Primary Site >> Esophagus Cancer

Gene >> MGMT

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Ref: O6-methylguanine-DNA methyltransferase activity in human tumors.
PMID: 1394831
 Ref: Mutations of O6-methylguanine-DNA methyltransferase gene in esophageal cancer tissues from Northern China.
PMID: 9180136
 Ref: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
PMID: 12883749
Ref: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
PMID: 14633667
 Ref: Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy.
PMID: 15240535
Ref: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison.
PMID: 15327835
 Ref: Promoter methylation and response to chemotherapy and radiation in esophageal cancer.
PMID: 16678495
 Ref: [Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma].
PMID: 19079989
 Ref: Silencing of MGMT expression by promoter hypermethylation in the metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus.
PMID: 19027227
 Ref: Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer.
PMID: 21674174
 Ref: Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein.
PMID: 22196440
Ref: Lack of influence of MGMT codon Leu84Phe and codon Ileu143Val polymorphisms on esophageal cancer risk in the Kashmir Valley.
PMID: 22994708
 Ref: A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter.
PMID: 23443801
Ref: The polymorphisms in the MGMT gene and the risk of cancer: a meta-analysis.
PMID: 23760981
Ref: O-6-methylguanine-deoxyribonucleic acid methyltransferase methylation enhances response to temozolomide treatment in esophageal cancer.
PMID: 24319345
Ref: Splice site and Germline variations of the MGMT gene in Esophageal cancer from Kashmir Valley: India.
PMID: 24533020
 Ref: Tumor-associated mutations in O(6) -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.
PMID: 23065697
Ref: Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
PMID: 23388562
Ref: Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma.
PMID: 24366688
Ref: Abnormal MGMT promoter methylation may contribute to the risk of esophageal cancer: a meta-analysis of cohort studies.
PMID: 25015189
Ref: ERCC1 expression and tumor regression predict survival in esophageal squamous cell carcinoma patients receiving combined trimodality therapy.
PMID: 25042384
Ref: Promoter methylation of MGMT gene in serum of patients with esophageal squamous cell carcinoma in North East India.
PMID: 25520135
 Ref: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options.
PMID: 25778705
 Ref: The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma.
PMID: 27110300
 Ref: Alteration in the expression of MGMT and RUNX3 due to non-CpG promoter methylation and their correlation with different risk factors in esophageal cancer patients.
PMID: 28468586
Ref: Decreased expression of MGMT in correlation with aberrant DNA methylation in esophageal cancer patients from North India.
PMID: 28621225
 Ref: Clinical Significance of O-6-Methylguanine-DNA-Methyltransferase Promoter Methylation in Patients with Esophageal Carcinoma: A Systematic Meta-Analysis.
PMID: 29258097
Ref: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
PMID: 30123355