Primary Site >> Stomach Cancer
Gene >> MET
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Biosynthesis of the protein encoded by the c-met proto-oncogene. PMID: 2554238 |
Ref: Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein. PMID: 2111905 Ref: Gene amplification in gastric and esophageal adenocarcinomas. PMID: 2400999 |
Ref: Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase. PMID: 1655790 Ref: c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase. PMID: 1674365 |
Ref: Frequent amplification of the c-met gene in scirrhous type stomach cancer. PMID: 1333188 Ref: Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene. PMID: 1486568 |
Ref: [Metastasis related genes and malignancy in human esophageal, gastric and colorectal cancers]. PMID: 8094950 Ref: Aberrant expression of c-met mRNA in human gastric carcinomas. PMID: 8344755 Ref: Molecular mechanism of stomach carcinogenesis. PMID: 8440743 Ref: GC factor represses transcription of several growth factor/receptor genes and causes growth inhibition of human gastric carcinoma cell lines. PMID: 8494791 Ref: Biologic effect of human hepatocyte growth-factor on human gastric-carcinoma cell-lines. PMID: 21573331 Ref: Expression of hepatocyte growth factor(hgf) and C-met gene in human gastric-cancer cell-lines. PMID: 21573474 |
Ref: [Metastasis-related genes]. PMID: 7526801 Ref: [Genetic characteristics of scirrhous gastric carcinomas]. PMID: 7944479 Ref: Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines. PMID: 7952499 Ref: Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas. PMID: 7960231 Ref: The Met/hepatocyte growth factor receptor (HGFR) gene is overexpressed in some cases of human leukemia and lymphoma. PMID: 8289471 Ref: Cancer-stromal interaction through growth factor/cytokine networks implicated in growth of stomach cancer. PMID: 8983075 |
Ref: Molecular biology of gastric cancer. PMID: 7676688 Ref: Roles of hepatocyte growth factor and its receptor in gastric mucosa. A cell biological and molecular biological study. PMID: 7729276 Ref: Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosis. PMID: 7889467 |
Ref: Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells. PMID: 8612619 Ref: [Genetic alterations in stomach cancer]. PMID: 8692139 Ref: [Activation of proto-oncogenes induced by MNNG on primary culture of human gastric epithelium and immortalized human gastric epithelial cell line]. PMID: 8732101 Ref: [Multistep stomach carcinogenesis]. PMID: 8920675 Ref: Participation of c-met in the progression of human gastric cancers: anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells. PMID: 8988842 Ref: [The overexpression of c-met oncogene correlation with gastric mucosal lesion]. PMID: 9206200 Ref: [Studies on the phenotype deviation of the single-cell subclones of human stomach carcinoma MGC-803 cell line]. PMID: 9208638 Ref: [Correlation of multiple gene changes with malignant phenotype of human gastric carcinoma]. PMID: 9275549 Ref: Correlation between overexpression of c-met gene and the progression of gastric cancer. PMID: 21544396 Ref: A splice variant of the c-met proto-oncogene is the predominant population expressed in human gastric mucosa and carcinoma. PMID: 21594385 |
Ref: Transforming growth factor-beta and hepatocyte growth factor produced by gastric fibroblasts stimulate the invasiveness of scirrhous gastric cancer cells. PMID: 9119743 Ref: Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection. PMID: 9136822 Ref: Effect of hepatocyte growth factor on cell cycle and c-met expression in human gastric cancer cells. PMID: 9413205 Ref: Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer. PMID: 9428926 Ref: E-cadherin and c-met expression as a prognostic factor in gastric cancer. PMID: 21590132 |
Ref: The relation between the growth patterns of gastric carcinoma and the expression of hepatocyte growth factor receptor (c-met), autocrine motility factor receptor, and urokinase-type plasminogen activator receptor. PMID: 9610690 Ref: Prostatic carcinoma with signet ring cells: a clinicopathologic and immunohistochemical analysis of 12 cases, with review of the literature. PMID: 9647593 Ref: Amplification of the c-met, c-erbB-2 and epidermal growth factor receptor gene in human gastric cancers: correlation to clinical features. PMID: 9732228 Ref: Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization. PMID: 9759658 Ref: Expression of cadherin-catenin cell adhesion molecules, phosphorylated tyrosine residues and growth factor receptor-tyrosine kinases in gastric cancers. PMID: 9765619 Ref: [New molecular prognostic markers in gastric carcinoma]. PMID: 9838902 Ref: [The relationship between Helicobacter pylori and expression of c-met oncogene in gastric precancerous lesions]. PMID: 10923453 |
Ref: The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. PMID: 10223227 Ref: PPARgamma inhibits the expression of c-MET in human gastric cancer cells through the suppression of Ets. PMID: 10558888 Ref: [Gene detection and localization by FISH with short DNA fragment cloned in plasmid]. PMID: 11776569 |
Ref: Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives. PMID: 10760755 Ref: High frequency of c-Met expression in gastric cancers producing alpha- fetoprotein. PMID: 10971174 Ref: Molecular characteristics of eight gastric cancer cell lines established in Japan. PMID: 11107048 Ref: Tyrosine kinases and gastric cancer. PMID: 11114748 Ref: [The prognostic significance of expression of c-met oncogene and its relation to gastric mucosal lesions]. PMID: 11866940 |
Ref: Genetic and epigenetic changes in stomach cancer. PMID: 11243597 Ref: Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition. PMID: 11267961 Ref: Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma. PMID: 11523050 Ref: Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression. PMID: 11601879 Ref: Overexpression of the c-met protooncogene in human gastric carcinoma--correlation to clinical features. PMID: 11669338 Ref: Expression of insulin-like growth factor-2, c-MET, matrix metalloproteinase-7 and MUC-1 in primary lesions and lymph node metastatic lesions of gastric cancer. PMID: 11813625 Ref: Influence of hepatocyte growth factor secreted from fibroblasts on the growth and invasion of scirrhous gastric cancer. PMID: 11996071 |
Ref: Detection of cancer cells in peripheral blood of stomach cancer patients using RT-PCR amplification of tumour-specific mRNAs. PMID: 11966534 Ref: c-Met expression in gastric cancer with liver metastasis. PMID: 12381909 Ref: [Genetics and environmental factors in gastric carcinogenesis]. PMID: 12870086 |
Ref: Clinicopathologic characteristics and prognoses of gastric cancer in patients with a positive familial history of cancer. PMID: 12488704 Ref: A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. PMID: 14612533 Ref: Overexpression of c-met Protein in Gastric Cancer and Role of uPAR as a Therapeutic Target. PMID: 26680909 |
Ref: Overexpression of gastrin and c-met protein involved in human gastric carcinomas and intestinal metaplasia. PMID: 14719064 Ref: c-Met expression in a gastric cancer cell line producing alpha-fetoprotein. PMID: 14745610 Ref: Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4. PMID: 15026993 Ref: Alterations of APC, c-met, and p53 genes in tumor tissue and serum of patients with gastric cancers. PMID: 15234219 Ref: [Increased expression of heparanase mRNA is correlated with metastasis of gastric carcinoma and is probably correlated with c-met protein]. PMID: 15312528 Ref: Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice. PMID: 15341989 Ref: Activation of c-Met (hepatocyte growth factor receptor) in human gastric cancer tissue. PMID: 15504247 Ref: RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival. PMID: 15520203 Ref: Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells. PMID: 15530853 Ref: Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells. PMID: 15556605 |
Ref: Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas. PMID: 15743179 Ref: Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach. PMID: 15842632 Ref: Modulation of E-cadherin by hepatocyte growth factor induces aggressiveness of gastric carcinoma. PMID: 16244541 Ref: [Effect of proto-oncogene protein c-met ribozyme transfection on biological behavior of gastric carcinoma cells]. PMID: 16299658 |
Ref: Effects of COX-2 inhibitor on growth of human gastric cancer cells and its relation to hepatocyte growth factor. PMID: 16243430 Ref: Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer. PMID: 16353194 Ref: Clinical significance of MUC1 and c-Met RT-PCR detection of circulating tumor cells in patients with gastric carcinoma. PMID: 16403482 Ref: Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines. PMID: 16520550 Ref: Correlation of Epstein-Barr virus and its encoded proteins with Helicobacter pylori and expression of c-met and c-myc in gastric carcinoma. PMID: 16609989 Ref: Hepatocyte growth factor/c-met signaling in regulating urokinase plasminogen activator in human stomach cancer: A potential therapeutic target for human stomach cancer. PMID: 16646560 Ref: TC1(C8orf4) correlates with Wnt/beta-catenin target genes and aggressive biological behavior in gastric cancer. PMID: 16740781 |
Ref: [Expression of hepatocyte growth factor and its receptor in gastric cancer]. PMID: 18024311 Ref: Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo. PMID: 18025273 |
Ref: c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases. PMID: 18395971 Ref: Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30. PMID: 18491091 Ref: The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation. PMID: 18497953 Ref: [Study of gastric carcinoma and PCNA and c-met gene abnormality]. PMID: 18839537 |
Ref: Gastric cancer in the era of molecularly targeted agents: current drug development strategies. PMID: 19363621 |
Ref: Expression of Reg IV and Hath1 in neuroendocrine neoplasms. PMID: 19924642 Ref: Circulating tumour-derived microvesicles in plasma of gastric cancer patients. PMID: 20043223 Ref: A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer. PMID: 20130877 Ref: MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. PMID: 20145145 Ref: Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion. PMID: 20331976 Ref: [Role of the expression of c-Met receptor in the progression of gastric cancer]. PMID: 21305773 |
Ref: Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules. PMID: 20737421 Ref: Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assay. PMID: 21283737 Ref: New targeted therapies for gastric cancer. PMID: 21406037 Ref: Impact of MET amplification on gastric cancer: possible roles as a novel prognostic marker and a potential therapeutic target. PMID: 21424128 Ref: Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells. PMID: 21733192 Ref: Up-regulated expression of Ezrin and c-Met proteins are related to the metastasis and prognosis of gastric carcinomas. PMID: 21751142 Ref: Discovery of a novel B-Raf fusion protein related to c-Met drug resistance. PMID: 21936566 Ref: Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors. PMID: 22001029 Ref: Over-expression of Metastasis-associated in Colon Cancer-1 (MACC1) Associates with Better Prognosis of Gastric Cancer Patients. PMID: 23483020 |
Ref: Identification of protein expression signatures in gastric carcinomas using clustering analysis. PMID: 21777278 Ref: Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer. PMID: 21796631 Ref: Abnormal expression of E-cadherin in tumor cells is associated with poor prognosis of gastric carcinoma. PMID: 22231933 Ref: The novel oral Hsp90 inhibitor NVP-HSP990 exhibits potent and broad-spectrum antitumor activities in vitro and in vivo. PMID: 22246440 Ref: c-Met upregulates aquaporin 3 expression in human gastric carcinoma cells via the ERK signalling pathway. PMID: 22261330 Ref: Lentivirus-mediated RNA silencing of c-Met markedly suppresses peritoneal dissemination of gastric cancer in vitro and in vivo. PMID: 22407230 Ref: Frequent gene amplification predicts poor prognosis in gastric cancer. PMID: 22606006 Ref: The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays. PMID: 22640970 Ref: A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation. PMID: 22745804 Ref: Metastatic gastric cancer - focus on targeted therapies. PMID: 22807624 Ref: Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab. PMID: 22917884 Ref: A new anti-c-Met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer. PMID: 23180291 |
Ref: Preclinical evaluation of a novel c-Met inhibitor in a gastric cancer xenograft model using small animal PET. PMID: 22864665 Ref: Soluble c-Met protein as a susceptible biomarker for gastric cancer risk: A nested case-control study within the Korean Multicenter Cancer Cohort. PMID: 23001699 Ref: Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells. PMID: 23313490 Ref: KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer. PMID: 23348694 Ref: MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer. PMID: 23456500 Ref: Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer. PMID: 23516391 Ref: [Clinical study of the predictors to neoadjuvant chemotherapy in patients with advanced gastric cancer]. PMID: 23536352 Ref: A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities. PMID: 23548264 Ref: [Perspectives of the stomach cancer treatment: the introduction of molecular targeted therapy and the hope for cure]. PMID: 23575230 Ref: Cell surface receptor targeted biomimetic apatite nanocrystals for cancer therapy. PMID: 23606568 Ref: SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. PMID: 23671132 Ref: Protein expression status in mucosal and submucosal portions of early gastric cancers and their predictive value for lymph node metastasis. PMID: 23758612 Ref: Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells. PMID: 23799130 Ref: Prognostic value and clinical pathology of MACC-1 and c-MET expression in gastric carcinoma. PMID: 23812675 Ref: Tetraspanin CD151 expression associated with prognosis for patients with advanced gastric cancer. PMID: 24005419 Ref: Molecular targeted agents for gastric cancer: a step forward towards personalized therapy. PMID: 24216699 Ref: C-Met as a prognostic marker in gastric cancer: a systematic review and meta-analysis. PMID: 24223894 Ref: Expression of MACC1 and c-Met in human gastric cancer and its clinical significance. PMID: 24325214 Ref: The progress of targeted therapy in advanced gastric cancer. PMID: 24330856 Ref: [Increased expression of the c-Met receptor mRNA in gastric cancer]. PMID: 24354242 Ref: CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination. PMID: 24466382 Ref: Aminopyridyl/Pyrazinyl Spiro[indoline-3,4'-piperidine]-2-ones As Highly Selective and Efficacious c-Met/ALK Inhibitors. PMID: 24900750 |
Ref: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma. PMID: 24393368 Ref: Prognostic significance of MET amplification and expression in gastric cancer: a systematic review with meta-analysis. PMID: 24416238 Ref: Recent advances and future trends in the targeted therapy of metastatic gastric cancer. PMID: 24665840 Ref: Prognostic impact of major receptor tyrosine kinase expression in gastric cancer. PMID: 24743909 Ref: Targeting receptor tyrosine kinases in gastric cancer. PMID: 24782606 Ref: Anti-tumor activity of oridonin on SNU-5 subcutaneous xenograft model via regulation of c-Met pathway. PMID: 24916572 Ref: Gastric cancer--epidemiologic and clinical aspects. PMID: 25167943 Ref: Prognostic impact of the c-MET polymorphism on the clinical outcome in locoregional gastric cancer patients. PMID: 25203738 Ref: Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in solid tumors. PMID: 25275109 Ref: [Influence of 17AAG on proliferation and invasion of gastric cancer cell and its mechanism]. PMID: 25341914 Ref: Gastric Cancer: New Drugs - New Strategies. PMID: 26674336 |
Ref: Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models. PMID: 25248999 Ref: Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib. PMID: 25395073 Ref: Essential role of Her3 in two signaling transduction patterns: Her2/Her3 and MET/Her3 in proliferation of human gastric cancer. PMID: 25400108 Ref: Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer. PMID: 25424197 Ref: Metastasis-associated in colon cancer-1 upregulates vascular endothelial growth factor-C/D to promote lymphangiogenesis in human gastric cancer. PMID: 25444928 Ref: Clinical significance of hepatocyte growth factor/c-Met expression in the assessment of gastric cancer progression. PMID: 25592281 Ref: CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PMID: 25658601 Ref: Targeted therapy in gastric cancer. PMID: 25706252 Ref: Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis. PMID: 25727320 Ref: Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2. PMID: 25895023 Ref: Emerging kinase inhibitors of the treatment of gastric cancer. PMID: 26021342 Ref: c-Met targeting in advanced gastric cancer: An open challenge. PMID: 26049023 Ref: LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer. PMID: 26136075 Ref: MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway. PMID: 26186594 Ref: Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor x c-MET Bispecific Antibody. PMID: 26260789 Ref: Heterogeneity of c-Met expression in Chinese gastric cancer patients. PMID: 26472163 Ref: Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis. PMID: 26587992 Ref: Complementary PTM Profiling of Drug Response in Human Gastric Carcinoma by Immunoaffinity and IMAC Methods with Total Proteome Analysis. PMID: 28248267 |
Ref: Prognostic impact of HER2, EGFR, and c-MET status on overall survival of advanced gastric cancer patients. PMID: 25682441 Ref: Gastrokine 1 inhibits gastrin-induced cell proliferation. PMID: 25752269 Ref: MET in gastric cancer--discarding a 10% cutoff rule. PMID: 26033401 Ref: Comprehensive analyses using next-generation sequencing and immunohistochemistry enable precise treatment in advanced gastric cancer. PMID: 26489445 Ref: Rab11-FIP2 promotes the metastasis of gastric cancer cells. PMID: 26502090 Ref: Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis. PMID: 26676563 Ref: Molecular targeted therapy for the treatment of gastric cancer. PMID: 26728266 Ref: Discovery of substituted pyrazol-4-yl pyridazinone derivatives as novel c-Met kinase inhibitors. PMID: 26753914 Ref: Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors. PMID: 26795388 Ref: Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells. PMID: 26801760 Ref: Targeted therapies in gastric cancer and future perspectives. PMID: 26811601 Ref: Advances of Molecular Targeted Therapy in Gastric Cancer. PMID: 26875080 Ref: Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. PMID: 26879245 Ref: Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells. PMID: 26893681 Ref: Mesothelin Expression in Advanced Gastroesophageal Cancer Represents a Novel Target for Immunotherapy. PMID: 26894650 Ref: Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays. PMID: 27001313 Ref: A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors. PMID: 27144973 Ref: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells. PMID: 27147579 Ref: Recent insights in the therapeutic management of patients with gastric cancer. PMID: 27156069 Ref: Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities. PMID: 27191264 Ref: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management. PMID: 27217696 Ref: Current and emerging therapies in unresectable and recurrent gastric cancer. PMID: 27239108 Ref: Inhibition of long non-coding RNA TUG1 on gastric cancer cell transference and invasion through regulating and controlling the expression of miR-144/c-Met axis. PMID: 27261864 Ref: The predictors of response to neoadjuvant chemotherapy in patients with locally advanced gastric cancer. PMID: 27314292 Ref: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1. PMID: 27529686 Ref: The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer. PMID: 27539855 Ref: Direct targeting of HGF by miR-16 regulates proliferation and migration in gastric cancer. PMID: 27683052 Ref: Evaluation of c-Met, HGF, and HER-2 expressions in gastric carcinoma and their association with other clinicopathological factors. PMID: 27703380 Ref: The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study. PMID: 27729801 Ref: Clinicopathological Significance and Diagnostic Accuracy of c-MET Expression by Immunohistochemistry in Gastric Cancer: A Meta-Analysis. PMID: 27752391 |
Ref: In vivo targeting of c-Met using a non-standard macrocyclic peptide in gastric carcinoma. PMID: 27810404 Ref: Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways. PMID: 28292264 Ref: Increased HGF Expression Induces Resistance to c-MET Tyrosine Kinase Inhibitors in Gastric Cancer. PMID: 28314274 Ref: Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis. PMID: 28393839 Ref: A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer. PMID: 28404966 Ref: Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization. PMID: 28411455 Ref: Efficacy and safety of different molecular targeted agents based on chemotherapy for gastric cancer patients treatment: a network meta-analysis. PMID: 28477027 Ref: Target identification, lead optimization and antitumor evaluation of some new 1,2,4-triazines as c-Met kinase inhibitors. PMID: 28715754 Ref: Biologic therapy in esophageal and gastric malignancies: current therapies and future directions. PMID: 28736629 Ref: siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells. PMID: 28881753 Ref: Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas. PMID: 28890386 Ref: Role of Recepteur D'origine Nantais on Gastric Cancer Development and Progression. PMID: 29026705 Ref: Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer. PMID: 29094049 Ref: MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines. PMID: 29285287 |
Ref: Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors. PMID: 29416720 Ref: Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis. PMID: 29422968 Ref: MACC1 and HGF are associated with survival in patients with gastric cancer. PMID: 29435059 Ref: The Chemokine Receptor CXCR4 and c-MET Cooperatively Promote Epithelial-Mesenchymal Transition in Gastric Cancer Cells. PMID: 29494948 Ref: Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells. PMID: 29781036 Ref: Human epidermal growth factor receptor 2-, epidermal growth factor receptor-, and mesenchymal epithelial transition factor-positive sites of gastric cancer using surgical samples. PMID: 29951752 Ref: Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with in vitro Anti-Tumor Effects. PMID: 30060294 Ref: Current advances of targeting HGF/c-Met pathway in gastric cancer. PMID: 30069449 Ref: HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis. PMID: 30158543 Ref: Human chorionic gonadotropin promotes cell proliferation through the activation of c-Met in gastric cancer cells. PMID: 30197669 Ref: The safety of apatinib for the treatment of gastric cancer. PMID: 30324820 Ref: Changes in HER2 Expression and Amplification Status Following Preoperative Chemotherapy for Gastric Cancer. PMID: 30348707 |