Primary Site >> Biliary tract Cancer

Gene >> MGMT

Journal: Ann Surg Oncol. 2002 May;9(4):371-9.
Title: Deficient expression of O(6)-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma.
Author: Kohya, Naohiko|Miyazaki, Kohji|Matsukura, Shiroh|Yakushiji, Hiroyuki|Kitajima, Yoshihiko|Kitahara, Kenji|Fukuhara, Masao|Nakabeppu, Yusaku|Sekiguchi, Mutsuo
PMID: 11986189
Journal: Am J Pathol. 2002 Sep;161(3):1015-22.
Title: Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma.
Author: Lee, Sun|Kim, Woo Ho|Jung, Hwoon-Yong|Yang, Moon Ho|Kang, Gyeong Hoon
PMID: 12213730
Journal: Int J Mol Med. 2003 Jan;11(1):65-9.
Title: Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma.
Author: Kohya, Naohiko|Kitajima, Yoshihiko|Kitahara, Kenji|Miyazaki, Kohji
PMID: 12469220
Journal: Gastroenterology. 2003 May;124(5):1300-10.
Title: Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas.
Author: Kim, Sang Geol|Chan, Annie On-On|Wu, Tsung-Teh|Issa, Jean-Pierre J|Hamilton, Stanley R|Rashid, Asif
PMID: 12730870
Journal: Mod Pathol. 2005 Mar;18(3):412-20.
Title: Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma.
Author: Yang, Bin|House, Michael G|Guo, Mingzhou|Herman, James G|Clark, Douglas P
PMID: 15467712
Journal: Oncol Rep. 2005 May;13(5):899-906.
Title: Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
Author: Sato, Ken|Kitajima, Yoshihiko|Nakagawachi, Tetsuji|Soejima, Hidenobu|Miyoshi, Atsushi|Koga, Yasuo|Miyazaki, Kohji
PMID: 15809756
Journal: Int J Oncol. 2005 Jun;26(6):1653-61.
Title: Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest.
Author: Sato, Ken|Kitajima, Yoshihiko|Kohya, Naohiko|Miyoshi, Atsushi|Koga, Yasuo|Miyazaki, Kohji
PMID: 15870882
Journal: Ann Surg Oncol. 2005 May;12(5):354-63. Epub 2005 Mar 31.
Title: Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers.
Author: Koga, Yasuo|Kitajima, Yoshihiko|Miyoshi, Atsushi|Sato, Ken|Kitahara, Kenji|Soejima, Hidenobu|Miyazaki, Kohji
PMID: 15915369
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4021-8.
Title: The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
Author: Sato, Ken|Kitajima, Yoshihiko|Koga, Yasuo|Miyazaki, Kohji
PMID: 16309194
Journal: Arch Pathol Lab Med. 2007 Jun;131(6):923-30.
Title: Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas.
Author: Kim, Baek-Hee|Cho, Nam-Yun|Choi, Minhee|Lee, Sun|Jang, Ja June|Kang, Gyeong Hoon
PMID: 17550320
Journal: Pathol Oncol Res. 2007;13(4):326-35. Epub 2007 Dec 25.
Title: Significance of PML and p53 protein as molecular prognostic markers of gallbladder carcinomas.
Author: Chang, Hee Jin|Yoo, Byong Chul|Kim, Sun Whe|Lee, Byung Lan|Kim, Woo Ho
PMID: 18158568
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2123-7.
Title: Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in China.
Author: Zhang, Mingdong|Huang, Wen-Yi|Andreotti, Gabriella|Gao, Yu-Tang|Rashid, Asif|Chen, Jinbo|Sakoda, Lori C|Shen, Ming-Chang|Wang, Bing-Sheng|Chanock, Stephen|Hsing, Ann W
PMID: 18708406
Journal: Mol Carcinog. 2009 Jan;48(1):79-89.
Title: Promoter methylation profile in preneoplastic and neoplastic gallbladder lesions.
Author: Garcia, Patricia|Manterola, Carlos|Araya, Juan Carlos|Villaseca, Miguel|Guzman, Pablo|Sanhueza, Antonio|Thomas, Melanie|Alvarez, Hector|Roa, Juan Carlos
PMID: 18543280
Journal: HPB (Oxford). 2015 Dec;17(12):1119-23.
Title: Intrahepatic cholangiocarcinoma and gallbladder cancer: distinguishing molecular profiles to guide potential therapy.
Author: Potkonjak, Mary|Miura, John T|Turaga, Kiran K|Johnston, Fabian M|Tsai, Susan|Christians, Kathleen K|Gamblin, T Clark
PMID: 26374242