Primary Site >> Esophagus Cancer

Gene >> MGMT

Journal: Carcinogenesis. 1992 Sep;13(9):1503-7.
Title: O6-methylguanine-DNA methyltransferase activity in human tumors.
Author: Chen, J M|Zhang, Y P|Wang, C|Sun, Y|Fujimoto, J|Ikenaga, M
PMID: 1394831
Journal: Int J Cancer. 1997 May 29;71(5):719-23.
Title: Mutations of O6-methylguanine-DNA methyltransferase gene in esophageal cancer tissues from Northern China.
Author: Wang, L|Zhu, D|Zhang, C|Mao, X|Wang, G|Mitra, S|Li, B F|Wang, X|Wu, M
PMID: 9180136
Journal: Oncol Rep. 2003 Sep-Oct;10(5):1615-23.
Title: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Author: Xing, Deyin|Tan, Wen|Lin, Dongxin
PMID: 12883749
Journal: Cancer Res. 2003 Nov 15;63(22):7563-70.
Title: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Author: Fang, Ming Zhu|Wang, Yimin|Ai, Ni|Hou, Zhe|Sun, Yi|Lu, Hong|Welsh, William|Yang, Chung S
PMID: 14633667
Journal: Clin Cancer Res. 2004 Jul 1;10(13):4444-9.
Title: Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy.
Author: Pellise, Maria|Castells, Antoni|Gines, Angels|Agrelo, Ruben|Sole, Manel|Castellvi-Bel, Sergi|Fernandez-Esparrach, Gloria|Llach, Josep|Esteller, Manel|Bordas, Josep M|Pique, Josep M
PMID: 15240535
Journal: Cancer Lett. 2004 Sep 30;213(2):195-202.
Title: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison.
Author: Sepehr, Alireza|Kamangar, Farin|Abnet, Christian C|Fahimi, Saman|Pourshams, Akram|Poustchi, Hossein|Zeinali, Sirous|Sotoudeh, Masood|Islami, Farhad|Nasrollahzadeh, Dariush|Malekzadeh, Reza|Taylor, Philip R|Dawsey, Sanford M
PMID: 15327835
Journal: Clin Gastroenterol Hepatol. 2006 Jun;4(6):701-8. Epub 2006 May 4.
Title: Promoter methylation and response to chemotherapy and radiation in esophageal cancer.
Author: Hamilton, James P|Sato, Fumiaki|Greenwald, Bruce D|Suntharalingam, Mohan|Krasna, Mark J|Edelman, Martin J|Doyle, Austin|Berki, Agnes T|Abraham, John M|Mori, Yuriko|Kan, Takatsugu|Mantzur, Carmit|Paun, Bogdan|Wang, Suna|Ito, Tetsuo|Jin, Zhe|Meltzer, Stephe
PMID: 16678495
Journal: Ai Zheng. 2008 Dec;27(12):1256-62.
Title: [Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma].
Author: Xue, Heng-Chuan|Wang, Jian-Ming|Xu, Biao|Guo, Guo-Ping|Hua, Zhao-Lai|Zhou, Qin|Zhu, Zong-Hai|Ma, Zhen-Kai|Gao, Jie
PMID: 19079989
Journal: Cancer Lett. 2009 Mar 8;275(1):117-26.
Title: Silencing of MGMT expression by promoter hypermethylation in the metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus.
Author: Kuester, Doerthe|El-Rifai, Wa'el|Peng, DunFa|Ruemmele, Petra|Kroeckel, Ivonne|Peters, Brigitte|Moskaluk, Christopher A|Stolte, Manfred|Monkemuller, Klaus|Meyer, Frank|Schulz, Hans-Ulrich|Hartmann, Arndt|Roessner, Albert|Schneider-Stock, Regine
PMID: 19027227
Journal: Dig Dis Sci. 2011 Oct;56(10):2992-3004.
Title: Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer.
Author: Ling, Zhi-Qiang|Li, Pei|Ge, Ming-Hua|Hu, Fu-Jun|Fang, Xian-Hua|Dong, Zi-Min|Mao, Wei-Min
PMID: 21674174
Journal: DNA Cell Biol. 2012 May;31(5):856-66.
Title: Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein.
Author: Su, Yaoyao|Liu, Ran|Sheng, JingYi|Liu, Hui|Wang, Yi|Pan, Enchun|Guo, Wei|Pu, Yuepu|Zhang, Juan|Liang, Geyu|Tang, Derong|Yin, Lihong
PMID: 22196440
Journal: Asian Pac J Cancer Prev. 2012;13(7):3047-52.
Title: Lack of influence of MGMT codon Leu84Phe and codon Ileu143Val polymorphisms on esophageal cancer risk in the Kashmir Valley.
Author: Shah, Mohd A|Shaff, Sheikh M|Lone, Ghulam Nabi|Jan, Syed Mudassar
PMID: 22994708
Journal: J Carcinog. 2013 Oct 28;12:20.
Title: O-6-methylguanine-deoxyribonucleic acid methyltransferase methylation enhances response to temozolomide treatment in esophageal cancer.
Author: Hasina, Rifat|Surati, Mosmi|Kawada, Ichiro|Arif, Qudsia|Carey, George B|Kanteti, Rajani|Husain, Aliya N|Ferguson, Mark K|Vokes, Everett E|Villaflor, Victoria M|Salgia, Ravi
PMID: 24319345
Journal: Int J Health Sci (Qassim). 2013 Nov;7(3):277-84.
Title: Splice site and Germline variations of the MGMT gene in Esophageal cancer from Kashmir Valley: India.
Author: Shah, Mohd Amin|Shaffi, Sheikh M|Lone, Ghulam Nabi|Jan, Syed Mudassar
PMID: 24533020
Journal: Tumour Biol. 2013 Oct;34(5):3227-37.
Title: The polymorphisms in the MGMT gene and the risk of cancer: a meta-analysis.
Author: Du, Liang|Wang, Haichuan|Xiong, Tianyuan|Ma, Yaxian|Yang, Jiqiao|Huang, Jichong|Zeng, Dong|Wang, Xiaoze|Huang, He|Huang, Jin
PMID: 23760981
Journal: Mol Cancer Ther. 2013 May;12(5):809-18.
Title: A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter.
Author: Hochhauser, Daniel|Glynne-Jones, Rob|Potter, Vanessa|Gravalos, Cristina|Doyle, Thomas J|Pathiraja, Kumudu|Zhang, Qing|Zhang, Ling|Sausville, Edward A
PMID: 23443801
Journal: Mol Carcinog. 2014 Mar;53(3):201-10.
Title: Tumor-associated mutations in O(6) -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.
Author: Lamb, Kristy L|Liu, Yanfeng|Ishiguro, Kimiko|Kwon, Youngho|Paquet, Nicolas|Sartorelli, Alan C|Sung, Patrick|Rockwell, Sara|Sweasy, Joann B
PMID: 23065697
Journal: Am J Clin Oncol. 2014 Oct;37(5):444-9.
Title: Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
Author: Jeyapalan, Suriya|Boxerman, Jerrold|Donahue, John|Goldman, Marc|Kinsella, Timothy|Dipetrillo, Thomas|Evans, Devon|Elinzano, Heinrich|Constantinou, Maria|Stopa, Edward|Puthawala, Yakub|Cielo, Deus|Santaniello, Alyson|Oyelese, Adetokunbo|Mantripragada, Kaly
PMID: 23388562
Journal: Med Oncol. 2014 Feb;31(2):784.
Title: Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma.
Author: Su, Yaoyao|Yin, Lihong|Liu, Ran|Sheng, Jingyi|Yang, Miao|Wang, Yi|Pan, Enchun|Guo, Wei|Pu, Yuepu|Zhang, Juan|Liang, Geyu
PMID: 24366688
Journal: Tumour Biol. 2014 Oct;35(10):10085-93.
Title: Abnormal MGMT promoter methylation may contribute to the risk of esophageal cancer: a meta-analysis of cohort studies.
Author: Zhao, Jia-Jun|Li, Hong-Yu|Wang, Di|Yao, Hui|Sun, Da-Wei
PMID: 25015189
Journal: Pathol Res Pract. 2014 Oct;210(10):656-61.
Title: ERCC1 expression and tumor regression predict survival in esophageal squamous cell carcinoma patients receiving combined trimodality therapy.
Author: Ge, Hong|Lu, Yufei|Chen, Yongshun|Zheng, Xiaoli|Wang, Wen|Yu, Jinming
PMID: 25042384
Journal: Asian Pac J Cancer Prev. 2014;15(22):9955-60.
Title: Promoter methylation of MGMT gene in serum of patients with esophageal squamous cell carcinoma in North East India.
Author: Das, Mandakini|Sharma, Santanu Kumar|Sekhon, Gaganpreet Singh|Saikia, Bhaskar Jyoti|Mahanta, Jagadish|Phukan, Rup Kumar
PMID: 25520135
Journal: Cancer Biol Ther. 2015;16(5):764-9.
Title: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options.
Author: Miura, John T|Xiu, Joanne|Thomas, James|George, Ben|Carron, Benjamin R|Tsai, Susan|Johnston, Fabian M|Turaga, Kiran K|Gamblin, T Clark
PMID: 25778705
Journal: Clin Epigenetics. 2016 Apr 22;8:43.
Title: The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma.
Author: Ma, Kai|Cao, Baoping|Guo, Mingzhou
PMID: 27110300
Journal: Tumour Biol. 2017 May;39(5):1010428317701630.
Title: Alteration in the expression of MGMT and RUNX3 due to non-CpG promoter methylation and their correlation with different risk factors in esophageal cancer patients.
Author: Saikia, Snigdha|Rehman, Asad Ur|Barooah, Prajjalendra|Sarmah, Preeti|Bhattacharyya, Mallika|Deka, Muktanjalee|Deka, Manab|Goswami, Bhabadev|Husain, Syed Akhtar|Medhi, Subhash
PMID: 28468586
Journal: Tumour Biol. 2017 Jun;39(6):1010428317705770.
Title: Decreased expression of MGMT in correlation with aberrant DNA methylation in esophageal cancer patients from North India.
Author: Rehman, Asad Ur|Saikia, Snigdha|Iqbal, Mohammad Askandar|Ahmad, Istaq|Sadaf|Anees, Afzal|Aravinda, P S|Mishra, Pramod Kumar|Hedau, Suresh|Saluja, Sundeep Singh|Medhi, Subhash|Husain, Syed Akhtar
PMID: 28621225
Journal: Dig Dis. 2018;36(2):89-97.
Title: Clinical Significance of O-6-Methylguanine-DNA-Methyltransferase Promoter Methylation in Patients with Esophageal Carcinoma: A Systematic Meta-Analysis.
Author: Zhang, Yan|Tong, Ti
PMID: 29258097
Journal: J Cancer. 2018 Jul 30;9(16):2865-2875.
Title: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
Author: Dong, Yin|Yi, Xu|Yujie, Zhen|Huixia, Zhang|Yan, Chen
PMID: 30123355