Primary Site >> Colorectal Cancer
Gene >> MDM4
| 1. | |||||||||||
| Journal: | Pharm Res. 2001 Aug;18(8):1102-9. | ||||||||||
| Title: | Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. | ||||||||||
| Author: | Cummins, C L|Mangravite, L M|Benet, L Z | ||||||||||
| PMID: | 11587480 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Pharmacol. 2001 Mar 1;61(5):555-63. | ||||||||||
| Title: | Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status. | ||||||||||
| Author: | Lin-Lee, Y C|Tatebe, S|Savaraj, N|Ishikawa, T|Tien Kuo, M | ||||||||||
| PMID: | 11239498 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Pharmacol. 2003 Mar;63(3):742-50. | ||||||||||
| Title: | Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors. | ||||||||||
| Author: | Briz, Oscar|Macias, Rocio I R|Vallejo, Marta|Silva, Augusto|Serrano, Maria Angeles|Marin, Jose J G | ||||||||||
| PMID: | 12606785 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Pharmacol. 2003 Aug;64(2):382-94. | ||||||||||
| Title: | Molecular modes of action of artesunate in tumor cell lines. | ||||||||||
| Author: | Efferth, Thomas|Sauerbrey, Axel|Olbrich, Armin|Gebhart, Erich|Rauch, Pia|Weber, H Oliver|Hengstler, Jan G|Halatsch, Marc-Eric|Volm, Manfred|Tew, Kenneth D|Ross, Douglas D|Funk, Jens Oliver | ||||||||||
| PMID: | 12869643 | ||||||||||
| 5. | |||||||||||
| Journal: | Inflamm Bowel Dis. 2007 Jun;13(6):710-20. | ||||||||||
| Title: | Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels. | ||||||||||
| Author: | Blokzijl, Hans|Vander Borght, Sara|Bok, Lisette I H|Libbrecht, Louis|Geuken, Mariska|van den Heuvel, Fiona A J|Dijkstra, Gerard|Roskams, Tania A D|Moshage, Han|Jansen, Peter L M|Faber, Klaas Nico | ||||||||||
| PMID: | 17262809 | ||||||||||
| 6. | |||||||||||
| Journal: | Mol Cell Biol. 2008 Mar;28(6):1999-2010. | ||||||||||
| Title: | Regulation of MDMX expression by mitogenic signaling. | ||||||||||
| Author: | Gilkes, Daniele M|Pan, Yu|Coppola, Domenico|Yeatman, Timothy|Reuther, Gary W|Chen, Jiandong | ||||||||||
| PMID: | 18172009 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2008 Nov 6;27(52):6657-66. | ||||||||||
| Title: | Full-length hdmX transcripts decrease following genotoxic stress. | ||||||||||
| Author: | Markey, M|Berberich, S J | ||||||||||
| PMID: | 18711402 | ||||||||||
| 8. | |||||||||||
| Journal: | Carcinogenesis. 2010 Jun;31(6):1003-9. | ||||||||||
| Title: | Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. | ||||||||||
| Author: | Ku, Ja-Lok|Shin, Young-Kyoung|Kim, Duck-Woo|Kim, Kyung-Hee|Choi, Jin-Sung|Hong, Sung-Hye|Jeon, You-Kyung|Kim, Sung-Hee|Kim, Hong-Sun|Park, Jae-Hyun|Kim, Il-Jin|Park, Jae-Gahb | ||||||||||
| PMID: | 20176655 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncol Rep. 2011 Jul;26(1):49-54. | ||||||||||
| Title: | Rare MDM4 gene amplification in colorectal cancer: The principle of a mutually exclusive relationship between MDM alteration and TP53 inactivation is not applicable. | ||||||||||
| Author: | Suda, Tetsuji|Yoshihara, Mitsuyo|Nakamura, Yoshiyasu|Sekiguchi, Hironobu|Godai, Ten-I|Sugano, Nobuhiro|Tsuchida, Kazuhito|Shiozawa, Manabu|Sakuma, Yuji|Tsuchiya, Eiju|Kameda, Yoichi|Akaike, Makoto|Matsukuma, Shoichi|Miyagi, Yohei | ||||||||||
| PMID: | 21503588 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e42034. | ||||||||||
| Title: | MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame. | ||||||||||
| Author: | Mandke, Pooja|Wyatt, Nicholas|Fraser, Jillian|Bates, Benjamin|Berberich, Steven J|Markey, Michael P | ||||||||||
| PMID: | 22870278 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS Biol. 2014 Mar 25;12(3):e1001819. | ||||||||||
| Title: | JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. | ||||||||||
| Author: | Wang, Feng|He, Lin|Huangyang, Peiwei|Liang, Jing|Si, Wenzhe|Yan, Ruorong|Han, Xiao|Liu, Shumeng|Gui, Bin|Li, Wanjin|Miao, Di|Jing, Chao|Liu, Zhihua|Pei, Fei|Sun, Luyang|Shang, Yongfeng | ||||||||||
| PMID: | 24667498 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2014 Dec 15;74(24):7487-97. | ||||||||||
| Title: | FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. | ||||||||||
| Author: | Ling, Xiang|Xu, Chao|Fan, Chuandong|Zhong, Kai|Li, Fengzhi|Wang, Xinjiang | ||||||||||
| PMID: | 25512388 | ||||||||||
| 13. | |||||||||||
| Journal: | J Med Chem. 2015 Mar 12;58(5):2452-64. | ||||||||||
| Title: | Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer. | ||||||||||
| Author: | Ai, Yong|Kang, Fenghua|Huang, Zhangjian|Xue, Xiaowen|Lai, Yisheng|Peng, Sixun|Tian, Jide|Zhang, Yihua | ||||||||||
| PMID: | 25675144 | ||||||||||
| 14. | |||||||||||
| Journal: | Chem Pharm Bull (Tokyo). 2016;64(1):34-41. | ||||||||||
| Title: | Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex. | ||||||||||
| Author: | Rezk, Mohamed Salah|Abdel-Halim, Mohammad|Keeton, Adam|Franklin, Derek|Bauer, Matthias|Boeckler, Frank Michael|Engel, Matthias|Hartmann, Rolf Wolfgang|Zhang, Yanping|Piazza, Gary Anthony|Abadi, Ashraf Hassan | ||||||||||
| PMID: | 26726742 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Pept Res Ther. 2016 Mar 1;22(1):67-81. | ||||||||||
| Title: | Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-Alkylation. | ||||||||||
| Author: | Micewicz, Ewa D|Sharma, Shantanu|Waring, Alan J|Luong, Hai T|McBride, William H|Ruchala, Piotr | ||||||||||
| PMID: | 26957954 | ||||||||||
| 16. | |||||||||||
| Journal: | J Gastrointest Oncol. 2017 Feb;8(1):164-172. | ||||||||||
| Title: | Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. | ||||||||||
| Author: | Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K | ||||||||||
| PMID: | 28280620 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 14;8(11):18322-18336. | ||||||||||
| Title: | The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study. | ||||||||||
| Author: | Zheng, Hua-Chuan|He, Hao-Yu|Wu, Ji-Cheng|Li, Jing|Zhao, Shuang|Zhao, Gui-Feng|Jiang, Hua-Mao|Yu, Xue-Wen|Li, Zhi-Jie | ||||||||||
| PMID: | 28407690 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Lett. 2018 Feb;15(2):1673-1679. | ||||||||||
| Title: | MiR-370 promotes apoptosis in colon cancer by directly targeting MDM4. | ||||||||||
| Author: | Shen, Xiaogang|Zuo, Xiaofei|Zhang, Wenjin|Bai, Yifeng|Qin, Xianpeng|Hou, Nengyi | ||||||||||
| PMID: | 29434862 | ||||||||||
| 19. | |||||||||||
| Journal: | Br J Pharmacol. 2018 Oct;175(20):3947-3962. | ||||||||||
| Title: | Improving anticancer activity towards colon cancer cells with a new p53-activating agent. | ||||||||||
| Author: | Raimundo, Liliana|Espadinha, Margarida|Soares, Joana|Loureiro, Joana B|Alves, Marco G|Santos, Maria M M|Saraiva, Lucilia | ||||||||||
| PMID: | 30076608 | ||||||||||