Primary Site >> Pancreatic Cancer

Gene >> MDM2

Journal: Int J Oncol. 1994 Dec;5(6):1279-84.
Title: Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma.
Author: Ebert, M|Yokoyama, M|Kobrin, M|Friess, H|Buchler, M|Korc, M
PMID: 21559710
Journal: Zhonghua Bing Li Xue Za Zhi. 1996 Aug;25(4):232-5.
Title: [Studies on MDM2 oncogene expression and its effect on pancreatic carcinoma cells].
Author: Guo, H|Liu, T|Gao, J
PMID: 9275659
Journal: Chin Med J (Engl). 1998 Dec;111(12):1102-6.
Title: Inhibiting effect of murine double minute-2 oncogene on apoptosis induced by retroviral-mediated wild-type p53.
Author: Guo, H|Liu, T|Gao, J
PMID: 11263374
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1998 Dec;20(6):401-6.
Title: [Murine Doube Minute 2 oncogene inhibited apoptosis induced by retroviral-mediated wild-type p53].
Author: Guo, H|Liu, T|Gao, J
PMID: 11717930
Journal: Mutat Res. 1998 May 25;400(1-2):421-37.
Title: Accumulation of genetic alterations and their significance in each primary human cancer and cell line.
Author: Murakami, Y|Sekiya, T
PMID: 9685701
Journal: Oncogene. 1999 Jul 1;18(26):3810-20.
Title: Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus.
Author: Robertson, K D|Jones, P A
PMID: 10445844
Journal: J Nippon Med Sch. 2000 Jun;67(3):177-85.
Title: Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma.
Author: Ogata, M|Naito, Z|Tanaka, S|Moriyama, Y|Asano, G
PMID: 10851351
Journal: Mod Pathol. 2001 Feb;14(2):47-53.
Title: Deregulated expression of cell cycle-associated proteins in solid pseudopapillary tumor of the pancreas.
Author: Muller-Hocker, J|Zietz, C H|Sendelhofert, A
PMID: 11235905
Journal: Mol Cell Biol. 2001 May;21(9):3192-205.
Title: Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
Author: Woods, D|Cherwinski, H|Venetsanakos, E|Bhat, A|Gysin, S|Humbert, M|Bray, P F|Saylor, V L|McMahon, M
PMID: 11287623
Journal: Ann Surg. 2002 Jan;235(1):51-9.
Title: p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb.
Author: Gerdes, Berthold|Ramaswamy, Annette|Ziegler, Andreas|Lang, Sven A|Kersting, Michael|Baumann, Renate|Wild, Anja|Moll, Roland|Rothmund, Matthias|Bartsch, Detlef K
PMID: 11753042
Journal: Cancer Sci. 2003 May;94(5):467-72.
Title: Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor.
Author: Sato, Toshiyuki|Odagiri, Hiroki|Ikenaga, Shojiro-Kazunori|Maruyama, Masateru|Sasaki, Mutsuo
PMID: 12824895
Journal: Zhonghua Bing Li Xue Za Zhi. 2004 Apr;33(2):130-4.
Title: [Expression of proteins in p53 (p14ARF-mdm2-p53-p21WAF/CIP1) pathway and their significance in exocrine pancreatic carcinoma].
Author: Yu, Guan-zhen|Zhu, Ming-hua|Ni, Can-rong|Li, Fang-mei|Zheng, Jian-ming|Gong, Zhi-jin
PMID: 15132849
Journal: World J Gastroenterol. 2005 Apr 14;11(14):2162-5.
Title: Clinicopathological significance of p53 and mdm2 protein expression in human pancreatic cancer.
Author: Dong, Ming|Ma, Gang|Tu, Wei|Guo, Ke-Jian|Tian, Yu-Lin|Dong, Yu-Ting
PMID: 15810085
Journal: Zhonghua Bing Li Xue Za Zhi. 2005 Jul;34(7):389-92.
Title: [Mucinous noncystic (colloid) adenocarcinoma of the pancreas].
Author: Zhu, Ming-hua|Hu, Xian-gui|Ni, Can-rong|Zhang, Shun-min|Xi, Peng-cheng|Yu, Guan-zhen
PMID: 16251039
Journal: Ai Zheng. 2005 Nov;24(11):1398-403.
Title: [Expression and clinical significance of P53 pathway-associated proteins in pancreatic carcinoma].
Author: Yu, Guan-Zhen|Zhu, Ming-Hua|Chen, Ying|Ni, Can-Rong|Li, Fang-Mei
PMID: 16552971
Journal: Mol Cancer Ther. 2006 Jun;5(6):1387-95.
Title: Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer.
Author: Giovannetti, Elisa|Mey, Valentina|Nannizzi, Sara|Pasqualetti, Giuseppe|Del Tacca, Mario|Danesi, Romano
PMID: 16818496
Journal: Cell Cycle. 2007 Jul 15;6(14):1741-7. Epub 2007 May 10.
Title: p14ARF regulates E2F-1 ubiquitination and degradation via a p53-dependent mechanism.
Author: Rizos, Helen|Scurr, Lyndee L|Irvine, Mal|Alling, Nikki J|Kefford, Richard F
PMID: 17630509
Journal: Biochem Pharmacol. 2008 Feb 15;75(4):787-809. Epub 2007 Aug 19.
Title: Curcumin as "Curecumin": from kitchen to clinic.
Author: Goel, Ajay|Kunnumakkara, Ajaikumar B|Aggarwal, Bharat B
PMID: 17900536
Journal: Clin Cancer Res. 2008 Jun 15;14(12):4010-5.
Title: MDM2 promoter polymorphism and pancreatic cancer risk and prognosis.
Author: Asomaning, Kofi|Reid, Amy E|Zhou, Wei|Heist, Rebecca S|Zhai, Rihong|Su, Li|Kwak, Eunice L|Blaszkowsky, Lawrence|Zhu, Andrew X|Ryan, David P|Christiani, David C|Liu, Geoffrey
PMID: 18559624
Journal: Ann Surg Oncol. 2009 Feb;16(2):431-9.
Title: Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.
Author: Chen, Jinyun|Li, Donghui|Killary, Ann M|Sen, Subrata|Amos, Christopher I|Evans, Douglas B|Abbruzzese, James L|Frazier, Marsha L
PMID: 19020940
Journal: Oncogene. 2009 Feb 5;28(5):709-20.
Title: Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells.
Author: Sui, X|Shin, S|Zhang, R|Firozi, P F|Yang, L|Abbruzzese, J L|Reddy, S A G
PMID: 19029954
Journal: Cancer Lett. 2009 Jun 18;278(2):241-248.
Title: Novel ginsenosides 25-OH-PPD and 25-OCH3-PPD as experimental therapy for pancreatic cancer: anticancer activity and mechanisms of action.
Author: Wang, Wei|Rayburn, Elizabeth R|Zhao, Yuqing|Wang, Hui|Zhang, Ruiwen
PMID: 19203832
Journal: Pancreas. 2009 Jul;38(5):565-71.
Title: Clinicopathological correlations of cyclooxygenase-2, MDM2, and p53 expressions in surgically resectable pancreatic invasive ductal adenocarcinoma.
Author: Hermanova, Marketa|Karasek, Petr|Nenutil, Rudolf|Kyr, Michal|Tomasek, Jiri|Baltasova, Ivana|Dite, Petr
PMID: 19346994
Journal: Int J Oncol. 2009 Jun;34(6):1637-43.
Title: Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening.
Author: Lee, Su-Jin|Jung, Youn-Sang|Lee, Sun-Hye|Chung, Hye-Young|Park, Bum-Joon
PMID: 19424582
Journal: Int J Cancer. 2010 Jan 15;126(2):395-404.
Title: Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53.
Author: Zhou, Renyuan|Shanas, Renee|Nelson, Mark A|Bhattacharyya, Achyut|Shi, Jiaqi
PMID: 19609950
Journal: Neuroendocrinology. 2010;91(2):131-41.
Title: Spectral karyotypic and comparative genomic analysis of the endocrine pancreatic tumor cell line BON-1.
Author: Lopez, Juan R|Claessen, Sandra M H|Macville, Merryn V E|Albrechts, Jozefa C M|Skogseid, Britt|Speel, Ernst-Jan M
PMID: 19887762
Journal: Eur J Cancer. 2010 Apr;46(6):1122-31.
Title: MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function.
Author: Azmi, Asfar S|Aboukameel, Amro|Banerjee, Sanjeev|Wang, Zhiwei|Mohammad, Momin|Wu, Jack|Wang, Shaomeng|Yang, Dajun|Philip, Philip A|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 20156675
Journal: Curr Cancer Drug Targets. 2010 May;10(3):319-31.
Title: Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy.
Author: Azmi, Asfar S|Philip, Philip A|Aboukameel, A|Wang, Zhiwei|Banerjee, Sanjeev|Zafar, Syed F|Goustin, Anton-Scott|Almhanna, K|Yang, Dajun|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 20370686
Journal: Mini Rev Med Chem. 2010 Jun;10(6):518-26.
Title: MDM2 inhibitors for pancreatic cancer therapy.
Author: Azmi, Asfar S|Philip, Philip A|Almhanna, Khaldoun|Beck, Frances W|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 20377522
Journal: Genes Cancer. 2010 May 15;1(4):360-368.
Title: Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway.
Author: Hu, Wenwei|Feng, Zhaohui|Modica, Ippolito|Klimstra, David S|Song, Lin|Allen, Peter J|Brennan, Murray F|Levine, Arnold J|Tang, Laura H
PMID: 20871795
Journal: J Biol Chem. 2011 Aug 19;286(33):28761-71.
Title: Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid.
Author: Singh, Shiv K|Baumgart, Sandra|Singh, Garima|Konig, Alexander O|Reutlinger, Kristina|Hofbauer, Lorenz C|Barth, Peter|Gress, Thomas M|Lomberk, Gwen|Urrutia, Raul|Fernandez-Zapico, Martin E|Ellenrieder, Volker
PMID: 21628454
Journal: J Biol Chem. 2012 Jan 2;287(1):641-9.
Title: Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
Author: Ding, Jie|Polier, Gernot|Kohler, Rebecca|Giaisi, Marco|Krammer, Peter H|Li-Weber, Min
PMID: 22086925
Journal: Zhonghua Wai Ke Za Zhi. 2013 Oct;51(10):916-21.
Title: [Correlation between Gli1 expression and clinicopathological significance in human pancreatic cancer].
Author: Sheng, Wei-wei|Dong, Ming|Zhou, Jian-ping|Liu, Qing-feng|Li, Xin|Dong, Qi
PMID: 24433772
Journal: Int J Cancer. 2013 May 15;132(10):2248-57.
Title: Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.
Author: Conradt, Laura|Henrich, Annika|Wirth, Matthias|Reichert, Maximilian|Lesina, Marina|Algul, Hana|Schmid, Roland M|Kramer, Oliver H|Saur, Dieter|Schneider, Gunter
PMID: 23115126
Journal: Cell Tissue Res. 2013 Nov;354(2):521-32.
Title: Cooperation among Numb, MDM2 and p53 in the development and progression of pancreatic cancer.
Author: Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng
PMID: 23881403
Journal: Mol Cell Biochem. 2014 Feb;387(1-2):1-8.
Title: RNA interference against MDM2 suppresses tumor growth and metastasis in pancreatic carcinoma SW1990HM cells.
Author: Shi, Weidong|Meng, Zhiqiang|Chen, Zhen|Hua, Yongqiang|Gao, Huifeng|Wang, Peng|Lin, Junhua|Zhou, Zhenhua|Luo, Jianmin|Liu, Luming
PMID: 22200978
Journal: J Cell Physiol. 2014 Jul;229(7):887-97.
Title: Overexpression of calreticulin contributes to the development and progression of pancreatic cancer.
Author: Sheng, Weiwei|Chen, Chuanping|Dong, Ming|Zhou, Jianping|Liu, Qingfeng|Dong, Qi|Li, Feng
PMID: 24264800
Journal: Histopathology. 2014 Mar;64(4):523-35.
Title: The clinicopathological significance and relationship of Gli1, MDM2 and p53 expression in resectable pancreatic cancer.
Author: Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng
PMID: 24289472
Journal: Tumour Biol. 2014 Apr;35(4):3431-8.
Title: MDM2 SNP309 is an ethnicity-dependent risk factor for digestive tract cancers.
Author: Chen, Bo|Cao, Lei|Hu, Kong-Wang|Zhang, Jia-Wei|Meng, Xiang-Ling|Xiong, Mao-Ming
PMID: 24338709
Journal: World J Gastroenterol. 2014 Jan 7;20(1):193-203.
Title: Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells.
Author: Ma, Hong-Bing|Huang, Shan|Yin, Xiao-Ran|Zhang, Yang|Di, Zheng-Li
PMID: 24415872
Journal: Invest New Drugs. 2014 Oct;32(5):783-94.
Title: PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines.
Author: Izetti, Patricia|Hautefeuille, Agnes|Abujamra, Ana Lucia|de Farias, Caroline Brunetto|Giacomazzi, Juliana|Alemar, Barbara|Lenz, Guido|Roesler, Rafael|Schwartsmann, Gilberto|Osvaldt, Alessandro Bersch|Hainaut, Pierre|Ashton-Prolla, Patricia
PMID: 24838627
Journal: J Pathol. 2014 Oct;234(2):214-27.
Title: Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer.
Author: Martinez-Bosch, Neus|Iglesias, Mar|Munne-Collado, Jessica|Martinez-Caceres, Carlos|Moreno, Mireia|Guerra, Carmen|Yelamos, Jose|Navarro, Pilar
PMID: 24889936
Journal: Tumour Biol. 2014 Oct;35(10):9927-34.
Title: Netrin-1 promoted pancreatic cancer cell proliferation by upregulation of Mdm2.
Author: Huang, Qian|Hua, Hong-Wei|Jiang, Feng|Liu, Dai-He|Ding, Gang
PMID: 25001177
Journal: Gastroenterology. 2014 Oct;147(4):893-902.e2.
Title: Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.
Author: Wang, Wei|Qin, Jiang-Jiang|Voruganti, Sukesh|Wang, Ming-Hai|Sharma, Horrick|Patil, Shivaputra|Zhou, Jianwei|Wang, Hui|Mukhopadhyay, Debabrata|Buolamwini, John K|Zhang, Ruiwen
PMID: 25016295
Journal: J Pathol. 2014 Oct;234(2):228-38.
Title: A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.
Author: Yamaguchi, Takashi|Ikehara, Sanae|Nakanishi, Hayao|Ikehara, Yuzuru
PMID: 25042889
Journal: Oncotarget. 2014 Aug 15;5(15):6142-67.
Title: AKT regulates NPM dependent ARF localization and p53mut stability in tumors.
Author: Hamilton, Garth|Abraham, Aswin G|Morton, Jennifer|Sampson, Oliver|Pefani, Dafni E|Khoronenkova, Svetlana|Grawenda, Anna|Papaspyropoulos, Angelos|Jamieson, Nigel|McKay, Colin|Sansom, Owen|Dianov, Grigory L|O'Neill, Eric
PMID: 25071014
Journal: Zhonghua Wai Ke Za Zhi. 2014 Jul;52(7):518-22.
Title: [The role of Gli1 in the invasion and migration of pancreatic cancer cells].
Author: Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Liu, Qingfeng|Li, Xin|Dong, Qi
PMID: 25262609
Journal: Zhonghua Wai Ke Za Zhi. 2014 Sep;52(9):675-81.
Title: [The relationship and clinicopathological significance of Numb,MDM2 and p53 expression in human pancreatic cancer].
Author: Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng
PMID: 25410780
Journal: Cell Cycle. 2014;13(18):2962-74.
Title: Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
Author: Lv, Hongjun|Liu, Rui|Fu, Jiao|Yang, Qi|Shi, Jing|Chen, Pu|Ji, Meiju|Shi, Bingyin|Hou, Peng
PMID: 25486483
Journal: Cancer Gene Ther. 2015 Sep;22(9):445-53.
Title: Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.
Author: Takei, Y|Okamoto, S|Kawamura, K|Jiang, Y|Morinaga, T|Shingyoji, M|Sekine, I|Kubo, S|Tada, Y|Tatsumi, K|Shimada, H|Hiroshima, K|Yamaguchi, N|Tagawa, M
PMID: 26251031
Journal: Clin Cancer Res. 2015 Dec 15;21(24):5563-77.
Title: The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).
Author: Vena, Francesca|Li Causi, Eleonora|Rodriguez-Justo, Manuel|Goodstal, Samantha|Hagemann, Thorsten|Hartley, John A|Hochhauser, Daniel
PMID: 26228206
Journal: Nucleic Acid Ther. 2015 Aug;25(4):198-208.
Title: Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines.
Author: Villalobos, Xenia|Rodriguez, Laura|Sole, Anna|Lliberos, Carolina|Mencia, Nuria|Ciudad, Carlos J|Noe, Veronique
PMID: 26042602
Journal: Cancer Lett. 2016 Jan 28;370(2):177-84.
Title: Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer.
Author: Shirai, Yoshihiro|Shiba, Hiroaki|Iwase, Ryota|Haruki, Koichiro|Fujiwara, Yuki|Furukawa, Kenei|Uwagawa, Tadashi|Ohashi, Toya|Yanaga, Katsuhiko
PMID: 26546875
Journal: Br J Dermatol. 2016 Oct;175(4):785-9.
Title: CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature.
Author: Sargen, M R|Merrill, S L|Chu, E Y|Nathanson, K L
PMID: 26876133
Journal: Transl Gastroenterol Hepatol. 2016 Sep 23;1:73.
Title: Metastatic multiple endocrine neoplasia type 1: report of one case.
Author: Huang, Cheng|Zhu, Xiaodong|Han, Xu|Lou, Wenhui
PMID: 28138639
Journal: Sheng Li Xue Bao. 2017 Dec 25;69(6):759-766.
Title: Caveolin-1 is involved in DNA damage and repair signaling in X-irradiated Chang liver cells.
Author: Li, Hong-Yan|Qu, Chao|Zhang, Ye-Jun|Sun, Jia|Han, Chao|Liu, Jing|Zou, Wei
PMID: 29270591
Journal: Drug Des. 2017 Mar;6(1).
Title: Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b]indole Derivatives as Broad-Spectrum Potent Anticancer Agents.
Author: Patil, Shivaputra A|Addo, James K|Deokar, Hemantkumar|Sun, Shan|Wang, Jin|Li, Wei|Suttle, D Parker|Wang, Wei|Zhang, Ruiwen|Buolamwini, John K
PMID: 29354330
Journal: PLoS One. 2017 Dec 6;12(12):e0189051.
Title: Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.
Author: Saison-Ridinger, Maya|DelGiorno, Kathleen E|Zhang, Tejia|Kraus, Annabelle|French, Randall|Jaquish, Dawn|Tsui, Crystal|Erikson, Galina|Spike, Benjamin T|Shokhirev, Maxim N|Liddle, Christopher|Yu, Ruth T|Downes, Michael|Evans, Ronald M|Saghatelian, Alan|Low
PMID: 29211796
Journal: Onco Targets Ther. 2017 Sep 11;10:4455-4464.
Title: miR-509-5p inhibits cellular proliferation and migration via targeting MDM2 in pancreatic cancer cells.
Author: Li, Xin|Li, Yan|Wan, Li|Chen, Rui|Chen, Fei
PMID: 28979137
Journal: PLoS One. 2017 Jul 5;12(7):e0180628.
Title: Association of MDM2 expression with shorter progression-free survival and overall survival in patients with advanced pancreatic cancer treated with gemcitabine-based chemotherapy.
Author: Yang, Shih-Hung|Lee, Jen-Chieh|Guo, Jhe-Cyuan|Kuo, Sung-Hsin|Tien, Yu-Wen|Kuo, Ting-Chun|Cheng, Ann-Lii|Yeh, Kun-Huei
PMID: 28678832
Journal: FASEB J. 2017 Jun;31(6):2429-2438.
Title: Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Author: Sheng, Weiwei|Dong, Ming|Chen, Chuanping|Wang, Zixin|Li, Yunwei|Wang, Kewei|Li, Yuji|Zhou, Jianping
PMID: 28223335
Journal: Int J Cancer. 2018 Apr 1;142(7):1392-1404.
Title: YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/MdM2/P53/P21 signaling pathway.
Author: Liu, Dongfang|Zhang, Jingjing|Wu, Yang|Shi, Guodong|Yuan, Hao|Lu, Zipeng|Zhu, Qicong|Wu, Pengfei|Lu, Cheng|Guo, Feng|Chen, Jianmin|Jiang, Kuirong|Miao, Yi
PMID: 29168185
Journal: Front Pharmacol. 2018 Jan 17;9:5.
Title: Inhibiting beta-Catenin by beta-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy.
Author: Qin, Jiang-Jiang|Wang, Wei|Li, Xin|Deokar, Hemantkumar|Buolamwini, John K|Zhang, Ruiwen
PMID: 29387014
Journal: Mol Cancer Res. 2018 Jun 14. pii: 1541-7786.MCR-18-0281.
Title: Daxx Functions Are p53-Independent In Vivo.
Author: Wasylishen, Amanda R|Estrella, Jeannelyn S|Pant, Vinod|Chau, Gilda P|Lozano, Guillermina
PMID: 29903771
Journal: Adv Biol Regul. 2018 Aug;69:16-34.
Title: Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.
Author: Abrams, Stephen L|Lertpiriyapong, Kvin|Yang, Li V|Martelli, Alberto M|Cocco, Lucio|Ratti, Stefano|Falasca, Marco|Murata, Ramiro M|Rosalen, Pedro L|Lombardi, Paolo|Libra, Massimo|Candido, Saverio|Montalto, Giuseppe|Cervello, Melchiorre|Steelman, Linda S|Mc
PMID: 29980405
Journal: J Cell Physiol. 2018 Aug 2.
Title: Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
Author: Zhang, Hui|Zhang, Xuan|Li, Xun|Meng, Wen-Bo|Bai, Zhong-Tian|Rui, Shao-Zhen|Wang, Zheng-Feng|Zhou, Wen-Ce|Jin, Xiao-Da
PMID: 30069972
Journal: Cancer Res. 2018 Sep 14. pii: 0008-5472.CAN-17-3939.
Title: Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy.
Author: Wang, Wei|Qin, Jiang-Jiang|Voruganti, Sukesh|Nijampatnam, Bhavitavya|Velu, Sadanandan E|Ruan, Ke-He|Hu, Ming|Zhou, Jianwei|Zhang, Ruiwen
PMID: 30217928
Journal: Mol Ther. 2018 Sep 27. pii: S1525-0016(18)30457-X.
Title: Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer.
Author: Rovira-Rigau, Maria|Raimondi, Giulia|Marin, Miguel Angel|Gironella, Meritxell|Alemany, Ramon|Fillat, Cristina
PMID: 30341009