossaini, Fakhraddin|Mokarram, Pooneh|Khalili, Eslam|Naghibalhossaini, Samaneh
PMID: 25769449
Journal: Mol Oncol. 2015 Jun;9(6):1207-17.
Title: Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.
Author: Sonderstrup, Ida Marie Heeholm|Nygard, Sune Boris|Poulsen, Tim Svenstrup|Linnemann, Dorte|Stenvang, Jan|Nielsen, Hans Jorgen|Bartek, Jiri|Brunner, Nils|Norgaard, Peter|Riis, Lene
PMID: 25777966
Journal: Fam Cancer. 2015 Sep;14(3):415-25.
Title: Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome.
Author: Cruz-Correa, Marcia|Diaz-Algorri, Yaritza|Perez-Mayoral, Julyann|Suleiman-Suleiman, Wasilah|Gonzalez-Pons, Maria del Mar|Bertran, Carlos|Casellas, Nicolas|Rodriguez, Natalia|Pardo, Sherly|Rivera, Keyla|Mosquera, Rafael|Rodriguez-Quilichini, Segundo
PMID: 25782445
Journal: Obstet Gynecol Sci. 2015 Mar;58(2):112-6.
Title: Characteristics of hereditary nonpolyposis colorectal cancer patients with double primary cancers in endometrium and colorectum.
Author: Shin, So Hyun|Yu, Eun Jeong|Lee, Yoo-Kyung|Song, Yong-Sang|Seong, Moon-Woo|Park, Sung Sup
PMID: 25798424
Journal: PLoS One. 2015 Mar 27;10(3):e0123396.
Title: DNA methylation combinations in adjacent normal colon tissue predict cancer recurrence: evidence from a clinical cohort study.
Author: Kuan, Jen Chun|Wu, Chang Chieh|Sun, Chien An|Chu, Chi Ming|Lin, Fu Gong|Hsu, Chih Hsiung|Kan, Po-Chieh|Lin, Shih-Chieh|Yang, Tsan|Chou, Yu-Ching
PMID: 25815725
Journal: PLoS One. 2015 Mar 27;10(3):e0121980.
Title: Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.
Author: Staffa, Laura|Echterdiek, Fabian|Nelius, Nina|Benner, Axel|Werft, Wiebke|Lahrmann, Bernd|Grabe, Niels|Schneider, Martin|Tariverdian, Mirjam|von Knebel Doeberitz, Magnus|Blaker, Hendrik|Kloor, Matthias
PMID: 25816162
Journal: Iran J Cancer Prev. 2015 Jan-Feb;8(1):11-7.
Title: Immunohistochemical analysis of mismatch repair proteins in Iranian colorectal cancer patients at risk for lynch syndrome.
Author: Zeinalian, Mehrdad|Emami, Mohammad Hassan|Naimi, Azar|Salehi, Rasoul|Hashemzadeh-Chaleshtori, Morteza
PMID: 25821566
Journal: Am J Surg Pathol. 2015 Aug;39(8):1114-20.
Title: Germline MLH1 Mutations Are Frequently Identified in Lynch Syndrome Patients With Colorectal and Endometrial Carcinoma Demonstrating Isolated Loss of PMS2 Immunohistochemical Expression.
Author: Dudley, Beth|Brand, Randall E|Thull, Darcy|Bahary, Nathan|Nikiforova, Marina N|Pai, Reetesh K
PMID: 25871621
Journal: World J Gastroenterol. 2015 Apr 14;21(14):4136-49.
Title: Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.
Author: Zhang, Jun-Xiao|Fu, Lei|de Voer, Richarda M|Hahn, Marc-Manuel|Jin, Peng|Lv, Chen-Xi|Verwiel, Eugene Tp|Ligtenberg, Marjolijn Jl|Hoogerbrugge, Nicoline|Kuiper, Roland P|Sheng, Jian-Qiu|Geurts van Kessel, Ad
PMID: 25892863
Journal: Exp Biol Med (Maywood). 2015 Dec;240(12):1599-605.
Title: Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma.
Author: Michailidi, Christina|Theocharis, Stamatios|Tsourouflis, Gerasimos|Pletsa, Vasiliki|Kouraklis, Gregorios|Patsouris, Efstratios|Papavassiliou, Athanasios G|Troungos, Constantinos
PMID: 25908636
Journal: J Med Genet. 2015 Jul;52(7):498-502.
Title: Prevalence of MLH1 constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer.
Author: Castillejo, Adela|Hernandez-Illan, Eva|Rodriguez-Soler, Maria|Perez-Carbonell, Lucia|Egoavil, Cecilia|Barbera, Victor M|Castillejo, Maria-Isabel|Guarinos, Carla|Martinez-de-Duenas, Eduardo|Juan, Maria-Jose|Sanchez-Heras, Ana-Beatriz|Garcia-Casado, Zaida|R
PMID: 25908759
Journal: BMC Cancer. 2015 Apr 25;15:313.
Title: A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients.
Author: Snowsill, Tristan|Huxley, Nicola|Hoyle, Martin|Jones-Hughes, Tracey|Coelho, Helen|Cooper, Chris|Frayling, Ian|Hyde, Chris
PMID: 25910169
Journal: Digestion. 2015;91(4):286-93.
Title: Tumor and Patient Characteristics of Individuals with Mismatch Repair Deficient Colorectal Cancer.
Author: Waldmann, Elisabeth|Ferlitsch, Monika|Binder, Nicolas|Sellner, Franz|Karner, Josef|Heinisch, Birgit|Klimpfinger, Martin|Trauner, Michael
PMID: 25924923
Journal: Epigenomics. 2015;7(2):175-86.
Title: Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer.
Author: Coppede, Fabio|Grossi, Enzo|Lopomo, Angela|Spisni, Roberto|Buscema, Massimo|Migliore, Lucia
PMID: 25942531
Journal: BMC Cancer. 2015 May 10;15:384.
Title: Randomized phase III clinical trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or
Author: Pectasides, Dimitrios|Karavasilis, Vasilios|Papaxoinis, George|Gourgioti, Georgia|Makatsoris, Thomas|Raptou, Georgia|Vrettou, Eleni|Sgouros, Joseph|Samantas, Epaminontas|Basdanis, George|Papakostas, Pavlos|Bafaloukos, Dimitrios|Kotoula, Vassiliki|Kalofono
PMID: 25956750
Journal: Fam Cancer. 2015 Dec;14(4):545-51.
Title: Childhood cancers in families with and without Lynch syndrome.
Author: Heath, John A|Reece, Jeanette C|Buchanan, Daniel D|Casey, Graham|Durno, Carol A|Gallinger, Steven|Haile, Robert W|Newcomb, Polly A|Potter, John D|Thibodeau, Stephen N|Le Marchand, Loic|Lindor, Noralane M|Hopper, John L|Jenkins, Mark A|Win, Aung Ko
PMID: 25963852
Journal: Fam Cancer. 2015 Dec;14(4):553-9.
Title: Survival in familial colorectal cancer: a Danish cohort study.
Author: Lautrup, Charlotte Kvist|Mikkelsen, Ellen M|Lash, Timothy L|Katballe, Niels|Sunde, Lone
PMID: 25963853
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015.
Title: Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Author: Kim, Jung Ho|Cho, Nam-Yun|Bae, Jeong Mo|Kim, Kyung-Ju|Rhee, Ye-Young|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 25973084
Journal: J Cancer Res Clin Oncol. 2015 Dec;141(12):2147-58.
Title: Association between MutL homolog 1 polymorphisms and the risk of colorectal cancer: a meta-analysis.
Author: Chen, Haiyan|Shen, Zhujing|Hu, Yeting|Xiao, Qian|Bei, Dikai|Shen, Xiangfeng|Ding, Kefeng
PMID: 25986311
Journal: Asian Pac J Cancer Prev. 2015;16(9):3767-71.
Title: Analysis of Hereditary Nonpolyposis Colorectal Cancer in Malay Cohorts using Immunohistochemical Screening.
Author: Wan Juhari, Wan Khairunnisa|Wan Abdul Rahman, Wan Faiziah|Mohd Sidek, Ahmad Shanwani|Abu Hassan, Muhammad Radzi|Ahmad Amin Noordin, Khairul Bariah|Zakaria, Andee Dzulkarnaen|Macrae, Finlay|Zilfalil, Bin Alwi
PMID: 25987035
Journal: Arch Pathol Lab Med. 2015 Jun;139(6):730-41.
Title: Molecular and histologic considerations in the assessment of serrated polyps.
Author: Yang, Hui-Min|Mitchell, James M|Sepulveda, Jorge L|Sepulveda, Antonia R
PMID: 26030242
Journal: Curr Treat Options Oncol. 2015 Jul;16(7):30.
Title: Microsatellite instability testing and its role in the management of colorectal cancer.
Author: Kawakami, Hisato|Zaanan, Aziz|Sinicrope, Frank A
PMID: 26031544
Journal: PLoS One. 2015 Jun 4;10(6):e0128202.
Title: Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations.
Author: Li, Wenbin|Zhi, Wenxue|Zou, Shuangmei|Qiu, Tian|Ling, Yun|Shan, Ling|Shi, Susheng|Ying, Jianming
PMID: 26042813
Journal: Int J Hyperthermia. 2015;31(5):464-75.
Title: Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines.
Author: Sottile, Mayra L|Losinno, Antonella D|Fanelli, Mariel A|Cuello-Carrion, F Dario|Montt-Guevara, M Magdalena|Vargas-Roig, Laura M|Nadin, Silvina B
PMID: 26043026
Journal: Orv Hetil. 2015 Jun 14;156(24):979-84.
Title: [The tip of the iceberg: multiple cutaneous sebaceous tumor in colon cancer. Muir-Torre syndrome--case report].
Author: Herr, Gyula|Szenes, Maria|Hohl, Gyorgyi|Vinkler, Marta Erzsebet|Tuske, Gyorgy|Horvath, Janos|Nagy, Gyongyi|Tihanyi, Mariann|Szell, Marta|Nagy, Nikoletta|Gasztonyi, Beata
PMID: 26051134
Journal: PLoS One. 2015 Jun 8;10(6):e0130018.
Title: Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome.
Author: Kamiza, Abram Bunya|Hsieh, Ling-Ling|Tang, Reiping|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|Wang, Chun-Yi|You, Jeng-Fu|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 26053027
Journal: Cancer Prev Res (Phila). 2015 Aug;8(8):702-11.
Title: Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.
Author: Ichimura, Norihisa|Shinjo, Keiko|An, Byonggu|Shimizu, Yasuhiro|Yamao, Kenji|Ohka, Fumiharu|Katsushima, Keisuke|Hatanaka, Akira|Tojo, Masayuki|Yamamoto, Eiichiro|Suzuki, Hiromu|Ueda, Minoru|Kondo, Yutaka
PMID: 26063725
Journal: World J Gastroenterol. 2015 Jun 14;21(22):6861-71.
Title: Advances in the study of Lynch syndrome in China.
Author: Lu, Jun-Yu|Sheng, Jian-Qiu
PMID: 26078562
Journal: Pathol Res Pract. 2015 Aug;211(8):601-9.
Title: Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system.
Author: Michl, Marlies|Heinemann, Volker|Jung, Andreas|Engel, Jutta|Kirchner, Thomas|Neumann, Jens
PMID: 26092596
Journal: Int J Mol Med. 2015 Aug;36(2):511-7.
Title: Multivariate analysis as a method for evaluating the pathogenicity of novel genetic MLH1 variants in patients with colorectal cancer and microsatellite instability.
Author: Duraturo, Francesca|Liccardo, Raffaella|Cavallo, Angela|De Rosa, Marina|Rossi, Giovanni Battista|Izzo, Paola
PMID: 26096739
Journal: Am J Surg Pathol. 2015 Oct;39(10):1370-6.
Title: Heterogenous MSH6 loss is a result of microsatellite instability within MSH6 and occurs in sporadic and hereditary colorectal and endometrial carcinomas.
Author: Graham, Rondell P|Kerr, Sarah E|Butz, Malinda L|Thibodeau, Stephen N|Halling, Kevin C|Smyrk, Thomas C|Dina, Michelle A|Waugh, Victoria M|Rumilla, Kandelaria M
PMID: 26099011
Journal: Diagn Pathol. 2015 Jun 24;10:77.
Title: Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.
Author: Sekal, Mohammed|Ameurtesse, Hassania|Chbani, Laila|Ouldim, Karim|Bennis, Sanae|Abkari, Mohammed|Boulouz, Amal|Benajah, Dafr Allah|Benjelloun, Basher|Ousadden, Abdelmalek|Ait Taleb, Khalid|Ait Laalim, Said|Toghrai, Imane|Mazaz, Khalid|Arifi, Samia|Mellas,
PMID: 26104511
Journal: J Natl Cancer Inst. 2015 Jun 24;107(9). pii: djv170.
Title: Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome.
Author: Ait Ouakrim, Driss|Dashti, Seyedeh Ghazaleh|Chau, Rowena|Buchanan, Daniel D|Clendenning, Mark|Rosty, Christophe|Winship, Ingrid M|Young, Joanne P|Giles, Graham G|Leggett, Barbara|Macrae, Finlay A|Ahnen, Dennis J|Casey, Graham|Gallinger, Steven|Haile, Robe
PMID: 26109217
Journal: Tumour Biol. 2015 Dec;36(12):9599-609.
Title: Association between mismatch repair gene and irinotecan-based chemotherapy in metastatic colon cancer.
Author: Ma, Junli|Zhang, Yan|Shen, Hong|Kapesa, Linda|Liu, Wenqiang|Zeng, Mengsi|Zeng, Shan
PMID: 26142736
Journal: Gene. 2015 Oct 10;570(2):304-5.
Title: Segregation of a novel MLH1 mutation in an Iranian Lynch syndrome family.
Author: Ghafouri-Fard, Soudeh|Fardaei, Majid|Lankarani, Kamran Bagheri|Miryounesi, Mohammad
PMID: 26149658
Journal: World J Gastroenterol. 2015 Jul 7;21(25):7916-20.
Title: Intraductal papillary mucinous neoplasm of the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer: A case report.
Author: Lee, Sang Hwa|Kim, Wook Youn|Hwang, Dae-Yong|Han, Hye Seung
PMID: 26167093
Journal: Ann Clin Biochem. 2015 Nov;52(Pt 6):690-2.
Title: The Mendelian colorectal cancer syndromes.
Author: Tomlinson, Ian
PMID: 26169059
Journal: Oncotarget. 2015 Sep 15;6(27):23820-36.
Title: LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer.
Author: Zhuo, Changhua|Li, Qingguo|Wu, Yuchen|Li, Yiwei|Nie, Jia|Li, Dawei|Peng, Junjie|Lian, Peng|Li, Bin|Cai, Guoxiang|Li, Xinxiang|Cai, Sanjun
PMID: 26172297
Journal: Cancer Lett. 2015 Oct 10;367(1):34-42.
Title: Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors.
Author: Lee, Sun-Hwa|Hong, Jun Hwa|Park, Hwan Ki|Park, Jun Seok|Kim, Bo-Kyung|Lee, Jung-Yi|Jeong, Ji Yun|Yoon, Ghil Suk|Inoue, Masahiro|Choi, Gyu-Seog|Lee, In-Kyu
PMID: 26185002
Journal: Jpn J Clin Oncol. 2015 Oct;45(10):993-7.
Title: A novel deletion in the splice donor site of MLH1 exon 6 in a Japanese colon cancer patient with Lynch syndrome.
Author: Yamaguchi, Junya|Sato, Yuri|Kita, Mizuho|Nomura, Sachio|Yamamoto, Noriko|Kato, Yo|Ishikawa, Yuichi|Arai, Masami
PMID: 26185136
Journal: Int J Clin Exp Pathol. 2015 May 1;8(5):5938-43. eCollection 2015.
Title: Occurrence of colon tumors in a 16-year-old Japanese boy after hematopoietic stem cell transplantation for Diamond Blackfan anemia at age of 4: a case report.
Author: Matsuda, Ikuo|Tsuchida, Yasu-aki|Toyoshima, Fumihiko|Tozawa, Katsuyuki|Ikehara, Hisatomo|Ohda, Yoshio|Hori, Kazutoshi|Ohtsuka, Yoshitoshi|Watari, Jiro|Miwa, Hiroto|Hirota, Seiichi
PMID: 26191323
Journal: J Clin Pathol. 2015 Dec;68(12):1036-9.
Title: Screening for Lynch syndrome and referral to clinical genetics by selective mismatch repair protein immunohistochemistry testing: an audit and cost analysis.
Author: Colling, Richard|Church, David N|Carmichael, Juliet|Murphy, Lucinda|East, James|Risby, Peter|Kerr, Rachel|Chetty, Runjan|Wang, Lai Mun
PMID: 26201544
Journal: Fam Cancer. 2015 Dec;14(4):575-83.
Title: Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene.
Author: Win, Aung Ko|Reece, Jeanette C|Buchanan, Daniel D|Clendenning, Mark|Young, Joanne P|Cleary, Sean P|Kim, Hyeja|Cotterchio, Michelle|Dowty, James G|MacInnis, Robert J|Tucker, Katherine M|Winship, Ingrid M|Macrae, Finlay A|Burnett, Terrilea|Le Marchand, Loic
PMID: 26202870
Journal: Mod Pathol. 2015 Oct;28(10):1383-9.
Title: Mismatch repair status may predict response to adjuvant chemotherapy in resectable pancreatic ductal adenocarcinoma.
Author: Riazy, Maziar|Kalloger, Steve E|Sheffield, Brandon S|Peixoto, Renata D|Li-Chang, Hector H|Scudamore, Charles H|Renouf, Daniel J|Schaeffer, David F
PMID: 26226846
Journal: Jpn J Clin Oncol. 2015 Oct;45(10):987-92.
Title: A case of early onset rectal cancer of Lynch syndrome with a novel deleterious PMS2 mutation.
Author: Nomura, Sachio|Fujimoto, Yoshiya|Yamamoto, Noriko|Sato, Yuri|Ashihara, Yuumi|Kita, Mizuho|Yamaguchi, Junya|Ishikawa, Yuichi|Ueno, Masashi|Arai, Masami
PMID: 26232782
Journal: Pol J Pathol. 2015 Jun;66(2):109-20.
Title: Can the histological type of colorectal cancer determine the carcinogenesis pathway?
Author: Kolos, Malgorzata|Wasaznik-Jedras, Anna|Nasierowska-Guttmejer, Anna
PMID: 26247523
Journal: Br J Cancer. 2015 Aug 11;113(4):686-92.
Title: Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.
Author: Pinheiro, Manuela|Pinto, Carla|Peixoto, Ana|Veiga, Isabel|Lopes, Paula|Henrique, Rui|Baldaia, Helena|Carneiro, Fatima|Seruca, Raquel|Tomlinson, Ian|Kovac, Michal|Heinimann, Karl|Teixeira, Manuel R
PMID: 26247575
Journal: Gastroenterology. 2015 Nov;149(6):1446-53.
Title: Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome.
Author: Guindalini, Rodrigo Santa Cruz|Win, Aung Ko|Gulden, Cassandra|Lindor, Noralane M|Newcomb, Polly A|Haile, Robert W|Raymond, Victoria|Stoffel, Elena|Hall, Michael|Llor, Xavier|Ukaegbu, Chinedu I|Solomon, Ilana|Weitzel, Jeffrey|Kalady, Matthew|Blanco, Amie|T
PMID: 26248088
Journal: J Clin Oncol. 2015 Nov 1;33(31):3591-7.
Title: Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.
Author: Movahedi, Mohammad|Bishop, D Timothy|Macrae, Finlay|Mecklin, Jukka-Pekka|Moeslein, Gabriela|Olschwang, Sylviane|Eccles, Diana|Evans, D Gareth|Maher, Eamonn R|Bertario, Lucio|Bisgaard, Marie-Luise|Dunlop, Malcolm G|Ho, Judy W C|Hodgson, Shirley V|Lindblom,
PMID: 26282643
Journal: Hered Cancer Clin Pract. 2015 Aug 21;13(1):18.
Title: Next-generation sequencing for genetic testing of familial colorectal cancer syndromes.
Author: Simbolo, Michele|Mafficini, Andrea|Agostini, Marco|Pedrazzani, Corrado|Bedin, Chiara|Urso, Emanuele D|Nitti, Donato|Turri, Giona|Scardoni, Maria|Fassan, Matteo|Scarpa, Aldo
PMID: 26300997
Journal: World J Gastroenterol. 2015 Aug 21;21(31):9253-61.
Title: Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer.
Author: Carethers, John M|Stoffel, Elena M
PMID: 26309352
Journal: Orv Hetil. 2015 Sep 6;156(36):1460-71.
Title: [Occurrence, intratumoral heterogeneity, prognostic and predictive potential of microsatellite instability following surgical resection of primary colorectal carcinomas and corresponding liver metastases].
Author: Agoston, Emese Irma|Baranyai, Zsolt|Dede, Kristof|Bodoky, Gyorgy|Kulka, Janina|Bursics, Attila|Harsanyi, Laszlo|Szasz, A Marcell
PMID: 26320600
Journal: Biomed Pharmacother. 2015 Aug;74:9-16.
Title: Papillary thyroid carcinoma (PTC) in Lynch syndrome: Report of two cases and discussion on Lynch syndrome behaviour and genetics.
Author: Pelizzo, M R|Pennelli, G|Zane, M|Galuppini, F|Colletti, P M|Merante Boschin, I|Rubello, D
PMID: 26349957
Journal: J Med Life. 2015 Jul-Sep;8(3):398-403.
Title: Predictive cytogenetic biomarkers for colorectal neoplasia in medium risk patients.
Author: Ionescu, E M|Nicolaie, T|Ionescu, M A|Becheanu, G|Andrei, F|Diculescu, M|Ciocirlan, M
PMID: 26351547
Journal: Endosc Int Open. 2015 Aug;3(4):E359-62.
Title: Colon adenocarcinoma with dome-like phenotype: characteristic endoscopic ultrasonography (EUS) findings.
Author: Takagi, Wataru|Yamamoto, Katsumi|Amano, Takahiro|Sakamoto, Aisa|Otake, Yuriko|Saiki, Hirotsugu|Kondo, Hisashi|Urabe, Makiko|Takahashi, Kei|Yamamoto, Masashi|Hayashi, Shiro|Nakajima, Sachiko|Nishida, Tsutomu|Komori, Takamichi|Morita, Shunji|Adachi, Shiro|I
PMID: 26355327
Journal: Hum Pathol. 2015 Nov;46(11):1705-11.
Title: Immunohistochemistry staining for mismatch repair proteins: the endoscopic biopsy material provides useful and coherent results.
Author: Vilkin, Alex|Leibovici-Weissman, Ya'ara|Halpern, Marisa|Morgenstern, Sara|Brazovski, Eli|Gingold-Belfer, Rachel|Wasserberg, Nir|Brenner, Baruch|Niv, Yaron|Sneh-Arbib, Orly|Levi, Zohar
PMID: 26359539
Journal: Clin Epigenetics. 2015 Sep 11;7:97.
Title: Epigenetic synergy between decitabine and platinum derivatives.
Author: Qin, Taichun|Si, Jiali|Raynal, Noel J-M|Wang, Xiaodan|Gharibyan, Vazganush|Ahmed, Saira|Hu, Xin|Jin, Chunlei|Lu, Yue|Shu, Jingmin|Estecio, Marcos Rh|Jelinek, Jaroslav|Issa, Jean-Pierre J
PMID: 26366234
Journal: World J Gastroenterol. 2015 Sep 28;21(36):10461-7.
Title: Jejunitis and brown bowel syndrome with multifocal carcinogenesis of the small bowel.
Author: Raithel, Martin|Rau, Tilman T|Hagel, Alexander F|Albrecht, Heinz|de Rossi, Thomas|Kirchner, Thomas|Hahn, Eckhart G
PMID: 26420973
Journal: PLoS One. 2015 Oct 5;10(10):e0139753.
Title: Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.
Author: Carneiro da Silva, Felipe|Ferreira, Jose Roberto de Oliveira|Torrezan, Giovana Tardin|Figueiredo, Marcia Cristina Pena|Santos, Erika Maria Monteiro|Nakagawa, Wilson Toshihiko|Brianese, Rafael Canfield|Petrolini de Oliveira, Ligia|Begnani, Maria Dirlei|Agu
PMID: 26437257
Journal: Ann Acad Med Singapore. 2015 Aug;44(8):290-6.
Title: Genomics of Hereditary Colorectal Cancer: Lessons Learnt from 25 Years of the Singapore Polyposis Registry.
Author: Chew, Min Hoe|Tan, Wah Siew|Liu, Yanqun|Cheah, Peh Yean|Loi, Carol Tt|Tang, Choong Leong
PMID: 26477961
Journal: Oncotarget. 2015 Nov 17;6(36):38737-48.
Title: Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal?
Author: Maccaroni, Elena|Bracci, Raffaella|Giampieri, Riccardo|Bianchi, Francesca|Belvederesi, Laura|Brugiati, Cristiana|Pagliaretta, Silvia|Del Prete, Michela|Scartozzi, Mario|Cascinu, Stefano
PMID: 26485756
Journal: Oncotarget. 2015 Dec 8;6(39):41453-63.
Title: VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer.
Author: Schafroth, Christian|Galvan, Jose A|Centeno, Irene|Koelzer, Viktor H|Dawson, Heather E|Sokol, Lena|Rieger, Gregor|Berger, Martin D|Hadrich, Marion|Rosenberg, Robert|Nitsche, Ulrich|Schnuriger, Beat|Langer, Rupert|Inderbitzin, Daniel|Lugli, Alessandro|Zlob
PMID: 26496026
Journal: Oncotarget. 2015 Dec 22;6(41):43472-82.
Title: Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance.
Author: Scarpa, Marco|Ruffolo, Cesare|Canal, Fabio|Scarpa, Melania|Basato, Silvia|Erroi, Francesca|Fiorot, Alain|Dall'Agnese, Lucia|Pozza, Anna|Porzionato, Andrea|Castagliuolo, Ignazio|Dei Tos, Angelo P|Bassi, Nicolo|Castoro, Carlo
PMID: 26496037
Journal: Oncotarget. 2015 Dec 15;6(40):42892-904.
Title: Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.
Author: Tricarico, Rossella|Cortellino, Salvatore|Riccio, Antonio|Jagmohan-Changur, Shantie|Van der Klift, Heleen|Wijnen, Juul|Turner, David|Ventura, Andrea|Rovella, Valentina|Percesepe, Antonio|Lucci-Cordisco, Emanuela|Radice, Paolo|Bertario, Lucio|Pedroni, Moni
PMID: 26503472
Journal: Cytogenet Genome Res. 2015;146(4):261-7.
Title: Colorectal Cancers with the Uncommon Findings of KRAS Mutation and Microsatellite Instability.
Author: Zauber, Peter|Marotta, Stephen|Sabbath-Solitare, Marlene
PMID: 26523369
Journal: Case Rep Oncol. 2015 Nov 4;8(3):466-71.
Title: Signet-Ring Cell Carcinoma of the Colon: A Case Report and Review of the Literature.
Author: Park, Peter Y|Goldin, Teresa|Chang, John|Markman, Maurie|Kundranda, Madappa N
PMID: 26600781
Journal: Clin Epigenetics. 2015 Dec 21;7:131.
Title: Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.
Author: Sahnane, Nora|Magnoli, Francesca|Bernasconi, Barbara|Tibiletti, Maria Grazia|Romualdi, Chiara|Pedroni, Monica|Ponz de Leon, Maurizio|Magnani, Giulia|Reggiani-Bonetti, Luca|Bertario, Lucio|Signoroni, Stefano|Capella, Carlo|Sessa, Fausto|Furlan, Daniela
PMID: 26697123
Journal: J Gastrointest Oncol. 2015 Dec;6(6):628-37.
Title: Proficiency of DNA repair genes and microsatellite instability in operated colorectal cancer patients with clinical suspicion of lynch syndrome.
Author: de Freitas, Isabella Nicacio|de Campos, Fabio Guilherm Caserta Maryssael|Alves, Venancio Avancini Ferreira|Cavalcante, Juliana Magalhaes|Carraro, Dirce|Coudry, Renata de Almeida|Diniz, Marcio Augusto|Nahas, Sergio Carlos|Ribeiro, Ulysses Jr
PMID: 26697194
Journal: J Gastrointest Oncol. 2015 Dec;6(6):676-84.
Title: Implications of mismatch repair-deficient status on management of early stage colorectal cancer.
Author: Kawakami, Hisato|Zaanan, Aziz|Sinicrope, Frank A
PMID: 26697201
Journal: Zhonghua Zhong Liu Za Zhi. 2015 Aug;37(8):591-6.
Title: [Analysis of the relationship of DNA mismatch repair with clinicopathologic features and prognosis of colon cancer].
Author: Qin, Qiong|Ying, Jianming|Lyu, Ning|Guo, Lei|Zhi, Wenxue|Zhou, Aiping|Wang, Jinwan
PMID: 26714599
Journal: Int J Clin Exp Med. 2015 Oct 15;8(10):19652-61. eCollection 2015.
Title: Human mutL homolog 1 expression characteristic and prognostic effect on patients with sporadic colorectal cancer.
Author: Pu, Chibin|Ren, Weiguo|Sun, Zhenqiang|Yu, Xianbo|Yuan, Wei|Huang, Mingyu|Shen, Shourong|Wang, Xiaoyan
PMID: 26770629
Journal: Gan To Kagaku Ryoho. 2015 Nov;42(12):2215-7.
Title: [A Case of Serrated Polyposis Syndrome with Early Colon Cancer].
Author: Suzuki, Okihide|Chika, Noriyasu|Tachikawa, Tetsuhiko|Aoyagi, Nobuhiko|Eguchi, Hidetaka|Kumamoto, Kensuke|Mochiki, Erito|Miura, Ichiro|Yao, Takashi|Ishida, Hideyuki
PMID: 26805315
Journal: Genes Cancer. 2015 Nov;6(11-12):445-51.
Title: Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.
Author: Win, Aung Ko|Clendenning, Mark|Crawford, William|Rosty, Christophe|Preston, Susan G|Southey, Melissa C|Parry, Susan|Giles, Graham G|Macrae, Finlay A|Winship, Ingrid M|Baron, John A|Hopper, John L|Jenkins, Mark A|Buchanan, Daniel D
PMID: 26807197
Journal: Int J Clin Exp Med. 2015 Nov 15;8(11):20988-1000. eCollection 2015.
Title: Immunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency.
Author: Yuan, Lin|Chi, Yayun|Chen, Weixiang|Chen, Xiaochen|Wei, Ping|Sheng, Weiqi|Zhou, Xiaoyan|Shi, Daren
PMID: 26885030
Journal: Genet Med. 2016 Jan;18(1):13-9.
Title: PMS2 monoallelic mutation carriers: the known unknown.
Author: Goodenberger, McKinsey L|Thomas, Brittany C|Riegert-Johnson, Douglas|Boland, C Richard|Plon, Sharon E|Clendenning, Mark|Win, Aung Ko|Senter, Leigha|Lipkin, Steven M|Stadler, Zsofia K|Macrae, Finlay A|Lynch, Henry T|Weitzel, Jeffrey N|de la Chapelle, Alber
PMID: 25856668
Journal: Cancer Res Treat. 2016 Jan;48(1):208-15.
Title: p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author: Kim, Se Hyun|Park, Kyu Hyun|Shin, Sang Joon|Lee, Kang Young|Kim, Tae Il|Kim, Nam Kyu|Rha, Sun Young|Roh, Jae Kyung|Ahn, Joong Bae
PMID: 25943321
Journal: Histopathology. 2016 Mar;68(4):578-87.
Title: Serrated tubulovillous adenoma of the large intestine.
Author: Bettington, Mark|Walker, Neal|Rosty, Christophe|Brown, Ian|Clouston, Andrew|McKeone, Diane|Pearson, Sally-Ann|Klein, Kerenaftali|Leggett, Barbara|Whitehall, Vicki
PMID: 26212352
Journal: QJM. 2016 Mar;109(3):151-8.
Title: Lynch syndrome in the 21st century: clinical perspectives.
Author: Tiwari, A K|Roy, H K|Lynch, H T
PMID: 26224055
Journal: Surg Today. 2016 Jun;46(6):713-20.
Title: Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population.
Author: Kumamoto, Kensuke|Ishida, Hideyuki|Suzuki, Okihide|Tajima, Yusuke|Chika, Noriyasu|Kuwabara, Koki|Ishibashi, Keiichiro|Saito, Katsuharu|Nagata, Koji|Eguchi, Hidetaka|Tamaru, Junichi|Iwama, Takeo
PMID: 26249337
Journal: Eur J Obstet Gynecol Reprod Biol. 2016 Apr;199:208-12.
Title: Women with double primary cancers of the colorectum and endometrium: do they have Lynch syndrome?
Author: Song, Taejong|Kim, Min Kyu|Lee, Yoo-Young|Choi, Chel Hun|Kim, Tae-Joong|Lee, Jeong-Won|Bae, Duk-Soo|Kim, Byoung-Gie
PMID: 26298861
Journal: Tumour Biol. 2016 Mar;37(3):3145-53.
Title: ROBO1 deletion as a novel germline alteration in breast and colorectal cancer patients.
Author: Villacis, Rolando A R|Abreu, Francine B|Miranda, Priscila M|Domingues, Maria A C|Carraro, Dirce M|Santos, Erika M M|Andrade, Victor P|Rossi, Benedito M|Achatz, Maria I|Rogatto, Silvia R
PMID: 26427657
Journal: Int J Cancer. 2016 Mar 15;138(6):1472-81.
Title: The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.
Author: Renaud, Florence|Mariette, Christophe|Vincent, Audrey|Wacrenier, Agnes|Maunoury, Vincent|Leclerc, Julie|Coppin, Lucie|Crepin, Michel|Van Seuningen, Isabelle|Leteurtre, Emmanuelle|Buisine, Marie-Pierre
PMID: 26476272
Journal: Int J Cancer. 2016 Apr 1;138(7):1634-44.
Title: Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway.
Author: Sakai, Eiji|Fukuyo, Masaki|Ohata, Ken|Matsusaka, Keisuke|Doi, Noriteru|Mano, Yasunobu|Takane, Kiyoko|Abe, Hiroyuki|Yagi, Koichi|Matsuhashi, Nobuyuki|Fukushima, Junichi|Fukayama, Masashi|Akagi, Kiwamu|Aburatani, Hiroyuki|Nakajima, Atsushi|Kaneda, Atsushi
PMID: 26510091
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):68-75.
Title: Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors.
Author: Levine, A Joan|Phipps, Amanda I|Baron, John A|Buchanan, Daniel D|Ahnen, Dennis J|Cohen, Stacey A|Lindor, Noralane M|Newcomb, Polly A|Rosty, Christophe|Haile, Robert W|Laird, Peter W|Weisenberger, Daniel J
PMID: 26512054
Journal: Pediatr Blood Cancer. 2016 Mar;63(3):418-27.
Title: Constitutional Mismatch Repair Deficiency in Israel: High Proportion of Founder Mutations in MMR Genes and Consanguinity.
Author: Baris, Hagit N|Barnes-Kedar, Inbal|Toledano, Helen|Halpern, Marisa|Hershkovitz, Dov|Lossos, Alexander|Lerer, Israela|Peretz, Tamar|Kariv, Revital|Cohen, Shlomi|Half, Elizabeth E|Magal, Nurit|Drasinover, Valerie|Wimmer, Katharina|Goldberg, Yael|Bercovich,
PMID: 26544533
Journal: Exp Mol Pathol. 2016 Feb;100(1):59-66.
Title: CDX2 downregulation is associated with poor differentiation and MMR deficiency in colon cancer.
Author: Olsen, J|Eiholm, S|Kirkeby, L T|Espersen, M L M|Jess, P|Gogenur, I|Olsen, J|Troelsen, J T
PMID: 26551082
Journal: Head Neck Pathol. 2016 Sep;10(3):354-61.
Title: Parotid Sebaceous Carcinoma in Patient with Muir Torre Syndrome, Caused by MSH2 Mutation.
Author: Neelakantan, Iyer Vishwas|Di Palma, Silvana|Smith, C E T|McCoombe, A
PMID: 26577210
Journal: J Natl Cancer Inst. 2015 Nov 18;108(2). pii: djv308.
Title: Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer.
Author: Kastrinos, Fay|Ojha, Rohit P|Leenen, Celine|Alvero, Carmelita|Mercado, Rowena C|Balmana, Judith|Valenzuela, Irene|Balaguer, Francesc|Green, Roger|Lindor, Noralane M|Thibodeau, Stephen N|Newcomb, Polly|Win, Aung Ko|Jenkins, Mark|Buchanan, Daniel D|Bertario
PMID: 26582061
Journal: Int J Cancer. 2016 Apr 15;138(8):1928-35.
Title: Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes.
Author: Villacis, Rolando A R|Miranda, Priscila M|Gomy, Israel|Santos, Erika M M|Carraro, Dirce M|Achatz, Maria I|Rossi, Benedito M|Rogatto, Silvia R
PMID: 26620301
Journal: Genes Chromosomes Cancer. 2016 Mar;55(3):268-77.
Title: Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies.
Author: Jesinghaus, Moritz|Pfarr, Nicole|Kloor, Matthias|Endris, Volker|Tavernar, Luca|Muckenhuber, Alexander|von Knebel Doeberitz, Magnus|Penzel, Roland|Weichert, Wilko|Stenzinger, Albrecht
PMID: 26650777
Journal: Fam Cancer. 2016 Apr;15(2):253-60.
Title: Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasis.
Author: Haraldsdottir, Sigurdis|Roth, Rachel|Pearlman, Rachel|Hampel, Heather|Arnold, Christina A|Frankel, Wendy L
PMID: 26666765
Journal: Genet Med. 2016 Aug;18(8):823-32.
Title: Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
Author: Susswein, Lisa R|Marshall, Megan L|Nusbaum, Rachel|Vogel Postula, Kristen J|Weissman, Scott M|Yackowski, Lauren|Vaccari, Erica M|Bissonnette, Jeffrey|Booker, Jessica K|Cremona, M Laura|Gibellini, Federica|Murphy, Patricia D|Pineda-Alvarez, Daniel E|Pollev
PMID: 26681312
Journal: Mol Cell Biochem. 2016 Jan;412(1-2):297-305.
Title: Interdependence of DNA mismatch repair proteins MLH1 and MSH2 in apoptosis in human colorectal carcinoma cell lines.
Author: Hassen, Samar|Ali, Akhtar A|Kilaparty, Surya P|Al-Anbaky, Qudes A|Majeed, Waqar|Boman, Bruce M|Fields, Jeremy Z|Ali, Nawab
PMID: 26728996
Journal: DNA Repair (Amst). 2016 Feb;38:155-62.
Title: Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations.
Author: Sijmons, Rolf H|Hofstra, Robert M W
PMID: 26746812
Journal: Gastroenterology. 2016 Apr;150(4):931-43.
Title: Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Author: Robles, Ana I|Traverso, Giovanni|Zhang, Ming|Roberts, Nicholas J|Khan, Mohammed A|Joseph, Christine|Lauwers, Gregory Y|Selaru, Florin M|Popoli, Maria|Pittman, Meredith E|Ke, Xiquan|Hruban, Ralph H|Meltzer, Stephen J|Kinzler, Kenneth W|Vogelstein, Bert|Har
PMID: 26764183
Journal: Gastroenterol Hepatol. 2016 Oct;39(8):500-7.
Title: [Prevalence of altered mismatch repair protein nuclear expression detected by immunohistochemistry on adenomas with high-grade dysplasia and features associated with this risk in a population-based study].
Author: Basterra, Marta|Gomez, Marta|Mercado, Maria Del Rosario|Irisarri, Rebeca|Amorena, Edurne|Arrospide, Arantzazu|Montes, Marta|Aisa, Gregorio|Cambra, Koldo Inaki|Urman, Jesus
PMID: 26790715
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Jan;19(1):75-9.
Title: [Expression difference of DNA mismatch repair gene hMLH1 and hMSH2 between schistosomiasis-associated colorectal cancer and sporadic colorectal cancer].
Author: Chen, Yinbo|Liu, Zhuo|Qian, Jun|Feng, Haiyang|Li, Dechuan|Fan, Yongtian
PMID: 26797844
Journal: Am J Surg Pathol. 2016 May;40(5):656-63.
Title: Mismatch Repair Protein Expression in Clear Cell Carcinoma of the Ovary: Incidence and Morphologic Associations in 109 Cases.
Author: Bennett, Jennifer A|Morales-Oyarvide, Vicente|Campbell, Sharon|Longacre, Teri A|Oliva, Esther
PMID: 26813747
Journal: Medicine (Baltimore). 2016 Jan;95(3):e2582.
Title: Mismatch Repair Gene Expression as a Predictor of Tumor Responses in Patients With Rectal Cancer Treated With Preoperative Chemoradiation.
Author: Huh, Jung Wook|Kim, Hee Cheol|Kim, Seok Hyung|Park, Yoon Ah|Cho, Yong Beom|Yun, Seong Hyeon|Lee, Woo Yong|Park, Hee Chul|Choi, Doo Ho|Park, Joon Oh|Park, Young Suk|Chun, Ho-Kyung
PMID: 26817916
Journal: Hum Pathol. 2016 Mar;49:1-9.
Title: Importance of universal mismatch repair protein immunohistochemistry in patients with sebaceous neoplasia as an initial screening tool for Muir-Torre syndrome.
Author: Jessup, Chad J|Redston, Mark|Tilton, Erin|Reimann, Julie D R
PMID: 26826402
Journal: Mol Cell Biochem. 2016 Mar;414(1-2):13-22.
Title: GADD45alpha modulates curcumin sensitivity through c-Abl- and JNK-dependent signaling pathways in a mismatch repair-dependent manner.
Author: Naick, Hemanth|Jin, Shunqian|Baskaran, R
PMID: 26833194
Journal: Fam Cancer. 2016 Oct;15(4):553-62.
Title: Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies.
Author: Kohda, Masakazu|Kumamoto, Kensuke|Eguchi, Hidetaka|Hirata, Tomoko|Tada, Yuhki|Tanakaya, Kohji|Akagi, Kiwamu|Takenoshita, Seiichi|Iwama, Takeo|Ishida, Hideyuki|Okazaki, Yasushi
PMID: 26837502
Journal: Am J Surg Pathol. 2016 Jun;40(6):770-6.
Title: Isolated Loss of PMS2 Immunohistochemical Expression is Frequently Caused by Heterogenous MLH1 Promoter Hypermethylation in Lynch Syndrome Screening for Endometrial Cancer Patients.
Author: Kato, Aya|Sato, Naoki|Sugawara, Tae|Takahashi, Kazue|Kito, Masahiko|Makino, Kenichi|Sato, Toshiharu|Shimizu, Dai|Shirasawa, Hiromistu|Miura, Hiroshi|Sato, Wataru|Kumazawa, Yukiyo|Sato, Akira|Kumagai, Jin|Terada, Yukihiro
PMID: 26848797
Journal: Oncotarget. 2016 Mar 1;7(9):10322-31.
Title: Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC.
Author: Scarpa, Marco|Scarpa, Melania|Castagliuolo, Ignazio|Erroi, Francesca|Kotsafti, Andromachi|Basato, Silvia|Brun, Paola|D'Inca, Renata|Rugge, Massimo|Angriman, Imerio|Castoro, Carlo
PMID: 26862732
Journal: Genet Med. 2016 Sep;18(9):863-8.
Title: Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses.
Author: Haraldsdottir, Sigurdis|Hampel, Heather|Wu, Christina|Weng, Daniel Y|Shields, Peter G|Frankel, Wendy L|Pan, Xueliang|de la Chapelle, Albert|Goldberg, Richard M|Bekaii-Saab, Tanios
PMID: 26866578
Journal: Fam Cancer. 2016 Jul;15(3):385-93.
Title: Update on Lynch syndrome genomics.
Author: Peltomaki, Paivi
PMID: 26873718
Journal: Fam Cancer. 2016 Jul;15(3):405-12.
Title: High microsatellite instability (MSI-H) colorectal carcinoma: a brief review of predictive biomarkers in the era of personalized medicine.
Author: Gatalica, Zoran|Vranic, Semir|Xiu, Joanne|Swensen, Jeffrey|Reddy, Sandeep
PMID: 26875156
Journal: Oncotarget. 2016 Mar 22;7(12):14095-111.
Title: Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway.
Author: Kim, Jung Ho|Bae, Jeong Mo|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 26883113
Journal: BMC Cancer. 2016 Feb 17;16:113.
Title: Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients.
Author: Savio, Andrea J|Daftary, Darshana|Dicks, Elizabeth|Buchanan, Daniel D|Parfrey, Patrick S|Young, Joanne P|Weisenberger, Daniel|Green, Roger C|Gallinger, Steven|McLaughlin, John R|Knight, Julia A|Bapat, Bharati
PMID: 26884349
Journal: Korean J Pediatr. 2016 Jan;59(1):40-2.
Title: Early onset of colorectal cancer in a 13-year-old girl with Lynch syndrome.
Author: Ahn, Do Hee|Rho, Jung Hee|Tchah, Hann|Jeon, In-Sang
PMID: 26893603
Journal: BMJ Open. 2016 Feb 19;6(2):e010293.
Title: Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
Author: Rosty, Christophe|Clendenning, Mark|Walsh, Michael D|Eriksen, Stine V|Southey, Melissa C|Winship, Ingrid M|Macrae, Finlay A|Boussioutas, Alex|Poplawski, Nicola K|Parry, Susan|Arnold, Julie|Young, Joanne P|Casey, Graham|Haile, Robert W|Gallinger, Steven|Le
PMID: 26895986
Journal: Clin Gastroenterol Hepatol. 2016 Jul;14(7):1056-9.
Title: Sessile Serrated Polyps are Precursors of Colon Carcinomas With Deficient DNA Mismatch Repair.
Author: Sweetser, Seth|Jones, Andrea|Smyrk, Thomas C|Sinicrope, Frank A
PMID: 26898652
Journal: World J Gastroenterol. 2016 Feb 21;22(7):2314-25.
Title: Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients.
Author: Chang, Yuli Christine|Chang, Jan-Gowth|Liu, Ta-Chih|Lin, Chien-Yu|Yang, Shu-Fen|Ho, Cheng-Mao|Chen, William Tzu-Liang|Chang, Ya-Sian
PMID: 26900293
Journal: Meta Gene. 2015 Dec 24;7:95-104.
Title: Copy number variants associated with 18p11.32, DCC and the promoter 1B region of APC in colorectal polyposis patients.
Author: Masson, Amy L|Talseth-Palmer, Bente A|Evans, Tiffany-Jane|McElduff, Patrick|Spigelman, Allan D|Hannan, Garry N|Scott, Rodney J
PMID: 26909336
Journal: Gut. 2016 Jul;65(7):1227-8.
Title: Functional annotation of colorectal cancer susceptibility loci identifies MLH1 rs1800734 associated with MSI patients.
Author: Ma, Gaoxiang|Ge, Yuqiu|Gu, Dongying|Du, Mulong|Chu, Haiyan|Chen, Jinfei|Zhang, Zhengdong|Wang, Meilin
PMID: 26911399
Journal: Case Rep Oncol. 2016 Feb 4;9(1):95-9.
Title: Muir-Torre Syndrome Presenting as Sebaceous Adenocarcinoma and Invasive MSH6-Positive Colorectal Adenocarcinoma.
Author: Tulpule, Sunil|Ibrahim, Hiyam|Osman, Mohamed|Zafar, Shoaib|Kanta, Romana|Shypula, Gregory|Islam, Mohammed A|Sen, Shuvendu|Yousif, Abdalla
PMID: 26933426
Journal: Genet Med. 2016 Oct;18(10):966-73.
Title: Cost-effectiveness of routine screening for Lynch syndrome in colorectal cancer patients up to 70 years of age.
Author: Leenen, Celine H M|Goverde, Anne|de Bekker-Grob, Esther W|Wagner, Anja|van Lier, Margot G F|Spaander, Manon C W|Bruno, Marco J|Tops, Carli M|van den Ouweland, Ans M W|Dubbink, Hendrikus J|Kuipers, Ernst J|Dinjens, Winand N M|van Leerdam, Monique E|Steyerb
PMID: 26938782
Journal: Oncotarget. 2016 Jun 14;7(24):37331-37346.
Title: The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer.
Author: Gao, Dan|Herman, James G|Guo, Mingzhou
PMID: 26967246
Journal: Dig Liver Dis. 2016 Jun;48(6):681-3.
Title: Absence of IDH mutation in colorectal cancers with microsatellite instability.
Author: Tougeron, David|Guilloteau, Karline|Karayan-Tapon, Lucie
PMID: 26987944
Journal: Cancer Prev Res (Phila). 2016 Jun;9(6):456-65.
Title: Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.
Author: Kanth, Priyanka|Bronner, Mary P|Boucher, Kenneth M|Burt, Randall W|Neklason, Deborah W|Hagedorn, Curt H|Delker, Don A
PMID: 27026680
Journal: Fam Cancer. 2016 Jul;15(3):395-403.
Title: Recent discoveries in the molecular genetics of Lynch syndrome.
Author: Boland, C Richard
PMID: 27038793
Journal: Clin Gastroenterol Hepatol. 2016 Aug;14(8):1163-71.
Title: Colorectal Tumors From Different Racial and Ethnic Minorities Have Similar Rates of Mismatch Repair Deficiency.
Author: Berera, Shivali|Koru-Sengul, Tulay|Miao, Feng|Carrasquillo, Olveen|Nadji, Mehrdad|Zhang, Yaxia|Hosein, Peter J|McCauley, Jacob L|Abreu, Maria T|Sussman, Daniel A
PMID: 27046481
Journal: Int J Epidemiol. 2016 Jun;45(3):940-53.
Title: Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome.
Author: Chau, Rowena|Dashti, Seyedeh Ghazaleh|Ait Ouakrim, Driss|Buchanan, Daniel D|Clendenning, Mark|Rosty, Christophe|Winship, Ingrid M|Young, Joanne P|Giles, Graham G|Macrae, Finlay A|Boussioutas, Alex|Parry, Susan|Figueiredo, Jane C|Levine, A Joan|Ahnen, Denn
PMID: 27063605
Journal: Gan To Kagaku Ryoho. 2016 Mar;43(3):294-9.
Title: [Pathological Diagnosis and Its Molecular Basis in Colorectal Cancer].
Author: Sugai, Tamotsu|Habano, Wataru
PMID: 27067845
Journal: Anticancer Res. 2016 Apr;36(4):1985-9.
Title: Causes of Cancer Death Among First-Degree Relatives in Japanese Families with Lynch Syndrome.
Author: Tanakaya, Kohji|Yamaguchi, Tatsuro|Ishikawa, Hideki|Hinoi, Takao|Furukawa, Yoichi|Hirata, Keiji|Saida, Yoshihisa|Shimokawa, Mototsugu|Arai, Masami|Matsubara, Nagahide|Tomita, Naohiro|Tamura, Kazuo|Sugano, Kokichi|Ishioka, Chikashi|Yoshida, Teruhiko|Ishida
PMID: 27069191
Journal: Zhonghua Zhong Liu Za Zhi. 2016 Apr;38(4):283-8.
Title: [Relationship between microsatellite instability and hepatocyte growth factor expression and their prognostic significance in colorectal cancer].
Author: Yang, G|Zheng, H X|Wu, L N|Wan, H L|Li, N|Yang, G C|Liang, J F
PMID: 27087375
Journal: Cancer Biol Ther. 2016 Jul 2;17(7):760-8.
Title: Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.
Author: Suzuki, Satoshi|Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Hamaya, Yasushi|Miyajima, Hiroaki|Kanaoka, Shigeru|Sugimoto, Ken|Carethers, John M
PMID: 27115207
Journal: Oncotarget. 2016 Jun 21;7(25):37566-37580.
Title: NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing.
Author: Chang, Pi-Yueh|Chen, Jinn-Shiun|Chang, Nai-Chung|Chang, Shih-Cheng|Wang, Mei-Chia|Tsai, Shu-Hui|Wen, Ying-Hao|Tsai, Wen-Sy|Chan, Err-Cheng|Lu, Jang-Jih
PMID: 27121310
Journal: Swiss Med Wkly. 2016 May 6;146:w14315.
Title: Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.
Author: Zumstein, Valentin|Vinzens, Fabrizio|Zettl, Andreas|Heinimann, Karl|Koeberle, Dieter|von Flue, Markus|Bolli, Martin
PMID: 27152634
Journal: Genet Mol Res. 2016 Apr 26;15(2). pii: gmr7689.
Title: Molecular analysis of MLH1 variants in Chinese sporadic colorectal cancer patients.
Author: Peng, H X|Xu, X|Yang, R|Chu, Y M|Yang, D M|Xu, Y|Zhou, F L|Ma, W Z|Zhang, X J|Guan, M|Yang, Z H|Jin, Z D
PMID: 27173243
Journal: Virchows Arch. 2016 Aug;469(2):135-44.
Title: Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Author: Boissiere-Michot, Florence|Frugier, Helene|Ho-Pun-Cheung, Alexandre|Lopez-Crapez, Evelyne|Duffour, Jacqueline|Bibeau, Frederic
PMID: 27220764
Journal: Carcinogenesis. 2016 Aug;37(8):751-8.
Title: Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC).
Author: Xicola, Rosa M|Bontu, Sneha|Doyle, Brian J|Rawson, Jamie|Garre, Pilar|Lee, Esther|de la Hoya, Miguel|Bessa, Xavier|Clofent, Joan|Bujanda, Luis|Balaguer, Francesc|Castellvi-Bel, Sergi|Alenda, Cristina|Jover, Rodrigo|Ruiz-Ponte, Clara|Syngal, Sapna|Andreu,
PMID: 27234654
Journal: Asian Pac J Cancer Prev. 2016;17(5):2587-92.
Title: Sporadic Early Onset Colorectal Cancer in Pakistan: a Case- Control Analysis of Microsatellite Instability.
Author: Siddique, Sabeehuddin|Tariq, Kanwal|Rafiq, Sobia|Raheem, Ahmed|Ahmed, Rashida|Shabbir-Moosajee, Munira|Ghias, Kulsoom
PMID: 27268635
Journal: Medicina (B Aires). 2016;76(3):180-2.
Title: [Founder mutation in Lynch syndrome].
Author: Cajal, Andrea R|Pinero, Tamara A|Verzura, Alicia|Santino, Juan Pablo|Solano, Angela R|Kalfayan, Pablo G|Ferro, Alejandra|Vaccaro, Carlos
PMID: 27295708
Journal: Klin Onkol. 2016;29(3):180-6.
Title: [Lynch Syndrome - the Pathologist's Diagnosis].
Author: Dusek, M|Hadravsky, L|Cerna, K|Stehlik, J|Svajdler, M|Kokoskova, B|Dubova, M|Michal, M|Daum, O
PMID: 27296402
Journal: PLoS One. 2016 Jun 14;11(6):e0157381.
Title: Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.
Author: Jansen, Anne M L|Geilenkirchen, Marije A|van Wezel, Tom|Jagmohan-Changur, Shantie C|Ruano, Dina|van der Klift, Heleen M|van den Akker, Brendy E W M|Laros, Jeroen F J|van Galen, Michiel|Wagner, Anja|Letteboer, Tom G W|Gomez-Garcia, Encarna B|Tops, Carli M
PMID: 27300758
Journal: Gastroenterology. 2016 Sep;151(3):440-447.e1.
Title: Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes.
Author: Cohen, Stacey A|Turner, Emily H|Beightol, Mallory B|Jacobson, Angela|Gooley, Ted A|Salipante, Stephen J|Haraldsdottir, Sigurdis|Smith, Christina|Scroggins, Sheena|Tait, Jonathan F|Grady, William M|Lin, Edward H|Cohn, David E|Goodfellow, Paul J|Arnold, Mar
PMID: 27302833
Journal: Oncotarget. 2016 Jul 19;7(29):46158-46172.
Title: Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism.
Author: Wei, Zhiliang|Cao, Shougen|Liu, Shanglong|Yao, Zengwu|Sun, Teng|Li, Yi|Li, Jiante|Zhang, Dongfeng|Zhou, Yanbing
PMID: 27323816
Journal: Biochim Biophys Acta. 2016 Aug;1866(1):106-20.
Title: DNA methylation based biomarkers in colorectal cancer: A systematic review.
Author: Lam, Kevin|Pan, Kathy|Linnekamp, Janneke Fiona|Medema, Jan Paul|Kandimalla, Raju
PMID: 27385266
Journal: Int J Surg Pathol. 2016 Oct;24(7):653-5.
Title: Primary Colon Adenosquamous Carcinoma in a Patient With Lynch Syndrome: A New Histologic Subtype Associated With Microsatellite Instability?
Author: Duncan, Virginia E|Harada, Shuko|Stevens, Todd M
PMID: 27422471
Journal: Am J Surg Pathol. 2016 Oct;40(10):1390-9.
Title: MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas.
Author: Farchoukh, Lama|Kuan, Shih-Fan|Dudley, Beth|Brand, Randall|Nikiforova, Marina|Pai, Reetesh K
PMID: 27438990
Journal: Oncol Lett. 2016 Aug;12(2):1602-1604.
Title: Small bowel adenocarcinoma in Lynch syndrome: A case report.
Author: Sun, Ke-Kang|Liu, Gang|Shen, Xiaojun|Wu, Xiaoyang
PMID: 27446478
Journal: J Natl Compr Canc Netw. 2016 Aug;14(8):1010-30.
Title: Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.
Author: Provenzale, Dawn|Gupta, Samir|Ahnen, Dennis J|Bray, Travis|Cannon, Jamie A|Cooper, Gregory|David, Donald S|Early, Dayna S|Erwin, Deborah|Ford, James M|Giardiello, Francis M|Grady, William|Halverson, Amy L|Hamilton, Stanley R|Hampel, Heather|Ismail, Mohamm
PMID: 27496117
Journal: J Pathol Clin Res. 2016 Apr 22;2(3):127-37.
Title: The molecular characteristics of colonic neoplasms in serrated polyposis: a systematic review and meta-analysis.
Author: He, Emily Y|Wyld, Lucy|Sloane, Mathew A|Canfell, Karen|Ward, Robyn L
PMID: 27499922
Journal: Arch Gynecol Obstet. 2016 Nov;294(6):1299-1303.
Title: Prevalence of Lynch syndrome in unselected patients with endometrial or ovarian cancer.
Author: Kast, Karin|Dobberschutz, Catharina|Sadowski, Carolin Eva|Pistorius, Steffen|Wimberger, Pauline
PMID: 27535758
Journal: J Pediatr Surg. 2016 Nov;51(11):1812-1817.
Title: Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients.
Author: Khan, Sajid A|Morris, Melinda|Idrees, Kamran|Gimbel, Mark I|Rosenberg, Shoshana|Zeng, Zhaoshi|Li, Fangyong|Gan, Geliang|Shia, Jinru|LaQuaglia, Michael P|Paty, Philip B
PMID: 27558481
Journal: Cancer Sci. 2016 Nov;107(11):1677-1686.
Title: Germline PMS2 mutation screened by mismatch repair protein immunohistochemistry of colorectal cancer in Japan.
Author: Sugano, Kokichi|Nakajima, Takeshi|Sekine, Shigeki|Taniguchi, Hirokazu|Saito, Shinya|Takahashi, Masahiro|Ushiama, Mineko|Sakamoto, Hiromi|Yoshida, Teruhiko
PMID: 27589204
Journal: Pathologe. 2016 Nov;37(Suppl 2):186-190.
Title: [Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
Author: Rau, T
PMID: 27638535
Journal: Pan Afr Med J. 2016 Jun 14;24:142.
Title: [Lynch syndrome: case report and review of the literature].
Author: Bouguenouch, Laila|Samri, Imane|Belhassan, Khadija|Sayel, Hanane|Abbassi, Meriame|Bennis, Sanae|Benajah, Dafr Allah|Ibrahimi, Adil|Amarti, Afaf|Ouldim, Karim
PMID: 27642480
Journal: Genet Mol Res. 2016 Aug 19;15(3). pii: gmr8388.
Title: Association between expression of DNA mismatch repair genes and clinical features and prognosis of patients with radical resection of colon cancer.
Author: Wang, J B|Ma, D L|Li, J Y|Sun, Q D|Liu, Y E
PMID: 27706583
Journal: Genes (Basel). 2016 Oct 14;7(10). pii: genes7100086.
Title: Methylation Analysis of DNA Mismatch Repair Genes Using DNA Derived from the Peripheral Blood of Patients with Endometrial Cancer: Epimutation in Endometrial Carcinogenesis.
Author: Takeda, Takashi|Banno, Kouji|Yanokura, Megumi|Adachi, Masataka|Iijima, Moito|Kunitomi, Haruko|Nakamura, Kanako|Iida, Miho|Nogami, Yuya|Umene, Kiyoko|Masuda, Kenta|Kobayashi, Yusuke|Yamagami, Wataru|Hirasawa, Akira|Tominaga, Eiichiro|Susumu, Nobuyuki|Aoki,
PMID: 27754426
Journal: BMC Bioinformatics. 2016 Oct 22;17(1):430.
Title: Subcellular protein expression models for microsatellite instability in colorectal adenocarcinoma tissue images.
Author: Kovacheva, Violeta N|Rajpoot, Nasir M
PMID: 27770786
Journal: Gynecol Oncol. 2016 Dec;143(3):453-459.
Title: Cost-effectiveness of routine screening for Lynch syndrome in endometrial cancer patients up to 70years of age.
Author: Goverde, Anne|Spaander, Manon Cw|van Doorn, Helena C|Dubbink, Hendrikus J|van den Ouweland, Ans Mw|Tops, Carli M|Kooi, Sjarlot G|de Waard, Judith|Hoedemaeker, Robert F|Bruno, Marco J|Hofstra, Robert Mw|de Bekker-Grob, Esther W|Dinjens, Winand Nm|Steyerber
PMID: 27789085
Journal: Cancer Treat Rev. 2016 Dec;51:19-26.
Title: The evolving role of microsatellite instability in colorectal cancer: A review.
Author: Gelsomino, Fabio|Barbolini, Monica|Spallanzani, Andrea|Pugliese, Giuseppe|Cascinu, Stefano
PMID: 27838401
Journal: Oncol Lett. 2016 Nov;12(5):4035-4040.
Title: A promoter polymorphism in the hMLH1 gene (-93G/A) associated with sporadic colorectal cancer.
Author: Zhang, Li-Li|Tang, Xue-Jun|Wang, Xiao-Yun|Zhu, Ying-Wei|Peng, Xiao-Bin|Gong, Lei
PMID: 27895767
Journal: PLoS One. 2016 Dec 1;11(12):e0167354.
Title: TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study.
Author: Kamiza, Abram Bunya|Hsieh, Ling-Ling|Tang, Reiping|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|You, Jeng-Fu|Wang, Wen-Chang|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 27907203
Journal: BMC Med Genet. 2016 Dec 9;17(1):94.
Title: Pseudomyxoma peritonei of a mature ovarian teratoma caused by mismatch repair deficiency in a patient with Lynch syndrome: a case report.
Author: Gohda, Yoshimasa|Noguchi, Rei|Horie, Tomoko|Igari, Toru|Nakamura, Harumi|Ohta, Yasunori|Yamaguchi, Kiyoshi|Ikenoue, Tsuneo|Hatakeyama, Seira|Yusa, Nozomi|Furukawa, Yoichi|Yano, Hideaki
PMID: 27938333
Journal: Front Oncol. 2016 Nov 29;6:252.
Title: Colorectal Choriocarcinoma in a Patient with Probable Lynch Syndrome.
Author: Koelzer, Viktor H|Steuer, Karl|Gross, Ulrike Camenisch|Zimmermann, Dieter|Paasinen-Sohns, Aino|Mertz, Kirsten D|Cathomas, Gieri
PMID: 27965933
Journal: Clin Transl Gastroenterol. 2016 Dec 15;7(12):e208.
Title: DNA Methylation Identifies Loci Distinguishing Hereditary Nonpolyposis Colorectal Cancer Without Germ-Line MLH1/MSH2 Mutation from Sporadic Colorectal Cancer.
Author: Chen, Chung-Hsing|Sheng Jiang, Shih|Hsieh, Ling-Ling|Tang, Reiping|Hsiung, Chao A|Tsai, Hui-Ju|Chang, I-Shou
PMID: 27977020
Journal: Onco Targets Ther. 2016 Dec 8;9:7415-7424.
Title: Prediction of biological behavior and prognosis of colorectal cancer patients by tumor MSI/MMR in the Chinese population.
Author: Yan, Wen-Yue|Hu, Jing|Xie, Li|Cheng, Lei|Yang, Mi|Li, Li|Shi, Jiong|Liu, Bao-Rui|Qian, Xiao-Ping
PMID: 27994472
Journal: Acta Med Port. 2016 Oct;29(10):587-596.
Title: Phenotypic Heterogeneity by Germline Mismatch Repair Gene Defect in Lynch Syndrome Patients.
Author: Hernani-Eusebio, Jorge|Barbosa, Elisabete
PMID: 28103454
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1693-1695.
Title: [Evaluation of BRAF V600E Mutations in High-Level Microsatellite Instability(MSI-H)Colon Cancer - Comparison Between Genetic Testing and Immunohistochemical Staining].
Author: Sakimoto, Takehiko|Chika, Noriyasu|Suzuki, Okihide|Ishibashi, Keiichiro|Tachikawa, Tetsuhiko|Akagi, Kiwamu|Eguchi, Hidetaka|Okazaki, Yasushi|Ishida, Hideyuki
PMID: 28133101
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1711-1714.
Title: [Characteristics and Outcomes of Treatment in Patients with Stage IV Colorectal Cancer with Mismatch Repair Deficiency].
Author: Ishibashi, Keiichiro|Chika, Noriyasu|Suzuki, Okihide|Ito, Tetsuya|Amano, Kunihiko|Kumamoto, Kensuke|Fukuchi, Minoru|Kumagai, Youichi|Mochiki, Erito|Ishida, Hideyuki
PMID: 28133107
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1818-1820.
Title: [Lynch Syndrome Caused by Germline Alteration of MLH1 in a Young Patient Who Developed Colon and Endometrial Cancer - A Case Report].
Author: Yamamoto, Azusa|Suzuki, Okihide|Chika, Noriyasu|Ito, Tetsuya|Tajima, Yusuke|Kumamoto, Kensuke|Eguchi, Hidetaka|Kumagai, Youichi|Ishibashi, Keiichiro|Mochiki, Erito|Okazaki, Yasushi|Ishida, Hideyuki
PMID: 28133142
Journal: Pathologica. 2016 Sep;108(3):104-109.
Title: Immunohistochemical evaluation of mismatch repair proteins in colorectal carcinoma: the AIFEG/GIPAD proposal.
Author: Remo, A|Fassan, M|Lanza, G
PMID: 28195261
Journal: Indian J Cancer. 2016 Oct-Dec;53(4):513-517.
Title: Microsatellite instability in stage II colorectal cancer: An Indian perspective.
Author: Dubey, A P|Vishwanath, S|Nikhil, P|Rathore, A|Pathak, A
PMID: 28485341
Journal: ACS Omega. 2016 Dec 31;1(6):1164-1172.
Title: Inhibition of DNA Methylation at the MLH1 Promoter Region Using Pyrrole-Imidazole Polyamide.
Author: Shinohara, Ken-Ichi|Yoda, Natsumi|Takane, Kiyoko|Watanabe, Takayoshi|Fukuyo, Masaki|Fujiwara, Kyoko|Kita, Kazuko|Nagase, Hiroki|Nemoto, Tetsuhiro|Kaneda, Atsushi
PMID: 30023504
Journal: Klin Onkol. Winter 2016;29(6):419-427.
Title: [Molecular Pathogenesis of Colorectal Cancer].
Author: Kral, J|Slyskova, J|Vodicka, P|Spicak, J
PMID: 27951718
Journal: Gut. 2017 Jan;66(1):97-106.
Title: Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Author: Bettington, Mark|Walker, Neal|Rosty, Christophe|Brown, Ian|Clouston, Andrew|McKeone, Diane|Pearson, Sally-Ann|Leggett, Barbara|Whitehall, Vicki
PMID: 26475632
Journal: Gut. 2017 Mar;66(3):464-472.
Title: Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database.
Author: Moller, Pal|Seppala, Toni|Bernstein, Inge|Holinski-Feder, Elke|Sala, Paola|Evans, D Gareth|Lindblom, Annika|Macrae, Finlay|Blanco, Ignacio|Sijmons, Rolf|Jeffries, Jacqueline|Vasen, Hans|Burn, John|Nakken, Sigve|Hovig, Eivind|Rodland, Einar Andreas|Tharmar
PMID: 26657901
Journal: Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):399-406.
Title: Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency.
Author: Xia, Michelle|Singhi, Aatur D|Dudley, Beth|Brand, Randall|Nikiforova, Marina|Pai, Reetesh K
PMID: 27258561
Journal: Gut. 2017 Sep;66(9):1657-1664.
Title: Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database.
Author: Moller, Pal|Seppala, Toni|Bernstein, Inge|Holinski-Feder, Elke|Sala, Paola|Evans, D Gareth|Lindblom, Annika|Macrae, Finlay|Blanco, Ignacio|Sijmons, Rolf|Jeffries, Jacqueline|Vasen, Hans|Burn, John|Nakken, Sigve|Hovig, Eivind|Rodland, Einar Andreas|Tharmar
PMID: 27261338
Journal: J Gastroenterol Hepatol. 2017 Feb;32(2):427-438.
Title: Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts.
Author: Buchanan, Daniel D|Clendenning, Mark|Rosty, Christophe|Eriksen, Stine V|Walsh, Michael D|Walters, Rhiannon J|Thibodeau, Stephen N|Stewart, Jenna|Preston, Susan|Win, Aung Ko|Flander, Louisa|Ouakrim, Driss Ait|Macrae, Finlay A|Boussioutas, Alex|Winship, Ing
PMID: 27273229
Journal: Gut. 2017 Sep;66(9):1645-1656.
Title: RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
Author: Yan, Helen H N|Lai, Jeffrey C W|Ho, Siu Lun|Leung, Wai Keung|Law, Wai Lun|Lee, Janet F Y|Chan, Anthony K W|Tsui, Wai Yin|Chan, Annie S Y|Lee, Bernard C H|Yue, Sarah S K|Man, Alice H Y|Clevers, Hans|Yuen, Siu Tsan|Leung, Suet Yi
PMID: 27329244
Journal: Histopathology. 2017 Jan;70(2):309-313.
Title: Long-term survival of patients with mismatch repair protein-deficient, high-stage ovarian clear cell carcinoma.
Author: Stewart, Colin J R|Bowtell, David D L|Doherty, Dorota A|Leung, Yee C
PMID: 27442838
Journal: Fam Cancer. 2017 Jan;16(1):57-66.
Title: First description of mutational analysis of MLH1, MSH2 and MSH6 in Algerian families with suspected Lynch syndrome.
Author: Ziada-Bouchaar, H|Sifi, K|Filali, T|Hammada, T|Satta, D|Abadi, N
PMID: 27468915
Journal: Int J Gynecol Pathol. 2017 May;36(3):205-216.
Title: Mucinous Differentiation With Tumor Infiltrating Lymphocytes Is a Feature of Sporadically Methylated Endometrial Carcinomas.
Author: Sloan, Emily A|Moskaluk, Christopher A|Mills, Anne M
PMID: 27513077
Journal: Clin Gastroenterol Hepatol. 2017 Mar;15(3):454-458.e1.
Title: Colorectal Cancer Risk in Patients With Lynch Syndrome and Inflammatory Bowel Disease.
Author: Derikx, Lauranne A A P|Smits, Lisa J T|van Vliet, Shannon|Dekker, Evelien|Aalfs, Cora M|van Kouwen, Mariette C A|Nagengast, Fokko M|Nagtegaal, Iris D|Hoogerbrugge, Nicoline|Hoentjen, Frank
PMID: 27521512
Journal: Int J Gynecol Pathol. 2017 Mar;36(2):115-127.
Title: Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like Syndrome.
Author: Watkins, Jaclyn C|Yang, Eric J|Muto, Michael G|Feltmate, Colleen M|Berkowitz, Ross S|Horowitz, Neil S|Syngal, Sapna|Yurgelun, Matthew B|Chittenden, Anu|Hornick, Jason L|Crum, Christopher P|Sholl, Lynette M|Howitt, Brooke E
PMID: 27556954
Journal: Gastroenterology. 2017 Jan;152(1):193-205.e10.
Title: Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.
Author: Wang, Yiwei|Huang, Dan|Chen, Kai-Yuan|Cui, Min|Wang, Weihuan|Huang, Xiaoran|Awadellah, Amad|Li, Qing|Friedman, Ann|Xin, William W|Di Martino, Luca|Cominelli, Fabio|Miron, Alex|Chan, Ricky|Fox, James G|Xu, Yan|Shen, Xiling|Kalady, Mathew F|Markowitz, Sanfo
PMID: 27639802
Journal: J Clin Pathol. 2017 Apr;70(4):331-356.
Title: The role of miRNA-21 and epithelial mesenchymal transition (EMT) process in colorectal cancer.
Author: Jaca, Anelisa|Govender, Padmini|Locketz, Michael|Naidoo, Richard
PMID: 27672217
Journal: Cancer Epidemiol Biomarkers Prev. 2017 Mar;26(3):404-412.
Title: Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer.
Author: Win, Aung Ko|Jenkins, Mark A|Dowty, James G|Antoniou, Antonis C|Lee, Andrew|Giles, Graham G|Buchanan, Daniel D|Clendenning, Mark|Rosty, Christophe|Ahnen, Dennis J|Thibodeau, Stephen N|Casey, Graham|Gallinger, Steven|Le Marchand, Loic|Haile, Robert W|Potte
PMID: 27799157
Journal: Eur J Surg Oncol. 2017 Feb;43(2):311-321.
Title: Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
Author: Ghanipour, L|Jirstrom, K|Sundstrom, M|Glimelius, B|Birgisson, H
PMID: 27836416
Journal: Histopathology. 2017 Mar;70(4):664-669.
Title: Cytoplasmic MSH2 immunoreactivity in a patient with Lynch syndrome with an EPCAM-MSH2 fusion.
Author: Sekine, Shigeki|Ogawa, Reiko|Saito, Shinya|Ushiama, Mineko|Shida, Dai|Nakajima, Takeshi|Taniguchi, Hirokazu|Hiraoka, Nobuyoshi|Yoshida, Teruhiko|Sugano, Kokichi
PMID: 27896849
Journal: Jpn J Clin Oncol. 2017 Feb 9;47(2):108-117.
Title: Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population.
Author: Chika, Noriyasu|Eguchi, Hidetaka|Kumamoto, Kensuke|Suzuki, Okihide|Ishibashi, Keiichiro|Tachikawa, Tetsuhiko|Akagi, Kiwamu|Tamaru, Jun-Ichi|Okazaki, Yasushi|Ishida, Hideyuki
PMID: 27920101
Journal: J Obstet Gynaecol Res. 2017 Feb;43(2):416-420.
Title: Carcinoma of the lower uterine segment diagnosed with Lynch syndrome based on MSH6 germline mutation: A case report.
Author: Adachi, Masataka|Banno, Kouji|Masuda, Kenta|Yanokura, Megumi|Iijima, Moito|Takeda, Takashi|Kunitomi, Haruko|Kobayashi, Yusuke|Yamagami, Wataru|Hirasawa, Akira|Kameyama, Kaori|Sugano, Kokichi|Aoki, Daisuke
PMID: 27928858
Journal: JAMA Oncol. 2017 Apr 1;3(4):464-471.
Title: Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
Author: Pearlman, Rachel|Frankel, Wendy L|Swanson, Benjamin|Zhao, Weiqiang|Yilmaz, Ahmet|Miller, Kristin|Bacher, Jason|Bigley, Christopher|Nelsen, Lori|Goodfellow, Paul J|Goldberg, Richard M|Paskett, Electra|Shields, Peter G|Freudenheim, Jo L|Stanich, Peter P|Lat
PMID: 27978560
Journal: Dig Dis Sci. 2017 Feb;62(2):299-304.
Title: Approach to Lynch Syndrome for the Gastroenterologist.
Author: Bui, Quan M|Lin, David|Ho, Wendy
PMID: 27990589
Journal: Mod Pathol. 2017 Mar;30(3):440-447.
Title: A tailored approach to BRAF and MLH1 methylation testing in a universal screening program for Lynch syndrome.
Author: Adar, Tomer|Rodgers, Linda H|Shannon, Kristen M|Yoshida, Makoto|Ma, Tianle|Mattia, Anthony|Lauwers, Gregory Y|Iafrate, Anthony J|Chung, Daniel C
PMID: 28059100
Journal: Clin Colorectal Cancer. 2017 Sep;16(3):228-239.
Title: Response to Chemotherapy and Prognosis in Metastatic Colorectal Cancer With DNA Deficient Mismatch Repair.
Author: Alex, Alexandra Khichfy|Siqueira, Sheila|Coudry, Renata|Santos, Juliana|Alves, Michel|Hoff, Paulo M|Riechelmann, Rachel P
PMID: 28063788
Journal: Clin Sci (Lond). 2017 Mar 1;131(6):471-485.
Title: Interactions between microsatellite instability and human gut colonization by Escherichia coli in colorectal cancer.
Author: Gagniere, Johan|Bonnin, Virginie|Jarrousse, Anne-Sophie|Cardamone, Emilie|Agus, Allison|Uhrhammer, Nancy|Sauvanet, Pierre|Dechelotte, Pierre|Barnich, Nicolas|Bonnet, Richard|Pezet, Denis|Bonnet, Mathilde
PMID: 28093453
Journal: Eur J Dermatol. 2017 Feb 1;27(1):54-58.
Title: Muir-Torre syndrome caused by exonic deletion of MLH1 due to homologous recombination.
Author: Shiki, Mirei|Hida, Tokimasa|Sugano, Kokichi|Kaneko, Rie|Kamiya, Takafumi|Sakurai, Akihiro|Yamashita, Toshiharu
PMID: 28120777
Journal: J Obstet Gynaecol Res. 2017 May;43(5):929-934.
Title: High-risk epithelial ovarian cancer patients for hereditary ovarian cancer.
Author: Chirasophon, Seksit|Manchana, Tarinee|Teerapakpinyo, Chinachote
PMID: 28188963
Journal: J Pathol Transl Med. 2017 Mar;51(2):129-136.
Title: Comparison of the Mismatch Repair System between Primary and Metastatic Colorectal Cancers Using Immunohistochemistry.
Author: Jung, Jiyoon|Kang, Youngjin|Lee, Yoo Jin|Kim, Eojin|Ahn, Bokyung|Lee, Eunjung|Kim, Joo Young|Lee, Jeong Hyeon|Lee, Youngseok|Kim, Chul Hwan|Chae, Yang-Seok
PMID: 28192899
Journal: Nat Commun. 2017 Feb 14;8:14418.
Title: The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.
Author: Liu, Ning Qing|Ter Huurne, Menno|Nguyen, Luan N|Peng, Tianran|Wang, Shuang-Yin|Studd, James B|Joshi, Onkar|Ongen, Halit|Bramsen, Jesper B|Yan, Jian|Andersen, Claus L|Taipale, Jussi|Dermitzakis, Emmanouil T|Houlston, Richard S|Hubner, Nina C|Stunnenberg, H
PMID: 28195176
Journal: Pathol Res Pract. 2017 Apr;213(4):333-338.
Title: Expression and promoter DNA methylation of MLH1 in colorectal cancer and lung cancer.
Author: Ma, Yunxia|Chen, Yuan|Petersen, Iver
PMID: 28214209
Journal: Curr Treat Options Oncol. 2017 Feb;18(2):9.
Title: BRAF-Mutated Colorectal Cancer: What Is the Optimal Strategy for Treatment?
Author: Cohen, Romain|Cervera, Pascale|Svrcek, Magali|Pellat, Anna|Dreyer, Chantal|de Gramont, Aimery|Andre, Thierry
PMID: 28214977
Journal: Mol Carcinog. 2017 Jul;56(7):1816-1824.
Title: Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.
Author: Hinrichsen, Inga|Ackermann, Anne|Duding, Tonja|Graband, Annika|Filmann, Natalie|Plotz, Guido|Zeuzem, Stefan|Brieger, Angela
PMID: 28224663
Journal: Hum Pathol. 2017 May;63:33-39.
Title: Neoadjuvant therapy in microsatellite-stable colorectal carcinoma induces concomitant loss of MSH6 and Ki-67 expression.
Author: Kuan, Shih-Fan|Ren, Bing|Brand, Randall|Dudley, Beth|Pai, Reetesh K
PMID: 28232158
Journal: Surg Today. 2017 Sep;47(9):1135-1146.
Title: Prevalence and clinicopathologic/molecular characteristics of mismatch repair-deficient colorectal cancer in the under-50-year-old Japanese population.
Author: Suzuki, Okihide|Eguchi, Hidetaka|Chika, Noriyasu|Sakimoto, Takehiko|Ishibashi, Keiichiro|Kumamoto, Kensuke|Tamaru, Jun-Ichi|Tachikawa, Tetsuhiko|Akagi, Kiwamu|Arai, Tomio|Okazaki, Yasushi|Ishida, Hideyuki
PMID: 28258479
Journal: Diagn Pathol. 2017 Mar 4;12(1):24.
Title: Molecular genetics of microsatellite-unstable colorectal cancer for pathologists.
Author: Chen, Wei|Swanson, Benjamin J|Frankel, Wendy L
PMID: 28259170
Journal: Br J Cancer. 2017 Apr 11;116(8):1012-1020.
Title: Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system.
Author: Bae, Jeong Mo|Kim, Jung Ho|Kwak, Yoonjin|Lee, Dae-Won|Cha, Yongjun|Wen, Xianyu|Lee, Tae Hun|Cho, Nam-Yun|Jeong, Seung-Yong|Park, Kyu Joo|Han, Sae Won|Lee, Hye Seung|Kim, Tae-You|Kang, Gyeong Hoon
PMID: 28278514
Journal: Open Access Maced J Med Sci. 2017 Mar 15;5(1):9-13.
Title: Mismatch Repair Proteins and Microsatellite Instability in Colorectal Carcinoma (MLH1, MSH2, MSH6 and PMS2): Histopathological and Immunohistochemical Study.
Author: Ismael, Nour El Hoda S|El Sheikh, Samar A|Talaat, Suzan M|Salem, Eman M
PMID: 28293308
Journal: Clin Epigenetics. 2017 Mar 9;9:26.
Title: The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer.
Author: Savio, Andrea J|Mrkonjic, Miralem|Lemire, Mathieu|Gallinger, Steven|Knight, Julia A|Bapat, Bharat
PMID: 28293327
Journal: Epigenetics. 2017 Jun 3;12(6):441-448.
Title: Modulation of transcription factor binding and epigenetic regulation of the MLH1 CpG island and shore by polymorphism rs1800734 in colorectal cancer.
Author: Savio, Andrea J|Bapat, Bharati
PMID: 28304185
Journal: Gastroenterol Hepatol Bed Bench. 2017 Winter;10(1):60-65.
Title: Person centered prediction of survival in population based screening program by an intelligent clinical decision support system.
Author: Safdari, Reza|Maserat, Elham|Asadzadeh Aghdaei, Hamid|Javan Amoli, Amir Hossein|Mohaghegh Shalmani, Hamid
PMID: 28331566
Journal: G3 (Bethesda). 2017 May 5;7(5):1463-1473.
Title: Schizosaccharomyces pombe MutSalpha and MutLalpha Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats.
Author: Villahermosa, Desiree|Christensen, Olaf|Knapp, Karen|Fleck, Oliver
PMID: 28341698
Journal: World J Gastrointest Oncol. 2017 Mar 15;9(3):105-120.
Title: CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Author: Sanchez-Vega, Francisco|Gotea, Valer|Chen, Yun-Ching|Elnitski, Laura
PMID: 28344746
Journal: Clin Genet. 2017 Dec;92(6):649-653.
Title: New EPCAM founder deletion in Polish population.
Author: Dymerska, D|Golebiewska, K|Kuswik, M|Rudnicka, H|Scott, R J|Billings, R|Plawski, A|Borun, P|Siolek, M|Kozak-Klonowska, B|Szwiec, M|Kilar, E|Huzarski, T|Byrski, T|Lubinski, J|Kurzawski, G
PMID: 28369810
Journal: BMC Med Genet. 2017 Apr 5;18(1):40.
Title: Homozygous germ-line mutation of the PMS2 mismatch repair gene: a unique case report of constitutional mismatch repair deficiency (CMMRD).
Author: Ramchander, N C|Ryan, N A J|Crosbie, E J|Evans, D G
PMID: 28381238
Journal: Oncotarget. 2017 Jun 13;8(24):38767-38779.
Title: Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-beta.
Author: Lu, Jun-Yu|Jin, Peng|Gao, Wei|Wang, De-Zhi|Sheng, Jian-Qiu
PMID: 28404976
Journal: Cancer Immunol Immunother. 2017 Jul;66(7):927-939.
Title: Prognostic implication of CD274 (PD-L1) protein expression in tumor-infiltrating immune cells for microsatellite unstable and stable colorectal cancer.
Author: Lee, Kyu Sang|Kwak, Yoonjin|Ahn, Soyeon|Shin, Eun|Oh, Heung-Kwon|Kim, Duck-Woo|Kang, Sung-Bum|Choe, Gheeyoung|Kim, Woo Ho|Lee, Hye Seung
PMID: 28405764
Journal: Biomed J. 2017 Feb;40(1):39-48.
Title: Overexpression of MutL homolog 1 and MutS homolog 2 proteins have reversed prognostic implications for stage I-II colon cancer patients.
Author: Huang, Shih-Chiang|Huang, Shiu-Feng|Chen, Ya-Ting|Chang, Yu|Chiu, Yu-Ting|Chang, Il-Chi|Wu, Hong-Dar Isaac|Chen, Jinn-Shiun
PMID: 28411881
Journal: Arch Pathol Lab Med. 2017 Jul;141(7):970-977.
Title: Morphological Features and Prognostic Significance of ARID1A-Deficient Esophageal Adenocarcinomas.
Author: Drage, Michael G|Tippayawong, Mingkhwan|Agoston, Agoston T|Zheng, Yifan|Bueno, Raphael|Hornick, Jason L|Odze, Robert D|Srivastava, Amitabh
PMID: 28440661
Journal: Oncotarget. 2017 Apr 11;8(15):24533-24547.
Title: A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients.
Author: Zhang, Junxiao|Wang, Xiaoyan|de Voer, Richarda M|Hehir-Kwa, Jayne Y|Kamping, Eveline J|Weren, Robbert D A|Nelen, Marcel|Hoischen, Alexander|Ligtenberg, Marjolijn J L|Hoogerbrugge, Nicoline|Yang, Xiangling|Yang, Zihuan|Fan, Xinjuan|Wang, Lei|Liu, Huanliang
PMID: 28445943
Journal: Clin Neurol Neurosurg. 2017 Jul;158:46-48.
Title: A rare case of choroid plexus carcinoma that led to the diagnosis of Lynch syndrome (hereditary nonpolyposis colorectal cancer).
Author: Zhu, Viola W|Hinduja, Sanjay|Knezevich, Stevan R|Silveira, William R|DeLozier, Celia D
PMID: 28460341
Journal: Nat Commun. 2017 May 3;8:14755.
Title: Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2.
Author: Haraldsdottir, Sigurdis|Rafnar, Thorunn|Frankel, Wendy L|Einarsdottir, Sylvia|Sigurdsson, Asgeir|Hampel, Heather|Snaebjornsson, Petur|Masson, Gisli|Weng, Daniel|Arngrimsson, Reynir|Kehr, Birte|Yilmaz, Ahmet|Haraldsson, Stefan|Sulem, Patrick|Stefansson, Tr
PMID: 28466842
Journal: Klin Onkol. 2017 Spring;30(Supplementum1):153-155.
Title: [Molecular Pathology of Colorectal Cancer, Microsatellite Instability - the Detection, the Relationship to the Pathophysiology and Prognosis].
Author: Brychtova, V|Sefr, R|Hrstka, R|Videnska, P|Bencsikova, B|Hanakova, B|Zdrazilova Dubska, L|Nenutil, R|Budinska, E
PMID: 28471193
Journal: Int J Mol Sci. 2017 May 6;18(5). pii: ijms18050999.
Title: Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome.
Author: Liccardo, Raffaella|De Rosa, Marina|Rossi, Giovanni Battista|Carlomagno, Nicola|Izzo, Paola|Duraturo, Francesca
PMID: 28481244
Journal: J Clin Oncol. 2017 Jul 1;35(19):2165-2172.
Title: Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome.
Author: Kastrinos, Fay|Uno, Hajime|Ukaegbu, Chinedu|Alvero, Carmelita|McFarland, Ashley|Yurgelun, Matthew B|Kulke, Matthew H|Schrag, Deborah|Meyerhardt, Jeffrey A|Fuchs, Charles S|Mayer, Robert J|Ng, Kimmie|Steyerberg, Ewout W|Syngal, Sapna
PMID: 28489507
Journal: Diagn Pathol. 2017 May 12;12(1):39.
Title: Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report.
Author: Trippel, Mafalda|Imboden, Sara|Papadia, Andrea|Mueller, Michael D|Mertineit, Nando|Harma, Kirsi|Nicolae, Alina|Vassella, Erik|Rau, Tilman T
PMID: 28494767
Journal: Genes Chromosomes Cancer. 2017 Sep;56(9):681-690.
Title: Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer.
Author: Meunier, Katy|Ferron, Marianne|Calmel, Claire|Flejou, Jean-Francois|Pocard, Marc|Praz, Francoise
PMID: 28512763
Journal: J Clin Oncol. 2017 Aug 1;35(22):2568-2575.
Title: Multigene Panel Testing Provides a New Perspective on Lynch Syndrome.
Author: Espenschied, Carin R|LaDuca, Holly|Li, Shuwei|McFarland, Rachel|Gau, Chia-Ling|Hampel, Heather
PMID: 28514183
Journal: Clin Cancer Res. 2017 Sep 1;23(17):5246-5254.
Title: Can Microsatellite Status of Colorectal Cancer Be Reliably Assessed after Neoadjuvant Therapy?
Author: Goldstein, Jennifer B|Wu, William|Borras, Ester|Masand, Gita|Cuddy, Amanda|Mork, Maureen E|Bannon, Sarah A|Lynch, Patrick M|Rodriguez-Bigas, Miguel|Taggart, Melissa W|Wu, Ji|Scheet, Paul|Kopetz, Scott|You, Y Nancy|Vilar, Eduardo
PMID: 28522602
Journal: J Menopausal Med. 2017 Apr;23(1):69-73.
Title: Case Report of Menopausal Woman Diagnosed with Endometrial Cancer after Colon Cancer with Germline Mutation in MSH6 in Korea.
Author: Lee, Hyun Jung|Lee, Min Hee|Choi, Min Chul|Jung, Sang Geun|Joo, Won Duk|Kim, Tae Hoen|Lee, Chan|Jang, Ja-Hyun
PMID: 28523262
Journal: Fam Cancer. 2017 Oct;16(4):491-500.
Title: Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6.
Author: Morak, Monika|Kasbauer, Sarah|Kerscher, Martina|Laner, Andreas|Nissen, Anke M|Benet-Pages, Anna|Schackert, Hans K|Keller, Gisela|Massdorf, Trisari|Holinski-Feder, Elke
PMID: 28528517
Journal: Clin Epigenetics. 2017 May 18;9:55.
Title: Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa.
Author: Sugai, Tamotsu|Yoshida, Masakazu|Eizuka, Makoto|Uesugii, Noriyuki|Habano, Wataru|Otsuka, Kouki|Sasaki, Akira|Yamamoto, Eiichiro|Matsumoto, Takayuki|Suzuki, Hiromu
PMID: 28533824
Journal: J Gastrointest Cancer. 2017 Jun 5. pii: 10.1007/s12029-017-9954-5.
Title: Clinical Impact of Mismatch Repair Protein Testing on Outcome of Early Staged Colorectal Carcinomas.
Author: Gandhi, Jatin Sundersham|Goswami, Malini|Sharma, Anila|Tanwar, Parul|Gupta, Gurudutt|Gupta, Nikhil|Pasricha, Sunil|Mehta, Anurag|Singh, Shivender|Agarwal, Mohit|Gupta, Nitin
PMID: 28585041
Journal: Oncotarget. 2017 Jun 20;8(25):39945-39962.
Title: BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
Author: Deihimi, Safoora|Lev, Avital|Slifker, Michael|Shagisultanova, Elena|Xu, Qifang|Jung, Kyungsuk|Vijayvergia, Namrata|Ross, Eric A|Xiu, Joanne|Swensen, Jeffrey|Gatalica, Zoran|Andrake, Mark|Dunbrack, Roland L|El-Deiry, Wafik S
PMID: 28591715
Journal: Med Sci Monit. 2017 Jun 21;23:3026-3038.
Title: Relationship Between Human mutL Homolog 1 (hMLH1) Hypermethylation and Colorectal Cancer: A Meta-Analysis.
Author: Zhang, Hui-Feng|Lu, You-Wang|Xie, Zhen-Rong|Wang, Kun-Hua
PMID: 28635682
Journal: Cancer. 2017 Oct 1;123(19):3732-3743.
Title: DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer.
Author: Ricker, Charite N|Hanna, Diana L|Peng, Cheng|Nguyen, Nathalie T|Stern, Mariana C|Schmit, Stephanie L|Idos, Greg E|Patel, Ravi|Tsai, Steven|Ramirez, Veronica|Lin, Sonia|Shamasunadara, Vinay|Barzi, Afsaneh|Lenz, Heinz-Josef|Figueiredo, Jane C
PMID: 28640387
Journal: Arch Iran Med. 2017 Jun;20(6):332-337.
Title: Screening for Lynch Syndrome in Cases with Colorectal Carcinoma from Mashhad.
Author: Goshayeshi, Ladan|Khooiee, Alireza|Ghaffarzadegan, Kamran|Rahmani Khorram, Mahla|Bishehsari, Faraz|Hoseini, Benyamin|Akhavan Rezayat, Kambiz|Esmaeilzadeh, Abbas|Mosannen Mozaffari, Hooman|Ghanayee, Omid|Lari, S|Bahari, Ali|Allahyari, Abolghasem|Bari, Alir
PMID: 28646840
Journal: World J Surg Oncol. 2017 Jun 26;15(1):116.
Title: Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters.
Author: Hashmi, Atif Ali|Ali, Rabia|Hussain, Zubaida Fida|Faridi, Naveen|Khan, Erum Yousuf|Bakar, Syed Muhammad Abu|Edhi, Muhammad Muzzammil|Khan, Mehmood
PMID: 28651545
Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K
PMID: 28675510
Journal: Dis Colon Rectum. 2017 Aug;60(8):792-799.
Title: Subtotal Colectomy for Colon Cancer Reduces the Need for Subsequent Surgery in Lynch Syndrome.
Author: Renkonen-Sinisalo, Laura|Seppala, Toni T|Jarvinen, Heikki J|Mecklin, Jukka-Pekka
PMID: 28682964
Journal: Oncol Lett. 2017 Jul;14(1):958-964.
Title: MLH1 expression predicts the response to preoperative therapy and is associated with PD-L1 expression in esophageal cancer.
Author: Momose, Kota|Yamasaki, Makoto|Tanaka, Koji|Miyazaki, Yasuhiro|Makino, Tomoki|Takahashi, Tsuyoshi|Kurokawa, Yukinori|Nakajima, Kiyokazu|Takiguchi, Shuji|Mori, Masaki|Doki, Yuichiro
PMID: 28693258
Journal: Crit Rev Oncol Hematol. 2017 Aug;116:38-57.
Title: The current value of determining the mismatch repair status of colorectal cancer: A rationale for routine testing.
Author: Ryan, E|Sheahan, K|Creavin, B|Mohan, H M|Winter, D C
PMID: 28693799
Journal: Curr Protoc Hum Genet. 2017 Jul 11;94:10.12.1-10.12.23.
Title: Genetic Testing for Hereditary Nonpolyposis Colorectal Cancer (HNPCC).
Author: Nallamilli, Babi Ramesh Reddy|Hegde, Madhuri
PMID: 28696559
Journal: J Gastrointest Cancer. 2017 Dec;48(4):305-313.
Title: Expending Role of Microsatellite Instability in Diagnosis and Treatment of Colorectal Cancers.
Author: Chang, Liisa|Chang, Minna|Chang, Hanna M|Chang, Fuju
PMID: 28699072
Journal: Med Oncol. 2017 Aug;34(8):147.
Title: Clinical and prognosis value of the CIMP status combined with MLH1 or p16 (INK4a) methylation in colorectal cancer.
Author: Saadallah-Kallel, Amana|Abdelmaksoud-Dammak, Rania|Triki, Mouna|Charfi, Slim|Khabir, Abdelmajid|Sallemi-Boudawara, Tahia|Mokdad-Gargouri, Raja
PMID: 28730335
Journal: J BUON. 2017 May-Jun;22(3):606-609.
Title: DNA mismatch repair deficiency in lung and oral cavity carcinomas: the role of histogenetic origin.
Author: Spetsotaki, Konstantina N|Tsiambas, Evangelos|Stamatelopoulos, Athanasios|Fotiades, Panagiotis P|Kastanioudakis, Ioannis|Tomos, Pericles|Ragos, Vasileios
PMID: 28730763
Journal: J Cutan Pathol. 2017 Nov;44(11):931-937.
Title: Review of the current medical literature and assessment of current utilization patterns regarding mismatch repair protein immunohistochemistry in cutaneous Muir-Torre syndrome-associated neoplasms.
Author: Lee, Jason B|Litzner, Brandon R|Vidal, Claudia I
PMID: 28749576
Journal: Mod Pathol. 2017 Dec;30(12):1728-1738.
Title: Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry.
Author: Liu, Cheng|Walker, Neal I|Leggett, Barbara A|Whitehall, Vicki Lj|Bettington, Mark L|Rosty, Christophe
PMID: 28752838
Journal: Ther Clin Risk Manag. 2017 Jul 21;13:915-918.
Title: Thyroid cancer in a patient with Lynch syndrome - case report and literature review.
Author: Fazekas-Lavu, Monika|Parker, Andrew|Spigelman, Allan D|Scott, Rodney J|Epstein, Richard J|Jensen, Michael|Samaras, Katherine
PMID: 28769567
Journal: JAMA Oncol. 2017 Dec 1;3(12):1702-1706.
Title: Association of Mismatch Repair Mutation With Age at Cancer Onset in Lynch Syndrome: Implications for Stratified Surveillance Strategies.
Author: Ryan, Neil A J|Morris, Julie|Green, Kate|Lalloo, Fiona|Woodward, Emma R|Hill, James|Crosbie, Emma J|Evans, D Gareth
PMID: 28772289
Journal: Cancer Epidemiol. 2017 Oct;50(Pt A):30-38.
Title: High-risk family colorectal cancer screening service in Ireland: Critical review of clinical outcomes.
Author: Walshe, Margaret|Moran, Robert|Boyle, Marie|Cretu, Ion|Galvin, Zita|Swan, Victoria|Trikovic, Jason|Farrell, Michael P|Foy, Sinead|O'Brien, Loretta|Leyden, Jan|Mulligan, Niall|Fenlon, Helen|Gallagher, David J|MacMathuna, Padraic
PMID: 28783501
Journal: Sci Rep. 2017 Aug 11;7(1):7882.
Title: Differences of protein expression profiles, KRAS and BRAF mutation, and prognosis in right-sided colon, left-sided colon and rectal cancer.
Author: Gao, Xian Hua|Yu, Guan Yu|Gong, Hai Feng|Liu, Lian Jie|Xu, Yi|Hao, Li Qiang|Liu, Peng|Liu, Zhi Hong|Bai, Chen Guang|Zhang, Wei
PMID: 28801584
Journal: Case Rep Pathol. 2017;2017:3427343.
Title: Gastric Medullary Carcinoma with Sporadic Mismatch Repair Deficiency and a TP53 R273C Mutation: An Unusual Case with Wild-Type BRAF.
Author: Lowenthal, Brett M|Chan, Theresa W|Thorson, John A|Kelly, Kaitlyn J|Savides, Thomas J|Valasek, Mark A
PMID: 28840050
Journal: Ann Ital Chir. 2017;6:425-432.
Title: The prognostic role of microsatellite instability in colorectal cancer patients.
Author: Micu, Bogdan V|Andercou, Octavian|Vesa, Stefan C|Micu, Carmen M|Pop, Tudor R|Constantea, Nicolae
PMID: 28874631
Journal: Sci Rep. 2017 Sep 6;7(1):10696.
Title: MicroRNA-449a deficiency promotes colon carcinogenesis.
Author: Niki, Masanori|Nakajima, Kohei|Ishikawa, Daichi|Nishida, Jun|Ishifune, Chieko|Tsukumo, Shin-Ichi|Shimada, Mitsuo|Nagahiro, Shinji|Mitamura, Yoshinori|Yasutomo, Koji
PMID: 28878284
Journal: Health Technol Assess. 2017 Sep;21(51):1-238.
Title: Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation.
Author: Snowsill, Tristan|Coelho, Helen|Huxley, Nicola|Jones-Hughes, Tracey|Briscoe, Simon|Frayling, Ian M|Hyde, Chris
PMID: 28895526
Journal: Science. 2017 Oct 13;358(6360):234-238.
Title: Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.
Author: Drost, Jarno|van Boxtel, Ruben|Blokzijl, Francis|Mizutani, Tomohiro|Sasaki, Nobuo|Sasselli, Valentina|de Ligt, Joep|Behjati, Sam|Grolleman, Judith E|van Wezel, Tom|Nik-Zainal, Serena|Kuiper, Roland P|Cuppen, Edwin|Clevers, Hans
PMID: 28912133
Journal: Oncol Lett. 2017 Sep;14(3):3683-3688.
Title: Protein expression of Fragile Histidine Triad and cyclooxgenase-2 in serrated neoplasia of the colorectum.
Author: Tamoto, Akihiro|Yashima, Kazuo|Hosoda, Kohei|Yamamoto, Sohei|Kawata, Soichiro|Ikebuchi, Yuichiro|Matsumoto, Kazuya|Kawaguchi, Koichiro|Harada, Kenichi|Murawaki, Yoshikazu|Isomoto, Hajime
PMID: 28927131
Journal: Mol Genet Genomic Med. 2017 Jul 23;5(5):553-569.
Title: Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.
Author: DeRycke, Melissa S|Gunawardena, Shanaka|Balcom, Jessica R|Pickart, Angela M|Waltman, Lindsey A|French, Amy J|McDonnell, Shannon|Riska, Shaun M|Fogarty, Zachary C|Larson, Melissa C|Middha, Sumit|Eckloff, Bruce W|Asmann, Yan W|Ferber, Matthew J|Haile, Rober
PMID: 28944238
Journal: Int J Mol Med. 2017 Nov;40(5):1457-1465.
Title: Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer.
Author: Toth, Csaba|Sukosd, Farkas|Valicsek, Erzsebet|Herpel, Esther|Schirmacher, Peter|Renner, Marcus|Mader, Christoph|Tiszlavicz, Laszlo|Kriegsmann, Jorg
PMID: 28949378
Journal: Bull Cancer. 2017 Oct;104(10):831-839.
Title: The identification of Lynch syndrome in Congolese colorectal cancer patients.
Author: Poaty, Henriette|Aba Gandzion, Chandra|Soubeyran, Isabelle|Gassaye, Deby|Peko, Jean Felix|Nkoua Bon, Jean Bernard|Gombe Mbalawa, Charles
PMID: 28988047
Journal: Pathol Res Pract. 2017 Dec;213(12):1552-1555.
Title: PD-L1 expression in HNPCC-associated colorectal cancer.
Author: Shiraliyeva, Naila|Friedrichs, Jacqueline|Buettner, Reinhard|Friedrichs, Nicolaus
PMID: 29033182
Journal: Hered Cancer Clin Pract. 2017 Oct 10;15:18.
Title: Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report.
Author: Seppala, Toni|Pylvanainen, Kirsi|Evans, Dafydd Gareth|Jarvinen, Heikki|Renkonen-Sinisalo, Laura|Bernstein, Inge|Holinski-Feder, Elke|Sala, Paola|Lindblom, Annika|Macrae, Finlay|Blanco, Ignacio|Sijmons, Rolf|Jeffries, Jacqueline|Vasen, Hans|Burn, John|Nakk
PMID: 29046738
Journal: Oncotarget. 2017 May 10;8(42):71574-71586.
Title: Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
Author: Jahid, Sohail|Sun, Jian|Gelincik, Ozkan|Blecua, Pedro|Edelmann, Winfried|Kucherlapati, Raju|Zhou, Kathy|Jasin, Maria|Gumus, Zeynep H|Lipkin, Steven M
PMID: 29069730
Journal: Curr Genomics. 2017 Aug;18(4):341-359.
Title: Familial Colorectal Cancer Type X.
Author: Zetner, Diana Bregner|Bisgaard, Marie Luise
PMID: 29081690
Journal: Oncol Lett. 2017 Oct;14(4):4923-4929.
Title: HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.
Author: Tao, Xiangxiang|Yan, Yifeng|Lu, Linming|Chen, Bing
PMID: 29085502
Journal: J Cancer. 2017 Sep 15;8(16):3232-3241.
Title: Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells.
Author: Jin, Peng|Wang, De-Zhi|Lyu, Chen-Xi|Wang, Ya-Ting|He, Yu-Qi|Sheng, Jian-Qiu|Li, Xuhang
PMID: 29158795
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Nov 25;20(11):1222-1226.
Title: [Current status of hereditary gastrointestinal neoplasms].
Author: He, Yulong
PMID: 29178089
Journal: Arch Med Sci. 2017 Oct;13(6):1295-1302.
Title: Polymorphism of MSH2 Gly322Asp and MLH1 -93G>A in non-familial colon cancer - a case-controlled study.
Author: Mik, Michal|Dziki, Lukasz|Malinowska, Katarzyna|Trzcinski, Radzislaw|Majsterek, Ireneusz|Dziki, Adam
PMID: 29181059
Journal: J Gastrointest Oncol. 2017 Oct;8(5):E73-E79.
Title: Pancreatic non-functioning neuroendocrine tumor: a new entity genetically related to Lynch syndrome.
Author: Serracant Barrera, Anna|Serra Pla, Sheila|Blazquez Mana, Carmen Maria|Salas, Ruben Carrera|Garcia Monforte, Neus|Bejarano Gonzalez, Natalia|Romaguera Monzonis, Andreu|Andreu Navarro, Francisco Javier|Bella Cueto, Maria Rosa|Borobia, Francisco G
PMID: 29184699
Journal: Nature. 2017 Dec 7;552(7683):116-120.
Title: Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.
Author: Germano, Giovanni|Lamba, Simona|Rospo, Giuseppe|Barault, Ludovic|Magri, Alessandro|Maione, Federica|Russo, Mariangela|Crisafulli, Giovanni|Bartolini, Alice|Lerda, Giulia|Siravegna, Giulia|Mussolin, Benedetta|Frapolli, Roberta|Montone, Monica|Morano, Feder
PMID: 29186113
Journal: Oncotarget. 2017 Jun 21;8(55):93450-93463.
Title: Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort.
Author: Raskin, Leon|Guo, Yan|Du, Liping|Clendenning, Mark|Rosty, Christophe|Lindor, Noralane M|Gruber, Stephen B|Buchanan, Daniel D
PMID: 29212164
Journal: BMC Cancer. 2017 Dec 13;17(1):843.
Title: Prevalence and characteristics of hereditary non-polyposis colorectal cancer (HNPCC) syndrome in immigrant Asian colorectal cancer patients.
Author: Lee, Jasmine|Xiao, Yin-Yi|Sun, Yan Yu|Balderacchi, Jasminka|Clark, Bradley|Desani, Jatin|Kumar, Vivek|Saverimuthu, Angela|Win, Khin Than|Huang, Yiwu|Xu, Yiqing
PMID: 29237405
Journal: GE Port J Gastroenterol. 2017 Sep;24(5):241-246.
Title: Uncertainties in the Management of a Lynch Syndrome Patient: A Case Report.
Author: Campos, Sara|Amaro, Pedro|Cunha, Ines|Fraga, Joao|Cipriano, Maria Augusta|Tome, Luis
PMID: 29255760
Journal: Gastroenterol Hepatol Bed Bench. 2017 Winter;10(Suppl1):S117-S121.
Title: Evaluation of promoter methylation status of MLH1 gene in Iranian patients with colorectal tumors and adenoma polyps.
Author: Zarandi, Ashkan|Irani, Shiva|Savabkar, Sanaz|Chaleshi, Vahid|Ghavideldarestani, Maryam|Mirfakhraie, Reza|Khodadoostan, Mahsa|Nazemalhosseini-Mojarad, Ehsan|Asadzadeh Aghdaei, Hamid
PMID: 29511481
Journal: Tunis Med. 2017 Dec;95(12):229-236.
Title: Prognostic values of detecting MSI phenotypes in colorectal carcinoma by immunohistochemical method compared to molecular investigation.
Author: Trabelsi, Mona|Farah, Faten|Blel, Ahlem|Jaafoura, Mohamed Habib|Kharrat, Maher|Rammeh, Soumaya
PMID: 29878286
Journal: JCO Precis Oncol. 2017;2017. Epub 2017 Apr 27.
Title: Exceptional Chemotherapy Response in Metastatic Colorectal Cancer Associated With Hyper-Indel-Hypermutated Cancer Genome and Comutation of POLD1 and MLH1.
Author: Sharma, Manish R|Auman, James T|Patel, Nirali M|Grilley-Olson, Juneko E|Zhao, Xiaobei|Moschos, Stergios J|Parker, Joel S|Yin, Xiaoying|Hayward, Michele C|Polite, Blase N|Marangon, Elena|Posocco, Bianca|Toffoli, Giuseppe|Hayes, D Neil|Innocenti, Federico
PMID: 30009279
Journal: Singapore Med J. 2018 Mar;59(3):139-143.
Title: Extent of field change in colorectal cancers with BRAF mutation.
Author: Poh, Aaron|Chang, Heidi Sian Ying|Tan, Kok Yang|Sam, Xin Xiu|Khoo, Avery|Choo, Shoa Nian|Nga, Min En|Wan, Wei Keat
PMID: 28210747
Journal: Fam Cancer. 2018 Jan;17(1):63-69.
Title: RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.
Author: Fennell, Lochlan J|Clendenning, Mark|McKeone, Diane M|Jamieson, Saara H|Balachandran, Samanthy|Borowsky, Jennifer|Liu, John|Kawamata, Futoshi|Bond, Catherine E|Rosty, Christophe|Burge, Matthew E|Buchanan, Daniel D|Leggett, Barbara A|Whitehall, Vicki L J
PMID: 28573495
Journal: Fam Cancer. 2018 Jan;17(1):79-86.
Title: Constitutional mismatch repair deficiency and Lynch syndrome among consecutive Arab Bedouins with colorectal cancer in Israel.
Author: Abu Freha, Naim|Leibovici Weissman, Yaara|Fich, Alexander|Barnes Kedar, Inbal|Halpern, Marisa|Sztarkier, Ignacio|Behar, Doron M|Arbib Sneh, Orly|Vilkin, Alex|Baris, Hagit N|Gingold, Rachel|Lejbkowicz, Flavio|Niv, Yaron|Goldberg, Yael|Levi, Zohar
PMID: 28608265
Journal: Fam Cancer. 2018 Jan;17(1):91-100.
Title: Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas.
Author: Clendenning, Mark|Huang, Alvin|Jayasekara, Harindra|Lorans, Marie|Preston, Susan|O'Callaghan, Neil|Pope, Bernard J|Macrae, Finlay A|Winship, Ingrid M|Milne, Roger L|Giles, Graham G|English, Dallas R|Hopper, John L|Win, Aung K|Jenkins, Mark A|Southey, Meli
PMID: 28616688
Journal: Fam Cancer. 2018 Apr;17(2):197-203.
Title: Screening for Lynch syndrome in young Saudi colorectal cancer patients using microsatellite instability testing and next generation sequencing.
Author: Alqahtani, Masood|Edwards, Caitlin|Buzzacott, Natasha|Carpenter, Karen|Alsaleh, Khalid|Alsheikh, Abdulmalik|Abozeed, Waleed|Mashhour, Miral|Almousa, Afnan|Housawi, Yousef|Al Hawwaj, Shareefa|Iacopetta, Barry
PMID: 28643016
Journal: Gut. 2018 Jul;67(7):1306-1316.
Title: Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database.
Author: Moller, Pal|Seppala, Toni T|Bernstein, Inge|Holinski-Feder, Elke|Sala, Paulo|Gareth Evans, D|Lindblom, Annika|Macrae, Finlay|Blanco, Ignacio|Sijmons, Rolf H|Jeffries, Jacqueline|Vasen, Hans F A|Burn, John|Nakken, Sigve|Hovig, Eivind|Rodland, Einar Andreas
PMID: 28754778
Journal: Fam Cancer. 2018 Apr;17(2):225-228.
Title: Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations.
Author: Wang, Tao|Stadler, Zsofia K|Zhang, Liying|Weiser, Martin R|Basturk, Olca|Hechtman, Jaclyn F|Vakiani, Efsevia|Saltz, Lenard B|Klimstra, David S|Shia, Jinru
PMID: 28819720
Journal: Am J Surg Pathol. 2018 Feb;42(2):172-182.
Title: Clinicopathologic and Molecular Characteristics of Synchronous Colorectal Carcinoma With Mismatch Repair Deficiency.
Author: Nakano, Kayoko|Yamamoto, Hidetaka|Fujiwara, Minako|Koga, Yutaka|Tsuruta, Shinichi|Ihara, Eikichi|Oki, Eiji|Nakamura, Masafumi|Ogawa, Yoshihiro|Oda, Yoshinao
PMID: 28877066
Journal: Virchows Arch. 2018 Mar;472(3):383-393.
Title: Distinct histopathological characteristics in colorectal submucosal invasive carcinoma arising in sessile serrated adenoma/polyp and conventional tubular adenoma.
Author: Murakami, Takashi|Mitomi, Hiroyuki|Yao, Takashi|Saito, Tsuyoshi|Shibuya, Tomoyoshi|Sakamoto, Naoto|Osada, Taro|Watanabe, Sumio
PMID: 28929387
Journal: Fam Cancer. 2018 Jul;17(3):387-394.
Title: Screening for germline mutations in mismatch repair genes in patients with Lynch syndrome by next generation sequencing.
Author: Soares, Barbara Luisa|Brant, Ayslan Castro|Gomes, Renan|Pastor, Tatiane|Schneider, Naye Balzan|Ribeiro-Dos-Santos, Andrea|de Assumpcao, Paulo Pimentel|Achatz, Maria Isabel W|Ashton-Prolla, Patricia|Moreira, Miguel Angelo Martins
PMID: 28932927
Journal: Fam Cancer. 2018 Jul;17(3):361-370.
Title: Evaluation of current prediction models for Lynch syndrome: updating the PREMM5 model to identify PMS2 mutation carriers.
Author: Goverde, A|Spaander, M C W|Nieboer, D|van den Ouweland, A M W|Dinjens, W N M|Dubbink, H J|Tops, C J|Ten Broeke, S W|Bruno, M J|Hofstra, R M W|Steyerberg, E W|Wagner, A
PMID: 28933000
Journal: Am J Surg Pathol. 2018 Jan;42(1):60-68.
Title: Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.
Author: Ryan, Eanna|Khaw, Yi Ling|Creavin, Ben|Geraghty, Robert|Ryan, Elizabeth J|Gibbons, David|Hanly, Ann|Martin, Sean T|O'Connell, P Ronan|Winter, Desmond C|Sheahan, Kieran
PMID: 29112018
Journal: Fam Cancer. 2018 Jul;17(3):415-420.
Title: Excluding Lynch syndrome in a female patient with metachronous DNA mismatch repair deficient colon- and ovarian cancer.
Author: Crobach, Stijn|Jansen, Anne M L|Ligtenberg, Marjolein J L|Koopmans, Marije|Nielsen, Maartje|Hes, Frederik J|Wijnen, Juul T|Dinjens, Winand N M|van Wezel, Tom|Morreau, Hans
PMID: 29124495
Journal: Fam Cancer. 2018 Jul;17(3):395-402.
Title: Universal determination of microsatellite instability using BAT26 as a single marker in an Argentine colorectal cancer cohort.
Author: Gonzalez, Maria Laura|Causada-Calo, Natalia|Santino, Juan Pablo|Dominguez-Valentin, Mev|Ferro, Fabiana Alejandra|Sammartino, Ines|Kalfayan, Pablo German|Verzura, Maria Alicia|Pinero, Tamara Alejandra|Cajal, Andrea Romina|Pavicic, Walter|Vaccaro, Carlos
PMID: 29128931
Journal: Gastroenterology. 2018 Mar;154(4):897-905.e1.
Title: Germline Genetic Features of Young Individuals With Colorectal Cancer.
Author: Stoffel, Elena M|Koeppe, Erika|Everett, Jessica|Ulintz, Peter|Kiel, Mark|Osborne, Jenae|Williams, Linford|Hanson, Kristen|Gruber, Stephen B|Rozek, Laura S
PMID: 29146522
Journal: Fam Cancer. 2018 Oct;17(4):507-515.
Title: SNP association study in PMS2-associated Lynch syndrome.
Author: Ten Broeke, Sanne W|Elsayed, Fadwa A|Pagan, Lisa|Olderode-Berends, Maran J W|Garcia, Encarna Gomez|Gille, Hans J P|van Hest, Liselot P|Letteboer, Tom G W|van der Kolk, Lizet E|Mensenkamp, Arjen R|van Os, Theo A|Spruijt, Liesbeth|Redeker, Bert J W|Suerink,
PMID: 29147930
Journal: Biochimie. 2018 Mar;146:87-96.
Title: DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Author: de Barros, Andrea C|Takeda, Agnes A S|Dreyer, Thiago R|Velazquez-Campoy, Adrian|Kobe, Bostjan|Fontes, Marcos R M
PMID: 29175432
Journal: J Gastrointest Cancer. 2018 Mar;49(1):93-96.
Title: Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Biliary Tract Cancers Associated with Lynch Syndrome.
Author: Cloyd, Jordan M|Chun, Yun Shin|Ikoma, Naruhiko|Vauthey, Jean Nicolas|Aloia, Tlhomas A|Cuddy, Amanda|Rodriguez-Bigas, Miguel A|Nancy You, Y
PMID: 29238914
Journal: BMC Cancer. 2018 Jan 5;18(1):35.
Title: MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAF(V600E) mutation.
Author: Fennell, Lochlan J|Jamieson, Saara|McKeone, Diane|Corish, Tracie|Rohdmann, Megan|Furner, Tori|Bettington, Mark|Liu, Cheng|Kawamata, Futoshi|Bond, Catherine|Van De Pols, Jolieke|Leggett, Barbara|Whitehall, Vicki
PMID: 29304767
Journal: Hum Pathol. 2018 Apr;74:54-63.
Title: Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain?
Author: Huhns, Maja|Krohn, Saskia|Murua Escobar, Hugo|Prall, Friedrich
PMID: 29307628
Journal: Int J Clin Oncol. 2018 Jun;23(3):504-513.
Title: Differences in histological features and PD-L1 expression between sporadic microsatellite instability and Lynch-syndrome-associated disease in Japanese patients with colorectal cancer.
Author: Yamada, Rin|Yamaguchi, Tatsuro|Iijima, Takeru|Wakaume, Rika|Takao, Misato|Koizumi, Koichi|Hishima, Tsunekazu|Horiguchi, Shin-Ichiro
PMID: 29327160
Journal: Cancer Med. 2018 Feb;7(2):433-444.
Title: Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation.
Author: Pinto, Diana|Pinto, Carla|Guerra, Joana|Pinheiro, Manuela|Santos, Rui|Vedeld, Hege Marie|Yohannes, Zeremariam|Peixoto, Ana|Santos, Catarina|Pinto, Pedro|Lopes, Paula|Lothe, Ragnhild|Lind, Guro Elisabeth|Henrique, Rui|Teixeira, Manuel R
PMID: 29341452
Journal: Virchows Arch. 2018 Apr;472(4):653-665.
Title: High immune cell score predicts improved survival in pancreatic cancer.
Author: Tahkola, Kyosti|Mecklin, Jukka-Pekka|Wirta, Erkki-Ville|Ahtiainen, Maarit|Helminen, Olli|Bohm, Jan|Kellokumpu, Ilmo
PMID: 29356891
Journal: World J Gastrointest Oncol. 2018 Jan 15;10(1):1-14.
Title: Inflammation-associated microsatellite alterations: Mechanisms and significance in the prognosis of patients with colorectal cancer.
Author: Koi, Minoru|Tseng-Rogenski, Stephanie S|Carethers, John M
PMID: 29375743
Journal: Gut. 2018 Mar;67(3):447-455.
Title: Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment.
Author: Rigter, Lisanne S|Snaebjornsson, Petur|Rosenberg, Efraim H|Atmodimedjo, Peggy N|Aleman, Berthe M|Ten Hoeve, Jelle|Geurts-Giele, Willemina R|van Ravesteyn, Thomas W|Hoeksel, Johan|Meijer, Gerrit A|Te Riele, Hein|van Leeuwen, Flora E|Dinjens, Winand N|van L
PMID: 29439113
Journal: J Obstet Gynaecol Res. 2018 May;44(5):944-950.
Title: Clinicopathologic characteristics of double primary endometrial and colorectal cancers in a single institution.
Author: Lee, Hyun J|Choi, Min C|Jang, Ja-Hyun|Jung, Sang G|Park, Hyun|Joo, Won D|Kim, Tae H|Lee, Chan|Lee, Je H
PMID: 29442399
Journal: J Med Genet. 2018 Apr;55(4):240-248.
Title: Comprehensive analysis of the MLH1 promoter region in 480 patients with colorectal cancer and 1150 controls reveals new variants including one with a heritable constitutional MLH1 epimutation.
Author: Morak, Monika|Ibisler, Ayseguel|Keller, Gisela|Jessen, Ellen|Laner, Andreas|Gonzales-Fassrainer, Daniela|Locher, Melanie|Massdorf, Trisari|Nissen, Anke M|Benet-Pages, Anna|Holinski-Feder, Elke
PMID: 29472279
Journal: Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2806-2811.
Title: MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques.
Author: Brammer, David W|Gillespie, Patrick J|Tian, Mei|Young, Daniel|Raveendran, Muthuswamy|Williams, Lawrence E|Gagea, Mihai|Benavides, Fernando J|Perez, Carlos J|Broaddus, Russell R|Bernacky, Bruce J|Barnhart, Kirstin F|Alauddin, Mian M|Bhutani, Manoop S|Gibbs
PMID: 29490919
Journal: Pol Merkur Lekarski. 2018 Feb 23;44(260):45-48.
Title: [Small intestine neoplasms].
Author: Sarosiek, Tomasy|Stelmaszuk, Malgorzata
PMID: 29498365
Journal: Genes Chromosomes Cancer. 2018 Jul;57(7):350-358.
Title: Evaluation of MLH1 variants of unclear significance.
Author: Koger, Nicole|Paulsen, Lea|Lopez-Kostner, Francisco|Della Valle, Adriana|Vaccaro, Carlos Alberto|Palmero, Edenir Inez|Alvarez, Karin|Sarroca, Carlos|Neffa, Florencia|Kalfayan, Pablo German|Gonzalez, Maria Laura|Rossi, Benedito Mauro|Reis, Rui Manuel|Brieg
PMID: 29520894
Journal: Oncotarget. 2017 Nov 15;9(14):11477-11488.
Title: MBD4 frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells.
Author: Suzuki, Satoshi|Iwaizumi, Moriya|Yamada, Hidetaka|Sugiyama, Tomohiro|Hamaya, Yasushi|Furuta, Takahisa|Kanaoka, Shigeru|Sugimura, Haruhiko|Miyajima, Hiroaki|Osawa, Satoshi|Carethers, John M|Sugimoto, Ken
PMID: 29545913
Journal: Mol Med Rep. 2018 May;17(5):6942-6946.
Title: Novel MSH2 splice-site mutation in a young patient with Lynch syndrome.
Author: Liccardo, Raffaella|De Rosa, Marina|Izzo, Paola|Duraturo, Francesca
PMID: 29568967
Journal: Surg Today. 2018 Aug;48(8):810-814.
Title: Alcohol consumption and early-onset risk of colorectal cancer in Japanese patients with Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Author: Miguchi, Masashi|Hinoi, Takao|Tanakaya, Kohji|Yamaguchi, Tatsuro|Furukawa, Yoichi|Yoshida, Teruhiko|Tamura, Kazuo|Sugano, Kokichi|Ishioka, Chikashi|Matsubara, Nagahide|Tomita, Naohiro|Arai, Masami|Ishikawa, Hideki|Hirata, Keiji|Saida, Yoshihisa|Ishida, Hi
PMID: 29574523
Journal: Cancer Med. 2018 May;7(5):2078-2088.
Title: Germline MLH1, MSH2 and MSH6 variants in Brazilian patients with colorectal cancer and clinical features suggestive of Lynch Syndrome.
Author: Schneider, Naye Balzan|Pastor, Tatiane|Paula, Andre Escremim de|Achatz, Maria Isabel|Santos, Andrea Ribeiro Dos|Vianna, Fernanda Sales Luiz|Rosset, Clevia|Pinheiro, Manuela|Ashton-Prolla, Patricia|Moreira, Miguel Angelo Martins|Palmero, Edenir Inez
PMID: 29575718
Journal: S Afr J Surg. 2018 Mar;56(1):25-29.
Title: Pattern of mismatch repair protein loss and its clinicopathological correlation in colorectal cancer in North India.
Author: Kumar, A|Jain, M|Yadav, A|Kumari, N|Krishnani, N
PMID: 29638089
Journal: J Gastroenterol Hepatol. 2018 Oct;33(10):1737-1744.
Title: Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population.
Author: Cenin, Dayna R|Naber, Steffie K|Lansdorp-Vogelaar, Iris|Jenkins, Mark A|Buchanan, Daniel D|Preen, David B|Ee, Hooi C|O'Leary, Peter
PMID: 29645364
Journal: Fam Cancer. 2018 Apr 12. pii: 10.1007/s10689-018-0083-5.
Title: Unsolicited information letters to increase awareness of Lynch syndrome and familial colorectal cancer: reactions and attitudes.
Author: Petersen, Helle Vendel|Frederiksen, Birgitte Lidegaard|Lautrup, Charlotte Kvist|Lindberg, Lars Joachim|Ladelund, Steen|Nilbert, Mef
PMID: 29651783
Journal: BMC Cancer. 2018 Apr 16;18(1):433.
Title: Loss of ZG16 is associated with molecular and clinicopathological phenotypes of colorectal cancer.
Author: Meng, Hui|Li, Wencai|Boardman, Lisa A|Wang, Liang
PMID: 29661177
Journal: Mol Genet Genomic Med. 2018 Apr 17.
Title: Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.
Author: Kamiza, Abram B|Hsieh, Ling-Ling|Tang, Reiping|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|You, Jeng-Fu|Wang, Wen-Chang|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 29664240
Journal: Gut. 2018 Apr 17. pii: gutjnl-2017-315920.
Title: Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Author: Lannagan, Tamsin R M|Lee, Young K|Wang, Tongtong|Roper, Jatin|Bettington, Mark L|Fennell, Lochlan|Vrbanac, Laura|Jonavicius, Lisa|Somashekar, Roshini|Gieniec, Krystyna|Yang, Miao|Ng, Jia Q|Suzuki, Nobumi|Ichinose, Mari|Wright, Josephine A|Kobayashi, Hirok
PMID: 29666172
Journal: PLoS One. 2018 Apr 19;13(4):e0195572.
Title: Tumor development in Japanese patients with Lynch syndrome.
Author: Saita, Chiaki|Yamaguchi, Tatsuro|Horiguchi, Shin-Ichiro|Yamada, Rin|Takao, Misato|Iijima, Takeru|Wakaume, Rika|Aruga, Tomoyuki|Tabata, Taku|Koizumi, Koichi
PMID: 29672549
Journal: Virchows Arch. 2018 Aug;473(2):199-207.
Title: The prognostic impact of CDX2 correlates with the underlying mismatch repair status and BRAF mutational status but not with distant metastasis in colorectal cancer.
Author: Neumann, Jens|Heinemann, Volker|Engel, Jutta|Kirchner, Thomas|Stintzing, Sebastian
PMID: 29675807
Journal: Carcinogenesis. 2018 May 28;39(6):788-797.
Title: Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer.
Author: Pussila, Marjaana|Toronen, Petri|Einarsdottir, Elisabet|Katayama, Shintaro|Krjutskov, Kaarel|Holm, Liisa|Kere, Juha|Peltomaki, Paivi|Makinen, Markus J|Linden, Jere|Nystrom, Minna
PMID: 29701748
Journal: Langenbecks Arch Surg. 2018 Jun;403(4):443-450.
Title: Specific features of colorectal cancer in patients with metabolic syndrome: a matched case-control analysis of 772 patients.
Author: Zarzavadjian Le Bian, Alban|Denet, Christine|Tabchouri, Nicolas|Donatelli, Gianfranco|Wind, Philippe|Louvet, Christophe|Bennamoun, Mostefa|Christidis, Christos|Perniceni, Thierry|Fuks, David|Gayet, Brice
PMID: 29704123
Journal: Hum Pathol. 2018 Aug;78:125-130.
Title: Histology of colorectal adenocarcinoma with double somatic mismatch-repair mutations is indistinguishable from those caused by Lynch syndrome.
Author: Hemminger, Jessica A|Pearlman, Rachel|Haraldsdottir, Sigurdis|Knight, Deborah|Jonasson, Jon Gunnlaugur|Pritchard, Colin C|Hampel, Heather|Frankel, Wendy L
PMID: 29723603
Journal: Oncol Lett. 2018 May;15(5):7007-7013.
Title: Mismatch repair-deficient status associates with favorable prognosis of Eastern Chinese population with sporadic colorectal cancer.
Author: Gong, Qing|Zhang, Huan-Hu|Sun, Sheng-Bo|Ge, Wen-Min|Li, Yue|Zhu, Yong-Cun|Li, Le-Ping
PMID: 29725427
Journal: Histopathology. 2018 Sep;73(3):444-453.
Title: Immunohistochemical and genetic characteristics of a colorectal mucin-rich variant of traditional serrated adenoma.
Author: Hiromoto, Takafumi|Murakami, Takashi|Akazawa, Yoichi|Sasahara, Noriko|Saito, Tsuyoshi|Sakamoto, Naoto|Mitomi, Hiroyuki|Nagahara, Akihito|Yao, Takashi
PMID: 29729192
Journal: Int J Clin Oncol. 2018 May 9. pii: 10.1007/s10147-018-1282-7.
Title: Current clinical topics of Lynch syndrome.
Author: Tanakaya, Kohji
PMID: 29744602
Journal: Cancer. 2018 Aug 1;124(15):3145-3153.
Title: Universal screening of both endometrial and colon cancers increases the detection of Lynch syndrome.
Author: Adar, Tomer|Rodgers, Linda H|Shannon, Kristen M|Yoshida, Makoto|Ma, Tianle|Mattia, Anthony|Lauwers, Gregory Y|Iafrate, Anthony J|Hartford, Nicole M|Oliva, Esther|Chung, Daniel C
PMID: 29750335
Journal: Oncotarget. 2018 Apr 17;9(29):20304-20322.
Title: TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome.
Author: Gray, Phillip N|Tsai, Pei|Chen, Daniel|Wu, Sitao|Hoo, Jayne|Mu, Wenbo|Li, Bing|Vuong, Huy|Lu, Hsiao-Mei|Batth, Navanjot|Willett, Sara|Uyeda, Lisa|Shah, Swati|Gau, Chia-Ling|Umali, Monalyn|Espenschied, Carin|Janicek, Mike|Brown, Sandra|Margileth, David|Dob
PMID: 29755653
Journal: Gastroenterology. 2018 Sep;155(3):844-851.
Title: Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.
Author: Ten Broeke, Sanne W|van Bavel, Tom C|Jansen, Anne M L|Gomez-Garcia, Encarnca|Hes, Frederik J|van Hest, Liselot P|Letteboer, Tom G W|Olderode-Berends, Maran J W|Ruano, Dina|Spruijt, Liesbeth|Suerink, Manon|Tops, Carli M|van Eijk, Ronald|Morreau, Hans|van W
PMID: 29758216
Journal: Hum Genome Var. 2018 Apr 23;5:3.
Title: A novel MLH1 intronic variant in a young Japanese patient with Lynch syndrome.
Author: Kiyozumi, Yoshimi|Matsubayashi, Hiroyuki|Horiuchi, Yasue|Oishi, Takuma|Abe, Masato|Ohnami, Sumiko|Naruoka, Akane|Kusuhara, Masatoshi|Yamaguchi, Ken
PMID: 29760937
Journal: Clin Lab Med. 2018 Jun;38(2):311-342.
Title: Molecular Diagnostics in Colorectal Carcinoma: Advances and Applications for 2018.
Author: Bhalla, Amarpreet|Zulfiqar, Muhammad|Bluth, Martin H
PMID: 29776633
Journal: Transl Behav Med. 2018 May 23;8(3):450-455.
Title: Association of patient navigation with care coordination in an Lynch syndrome screening program.
Author: Miesfeldt, Susan|Feero, W Gregory|Lucas, Frances L|Rasmussen, Karen
PMID: 29800403
Journal: Clin Transl Oncol. 2018 May 25. pii: 10.1007/s12094-018-1874-8.
Title: Molecular subtypes in early colorectal cancer associated with clinical features and patient prognosis.
Author: Gil-Raga, M|Jantus-Lewintre, E|Gallach, S|Giner-Bosch, V|Frangi-Caregnato, A|Safont-Aguilera, M J|Garde-Noguera, J|Zorraquino-Pina, E|Garcia-Martinez, M|Camps-Herrero, C
PMID: 29802524
Journal: J Oncol. 2018 Apr 23;2018:3979135.
Title: Hereditary Nonpolyposis Colorectal Cancer and Cancer Syndromes: Recent Basic and Clinical Discoveries.
Author: Chen, Erbao|Xu, Xiaojing|Liu, Tianshu
PMID: 29849630
Journal: Oncol Lett. 2018 May;15(5):8053-8061.
Title: Mismatch repair protein expression in patients with stage II and III sporadic colorectal cancer.
Author: Zhao, Lihua
PMID: 29849807
Journal: Anal Cell Pathol (Amst). 2018 Apr 16;2018:1616973.
Title: Angiodrastic Chemokines in Colorectal Cancer: Clinicopathological Correlations.
Author: Emmanouil, George|Ayiomamitis, George|Zizi-Sermpetzoglou, Adamantia|Tzardi, Maria|Moursellas, Andrew|Voumvouraki, Argyro|Kouroumalis, Elias
PMID: 29850390
Journal: J Gastrointest Cancer. 2018 May 31. pii: 10.1007/s12029-018-0118-z.
Title: Detection of DNA Mismatch Repair Protein Abnormalities in Sudanese Colorectal Cancer Patients Using Immunohistochemical Methods.
Author: Zakout, Yosef Mohamed-Azzam|Lanza, Giovanni
PMID: 29850986
Journal: Oxid Med Cell Longev. 2018 Mar 22;2018:3734250.
Title: Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco-2 Cells.
Author: Zappe, Katja|Pointner, Angelika|Switzeny, Olivier J|Magnet, Ulrich|Tomeva, Elena|Heller, Jutta|Mare, George|Wagner, Karl-Heinz|Knasmueller, Siegfried|Haslberger, Alexander G
PMID: 29854080
Journal: Yonsei Med J. 2018 Jul;59(5):588-594.
Title: CpG Island Methylator Phenotype and Methylation of Wnt Pathway Genes Together Predict Survival in Patients with Colorectal Cancer.
Author: Kim, Se Hyun|Park, Kyu Hyun|Shin, Sang Joon|Lee, Kang Young|Kim, Tae Il|Kim, Nam Kyu|Rha, Sun Young|Ahn, Joong Bae
PMID: 29869456
Journal: Therap Adv Gastroenterol. 2018 May 27;11:1756284818775058.
Title: Impact of an optimized colonoscopic screening program for patients with Lynch syndrome: 6-year results of a specialized French network.
Author: Perrod, Guillaume|Samaha, Elia|Rahmi, Gabriel|Khater, Sherine|Abbes, Leila|Savale, Camille|Perkins, Geraldine|Zaanan, Aziz|Chatellier, Gilles|Malamut, Georgia|Cellier, Christophe
PMID: 29872454
Journal: Clin Cancer Res. 2018 Sep 15;24(18):4602-4611.
Title: Disruption of a -35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells.
Author: Liu, Qing|Thoms, Julie A I|Nunez, Andrea C|Huang, Yizhou|Knezevic, Kathy|Packham, Deborah|Poulos, Rebecca C|Williams, Rachel|Beck, Dominik|Hawkins, Nicholas J|Ward, Robyn L|Wong, Jason W H|Hesson, Luke B|Sloane, Mathew A|Pimanda, John E
PMID: 29898989
Journal: BMC Med Genet. 2018 Jun 22;19(1):106.
Title: A Chinese family affected by lynch syndrome caused by MLH1 mutation.
Author: Jia, Shuqin|Zhang, Meng|Sun, Yu|Yan, Hai|Zhao, Fangping|Li, Ziyu|Ji, Jiafu
PMID: 29929473
Journal: Sci Rep. 2018 Jun 21;8(1):9470.
Title: Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans.
Author: Busch, Evan L|Galanko, Joseph A|Sandler, Robert S|Goel, Ajay|Keku, Temitope O
PMID: 29930328
Journal: Am J Dermatopathol. 2018 Jun 14.
Title: Muir-Torre Syndrome: A Case Report in a Woman Without Personal Cancer History.
Author: Torre, Kristin|Ricketts, Janelle|Dadras, Soheil S
PMID: 29933315
Journal: Zhonghua Zhong Liu Za Zhi. 2018 Jun 23;40(6):433-440.
Title: [Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
Author: Yang, J|Wang, X|Zou, S M|Li, H M|Xiao, Q|Feng, Y R|Huang, Y|Feng, T|Chen, J N|Lin, D X|Li, Y X|Jin, J|Tan, W
PMID: 29936769
Journal: Clin Cancer Res. 2018 Jun 27. pii: 1078-0432.CCR-17-3713.
Title: Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers.
Author: Din, Shahida|Wong, Kim|Mueller, Mike F|Oniscu, Anca|Hewinson, James|Black, Catherine J|Miller, Martin L|Jimenez-Sanchez, Alejandro|Rabbie, Roy|Rashid, Mamunar|Satsangi, Jack|Adams, David J|Arends, Mark J
PMID: 29950348
Journal: Mod Pathol. 2018 Jun 28. pii: 10.1038/s41379-018-0094-7.
Title: Assessing colorectal cancer mismatch repair status in the modern era: a survey of current practices and re-evaluation of the role of microsatellite instability testing.
Author: Hissong, Erika|Crowe, Elizabeth P|Yantiss, Rhonda K|Chen, Yao-Tseng
PMID: 29955148
Journal: Epigenomics. 2018 Jul 2.
Title: Investigation of GHSR and GHRL methylation in colorectal cancer.
Author: Coppede, Fabio|Stoccoro, Andrea|Lazzarotti, Alessandro|Spisni, Roberto|Migliore, Lucia
PMID: 29963901
Journal: Eur J Hum Genet. 2018 Jul 2. pii: 10.1038/s41431-018-0207-2.
Title: Optimization of the diagnosis of inherited colorectal cancer using NGS and capture of exonic and intronic sequences of panel genes.
Author: Baert-Desurmont, Stephanie|Coutant, Sophie|Charbonnier, Francoise|Macquere, Pierre|Lecoquierre, Francois|Schwartz, Mathias|Blanluet, Maud|Vezain, Myriam|Lanos, Raphael|Quenez, Olivier|Bou, Jacqueline|Bouvignies, Emilie|Fourneaux, Steeve|Manase, Sandrine|V
PMID: 29967336
Journal: J Cancer Res Ther. 2018;14(4):851-855.
Title: Promoter methylation of human mutL homolog 1 and colorectal cancer risk: A meta-analysis.
Author: Shi, Bian|Chu, Junfeng|Gao, Qilong|Tian, Tongde
PMID: 29970664
Journal: Cancer Genomics Proteomics. 2018 Jul-Aug;15(4):265-271.
Title: Frequency of Mismatch Repair Protein Deficiency in a Puerto Rican Population with Colonic Adenoma and Adenocarcinoma.
Author: Reveron, Dayana|Lopez, Christian|Gutierrez, Sylvia|Sayegh, Zena E|Antonia, Teresita|Dutil, Julie|Malafa, Mokenge|Coppola, Domenico
PMID: 29976631
Journal: Oncotarget. 2018 Jun 19;9(47):28691-28701.
Title: Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients.
Author: Berardinelli, Gustavo Noriz|Scapulatempo-Neto, Cristovam|Duraes, Ronilson|Antonio de Oliveira, Marco|Guimaraes, Denise|Reis, Rui Manuel
PMID: 29983889
Journal: Appl Immunohistochem Mol Morphol. 2018 Jul 5.
Title: Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
Author: Wedden, Sarah|Miller, Keith|Frayling, Ian M|Thomas, Teresa|Chefani, Alina|Miller, Karolina|Hamblin, Angela|Taylor, Jenny C|D'Arrigo, Corrado
PMID: 29985199
Journal: Scand J Gastroenterol. 2018 Aug;53(8):972-975.
Title: The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.
Author: Halldorsson, Matthias Orn|Hauptmann, Michael|Snaebjornsson, Petur|Haraldsdottir, Kristin Huld|Aspelund, Thor|Gudmundsson, Elias Freyr|Gudnason, Vilmundur|Jonasson, Jon Gunnlaugur|Haraldsdottir, Sigurdis
PMID: 30010450
Journal: Genet Test Mol Biomarkers. 2018 Aug;22(8):492-497.
Title: The First Molecular Screening of MLH1 and MSH2 Genes in Moroccan Colorectal Cancer Patients Shows a Relatively High Mutational Prevalence.
Author: Moufid, Fatima Zahra|Bouguenouch, Laila|El Bouchikhi, Ihssane|Chbani, Laila|Iraqui Houssaini, Mohamed|Sekal, Mohamed|Belhassan, Khadija|Bennani, Bahia|Ouldim, Karim
PMID: 30044143
Journal: Anticancer Res. 2018 Aug;38(8):4847-4852.
Title: Sigmoid Colon Adenocarcinoma with Isolated Loss of PMS2 Presenting in a Patient with Synchronous Prostate Cancer with Intact MMR: Diagnosis and Analysis of the Family Pedigree.
Author: Liu, Weidong|Zhang, Dongwei|Tan, Sanda A|Liu, Xiuli|Lai, Jinping
PMID: 30061258
Journal: Gastroenterology. 2018 Jul 28. pii: S0016-5085(18)34818-2.
Title: No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies.
Author: Engel, Christoph|Vasen, Hans F|Seppala, Toni|Aretz, Stefan|Bigirwamungu-Bargeman, Marloes|de Boer, Sybrand Y|Bucksch, Karolin|Buttner, Reinhard|Feder, Elke Holinski|Holzapfel, Stefanie|Huneburg, Robert|Jacobs, Maarten A J M|Jarvinen, Heikki|Kloor, Matthia
PMID: 30063918
Journal: Gastroenterology. 2018 Jul 28. pii: S0016-5085(18)34817-0.
Title: Routine molecular analysis for Lynch syndrome among adenomas or colorectal cancer within a national screening program.
Author: Goverde, A|Wagner, A|Bruno, M J|Hofstra, R M W|Doukas, M|van der Weiden, M M|Dubbink, H J|Dinjens, W N M|Spaander, M C W
PMID: 30063919
Journal: Ann Saudi Med. 2018 Jul-Aug;38(4):251-259.
Title: Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution.
Author: Ibrahim, Tony|Saer-Ghorra, Claude|Trak-Smayra, Vivane|Nadiri, Samah|Yazbeck, Charbel|Baz, Maria|Kattan, Joseph G
PMID: 30078023
Journal: Hum Genome Var. 2018 Jun 21;5:13.
Title: A novel MLH1 mutation in a Japanese family with Lynch syndrome associated with small bowel cancer.
Author: Akizawa, Yoshika|Yamamoto, Toshiyuki|Tamura, Kazuo|Kanno, Toshiyuki|Takahashi, Nobuko|Ohki, Takeshi|Omori, Teppei|Tokushige, Katsutoshi|Yamamoto, Masakazu|Saito, Kayoko
PMID: 30083359
Journal: J Drug Target. 2018 Sep 5:1-7.
Title: Development of patient-derived orthotopic xenografts from metastatic colorectal cancer in nude mice.
Author: Roque-Lima, Bruno|Roque, Caroline Correa de Tulio Augusto|Begnami, Maria Dirlei|Peresi, Patricia|Lima, Eduardo Nobrega Pereira|Mello, Celso Abdon Lopes de|Coimbra, Felipe JoseFernandez|Chojniak, Rubens|Goss Santos, Tiago
PMID: 30088428
Journal: Sci Rep. 2018 Aug 14;8(1):12122.
Title: A cancer vaccine approach for personalized treatment of Lynch Syndrome.
Author: Majumder, Snigdha|Shah, Rakshit|Elias, Jisha|Manoharan, Malini|Shah, Priyanka|Kumari, Anjali|Chakraborty, Papia|Kode, Vasumathi|Mistry, Yogesh|Coral, Karunakaran|Mittal, Bharti|Sm, Sakthivel Murugan|Mahadevan, Lakshmi|Gupta, Ravi|Chaudhuri, Amitabha|Khann
PMID: 30108227
Journal: Genes Cancer. 2018 Mar;9(3-4):142-152.
Title: Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques.
Author: Dray, Beth K|Raveendran, Muthuswamy|Harris, R Alan|Benavides, Fernando|Gray, Stanton B|Perez, Carlos J|McArthur, Mark J|Williams, Lawrence E|Baze, Wallace B|Doddapaneni, Harsha|Muzny, Donna M|Abee, Christian R|Rogers, Jeffrey
PMID: 30108684
Journal: Gene. 2018 Nov 30;677:299-307.
Title: DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer.
Author: Sharp, Stephen P|Malizia, Robert A|Walrath, Travis|D'Souza, Shanti S|Booth, Carmen J|Kartchner, Brittany J|Lee, Edward C|Stain, Steven C|O'Connor, William Jr
PMID: 30121380
Journal: Am J Surg Pathol. 2018 Aug 24.
Title: Universal Lynch Syndrome Screening Should be Performed in All Upper Tract Urothelial Carcinomas.
Author: Ju, Jennifer Y|Mills, Anne M|Mahadevan, Mani S|Fan, Jinbo|Culp, Stephen H|Thomas, Martha H|Cathro, Helen P
PMID: 30148743
Journal: Mol Carcinog. 2018 Aug 29.
Title: EXOSC4 functions as a potential oncogene in development and progression of colorectal cancer.
Author: Pan, Yi|Tong, Joanna H M|Kang, Wei|Lung, Raymond W M|Chak, Wing Po|Chung, Lau Ying|Wu, Feng|Li, Hui|Yu, Jun|Chan, Anthony W H|To, Ka Fai
PMID: 30155936
Journal: J Clin Oncol. 2018 Aug 30:JCO2018784777.
Title: Cancer Risks for PMS2-Associated Lynch Syndrome.
Author: Ten Broeke, Sanne W|van der Klift, Heleen M|Tops, Carli M J|Aretz, Stefan|Bernstein, Inge|Buchanan, Daniel D|de la Chapelle, Albert|Capella, Gabriel|Clendenning, Mark|Engel, Christoph|Gallinger, Steven|Gomez Garcia, Encarna|Figueiredo, Jane C|Haile, Rober
PMID: 30161022
Journal: BMJ Open. 2018 Aug 30;8(8):e023102.
Title: Prevalence and clinicopathological characteristics of mismatch repair-deficient colorectal carcinoma in early onset cases as compared with late-onset cases: a retrospective cross-sectional study in Northeastern Iran.
Author: Goshayeshi, Ladan|Ghaffarzadegan, Kamran|Khooei, Alireza|Esmaeilzadeh, Abbas|Rahmani Khorram, Mahla|Mosannen Mozaffari, Hooman|Kiani, Behzad|Hoseini, Benyamin
PMID: 30166308
Journal: Mod Pathol. 2018 Aug 30. pii: 10.1038/s41379-018-0114-7.
Title: Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas.
Author: Liu, Sandy|Gnen, Mithat|Stadler, Zsofia K|Weiser, Martin R|Hechtman, Jaclyn F|Vakiani, Efsevia|Wang, Tao|Vyas, Monika|Joneja, Upasana|Al-Bayati, Moataz|Segal, Neil H|Smith, J Joshua|King, Sarah|Guercio, Shanna|Ntiamoah, Peter|Markowitz, Arnold J|Zhang, Li
PMID: 30166615
Journal: Hum Pathol. 2018 Aug 30. pii: S0046-8177(18)30336-8.
Title: Immune environment in serrated lesions of the Colon: intraepithelial lymphocyte density, PD-1, and PD-L1 expression correlate with serrated neoplasia pathway progression.
Author: Acosta-Gonzalez, Gabriel|Ouseph, Madhu|Lombardo, Kara|Lu, Shaolei|Glickman, Jonathan|Resnick, Murray
PMID: 30172913
Journal: PeerJ. 2018 Sep 11;6:e5530.
Title: DNA mismatch repair and CD133-marked cancer stem cells in colorectal carcinoma.
Author: Cheah, Phaik-Leng|Li, Jing|Looi, Lai-Meng|Teoh, Kean-Hooi|Ong, Diana Bee-Lan|Arends, Mark J
PMID: 30221090
Journal: PLoS One. 2018 Sep 26;13(9):e0203885.
Title: Novel genetic mutations detected by multigene panel are associated with hereditary colorectal cancer predisposition.
Author: Martin-Morales, Lorena|Rofes, Paula|Diaz-Rubio, Eduardo|Llovet, Patricia|Lorca, Victor|Bando, Inmaculada|Perez-Segura, Pedro|de la Hoya, Miguel|Garre, Pilar|Garcia-Barberan, Vanesa|Caldes, Trinidad
PMID: 30256826
Journal: Turk J Gastroenterol. 2018 Oct;29(6):701-704.
Title: Molecular and presymptomatic analysis of a Moroccan Lynch syndrome family revealed a novel frameshift MLH1 germline mutation.
Author: Moufid, Fatima Zahra|Bouguenouch, Laila|El Bouchikhi, Ihssane|Houssaini, Mohamed Iraqui|Ouldim, Karim
PMID: 30289396
Journal: Gynecol Oncol Rep. 2018 Sep 24;26:49-52.
Title: Mullerian carcinosarcoma in the colon of a patient with history of endometrial carcinoma: A case report and insight into possible pathogenesis.
Author: Hemedez, Claire Anne Therese|Lomme, Michele|Ruhul Quddus, M
PMID: 30294656
Journal: Asia Pac J Clin Oncol. 2018 Oct 7.
Title: Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers.
Author: Mascarenhas, Lyon|Shanley, Susan|Mitchell, Gillian|Spurdle, Amanda B|Macrae, Finlay|Pachter, Nicholas|Buchanan, Daniel D|Ward, Robyn L|Fox, Stephen|Duxbury, Elaine|Driessen, Rebecca|Boussioutas, Alex
PMID: 30294856
Journal: Indian J Pathol Microbiol. 2018 Oct-Dec;61(4):520-525.
Title: Prevalence estimation of microsatellite instability in colorectal cancers using tissue microarray based methods - A tertiary care center experience.
Author: Nayak, Sonali Susmita|Roy, Paromita|Arora, Neeraj|Arun, Indu|Roy, Manas Kumar|Banerjee, Sudeep|Mallick, Indranil|Mallath, Mohandas K
PMID: 30303141
Journal: Int J Cancer. 2018 Oct 10.
Title: From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America.
Author: Vaccaro, Carlos Alberto|Lopez-Kostner, Francisco|Valle, Adriana Della|Palmero, Edenir Inez|Rossi, Benedito Mauro|Antelo, Marina|Solano, Angela|Carraro, Dirce Maria|Forones, Nora Manoukian|Bohorquez, Mabel|Lino-Silva, Leonardo S|Buleje, Jose|Spirandelli, F
PMID: 30303536
Journal: J Cell Mol Med. 2018 Oct 16.
Title: Identification of Lynch syndrome risk variants in the Romanian population.
Author: Iordache, Paul D|Mates, Dana|Gunnarsson, Bjarni|Eggertsson, Hannes P|Sulem, Patrick|Benonisdottir, Stefania|Csiki, Irma Eva|Rascu, Stefan|Radavoi, Daniel|Ursu, Radu|Staicu, Catalin|Calota, Violeta|Voinoiu, Angelica|Jinga, Mariana|Rosoga, Gabriel|Danau, Ra
PMID: 30324682
Journal: J Clin Oncol. 2018 Oct 30:JCO1800283.
Title: Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.
Author: Latham, Alicia|Srinivasan, Preethi|Kemel, Yelena|Shia, Jinru|Bandlamudi, Chaitanya|Mandelker, Diana|Middha, Sumit|Hechtman, Jaclyn|Zehir, Ahmet|Dubard-Gault, Marianne|Tran, Christina|Stewart, Carolyn|Sheehan, Margaret|Penson, Alexander|DeLair, Deborah|Yae
PMID: 30376427
Journal: Histopathology. 2018 Oct 31.
Title: Punctate MLH1 mismatch repair immunostaining in colorectal cancer.
Author: Loughrey, Maurice B|Dunne, Philip D|Coleman, Helen G|McQuaid, Stephen|James, Jacqueline A
PMID: 30379344
Journal: Hum Pathol. 2018 Oct 28. pii: S0046-8177(18)30410-6.
Title: DNA mismatch repair deficiency but not ARID1A loss is associated with prognosis in small intestinal adenocarcinoma.
Author: Gonzalez, Ivan|Goyal, Bella|Xia, Michelle D|Pai, Reetesh K|Ma, Changqing
PMID: 30381262
Journal: J Pathol Clin Res. 2018 Nov 1.
Title: Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation.
Author: McCarthy, Aoife J|Capo-Chichi, Jose-Mario|Spence, Tara|Grenier, Sylvie|Stockley, Tracy|Kamel-Reid, Suzanne|Serra, Stefano|Sabatini, Peter|Chetty, Runjan
PMID: 30387329