Primary Site >> Pancreatic Cancer
Gene >> MDM2
| 1. | |||||||||||
| Journal: | Int J Oncol. 1994 Dec;5(6):1279-84. | ||||||||||
| Title: | Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Ebert, M|Yokoyama, M|Kobrin, M|Friess, H|Buchler, M|Korc, M | ||||||||||
| PMID: | 21559710 | ||||||||||
| 2. | |||||||||||
| Journal: | Zhonghua Bing Li Xue Za Zhi. 1996 Aug;25(4):232-5. | ||||||||||
| Title: | [Studies on MDM2 oncogene expression and its effect on pancreatic carcinoma cells]. | ||||||||||
| Author: | Guo, H|Liu, T|Gao, J | ||||||||||
| PMID: | 9275659 | ||||||||||
| 3. | |||||||||||
| Journal: | Chin Med J (Engl). 1998 Dec;111(12):1102-6. | ||||||||||
| Title: | Inhibiting effect of murine double minute-2 oncogene on apoptosis induced by retroviral-mediated wild-type p53. | ||||||||||
| Author: | Guo, H|Liu, T|Gao, J | ||||||||||
| PMID: | 11263374 | ||||||||||
| 4. | |||||||||||
| Journal: | Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1998 Dec;20(6):401-6. | ||||||||||
| Title: | [Murine Doube Minute 2 oncogene inhibited apoptosis induced by retroviral-mediated wild-type p53]. | ||||||||||
| Author: | Guo, H|Liu, T|Gao, J | ||||||||||
| PMID: | 11717930 | ||||||||||
| 5. | |||||||||||
| Journal: | Mutat Res. 1998 May 25;400(1-2):421-37. | ||||||||||
| Title: | Accumulation of genetic alterations and their significance in each primary human cancer and cell line. | ||||||||||
| Author: | Murakami, Y|Sekiya, T | ||||||||||
| PMID: | 9685701 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 1999 Jul 1;18(26):3810-20. | ||||||||||
| Title: | Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. | ||||||||||
| Author: | Robertson, K D|Jones, P A | ||||||||||
| PMID: | 10445844 | ||||||||||
| 7. | |||||||||||
| Journal: | J Nippon Med Sch. 2000 Jun;67(3):177-85. | ||||||||||
| Title: | Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma. | ||||||||||
| Author: | Ogata, M|Naito, Z|Tanaka, S|Moriyama, Y|Asano, G | ||||||||||
| PMID: | 10851351 | ||||||||||
| 8. | |||||||||||
| Journal: | Mod Pathol. 2001 Feb;14(2):47-53. | ||||||||||
| Title: | Deregulated expression of cell cycle-associated proteins in solid pseudopapillary tumor of the pancreas. | ||||||||||
| Author: | Muller-Hocker, J|Zietz, C H|Sendelhofert, A | ||||||||||
| PMID: | 11235905 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cell Biol. 2001 May;21(9):3192-205. | ||||||||||
| Title: | Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway. | ||||||||||
| Author: | Woods, D|Cherwinski, H|Venetsanakos, E|Bhat, A|Gysin, S|Humbert, M|Bray, P F|Saylor, V L|McMahon, M | ||||||||||
| PMID: | 11287623 | ||||||||||
| 10. | |||||||||||
| Journal: | Ann Surg. 2002 Jan;235(1):51-9. | ||||||||||
| Title: | p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb. | ||||||||||
| Author: | Gerdes, Berthold|Ramaswamy, Annette|Ziegler, Andreas|Lang, Sven A|Kersting, Michael|Baumann, Renate|Wild, Anja|Moll, Roland|Rothmund, Matthias|Bartsch, Detlef K | ||||||||||
| PMID: | 11753042 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Sci. 2003 May;94(5):467-72. | ||||||||||
| Title: | Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor. | ||||||||||
| Author: | Sato, Toshiyuki|Odagiri, Hiroki|Ikenaga, Shojiro-Kazunori|Maruyama, Masateru|Sasaki, Mutsuo | ||||||||||
| PMID: | 12824895 | ||||||||||
| 12. | |||||||||||
| Journal: | Zhonghua Bing Li Xue Za Zhi. 2004 Apr;33(2):130-4. | ||||||||||
| Title: | [Expression of proteins in p53 (p14ARF-mdm2-p53-p21WAF/CIP1) pathway and their significance in exocrine pancreatic carcinoma]. | ||||||||||
| Author: | Yu, Guan-zhen|Zhu, Ming-hua|Ni, Can-rong|Li, Fang-mei|Zheng, Jian-ming|Gong, Zhi-jin | ||||||||||
| PMID: | 15132849 | ||||||||||
| 13. | |||||||||||
| Journal: | World J Gastroenterol. 2005 Apr 14;11(14):2162-5. | ||||||||||
| Title: | Clinicopathological significance of p53 and mdm2 protein expression in human pancreatic cancer. | ||||||||||
| Author: | Dong, Ming|Ma, Gang|Tu, Wei|Guo, Ke-Jian|Tian, Yu-Lin|Dong, Yu-Ting | ||||||||||
| PMID: | 15810085 | ||||||||||
| 14. | |||||||||||
| Journal: | Zhonghua Bing Li Xue Za Zhi. 2005 Jul;34(7):389-92. | ||||||||||
| Title: | [Mucinous noncystic (colloid) adenocarcinoma of the pancreas]. | ||||||||||
| Author: | Zhu, Ming-hua|Hu, Xian-gui|Ni, Can-rong|Zhang, Shun-min|Xi, Peng-cheng|Yu, Guan-zhen | ||||||||||
| PMID: | 16251039 | ||||||||||
| 15. | |||||||||||
| Journal: | Ai Zheng. 2005 Nov;24(11):1398-403. | ||||||||||
| Title: | [Expression and clinical significance of P53 pathway-associated proteins in pancreatic carcinoma]. | ||||||||||
| Author: | Yu, Guan-Zhen|Zhu, Ming-Hua|Chen, Ying|Ni, Can-Rong|Li, Fang-Mei | ||||||||||
| PMID: | 16552971 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Cancer Ther. 2006 Jun;5(6):1387-95. | ||||||||||
| Title: | Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer. | ||||||||||
| Author: | Giovannetti, Elisa|Mey, Valentina|Nannizzi, Sara|Pasqualetti, Giuseppe|Del Tacca, Mario|Danesi, Romano | ||||||||||
| PMID: | 16818496 | ||||||||||
| 17. | |||||||||||
| Journal: | Cell Cycle. 2007 Jul 15;6(14):1741-7. Epub 2007 May 10. | ||||||||||
| Title: | p14ARF regulates E2F-1 ubiquitination and degradation via a p53-dependent mechanism. | ||||||||||
| Author: | Rizos, Helen|Scurr, Lyndee L|Irvine, Mal|Alling, Nikki J|Kefford, Richard F | ||||||||||
| PMID: | 17630509 | ||||||||||
| 18. | |||||||||||
| Journal: | Biochem Pharmacol. 2008 Feb 15;75(4):787-809. Epub 2007 Aug 19. | ||||||||||
| Title: | Curcumin as "Curecumin": from kitchen to clinic. | ||||||||||
| Author: | Goel, Ajay|Kunnumakkara, Ajaikumar B|Aggarwal, Bharat B | ||||||||||
| PMID: | 17900536 | ||||||||||
| 19. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Jun 15;14(12):4010-5. | ||||||||||
| Title: | MDM2 promoter polymorphism and pancreatic cancer risk and prognosis. | ||||||||||
| Author: | Asomaning, Kofi|Reid, Amy E|Zhou, Wei|Heist, Rebecca S|Zhai, Rihong|Su, Li|Kwak, Eunice L|Blaszkowsky, Lawrence|Zhu, Andrew X|Ryan, David P|Christiani, David C|Liu, Geoffrey | ||||||||||
| PMID: | 18559624 | ||||||||||
| 20. | |||||||||||
| Journal: | Ann Surg Oncol. 2009 Feb;16(2):431-9. | ||||||||||
| Title: | Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. | ||||||||||
| Author: | Chen, Jinyun|Li, Donghui|Killary, Ann M|Sen, Subrata|Amos, Christopher I|Evans, Douglas B|Abbruzzese, James L|Frazier, Marsha L | ||||||||||
| PMID: | 19020940 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogene. 2009 Feb 5;28(5):709-20. | ||||||||||
| Title: | Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells. | ||||||||||
| Author: | Sui, X|Shin, S|Zhang, R|Firozi, P F|Yang, L|Abbruzzese, J L|Reddy, S A G | ||||||||||
| PMID: | 19029954 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Lett. 2009 Jun 18;278(2):241-248. | ||||||||||
| Title: | Novel ginsenosides 25-OH-PPD and 25-OCH3-PPD as experimental therapy for pancreatic cancer: anticancer activity and mechanisms of action. | ||||||||||
| Author: | Wang, Wei|Rayburn, Elizabeth R|Zhao, Yuqing|Wang, Hui|Zhang, Ruiwen | ||||||||||
| PMID: | 19203832 | ||||||||||
| 23. | |||||||||||
| Journal: | Pancreas. 2009 Jul;38(5):565-71. | ||||||||||
| Title: | Clinicopathological correlations of cyclooxygenase-2, MDM2, and p53 expressions in surgically resectable pancreatic invasive ductal adenocarcinoma. | ||||||||||
| Author: | Hermanova, Marketa|Karasek, Petr|Nenutil, Rudolf|Kyr, Michal|Tomasek, Jiri|Baltasova, Ivana|Dite, Petr | ||||||||||
| PMID: | 19346994 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Oncol. 2009 Jun;34(6):1637-43. | ||||||||||
| Title: | Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening. | ||||||||||
| Author: | Lee, Su-Jin|Jung, Youn-Sang|Lee, Sun-Hye|Chung, Hye-Young|Park, Bum-Joon | ||||||||||
| PMID: | 19424582 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Cancer. 2010 Jan 15;126(2):395-404. | ||||||||||
| Title: | Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53. | ||||||||||
| Author: | Zhou, Renyuan|Shanas, Renee|Nelson, Mark A|Bhattacharyya, Achyut|Shi, Jiaqi | ||||||||||
| PMID: | 19609950 | ||||||||||
| 26. | |||||||||||
| Journal: | Neuroendocrinology. 2010;91(2):131-41. | ||||||||||
| Title: | Spectral karyotypic and comparative genomic analysis of the endocrine pancreatic tumor cell line BON-1. | ||||||||||
| Author: | Lopez, Juan R|Claessen, Sandra M H|Macville, Merryn V E|Albrechts, Jozefa C M|Skogseid, Britt|Speel, Ernst-Jan M | ||||||||||
| PMID: | 19887762 | ||||||||||
| 27. | |||||||||||
| Journal: | Eur J Cancer. 2010 Apr;46(6):1122-31. | ||||||||||
| Title: | MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function. | ||||||||||
| Author: | Azmi, Asfar S|Aboukameel, Amro|Banerjee, Sanjeev|Wang, Zhiwei|Mohammad, Momin|Wu, Jack|Wang, Shaomeng|Yang, Dajun|Philip, Philip A|Sarkar, Fazlul H|Mohammad, Ramzi M | ||||||||||
| PMID: | 20156675 | ||||||||||
| 28. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2010 May;10(3):319-31. | ||||||||||
| Title: | Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy. | ||||||||||
| Author: | Azmi, Asfar S|Philip, Philip A|Aboukameel, A|Wang, Zhiwei|Banerjee, Sanjeev|Zafar, Syed F|Goustin, Anton-Scott|Almhanna, K|Yang, Dajun|Sarkar, Fazlul H|Mohammad, Ramzi M | ||||||||||
| PMID: | 20370686 | ||||||||||
| 29. | |||||||||||
| Journal: | Mini Rev Med Chem. 2010 Jun;10(6):518-26. | ||||||||||
| Title: | MDM2 inhibitors for pancreatic cancer therapy. | ||||||||||
| Author: | Azmi, Asfar S|Philip, Philip A|Almhanna, Khaldoun|Beck, Frances W|Sarkar, Fazlul H|Mohammad, Ramzi M | ||||||||||
| PMID: | 20377522 | ||||||||||
| 30. | |||||||||||
| Journal: | Genes Cancer. 2010 May 15;1(4):360-368. | ||||||||||
| Title: | Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway. | ||||||||||
| Author: | Hu, Wenwei|Feng, Zhaohui|Modica, Ippolito|Klimstra, David S|Song, Lin|Allen, Peter J|Brennan, Murray F|Levine, Arnold J|Tang, Laura H | ||||||||||
| PMID: | 20871795 | ||||||||||
| 31. | |||||||||||
| Journal: | J Biol Chem. 2011 Aug 19;286(33):28761-71. | ||||||||||
| Title: | Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid. | ||||||||||
| Author: | Singh, Shiv K|Baumgart, Sandra|Singh, Garima|Konig, Alexander O|Reutlinger, Kristina|Hofbauer, Lorenz C|Barth, Peter|Gress, Thomas M|Lomberk, Gwen|Urrutia, Raul|Fernandez-Zapico, Martin E|Ellenrieder, Volker | ||||||||||
| PMID: | 21628454 | ||||||||||
| 32. | |||||||||||
| Journal: | J Biol Chem. 2012 Jan 2;287(1):641-9. | ||||||||||
| Title: | Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression. | ||||||||||
| Author: | Ding, Jie|Polier, Gernot|Kohler, Rebecca|Giaisi, Marco|Krammer, Peter H|Li-Weber, Min | ||||||||||
| PMID: | 22086925 | ||||||||||
| 33. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2013 Oct;51(10):916-21. | ||||||||||
| Title: | [Correlation between Gli1 expression and clinicopathological significance in human pancreatic cancer]. | ||||||||||
| Author: | Sheng, Wei-wei|Dong, Ming|Zhou, Jian-ping|Liu, Qing-feng|Li, Xin|Dong, Qi | ||||||||||
| PMID: | 24433772 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Cancer. 2013 May 15;132(10):2248-57. | ||||||||||
| Title: | Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death. | ||||||||||
| Author: | Conradt, Laura|Henrich, Annika|Wirth, Matthias|Reichert, Maximilian|Lesina, Marina|Algul, Hana|Schmid, Roland M|Kramer, Oliver H|Saur, Dieter|Schneider, Gunter | ||||||||||
| PMID: | 23115126 | ||||||||||
| 35. | |||||||||||
| Journal: | Cell Tissue Res. 2013 Nov;354(2):521-32. | ||||||||||
| Title: | Cooperation among Numb, MDM2 and p53 in the development and progression of pancreatic cancer. | ||||||||||
| Author: | Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng | ||||||||||
| PMID: | 23881403 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Cell Biochem. 2014 Feb;387(1-2):1-8. | ||||||||||
| Title: | RNA interference against MDM2 suppresses tumor growth and metastasis in pancreatic carcinoma SW1990HM cells. | ||||||||||
| Author: | Shi, Weidong|Meng, Zhiqiang|Chen, Zhen|Hua, Yongqiang|Gao, Huifeng|Wang, Peng|Lin, Junhua|Zhou, Zhenhua|Luo, Jianmin|Liu, Luming | ||||||||||
| PMID: | 22200978 | ||||||||||
| 37. | |||||||||||
| Journal: | J Cell Physiol. 2014 Jul;229(7):887-97. | ||||||||||
| Title: | Overexpression of calreticulin contributes to the development and progression of pancreatic cancer. | ||||||||||
| Author: | Sheng, Weiwei|Chen, Chuanping|Dong, Ming|Zhou, Jianping|Liu, Qingfeng|Dong, Qi|Li, Feng | ||||||||||
| PMID: | 24264800 | ||||||||||
| 38. | |||||||||||
| Journal: | Histopathology. 2014 Mar;64(4):523-35. | ||||||||||
| Title: | The clinicopathological significance and relationship of Gli1, MDM2 and p53 expression in resectable pancreatic cancer. | ||||||||||
| Author: | Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng | ||||||||||
| PMID: | 24289472 | ||||||||||
| 39. | |||||||||||
| Journal: | Tumour Biol. 2014 Apr;35(4):3431-8. | ||||||||||
| Title: | MDM2 SNP309 is an ethnicity-dependent risk factor for digestive tract cancers. | ||||||||||
| Author: | Chen, Bo|Cao, Lei|Hu, Kong-Wang|Zhang, Jia-Wei|Meng, Xiang-Ling|Xiong, Mao-Ming | ||||||||||
| PMID: | 24338709 | ||||||||||
| 40. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Jan 7;20(1):193-203. | ||||||||||
| Title: | Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells. | ||||||||||
| Author: | Ma, Hong-Bing|Huang, Shan|Yin, Xiao-Ran|Zhang, Yang|Di, Zheng-Li | ||||||||||
| PMID: | 24415872 | ||||||||||
| 41. | |||||||||||
| Journal: | Invest New Drugs. 2014 Oct;32(5):783-94. | ||||||||||
| Title: | PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines. | ||||||||||
| Author: | Izetti, Patricia|Hautefeuille, Agnes|Abujamra, Ana Lucia|de Farias, Caroline Brunetto|Giacomazzi, Juliana|Alemar, Barbara|Lenz, Guido|Roesler, Rafael|Schwartsmann, Gilberto|Osvaldt, Alessandro Bersch|Hainaut, Pierre|Ashton-Prolla, Patricia | ||||||||||
| PMID: | 24838627 | ||||||||||
| 42. | |||||||||||
| Journal: | J Pathol. 2014 Oct;234(2):214-27. | ||||||||||
| Title: | Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer. | ||||||||||
| Author: | Martinez-Bosch, Neus|Iglesias, Mar|Munne-Collado, Jessica|Martinez-Caceres, Carlos|Moreno, Mireia|Guerra, Carmen|Yelamos, Jose|Navarro, Pilar | ||||||||||
| PMID: | 24889936 | ||||||||||
| 43. | |||||||||||
| Journal: | Tumour Biol. 2014 Oct;35(10):9927-34. | ||||||||||
| Title: | Netrin-1 promoted pancreatic cancer cell proliferation by upregulation of Mdm2. | ||||||||||
| Author: | Huang, Qian|Hua, Hong-Wei|Jiang, Feng|Liu, Dai-He|Ding, Gang | ||||||||||
| PMID: | 25001177 | ||||||||||
| 44. | |||||||||||
| Journal: | Gastroenterology. 2014 Oct;147(4):893-902.e2. | ||||||||||
| Title: | Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice. | ||||||||||
| Author: | Wang, Wei|Qin, Jiang-Jiang|Voruganti, Sukesh|Wang, Ming-Hai|Sharma, Horrick|Patil, Shivaputra|Zhou, Jianwei|Wang, Hui|Mukhopadhyay, Debabrata|Buolamwini, John K|Zhang, Ruiwen | ||||||||||
| PMID: | 25016295 | ||||||||||
| 45. | |||||||||||
| Journal: | J Pathol. 2014 Oct;234(2):228-38. | ||||||||||
| Title: | A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Yamaguchi, Takashi|Ikehara, Sanae|Nakanishi, Hayao|Ikehara, Yuzuru | ||||||||||
| PMID: | 25042889 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncotarget. 2014 Aug 15;5(15):6142-67. | ||||||||||
| Title: | AKT regulates NPM dependent ARF localization and p53mut stability in tumors. | ||||||||||
| Author: | Hamilton, Garth|Abraham, Aswin G|Morton, Jennifer|Sampson, Oliver|Pefani, Dafni E|Khoronenkova, Svetlana|Grawenda, Anna|Papaspyropoulos, Angelos|Jamieson, Nigel|McKay, Colin|Sansom, Owen|Dianov, Grigory L|O'Neill, Eric | ||||||||||
| PMID: | 25071014 | ||||||||||
| 47. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2014 Jul;52(7):518-22. | ||||||||||
| Title: | [The role of Gli1 in the invasion and migration of pancreatic cancer cells]. | ||||||||||
| Author: | Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Liu, Qingfeng|Li, Xin|Dong, Qi | ||||||||||
| PMID: | 25262609 | ||||||||||
| 48. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2014 Sep;52(9):675-81. | ||||||||||
| Title: | [The relationship and clinicopathological significance of Numb,MDM2 and p53 expression in human pancreatic cancer]. | ||||||||||
| Author: | Sheng, Weiwei|Dong, Ming|Zhou, Jianping|Li, Xin|Liu, Qingfeng|Dong, Qi|Li, Feng | ||||||||||
| PMID: | 25410780 | ||||||||||
| 49. | |||||||||||
| Journal: | Cell Cycle. 2014;13(18):2962-74. | ||||||||||
| Title: | Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway. | ||||||||||
| Author: | Lv, Hongjun|Liu, Rui|Fu, Jiao|Yang, Qi|Shi, Jing|Chen, Pu|Ji, Meiju|Shi, Bingyin|Hou, Peng | ||||||||||
| PMID: | 25486483 | ||||||||||
| 50. | |||||||||||
| Journal: | Cancer Gene Ther. 2015 Sep;22(9):445-53. | ||||||||||
| Title: | Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells. | ||||||||||
| Author: | Takei, Y|Okamoto, S|Kawamura, K|Jiang, Y|Morinaga, T|Shingyoji, M|Sekine, I|Kubo, S|Tada, Y|Tatsumi, K|Shimada, H|Hiroshima, K|Yamaguchi, N|Tagawa, M | ||||||||||
| PMID: | 26251031 | ||||||||||
| 51. | |||||||||||
| Journal: | Clin Cancer Res. 2015 Dec 15;21(24):5563-77. | ||||||||||
| Title: | The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1). | ||||||||||
| Author: | Vena, Francesca|Li Causi, Eleonora|Rodriguez-Justo, Manuel|Goodstal, Samantha|Hagemann, Thorsten|Hartley, John A|Hochhauser, Daniel | ||||||||||
| PMID: | 26228206 | ||||||||||
| 52. | |||||||||||
| Journal: | Nucleic Acid Ther. 2015 Aug;25(4):198-208. | ||||||||||
| Title: | Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines. | ||||||||||
| Author: | Villalobos, Xenia|Rodriguez, Laura|Sole, Anna|Lliberos, Carolina|Mencia, Nuria|Ciudad, Carlos J|Noe, Veronique | ||||||||||
| PMID: | 26042602 | ||||||||||
| 53. | |||||||||||
| Journal: | Cancer Lett. 2016 Jan 28;370(2):177-84. | ||||||||||
| Title: | Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer. | ||||||||||
| Author: | Shirai, Yoshihiro|Shiba, Hiroaki|Iwase, Ryota|Haruki, Koichiro|Fujiwara, Yuki|Furukawa, Kenei|Uwagawa, Tadashi|Ohashi, Toya|Yanaga, Katsuhiko | ||||||||||
| PMID: | 26546875 | ||||||||||
| 54. | |||||||||||
| Journal: | Br J Dermatol. 2016 Oct;175(4):785-9. | ||||||||||
| Title: | CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature. | ||||||||||
| Author: | Sargen, M R|Merrill, S L|Chu, E Y|Nathanson, K L | ||||||||||
| PMID: | 26876133 | ||||||||||
| 55. | |||||||||||
| Journal: | Transl Gastroenterol Hepatol. 2016 Sep 23;1:73. | ||||||||||
| Title: | Metastatic multiple endocrine neoplasia type 1: report of one case. | ||||||||||
| Author: | Huang, Cheng|Zhu, Xiaodong|Han, Xu|Lou, Wenhui | ||||||||||
| PMID: | 28138639 | ||||||||||
| 56. | |||||||||||
| Journal: | Sheng Li Xue Bao. 2017 Dec 25;69(6):759-766. | ||||||||||
| Title: | Caveolin-1 is involved in DNA damage and repair signaling in X-irradiated Chang liver cells. | ||||||||||
| Author: | Li, Hong-Yan|Qu, Chao|Zhang, Ye-Jun|Sun, Jia|Han, Chao|Liu, Jing|Zou, Wei | ||||||||||
| PMID: | 29270591 | ||||||||||
| 57. | |||||||||||
| Journal: | Drug Des. 2017 Mar;6(1). | ||||||||||
| Title: | Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b]indole Derivatives as Broad-Spectrum Potent Anticancer Agents. | ||||||||||
| Author: | Patil, Shivaputra A|Addo, James K|Deokar, Hemantkumar|Sun, Shan|Wang, Jin|Li, Wei|Suttle, D Parker|Wang, Wei|Zhang, Ruiwen|Buolamwini, John K | ||||||||||
| PMID: | 29354330 | ||||||||||
| 58. | |||||||||||
| Journal: | PLoS One. 2017 Dec 6;12(12):e0189051. | ||||||||||
| Title: | Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy. | ||||||||||
| Author: | Saison-Ridinger, Maya|DelGiorno, Kathleen E|Zhang, Tejia|Kraus, Annabelle|French, Randall|Jaquish, Dawn|Tsui, Crystal|Erikson, Galina|Spike, Benjamin T|Shokhirev, Maxim N|Liddle, Christopher|Yu, Ruth T|Downes, Michael|Evans, Ronald M|Saghatelian, Alan|Low | ||||||||||
| PMID: | 29211796 | ||||||||||
| 59. | |||||||||||
| Journal: | Onco Targets Ther. 2017 Sep 11;10:4455-4464. | ||||||||||
| Title: | miR-509-5p inhibits cellular proliferation and migration via targeting MDM2 in pancreatic cancer cells. | ||||||||||
| Author: | Li, Xin|Li, Yan|Wan, Li|Chen, Rui|Chen, Fei | ||||||||||
| PMID: | 28979137 | ||||||||||
| 60. | |||||||||||
| Journal: | PLoS One. 2017 Jul 5;12(7):e0180628. | ||||||||||
| Title: | Association of MDM2 expression with shorter progression-free survival and overall survival in patients with advanced pancreatic cancer treated with gemcitabine-based chemotherapy. | ||||||||||
| Author: | Yang, Shih-Hung|Lee, Jen-Chieh|Guo, Jhe-Cyuan|Kuo, Sung-Hsin|Tien, Yu-Wen|Kuo, Ting-Chun|Cheng, Ann-Lii|Yeh, Kun-Huei | ||||||||||
| PMID: | 28678832 | ||||||||||
| 61. | |||||||||||
| Journal: | FASEB J. 2017 Jun;31(6):2429-2438. | ||||||||||
| Title: | Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer. | ||||||||||
| Author: | Sheng, Weiwei|Dong, Ming|Chen, Chuanping|Wang, Zixin|Li, Yunwei|Wang, Kewei|Li, Yuji|Zhou, Jianping | ||||||||||
| PMID: | 28223335 | ||||||||||
| 62. | |||||||||||
| Journal: | Int J Cancer. 2018 Apr 1;142(7):1392-1404. | ||||||||||
| Title: | YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/MdM2/P53/P21 signaling pathway. | ||||||||||
| Author: | Liu, Dongfang|Zhang, Jingjing|Wu, Yang|Shi, Guodong|Yuan, Hao|Lu, Zipeng|Zhu, Qicong|Wu, Pengfei|Lu, Cheng|Guo, Feng|Chen, Jianmin|Jiang, Kuirong|Miao, Yi | ||||||||||
| PMID: | 29168185 | ||||||||||
| 63. | |||||||||||
| Journal: | Front Pharmacol. 2018 Jan 17;9:5. | ||||||||||
| Title: | Inhibiting beta-Catenin by beta-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy. | ||||||||||
| Author: | Qin, Jiang-Jiang|Wang, Wei|Li, Xin|Deokar, Hemantkumar|Buolamwini, John K|Zhang, Ruiwen | ||||||||||
| PMID: | 29387014 | ||||||||||
| 64. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Jun 14. pii: 1541-7786.MCR-18-0281. | ||||||||||
| Title: | Daxx Functions Are p53-Independent In Vivo. | ||||||||||
| Author: | Wasylishen, Amanda R|Estrella, Jeannelyn S|Pant, Vinod|Chau, Gilda P|Lozano, Guillermina | ||||||||||
| PMID: | 29903771 | ||||||||||
| 65. | |||||||||||
| Journal: | Adv Biol Regul. 2018 Aug;69:16-34. | ||||||||||
| Title: | Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals. | ||||||||||
| Author: | Abrams, Stephen L|Lertpiriyapong, Kvin|Yang, Li V|Martelli, Alberto M|Cocco, Lucio|Ratti, Stefano|Falasca, Marco|Murata, Ramiro M|Rosalen, Pedro L|Lombardi, Paolo|Libra, Massimo|Candido, Saverio|Montalto, Giuseppe|Cervello, Melchiorre|Steelman, Linda S|Mc | ||||||||||
| PMID: | 29980405 | ||||||||||
| 66. | |||||||||||
| Journal: | J Cell Physiol. 2018 Aug 2. | ||||||||||
| Title: | Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. | ||||||||||
| Author: | Zhang, Hui|Zhang, Xuan|Li, Xun|Meng, Wen-Bo|Bai, Zhong-Tian|Rui, Shao-Zhen|Wang, Zheng-Feng|Zhou, Wen-Ce|Jin, Xiao-Da | ||||||||||
| PMID: | 30069972 | ||||||||||
| 67. | |||||||||||
| Journal: | Cancer Res. 2018 Sep 14. pii: 0008-5472.CAN-17-3939. | ||||||||||
| Title: | Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. | ||||||||||
| Author: | Wang, Wei|Qin, Jiang-Jiang|Voruganti, Sukesh|Nijampatnam, Bhavitavya|Velu, Sadanandan E|Ruan, Ke-He|Hu, Ming|Zhou, Jianwei|Zhang, Ruiwen | ||||||||||
| PMID: | 30217928 | ||||||||||
| 68. | |||||||||||
| Journal: | Mol Ther. 2018 Sep 27. pii: S1525-0016(18)30457-X. | ||||||||||
| Title: | Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer. | ||||||||||
| Author: | Rovira-Rigau, Maria|Raimondi, Giulia|Marin, Miguel Angel|Gironella, Meritxell|Alemany, Ramon|Fillat, Cristina | ||||||||||
| PMID: | 30341009 | ||||||||||