Literatures

Primary Site >> Colorectal Cancer

Gene >> MGMT

1.
Journal:	Carcinogenesis. 1986 Sep;7(9):1603-6.
Title:	Transfection of DNA from a chloroethylnitrosourea-resistant tumor cell line (MER+) to a sensitive tumor cell line (MER-) results in a tumor cell line resistant to MNNG and CNU that has increased O-6-methylguanine-DNA methyltransferase levels and reduced l
Author:	Yarosh, D B\|Barnes, D\|Erickson, L C
PMID:	3742731

2.
Journal:	Carcinogenesis. 1992 Sep;13(9):1503-7.
Title:	O6-methylguanine-DNA methyltransferase activity in human tumors.
Author:	Chen, J M\|Zhang, Y P\|Wang, C\|Sun, Y\|Fujimoto, J\|Ikenaga, M
PMID:	1394831

3.
Journal:	Biochemistry. 1992 Sep 1;31(34):7998-8008.
Title:	Incision at O6-methylguanine:thymine mispairs in DNA by extracts of human cells.
Author:	Sibghat-Ullah\|Day, R S 3rd
PMID:	1510986

4.
Journal:	Cancer Res. 1993 Sep 15;53(18):4281-6.
Title:	Prolonged depletion of O6-methylguanine DNA methyltransferase activity following exposure to O6-benzylguanine with or without streptozotocin enhances 1,3-bis(2-chloroethyl)-1-nitrosourea sensitivity in vitro.
Author:	Marathi, U K\|Kroes, R A\|Dolan, M E\|Erickson, L C
PMID:	8364924

5.
Journal:	Cancer Res. 1994 Aug 15;54(16):4371-5.
Title:	Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity.
Author:	Marathi, U K\|Dolan, M E\|Erickson, L C
PMID:	8044784

6.
Journal:	Clin Cancer Res. 1995 May;1(5):519-25.
Title:	Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer.
Author:	Gerson, S L\|Allay, E\|Vitantonio, K\|Dumenco, L L
PMID:	9816011

7.
Journal:	Cancer Detect Prev. 1996;20(2):130-6.
Title:	Activity of the DNA repair protein O6-methylguanine-DNA methyltransferase in human tumor and corresponding normal tissue.
Author:	Preuss, I\|Haas, S\|Eichhorn, U\|Eberhagen, I\|Kaufmann, M\|Beck, T\|Eibl, R H\|Dall, P\|Bauknecht, T\|Hengstler, J\|Wittig, B M\|Dippold, W\|Kaina, B
PMID:	8706038

8.
Journal:	Cancer Res. 1997 Nov 1;57(21):4817-23.
Title:	O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
Author:	Phillips, W P Jr\|Willson, J K\|Markowitz, S D\|Zborowska, E\|Zaidi, N H\|Liu, L\|Gordon, N H\|Gerson, S L
PMID:	9354444

9.
Journal:	Cancer Res. 1999 Feb 15;59(4):793-7.
Title:	Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
Author:	Esteller, M\|Hamilton, S R\|Burger, P C\|Baylin, S B\|Herman, J G
PMID:	10029064

10.
Journal:	Mol Carcinog. 1999 Feb;24(2):90-8.
Title:	A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers.
Author:	Herfarth, K K\|Brent, T P\|Danam, R P\|Remack, J S\|Kodner, I J\|Wells, S A Jr\|Goodfellow, P J
PMID:	10078936

11.
Journal:	Hum Gene Ther. 1999 Apr 10;10(6):1021-30.
Title:	DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts.
Author:	Koc, O N\|Reese, J S\|Davis, B M\|Liu, L\|Majczenko, K J\|Gerson, S L
PMID:	10223735

12.
Journal:	Cancer Res. 2000 May 1;60(9):2368-71.
Title:	Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Author:	Esteller, M\|Toyota, M\|Sanchez-Cespedes, M\|Capella, G\|Peinado, M A\|Watkins, D N\|Issa, J P\|Sidransky, D\|Baylin, S B\|Herman, J G
PMID:	10811111

13.
Journal:	Cancer Epidemiol Biomarkers Prev. 2000 Aug;9(8):819-26.
Title:	Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation.
Author:	Hong, M Y\|Lupton, J R\|Morris, J S\|Wang, N\|Carroll, R J\|Davidson, L A\|Elder, R H\|Chapkin, R S
PMID:	10952099

14.
Journal:	Cancer Res. 2001 Feb 1;61(3):827-30.
Title:	Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability.
Author:	Whitehall, V L\|Walsh, M D\|Young, J\|Leggett, B A\|Jass, J R
PMID:	11221863

15.
Journal:	Nucleic Acids Res. 2001 Jun 1;29(11):2409-17.
Title:	Initiation of strand incision at G:T and O(6)-methylguanine:T base mismatches in DNA by human cell extracts.
Author:	Lari, S U\|Day, R S\|Dobler, K\|Paterson, M C
PMID:	11376160

16.
Journal:	Cancer Res. 2001 Jun 15;61(12):4689-92.
Title:	Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
Author:	Esteller, M\|Risques, R A\|Toyota, M\|Capella, G\|Moreno, V\|Peinado, M A\|Baylin, S B\|Herman, J G
PMID:	11406538

17.
Journal:	Cancer Res. 2001 Nov 15;61(22):8113-7.
Title:	O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
Author:	Wolf, P\|Hu, Y C\|Doffek, K\|Sidransky, D\|Ahrendt, S A
PMID:	11719438

18.
Journal:	Hum Mol Genet. 2001 Dec 15;10(26):3001-7.
Title:	DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Author:	Esteller, M\|Fraga, M F\|Guo, M\|Garcia-Foncillas, J\|Hedenfalk, I\|Godwin, A K\|Trojan, J\|Vaurs-Barriere, C\|Bignon, Y J\|Ramus, S\|Benitez, J\|Caldes, T\|Akiyama, Y\|Yuasa, Y\|Launonen, V\|Canal, M J\|Rodriguez, R\|Capella, G\|Peinado, M A\|Borg, A\|Aaltonen, L A\|Ponder,
PMID:	11751682

19.
Journal:	Ann Surg Oncol. 2001 Dec;8(10):807-16.
Title:	Expression and prognostic significance of O6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers.
Author:	Matsukura, S\|Miyazaki, K\|Yakushiji, H\|Ogawa, A\|Harimaya, K\|Nakabeppu, Y\|Sekiguchi, M
PMID:	11776495

20.
Journal:	Eur J Cancer. 2002 May;38(7):858-66.
Title:	Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.
Author:	Jass, J R\|Walsh, M D\|Barker, M\|Simms, L A\|Young, J\|Leggett, B A
PMID:	11978509

21.
Journal:	Cancer Res. 2002 Jun 1;62(11):3070-6.
Title:	Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Author:	Liu, Lili\|Schwartz, Stuart\|Davis, Brian M\|Gerson, Stanton L
PMID:	12036916

22.
Journal:	Gastroenterology. 2002 Sep;123(3):862-76.
Title:	Emerging concepts in colorectal neoplasia.
Author:	Jass, Jeremy R\|Whitehall, Vicki L J\|Young, Joanne\|Leggett, Barbara A
PMID:	12198712

23.
Journal:	Clin Cancer Res. 2002 Sep;8(9):2985-91.
Title:	Base excision repair as a therapeutic target in colon cancer.
Author:	Liu, Lili\|Nakatsuru, Yoko\|Gerson, Stanton L
PMID:	12231545

24.
Journal:	Oncology. 2002;63(4):393-7.
Title:	Heterogeneity of O(6)-alkylguanine-DNA alkyltransferase activity in colorectal cancer: implications for treatment.
Author:	Lees, Nicholas P\|Harrison, Kathryn L\|Hill, Elizabeth\|Hall, C Nicholas\|Povey, Andrew C\|Margison, Geoffrey P
PMID:	12417795

25.
Journal:	J Nutr. 2002 Nov;132(11 Suppl):3518S-3521S.
Title:	DNA alkylation and repair in the large bowel: animal and human studies.
Author:	Povey, Andrew C\|Badawi, Alaa F\|Cooper, Donald P\|Hall, C Nicholas\|Harrison, Kathryn L\|Jackson, Peta E\|Lees, Nicholas P\|O'Connor, Peter J\|Margison, Geoffrey P
PMID:	12421880

26.
Journal:	Mol Cell Biol. 2003 Jan;23(1):206-15.
Title:	Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
Author:	Kondo, Yutaka\|Shen, LanLan\|Issa, Jean-Pierre J
PMID:	12482974

27.
Journal:	Mutat Res. 2003 Jan 28;522(1-2):57-68.
Title:	Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver--comparison with phase II xenobiotic metabolism.
Author:	Huber, Wolfgang W\|Scharf, Gerlinde\|Nagel, Georg\|Prustomersky, Sonja\|Schulte-Hermann, Rolf\|Kaina, Bernd
PMID:	12517412

28.
Journal:	Carcinogenesis. 2003 Mar;24(3):527-33.
Title:	Associations between tissue-specific DNA alkylation, DNA repair and cell proliferation in the colon and colon tumour yield in mice treated with 1,2-dimethylhydrazine.
Author:	Jackson, Peta E\|O'Connor, Peter J\|Cooper, Donald P\|Margison, Geoffrey P\|Povey, Andrew C
PMID:	12663514

29.
Journal:	Mol Carcinog. 2003 May;37(1):32-8.
Title:	Alteration of O6-methylguanine-DNA methyltransferase in colorectal neoplasms in sporadic and familial adenomatous polyposis patients.
Author:	Kim, Sun Hee\|Bae, Soo In\|Lee, Hye Seung\|Kim, Woo Ho
PMID:	12720298

30.
Journal:	Cancer Res. 2003 Jun 15;63(12):3133-7.
Title:	Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Author:	van Engeland, Manon\|Weijenberg, Matty P\|Roemen, Guido M J M\|Brink, Mirian\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van den Brandt, Piet A\|Baylin, Stephen B\|de Goeij, Anton F P M\|Herman, James G
PMID:	12810640

31.
Journal:	Virchows Arch. 2003 Oct;443(4):518-23.
Title:	The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis.
Author:	Matsumura, Shunji\|Oue, Naohide\|Ito, Reiko\|Nakayama, Hirofumi\|Kitadai, Yasuhiko\|Yokozaki, Hiroshi\|Chayama, Kazuaki\|Yasui, Wataru
PMID:	12920593

32.
Journal:	Clin Cancer Res. 2003 Nov 1;9(14):5306-12.
Title:	Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases.
Author:	Nagasaka, Takeshi\|Sharp, Gerald B\|Notohara, Kenji\|Kambara, Takeshi\|Sasamoto, Hiromi\|Isozaki, Hiroshi\|MacPhee, Donald G\|Jass, Jeremy R\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	14614014

33.
Journal:	Cancer Res. 2003 Nov 15;63(22):7563-70.
Title:	Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Author:	Fang, Ming Zhu\|Wang, Yimin\|Ai, Ni\|Hou, Zhe\|Sun, Yi\|Lu, Hong\|Welsh, William\|Yang, Chung S
PMID:	14633667

34.
Journal:	Mol Diagn. 2003;7(3-4):201-7.
Title:	Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood.
Author:	Sabbioni, Silvia\|Miotto, Elena\|Veronese, Angelo\|Sattin, Elisa\|Gramantieri, Laura\|Bolondi, Luigi\|Calin, George A\|Gafa, Roberta\|Lanza, Giovanni\|Carli, Giuliano\|Ferrazzi, Eros\|Feo, Carlo\|Liboni, Alberto\|Gullini, Sergio\|Negrini, Massimo
PMID:	15068392

35.
Journal:	Gut. 2004 Apr;53(4):573-80.
Title:	Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.
Author:	Wynter, C V A\|Walsh, M D\|Higuchi, T\|Leggett, B A\|Young, J\|Jass, J R
PMID:	15016754

36.
Journal:	Lab Invest. 2004 Jul;84(7):884-93.
Title:	Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.
Author:	Lee, Sun\|Hwang, Kyu Sang\|Lee, Hyeon Joo\|Kim, Jung-Sun\|Kang, Gyeong Hoon
PMID:	15122305

37.
Journal:	Clin Cancer Res. 2004 Jul 1;10(13):4444-9.
Title:	Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy.
Author:	Pellise, Maria\|Castells, Antoni\|Gines, Angels\|Agrelo, Ruben\|Sole, Manel\|Castellvi-Bel, Sergi\|Fernandez-Esparrach, Gloria\|Llach, Josep\|Esteller, Manel\|Bordas, Josep M\|Pique, Josep M
PMID:	15240535

38.
Journal:	Fam Cancer. 2004;3(2):101-7.
Title:	Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Author:	McGivern, A\|Wynter, C V A\|Whitehall, V L J\|Kambara, T\|Spring, K J\|Walsh, M D\|Barker, M A\|Arnold, S\|Simms, L A\|Leggett, B A\|Young, J\|Jass, J R
PMID:	15340260

39.
Journal:	Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1495-501.
Title:	Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer.
Author:	Belshaw, Nigel J\|Elliott, Giles O\|Williams, Elizabeth A\|Bradburn, David M\|Mills, Sarah J\|Mathers, John C\|Johnson, Ian T
PMID:	15342451

40.
Journal:	J Exp Clin Cancer Res. 2004 Jun;23(2):317-23.
Title:	Repression of MLH1 and MGMT genes in colon mucosa adjacent to implanted cancer in athymic mouse.
Author:	Kuniyasu, H\|Sasaki, T\|Sasahira, T\|Chihara, Y\|Ohmori, H
PMID:	15354418

41.
Journal:	Int J Cancer. 2004 Dec 10;112(5):846-53.
Title:	Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.
Author:	Bai, Alfa H C\|Tong, Joanna H M\|To, Ka-Fai\|Chan, Michael W Y\|Man, Ellen P S\|Lo, Kwok-Wai\|Lee, Janet F Y\|Sung, Joseph J Y\|Leung, Wai K
PMID:	15386372

42.
Journal:	Mol Cancer. 2004 Oct 11;3:28.
Title:	A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.
Author:	Lind, Guro E\|Thorstensen, Lin\|Lovig, Tone\|Meling, Gunn I\|Hamelin, Richard\|Rognum, Torleiv O\|Esteller, Manel\|Lothe, Ragnhild A
PMID:	15476557

43.
Journal:	World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title:	Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author:	Xu, Xiao-Li\|Yu, Jian\|Zhang, Hong-Yu\|Sun, Meng-Hong\|Gu, Jun\|Du, Xiang\|Shi, Da-Ren\|Wang, Peng\|Yang, Zhen-Hua\|Zhu, Jing-De
PMID:	15526363

44.
Journal:	J Clin Oncol. 2004 Nov 15;22(22):4584-94.
Title:	Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Author:	Nagasaka, Takeshi\|Sasamoto, Hiromi\|Notohara, Kenji\|Cullings, Harry M\|Takeda, Masanori\|Kimura, Keigo\|Kambara, Takeshi\|MacPhee, Donald G\|Young, Joanne\|Leggett, Barbara A\|Jass, Jeremy R\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	15542810

45.
Journal:	Mod Pathol. 2005 Feb;18(2):170-8.
Title:	Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author:	Dong, Seung M\|Lee, Eui J\|Jeon, Eun S\|Park, Cheol K\|Kim, Kyoung-Mee
PMID:	15389252

46.
Journal:	Oncol Rep. 2005 Feb;13(2):325-8.
Title:	Development and application of a multiplex PCR procedure for the detection of DNA methylation in colorectal cancer.
Author:	Anacleto, Charles\|Rossi, Benedito\|Lopes, Ademar\|Soares, Fernando A\|Rocha, Jose Claudio C\|Caballero, Otavia\|Camargo, Anamaria A\|Simpson, Andrew J G\|Pena, Sergio D J
PMID:	15643519

47.
Journal:	Clin Cancer Res. 2005 Feb 1;11(3):1203-9.
Title:	Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps.
Author:	Petko, Zsolt\|Ghiassi, Mahan\|Shuber, Anthony\|Gorham, Janice\|Smalley, Walter\|Washington, M Kay\|Schultenover, Stephen\|Gautam, Shiva\|Markowitz, Sanford D\|Grady, William M
PMID:	15709190

48.
Journal:	Hum Pathol. 2005 Jan;36(1):101-11.
Title:	Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon.
Author:	Oh, Kirstine\|Redston, Mark\|Odze, Robert D
PMID:	15712188

49.
Journal:	Nucleic Acids Res. 2005 Mar 10;33(5):e46.
Title:	Methylation profiles of genes utilizing newly developed CpG island methylation microarray on colorectal cancer patients.
Author:	Kimura, Naoki\|Nagasaka, Takeshi\|Murakami, Jun\|Sasamoto, Hiromi\|Murakami, Masahiro\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	15760842

50.
Journal:	Carcinogenesis. 2005 Jun;26(6):1152-6. Epub 2005 Mar 10.
Title:	CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.
Author:	Brandes, Johann C\|van Engeland, Manon\|Wouters, Kim A D\|Weijenberg, Matty P\|Herman, James G
PMID:	15760919

51.
Journal:	Am J Surg Pathol. 2005 Apr;29(4):429-36.
Title:	Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation.
Author:	Chirieac, Lucian R\|Shen, Lanlan\|Catalano, Paul J\|Issa, Jean-Pierre\|Hamilton, Stanley R
PMID:	15767794

52.
Journal:	J Clin Oncol. 2005 Apr 1;23(10):2318-24.
Title:	Low microsatellite instability is associated with poor prognosis in stage C colon cancer.
Author:	Kohonen-Corish, Maija R J\|Daniel, Joseph J\|Chan, Charles\|Lin, Betty P C\|Kwun, Sun Young\|Dent, Owen F\|Dhillon, Varinderpal S\|Trent, Ronald J A\|Chapuis, Pierre H\|Bokey, E Leslie
PMID:	15800322

53.
Journal:	World J Gastroenterol. 2005 Apr 7;11(13):2022-5.
Title:	Hypermethylation of CpG island in O6-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor.
Author:	Qi, Jian\|Zhu, You-Qing\|Huang, Mei-Fang\|Yang, Dong
PMID:	15800999

54.
Journal:	Int J Oncol. 2005 Jun;26(6):1653-61.
Title:	Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest.
Author:	Sato, Ken\|Kitajima, Yoshihiko\|Kohya, Naohiko\|Miyoshi, Atsushi\|Koga, Yasuo\|Miyazaki, Kohji
PMID:	15870882

55.
Journal:	Gut. 2005 Jun;54(6):797-802.
Title:	O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.
Author:	Halford, S\|Rowan, A\|Sawyer, E\|Talbot, I\|Tomlinson, I
PMID:	15888787

56.
Journal:	Neoplasia. 2005 Apr;7(4):331-5.
Title:	Colorectal cancer "methylator phenotype": fact or artifact?
Author:	Anacleto, Charles\|Leopoldino, Andreia M\|Rossi, Benedito\|Soares, Fernando A\|Lopes, Ademar\|Rocha, Jose Claudio C\|Caballero, Otavia\|Camargo, Anamaria A\|Simpson, Andrew J G\|Pena, Sergio D J
PMID:	15967110

57.
Journal:	Nat Clin Pract Oncol. 2005 Aug;2(8):398-405.
Title:	Serrated adenoma of the colorectum and the DNA-methylator phenotype.
Author:	Jass, Jeremy R
PMID:	16130936

58.
Journal:	J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8.
Title:	MGMT promoter methylation and field defect in sporadic colorectal cancer.
Author:	Shen, Lanlan\|Kondo, Yutaka\|Rosner, Gary L\|Xiao, Lianchun\|Hernandez, Natalie Supunpong\|Vilaythong, Jill\|Houlihan, P Scott\|Krouse, Robert S\|Prasad, Anil R\|Einspahr, Janine G\|Buckmeier, Julie\|Alberts, David S\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	16174854

59.
Journal:	Biochem Biophys Res Commun. 2005 Dec 2;337(4):1176-84. Epub 2005 Oct 6.
Title:	Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry.
Author:	Niture, Suryakant K\|Doneanu, Catalin E\|Velu, Chinavenmeni S\|Bailey, Nathan I\|Srivenugopal, Kalkunte S
PMID:	16226712

60.
Journal:	J Nippon Med Sch. 2005 Oct;72(5):270-7.
Title:	Hypermethylation of the putative tumor-suppressor genes DCC, p51/63 and O6-methylguanine-DNA methyltransferase (MGMT) and loss of their expressions in cell lines of hematological malignancies.
Author:	Nakayama, Kazutaka\|Inokuchi, Koiti\|Dan, Kazuo
PMID:	16247226

61.
Journal:	Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2501-8.
Title:	DNA repair polymorphisms and risk of colorectal adenomatous or hyperplastic polyps.
Author:	Bigler, Jeannette\|Ulrich, Cornelia M\|Kawashima, Toana\|Whitton, John\|Potter, John D
PMID:	16284370

62.
Journal:	Anticancer Res. 2005 Nov-Dec;25(6B):4021-8.
Title:	The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
Author:	Sato, Ken\|Kitajima, Yoshihiko\|Koga, Yasuo\|Miyazaki, Kohji
PMID:	16309194

63.
Journal:	J Gastroenterol Hepatol. 2005 Dec;20(12):1920-6.
Title:	CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.
Author:	Kim, Hee Cheol\|Roh, Sun Ae\|Ga, In Hwa\|Kim, Jung-Sun\|Yu, Chang Sik\|Kim, Jin Cheon
PMID:	16336454

64.
Journal:	Mod Pathol. 2006 Jan;19(1):59-68.
Title:	Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Cantor, Mami\|Namgyal, Chungdak\|Kawasaki, Takako\|Kirkner, Gregory\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Fuchs, Charles S
PMID:	16118624

65.
Journal:	Int J Cancer. 2006 Feb 15;118(4):907-15.
Title:	DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.
Author:	Wynter, Coral V A\|Kambara, Takeshi\|Walsh, Michael D\|Leggett, Barbara A\|Young, Joanne\|Jass, Jeremy R
PMID:	16152625

66.
Journal:	Genome Res. 2006 Feb;16(2):282-9.
Title:	Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Author:	Cheng, Yu-Wei\|Shawber, Carrie\|Notterman, Dan\|Paty, Philip\|Barany, Francis
PMID:	16369045

67.
Journal:	J Invest Dermatol. 2006 Feb;126(2):422-31.
Title:	Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma.
Author:	Marini, Alessandra\|Mirmohammadsadegh, Alireza\|Nambiar, Sandeep\|Gustrau, Annett\|Ruzicka, Thomas\|Hengge, Ulrich R
PMID:	16374457

68.
Journal:	J Mol Diagn. 2006 Feb;8(1):68-75.
Title:	Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer.
Author:	Fox, Edward J\|Leahy, Dermot T\|Geraghty, Robert\|Mulcahy, Hugh E\|Fennelly, David\|Hyland, John M\|O'Donoghue, Diarmuid P\|Sheahan, Kieran
PMID:	16436636

69.
Journal:	Int J Cancer. 2006 Jul 15;119(2):264-8.
Title:	The prognostic impact of O6-Methylguanine-DNA Methyltransferase (MGMT) promotor hypermethylation in esophageal adenocarcinoma.
Author:	Baumann, S\|Keller, G\|Puhringer, F\|Napieralski, R\|Feith, M\|Langer, R\|Hofler, H\|Stein, H J\|Sarbia, M
PMID:	16477636

70.
Journal:	Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2101-8.
Title:	Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
Author:	Moreno, Victor\|Gemignani, Federica\|Landi, Stefano\|Gioia-Patricola, Lydie\|Chabrier, Amelie\|Blanco, Ignacio\|Gonzalez, Sara\|Guino, Elisabet\|Capella, Gabriel\|Canzian, Federico
PMID:	16609022

71.
Journal:	Cancer Causes Control. 2006 Jun;17(5):721-31.
Title:	O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States).
Author:	Tranah, Gregory J\|Bugni, James\|Giovannucci, Edward\|Ma, Jing\|Fuchs, Charles\|Hines, Lisa\|Samson, Leona\|Hunter, David J
PMID:	16633920

72.
Journal:	J Mol Diagn. 2006 May;8(2):193-201.
Title:	Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas.
Author:	Sugai, Tamotsu\|Habano, Wataru\|Jiao, Yu-Fei\|Tsukahara, Mitsunori\|Takeda, Yuichiro\|Otsuka, Koki\|Nakamura, Shin-ichi
PMID:	16645205

73.
Journal:	J Mol Diagn. 2006 May;8(2):209-17.
Title:	Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Brahmandam, Mohan\|Cantor, Mami\|Kirkner, Gregory J\|Spiegelman, Donna\|Makrigiorgos, G Mike\|Weisenberger, Daniel J\|Laird, Peter W\|Loda, Massimo\|Fuchs, Charles S
PMID:	16645207

74.
Journal:	Mod Pathol. 2006 Aug;19(8):1083-90.
Title:	Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Kawasaki, Takako\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	16699497

75.
Journal:	Genes Chromosomes Cancer. 2006 Aug;45(8):781-9.
Title:	CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer.
Author:	Kim, Young-Ho\|Petko, Zsolt\|Dzieciatkowski, Slavomir\|Lin, Li\|Ghiassi, Mahan\|Stain, Steve\|Chapman, William C\|Washington, Mary Kay\|Willis, Joseph\|Markowitz, Sanford D\|Grady, William M
PMID:	16708352

76.
Journal:	Genet Mol Res. 2006 Jun 30;5(2):315-22.
Title:	Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer.
Author:	Clarizia, Alessandra D\|Bastos-Rodrigues, Luciana\|Pena, Heloisa B\|Anacleto, Charles\|Rossi, Benedito\|Soares, Fernando A\|Lopes, Ademar\|Rocha, Jose Claudio C\|Caballero, Otavia\|Camargo, Anamaria\|Simpson, Andrew J G\|Pena, Sergio D J
PMID:	16819711

77.
Journal:	Oncol Rep. 2006 Aug;16(2):429-35.
Title:	Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas.
Author:	Ye, Chuanzhong\|Shrubsole, Martha J\|Cai, Qiuyin\|Ness, Reid\|Grady, William M\|Smalley, Walter\|Cai, Hui\|Washington, Kay\|Zheng, Wei
PMID:	16820927

78.
Journal:	Histopathology. 2006 Aug;49(2):121-31.
Title:	Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer.
Author:	Jass, J R\|Baker, K\|Zlobec, I\|Higuchi, T\|Barker, M\|Buchanan, D\|Young, J
PMID:	16879389

79.
Journal:	Anticancer Res. 2006 Jul-Aug;26(4B):2829-32.
Title:	Reduced expression level of mgmt mRNA and beta-catenin gene mutation in rat colon tumors.
Author:	Kinjo, Tatsuya\|Suzui, Masumi\|Morioka, Takamitsu\|Inamine, Morihiko\|Kaneshiro, Tatsuya\|Arakaki, Junya\|Chiba, Itaru\|Sunagawa, Nao\|Nishimaki, Tadashi\|Yoshimi, Naoki
PMID:	16886601

80.
Journal:	J Pathol. 2006 Nov;210(3):344-50.
Title:	Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas.
Author:	Judson, H\|Stewart, A\|Leslie, A\|Pratt, N R\|Baty, D U\|Steele, R J C\|Carey, F A
PMID:	16902913

81.
Journal:	Int J Cancer. 2006 Dec 1;119(11):2513-9.
Title:	Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis.
Author:	Ozaki, Kazuhide\|Nagasaka, Takeshi\|Notohara, Kenji\|Kambara, Takeshi\|Takeda, Masanori\|Sasamoto, Hiromi\|Jass, Jeremy R\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	16929496

82.
Journal:	Cancer Sci. 2006 Dec;97(12):1335-42.
Title:	Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions.
Author:	Ogawa, Taishi\|Yoshida, Tsutomu\|Tsuruta, Tomoko\|Saigenji, Katsunori\|Okayasu, Isao
PMID:	17032312

83.
Journal:	Ann N Y Acad Sci. 2006 Sep;1075:197-203.
Title:	Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients.
Author:	Taback, Bret\|Saha, Sukamal\|Hoon, Dave S B
PMID:	17108212

84.
Journal:	Am J Surg Pathol. 2006 Dec;30(12):1491-501.
Title:	Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points.
Author:	O'Brien, Michael J\|Yang, Shi\|Mack, Charline\|Xu, Huihong\|Huang, Christopher S\|Mulcahy, Elizabeth\|Amorosino, Mark\|Farraye, Francis A
PMID:	17122504

85.
Journal:	Verh Dtsch Ges Pathol. 2006;90:18-24.
Title:	Types of colorectal adenoma.
Author:	Lugli, A\|Jass, J R
PMID:	17867575

86.
Journal:	Carcinogenesis. 2007 Apr;28(4):769-76.
Title:	Microsatellite instability in aberrant crypt foci from patients without concurrent colon cancer.
Author:	Greenspan, Emily J\|Cyr, Jennifer L\|Pleau, Devon C\|Levine, Joel\|Rajan, Thiruchandurai V\|Rosenberg, Daniel W\|Heinen, Christopher D
PMID:	17088260

87.
Journal:	Histopathology. 2007 Jan;50(1):131-50.
Title:	Colorectal serrated adenocarcinoma.
Author:	Makinen, M J
PMID:	17204027

88.
Journal:	Int J Cancer. 2007 May 1;120(9):1922-9.
Title:	Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas.
Author:	Kaz, Andrew\|Kim, Young-Ho\|Dzieciatkowski, Slavomir\|Lynch, Henry\|Watson, Patrice\|Kay Washington, Mary\|Lin, Li\|Grady, William M
PMID:	17278092

89.
Journal:	Nucleic Acids Res. 2007;35(6):e41.
Title:	Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation.
Author:	Wojdacz, Tomasz K\|Dobrovic, Alexander
PMID:	17289753

90.
Journal:	Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title:	Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	17339237

91.
Journal:	World J Gastroenterol. 2007 Feb 14;13(6):950-4.
Title:	Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions.
Author:	Huang, Zhao-Hui\|Li, Li-Hua\|Yang, Fan\|Wang, Jin-Fu
PMID:	17352030

92.
Journal:	Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.
Title:	CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Kawasaki, Takako\|Clark, Jeffrey W\|Ryan, David P\|Kulke, Matthew H\|Enzinger, Peter C\|Wolpin, Brian M\|Loda, Massimo\|Fuchs, Charles S
PMID:	17372756

93.
Journal:	Am J Gastroenterol. 2007 May;102(5):1070-6. Epub 2007 Mar 22.
Title:	Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps.
Author:	Leung, Wai K\|To, Ka-Fai\|Man, Ellen P S\|Chan, Michael W Y\|Hui, Aric J\|Ng, Simon S M\|Lau, James Y W\|Sung, Joseph J Y
PMID:	17378912

94.
Journal:	Gastroenterology. 2007 Apr;132(4):1254-60. Epub 2007 Jan 25.
Title:	Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.
Author:	Konishi, Kazuo\|Shen, Lanlan\|Wang, Suna\|Meltzer, Stephen J\|Harpaz, Noam\|Issa, Jean-Pierre J
PMID:	17408633

95.
Journal:	World J Gastroenterol. 2007 Feb 28;13(8):1187-94.
Title:	Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic value.
Author:	Krtolica, Koviljka\|Krajnovic, Milena\|Usaj-Knezevic, Slavica\|Babic, Dragan\|Jovanovic, Dusan\|Dimitrijevic, Bogomir
PMID:	17451198

96.
Journal:	Orv Hetil. 2007 Apr 29;148(17):779-85.
Title:	[Stem cell theory of colorectal cancer and its connection with molecular-biological data].
Author:	Hagymasi, Krisztina\|Molnar, Bela\|Sipos, Ferenc\|Galamb, Orsolya\|Tulassay, Zsolt
PMID:	17452307

97.
Journal:	Oncol Rep. 2007 Jun;17(6):1461-7.
Title:	Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines.
Author:	Murakami, Jun\|Lee, You-Jin\|Kokeguchi, Susumu\|Tsujigiwa, Hidetsugu\|Asaumi, Jun-Ichi\|Nagatsuka, Hitoshi\|Fukui, Kazuhiro\|Kuroda, Masahiro\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	17487405

98.
Journal:	Int J Cancer. 2007 Nov 15;121(10):2293-300.
Title:	Tamoxifen accelerates proteasomal degradation of O6-methylguanine DNA methyltransferase in human cancer cells.
Author:	Kuo, Ching-Chuan\|Liu, Jin-Fen\|Shiah, Her-Shyong\|Ma, Li-Chen\|Chang, Jang-Yang
PMID:	17597106

99.
Journal:	Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title:	MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author:	Ogino, Shuji\|Hazra, Aditi\|Tranah, Gregory J\|Kirkner, Gregory J\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Hunter, David J\|Fuchs, Charles S
PMID:	17621591

100.
Journal:	Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6.
Title:	Promoter methylation status of multiple genes in uveal melanoma.
Author:	Merhavi, Efrat\|Cohen, Yoram\|Avraham, Bat Chen R\|Frenkel, Shahar\|Chowers, Itay\|Pe'er, Jacob\|Goldenberg-Cohen, Nitza
PMID:	17898258

101.
Journal:	Clin Cancer Res. 2007 Oct 1;13(19):5729-35.
Title:	Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.
Author:	Sanchez-de-Abajo, Ana\|de la Hoya, Miguel\|van Puijenbroek, Marjo\|Tosar, Alicia\|Lopez-Asenjo, J A\|Diaz-Rubio, Eduardo\|Morreau, Hans\|Caldes, Trinidad
PMID:	17908962

102.
Journal:	Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2363-72.
Title:	DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study.
Author:	Stern, Mariana C\|Conti, David V\|Siegmund, Kimberly D\|Corral, Roman\|Yuan, Jian-Min\|Koh, Woon-Puay\|Yu, Mimi C
PMID:	18006925

103.
Journal:	J Exp Clin Cancer Res. 2007 Dec;26(4):521-6.
Title:	Promoter hypermethylation of tumor-related genes in sporadic colorectal cancer in young patients.
Author:	Noda, H\|Mashima, R\|Kamiyama, H\|Okada, S\|Kawamura, Y J\|Konishi, F
PMID:	18365548

104.
Journal:	Clin Biochem. 2008 Jan;41(1-2):19-25. Epub 2007 Sep 25.
Title:	Detailed methylation patterns and protein expression profiles of MGMT in colorectal carcinoma surgical margins.
Author:	Zhang, Dingdong\|Bai, Yunfei\|Wang, Yan\|Luo, Junfeng\|Ge, Qinyu\|Qiao, Yingjuan\|Jia, Chao\|Lu, Zuhong
PMID:	18028895

105.
Journal:	Carcinogenesis. 2008 Feb;29(2):434-9.
Title:	Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Author:	Derks, Sarah\|Postma, Cindy\|Carvalho, Beatriz\|van den Bosch, Sandra M\|Moerkerk, Peter T M\|Herman, James G\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Meijer, Gerrit A\|van Engeland, Manon
PMID:	18048385

106.
Journal:	Eur J Cancer. 2008 Feb;44(3):400-7.
Title:	Combination of O6-methylguanine-DNA methyltransferase and thymidylate synthase for the prediction of fluoropyrimidine efficacy.
Author:	Nakajima, Takako Eguchi\|Yamada, Yasuhide\|Shimoda, Tadakazu\|Matsubara, Junichi\|Kato, Ken\|Hamaguchi, Tetsuya\|Shimada, Yasuhiro\|Okayama, Yoshihiro\|Oka, Toshinori\|Shirao, Kuniaki
PMID:	18068349

107.
Journal:	Mod Pathol. 2008 Mar;21(3):245-55.
Title:	CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Author:	Kawasaki, Takako\|Ohnishi, Mutsuko\|Nosho, Katsuhiko\|Suemoto, Yuko\|Kirkner, Gregory J\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18204436

108.
Journal:	BMC Genomics. 2008 Jan 31;9:59.
Title:	A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray.
Author:	Zhang, Dingdong\|Wang, Yan\|Bai, Yunfei\|Ge, Qinyu\|Qiao, Yingjuan\|Luo, Junfeng\|Jia, Chao\|Lu, Zuhong
PMID:	18237388

109.
Journal:	Int J Cancer. 2008 Jun 1;122(11):2429-36.
Title:	Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.
Author:	Nagasaka, Takeshi\|Goel, Ajay\|Notohara, Kenji\|Takahata, Takaomi\|Sasamoto, Hiromi\|Uchida, Takuyuki\|Nishida, Naoshi\|Tanaka, Noriaki\|Boland, Clement Richard\|Matsubara, Nagahide
PMID:	18240147

110.
Journal:	Cancer Epidemiol Biomarkers Prev. 2008 Feb;17(2):311-9.
Title:	Large-scale evaluation of genetic variants in candidate genes for colorectal cancer risk in the Nurses' Health Study and the Health Professionals' Follow-up Study.
Author:	Hazra, Aditi\|Chanock, Stephen\|Giovannucci, Edward\|Cox, David G\|Niu, Tianhua\|Fuchs, Charles\|Willett, Walter C\|Hunter, David J
PMID:	18268114

111.
Journal:	Cancer Sci. 2008 Feb;99(2):253-9.
Title:	Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy.
Author:	Saito, Kana\|Sakurai, Shinji\|Sano, Takaaki\|Sakamoto, Kazuha\|Asao, Takayuki\|Hosoya, Yoshinori\|Nakajima, Takashi\|Kuwano, Hiroyuki
PMID:	18271923

112.
Journal:	J Korean Med Sci. 2008 Apr;23(2):270-7.
Title:	CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria.
Author:	Kim, Hee Cheol\|Lee, Hyeon Jung\|Roh, Seon Ae\|Kim, Jung-Sun\|Yu, Chang Sik\|Kim, Jin Cheon
PMID:	18437011

113.
Journal:	Clin Cancer Res. 2008 May 1;14(9):2560-9.
Title:	Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Author:	Suehiro, Yutaka\|Wong, Chi Wai\|Chirieac, Lucian R\|Kondo, Yutaka\|Shen, Lanlan\|Webb, C Renee\|Chan, Yee Wai\|Chan, Annie S Y\|Chan, Tsun Leung\|Wu, Tsung-Teh\|Rashid, Asif\|Hamanaka, Yuichiro\|Hinoda, Yuji\|Shannon, Rhonda L\|Wang, Xuemei\|Morris, Jeffrey\|Issa, Jean-P
PMID:	18451217

114.
Journal:	Eur J Cancer. 2008 Jun;44(9):1290-301.
Title:	Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.
Author:	Deng, Guoren\|Kakar, Sanjay\|Tanaka, Hirofumi\|Matsuzaki, Koji\|Miura, Soichiro\|Sleisenger, Marvin H\|Kim, Young S
PMID:	18486467

115.
Journal:	J Clin Oncol. 2008 Jun 1;26(16):2690-8.
Title:	Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
Author:	Braun, Michael S\|Richman, Susan D\|Quirke, Philip\|Daly, Catherine\|Adlard, Julian W\|Elliott, Faye\|Barrett, Jennifer H\|Selby, Peter\|Meade, Angela M\|Stephens, Richard J\|Parmar, Mahesh K B\|Seymour, Matthew T
PMID:	18509181

116.
Journal:	Neoplasia. 2008 Jun;10(6):534-41.
Title:	PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author:	Nosho, Katsuhiko\|Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Zepf, Dimity\|Yan, Liying\|Longtine, Janina A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18516290

117.
Journal:	Int J Cancer. 2008 Dec 1;123(11):2587-93.
Title:	Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
Author:	Kim, Yong Ho\|Kakar, Sanjay\|Cun, Lisa\|Deng, Guoren\|Kim, Young S
PMID:	18798261

118.
Journal:	Med Sci Monit. 2008 Oct;14(10):BR219-25.
Title:	Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.
Author:	Krakowczyk, Lukasz\|Strzelczyk, Joanna K\|Adamek, Brygida\|Zalewska-Ziob, Marzena\|Arendt, Jerzy\|Poltorak, Stanislaw\|Maciejewski, Boguslaw\|Wiczkowski, Andrzej
PMID:	18830187

119.
Journal:	Eur J Cancer. 2008 Nov;44(17):2689-95.
Title:	Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions.
Author:	Ramirez, N\|Bandres, E\|Navarro, A\|Pons, A\|Jansa, S\|Moreno, I\|Martinez-Rodenas, F\|Zarate, R\|Bitarte, N\|Monzo, M\|Garcia-Foncillas, J
PMID:	18938072

120.
Journal:	PLoS One. 2008;3(11):e3698.
Title:	Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author:	Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Kure, Shoko\|Kirkner, Gregory J\|Schernhammer, Eva S\|Hazra, Aditi\|Hunter, David J\|Quackenbush, John\|Spiegelman, Donna\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19002263

121.
Journal:	Mol Cancer. 2008 Dec 31;7:94.
Title:	Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author:	Ahlquist, Terje\|Lind, Guro E\|Costa, Vera L\|Meling, Gunn I\|Vatn, Morten\|Hoff, Geir S\|Rognum, Torleiv O\|Skotheim, Rolf I\|Thiis-Evensen, Espen\|Lothe, Ragnhild A
PMID:	19117505

122.
Journal:	Gut. 2009 Jan;58(1):90-6.
Title:	CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	18832519

123.
Journal:	Gynecol Oncol. 2009 Jan;112(1):224-8.
Title:	Absence of MGMT promoter methylation in endometrial cancer.
Author:	Rimel, B J\|Huettner, Phyllis\|Powell, Matthew A\|Mutch, David G\|Goodfellow, Paul J
PMID:	18973931

124.
Journal:	Oncogene. 2009 Feb 5;28(5):734-41.
Title:	Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.
Author:	Bugni, J M\|Meira, L B\|Samson, L D
PMID:	19029948

125.
Journal:	Oncogene. 2009 Feb 12;28(6):899-909.
Title:	Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters.
Author:	Menigatti, M\|Truninger, K\|Gebbers, J-O\|Marbet, U\|Marra, G\|Schar, P
PMID:	19060925

126.
Journal:	Neoplasia. 2009 Jan;11(1):87-95.
Title:	JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Kure, Shoko\|Irahara, Natsumi\|Baba, Yoshifumi\|Chen, Li\|Kirkner, Gregory J\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19107235

127.
Journal:	Environ Mol Mutagen. 2009 Mar;50(2):127-33.
Title:	NAT2 fast acetylator genotype and MGMT promoter methylation may contribute to gender difference in K-RAS mutation occurrence in Taiwanese colorectal cancer.
Author:	Huang, Chi-Chou\|Chien, Wen-Pin\|Wong, Ruey-Hong\|Cheng, Ya-Wen\|Chen, Meng-Cheng\|Lee, Huei
PMID:	19107910

128.
Journal:	Carcinogenesis. 2009 Mar;30(3):494-9.
Title:	Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B.
Author:	Asaka, Shin-ichi\|Arai, Yoshiko\|Nishimura, Yoji\|Yamaguchi, Kensei\|Ishikubo, Tsutomu\|Yatsuoka, Toshimasa\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	19147861

129.
Journal:	Ann Oncol. 2009 Jul;20(7):1216-22.
Title:	MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
Author:	de Vogel, S\|Weijenberg, M P\|Herman, J G\|Wouters, K A D\|de Goeij, A F P M\|van den Brandt, P A\|de Bruine, A P\|van Engeland, M
PMID:	19164452

130.
Journal:	J Mol Diagn. 2009 Mar;11(2):102-8.
Title:	High quality assessment of DNA methylation in archival tissues from colorectal cancer patients using quantitative high-resolution melting analysis.
Author:	Balic, Marija\|Pichler, Martin\|Strutz, Jasmin\|Heitzer, Ellen\|Ausch, Christoph\|Samonigg, Hellmut\|Cote, Richard J\|Dandachi, Nadia
PMID:	19179456

131.
Journal:	Cancer Sci. 2009 Jun;100(6):1005-11.
Title:	Methylation of estrogen receptor 1 in colorectal adenomas is not age-dependent, but is correlated with K-ras mutation.
Author:	Horii, Joichiro\|Hiraoka, Sakiko\|Kato, Jun\|Saito, Shunsuke\|Harada, Keita\|Fujita, Hideyuki\|Kaji, Eisuke\|Yamamoto, Kazuhide
PMID:	19302287

132.
Journal:	Genet Test Mol Biomarkers. 2009 Feb;13(1):67-71.
Title:	The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients.
Author:	Chen, Shee-Ping\|Chiu, Sheng-Chun\|Wu, Chang-Chieh\|Lin, Shinn-Zong\|Kang, Jung-Cheng\|Chen, Yi-Lin\|Lin, Po-Cheng\|Pang, Cheng-Yoong\|Harn, Horng-Jyh
PMID:	19309276

133.
Journal:	J Surg Oncol. 2009 Jul 1;100(1):69-74.
Title:	Promoter hypermethylation of tumor-related genes in peritoneal lavage and the prognosis of patients with colorectal cancer.
Author:	Kamiyama, Hidenori\|Noda, Hiroshi\|Takata, Osamu\|Suzuki, Koichi\|Kawamura, Yutaka\|Konishi, Fumio
PMID:	19384904

134.
Journal:	Mod Pathol. 2009 Jul;22(7):922-32.
Title:	SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Firestein, Ron\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19430421

135.
Journal:	Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title:	DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Baba, Yoshifumi\|Kirkner, Gregory J\|Chen, Li\|Gokhale, Sumita\|Hazra, Aditi\|Spiegelman, Donna\|Giovannucci, Edward L\|Jaenisch, Rudolf\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19470733

136.
Journal:	Adv Anat Pathol. 2009 Mar;16(2):79-91.
Title:	Pathologic features and biologic importance of colorectal serrated polyps.
Author:	Vakiani, Efsevia\|Yantiss, Rhonda K
PMID:	19550369

137.
Journal:	Dis Colon Rectum. 2009 Aug;52(8):1452-9; discussion 1459-63.
Title:	Stool methylation-specific polymerase chain reaction assay for the detection of colorectal neoplasia in Korean patients.
Author:	Baek, Yoo Hum\|Chang, Eugene\|Kim, Young Jin\|Kim, Bo Kyoung\|Sohn, Jin Hee\|Park, Dong Il
PMID:	19617759

138.
Journal:	Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title:	A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author:	Nosho, Katsuhiko\|Kure, Shoko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Spiegelman, Donna\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19686742

139.
Journal:	Mod Pathol. 2009 Dec;22(12):1588-99.
Title:	MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.
Author:	Hawkins, Nicholas J\|Lee, James H-F\|Wong, Justin J-L\|Kwok, Chau-To\|Ward, Robyn L\|Hitchins, Megan P
PMID:	19734844

140.
Journal:	Cancer Prev Res (Phila). 2009 Sep;2(9):814-22.
Title:	Concordant DNA methylation in synchronous colorectal carcinomas.
Author:	Konishi, Kazuo\|Shen, Lanlan\|Jelinek, Jaroslav\|Watanabe, Yoshiyuki\|Ahmed, Saira\|Kaneko, Kazuhiro\|Kogo, Mari\|Takano, Toshihumi\|Imawari, Michio\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	19737982

141.
Journal:	J Int Med Res. 2009 Jul-Aug;37(4):1038-45.
Title:	Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
Author:	Kominami, K\|Nagasaka, T\|Cullings, H M\|Hoshizima, N\|Sasamoto, H\|Young, J\|Leggett, B A\|Tanaka, N\|Matsubara, N
PMID:	19761686

142.
Journal:	Clin Cancer Res. 2009 Oct 1;15(19):6185-91.
Title:	Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer.
Author:	Lee, Bo Bin\|Lee, Eun Ju\|Jung, Eun Hyun\|Chun, Ho-Kyung\|Chang, Dong Kyoung\|Song, Sang Yong\|Park, Joobae\|Kim, Duk-Hwan
PMID:	19773381

143.
Journal:	Cancer Prev Res (Phila). 2009 Oct;2(10):862-7.
Title:	Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.
Author:	Candiloro, Ida L M\|Dobrovic, Alexander
PMID:	19789298

144.
Journal:	Anticancer Res. 2009 Dec;29(12):5053-5.
Title:	Methylation of the MGMT gene is frequently detected in advanced gastric carcinoma.
Author:	Hibi, Kenji\|Sakata, Makiko\|Yokomizo, Kazuaki\|Kitamura, Yo-Hei\|Sakuraba, Kazuma\|Shirahata, Atsushi\|Goto, Tetsuhiro\|Mizukami, Hiroki\|Saito, Mitsuo\|Ishibashi, Kazuyoshi\|Kigawa, Gaku\|Nemoto, Hiroshi\|Sanada, Yutaka
PMID:	20044616

145.
Journal:	Asian Pac J Cancer Prev. 2009;10(6):1183-8.
Title:	Effects of amino acid substitution polymorphisms of two DNA methyltransferases on susceptibility to sporadic colorectal cancer.
Author:	Khatami, Fatemeh\|Noorinayer, Babak\|Mohebi, Seyed Reza\|Ghiasi, Somayeh\|Mohebi, Reza\|Hashemi, Mohhamad\|Zali, Mohammad Reza
PMID:	20192566

146.
Journal:	Hepatogastroenterology. 2009 Nov-Dec;56(96):1642-4.
Title:	MGMT gene is aberrantly methylated from the early stages of colorectal cancers.
Author:	Hibi, Kenji\|Goto, Tetsuhiro\|Mizukami, Hiroki\|Kitamura, Youhei\|Sakata, Makiko\|Saito, Mitsuo\|Ishibashi, Kazuyoshi\|Kigawa, Gaku\|Nemoto, Hiroshi\|Sanada, Yutaka
PMID:	20214209

147.
Journal:	Neuropathology. 2010 Jun;30(3):273-8.
Title:	Intramedullary solitary fibrous tumor of dorsal spinal cord.
Author:	Ciappetta, Pasqualino\|D'Urso, Pietro Ivo\|Cimmino, Antonia\|Ingravallo, Giuseppe\|Rossi, Roberta\|Colamaria, Antonio\|D'Urso, Oscar Fernando
PMID:	19751244

148.
Journal:	Mol Carcinog. 2010 Jan;49(1):94-103.
Title:	Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model.
Author:	Borinstein, Scott C\|Conerly, Melissa\|Dzieciatkowski, Slavomir\|Biswas, Swati\|Washington, M Kay\|Trobridge, Patty\|Henikoff, Steve\|Grady, William M
PMID:	19777566

149.
Journal:	Mutagenesis. 2010 Jan;25(1):83-95.
Title:	Effects of O6-methylguanine-DNA methyltransferase (MGMT) polymorphisms on cancer: a meta-analysis.
Author:	Zhong, Yu\|Huang, Yongsheng\|Huang, Yan\|Zhang, Tianbao\|Ma, Chengying\|Zhang, Shuyong\|Fan, Weiwei\|Chen, Hongyan\|Qian, Ji\|Lu, Daru
PMID:	19892775

150.
Journal:	Oncol Rep. 2010 Jan;23(1):191-7.
Title:	CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients.
Author:	Hiraki, Masatsugu\|Kitajima, Yoshihiko\|Nakafusa, Yuji\|Nakamura, Jun\|Hashiguchi, Kazuyoshi\|Sumi, Kenji\|Noshiro, Hirokazu\|Miyazaki, Kohji
PMID:	19956881

151.
Journal:	Cancer Chemother Pharmacol. 2010 Oct;66(5):829-35.
Title:	A phase I trial of lomeguatrib and irinotecan in metastatic colorectal cancer.
Author:	Sabharwal, A\|Corrie, P G\|Midgley, R S\|Palmer, C\|Brady, J\|Mortimer, P\|Watson, A J\|Margison, G P\|Middleton, M R
PMID:	20039040

152.
Journal:	Cancer Prev Res (Phila). 2010 Jan;3(1):92-100.
Title:	Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation.
Author:	Duthie, Susan J\|Grant, George\|Pirie, Lynn P\|Watson, Amanda J\|Margison, Geoffrey P
PMID:	20051376

153.
Journal:	Clin Cancer Res. 2010 Jan 15;16(2):743-9.
Title:	Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib.
Author:	Watson, Amanda J\|Sabharwal, Ami\|Thorncroft, Mary\|McGown, Gail\|Kerr, Richard\|Bojanic, Stana\|Soonawalla, Zahir\|King, Alexandra\|Miller, Andrea\|Waller, Sue\|Leung, Hing\|Margison, Geoffrey P\|Middleton, Mark R
PMID:	20068091

154.
Journal:	Ann Surg Oncol. 2010 Jul;17(7):1767-76.
Title:	Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas.
Author:	Kim, Jin C\|Choi, Jin S\|Roh, Seon A\|Cho, Dong H\|Kim, Tae W\|Kim, Yong S
PMID:	20077021

155.
Journal:	J Cancer Res Clin Oncol. 2010 Aug;136(8):1135-42.
Title:	MGMT -535G>T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy.
Author:	Park, Jee Hyun\|Kim, Nung Soo\|Park, Jae Yong\|Chae, Yee Soo\|Kim, Jong Gwang\|Sohn, Sang Kyun\|Moon, Joon Ho\|Kang, Byung Woog\|Ryoo, Hun Mo\|Bae, Sung Hwa\|Choi, Gyu Seog\|Jun, Soo-Han
PMID:	20091185

156.
Journal:	DNA Repair (Amst). 2010 Apr 4;9(4):421-8.
Title:	MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.
Author:	Loh, Yet Hua\|Mitrou, Panagiota N\|Bowman, Richard\|Wood, Angela\|Jeffery, Hannah\|Luben, Robert N\|Lentjes, Marleen A H\|Khaw, Kay-Tee\|Rodwell, Sheila A
PMID:	20096652

157.
Journal:	PLoS One. 2010 Jan 19;5(1):e8777.
Title:	Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.
Author:	Gonzalo, Victoria\|Lozano, Juan Jose\|Munoz, Jenifer\|Balaguer, Francesc\|Pellise, Maria\|Rodriguez de Miguel, Cristina\|Andreu, Montserrat\|Jover, Rodrigo\|Llor, Xavier\|Giraldez, M Dolores\|Ocana, Teresa\|Serradesanferm, Anna\|Alonso-Espinaco, Virginia\|Jimeno, Mire
PMID:	20098741

158.
Journal:	Cancer. 2010 Oct 1;116(19):4495-501.
Title:	Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas.
Author:	Paun, Bogdan C\|Kukuruga, Debra\|Jin, Zhe\|Mori, Yuriko\|Cheng, Yulan\|Duncan, Mark\|Stass, Sanford A\|Montgomery, Elizabeth\|Hutcheon, David\|Meltzer, Stephen J
PMID:	20572039

159.
Journal:	Clin Colorectal Cancer. 2010 Jul;9(3):168-76.
Title:	Novel methylation panel for the early detection of colorectal tumors in stool DNA.
Author:	Azuara, Daniel\|Rodriguez-Moranta, Francisco\|de Oca, Javier\|Soriano-Izquierdo, Antonio\|Mora, Josefina\|Guardiola, Jordi\|Biondo, Sebastiano\|Blanco, Ignacio\|Peinado, Miguel Angel\|Moreno, Victor\|Esteller, Manel\|Capella, Gabriel
PMID:	20643622

160.
Journal:	World J Gastroenterol. 2010 Jul 28;16(28):3553-60.
Title:	Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas.
Author:	Psofaki, Vasiliki\|Kalogera, Chryssoula\|Tzambouras, Nikolaos\|Stephanou, Dimitrios\|Tsianos, Epameinondas\|Seferiadis, Konstantin\|Kolios, Georgios
PMID:	20653064

161.
Journal:	Cancer Genet Cytogenet. 2010 Sep;201(2):128-32.
Title:	Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
Author:	Pehlivan, Sacide\|Artac, Mehmet\|Sever, Tugce\|Bozcuk, Hakan\|Kilincarslan, Can\|Pehlivan, Mustafa
PMID:	20682398

162.
Journal:	Carcinogenesis. 2010 Dec;31(12):2111-7.
Title:	Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.
Author:	Wirtz, Stefan\|Nagel, Georg\|Eshkind, Leonid\|Neurath, Markus F\|Samson, Leona D\|Kaina, Bernd
PMID:	20732909

163.
Journal:	Med Sci Monit. 2010 Oct;16(10):CR469-74.
Title:	Effects of X-ray irradiation on methylation levels of p16, MGMT and APC genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.
Author:	Krakowczyk, Lukasz\|Blamek, Slawomir\|Strzelczyk, Joanna Katarzyna\|Plachetka, Anna\|Maciejewski, Adam\|Poltorak, Stanislaw\|Wiczkowski, Andrzej
PMID:	20885350

164.
Journal:	Adv Genet. 2010;70:309-23.
Title:	Epigenetic drivers of genetic alterations.
Author:	Toyota, Minoru\|Suzuki, Hiromu
PMID:	20920753

165.
Journal:	Gut. 2010 Nov;59(11):1516-26.
Title:	Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers.
Author:	Svrcek, Magali\|Buhard, Olivier\|Colas, Chrystelle\|Coulet, Florence\|Dumont, Sylvie\|Massaoudi, Illiasse\|Lamri, Amel\|Hamelin, Richard\|Cosnes, Jacques\|Oliveira, Carla\|Seruca, Raquel\|Gaub, Marie-Pierre\|Legrain, Michele\|Collura, Ada\|Lascols, Olivier\|Tiret, Emman
PMID:	20947886

166.
Journal:	Cancer Prev Res (Phila). 2010 Nov;3(11):1409-16.
Title:	An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy.
Author:	Xie, Jenny\|Guillemette, Shawna\|Peng, Min\|Gilbert, Candace\|Buermeyer, Andrew\|Cantor, Sharon B
PMID:	20978114

167.
Journal:	Am J Pathol. 2010 Dec;177(6):2731-40.
Title:	Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author:	Tanaka, Noriko\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Shima, Kaori\|Quackenbush, John\|Haigis, Kevin M\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21037082

168.
Journal:	Mod Pathol. 2011 Jan;24(1):126-37.
Title:	Hierarchical clustering analysis of pathologic and molecular data identifies prognostically and biologically distinct groups of colorectal carcinomas.
Author:	Furlan, Daniela\|Carnevali, Ileana W\|Bernasconi, Barbara\|Sahnane, Nora\|Milani, Katia\|Cerutti, Roberta\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Bertoni, Francesco\|Kwee, Ivo\|Pastorino, Roberta\|Carlo, Capella
PMID:	20852594

169.
Journal:	Cancer Epidemiol. 2011 Aug;35(4):369-74.
Title:	SMAD7 and MGMT genotype variants and cancer incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.
Author:	Loh, Yet Hua\|Mitrou, Panagiota N\|Wood, Angela\|Luben, Robert N\|McTaggart, Alison\|Khaw, Kay-Tee\|Rodwell, Sheila A
PMID:	21075068

170.
Journal:	Oncol Rep. 2011 Jan;25(1):253-8.
Title:	Tissue sampling for mutation analysis in colorectal cancer: K-ras is homogeneously distributed throughout the tumor tissue.
Author:	Ekelund, Susanne\|Papadogiannakis, Nikos\|Olivecrona, Hans\|Lindforss, Ulrik
PMID:	21109984

171.
Journal:	Cancer Causes Control. 2011 Feb;22(2):301-9.
Title:	MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Suzuki, Maiko\|Yamauchi, Mai\|Hayashi, Marika\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21140203

172.
Journal:	Hum Pathol. 2011 Feb;42(2):244-53.
Title:	Histologic characteristics of non-microsatellite-instable colon adenomas correlate with distinct molecular patterns.
Author:	Neuville, Agnes\|Nicolet, Celine\|Meyer, Nicolas\|Schneider, Anne\|Legrain, Michele\|Brigand, Cecile\|Duclos, Bernard\|Bachellier, Philippe\|Oudet, Pierre\|Bellocq, Jean-Pierre\|Kedinger, Michele\|Gaub, Marie-Pierre\|Guenot, Dominique
PMID:	21238786

173.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Jan;14(1):52-6.
Title:	[Gene methylation in stool for the screening of colorectal cancer and pre-malignant lesions].
Author:	Kang, Yan-Ping\|Cao, Fu-Ao\|Chang, Wen-Jun\|Lou, Zheng\|Wang, Hao\|Wu, Ling-Ling\|Fu, Chuan-Gang\|Cao, Guang-Wen
PMID:	21271382

174.
Journal:	Tumour Biol. 2011 Oct;32(5):845-52.
Title:	Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors.
Author:	Abouzeid, Hamdy E\|Kassem, Abdel Meguid\|Abdel Wahab, Abdel Hady\|El-mezayen, Hatem A\|Sharad, Hayaat\|Abdel Rahman, Shaimaa
PMID:	21274674

175.
Journal:	Hum Pathol. 2011 Jul;42(7):1047-52.
Title:	A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author:	Pancione, Massimo\|Di Blasi, Arturo\|Sabatino, Lina\|Fucci, Alessandra\|Dalena, Anna Maria\|Palombi, Natalia\|Carotenuto, Pietro\|Aquino, Gabriella\|Daniele, Bruno\|Normanno, Nicola\|Colantuoni, Vittorio
PMID:	21315413

176.
Journal:	Radiat Res. 2011 May;175(5):575-87.
Title:	The effect of radiation quality on genomic DNA methylation profiles in irradiated human cell lines.
Author:	Goetz, Wilfried\|Morgan, Michelle N M\|Baulch, Janet E
PMID:	21375360

177.
Journal:	Am J Pathol. 2011 Apr;178(4):1835-46.
Title:	Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis.
Author:	Ju, Hai-Xing\|An, Byonggu\|Okamoto, Yasuyuki\|Shinjo, Keiko\|Kanemitsu, Yukihide\|Komori, Koji\|Hirai, Takashi\|Shimizu, Yasuhiro\|Sano, Tsuyoshi\|Sawaki, Akira\|Tajika, Masahiro\|Yamao, Kenji\|Fujii, Makiko\|Murakami, Hideki\|Osada, Hirotaka\|Ito, Hidemi\|Takeuchi, Ichi
PMID:	21406167

178.
Journal:	Mod Pathol. 2011 Sep;24(9):1221-8.
Title:	Folate receptor-alpha expression in resectable hepatic colorectal cancer metastases: patterns and significance.
Author:	D'Angelica, Michael\|Ammori, John\|Gonen, Mithat\|Klimstra, David S\|Low, Philip S\|Murphy, Linda\|Weiser, Martin R\|Paty, Philip B\|Fong, Yuman\|Dematteo, Ronald P\|Allen, Peter\|Jarnagin, William R\|Shia, Jinru
PMID:	21572402

179.
Journal:	J Pathol. 2011 Nov;225(3):336-43.
Title:	Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.
Author:	Zlobec, Inti\|Bihl, Michel\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	21660972

180.
Journal:	Int J Oncol. 2011 Sep;39(3):683-8.
Title:	Hypermethylation of promoter regions of the APC1A and p16INK4a genes in relation to prognosis and tumor characteristics in cervical cancer patients.
Author:	Lof-Ohlin, Zarah M\|Sorbe, Bengt\|Wingren, Sten\|Nilsson, Torbjorn K
PMID:	21674126

181.
Journal:	Langenbecks Arch Surg. 2011 Oct;396(7):1017-26.
Title:	Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence.
Author:	Lee, Kyung-Hwa\|Lee, Ji-Shin\|Nam, Jong-Hee\|Choi, Chan\|Lee, Min-Cheol\|Park, Chang-Soo\|Juhng, Sang-Woo\|Lee, Jae-Hyuk
PMID:	21706233

182.
Journal:	Oncology. 2011;80(3-4):195-207.
Title:	Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair.
Author:	Zhang, Jihong\|Stevens, Malcolm F G\|Hummersone, Marc\|Madhusudan, Srinivasan\|Laughton, Charles A\|Bradshaw, Tracey D
PMID:	21720182

183.
Journal:	PLoS One. 2011;6(6):e21102.
Title:	B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author:	Schernhammer, Eva S\|Giovannucci, Edward\|Baba, Yoshifumi\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21738611

184.
Journal:	BMC Cancer. 2011 Aug 10;11:344.
Title:	The CpG island methylator phenotype may confer a survival benefit in patients with stage II or III colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy.
Author:	Min, Byung-Hoon\|Bae, Jeong Mo\|Lee, Eui Jin\|Yu, Hong Suk\|Kim, Young-Ho\|Chang, Dong Kyung\|Kim, Hee Cheol\|Park, Cheol Keun\|Lee, Suk-Hee\|Kim, Kyoung-Mee\|Kang, Gyeong Hoon
PMID:	21827707

185.
Journal:	Fam Cancer. 2011 Dec;10(4):623-31.
Title:	Familial colorectal cancer type X syndrome: two distinct molecular entities?
Author:	Francisco, Ines\|Albuquerque, Cristina\|Lage, Pedro\|Belo, Helio\|Vitoriano, Ines\|Filipe, Bruno\|Claro, Isabel\|Ferreira, Sara\|Rodrigues, Paula\|Chaves, Paula\|Leitao, Carlos Nobre\|Pereira, Antonio Dias
PMID:	21837511

186.
Journal:	PLoS One. 2011;6(11):e27889.
Title:	DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.
Author:	Konishi, Kazuo\|Watanabe, Yoshiyuki\|Shen, Lanlan\|Guo, Yi\|Castoro, Ryan J\|Kondo, Kimie\|Chung, Woonbok\|Ahmed, Saira\|Jelinek, Jaroslav\|Boumber, Yanis A\|Estecio, Marcos R\|Maegawa, Shinji\|Kondo, Yutaka\|Itoh, Fumio\|Imawari, Michio\|Hamilton, Stanley R\|Issa, Jean-
PMID:	22132162

187.
Journal:	Balkan J Med Genet. 2011 Dec;14(2):25-34.
Title:	Alterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancer.
Author:	Onrat, St\|Ceken, I\|Ellidokuz, E\|Kupelioglu, A
PMID:	24052709

188.
Journal:	Int J Cancer. 2012 Apr 1;130(7):1567-76.
Title:	p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers.
Author:	Bond, Catherine E\|Umapathy, Aarti\|Ramsnes, Ingunn\|Greco, Sonia A\|Zhen Zhao, Zhen\|Mallitt, Kylie-Ann\|Buttenshaw, Ron L\|Montgomery, Grant W\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	21557216

189.
Journal:	Int J Cancer. 2012 Aug 15;131(4):813-20.
Title:	Oncogenic PIK3CA mutations in colorectal cancers and polyps.
Author:	Whitehall, Vicki L J\|Rickman, Celestine\|Bond, Catherine E\|Ramsnes, Ingunn\|Greco, Sonia A\|Umapathy, Aarti\|McKeone, Diane\|Faleiro, Rebecca J\|Buttenshaw, Ron L\|Worthley, Daniel L\|Nayler, Sam\|Zhao, Zhen Zhen\|Montgomery, Grant W\|Mallitt, Kylie-Ann\|Jass, Jeremy
PMID:	21932420

190.
Journal:	BMC Cancer. 2012 Jan 13;12:12.
Title:	Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method.
Author:	Tournier, Benjamin\|Chapusot, Caroline\|Courcet, Emilie\|Martin, Laurent\|Lepage, Come\|Faivre, Jean\|Piard, Francoise
PMID:	22243995

191.
Journal:	Int J Cancer. 2012 Oct 15;131(8):1790-9.
Title:	Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.
Author:	Garcia-Solano, J\|Conesa-Zamora, P\|Carbonell, P\|Trujillo-Santos, J\|Torres-Moreno D, D\|Pagan-Gomez, I\|Rodriguez-Braun, E\|Perez-Guillermo, M
PMID:	22287190

192.
Journal:	Methods Mol Biol. 2012;863:3-14.
Title:	Epigenetic markers of early tumor development.
Author:	Dumitrescu, Ramona G
PMID:	22359284

193.
Journal:	Rev Col Bras Cir. 2012;39(1):48-53.
Title:	Evaluation of the expression of the MGMT gene in normal and neoplastic tissue of patients with colorectal cancer.
Author:	Cordeiro, Adriana Teixeira\|Silva, Camila Morais Goncalves da\|Bartchewsky Junior, Waldemar\|Ribeiro, Marcelo Lima\|Martinez, Carlos Augusto Real
PMID:	22481706

194.
Journal:	Front Oncol. 2012 Feb 27;2:7.
Title:	Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Terracciano, Luigi\|Lugli, Alessandro
PMID:	22655257

195.
Journal:	Histopathology. 2012 Nov;61(5):777-87.
Title:	The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	22803799

196.
Journal:	Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2069-75.
Title:	Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer.
Author:	Dallol, Ashraf\|Al-Maghrabi, Jaudah\|Buhmeida, Abdelbaset\|Gari, Mamdooh A\|Chaudhary, Adeel G\|Schulten, Hans-Juergen\|Abuzenadah, Adel M\|Al-Ahwal, Mahmoud S\|Sibiany, Abdulrahman\|Al-Qahtani, Mohammed H
PMID:	23010642

197.
Journal:	Clin Cancer Res. 2012 Nov 15;18(22):6136-46.
Title:	Expression profiling of archival tumors for long-term health studies.
Author:	Waldron, Levi\|Ogino, Shuji\|Hoshida, Yujin\|Shima, Kaori\|McCart Reed, Amy E\|Simpson, Peter T\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Segata, Nicola\|Vargas, Ana Cristina\|Cummings, Margaret C\|Lakhani, Sunil R\|Kirkner, Gregory J\|Giovannucci, Edward\|Quackenbush, John\|
PMID:	23136189

198.
Journal:	Rep Pract Oncol Radiother. 2012 Jan 23;17(1):13-8.
Title:	Analysis of O6-methylguanine-DNA methyltransferase methylation status in sporadic colon polyps.
Author:	Kycler, Witold\|Szarzynska, Bronislawa\|Lozinski, Cezary\|Korski, Konstanty\|Lamperska, Katarzyna
PMID:	24376999

199.
Journal:	Int J Cancer. 2013 Apr 15;132(8):1800-10.
Title:	Molecular patterns in the evolution of serrated lesion of the colorectum.
Author:	Gaiser, Timo\|Meinhardt, Sandra\|Hirsch, Daniela\|Killian, Jonathan Keith\|Gaedcke, Jochen\|Jo, Peter\|Ponsa, Immaculada\|Miro, Rosa\|Ruschoff, Josef\|Seitz, Gerhard\|Hu, Yue\|Camps, Jordi\|Ried, Thomas
PMID:	23011871

200.
Journal:	Int J Oncol. 2013 Jan;42(1):127-33.
Title:	DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients.
Author:	Nilsson, Torbjorn K\|Lof-Ohlin, Zarah M\|Sun, Xiao-Feng
PMID:	23128528

201.
Journal:	Mol Biol Rep. 2013 May;40(5):3851-7.
Title:	Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.
Author:	Mokarram, P\|Zamani, M\|Kavousipour, S\|Naghibalhossaini, F\|Irajie, C\|Moradi Sarabi, M\|Hosseini, S V
PMID:	23271133

202.
Journal:	Cancer. 2013 May 1;119(9):1752-60.
Title:	Cohypermethylation of p14 in combination with CADM1 or DCC as a recurrence-related prognostic indicator in stage I esophageal squamous cell carcinoma.
Author:	Lee, Eunju\|Lee, Bo Bin\|Ko, Eunkyung\|Kim, Yujin\|Han, Jungho\|Shim, Young Mog\|Park, Joobae\|Kim, Duk-Hwan
PMID:	23310950

203.
Journal:	Epigenetics. 2013 Feb;8(2):157-63.
Title:	Human metastable epiallele candidates link to common disorders.
Author:	Harris, R Alan\|Nagy-Szakal, Dorottya\|Kellermayer, Richard
PMID:	23321599

204.
Journal:	Clin Colorectal Cancer. 2013 Jun;12(2):122-7.
Title:	Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer.
Author:	Arienti, Chiara\|Tesei, Anna\|Verdecchia, Giorgio Maria\|Framarini, Massimo\|Virzi, Salvatore\|Grassi, Antonio\|Scarpi, Emanuela\|Turci, Livia\|Silvestrini, Rosella\|Amadori, Dino\|Zoli, Wainer
PMID:	23332421

205.
Journal:	Nucleic Acids Res. 2013 Mar 1;41(5):3047-55.
Title:	The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.
Author:	Senthong, Pattama\|Millington, Christopher L\|Wilkinson, Oliver J\|Marriott, Andrew S\|Watson, Amanda J\|Reamtong, Onrapak\|Eyers, Claire E\|Williams, David M\|Margison, Geoffrey P\|Povey, Andrew C
PMID:	23335782

206.
Journal:	Mod Pathol. 2013 Jun;26(6):825-34.
Title:	Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Walters, Rhiannon J\|Pearson, Sally\|Pavluk, Erika\|Nagler, Belinda\|Pakenas, David\|Jass, Jeremy R\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Parry, Susan\|Hopper, John L\|Giles, Graham G
PMID:	23348904

207.
Journal:	Clin Cancer Res. 2013 Apr 15;19(8):2265-72.
Title:	Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.
Author:	Amatu, Alessio\|Sartore-Bianchi, Andrea\|Moutinho, Catia\|Belotti, Alessandro\|Bencardino, Katia\|Chirico, Giuseppe\|Cassingena, Andrea\|Rusconi, Francesca\|Esposito, Anna\|Nichelatti, Michele\|Esteller, Manel\|Siena, Salvatore
PMID:	23422094

208.
Journal:	Mol Cancer Ther. 2013 May;12(5):809-18.
Title:	A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter.
Author:	Hochhauser, Daniel\|Glynne-Jones, Rob\|Potter, Vanessa\|Gravalos, Cristina\|Doyle, Thomas J\|Pathiraja, Kumudu\|Zhang, Qing\|Zhang, Ling\|Sausville, Edward A
PMID:	23443801

209.
Journal:	PLoS One. 2013;8(4):e60142.
Title:	Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
Author:	Sinha, Rupal\|Hussain, Showket\|Mehrotra, Ravi\|Kumar, R Suresh\|Kumar, Kapil\|Pande, Pankaj\|Doval, Dinesh Chandra\|Basir, Seemi Farhat\|Bharadwaj, Mausumi
PMID:	23573237

210.
Journal:	DNA Cell Biol. 2013 Jul;32(7):371-7.
Title:	Evaluation of methylation of MGMT (O(6)-methylguanine-DNA methyltransferase) gene promoter in sporadic colorectal cancer.
Author:	Farzanehfar, Mohammadreza\|Vossoughinia, Hasan\|Jabini, Raheleh\|Tavassoli, Alireza\|Saadatnia, Hasan\|Khorashad, Ahmad Khosravi\|Ahadi, Mitra\|Afzalaghaee, Monavvar\|Ghayoor Karimiani, Ehsan\|Mirzaei, Farzaneh\|Ayatollahi, Hossein
PMID:	23705976

211.
Journal:	PLoS One. 2013 Jun 13;8(6):e65479.
Title:	PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Sanderson, Kristy\|Walters, Rhiannon J\|Parry, Susan\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Hopper, John L\|Giles, Graham G\|Williamson, Elizabeth J\|English, Dallas R\|Buchanan, Dani
PMID:	23785428

212.
Journal:	Carcinogenesis. 2013 Nov;34(11):2435-42.
Title:	O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer.
Author:	Fahrer, Jorg\|Kaina, Bernd
PMID:	23929436

213.
Journal:	Mol Biol Rep. 2013 Oct;40(10):5921-9.
Title:	Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
Author:	Polakova Vymetalkova, Veronika\|Vannucci, Luca\|Korenkova, Vlasta\|Prochazka, Pavel\|Slyskova, Jana\|Vodickova, Ludmila\|Rusnakova, Vendula\|Bielik, Ludovit\|Burocziova, Monika\|Rossmann, Pavel\|Vodicka, Pavel
PMID:	24065530

214.
Journal:	PLoS One. 2013 Sep 26;8(9):e75367.
Title:	MGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studies.
Author:	Liu, Jun\|Zhang, Renxia\|Chen, Fei\|Yu, Cuicui\|Sun, Yan\|Jia, Chuanliang\|Zhang, Lijing\|Salahuddin, Taufiq\|Li, Xiaodong\|Lang, Juntian\|Song, Xicheng
PMID:	24086516

215.
Journal:	Am J Clin Nutr. 2013 Dec;98(6):1564-74.
Title:	The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.
Author:	Hanks, Joanna\|Ayed, Iyeman\|Kukreja, Neil\|Rogers, Chris\|Harris, Jessica\|Gheorghiu, Alina\|Liu, Chee Ling\|Emery, Peter\|Pufulete, Maria
PMID:	24108782

216.
Journal:	Mutat Res. 2013 Dec 12;758(1-2):80-6.
Title:	Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis.
Author:	Nyskohus, Laura S\|Watson, Amanda J\|Margison, Geoffrey P\|Le Leu, Richard K\|Kim, Susan W\|Lockett, Trevor J\|Head, Richard J\|Young, Graeme P\|Hu, Ying
PMID:	24140386

217.
Journal:	Front Oncol. 2013 Oct 18;3:266.
Title:	Toward a Molecular Classification of Colorectal Cancer: The Role of MGMT.
Author:	Minoo, Parham
PMID:	24151575

218.
Journal:	Oncol Lett. 2013 Nov;6(5):1370-1376.
Title:	Correlation of MLH1 and MGMT methylation levels between peripheral blood leukocytes and colorectal tissue DNA samples in colorectal cancer patients.
Author:	Li, Xia\|Wang, Yibaina\|Zhang, Zuoming\|Yao, Xiaoping\|Ge, Jie\|Zhao, Yashuang
PMID:	24179526

219.
Journal:	Mol Carcinog. 2014 Mar;53(3):201-10.
Title:	Tumor-associated mutations in O(6) -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.
Author:	Lamb, Kristy L\|Liu, Yanfeng\|Ishiguro, Kimiko\|Kwon, Youngho\|Paquet, Nicolas\|Sartorelli, Alan C\|Sung, Patrick\|Rockwell, Sara\|Sweasy, Joann B
PMID:	23065697

220.
Journal:	Tumour Biol. 2014 Mar;35(3):1715-25.
Title:	Two DNA repair gene polymorphisms on the risk of gastrointestinal cancers: a meta-analysis.
Author:	Hu, Yue\|Zhou, Min\|Li, Kang\|Zhang, Kai\|Kong, Xiangquan\|Zheng, Yamei\|Li, Jianxu\|Liu, Li
PMID:	24203816

221.
Journal:	Oncol Rep. 2014 Mar;31(3):1466-72.
Title:	The role of plasma cell-free DNA detection in predicting preoperative chemoradiotherapy response in rectal cancer patients.
Author:	Sun, W\|Sun, Y\|Zhu, M\|Wang, Z\|Zhang, H\|Xin, Y\|Jiang, G\|Guo, X\|Zhang, Z\|Liu, Y
PMID:	24378613

222.
Journal:	Ann Oncol. 2014 Feb;25(2):404-8.
Title:	Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.
Author:	Pietrantonio, F\|Perrone, F\|de Braud, F\|Castano, A\|Maggi, C\|Bossi, I\|Gevorgyan, A\|Biondani, P\|Pacifici, M\|Busico, A\|Gariboldi, M\|Festinese, F\|Tamborini, E\|Di Bartolomeo, M
PMID:	24379162

223.
Journal:	Epigenetics. 2014 Apr;9(4):621-33.
Title:	Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
Author:	Coppede, Fabio\|Migheli, Francesca\|Lopomo, Angela\|Failli, Alessandra\|Legitimo, Annalisa\|Consolini, Rita\|Fontanini, Gabriella\|Sensi, Elisa\|Servadio, Adele\|Seccia, Massimo\|Zocco, Giuseppe\|Chiarugi, Massimo\|Spisni, Roberto\|Migliore, Lucia
PMID:	24500500

224.
Journal:	Genet Test Mol Biomarkers. 2014 Mar;18(3):187-95.
Title:	Association between six genetic polymorphisms and colorectal cancer: a meta-analysis.
Author:	Chen, Cheng\|Wang, Lingyan\|Liao, Qi\|Xu, Leiting\|Huang, Yi\|Zhang, Cheng\|Ye, Huadan\|Xu, Xuting\|Ye, Meng\|Duan, Shiwei
PMID:	24552298

225.
Journal:	J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9.
Title:	Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Author:	Morimoto, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Murakami, Takashi\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	24612059

226.
Journal:	Ann Oncol. 2014 Nov;25(11):2134-46.
Title:	Review of current best practice and priorities for research in radiation oncology for elderly patients with cancer: the International Society of Geriatric Oncology (SIOG) task force.
Author:	Kunkler, I H\|Audisio, R\|Belkacemi, Y\|Betz, M\|Gore, E\|Hoffe, S\|Kirova, Y\|Koper, P\|Lagrange, J-L\|Markouizou, A\|Pfeffer, R\|Villa, S
PMID:	24625455

227.
Journal:	Genes Chromosomes Cancer. 2014 Aug;53(8):703-11.
Title:	Deletion of the MGMT gene in familial melanoma.
Author:	Appelqvist, Frida\|Yhr, Maria\|Erlandson, Anna\|Martinsson, Tommy\|Enerback, Charlotta
PMID:	24801985

228.
Journal:	Gastroenterol Res Pract. 2014;2014:436985.
Title:	Prognostic and predictive value of CpG island methylator phenotype in patients with locally advanced nonmetastatic sporadic colorectal cancer.
Author:	Wang, Yuwei\|Long, Yadong\|Xu, Ye\|Guan, Zuqing\|Lian, Peng\|Peng, Junjie\|Cai, Sanjun\|Cai, Guoxiang
PMID:	24822060

229.
Journal:	BMC Cancer. 2014 Jul 11;14:511.
Title:	Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma.
Author:	Oliver, Jaime Antonio\|Ortiz, Raul\|Melguizo, Consolacion\|Alvarez, Pablo Juan\|Gomez-Millan, Jaime\|Prados, Jose
PMID:	25015560

230.
Journal:	Cancer Prev Res (Phila). 2014 Oct;7(10):1023-34.
Title:	Molecular markers of carcinogenesis for risk stratification of individuals with colorectal polyps: a case-control study.
Author:	Gupta, Samir\|Sun, Han\|Yi, Sang\|Storm, Joy\|Xiao, Guanghua\|Balasubramanian, Bijal A\|Zhang, Song\|Ashfaq, Raheela\|Rockey, Don C
PMID:	25092825

231.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):10050-61.
Title:	IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.
Author:	Naito, Takafumi\|Nosho, Katsuhiko\|Ito, Miki\|Igarashi, Hisayoshi\|Mitsuhashi, Kei\|Yoshii, Shinji\|Aoki, Hironori\|Nomura, Masafumi\|Sukawa, Yasutaka\|Yamamoto, Eiichiro\|Adachi, Yasushi\|Takahashi, Hiroaki\|Hosokawa, Masao\|Fujita, Masahiro\|Takenouchi, Toshinao\|Maru
PMID:	25110432

232.
Journal:	Biomed Res Int. 2014;2014:236361.
Title:	CpG island methylator phenotype and prognosis of colorectal cancer in Northeast China.
Author:	Li, Xia\|Hu, Fulan\|Wang, Yibaina\|Yao, Xiaoping\|Zhang, Zuoming\|Wang, Fan\|Sun, Guizhi\|Cui, Bin-Bin\|Dong, Xinshu\|Zhao, Yashuang
PMID:	25243122

233.
Journal:	World J Clin Cases. 2014 Dec 16;2(12):835-9.
Title:	Role of MGMT as biomarker in colorectal cancer.
Author:	Inno, Alessandro\|Fanetti, Giuseppe\|Di Bartolomeo, Maria\|Gori, Stefania\|Maggi, Claudia\|Cirillo, Massimo\|Iacovelli, Roberto\|Nichetti, Federico\|Martinetti, Antonia\|de Braud, Filippo\|Bossi, Ilaria\|Pietrantonio, Filippo
PMID:	25516857

234.
Journal:	J Nutrigenet Nutrigenomics. 2014;7(4-6):299-313.
Title:	Role of Red Meat and Resistant Starch in Promutagenic Adduct Formation, MGMT Repair, Thymic Lymphoma and Intestinal Tumourigenesis in Msh2 -Deficient Mice.
Author:	Winter, Jean M\|Hu, Ying\|Young, Graeme P\|Kohonen-Corish, Maija R J\|Le Leu, Richard K
PMID:	26022687

235.
Journal:	Oncology. 2015;88(1):28-48.
Title:	N3-substituted temozolomide analogs overcome methylguanine-DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death.
Author:	Zhang, Jihong\|Hummersone, Marc\|Matthews, Charles S\|Stevens, Malcolm F G\|Bradshaw, Tracey D
PMID:	25277441

236.
Journal:	Tumour Biol. 2015 Mar;36(3):1595-601.
Title:	Prognostic value of MGMT methylation in colorectal cancer: a meta-analysis and literature review.
Author:	Li, Yanliang\|Lyu, Zhongchuan\|Zhao, Lixin\|Cheng, Hong\|Zhu, Dongyuan\|Gao, Yongsheng\|Shang, Xiuwan\|Shi, Huaijie
PMID:	25596081

237.
Journal:	Digestion. 2015;91(1):57-63.
Title:	Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Ito, Miki\|Mitsuhashi, Kei\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Yoshii, Shinji\|Mikami, Masashi\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hosokawa, Masao\|Sukawa, Yasutaka\|Adachi, Yasushi\|Hasegawa, Tadashi\|Okita, Kenji\|Hirata, Koi
PMID:	25632919

238.
Journal:	Oncotarget. 2015 Feb 20;6(5):3420-31.
Title:	Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.
Author:	Alonso, Sergio\|Dai, Yuichi\|Yamashita, Kentaro\|Horiuchi, Shina\|Dai, Tomoko\|Matsunaga, Akihiro\|Sanchez-Munoz, Rosa\|Bilbao-Sieyro, Cristina\|Diaz-Chico, Juan Carlos\|Chernov, Andrei V\|Strongin, Alex Y\|Perucho, Manuel
PMID:	25638164

239.
Journal:	Tumour Biol. 2015 Aug;36(8):5839-48.
Title:	Clinicopathological significance and potential drug target of O6-methylguanine-DNA methyltransferase in colorectal cancer: a meta-analysis.
Author:	Zheng, Chen-Guo\|Jin, Chun\|Ye, Le-Chi\|Chen, Nian-Zhao\|Chen, Zong-Jing
PMID:	25716203

240.
Journal:	Asian Pac J Cancer Prev. 2015;16(5):1945-52.
Title:	MGMT-B gene promoter hypermethylation in patients with inflammatory bowel disease - a novel finding.
Author:	Mokarram, Pooneh\|Kavousipour, Soudabeh\|Sarabi, Mostafa Moradi\|Mehrabani, Golnosh\|Fahmidehkar, Mohammad Ali\|Shamsdin, Seyedeh Azra\|Alipour, Abbas\|Naini, Mahvash Alizade
PMID:	25773792

241.
Journal:	Int J Clin Exp Med. 2015 Jan 15;8(1):791-9. eCollection 2015.
Title:	The role of O(6)-methylguanine-DNA methyltransferase polymorphisms in colorectal cancer susceptibility: a meta analysis.
Author:	Lu, Yongchao\|Cao, Mingfeng\|Gao, Kejian\|Jiang, Jinjiao\|Shi, Xuewen
PMID:	25785059

242.
Journal:	PLoS One. 2015 Mar 27;10(3):e0123396.
Title:	DNA methylation combinations in adjacent normal colon tissue predict cancer recurrence: evidence from a clinical cohort study.
Author:	Kuan, Jen Chun\|Wu, Chang Chieh\|Sun, Chien An\|Chu, Chi Ming\|Lin, Fu Gong\|Hsu, Chih Hsiung\|Kan, Po-Chieh\|Lin, Shih-Chieh\|Yang, Tsan\|Chou, Yu-Ching
PMID:	25815725

243.
Journal:	Future Oncol. 2015;11(8):1201-9.
Title:	MGMT promoter methylation status in brain metastases from colorectal cancer and corresponding primary tumors.
Author:	De Maglio, Giovanna\|Casagrande, Mariaelena\|Guardascione, Michela\|Fontanella, Caterina\|Lutrino, Stefania Eufemia\|Rihawi, Karim\|Pisa, Federica Edith\|Tuniz, Francesco\|Fasola, Gianpiero\|Pizzolitto, Stefano\|Aprile, Giuseppe
PMID:	25832877

244.
Journal:	Exp Biol Med (Maywood). 2015 Dec;240(12):1599-605.
Title:	Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma.
Author:	Michailidi, Christina\|Theocharis, Stamatios\|Tsourouflis, Gerasimos\|Pletsa, Vasiliki\|Kouraklis, Gregorios\|Patsouris, Efstratios\|Papavassiliou, Athanasios G\|Troungos, Constantinos
PMID:	25908636

245.
Journal:	Epigenomics. 2015;7(2):175-86.
Title:	Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer.
Author:	Coppede, Fabio\|Grossi, Enzo\|Lopomo, Angela\|Spisni, Roberto\|Buscema, Massimo\|Migliore, Lucia
PMID:	25942531

246.
Journal:	Carcinogenesis. 2015 Aug;36(8):817-31.
Title:	Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
Author:	Goder, Anja\|Nagel, Georg\|Kraus, Alexander\|Dorsam, Bastian\|Seiwert, Nina\|Kaina, Bernd\|Fahrer, Jorg
PMID:	25998848

247.
Journal:	Int J Oncol. 2015 Aug;47(2):764-72.
Title:	Influence of fatty acid synthase inhibitor orlistat on the DNA repair enzyme O6-methylguanine-DNA methyltransferase in human normal or malignant cells in vitro.
Author:	Cioccoloni, Giorgia\|Bonmassar, Laura\|Pagani, Elena\|Caporali, Simona\|Fuggetta, Maria Pia\|Bonmassar, Enzo\|D'Atri, Stefania\|Aquino, Angelo
PMID:	26035182

248.
Journal:	Carcinogenesis. 2015 Oct;36(10):1235-44.
Title:	DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
Author:	Fahrer, Jorg\|Frisch, Janina\|Nagel, Georg\|Kraus, Alexander\|Dorsam, Bastian\|Thomas, Adam D\|Reissig, Sonja\|Waisman, Ari\|Kaina, Bernd
PMID:	26243310

249.
Journal:	Oncotarget. 2015 Nov 10;6(35):38139-50.
Title:	miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1.
Author:	Chen, Zhiheng\|Liu, Shaojun\|Tian, Li\|Wu, Minghao\|Ai, Feiyan\|Tang, Wuliang\|Zhao, Lian\|Ding, Juan\|Zhang, Liyang\|Tang, Anliu
PMID:	26497367

250.
Journal:	Cytogenet Genome Res. 2015;146(4):261-7.
Title:	Colorectal Cancers with the Uncommon Findings of KRAS Mutation and Microsatellite Instability.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	26523369

251.
Journal:	Cancer Biol Ther. 2015;16(12):1726-37.
Title:	Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
Author:	El-Deiry, Wafik S\|Vijayvergia, Namrata\|Xiu, Joanne\|Scicchitano, Angelique\|Lim, Bora\|Yee, Nelson S\|Harvey, Harold A\|Gatalica, Zoran\|Reddy, Sandeep
PMID:	26553611

252.
Journal:	Histopathology. 2016 Mar;68(4):578-87.
Title:	Serrated tubulovillous adenoma of the large intestine.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Klein, Kerenaftali\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26212352

253.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1472-81.
Title:	The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.
Author:	Renaud, Florence\|Mariette, Christophe\|Vincent, Audrey\|Wacrenier, Agnes\|Maunoury, Vincent\|Leclerc, Julie\|Coppin, Lucie\|Crepin, Michel\|Van Seuningen, Isabelle\|Leteurtre, Emmanuelle\|Buisine, Marie-Pierre
PMID:	26476272

254.
Journal:	Target Oncol. 2016 Jun;11(3):337-43.
Title:	Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer.
Author:	Pietrantonio, Filippo\|de Braud, Filippo\|Milione, Massimo\|Maggi, Claudia\|Iacovelli, Roberto\|Dotti, Katia Fiorella\|Perrone, Federica\|Tamborini, Elena\|Caporale, Marta\|Berenato, Rosa\|Leone, Giorgia\|Pellegrinelli, Alessio\|Bossi, Ilaria\|Festinese, Fabrizio\|Fede
PMID:	26538496

255.
Journal:	Front Biosci (Elite Ed). 2016 Jan 1;8:170-80.
Title:	Pharmacoepigenetics in gastrointestinal tumors: MGMT methylation and beyond.
Author:	Fornaro, Lorenzo\|Vivaldi, Caterina\|Caparello, Chiara\|Musettini, Gianna\|Baldini, Editta\|Masi, Gianluca\|Falcone, Alfredo
PMID:	26709653

256.
Journal:	Carcinogenesis. 2016 Feb;37(2):206-14.
Title:	Homeostatic responses of colonic LGR5+ stem cells following acute in vivo exposure to a genotoxic carcinogen.
Author:	Kim, Eunjoo\|Davidson, Laurie A\|Zoh, Roger S\|Hensel, Martha E\|Patil, Bhimanagouda S\|Jayaprakasha, Guddadarangavvanahally K\|Callaway, Evelyn S\|Allred, Clinton D\|Turner, Nancy D\|Weeks, Brad R\|Chapkin, Robert S
PMID:	26717997

257.
Journal:	Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2911-5.
Title:	Chemoproteomics-Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT.
Author:	Wang, Chao\|Abegg, Daniel\|Hoch, Dominic G\|Adibekian, Alexander
PMID:	26798972

258.
Journal:	Oncotarget. 2016 Mar 1;7(9):10322-31.
Title:	Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC.
Author:	Scarpa, Marco\|Scarpa, Melania\|Castagliuolo, Ignazio\|Erroi, Francesca\|Kotsafti, Andromachi\|Basato, Silvia\|Brun, Paola\|D'Inca, Renata\|Rugge, Massimo\|Angriman, Imerio\|Castoro, Carlo
PMID:	26862732

259.
Journal:	Oncotarget. 2016 Jun 14;7(24):37331-37346.
Title:	The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer.
Author:	Gao, Dan\|Herman, James G\|Guo, Mingzhou
PMID:	26967246

260.
Journal:	Tumour Biol. 2016 Aug;37(8):11443-56.
Title:	MGMT in colorectal cancer: a promising component of personalized treatment.
Author:	Zhang, Le\|Zeng, Jing\|Zeng, Zhaolei\|Wang, Fenghua\|Wang, Deshen\|Chen, Cui\|Li, Cong\|An, Xin\|Xu, Ruihua\|Huang, Peng\|Ba, Yi\|Li, Yuhong
PMID:	27006309

261.
Journal:	Virchows Arch. 2016 Aug;469(2):135-44.
Title:	Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Author:	Boissiere-Michot, Florence\|Frugier, Helene\|Ho-Pun-Cheung, Alexandre\|Lopez-Crapez, Evelyne\|Duffour, Jacqueline\|Bibeau, Frederic
PMID:	27220764

262.
Journal:	Asian Pac J Cancer Prev. 2016;17(4):2185-93.
Title:	Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps.
Author:	Naini, M Alizade\|Mokarram, P\|Kavousipour, S\|Zare, N\|Atapour, A\|Zarin1, M Hassan\|Mehrabani, G\|Borji, M
PMID:	27221916

263.
Journal:	Carcinogenesis. 2016 Aug;37(8):751-8.
Title:	Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC).
Author:	Xicola, Rosa M\|Bontu, Sneha\|Doyle, Brian J\|Rawson, Jamie\|Garre, Pilar\|Lee, Esther\|de la Hoya, Miguel\|Bessa, Xavier\|Clofent, Joan\|Bujanda, Luis\|Balaguer, Francesc\|Castellvi-Bel, Sergi\|Alenda, Cristina\|Jover, Rodrigo\|Ruiz-Ponte, Clara\|Syngal, Sapna\|Andreu,
PMID:	27234654

264.
Journal:	Clin Cancer Res. 2016 Dec 15;22(24):6266-6277.
Title:	SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer.
Author:	Kuroiwa-Trzmielina, Joice\|Wang, Fan\|Rapkins, Robert W\|Ward, Robyn L\|Buchanan, Daniel D\|Win, Aung Ko\|Clendenning, Mark\|Rosty, Christophe\|Southey, Melissa C\|Winship, Ingrid M\|Hopper, John L\|Jenkins, Mark A\|Olivier, Jake\|Hawkins, Nicholas J\|Hitchins, Megan P
PMID:	27267851

265.
Journal:	Int J Mol Med. 2016 Sep;38(3):687-702.
Title:	Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.
Author:	Silva, Patricia\|Albuquerque, Cristina\|Lage, Pedro\|Fontes, Vanessa\|Fonseca, Ricardo\|Vitoriano, Ines\|Filipe, Bruno\|Rodrigues, Paula\|Moita, Susana\|Ferreira, Sara\|Sousa, Rita\|Claro, Isabel\|Nobre Leitao, Carlos\|Chaves, Paula\|Dias Pereira, Antonio
PMID:	27430658

266.
Journal:	Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):289-295.
Title:	Phase 1 Study of Preoperative Chemoradiation Therapy With Temozolomide and Capecitabine in Patients With Locally Advanced Rectal Cancer.
Author:	Jeong, Jae Ho\|Hong, Yong Sang\|Park, Yangsoon\|Kim, Jihun\|Kim, Jeong Eun\|Kim, Kyu-Pyo\|Kim, Sun Young\|Park, Jin-Hong\|Kim, Jong Hoon\|Park, In Ja\|Lim, Seok-Byung\|Yu, Chang Sik\|Kim, Jin Cheon\|Kim, Tae Won
PMID:	27473815

267.
Journal:	Cancer Biomark. 2016 Jun 24;17(2):133-43.
Title:	KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
Author:	Bagci, Binnur\|Sari, Musa\|Karadayi, Kursat\|Turan, Mustafa\|Ozdemir, Ozturk\|Bagci, Gokhan
PMID:	27540971

268.
Journal:	Tumori. 2016 Dec 1;102(6):541-547.
Title:	How the lab is changing our view of colorectal cancer.
Author:	Cremolini, Chiara\|Pietrantonio, Filippo
PMID:	27647226

269.
Journal:	Anticancer Res. 2016 Oct;36(10):5315-5324.
Title:	KRAS Mutant Status, p16 and beta-catenin Expression May Predict Local Recurrence in Patients Who Underwent Transanal Endoscopic Microsurgery (TEMS) for Stage I Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Bjarnason, Ingvar\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	27798894

270.
Journal:	Gut. 2017 Jan;66(1):97-106.
Title:	Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26475632

271.
Journal:	Food Chem Toxicol. 2017 Aug;106(Pt B):583-594.
Title:	Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens.
Author:	Fahrer, Jorg\|Kaina, Bernd
PMID:	27693244

272.
Journal:	Avicenna J Med Biotechnol. 2017 Jan-Mar;9(1):13-18.
Title:	Induction of Epigenetic Alteration by CPUK02, An Ent- kaurenoid Derivative of Stevioside.
Author:	Mokarram, Pooneh\|Mohammadi, Zeinab\|Khazayel, Saeid\|Dayong, Zhang
PMID:	28090275

273.
Journal:	Cancer Invest. 2017 Feb 7;35(2):116-121.
Title:	Promoter Hypermethylation and Its Impact on Expression of MGMT Gene in the GIT Malignant Patients of Kashmiri Origin.
Author:	Bhat, Arif Akbar\|Wani, Hilal Ahmad\|Ishaq, Shiekh\|Waza, Ajaz Ahmad\|Malik, Rawoof Ahmad\|Shabir, Iram\|Jeelani, Showkat\|Kadla, Showkat\|Qureshie, Waseem\|Masood, Akbar\|Majid, Sabhiya
PMID:	28135856

274.
Journal:	BMC Cell Biol. 2017 Feb 27;18(1):14.
Title:	Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells.
Author:	Seo, Jung Seon\|Choi, Young Ha\|Moon, Ji Wook\|Kim, Hyeon Soo\|Park, Sun-Hwa
PMID:	28241740

275.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

276.
Journal:	Anticancer Res. 2017 Mar;37(3):1349-1357.
Title:	KRAS Mutant Status May Be Associated with Distant Recurrence in Early-stage Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	28314302

277.
Journal:	Br J Cancer. 2017 May 9;116(10):1279-1286.
Title:	A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Author:	Calegari, M A\|Inno, A\|Monterisi, S\|Orlandi, A\|Santini, D\|Basso, M\|Cassano, A\|Martini, M\|Cenci, T\|de Pascalis, I\|Camarda, F\|Barbaro, B\|Larocca, L M\|Gori, S\|Tonini, G\|Barone, C
PMID:	28427088

278.
Journal:	Mod Pathol. 2017 Aug;30(8):1177-1189.
Title:	Mapping clinicopathological entities within colorectal mucinous adenocarcinomas: a hierarchical clustering approach.
Author:	Liddell, Charly\|Droy-Dupre, Laure\|Metairie, Sylvie\|Airaud, Fabrice\|Volteau, Christelle\|Bezieau, Stephane\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	28429715

279.
Journal:	J Biomed Phys Eng. 2017 Mar 1;7(1):79-86. eCollection 2017 Mar.
Title:	Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats.
Author:	Mokarram, P\|Sheikhi, M\|Mortazavi, S M J\|Saeb, S\|Shokrpour, N
PMID:	28451581

280.
Journal:	Yonsei Med J. 2017 Jul;58(4):749-755.
Title:	Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer.
Author:	Sambuudash, Otgontuya\|Kim, Hyun Soo\|Cho, Mee Yon
PMID:	28540987

281.
Journal:	Clin Transl Gastroenterol. 2017 Jul 27;8(7):e109.
Title:	The Association of Low-Penetrance Variants in DNA Repair Genes with Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author:	Aggarwal, Nikhil\|Donald, Neil D\|Malik, Salim\|Selvendran, Subothini S\|McPhail, Mark Jw\|Monahan, Kevin J
PMID:	28749454

282.
Journal:	Gene. 2018 Feb 20;644:66-73.
Title:	Promoter methylation and expression of DNA repair genes MGMT and ERCC1 in tissue and blood of rectal cancer patients.
Author:	Shalaby, Sally M\|El-Shal, Amal S\|Abdelaziz, Lobna A\|Abd-Elbary, Eman\|Khairy, Mostafa M
PMID:	29080834

283.
Journal:	J Cell Biochem. 2018 Jul;119(7):5350-5358.
Title:	Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells.
Author:	Yang, Zhikuan\|Wei, Danping\|Liu, Feifei\|Liu, Jing\|Wu, Xiaoming\|Stevens, Malcolm F G\|Bradshaw, Tracey D\|Luo, Ying\|Zhang, Jihong
PMID:	29331023

284.
Journal:	Oncol Lett. 2018 Mar;15(3):3586-3593.
Title:	Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer.
Author:	Toth, Csaba\|Sukosd, Farkas\|Valicsek, Erzsebet\|Herpel, Esther\|Schirmacher, Peter\|Tiszlavicz, Laszlo
PMID:	29467879

285.
Journal:	J Transl Med. 2018 Feb 27;16(1):45.
Title:	A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.
Author:	Freitas, Micaela\|Ferreira, Fabio\|Carvalho, Sonia\|Silva, Fernanda\|Lopes, Paula\|Antunes, Luis\|Salta, Sofia\|Diniz, Francisca\|Santos, Lucio Lara\|Videira, Jose Flavio\|Henrique, Rui\|Jeronimo, Carmen
PMID:	29486770

286.
Journal:	Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070.
Title:	PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.
Author:	Dorsam, Bastian\|Seiwert, Nina\|Foersch, Sebastian\|Stroh, Svenja\|Nagel, Georg\|Begaliew, Diana\|Diehl, Erika\|Kraus, Alexander\|McKeague, Maureen\|Minneker, Vera\|Roukos, Vassilis\|Reissig, Sonja\|Waisman, Ari\|Moehler, Markus\|Stier, Anna\|Mangerich, Aswin\|Dantzer, F
PMID:	29632181

287.
Journal:	Asian Pac J Cancer Prev. 2018 May 26;19(5):1223-1227.
Title:	O6-Methyguanine-DNA Methyl Transferase (MGMT) Promoter Methylation in Serum DNA of Iranian Patients with Colorectal Cancer
Author:	Alizadeh Naini, Mahvash\|Kavousipour, Soudabeh\|Hasanzarini, Maryam\|Nasrollah, Amir\|Monabati, Ahmad\|Mokarram, Pooneh
PMID:	29801405

288.
Journal:	Ann Oncol. 2018 Aug 1;29(8):1800-1806.
Title:	Temozolomide and irinotecan (TEMIRI regimen) as salvage treatment of irinotecan-sensitive advanced colorectal cancer patients bearing MGMT methylation.
Author:	Morano, F\|Corallo, S\|Niger, M\|Barault, L\|Milione, M\|Berenato, R\|Moretto, R\|Randon, G\|Antista, M\|Belfiore, A\|Raimondi, A\|Nichetti, F\|Martinetti, A\|Battaglia, L\|Perrone, F\|Pruneri, G\|Falcone, A\|Di Bartolomeo, M\|de Braud, F\|Di Nicolantonio, F\|Cremolini, C\|Pi
PMID:	29860358

289.
Journal:	Eur J Cancer Prev. 2018 Oct 30.
Title:	Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer.
Author:	Wani, Hilal A\|Majid, Sabhiya\|Bhat, Arif A\|Amin, Shajrul\|Farooq, Rabia\|Bhat, Showkat A\|Naikoo, Nissar A\|Beigh, Mushtaq A\|Kadla, Showkat A
PMID:	30379684