Primary Site >> Stomach Cancer

Gene >> MET

Journal: Oncogene. 1989 Nov;4(11):1383-8.
Title: Biosynthesis of the protein encoded by the c-met proto-oncogene.
Author: Giordano, S|Di Renzo, M F|Narsimhan, R P|Cooper, C S|Rosa, C|Comoglio, P M
PMID: 2554238
Journal: Oncogene. 1990 May;5(5):721-5.
Title: Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein.
Author: Gandino, L|Di Renzo, M F|Giordano, S|Bussolino, F|Comoglio, P M
PMID: 2111905
Journal: Cancer Res. 1990 Oct 1;50(19):6417-22.
Title: Gene amplification in gastric and esophageal adenocarcinomas.
Author: Houldsworth, J|Cordon-Cardo, C|Ladanyi, M|Kelsen, D P|Chaganti, R S
PMID: 2400999
Journal: J Biol Chem. 1991 Oct 15;266(29):19558-64.
Title: Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase.
Author: Ferracini, R|Longati, P|Naldini, L|Vigna, E|Comoglio, P M
PMID: 1655790
Journal: Oncogene. 1991 Apr;6(4):553-9.
Title: c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase.
Author: Ponzetto, C|Giordano, S|Peverali, F|Della Valle, G|Abate, M L|Vaula, G|Comoglio, P M
PMID: 1674365
Journal: Biochem Biophys Res Commun. 1992 Nov 30;189(1):227-32.
Title: Frequent amplification of the c-met gene in scirrhous type stomach cancer.
Author: Kuniyasu, H|Yasui, W|Kitadai, Y|Yokozaki, H|Ito, H|Tahara, E
PMID: 1333188
Journal: Cancer Genet Cytogenet. 1992 Dec;64(2):170-3.
Title: Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
Author: Rege-Cambrin, G|Scaravaglio, P|Carozzi, F|Giordano, S|Ponzetto, C|Comoglio, P M|Saglio, G
PMID: 1486568
Journal: Gan To Kagaku Ryoho. 1993 Feb;20(3):326-31.
Title: [Metastasis related genes and malignancy in human esophageal, gastric and colorectal cancers].
Author: Tahara, E|Kuniyasu, H|Nakayama, H|Yasui, W|Yokozaki, H
PMID: 8094950
Journal: Int J Cancer. 1993 Aug 19;55(1):72-5.
Title: Aberrant expression of c-met mRNA in human gastric carcinomas.
Author: Kuniyasu, H|Yasui, W|Yokozaki, H|Kitadai, Y|Tahara, E
PMID: 8344755
Journal: J Cancer Res Clin Oncol. 1993;119(5):265-72.
Title: Molecular mechanism of stomach carcinogenesis.
Author: Tahara, E
PMID: 8440743
Journal: Cell Growth Differ. 1993 Apr;4(4):291-6.
Title: GC factor represses transcription of several growth factor/receptor genes and causes growth inhibition of human gastric carcinoma cell lines.
Author: Kitadai, Y|Yamazaki, H|Yasui, W|Kyo, E|Yokozaki, H|Kajiyama, G|Johnson, A C|Pastan, I|Tahara, E
PMID: 8494791
Journal: Int J Oncol. 1993 Jul;3(1):89-93.
Title: Biologic effect of human hepatocyte growth-factor on human gastric-carcinoma cell-lines.
Author: Yokozaki, H|Ito, M|Yasui, W|Kyo, E|Kuniyasu, H|Kitadai, Y|Tsubouchi, H|Daikuhara, Y|Tahara, E
PMID: 21573331
Journal: Int J Oncol. 1993 Dec;3(6):1067-70.
Title: Expression of hepatocyte growth factor(hgf) and C-met gene in human gastric-cancer cell-lines.
Author: Fushida, S|Yonemura, Y|Urano, T|Yamaguchi, A|Miyazaki, I|Nakamura, T|Shiku, H
PMID: 21573474
Journal: Gan To Kagaku Ryoho. 1994 Nov;21(15):2541-8.
Title: [Metastasis-related genes].
Author: Yokozaki, H|Tahara, E
PMID: 7526801
Journal: Gan To Kagaku Ryoho. 1994 Oct;21(14):2371-7.
Title: [Genetic characteristics of scirrhous gastric carcinomas].
Author: Yokozaki, H|Kuniyasu, H|Yasui, W|Tahara, E
PMID: 7944479
Journal: Virchows Arch. 1994;425(2):139-44.
Title: Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines.
Author: Tannapfel, A|Yasui, W|Yokozaki, H|Wittekind, C|Tahara, E
PMID: 7952499
Journal: Int J Cancer. 1994 Dec 1;59(5):597-600.
Title: Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas.
Author: Kuniyasu, H|Yasui, W|Yokozaki, H|Akagi, M|Akama, Y|Kitahara, K|Fujii, K|Tahara, E
PMID: 7960231
Journal: Leuk Res. 1994 Jan;18(1):7-16.
Title: The Met/hepatocyte growth factor receptor (HGFR) gene is overexpressed in some cases of human leukemia and lymphoma.
Author: Jucker, M|Gunther, A|Gradl, G|Fonatsch, C|Krueger, G|Diehl, V|Tesch, H
PMID: 8289471
Journal: Princess Takamatsu Symp. 1994;24:187-94.
Title: Cancer-stromal interaction through growth factor/cytokine networks implicated in growth of stomach cancer.
Author: Tahara, E
PMID: 8983075
Journal: World J Surg. 1995 Jul-Aug;19(4):484-8; discussion 489-90.
Title: Molecular biology of gastric cancer.
Author: Tahara, E
PMID: 7676688
Journal: Dig Dis Sci. 1995 May;40(5):1132-9.
Title: Roles of hepatocyte growth factor and its receptor in gastric mucosa. A cell biological and molecular biological study.
Author: Tsuji, S|Kawano, S|Tsujii, M|Fusamoto, H|Kamada, T
PMID: 7729276
Journal: Cancer. 1995 Mar 15;75(6 Suppl):1410-7.
Title: Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosis.
Author: Tahara, E
PMID: 7889467
Journal: Eur J Biochem. 1996 Mar 1;236(2):476-81.
Title: Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells.
Author: Nagamine, K|Shibamoto, S|Takeuchi, K|Miyazawa, K|Kitamura, N|Chatani, Y|Kohno, M|Ito, F
PMID: 8612619
Journal: Nihon Geka Gakkai Zasshi. 1996 Apr;97(4):252-6.
Title: [Genetic alterations in stomach cancer].
Author: Tahara, E|Yasui, W|Yokozaki, H
PMID: 8692139
Journal: Zhonghua Zhong Liu Za Zhi. 1996 Jan;18(1):6-9.
Title: [Activation of proto-oncogenes induced by MNNG on primary culture of human gastric epithelium and immortalized human gastric epithelial cell line].
Author: Wang, B|Su, X|Ke, Y
PMID: 8732101
Journal: Nihon Rinsho. 1996 Apr;54(4):1066-71.
Title: [Multistep stomach carcinogenesis].
Author: Yokozaki, H|Tahara, E
PMID: 8920675
Journal: Cancer Gene Ther. 1996 Nov-Dec;3(6):393-404.
Title: Participation of c-met in the progression of human gastric cancers: anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells.
Author: Kaji, M|Yonemura, Y|Harada, S|Liu, X|Terada, I|Yamamoto, H
PMID: 8988842
Journal: Zhonghua Yi Xue Za Zhi. 1996 May;76(5):359-62.
Title: [The overexpression of c-met oncogene correlation with gastric mucosal lesion].
Author: Wang, J|Lu, Y|Li, J
PMID: 9206200
Journal: Shi Yan Sheng Wu Xue Bao. 1996 Mar;29(1):13-23.
Title: [Studies on the phenotype deviation of the single-cell subclones of human stomach carcinoma MGC-803 cell line].
Author: Han, Y L|Zhang, Z Q|Cai, X F|Zhang, W J|Lin, Z X
PMID: 9208638
Journal: Zhonghua Yi Xue Za Zhi. 1996 Sep;76(9):671-5.
Title: [Correlation of multiple gene changes with malignant phenotype of human gastric carcinoma].
Author: Gao, C|Lu, Y
PMID: 9275549
Journal: Int J Oncol. 1996 Mar;8(3):555-60.
Title: Correlation between overexpression of c-met gene and the progression of gastric cancer.
Author: Yonemura, Y|Kaji, M|Hirono, Y|Fushida, S|Tsugawa, K|Fujimura, T|Miyazaki, I|Harada, S|Yamamoto, H
PMID: 21544396
Journal: Oncol Rep. 1996 May;3(3):425-8.
Title: A splice variant of the c-met proto-oncogene is the predominant population expressed in human gastric mucosa and carcinoma.
Author: Yokozaki, H|Semba, S|Yamamoto, S|Tahara, E
PMID: 21594385
Journal: Jpn J Cancer Res. 1997 Feb;88(2):152-9.
Title: Transforming growth factor-beta and hepatocyte growth factor produced by gastric fibroblasts stimulate the invasiveness of scirrhous gastric cancer cells.
Author: Inoue, T|Chung, Y S|Yashiro, M|Nishimura, S|Hasuma, T|Otani, S|Sowa, M
PMID: 9119743
Journal: Gastroenterology. 1997 May;112(5):1457-65.
Title: Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection.
Author: Wu, M S|Shun, C T|Wang, H P|Sheu, J C|Lee, W J|Wang, T H|Lin, J T
PMID: 9136822
Journal: Anticancer Res. 1997 Sep-Oct;17(5A):3575-80.
Title: Effect of hepatocyte growth factor on cell cycle and c-met expression in human gastric cancer cells.
Author: Liu, S I|Lui, W Y|Mok, K T|Wu, C W|Chi, C W
PMID: 9413205
Journal: Virchows Arch. 1997 Dec;431(6):383-9.
Title: Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer.
Author: Tsujimoto, H|Sugihara, H|Hagiwara, A|Hattori, T
PMID: 9428926
Journal: Oncol Rep. 1997 Jul-Aug;4(4):743-8.
Title: E-cadherin and c-met expression as a prognostic factor in gastric cancer.
Author: Yonemura, Y|Nojima, N|Kaji, M|Kawamura, T|Fushida, S|Fujimura, T|Itoh, H|Fujita, H|Miyazaki, J|Endou, Y|Sasaki, T|Yamamoto, H
PMID: 21590132
Journal: Cancer. 1998 Jun 1;82(11):2112-22.
Title: The relation between the growth patterns of gastric carcinoma and the expression of hepatocyte growth factor receptor (c-met), autocrine motility factor receptor, and urokinase-type plasminogen activator receptor.
Author: Taniguchi, K|Yonemura, Y|Nojima, N|Hirono, Y|Fushida, S|Fujimura, T|Miwa, K|Endo, Y|Yamamoto, H|Watanabe, H
PMID: 9610690
Journal: Mod Pathol. 1998 Jun;11(6):552-9.
Title: Prostatic carcinoma with signet ring cells: a clinicopathologic and immunohistochemical analysis of 12 cases, with review of the literature.
Author: Torbenson, M|Dhir, R|Nangia, A|Becich, M J|Kapadia, S B
PMID: 9647593
Journal: Oncology. 1998 Sep-Oct;55(5):475-81.
Title: Amplification of the c-met, c-erbB-2 and epidermal growth factor receptor gene in human gastric cancers: correlation to clinical features.
Author: Tsugawa, K|Yonemura, Y|Hirono, Y|Fushida, S|Kaji, M|Miwa, K|Miyazaki, I|Yamamoto, H
PMID: 9732228
Journal: Lab Invest. 1998 Sep;78(9):1143-53.
Title: Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization.
Author: Hara, T|Ooi, A|Kobayashi, M|Mai, M|Yanagihara, K|Nakanishi, I
PMID: 9759658
Journal: Jpn J Cancer Res. 1998 Aug;89(8):829-36.
Title: Expression of cadherin-catenin cell adhesion molecules, phosphorylated tyrosine residues and growth factor receptor-tyrosine kinases in gastric cancers.
Author: Akimoto, S|Ochiai, A|Inomata, M|Hirohashi, S
PMID: 9765619
Journal: Gan To Kagaku Ryoho. 1998 Nov;25(13):2021-7.
Title: [New molecular prognostic markers in gastric carcinoma].
Author: Yoshida, K|Yasui, W|Yokozaki, H|Nishimoto, N|Kagawa, Y|Toge, T|Tahara, E|Yoshida, T|Terada, M
PMID: 9838902
Journal: Zhonghua Yi Xue Za Zhi. 1998 Jul;78(7):488-9.
Title: [The relationship between Helicobacter pylori and expression of c-met oncogene in gastric precancerous lesions].
Author: Guo, F|Hu, F|Jia, B
PMID: 10923453
Journal: Cancer. 1999 May 1;85(9):1894-902.
Title: The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas.
Author: Nakajima, M|Sawada, H|Yamada, Y|Watanabe, A|Tatsumi, M|Yamashita, J|Matsuda, M|Sakaguchi, T|Hirao, T|Nakano, H
PMID: 10223227
Journal: Biochem Biophys Res Commun. 1999 Nov 19;265(2):453-6.
Title: PPARgamma inhibits the expression of c-MET in human gastric cancer cells through the suppression of Ets.
Author: Kitamura, S|Miyazaki, Y|Hiraoka, S|Toyota, M|Nagasawa, Y|Kondo, S|Kiyohara, T|Shinomura, Y|Matsuzawa, Y
PMID: 10558888
Journal: Zhonghua Zhong Liu Za Zhi. 1999 Sep;21(5):339-41.
Title: [Gene detection and localization by FISH with short DNA fragment cloned in plasmid].
Author: Zheng, S|Qiao, H|Lu, G
PMID: 11776569
Journal: Cancer. 2000 Apr 15;88(8):1801-6.
Title: Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives.
Author: Yu, J|Miehlke, S|Ebert, M P|Hoffmann, J|Breidert, M|Alpen, B|Starzynska, T|Stolte Prof, M|Malfertheiner, P|Bayerdorffer, E
PMID: 10760755
Journal: Oncology. 2000 Aug;59(2):145-51.
Title: High frequency of c-Met expression in gastric cancers producing alpha- fetoprotein.
Author: Amemiya, H|Kono, K|Mori, Y|Takahashi, A|Ichihara, F|Iizuka, H|Sekikawa, T|Matsumoto, Y
PMID: 10971174
Journal: Pathol Int. 2000 Oct;50(10):767-77.
Title: Molecular characteristics of eight gastric cancer cell lines established in Japan.
Author: Yokozaki, H
PMID: 11107048
Journal: Oncogene. 2000 Nov 20;19(49):5680-9.
Title: Tyrosine kinases and gastric cancer.
Author: Lin, W|Kao, H W|Robinson, D|Kung, H J|Wu, C W|Chen, H C
PMID: 11114748
Journal: Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):409-11.
Title: [The prognostic significance of expression of c-met oncogene and its relation to gastric mucosal lesions].
Author: Zhuang, X|Zheng, J|Lin, S|Sun, G|Li, Y
PMID: 11866940
Journal: Int Rev Cytol. 2001;204:49-95.
Title: Genetic and epigenetic changes in stomach cancer.
Author: Yokozaki, H|Yasui, W|Tahara, E
PMID: 11243597
Journal: Cancer. 2001 Mar 15;91(6):1156-65.
Title: Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition.
Author: Osada, S|Saji, S|Osada, K
PMID: 11267961
Journal: J Pathol. 2001 Aug;194(4):428-35.
Title: Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.
Author: Heideman, D A|Snijders, P J|Bloemena, E|Meijer, C J|Offerhaus, G J|Meuwissen, S G|Gerritsen, W R|Craanen, M E
PMID: 11523050
Journal: Med Hypotheses. 2001 Oct;57(4):503-5.
Title: Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression.
Author: Chen, J H|Liu, T Y|Wu, C W|Chi, C W
PMID: 11601879
Journal: Acta Oncol. 2001;40(5):638-43.
Title: Overexpression of the c-met protooncogene in human gastric carcinoma--correlation to clinical features.
Author: Huang, T J|Wang, J Y|Lin, S R|Lian, S T|Hsieh, J S
PMID: 11669338
Journal: Hepatogastroenterology. 2001 Nov-Dec;48(42):1788-92.
Title: Expression of insulin-like growth factor-2, c-MET, matrix metalloproteinase-7 and MUC-1 in primary lesions and lymph node metastatic lesions of gastric cancer.
Author: Ajisaka, H|Fushida, S|Yonemura, Y|Miwa, K
PMID: 11813625
Journal: Int Surg. 2001 Jul-Sep;86(3):151-7.
Title: Influence of hepatocyte growth factor secreted from fibroblasts on the growth and invasion of scirrhous gastric cancer.
Author: Murakami, N|Koufuji, K|Shirouzu, K
PMID: 11996071
Journal: Aliment Pharmacol Ther. 2002 Apr;16 Suppl 2:137-44.
Title: Detection of cancer cells in peripheral blood of stomach cancer patients using RT-PCR amplification of tumour-specific mRNAs.
Author: Shin, J-H|Chung, J|Kim, H-O|Kim, Y-H|Hur, Y-M|Rhim, J-H|Chung, H-K|Park, S-C|Park, J-G|Yang, H-K
PMID: 11966534
Journal: Oncology. 2002;63(3):286-96.
Title: c-Met expression in gastric cancer with liver metastasis.
Author: Amemiya, Hideki|Kono, Koji|Itakura, Jun|Tang, Rui Feng|Takahashi, Akihiro|An, Feng-Qi|Kamei, Shigeo|Iizuka, Hidehiko|Fujii, Hideki|Matsumoto, Yoshiro
PMID: 12381909
Journal: Arq Gastroenterol. 2002 Oct-Dec;39(4):253-9. Epub 2003 Jul 16.
Title: [Genetics and environmental factors in gastric carcinogenesis].
Author: Cesar, Ana Cristina Gobbo|Silva, Ana Elizabete|Tajara, Eloiza Helena
PMID: 12870086
Journal: J Clin Gastroenterol. 2003 Jan;36(1):30-3.
Title: Clinicopathologic characteristics and prognoses of gastric cancer in patients with a positive familial history of cancer.
Author: Lee, Wei-Jei|Hong, Rey-Long|Lai, I-Ru|Chen, Chaung-Nien|Lee, Po-Huang|Huang, Ming-Tegh
PMID: 12488704
Journal: Cancer Res. 2003 Nov 1;63(21):7345-55.
Title: A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Author: Christensen, James G|Schreck, Randall|Burrows, Jon|Kuruganti, Poonam|Chan, Emily|Le, Phuong|Chen, Jeffrey|Wang, Xueyan|Ruslim, Lany|Blake, Robert|Lipson, Kenneth E|Ramphal, John|Do, Steven|Cui, Jingrong J|Cherrington, Julie M|Mendel, Dirk B
PMID: 14612533
Journal: Cancer Res Treat. 2003 Feb;35(1):9-15.
Title: Overexpression of c-met Protein in Gastric Cancer and Role of uPAR as a Therapeutic Target.
Author: Oh, Hyun A|Lee, Gu|Kang, Hee Jung|Kim, Yong Gil|Bae, Sung Hwa|Lee, Jae Lyun|Lee, Kyung Hee|Hyun, Myung Soo|Kim, Dong Suk
PMID: 26680909
Journal: Oncol Rep. 2004 Feb;11(2):333-9.
Title: Overexpression of gastrin and c-met protein involved in human gastric carcinomas and intestinal metaplasia.
Author: Tang, Zhuobin|Zhao, Min|Ji, Jiafu|Yang, Guibin|Hu, Fulian|He, Jingsheng|Shen, Hui|Gao, Zhian|Zhao, Ailian|Li, Jiyou|Lu, Youyong
PMID: 14719064
Journal: Surg Today. 2004;34(2):115-22.
Title: c-Met expression in a gastric cancer cell line producing alpha-fetoprotein.
Author: Amemiya, Hideki|Kono, Koji|Takahashi, Akihiro|Kamei, Shigeo|Sugai, Hidemitsu|Ichihara, Fumiko|Fujii, Hideki|Matsumoto, Yoshiro
PMID: 14745610
Journal: J Gene Med. 2004 Mar;6(3):317-27.
Title: Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.
Author: Heideman, Danielle A M|van Beusechem, Victor W|Bloemena, Elisabeth|Snijders, Peter J F|Craanen, Mikael E|Offerhaus, G Johan A|Derksen, Patrick W B|de Bruin, Michiel|Witlox, M Adhiambo|Molenaar, Bonnie|Meijer, Chris J L M|Gerritsen, Winald R
PMID: 15026993
Journal: J Surg Res. 2004 Aug;120(2):242-8.
Title: Alterations of APC, c-met, and p53 genes in tumor tissue and serum of patients with gastric cancers.
Author: Wang, Jaw-Yuan|Hsieh, Jan-Sing|Chen, Chung-Chi|Tzou, Wen-Shyong|Cheng, Tien-Lu|Chen, Fang-Ming|Huang, Tsung-Jen|Huang, Yu-Sheng|Huang, Sung-Yu|Yang, Tzufeng|Lin, Shiu-Ru
PMID: 15234219
Journal: Zhonghua Yi Xue Za Zhi. 2004 Jun 17;84(12):974-8.
Title: [Increased expression of heparanase mRNA is correlated with metastasis of gastric carcinoma and is probably correlated with c-met protein].
Author: Cai, Yong-guo|Fang, Dian-chun|Yang, Shi-ming|Luo, Yuan-hui|Yang, Meng-hua|Wang, Dong-xu
PMID: 15312528
Journal: Eur J Cancer. 2004 Sep;40(14):2135-42.
Title: Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
Author: Ueda, Kentaro|Iwahashi, Makoto|Matsuura, Ichiro|Nakamori, Mikihito|Nakamura, Masaki|Ojima, Toshiyasu|Naka, Teiji|Ishida, Koichiro|Matsumoto, Kunio|Nakamura, Toshikazu|Yamaue, Hiroki
PMID: 15341989
Journal: Cancer Sci. 2004 Oct;95(10):803-8.
Title: Activation of c-Met (hepatocyte growth factor receptor) in human gastric cancer tissue.
Author: Inoue, Takao|Kataoka, Hiroaki|Goto, Kouichiro|Nagaike, Koki|Igami, Ko|Naka, Daiji|Kitamura, Naomi|Miyazawa, Keiji
PMID: 15504247
Journal: Cancer Res. 2004 Nov 1;64(21):7962-70.
Title: RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival.
Author: Shinomiya, Nariyoshi|Gao, Chong Feng|Xie, Qian|Gustafson, Margaret|Waters, David J|Zhang, Yu-Wen|Vande Woude, George F
PMID: 15520203
Journal: Exp Cell Res. 2004 Dec 10;301(2):168-78.
Title: Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.
Author: Shida, Dai|Kitayama, Joji|Yamaguchi, Hironori|Hama, Kotaro|Aoki, Junken|Arai, Hiroyuki|Yamashita, Hiroharu|Mori, Ken|Sako, Akihiro|Konishi, Tsuyoshi|Watanabe, Toshiaki|Sakai, Teruyuki|Suzuki, Rika|Ohta, Hideo|Takuwa, Yoh|Nagawa, Hirokazu
PMID: 15530853
Journal: FEBS Lett. 2004 Nov 19;577(3):333-8.
Title: Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.
Author: Shida, Dai|Kitayama, Joji|Yamaguchi, Hironori|Yamashita, Hiroharu|Mori, Ken|Watanabe, Toshiaki|Yatomi, Yutaka|Nagawa, Hirokazu
PMID: 15556605
Journal: J Med Chem. 2005 Mar 10;48(5):1359-66.
Title: Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.
Author: Kubo, Kazuo|Shimizu, Toshiyuki|Ohyama, Shin-ichi|Murooka, Hideko|Iwai, Akemi|Nakamura, Kazuhide|Hasegawa, Kazumasa|Kobayashi, Yoshiko|Takahashi, Noriko|Takahashi, Kazumi|Kato, Shinichiro|Izawa, Toshio|Isoe, Toshiyuki
PMID: 15743179
Journal: Histopathology. 2005 May;46(5):505-14.
Title: Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach.
Author: Sun, Y|Li, J-Y|He, J-S|Zhou, L-X|Chen, K
PMID: 15842632
Journal: Ann Surg. 2005 Nov;242(5):676-83.
Title: Modulation of E-cadherin by hepatocyte growth factor induces aggressiveness of gastric carcinoma.
Author: Han, Sang-Uk|Lee, Hwa-Young|Lee, Jae-Ho|Kim, Wook-Hwan|Nam, Hyunja|Kim, Hong|Cho, Yong-Kwan|Kim, Myung-Wook|Lee, Kuhn Uk
PMID: 16244541
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2005 Nov;8(6):528-30.
Title: [Effect of proto-oncogene protein c-met ribozyme transfection on biological behavior of gastric carcinoma cells].
Author: Qin, Rong|He, Zhen-ping
PMID: 16299658
Journal: Cancer Lett. 2006 Aug 8;239(2):263-70. Epub 2005 Oct 21.
Title: Effects of COX-2 inhibitor on growth of human gastric cancer cells and its relation to hepatocyte growth factor.
Author: Chen, Jen-Hao|Wu, Chew-Wun|Kao, Hwa-Li|Chang, Hwey-May|Li, Anna F-Y|Liu, Tsung-Yun|Chi, Chin-Wen
PMID: 16243430
Journal: J Surg Oncol. 2006 Jan 1;93(1):30-5.
Title: Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer.
Author: Yamashita, Hiroharu|Kitayama, Joji|Shida, Dai|Ishikawa, Makoto|Hama, Kotaro|Aoki, Junken|Arai, Hiroyuki|Nagawa, Hirokazu
PMID: 16353194
Journal: Clin Chim Acta. 2006 May;367(1-2):55-61. Epub 2006 Jan 5.
Title: Clinical significance of MUC1 and c-Met RT-PCR detection of circulating tumor cells in patients with gastric carcinoma.
Author: Uen, Yih-Huei|Lin, Shiu-Ru|Wu, Chan-Han|Hsieh, Jan-Sing|Lu, Chien-Yu|Yu, Fang-Jung|Huang, Tsung-Jen|Wang, Jaw-Yuan
PMID: 16403482
Journal: Exp Mol Med. 2006 Feb 28;38(1):27-35.
Title: Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines.
Author: Lee, Kyung Hee|Choi, Eun Young|Kim, Min Kyoung|Hyun, Myung Soo|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong
PMID: 16520550
Journal: World J Gastroenterol. 2006 Mar 28;12(12):1842-8.
Title: Correlation of Epstein-Barr virus and its encoded proteins with Helicobacter pylori and expression of c-met and c-myc in gastric carcinoma.
Author: Luo, Bing|Wang, Yun|Wang, Xiao-Feng|Gao, Yu|Huang, Bao-Hua|Zhao, Peng
PMID: 16609989
Journal: Korean J Intern Med. 2006 Mar;21(1):20-7.
Title: Hepatocyte growth factor/c-met signaling in regulating urokinase plasminogen activator in human stomach cancer: A potential therapeutic target for human stomach cancer.
Author: Lee, Kyung Hee|Choi, Eun Young|Hyun, Myung Soo|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong
PMID: 16646560
Journal: Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3541-8.
Title: TC1(C8orf4) correlates with Wnt/beta-catenin target genes and aggressive biological behavior in gastric cancer.
Author: Kim, Byungsik|Koo, Hyunlyoung|Yang, Seunghee|Bang, Seunghyun|Jung, Yusun|Kim, Youngmi|Kim, Jungtae|Park, Juhee|Moon, Randall T|Song, Kyuyoung|Lee, Inchul
PMID: 16740781
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Nov;27(11):1771-3.
Title: [Expression of hepatocyte growth factor and its receptor in gastric cancer].
Author: Chen, Jun-zhong|Zhao, Yong|Xu, Jia-feng|Liu, Qing|Liu, Sheng-huo|Zhang, Hong-de
PMID: 18024311
Journal: Mol Cancer Ther. 2007 Nov;6(11):2868-78.
Title: Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Author: Moser, Christian|Lang, Sven A|Kainz, Silvia|Gaumann, Andreas|Fichtner-Feigl, Stefan|Koehl, Gudrun E|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 18025273
Journal: Cancer Lett. 2008 Jul 8;265(2):258-69.
Title: c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases.
Author: Zeng, Zhao-Shi|Weiser, Martin R|Kuntz, Eleanor|Chen, Chin-Tung|Khan, Sajid A|Forslund, Ann|Nash, Garrett M|Gimbel, Mark|Yamaguchi, Yuka|Culliford, Alfred T 4th|D'Alessio, Matthew|Barany, Francis|Paty, Philip B
PMID: 18395971
Journal: Eur J Nucl Med Mol Imaging. 2008 Oct;35(10):1857-67.
Title: Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30.
Author: Perk, Lars R|Stigter-van Walsum, Marijke|Visser, Gerard W M|Kloet, Reina W|Vosjan, Maria J W D|Leemans, C Rene|Giaccone, Giuseppe|Albano, Raffaella|Comoglio, Paolo M|van Dongen, Guus A M S
PMID: 18491091
Journal: Oncol Rep. 2008 Jun;19(6):1477-83.
Title: The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation.
Author: Drebber, Uta|Baldus, Stephan E|Nolden, Britt|Grass, Guido|Bollschweiler, Elfriede|Dienes, Hans P|Holscher, Arnulf H|Monig, Stefan P
PMID: 18497953
Journal: Wei Sheng Yan Jiu. 2008 Jul;37(4):479-82.
Title: [Study of gastric carcinoma and PCNA and c-met gene abnormality].
Author: Ji, Jing|Zhao, Peng|Huang, Baohua
PMID: 18839537
Journal: J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66.
Title: Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
Author: Arkenau, Hendrik-Tobias
PMID: 19363621
Journal: Histol Histopathol. 2010 Jan;25(1):63-72.
Title: Expression of Reg IV and Hath1 in neuroendocrine neoplasms.
Author: Heiskala, Kukka|Arola, Johanna|Heiskala, Marja|Andersson, Leif C
PMID: 19924642
Journal: Cancer Immunol Immunother. 2010 Jun;59(6):841-50.
Title: Circulating tumour-derived microvesicles in plasma of gastric cancer patients.
Author: Baran, Jaroslaw|Baj-Krzyworzeka, Monika|Weglarczyk, Kazimierz|Szatanek, Rafal|Zembala, Maria|Barbasz, Jakub|Czupryna, Antoni|Szczepanik, Antoni|Zembala, Marek
PMID: 20043223
Journal: Cancer Chemother Pharmacol. 2010 May;65(6):1009-21.
Title: A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer.
Author: Bamias, Aristotelis|Karina, M|Papakostas, P|Kostopoulos, I|Bobos, M|Vourli, G|Samantas, E|Christodoulou, Ch|Pentheroudakis, G|Pectasides, D|Dimopoulos, M A|Fountzilas, G
PMID: 20130877
Journal: Cancer Res. 2010 Feb 15;70(4):1524-33.
Title: MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Author: Pan, Bo-Sheng|Chan, Grace K Y|Chenard, Melissa|Chi, An|Davis, Lenora J|Deshmukh, Sujal V|Gibbs, Jackson B|Gil, Susana|Hang, Gaozhen|Hatch, Harold|Jewell, James P|Kariv, Ilona|Katz, Jason D|Kunii, Kaiko|Lu, Wei|Lutterbach, Bart A|Paweletz, Cloud P|Qu, Xian
PMID: 20145145
Journal: Biochem Biophys Res Commun. 2010 Apr 16;394(4):1042-6.
Title: Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion.
Author: Asaoka, Yoshinari|Tada, Motohisa|Ikenoue, Tsuneo|Seto, Motoko|Imai, Mitsuho|Miyabayashi, Koji|Yamamoto, Keisuke|Yamamoto, Shinzo|Kudo, Yotaro|Mohri, Dai|Isomura, Yoshihiro|Ijichi, Hideaki|Tateishi, Keisuke|Kanai, Fumihiko|Ogawa, Seishi|Omata, Masao|Koike,
PMID: 20331976
Journal: Invest Clin. 2010 Sep;51(3):369-80.
Title: [Role of the expression of c-Met receptor in the progression of gastric cancer].
Author: Amemiya, Hideki|Menolascino, Francisco|Pena, Alix
PMID: 21305773
Journal: Mol Carcinog. 2011 Oct;50(10):739-50.
Title: Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules.
Author: Shan, Yan-Shen|Fang, Jung-Hua|Lai, Ming-Derg|Yen, Meng-Chi|Lin, Pin-Wen|Hsu, Hui-Ping|Lin, Chian-Yuh|Chen, Yi-Ling
PMID: 20737421
Journal: PLoS One. 2011 Jan 21;6(1):e15932.
Title: Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assay.
Author: Dua, Rajiv|Zhang, Jianhuan|Parry, Gordon|Penuel, Elicia
PMID: 21283737
Journal: Expert Opin Investig Drugs. 2011 May;20(5):595-604.
Title: New targeted therapies for gastric cancer.
Author: Asaoka, Yoshinari|Ikenoue, Tsuneo|Koike, Kazuhiko
PMID: 21406037
Journal: Oncol Rep. 2011 Jun;25(6):1517-24.
Title: Impact of MET amplification on gastric cancer: possible roles as a novel prognostic marker and a potential therapeutic target.
Author: Lee, Jeeyun|Seo, Jin Won|Jun, Hyun Jung|Ki, Chang-Seok|Park, Se Hoon|Park, Young Suk|Lim, Ho Yeong|Choi, Min Gew|Bae, Jae Moon|Sohn, Tae Sung|Noh, Jae Hyung|Kim, Sung|Jang, Hey-Lim|Kim, Ji-Youn|Kim, Kyoung-Mee|Kang, Won Ki|Park, Joon Oh
PMID: 21424128
Journal: J Exp Clin Cancer Res. 2011 Jul 7;30:67.
Title: Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells.
Author: Wei, Xu|Juan, Zhu Xiao|Min, Feng Xiao|Nan, Cai|Hua, Zhang Xiu|Qing, Feng Zheng|Zheng, Liu
PMID: 21733192
Journal: Histol Histopathol. 2011 Sep;26(9):1111-20.
Title: Up-regulated expression of Ezrin and c-Met proteins are related to the metastasis and prognosis of gastric carcinomas.
Author: Zhao, Jing|Zhang, Xiaoxiao|Xin, Yan
PMID: 21751142
Journal: J Proteome Res. 2011 Nov 4;10(11):5084-94.
Title: Discovery of a novel B-Raf fusion protein related to c-Met drug resistance.
Author: Dillon, Roslyn|Nilsson, Carol L|Shi, Stone D-H|Lee, Nathan V|Krastins, Bryan|Greig, Michael J
PMID: 21936566
Journal: Bioorg Med Chem Lett. 2011 Dec 1;21(23):7185-8.
Title: Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors.
Author: Ryu, Jae Wook|Han, Sun-Young|Yun, Jeong In|Choi, Sang-Un|Jung, Heejung|Ha, Jae Du|Cho, Sung Yun|Lee, Chong Ock|Kang, Nam Sook|Koh, Jong Sung|Kim, Hyoung Rae|Lee, Jongkook
PMID: 22001029
Journal: Chin J Cancer Res. 2011 Jun;23(2):153-9.
Title: Over-expression of Metastasis-associated in Colon Cancer-1 (MACC1) Associates with Better Prognosis of Gastric Cancer Patients.
Author: Ge, Shao-Hua|Wu, Xiao-Jiang|Wang, Xiao-Hong|Xing, Xiao-Fang|Zhang, Lian-Hai|Zhu, Yu-Bing|Du, Hong|Dong, Bin|Hu, Ying|Ji, Jia-Fu
PMID: 23483020
Journal: J Gastroenterol Hepatol. 2012 Feb;27(2):378-84.
Title: Identification of protein expression signatures in gastric carcinomas using clustering analysis.
Author: Begnami, Maria D|Fregnani, Jose Humberto T G|Brentani, Helena|Torres, Cesar|Costa, Wilson Luiz Jr|Montagnini, Andre|Nonogaki, Suely|Soares, Fernando A
PMID: 21777278
Journal: Int J Cancer. 2012 Jun 15;130(12):2912-21.
Title: Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer.
Author: Toiyama, Yuji|Yasuda, Hiromi|Saigusa, Susumu|Matushita, Kouhei|Fujikawa, Hiroyuki|Tanaka, Koji|Mohri, Yasuhiko|Inoue, Yasuhiro|Goel, Ajay|Kusunoki, Masato
PMID: 21796631
Journal: J Surg Oncol. 2012 Sep 1;106(3):304-10.
Title: Abnormal expression of E-cadherin in tumor cells is associated with poor prognosis of gastric carcinoma.
Author: Li, Yin|Chen, Chuang-Qi|He, Yu-Long|Cai, Shi-Rong|Yang, Dong-Jie|He, Wei-Ling|Xu, Jian-Bo|Zan, Wen-Hua
PMID: 22231933
Journal: Mol Cancer Ther. 2012 Mar;11(3):730-9.
Title: The novel oral Hsp90 inhibitor NVP-HSP990 exhibits potent and broad-spectrum antitumor activities in vitro and in vivo.
Author: Menezes, Daniel L|Taverna, Pietro|Jensen, Michael R|Abrams, Tinya|Stuart, Darrin|Yu, Guoying Karen|Duhl, David|Machajewski, Timothy|Sellers, William R|Pryer, Nancy K|Gao, Zhenhai
PMID: 22246440
Journal: Cancer Lett. 2012 Jun 1;319(1):109-17.
Title: c-Met upregulates aquaporin 3 expression in human gastric carcinoma cells via the ERK signalling pathway.
Author: Wang, Jianping|Gui, Zhifu|Deng, Longying|Sun, Maocai|Guo, Renhua|Zhang, Weiming|Shen, Lizong
PMID: 22261330
Journal: Acta Pharmacol Sin. 2012 Apr;33(4):513-22.
Title: Lentivirus-mediated RNA silencing of c-Met markedly suppresses peritoneal dissemination of gastric cancer in vitro and in vivo.
Author: Wang, Xiao-lei|Chen, Xi-mei|Fang, Jian-ping|Yang, Chang-qin
PMID: 22407230
Journal: Int J Mol Sci. 2012;13(4):4714-26.
Title: Frequent gene amplification predicts poor prognosis in gastric cancer.
Author: Shi, Jing|Yao, Demao|Liu, Wei|Wang, Na|Lv, Hongjun|He, Nongyue|Shi, Bingyin|Hou, Peng|Ji, Meiju
PMID: 22606006
Journal: Diagn Pathol. 2012 May 28;7:57.
Title: The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays.
Author: Sotoudeh, Kambiz|Hashemi, Forough|Madjd, Zahra|Sadeghipour, Alireza|Molanaei, Saadat|Kalantary, Elham
PMID: 22640970
Journal: PLoS One. 2012;7(6):e39653.
Title: A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation.
Author: Lee, Nathan V|Lira, Maruja E|Pavlicek, Adam|Ye, Jingjing|Buckman, Dana|Bagrodia, Shubha|Srinivasa, Sreesha P|Zhao, Yongjun|Aparicio, Samuel|Rejto, Paul A|Christensen, James G|Ching, Keith A
PMID: 22745804
Journal: Biologics. 2012;6:137-46.
Title: Metastatic gastric cancer - focus on targeted therapies.
Author: Meza-Junco, Judith|Sawyer, Michael B
PMID: 22807624
Journal: J Nucl Med. 2012 Oct;53(10):1592-600.
Title: Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab.
Author: Jagoda, Elaine M|Lang, Lixin|Bhadrasetty, Veerendra|Histed, Stephanie|Williams, Mark|Kramer-Marek, Gabriela|Mena, Esther|Rosenblum, Lauren|Marik, Jan|Tinianow, Jeff N|Merchant, Mark|Szajek, Lawrence|Paik, Chang|Cecchi, Fabiola|Raffensperger, Kristen|Jose-
PMID: 22917884
Journal: Mol Cells. 2012 Dec;34(6):523-9.
Title: A new anti-c-Met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer.
Author: Oh, Young Mi|Song, Yun-Jeong|Lee, Saet Byoul|Jeong, Yunju|Kim, Bogyou|Kim, Geun Woong|Kim, Kyung Eun|Lee, Ji Min|Cho, Mi-Young|Choi, Jaehyun|Nam, Do-Hyun|Song, Paul H|Cheong, Kwang Ho|Kim, Kyung-Ah
PMID: 23180291
Journal: Mol Imaging Biol. 2013 Apr;15(2):203-11.
Title: Preclinical evaluation of a novel c-Met inhibitor in a gastric cancer xenograft model using small animal PET.
Author: Wiehr, Stefan|von Ahsen, Oliver|Rose, Lars|Mueller, Andre|Mannheim, Julia G|Honndorf, Valerie|Kukuk, Damaris|Reischl, Gerald|Pichler, Bernd J
PMID: 22864665
Journal: Int J Cancer. 2013 May 1;132(9):2148-56.
Title: Soluble c-Met protein as a susceptible biomarker for gastric cancer risk: A nested case-control study within the Korean Multicenter Cancer Cohort.
Author: Yang, Jae Jeong|Yang, Ji Hyun|Kim, Jungkon|Ma, Seung Hyun|Cho, Lisa Y|Ko, Kwang-Pil|Shin, Aesun|Choi, Bo Youl|Kim, Hyun Ja|Han, Dong Soo|Eun, Chang Soo|Song, Kyu Sang|Kim, Yong Sung|Chang, Soung-Hoon|Shin, Hai-Rim|Kang, Daehee|Yoo, Keun-Young|Park, Sue K
PMID: 23001699
Journal: Biochem Biophys Res Commun. 2013 Feb 8;431(2):264-9.
Title: Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.
Author: Humbert, Magali|Medova, Michaela|Aebersold, Daniel M|Blaukat, Andree|Bladt, Friedhelm|Fey, Martin F|Zimmer, Yitzhak|Tschan, Mario P
PMID: 23313490
Journal: Cancer Lett. 2013 May 10;332(1):74-82.
Title: KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.
Author: Hong, Sang-Won|Jung, Kyung-Hee|Park, Byung Hee|Zheng, Hong-Mei|Lee, Hee-Seung|Choi, Myung-Joo|Yun, Jeong In|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun
PMID: 23348694
Journal: Dig Dis Sci. 2013 Jul;58(7):2038-45.
Title: MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer.
Author: Dong, Wenjie|Wang, Liping|Shen, Ruizhe
PMID: 23456500
Journal: PLoS One. 2013;8(3):e54014.
Title: Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer.
Author: Shah, Manish A|Wainberg, Zev A|Catenacci, Daniel V T|Hochster, Howard S|Ford, James|Kunz, Pamela|Lee, Fa-Chyi|Kallender, Howard|Cecchi, Fabiola|Rabe, Daniel C|Keer, Harold|Martin, Anne-Marie|Liu, Yuan|Gagnon, Robert|Bonate, Peter|Liu, Li|Gilmer, Tona|Bott
PMID: 23516391
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Mar;16(3):276-80.
Title: [Clinical study of the predictors to neoadjuvant chemotherapy in patients with advanced gastric cancer].
Author: Qu, Jian-jun|Shi, Yi-ran|Hao, Feng-yun
PMID: 23536352
Journal: Mol Cancer Ther. 2013 Jun;12(6):913-24.
Title: A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.
Author: Awazu, Yoshiko|Nakamura, Kazuhide|Mizutani, Akio|Kakoi, Yuichi|Iwata, Hidehisa|Yamasaki, Seiji|Miyamoto, Naoki|Imamura, Shinichi|Miki, Hiroshi|Hori, Akira
PMID: 23548264
Journal: Korean J Gastroenterol. 2013 Mar 25;61(3):117-27.
Title: [Perspectives of the stomach cancer treatment: the introduction of molecular targeted therapy and the hope for cure].
Author: Cheung, Dae Young|Kim, Jae Kwang
PMID: 23575230
Journal: Small. 2013 Nov 25;9(22):3834-44.
Title: Cell surface receptor targeted biomimetic apatite nanocrystals for cancer therapy.
Author: Iafisco, Michele|Delgado-Lopez, Jose Manuel|Varoni, Elena Maria|Tampieri, Anna|Rimondini, Lia|Gomez-Morales, Jaime|Prat, Maria
PMID: 23606568
Journal: Carcinogenesis. 2013 Sep;34(9):2156-69.
Title: SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities.
Author: Hong, Sang-Won|Jung, Kyung Hee|Lee, Hee-Seung|Son, Mi Kwon|Yan, Hong Hua|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun
PMID: 23671132
Journal: APMIS. 2013 Oct;121(10):926-37.
Title: Protein expression status in mucosal and submucosal portions of early gastric cancers and their predictive value for lymph node metastasis.
Author: Lee, Kyoung Bun|Park, Do Joong|Choe, Gheeyoung|Kim, Hyung-Ho|Kim, Woo Ho|Lee, Hye Seung
PMID: 23758612
Journal: PLoS One. 2013 Jun 14;8(6):e66737.
Title: Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells.
Author: Gomes, Catarina|Osorio, Hugo|Pinto, Marta Teixeira|Campos, Diana|Oliveira, Maria Jose|Reis, Celso A
PMID: 23799130
Journal: Pathol Oncol Res. 2013 Oct;19(4):821-32.
Title: Prognostic value and clinical pathology of MACC-1 and c-MET expression in gastric carcinoma.
Author: Ma, Jie|Ma, Jun|Meng, Qun|Zhao, Zhong-Sheng|Xu, Wen-juan
PMID: 23812675
Journal: J Cancer Res Clin Oncol. 2013 Nov;139(11):1835-43.
Title: Tetraspanin CD151 expression associated with prognosis for patients with advanced gastric cancer.
Author: Kang, Byung Woog|Lee, Dakeun|Chung, Ho Young|Han, Jae Ho|Kim, Young-Bae
PMID: 24005419
Journal: Cancers (Basel). 2013 Jan 21;5(1):64-91.
Title: Molecular targeted agents for gastric cancer: a step forward towards personalized therapy.
Author: Cidon, Esther Una|Ellis, Sara G|Inam, Yasir|Adeleke, Sola|Zarif, Sara|Geldart, Tom
PMID: 24216699
Journal: PLoS One. 2013 Nov 4;8(11):e79137.
Title: C-Met as a prognostic marker in gastric cancer: a systematic review and meta-analysis.
Author: Yu, Shan|Yu, Yiyi|Zhao, Naiqing|Cui, Jianlan|Li, Wei|Liu, Tianshu
PMID: 24223894
Journal: Cancer Cell Int. 2013 Dec 10;13(1):121.
Title: Expression of MACC1 and c-Met in human gastric cancer and its clinical significance.
Author: Guo, Tiankang|Yang, Jingyu|Yao, Jibin|Zhang, Yongbin|Da, Mingxu|Duan, Yaoxing
PMID: 24325214
Journal: Biomark Res. 2013 Dec 11;1(1):32.
Title: The progress of targeted therapy in advanced gastric cancer.
Author: Qiu, Miao-Zhen|Xu, Rui-Hua
PMID: 24330856
Journal: Invest Clin. 2013 Sep;54(3):284-98.
Title: [Increased expression of the c-Met receptor mRNA in gastric cancer].
Author: Amemiya, Hideki|Pena, Alix|Chiurillo, Miguel|Moscoso, Jaime|Useche, Alejandro|Baffi, Raul
PMID: 24354242
Journal: Transl Oncol. 2013 Dec 1;6(6):784-93. eCollection 2013 Dec 1.
Title: CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination.
Author: Mencarelli, Andrea|Graziosi, Luigina|Renga, Barbara|Cipriani, Sabrina|D'Amore, Claudio|Francisci, Daniela|Bruno, Angela|Baldelli, Franco|Donini, Annibale|Fiorucci, Stefano
PMID: 24466382
Journal: ACS Med Chem Lett. 2013 Jul 12;4(8):806-10.
Title: Aminopyridyl/Pyrazinyl Spiro[indoline-3,4'-piperidine]-2-ones As Highly Selective and Efficacious c-Met/ALK Inhibitors.
Author: Li, Jingrong|Wu, Nan|Tian, Yuanxin|Zhang, Jiajie|Wu, Shuguang
PMID: 24900750
Journal: BMC Res Notes. 2014 Jan 6;7:6.
Title: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma.
Author: Wu, Ju-gang|Yu, Ji-wei|Wu, Hong-biao|Zheng, Lin-hai|Ni, Xiao-chun|Li, Xiao-qiang|Du, Guang-ye|Jiang, Bo-jian
PMID: 24393368
Journal: PLoS One. 2014 Jan 8;9(1):e84502.
Title: Prognostic significance of MET amplification and expression in gastric cancer: a systematic review with meta-analysis.
Author: Peng, Zhi|Zhu, Yan|Wang, Qianqian|Gao, Jing|Li, Yilin|Li, Yanyan|Ge, Sai|Shen, Lin
PMID: 24416238
Journal: Expert Rev Gastroenterol Hepatol. 2014 Jul;8(5):555-69.
Title: Recent advances and future trends in the targeted therapy of metastatic gastric cancer.
Author: Al-Batran, Salah-Eddin|Werner, Dominique
PMID: 24665840
Journal: Ann Surg Oncol. 2014 Dec;21 Suppl 4:S584-90.
Title: Prognostic impact of major receptor tyrosine kinase expression in gastric cancer.
Author: Kurokawa, Yukinori|Matsuura, Nariaki|Kawabata, Ryohei|Nishikawa, Kazuhiro|Ebisui, Chikara|Yokoyama, Yuhki|Shaker, Mohammed Nouri|Hamakawa, Takuya|Takahashi, Tsuyoshi|Takiguchi, Shuji|Mori, Masaki|Doki, Yuichiro
PMID: 24743909
Journal: World J Gastroenterol. 2014 Apr 28;20(16):4536-45.
Title: Targeting receptor tyrosine kinases in gastric cancer.
Author: Morishita, Asahiro|Gong, Jian|Masaki, Tsutomu
PMID: 24782606
Journal: Tumour Biol. 2014 Sep;35(9):9139-46.
Title: Anti-tumor activity of oridonin on SNU-5 subcutaneous xenograft model via regulation of c-Met pathway.
Author: Liu, Hua|Qian, Changlin|Shen, Zhiyong
PMID: 24916572
Journal: Helicobacter. 2014 Sep;19 Suppl 1:32-7.
Title: Gastric cancer--epidemiologic and clinical aspects.
Author: Venerito, Marino|Nardone, Gerardo|Selgrad, Michael|Rokkas, Theodoros|Malfertheiner, Peter
PMID: 25167943
Journal: Pharmacogenet Genomics. 2014 Dec;24(12):588-96.
Title: Prognostic impact of the c-MET polymorphism on the clinical outcome in locoregional gastric cancer patients.
Author: Sunakawa, Yu|Wakatsuki, Takeru|Yang, Dongyun|Zhang, Wu|Ning, Yan|Stintzing, Sebastian|Stremitzer, Stefan|Yamauchi, Shinichi|Sebio, Ana|El-khoueiry, Rita|Iqbal, Syma|Barzi, Afsaneh|Gerger, Armin|Stotz, Michael|Azuma, Mizutomo|Watanabe, Masahiko|Koizumi, Wa
PMID: 25203738
Journal: Cold Spring Harb Protoc. 2014 Oct 1;2014(10):pdb.prot082529.
Title: Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in solid tumors.
Author: Newbold, Andrea|Martin, Ben P|Cullinane, Carleen|Bots, Michael
PMID: 25275109
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Oct;17(10):1031-5.
Title: [Influence of 17AAG on proliferation and invasion of gastric cancer cell and its mechanism].
Author: Cui, Yuehong|Yu, Yiyi|Liu, Tianshu|Xie, Qian|Wu, Weizhong|Liu, Kangda
PMID: 25341914
Journal: Gastrointest Tumors. 2014 May;1(4):180-94.
Title: Gastric Cancer: New Drugs - New Strategies.
Author: Schulte, Nadin|Ebert, Matthias P|Hartel, Nicola
PMID: 26674336
Journal: Mol Oncol. 2015 Jan;9(1):323-33.
Title: Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models.
Author: Gavine, Paul R|Ren, Yongxin|Han, Lu|Lv, Jing|Fan, Shiming|Zhang, Wei|Xu, Wen|Liu, Yuan Jie|Zhang, Tianwei|Fu, Haihua|Yu, Yongjuan|Wang, Huiying|Xu, Shirlian|Zhou, Feng|Su, Xinying|Yin, XiaoLu|Xie, Liang|Wang, Linfang|Qing, Weiguo|Jiao, Longxian|Su, Weiguo
PMID: 25248999
Journal: Mol Med Rep. 2015 Mar;11(3):2269-75.
Title: Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib.
Author: Ma, Jin-An|Hu, Chunhong|Li, Wenjuan|Ren, Jing|Zou, Fangwen|Zhou, Dongai|Zou, Wen|Wei, Yajun|Zhou, Ying
PMID: 25395073
Journal: Mol Carcinog. 2015 Dec;54(12):1700-9.
Title: Essential role of Her3 in two signaling transduction patterns: Her2/Her3 and MET/Her3 in proliferation of human gastric cancer.
Author: Yun, Chen|Gang, Li|Rongmin, Gu|Xu, Wen|Xuezhi, Ming|Huanqiu, Chen
PMID: 25400108
Journal: J Natl Cancer Inst. 2014 Nov 24;107(1):364.
Title: Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer.
Author: Kobold, Sebastian|Steffen, Julius|Chaloupka, Michael|Grassmann, Simon|Henkel, Jonas|Castoldi, Raffaella|Zeng, Yi|Chmielewski, Markus|Schmollinger, Jan C|Schnurr, Max|Rothenfusser, Simon|Schendel, Dolores J|Abken, Hinrich|Sustmann, Claudio|Niederfellner, G
PMID: 25424197
Journal: Cancer Lett. 2015 Feb 1;357(1):242-253.
Title: Metastasis-associated in colon cancer-1 upregulates vascular endothelial growth factor-C/D to promote lymphangiogenesis in human gastric cancer.
Author: Sun, Li|Duan, Jiangman|Jiang, Yaqi|Wang, Lin|Huang, Na|Lin, Li|Liao, Yulin|Liao, Wangjun
PMID: 25444928
Journal: Mol Med Rep. 2015 May;11(5):3423-31.
Title: Clinical significance of hepatocyte growth factor/c-Met expression in the assessment of gastric cancer progression.
Author: Noguchi, Eiichiro|Saito, Noboru|Kobayashi, Makio|Kameoka, Shingo
PMID: 25592281
Journal: PLoS Pathog. 2015 Feb 6;11(2):e1004663.
Title: CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation.
Author: Bertaux-Skeirik, Nina|Feng, Rui|Schumacher, Michael A|Li, Jing|Mahe, Maxime M|Engevik, Amy C|Javier, Jose E|Peek, Richard M Jr|Ottemann, Karen|Orian-Rousseau, Veronique|Boivin, Gregory P|Helmrath, Michael A|Zavros, Yana
PMID: 25658601
Journal: APMIS. 2015 May;123(5):365-72.
Title: Targeted therapy in gastric cancer.
Author: Thiel, Alexandra|Ristimaki, Ari
PMID: 25706252
Journal: Cancer Lett. 2015 May 28;361(1):57-66.
Title: Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis.
Author: Hao, Ning-Bo|Tang, Bo|Wang, Guo-Zheng|Xie, Rui|Hu, Chang-Jiang|Wang, Su-Min|Wu, Yu-Yun|Liu, En|Xie, Xia|Yang, Shi-Ming
PMID: 25727320
Journal: Oncotarget. 2015 May 10;6(13):11492-506.
Title: Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2.
Author: Wang, Lin|Lin, Li|Chen, Xi|Sun, Li|Liao, Yulin|Huang, Na|Liao, Wangjun
PMID: 25895023
Journal: Expert Opin Emerg Drugs. 2015 Sep;20(3):479-93.
Title: Emerging kinase inhibitors of the treatment of gastric cancer.
Author: Vincenzi, Bruno|Imperatori, Marco|Silletta, Marianna|Marrucci, Eleonora|Santini, Daniele|Tonini, Giuseppe
PMID: 26021342
Journal: Cancer Lett. 2015 Aug 28;365(1):30-6.
Title: c-Met targeting in advanced gastric cancer: An open challenge.
Author: Marano, Luigi|Chiari, Rita|Fabozzi, Alessio|De Vita, Ferdinando|Boccardi, Virginia|Roviello, Giandomenico|Petrioli, Roberto|Marrelli, Daniele|Roviello, Franco|Patriti, Alberto
PMID: 26049023
Journal: Cell Death Dis. 2015 Jul 2;6:e1802.
Title: LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer.
Author: Liu, Y-w|Sun, M|Xia, R|Zhang, E-b|Liu, X-h|Zhang, Z-h|Xu, T-p|De, W|Liu, B-r|Wang, Z-x
PMID: 26136075
Journal: PLoS One. 2015 Jul 17;10(7):e0128751.
Title: MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway.
Author: Zheng, Zhiqiang|Yan, Dongsheng|Chen, Xiaoyan|Huang, He|Chen, Ke|Li, Guangjing|Zhou, Linglin|Zheng, Dandan|Tu, LiLi|Dong, Xiang Da
PMID: 26186594
Journal: J Biol Chem. 2015 Oct 9;290(41):24689-704.
Title: Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor x c-MET Bispecific Antibody.
Author: Jarantow, Stephen W|Bushey, Barbara S|Pardinas, Jose R|Boakye, Ken|Lacy, Eilyn R|Sanders, Renouard|Sepulveda, Manuel A|Moores, Sheri L|Chiu, Mark L
PMID: 26260789
Journal: Hum Pathol. 2015 Dec;46(12):1901-7.
Title: Heterogeneity of c-Met expression in Chinese gastric cancer patients.
Author: Zhu, Chunchao|Xu, Jia|Li, Maoran|Zhao, Gang|Cao, Hui
PMID: 26472163
Journal: PLoS One. 2015 Nov 20;10(11):e0143207.
Title: Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis.
Author: Ye, Peng|Zhang, Meizhuo|Fan, Shuqiong|Zhang, Tianwei|Fu, Haihua|Su, Xinying|Gavine, Paul R|Liu, Qiang|Yin, Xiaolu
PMID: 26587992
Journal: Proteomes. 2015 Aug 7;3(3):160-183.
Title: Complementary PTM Profiling of Drug Response in Human Gastric Carcinoma by Immunoaffinity and IMAC Methods with Total Proteome Analysis.
Author: Stokes, Matthew P|Farnsworth, Charles L|Gu, Hongbo|Jia, Xiaoying|Worsfold, Camilla R|Yang, Vicky|Ren, Jian Min|Lee, Kimberly A|Silva, Jeffrey C
PMID: 28248267
Journal: Gastric Cancer. 2016 Jan;19(1):183-91.
Title: Prognostic impact of HER2, EGFR, and c-MET status on overall survival of advanced gastric cancer patients.
Author: Fuse, Nozomu|Kuboki, Yasutoshi|Kuwata, Takeshi|Nishina, Tomohiro|Kadowaki, Shigenori|Shinozaki, Eiji|Machida, Nozomu|Yuki, Satoshi|Ooki, Akira|Kajiura, Shinya|Kimura, Tetsuo|Yamanaka, Takeharu|Shitara, Kohei|Nagatsuma, Akiko Kawano|Yoshino, Takayuki|Ochia
PMID: 25682441
Journal: Gastric Cancer. 2016 Apr;19(2):381-91.
Title: Gastrokine 1 inhibits gastrin-induced cell proliferation.
Author: Kim, Olga|Yoon, Jung Hwan|Choi, Won Suk|Ashktorab, Hassan|Smoot, Duane T|Nam, Suk Woo|Lee, Jung Young|Park, Won Sang
PMID: 25752269
Journal: Histopathology. 2016 Jan;68(2):241-53.
Title: MET in gastric cancer--discarding a 10% cutoff rule.
Author: Metzger, Marie-Luise|Behrens, Hans-Michael|Boger, Christine|Haag, Jochen|Kruger, Sandra|Rocken, Christoph
PMID: 26033401
Journal: Ann Oncol. 2016 Jan;27(1):127-33.
Title: Comprehensive analyses using next-generation sequencing and immunohistochemistry enable precise treatment in advanced gastric cancer.
Author: Kuboki, Y|Yamashita, S|Niwa, T|Ushijima, T|Nagatsuma, A|Kuwata, T|Yoshino, T|Doi, T|Ochiai, A|Ohtsu, A
PMID: 26489445
Journal: Int J Cancer. 2016 Apr 1;138(7):1680-8.
Title: Rab11-FIP2 promotes the metastasis of gastric cancer cells.
Author: Dong, Wenjie|Qin, Guohui|Shen, Ruizhe
PMID: 26502090
Journal: Stem Cells. 2016 Apr;34(4):1011-26.
Title: Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis.
Author: Berger, Liron|Shamai, Yeela|Skorecki, Karl L|Tzukerman, Maty
PMID: 26676563
Journal: J Exp Clin Cancer Res. 2016 Jan 4;35:1.
Title: Molecular targeted therapy for the treatment of gastric cancer.
Author: Xu, Wenting|Yang, Zhen|Lu, Nonghua
PMID: 26728266
Journal: Arch Pharm Res. 2016 Apr;39(4):453-64.
Title: Discovery of substituted pyrazol-4-yl pyridazinone derivatives as novel c-Met kinase inhibitors.
Author: Kim, Eun-Young|Kang, Seung-Tae|Jung, Heejung|Park, Chi Hoon|Yun, Chang-Soo|Hwang, Jong Yeon|Byun, Byung Jin|Lee, Chong Ock|Kim, Hyoung Rae|Ha, Jae Du|Ryu, Do Hyun|Cho, Sung Yun
PMID: 26753914
Journal: J Exp Clin Cancer Res. 2016 Jan 22;35:16.
Title: Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors.
Author: Li, Linhao|Jiang, Xian|Zhang, Qian|Dong, Xuesong|Gao, Yuqiang|He, Yuanlong|Qiao, Haiquan|Xie, Fangyu|Xie, Xiangjun|Sun, Xueying
PMID: 26795388
Journal: BMC Cancer. 2016 Jan 22;16:35.
Title: Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells.
Author: Park, Chi Hoon|Cho, Sung Yun|Ha, Jae Du|Jung, Heejung|Kim, Hyung Rae|Lee, Chong Ock|Jang, In-Young|Chae, Chong Hak|Lee, Heung Kyoung|Choi, Sang Un
PMID: 26801760
Journal: World J Gastroenterol. 2016 Jan 14;22(2):471-89.
Title: Targeted therapies in gastric cancer and future perspectives.
Author: Yazici, Ozan|Sendur, M Ali Nahit|Ozdemir, Nuriye|Aksoy, Sercan
PMID: 26811601
Journal: J Gastrointest Cancer. 2016 Jun;47(2):125-34.
Title: Advances of Molecular Targeted Therapy in Gastric Cancer.
Author: Cetin, Bulent|Gumusay, Ozge|Cengiz, Mustafa|Ozet, Ahmet
PMID: 26875080
Journal: BMC Cancer. 2016 Feb 16;16:105.
Title: Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
Author: Wang, Jieyi|Goetsch, Liliane|Tucker, Lora|Zhang, Qian|Gonzalez, Alexandra|Vaidya, Kedar S|Oleksijew, Anatol|Boghaert, Erwin|Song, Minghao|Sokolova, Irina|Pestova, Ekaterina|Anderson, Mark|Pappano, William N|Ansell, Peter|Bhathena, Anahita|Naumovski, Louie
PMID: 26879245
Journal: Oncol Lett. 2016 Feb;11(2):991-997.
Title: Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells.
Author: Kim, Dong Chul|Park, Kyeong Ryang|Jeong, Yeon Ji|Yoon, Hyonok|Ahn, Mi-Jeong|Rho, Gyu-Jin|Lee, Jongkook|Gong, Young-Dae|Han, Sun-Young
PMID: 26893681
Journal: Appl Immunohistochem Mol Morphol. 2016 Apr;24(4):246-52.
Title: Mesothelin Expression in Advanced Gastroesophageal Cancer Represents a Novel Target for Immunotherapy.
Author: Illei, Peter B|Alewine, Christine|Zahurak, Marianna|Cowan, Morgan L|Montgomery, Elizabeth|Hassan, Raffit|Xiang, Laiman|Pastan, Ira|Kelly, Ronan J
PMID: 26894650
Journal: Clin Cancer Res. 2016 Jul 15;22(14):3683-94.
Title: Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays.
Author: Srivastava, Apurva K|Hollingshead, Melinda G|Weiner, Jennifer|Navas, Tony|Evrard, Yvonne A|Khin, Sonny A|Ji, Jiuping Jay|Zhang, Yiping|Borgel, Suzanne|Pfister, Thomas D|Kinders, Robert J|Bottaro, Donald P|Linehan, W Marston|Tomaszewski, Joseph E|Doroshow,
PMID: 27001313
Journal: Int J Cancer. 2016 Oct 15;139(8):1851-63.
Title: A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors.
Author: Gonzalez, Alexandra|Broussas, Matthieu|Beau-Larvor, Charlotte|Haeuw, Jean-Francois|Boute, Nicolas|Robert, Alain|Champion, Thierry|Beck, Alain|Bailly, Christian|Corvaia, Nathalie|Goetsch, Liliane
PMID: 27144973
Journal: Oncotarget. 2016 Jun 7;7(23):34190-200.
Title: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.
Author: Wu, Yan|Yao, Xiaoyuan|Zhu, Miaolin|Qian, Hai|Jiang, Lu|Lan, Ting|Wu, Min|Pang, Ji|Chen, Yongchang
PMID: 27147579
Journal: Dig Liver Dis. 2016 Sep;48(9):984-94.
Title: Recent insights in the therapeutic management of patients with gastric cancer.
Author: de Mestier, Louis|Lardiere-Deguelte, Sophie|Volet, Julien|Kianmanesh, Reza|Bouche, Olivier
PMID: 27156069
Journal: Oncotarget. 2016 Jun 21;7(25):38091-38104.
Title: Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities.
Author: Wang, Ying|Zhan, Zhengsheng|Jiang, Xifei|Peng, Xia|Shen, Yanyan|Chen, Fang|Ji, Yinchun|Liu, Weiren|Shi, Yinghong|Duan, Wenhu|Ding, Jian|Ai, Jing|Geng, Meiyu
PMID: 27191264
Journal: World J Gastroenterol. 2016 May 21;22(19):4638-50.
Title: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management.
Author: Joo, Moon Kyung|Park, Jong-Jae|Chun, Hoon Jai
PMID: 27217696
Journal: World J Gastroenterol. 2016 May 28;22(20):4812-23.
Title: Current and emerging therapies in unresectable and recurrent gastric cancer.
Author: Jou, Erin|Rajdev, Lakshmi
PMID: 27239108
Journal: Asian Pac J Trop Med. 2016 May;9(5):508-12.
Title: Inhibition of long non-coding RNA TUG1 on gastric cancer cell transference and invasion through regulating and controlling the expression of miR-144/c-Met axis.
Author: Ji, Ting-Ting|Huang, Xuan|Jin, Jie|Pan, Sheng-Hua|Zhuge, Xiao-Ju
PMID: 27261864
Journal: Cancer Biomark. 2016 Jun 7;17(1):49-54.
Title: The predictors of response to neoadjuvant chemotherapy in patients with locally advanced gastric cancer.
Author: Qu, Jianjun|Qu, Xiangyang
PMID: 27314292
Journal: Int J Cancer. 2016 Dec 1;139(11):2553-69.
Title: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.
Author: Xia, Jianling|Huang, Na|Huang, Hongxiang|Sun, Li|Dong, Shaoting|Su, Jinyu|Zhang, Jingwen|Wang, Lin|Lin, Li|Shi, Min|Bin, Jianping|Liao, Yulin|Li, Nailin|Liao, Wangjun
PMID: 27529686
Journal: J Biol Chem. 2016 Sep 30;291(40):20891-20899.
Title: The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer.
Author: Watanabe, Kenta|Hirata, Michiko|Tominari, Tsukasa|Matsumoto, Chiho|Fujita, Hidenori|Yonekura, Kazuhiko|Murphy, Gillian|Nagase, Hideaki|Miyaura, Chisato|Inada, Masaki
PMID: 27539855
Journal: Tumour Biol. 2016 Nov;37(11):15175-15183.
Title: Direct targeting of HGF by miR-16 regulates proliferation and migration in gastric cancer.
Author: Li, Shuang|Zhang, Haiyang|Wang, Xinyi|Qu, Yanjun|Duan, Jingjing|Liu, Rui|Deng, Ting|Ning, Tao|Zhang, Le|Bai, Ming|Zhou, Likun|Wang, Xia|Ge, Shaohua|Ying, Guoguang|Ba, Yi
PMID: 27683052
Journal: Onco Targets Ther. 2016 Sep 22;9:5809-5817.
Title: Evaluation of c-Met, HGF, and HER-2 expressions in gastric carcinoma and their association with other clinicopathological factors.
Author: Yildiz, Yetkin|Sokmensuer, Cenk|Yalcin, Suayib
PMID: 27703380
Journal: Onco Targets Ther. 2016 Sep 27;9:5919-5929.
Title: The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study.
Author: Jia, Yong-Xu|Li, Teng-Fei|Zhang, Dan-Dan|Fan, Zong-Min|Fan, Hui-Jie|Yan, Jie|Chen, Li-Juan|Tang, Hong|Qin, Yan-Ru|Li, Xing-Ya
PMID: 27729801
Journal: J Gastric Cancer. 2016 Sep;16(3):141-151.
Title: Clinicopathological Significance and Diagnostic Accuracy of c-MET Expression by Immunohistochemistry in Gastric Cancer: A Meta-Analysis.
Author: Pyo, Jung-Soo|Kang, Guhyun|Cho, Hyunjin
PMID: 27752391
Journal: Cancer Lett. 2017 Jan 28;385:144-149.
Title: In vivo targeting of c-Met using a non-standard macrocyclic peptide in gastric carcinoma.
Author: Hwang, Do Won|Bahng, Namryeong|Ito, Kenichiro|Ha, Seunggyun|Kim, Mee Young|Lee, Eunji|Suga, Hiroaki|Lee, Dong Soo
PMID: 27810404
Journal: BMC Cancer. 2017 Mar 14;17(1):191.
Title: Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways.
Author: Wang, Haiyong|Lu, Jun|Tang, Jian|Chen, Shitu|He, Kuifeng|Jiang, Xiaoxia|Jiang, Weiqin|Teng, Lisong
PMID: 28292264
Journal: Anticancer Res. 2017 Mar;37(3):1127-1138.
Title: Increased HGF Expression Induces Resistance to c-MET Tyrosine Kinase Inhibitors in Gastric Cancer.
Author: Ahn, So Yeong|Kim, Jin|Kim, Min A|Choi, Jiwoon|Kim, Woo Ho
PMID: 28314274
Journal: Nat Commun. 2017 Apr 10;8:15016.
Title: Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis.
Author: Zhang, Haiyang|Deng, Ting|Liu, Rui|Bai, Ming|Zhou, Likun|Wang, Xia|Li, Shuang|Wang, Xinyi|Yang, Haiou|Li, Jialu|Ning, Tao|Huang, Dingzhi|Li, Hongli|Zhang, Le|Ying, Guoguang|Ba, Yi
PMID: 28393839
Journal: Oncotarget. 2017 Apr 25;8(17):29067-29079.
Title: A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer.
Author: Sun, Zu-Jun|Wu, Yi|Hou, Wei-Hua|Wang, Yu-Xiong|Yuan, Qing-Yun|Wang, Hui-Jie|Yu, Min
PMID: 28404966
Journal: Eur J Med Chem. 2017 Jul 7;134:147-158.
Title: Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization.
Author: Zhao, Fei|Zhang, Le-Duo|Hao, Yu|Chen, Na|Bai, Rui|Wang, Yu-Ji|Zhang, Chun-Chun|Li, Gong-Sheng|Hao, Li-Jun|Shi, Chen|Zhang, Jing|Mao, Yu|Fan, Yi|Xia, Guang-Xin|Yu, Jian-Xin|Liu, Yan-Jun
PMID: 28411455
Journal: Oncotarget. 2017 Jul 18;8(29):48253-48262.
Title: Efficacy and safety of different molecular targeted agents based on chemotherapy for gastric cancer patients treatment: a network meta-analysis.
Author: Ren, Zheng|Sun, Jinping|Sun, Xinfang|Hou, Hongtao|Li, Ke|Ge, Quanxing
PMID: 28477027
Journal: Bioorg Chem. 2017 Aug;73:154-169.
Title: Target identification, lead optimization and antitumor evaluation of some new 1,2,4-triazines as c-Met kinase inhibitors.
Author: El-Wakil, Marwa H|Ashour, Hayam M|Saudi, Manal N|Hassan, Ahmed M|Labouta, Ibrahim M
PMID: 28715754
Journal: J Gastrointest Oncol. 2017 Jun;8(3):418-429.
Title: Biologic therapy in esophageal and gastric malignancies: current therapies and future directions.
Author: Samson, Pamela|Lockhart, A Craig
PMID: 28736629
Journal: Oncotarget. 2017 Apr 29;8(32):52584-52593.
Title: siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells.
Author: Yuan, Heng-Heng|Yang, Ying-Nan|Zhou, Jian-Hua|Li, Yan-Jing|Wang, Li-Ying|Qin, Jun-Wei|Liu, Tao|Li, Zhen-Zhen|Zhou, Qing-Xin|Wei, Xiao-Li|Zhang, Ting-Ting|Huang, Peng|Zhang, Wen-Jie|Liu, Lei|Du, Xiao-Xue|Han, Yu
PMID: 28881753
Journal: Biochimie. 2017 Nov;142:135-143.
Title: Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas.
Author: Mihailidou, Chrysovalantou|Karamouzis, Michalis V|Schizas, Dimitrios|Papavassiliou, Athanasios G
PMID: 28890386
Journal: Chonnam Med J. 2017 Sep;53(3):178-186.
Title: Role of Recepteur D'origine Nantais on Gastric Cancer Development and Progression.
Author: Yang, Sung Yeul|Nguyen, Thi Thinh|Ung, Trong Thuan|Jung, Young Do
PMID: 29026705
Journal: Biomed Res Int. 2017;2017:7869802.
Title: Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer.
Author: Carlomagno, Nicola|Incollingo, Paola|Tammaro, Vincenzo|Peluso, Gaia|Rupealta, Niccolo|Chiacchio, Gaetano|Sandoval Sotelo, Maria Laura|Minieri, Gianluca|Pisani, Antonio|Riccio, Eleonora|Sabbatini, Massimo|Bracale, Umberto Marcello|Calogero, Armando|Dodaro,
PMID: 29094049
Journal: Oncotarget. 2017 Nov 11;8(62):105727-105734.
Title: MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines.
Author: Kim, Jung Eun|Kim, Youjin|Li, Gary|Kim, Seung Tae|Kim, Kyung|Park, Se Hoon|Park, Joon Oh|Park, Young Suk|Lim, Ho Yeong|Lee, Hyuk|Sohn, Tae Sung|Kim, Kyoung-Mee|Kang, Won Ki|Lee, Jeeyun
PMID: 29285287
Journal: Oncotarget. 2017 Dec 6;9(2):1641-1655.
Title: Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors.
Author: Ohashi, Yoshimi|Okamura, Mutsumi|Katayama, Ryohei|Fang, Siyang|Tsutsui, Saki|Akatsuka, Akinobu|Shan, Mingde|Choi, Hyeong-Wook|Fujita, Naoya|Yoshimatsu, Kentaro|Shiina, Isamu|Yamori, Takao|Dan, Shingo
PMID: 29416720
Journal: Oncol Lett. 2018 Jan;15(1):947-955.
Title: Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis.
Author: Huang, Xiaojun|Wang, Chaoqun|Sun, Jinmin|Luo, Jun|You, Jiangzhou|Liao, Linchuan|Li, Mingyuan
PMID: 29422968
Journal: Oncol Lett. 2018 Mar;15(3):3207-3213.
Title: MACC1 and HGF are associated with survival in patients with gastric cancer.
Author: Dong, Guokai|Wang, Man|Gu, Guangfu|Li, Shanshan|Sun, Xiaoming|Li, Zhouru|Cai, Hongxing|Zhu, Zhengqiu
PMID: 29435059
Journal: Transl Oncol. 2018 Apr;11(2):487-497.
Title: The Chemokine Receptor CXCR4 and c-MET Cooperatively Promote Epithelial-Mesenchymal Transition in Gastric Cancer Cells.
Author: Cheng, Yu|Song, Yongxi|Qu, Jinglei|Che, Xiaofang|Song, Na|Fan, Yibo|Wen, Ti|Xu, Ling|Gong, Jing|Wang, Xiaoxun|Zhang, Chenlu|Qu, Xiujuan|Liu, Yunpeng
PMID: 29494948
Journal: Oncol Rep. 2018 Jul;40(1):294-302.
Title: Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells.
Author: Huang, Kuo-Hung|Sung, I-Cheng|Fang, Wen-Liang|Chi, Chin-Wen|Yeh, Tien-Shun|Lee, Hsin-Chen|Yin, Pen-Hui|Li, Anna Fen-Yau|Wu, Chew-Wun|Shyr, Yi-Ming|Yang, Muh-Hwa
PMID: 29781036
Journal: Gastric Cancer. 2018 Jun 27. pii: 10.1007/s10120-018-0853-7.
Title: Human epidermal growth factor receptor 2-, epidermal growth factor receptor-, and mesenchymal epithelial transition factor-positive sites of gastric cancer using surgical samples.
Author: Oono, Yasuhiro|Kuwata, Takeshi|Takashima, Kenji|Shinmura, Kensuke|Hori, Keisuke|Yoda, Yusuke|Ikematsu, Hiroaki|Shitara, Kohei|Kinoshita, Takahiro|Yano, Tomonori
PMID: 29951752
Journal: Biomol Ther (Seoul). 2018 Jul 30. pii: biomolther.2018.091.
Title: Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with in vitro Anti-Tumor Effects.
Author: Ndolo, Karyn Muzinga|An, Su Jin|Park, Kyeong Ryang|Lee, Hyo Jeong|Yoon, Kyoung Bin|Kim, Yong-Chul|Han, Sun-Young
PMID: 30060294
Journal: Ann Transl Med. 2018 Jun;6(12):247.
Title: Current advances of targeting HGF/c-Met pathway in gastric cancer.
Author: Anestis, Aristomenis|Zoi, Ilianna|Karamouzis, Michalis V
PMID: 30069449
Journal: Cell Death Dis. 2018 Aug 29;9(9):867.
Title: HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis.
Author: Ding, Xusheng|Ji, Jun|Jiang, Jinling|Cai, Qu|Wang, Chao|Shi, Min|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 30158543
Journal: Oncol Lett. 2018 Oct;16(4):4271-4278.
Title: Human chorionic gonadotropin promotes cell proliferation through the activation of c-Met in gastric cancer cells.
Author: Zhao, Rui|Zhang, Tongtong|Xi, Weidong|Sun, Xiaobin|Zhou, Lingxiao|Guo, Yuanbiao|Zhao, Cong|Bao, Yu
PMID: 30197669
Journal: Expert Opin Drug Saf. 2018 Nov;17(11):1145-1150.
Title: The safety of apatinib for the treatment of gastric cancer.
Author: Geng, Ruixuan|Song, Li|Li, Jin|Zhao, Lin
PMID: 30324820
Journal: In Vivo. 2018 Nov-Dec;32(6):1491-1498.
Title: Changes in HER2 Expression and Amplification Status Following Preoperative Chemotherapy for Gastric Cancer.
Author: Shu, Sei|Iimori, Makoto|Nakanishi, Ryota|Jogo, Tomoko|Saeki, Hiroshi|Oki, Eiji|Maehara, Yoshihiko
PMID: 30348707