Primary Site >> Stomach Cancer

Gene >> MDM2

Journal: J Pathol. 1998 Sep;186(1):36-40.
Title: No evidence for functional inactivation of wild-type p53 protein by MDM2 overexpression in gastric carcinogenesis.
Author: Blok, P|Craanen, M E|Dekker, W|Offerhaus, G J|Tytgat, G N
PMID: 9875138
Journal: Am J Clin Pathol. 1999 Feb;111(2):241-7.
Title: Molecular alterations in early gastric carcinomas. No apparent correlation with Helicobacter pylori status.
Author: Blok, P|Craanen, M E|Offerhaus, G J|Dekker, W|Kuipers, E J|Meuwissen, S G|Tytgat, G N
PMID: 9930147
Journal: Pathol Res Pract. 1999;195(12):815-20.
Title: P53-protein accumulation and MDM2-protein overexpression in gastric carcinomas. No apparent correlation with survival.
Author: Kasper, H U|Schneider-Stock, R|Mellin, W|Gunther, T|Roessner, A
PMID: 10631716
Journal: Mod Pathol. 2000 Jun;13(6):621-6.
Title: Mdm2 gene amplification in gastric cancer correlation with expression of Mdm2 protein and p53 alterations.
Author: Gunther, T|Schneider-Stock, R|Hackel, C|Kasper, H U|Pross, M|Hackelsberger, A|Lippert, H|Roessner, A
PMID: 10874665
Journal: Rev Med Chil. 2000 Feb;128(2):127-36.
Title: [Gastric cancer and tumor growth regulation. Study of cell proliferation markers and protein complex p53/p21WAF1/CIP1/mdm-2].
Author: Villaseca, M|Araya, J C|Roa, I|Roa, J C
PMID: 10962880
Journal: Int J Oncol. 2003 Jun;22(6):1369-74.
Title: MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 12739007
Journal: J Pathol. 2003 Nov;201(3):439-50.
Title: Alterations of chromosomal copy number during progression of diffuse-type gastric carcinomas: metaphase- and array-based comparative genomic hybridization analyses of multiple samples from individual tumours.
Author: Peng, Dun-Fa|Sugihara, Hiroyuki|Mukaisho, Ken-ichi|Tsubosa, Yasuhiro|Hattori, Takanori
PMID: 14595756
Journal: Ai Zheng. 2004 Jan;23(1):36-9.
Title: [Relationship between gastric cancer and gene amplification of p14 and mdm2].
Author: Sun, Li-Ping|Jiang, Nai-Jia|Fu, Wei|Xue, Yi-Xue|Zhao, Yi-Song
PMID: 14720371
Journal: Nihon Rinsho. 2004 Jul;62(7):1377-86.
Title: [The mechanisms of gastric cancer development produced by the combination of Helicobacter pylori with Sterigmatocystin, a mycotoxin].
Author: Misumi, Junichi
PMID: 15283159
Journal: J Gastroenterol Hepatol. 2005 Jun;20(6):941-6.
Title: Eradication of Helicobacter pylori reduced the immunohistochemical detection of p53 and MDM2 in gastric mucosa.
Author: Kodama, Masaaki|Fujioka, Toshio|Murakami, Kazunari|Okimoto, Tadayoshi|Sato, Ryugo|Watanabe, Koichiro|Nasu, Masaru
PMID: 15946145
Journal: J Clin Oncol. 2006 Sep 20;24(27):4434-40.
Title: MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.
Author: Ohmiya, Naoki|Taguchi, Ayumu|Mabuchi, Nobuyuki|Itoh, Akihiro|Hirooka, Yoshiki|Niwa, Yasumasa|Goto, Hidemi
PMID: 16983111
Journal: J Huazhong Univ Sci Technolog Med Sci. 2006;26(6):674-7.
Title: Comparative study on cancer cell apoptosis between gastric and intestinal-type human gastric carcinoma.
Author: Liu, Limin|Lu, Shengjun|Chen, Qingshan|Xiao, Heping|Mao, Yongrong
PMID: 17357486
Journal: Carcinogenesis. 2007 Sep;28(9):2013-8. Epub 2007 Aug 8.
Title: Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.
Author: Yamada, Hidetaka|Shinmura, Kazuya|Okudela, Koji|Goto, Masanori|Suzuki, Masaya|Kuriki, Ken|Tsuneyoshi, Toshihiro|Sugimura, Haruhiko
PMID: 17690113
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Jul;30(7):494-7.
Title: [Impact of PI3K /Akt /mdm2 signaling pathway on the sensitivity of gastric cancer cell line SGC7901 to doxorubicin].
Author: Ai, Yao-Wei|Yu, Hong-Gang|Yu, Jie-Ping|Yang, Yan|Li, Huan|Hu, Xiao-Wen|Luo, He-Sheng
PMID: 19062713
Journal: Neoplasma. 2008;55(3):256-60.
Title: No association of MDM2 T309G polymorphism with susceptibility to Korean gastric cancer patients.
Author: Cho, Y G|Choi, B J|Song, J H|Kim, C J|Cao, Z|Nam, S W|Lee, J Y|Park, W S
PMID: 18348658
Journal: J Clin Biochem Nutr. 2009 Mar;44(2):196-202.
Title: The Expression of Murine Double Minute 2 (MDM2) on Helicobacter pylori-Infected Intestinal Metaplasia and Gastric Cancer.
Author: Nakajima, Noriko|Ito, Yoko|Yokoyama, Kiyoshi|Uno, Akitake|Kinukawa, Noriko|Nemoto, Norimichi|Moriyama, Mitsuhiko
PMID: 19308274
Journal: Food Chem Toxicol. 2009 Aug;47(8):2013-21.
Title: Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells.
Author: Lu, Te-Ling|Huang, Guan-Jhong|Lu, Te-Jung|Wu, Jin-Bin|Wu, Chieh-Hsi|Yang, Tung-Chuan|Iizuka, Akira|Chen, Yuh-Fung
PMID: 19477214
Journal: Oncol Rep. 2009 Jul;22(1):73-80.
Title: The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
Author: Chen, Xi|Zhang, Mu|Liu, Lian-Xin
PMID: 19513507
Journal: Helicobacter. 2009 Oct;14(5):114-9.
Title: Interaction of Helicobacter pylori with genetic variants in the MDM2 promoter, is associated with gastric cancer susceptibility in Chinese patients.
Author: Wang, Xiaoyong|Yang, Jing|Ho, Bo|Yang, Yang|Huang, Zuhu|Zhang, Zhihong|Zhang, Guoxin
PMID: 19751436
Journal: J Gene Med. 2010 Feb;12(2):147-56.
Title: Inhibition of the p53-MDM2 interaction by adenovirus delivery of ribosomal protein L23 stabilizes p53 and induces cell cycle arrest and apoptosis in gastric cancer.
Author: Zhang, Yafei|Shi, Yongquan|Li, Xiaohua|Du, Wenqi|Luo, Guanhong|Gou, Yawen|Wang, Xin|Guo, Xuegang|Liu, Jie|Ding, Jie|Wu, Kaichun|Fan, Daiming
PMID: 20020415
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2010 Feb;27(1):60-5.
Title: [Analysis of the P53 transcriptional activity in gastric cancer].
Author: Zhu, Yajie|Qiu, Meng|Zhou, Jitao|Liu, Ming|Liu, Surui|Huang, Juan|Bi, Feng
PMID: 20140870
Journal: Pathologe. 2010 May;31(3):199-204.
Title: [Atypical lipomatous tumors of the stomach. Clinical, morphological and molecular findings].
Author: Kuhnen, C|Mentzel, T|Haarmann, W|Schwegler, U|Sciot, R|Debiec-Rychter, M
PMID: 20221763
Journal: J Cell Biochem. 2010 Sep 1;111(1):218-28.
Title: PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
Author: Zheng, Tongsen|Meng, Xianzhi|Wang, Jiabei|Chen, Xi|Yin, Dalong|Liang, Yingjian|Song, Xuan|Pan, Shangha|Jiang, Hongchi|Liu, Lianxin
PMID: 20506484
Journal: Gastroenterology. 2010 Oct;139(4):1333-43.
Title: Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells.
Author: Wei, Jinxiong|Nagy, Toni A|Vilgelm, Anna|Zaika, Elena|Ogden, Seth R|Romero-Gallo, Judith|Piazuelo, Maria B|Correa, Pelayo|Washington, Mary K|El-Rifai, Wael|Peek, Richard M|Zaika, Alexander
PMID: 20547161
Journal: J Clin Invest. 2010 Dec;120(12):4493-506.
Title: Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
Author: Jung, Cho-Rok|Lim, Jung Hwa|Choi, Yoonjung|Kim, Dae-Ghon|Kang, Koo Jeong|Noh, Seung-Moo|Im, Dong-Soo
PMID: 21060154
Journal: Cancer Lett. 2011 Mar 1;302(1):69-75.
Title: Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosis.
Author: Xiao, Xiu-ying|Hao, Miao|Yang, Xin-ying|Ba, Qian|Li, Mian|Ni, Shu-juan|Wang, Li-Sha|Du, Xiang
PMID: 21216524
Journal: Oncol Lett. 2011 Jul;2(4):707-712.
Title: Expression and significance of p53 and mdm2 in atypical intestinal metaplasia and gastric carcinoma.
Author: Wang, Lin|Zhang, Xiao-Ying|Xu, Ling|Liu, Wen-Jun|Zhang, Juan|Zhang, Jian-Ping
PMID: 22848253
Journal: BMC Med Genomics. 2011 Dec 2;4:82.
Title: Identification of DNA methylation changes associated with human gastric cancer.
Author: Park, Jung-Hoon|Park, Jinah|Choi, Jung Kyoon|Lyu, Jaemyun|Bae, Min-Gyun|Lee, Young-Gun|Bae, Jae-Bum|Park, Dong Yoon|Yang, Han-Kwang|Kim, Tae-You|Kim, Young-Joon
PMID: 22133303
Journal: Environ Health Prev Med. 2011 Jul;16(4):224-31.
Title: Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils.
Author: Kusunoki, Masahiro|Misumi, Junichi|Shimada, Tatsuo|Aoki, Kazuo|Matsuo, Noritaka|Sumiyoshi, Hideaki|Yamaguchi, Takeshi|Yoshioka, Hidekatsu
PMID: 21431817
Journal: Cancer Sci. 2011 Mar;102(3):605-13.
Title: Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells.
Author: Endo, Shinji|Yamato, Kenji|Hirai, Sachiko|Moriwaki, Toshikazu|Fukuda, Kuniaki|Suzuki, Hideo|Abei, Masato|Nakagawa, Ichiro|Hyodo, Ichinosuke
PMID: 21205074
Journal: Nat Commun. 2012 May 15;3:836.
Title: A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.
Author: Chau, Jenny Fung Ling|Jia, Deyong|Wang, Zhongfeng|Liu, Zhi|Hu, Yuanyu|Zhang, Xin|Jia, Hao|Lai, Keng Po|Leong, Wai Fook|Au, Bi Jin|Mishina, Yuji|Chen, Ye-Guang|Biondi, Christine|Robertson, Elizabeth|Xie, Dong|Liu, Huijuan|He, Lin|Wang, Xueying|Yu, Qiang|Li
PMID: 22588298
Journal: J Biomed Sci. 2012 Sep 10;19:82.
Title: Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways.
Author: Choi, Hyeong Sim|Seo, Hye-Sook|Kim, Ji Hye|Um, Jae-Young|Shin, Yong Cheol|Ko, Seong-Gyu
PMID: 22963678
Journal: PLoS One. 2012;7(10):e41693.
Title: MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer.
Author: Wang, Ying|Zheng, Xiushan|Zhang, Zhiyong|Zhou, Jinfeng|Zhao, Guohong|Yang, Jianjun|Xia, Limin|Wang, Rui|Cai, Xiqiang|Hu, Hao|Zhu, Cailin|Nie, Yongzhan|Wu, Kaichun|Zhang, Dexin|Fan, Daiming
PMID: 23144691
Journal: Gastroenterol Hepatol Bed Bench. 2012 Winter;5(1):60-3.
Title: Giant gastric lipoma mimicking well-differentiated liposarcoma.
Author: Hamdane, Mohamed Moncef|Brahim, Ehsen Ben|Salah, Meriam Belhaj|Haouas, Nooman|Bouhafa, Ahmed|Chedly-Debbiche, Achraf
PMID: 24834200
Journal: Clin Res Hepatol Gastroenterol. 2012 Jun;36(3):235-43.
Title: Expression of p53-MDM2 feedback loop related proteins in different gastric pathologies in relation to Helicobacter pylori infection: implications in gastric carcinogenesis.
Author: Yang, Zhen|Shu, Xu|Chen, Lian|Chen, Jiang|Xie, Yong|Lu, Nong-Hua
PMID: 22306053
Journal: Asian Pac J Cancer Prev. 2013;14(3):1925-9.
Title: Association between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.
Author: Tian, Xin|Tian, Ye|Ma, Ping|Sui, Cheng-Guang|Meng, Fan-Dong|Li, Yan|Fu, Li-Ye|Jiang, Tao|Wang, Yang|Ji, Fu-Jian|Fang, Xue-Dong|Jiang, You-Hong
PMID: 23679294
Journal: Eur J Pharmacol. 2013 Nov 15;720(1-3):84-97.
Title: HZ08 reverse the aneuploidy-induced cisplatin-resistance in Gastric cancer by modulating the p53 pathway.
Author: Tang, Xuzhen|Hu, Gang|Xu, Chunhua|Ouyang, Kedong|Fang, Weirong|Huang, Wenlong|Zhang, Jingjing|Li, Fu|Wang, Ke|Qin, Xiaoran|Li, Yunman
PMID: 24183976
Journal: Int J Surg Pathol. 2013 Oct;21(5):455-75.
Title: The utility of immunohistochemistry for providing genetic information on tumors.
Author: Chan, John K C|Ip, Yiu-Tung|Cheuk, Wah
PMID: 24065374
Journal: Br J Cancer. 2013 Oct 15;109(8):2199-206.
Title: PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression.
Author: Uchi, R|Kogo, R|Kawahara, K|Sudo, T|Yokobori, T|Eguchi, H|Sugimachi, K|Maehama, T|Mori, M|Suzuki, A|Komune, S|Mimori, K
PMID: 24045667
Journal: Genet Test Mol Biomarkers. 2013 Nov;17(11):794-8.
Title: Helicobacter pylori infection and MDM2 SNP309 association with gastric cancer susceptibility.
Author: Moradi, Mohammad Taher|Salehi, Zivar|Asl, Saba Fakhrieh|Aminian, Keyvan|Hashtchin, Anna Rafiei
PMID: 24010568
Journal: Oncol Rep. 2013 Oct;30(4):1989-95.
Title: Co-transduction of ribosomal protein L23 enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in human gastric cancer.
Author: Zhang, Ya-Fei|Zhang, Bi-Cheng|Zhang, An-Ran|Wu, Ting-Ting|Liu, Jian|Yu, Li-Fang|Wang, Wei-Xing|Gao, Jian-Fei|Fang, Dian-Chun|Rao, Zhi-Guo
PMID: 23933826
Journal: Br J Cancer. 2013 Jun 25;108(12):2557-64.
Title: Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer.
Author: Zhao, J|Liang, Q|Cheung, K-F|Kang, W|Dong, Y|Lung, R W-M|Tong, J H-M|To, K-F|Sung, J J Y|Yu, J
PMID: 23722468
Journal: BMC Cancer. 2013 Mar 18;13:126.
Title: A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients.
Author: Pan, Xiaolin|Li, Yuqin|Feng, Jin|Wang, Xiaoyong|Hao, Bo|Shi, Ruihua|Zhang, Guoxin
PMID: 23506213
Journal: PLoS One. 2013;8(2):e56918.
Title: MDM2 SNP309 rs2279744 polymorphism and gastric cancer risk: a meta-analysis.
Author: Ma, Yong|Bian, Jianmin|Cao, Hongyong
PMID: 23451111
Journal: Cancer Chemother Pharmacol. 2013 Apr;71(4):1073-82.
Title: Effect of TP53 codon 72 and MDM2 SNP309 polymorphisms on survival of gastric cancer among patients who receiving 5-fluorouracil-based postoperative adjuvant chemotherapy.
Author: Wang, Shizhi|Chen, Lulu|Zhao, Qinghong|Rong, Huan|Wang, Meilin|Gong, Weida|Zhou, Jianwei|Wu, Dongmei|Zhang, Zhengdong
PMID: 23423487
Journal: Cancer Sci. 2013 May;104(5):590-8.
Title: MDM2 is a useful prognostic biomarker for resectable gastric cancer.
Author: Ye, Yang|Li, Xuan|Yang, Jingjing|Miao, Shuhan|Wang, Shouyu|Chen, Yansu|Xia, Xiaowei|Wu, Xuming|Zhang, Jianbing|Zhou, Yan|He, Song|Tan, Yongfei|Qiang, Fulin|Li, Gang|Roe, Oluf Dimitri|Zhou, Jianwei
PMID: 23347235
Journal: Eur J Cancer. 2013 May;49(8):2010-21.
Title: miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation.
Author: Wang, Mei|Gu, Hongbing|Qian, Hui|Zhu, Wei|Zhao, Chonghui|Zhang, Xu|Tao, Yang|Zhang, Ling|Xu, Wenrong
PMID: 23333058
Journal: Asian Pac J Cancer Prev. 2014;15(17):7413-7.
Title: Effects of p53 codon 72 and MDM2 SNP309 polymorphisms on gastric cancer risk among the Iranian population.
Author: Moradi, Mohammad-Taher|Salehi, Zivar|Aminian, Keyvan|Yazdanbod, Abbas
PMID: 25227851
Journal: Med Oncol. 2014 Nov;31(11):270.
Title: Triptolide induces apoptosis of gastric cancer cells via inhibiting the overexpression of MDM2.
Author: Wang, Bo-Yong|Cao, Jun|Chen, Ji-Wei|Liu, Quan-Yan
PMID: 25280518
Journal: PLoS One. 2014 Aug 19;9(8):e104510.
Title: MicroRNA-410 suppresses migration and invasion by targeting MDM2 in gastric cancer.
Author: Shen, Jianjun|Niu, Weina|Zhou, Ming|Zhang, Hongbo|Ma, Jun|Wang, Ling|Zhang, Hongyan
PMID: 25136862
Journal: Oncotarget. 2014 Dec 15;5(23):12016-26.
Title: Role of p53 in the progression of gastric cancer.
Author: Busuttil, Rita A|Zapparoli, Giada V|Haupt, Sue|Fennell, Christina|Wong, Stephen Q|Pang, Jia-Min B|Takeno, Elena A|Mitchell, Catherine|Di Costanzo, Natasha|Fox, Stephen|Haupt, Ygal|Dobrovic, Alexander|Boussioutas, Alex
PMID: 25427447
Journal: Cell Cycle. 2014;13(18):2962-74.
Title: Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
Author: Lv, Hongjun|Liu, Rui|Fu, Jiao|Yang, Qi|Shi, Jing|Chen, Pu|Ji, Meiju|Shi, Bingyin|Hou, Peng
PMID: 25486483
Journal: Asian Pac J Cancer Prev. 2014 Jan;14(11):6649-51.
Title: Meta-analysis of the MDM2 T309G polymorphism and gastric cancer risk.
Author: Song, Bo|Duan, Zhong-Yu|Zhong, Yun-Hua|Lei, Na|Yang, Yu-Qing|Luo, Kai-Yuan
PMID: 24377582
Journal: Genome Biol. 2014 Apr 1;15(4):R55.
Title: Genomic profile analysis of diffuse-type gastric cancers.
Author: Lee, Yeon-Su|Cho, Yun Sung|Lee, Geon Kook|Lee, Sunghoon|Kim, Young-Woo|Jho, Sungwoong|Kim, Hak-Min|Hong, Seung-Hyun|Hwang, Jung-Ah|Kim, Sook-young|Hong, Dongwan|Choi, Il Ju|Kim, Byung Chul|Kim, Byoung-Chul|Kim, Chul Hong|Choi, Hansol|Kim, Youngju|Kim, Kyu
PMID: 24690483
Journal: J Int Med Res. 2014 Oct;42(5):1065-76.
Title: MDM2 oncogene, E3 ubiquitin protein ligase T309G polymorphism and risk of oesophageal or gastric cancer: meta-analysis of 15 studies.
Author: Shen, Wei|Hu, Ping|Cao, Jia-qing|Liu, Xiu-xia|Shao, Jiang-hua
PMID: 25070969
Journal: Clin Cancer Res. 2014 Jan 1;20(1):76-86.
Title: HDM2 regulation by AURKA promotes cell survival in gastric cancer.
Author: Sehdev, Vikas|Katsha, Ahmed|Arras, Janet|Peng, Dunfa|Soutto, Mohammed|Ecsedy, Jeffrey|Zaika, Alexander|Belkhiri, Abbes|El-Rifai, Wael
PMID: 24240108
Journal: Tumour Biol. 2014 Apr;35(4):3431-8.
Title: MDM2 SNP309 is an ethnicity-dependent risk factor for digestive tract cancers.
Author: Chen, Bo|Cao, Lei|Hu, Kong-Wang|Zhang, Jia-Wei|Meng, Xiang-Ling|Xiong, Mao-Ming
PMID: 24338709
Journal: Biomed Rep. 2014 Jan;2(1):105-111.
Title: Meta-analysis of associations between MDM2 SNP309 polymorphism and gastric cancer risk.
Author: Chen, Weifeng|Wu, Qianlan|Ren, Hongbo
PMID: 24649079
Journal: Hum Pathol. 2014 Apr;45(4):725-34.
Title: Intratumoral heterogeneous amplification of ERBB2 and subclonal genetic diversity in gastric cancers revealed by multiple ligation-dependent probe amplification and fluorescence in situ hybridization.
Author: Tajiri, Ryosuke|Ooi, Akishi|Fujimura, Takashi|Dobashi, Yoh|Oyama, Takeru|Nakamura, Ritsuko|Ikeda, Hiroko
PMID: 24491355
Journal: Clin Cancer Res. 2015 Feb 1;21(3):661.
Title: Correction: HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer.
Author:
PMID: 25646184
Journal: Asian Pac J Cancer Prev. 2015;16(17):7781-4.
Title: Correlation between Patterns of Mdm2 SNIP 309 and Histopathological Severity of Helicobacter pylori Associated Gastritis in Thailand.
Author: Tongtawee, Taweesak|Dechsukhum, Chavaboon|Talabnin, Krajang|Leeanansaksiri, Wilairat|Kaewpitoon, Soraya|Kaewpitoon, Natthawut|Loyd, Ryan A|Matrakool, Likit|Panpimanmas, Sukij
PMID: 26625797
Journal: Asian Pac J Cancer Prev. 2015;16(16):7049-52.
Title: Genetic Polymorphism of MDM2 SNP309 in Patients with Helicobacter Pylori-Associated Gastritis.
Author: Tongtawee, Taweesak|Dechsukhum, Chavaboon|Leeanansaksiri, Wilairat|Kaewpitoon, Soraya|Kaewpitoon, Natthawut|Loyd, Ryan A|Matrakool, Likit|Panpimanmas, Sukij
PMID: 26514489
Journal: J Nanosci Nanotechnol. 2015 Jul;15(7):4815-28.
Title: Polymorphisms in NEIL-2, APE-1, CYP2E1 and MDM2 Genes are Independent Predictors of Gastric Cancer Risk in a Northern Jiangsu Population (China).
Author: Elingarami, Sauli|Liu, Hongna|Kalinjuma, Aneth Vedastus|Hu, Weiyue|Li, Song|He, Nongyue
PMID: 26373042
Journal: Int J Oncol. 2015 Nov;47(5):1725-34.
Title: Fra-1 is upregulated in gastric cancer tissues and affects the PI3K/Akt and p53 signaling pathway in gastric cancer.
Author: He, Junyu|Zhu, Guangchao|Gao, Lu|Chen, Pan|Long, Yuehua|Liao, Shan|Yi, Hong|Yi, Wei|Pei, Zhen|Wu, Minghua|Li, Xiaoling|Xiang, Juanjuan|Peng, Shuping|Ma, Jian|Zhou, Ming|Xiong, Wei|Zeng, Zhaoyang|Xiang, Bo|Tang, Ke|Cao, Li|Li, Guiyuan|Zhou, Yanhong
PMID: 26330014
Journal: Eur Rev Med Pharmacol Sci. 2015 Jul;19(13):2416-22.
Title: Role of Delta133p53 in Tumor Necrosis Factor-induced survival of p53 functions in MKN45 gastric cancer cell line.
Author: Shang, Z-M|Tang, J-D|Jiang, Q-Q|Guo, A|Zhang, N|Gao, Z-X|Ji, W-S
PMID: 26214777
Journal: Mod Pathol. 2015 Jun;28(6):861-71.
Title: Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization.
Author: Ooi, Akishi|Oyama, Takeru|Nakamura, Ritsuko|Tajiri, Ryosuke|Ikeda, Hiroko|Fushida, Sachio|Nakamura, Hiroyuki|Dobashi, Yoh
PMID: 25743022
Journal: Oncotarget. 2015 Jan 30;6(3):1531-43.
Title: Helicobacter pylori bacteria alter the p53 stress response via ERK-HDM2 pathway.
Author: Bhardwaj, Vikas|Noto, Jennifer M|Wei, Jinxiong|Andl, Claudia|El-Rifai, Wael|Peek, Richard M|Zaika, Alexander I
PMID: 25605238
Journal: Drug Des Devel Ther. 2014 Dec 16;9:79-92.
Title: Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Author: Zhang, Lian|Tian, Wei|Kim, Sungkyoung|Ding, Wenping|Tong, Yingying|Chen, Siyu
PMID: 25565771
Journal: Med Oncol. 2015 Jan;32(1):401.
Title: Genetic association of single nucleotide polymorphisms in P53 pathway with gastric cancer risk in a Chinese Han population.
Author: Wu, Guo-Cong|Zhang, Zhong-Tao
PMID: 25479941
Journal: J Pathol. 2015 Mar;235(4):656-67.
Title: UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
Author: Zhang, Xiao-Wei|Wang, Xiao-Feng|Ni, Su-Jie|Qin, Wei|Zhao, Li-Qin|Hua, Rui-Xi|Lu, You-Wei|Li, Jin|Dimri, Goberdhan P|Guo, Wei-Jian
PMID: 25382750
Journal: Int J Cancer. 2015 May 1;136(9):2120-31.
Title: A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharide.
Author: Ye, Feng|Tang, Chunli|Shi, Weijia|Qian, Juan|Xiao, Shuping|Gu, Min|Dang, Yini|Liu, Jianping|Chen, Yan|Shi, Ruihua|Zhang, Guoxin
PMID: 25307786
Journal: Gut. 2015 Jul;64(7):1040-8.
Title: Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner.
Author: Wei, Jinxiong|Noto, Jennifer M|Zaika, Elena|Romero-Gallo, Judith|Piazuelo, Maria Blanca|Schneider, Barbara|El-Rifai, Wael|Correa, Pelayo|Peek, Richard M|Zaika, Alexander I
PMID: 25080447
Journal: Oncotarget. 2016 Nov 8;7(45):72990-73002.
Title: Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
Author: Wang, Sai-Qi|Wang, Cong|Chang, Li-Ming|Zhou, Kai-Rui|Wang, Jun-Wei|Ke, Yu|Yang, Dong-Xiao|Shi, Hong-Ge|Wang, Ran|Shi, Xiao-Li|Ma, Li-Ying|Liu, Hong-Min
PMID: 27659528
Journal: Oncotarget. 2016 Oct 4;7(40):66276-66286.
Title: p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?
Author: Li, Nianshuang|Xie, Chuan|Lu, Nong-Hua
PMID: 27556187
Journal: Mol Med Rep. 2016 Sep;14(3):2657-64.
Title: MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and motility by directly targeting MDM2.
Author: Yan, Yu|Peng, Yong|Ou, Yangzhu|Jiang, Yugang
PMID: 27485527
Journal: Gastroenterol Res Pract. 2016;2016:9130602.
Title: Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand.
Author: Tongtawee, Taweesak|Kaewpitoon, Soraya|Kaewpitoon, Natthawut|Dechsukhum, Chavaboon|Leeanansaksiri, Wilairat|Loyd, Ryan A|Matrakool, Likit|Panpimanmas, Sukij
PMID: 27042174
Journal: Int J Oncol. 2016 Oct;49(4):1589-99.
Title: Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer.
Author: Zeng, Yang|Fu, Meng|Wu, Gang-Wei|Zhang, An-Zu|Chen, Jin-Ping|Lin, Hong-Yue|Fu, Yong-An|Jia, Jing|Cai, Zong-Da|Wu, Xiao-Jian|Lan, Ping
PMID: 27499479
Journal: Biomed Rep. 2017 Nov;7(5):469-473.
Title: Investigation of the association between the MDM2 T309G polymorphism and gastric cancer.
Author: Tas, Ayca|Atabey, Mustafa|Caglayan, Gulcin|Bostanci, Meric Emre|Sahin Bolukbasi, Serap|Topcu, Omer|Silig, Yavuz
PMID: 29181159
Journal: World J Gastroenterol. 2017 Dec 28;23(48):8533-8543.
Title: Analysis of 12 variants in the development of gastric and colorectal cancers.
Author: Cavalcante, Giovanna C|Amador, Marcos At|Ribeiro Dos Santos, Andre M|Carvalho, Darlen C|Andrade, Roberta B|Pereira, Esdras Eb|Fernandes, Marianne R|Costa, Danielle F|Santos, Ney Pc|Assumpcao, Paulo P|Ribeiro Dos Santos, Andrea|Santos, Sidney
PMID: 29358861
Journal: Oncotarget. 2017 Dec 4;8(67):111597-111607.
Title: LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)-Mdm2-P53-dependent cellular senescence.
Author: Wang, Haibin|Xu, Guoxing|Huang, Zhengjie|Li, Weizheng|Cai, Huali|Zhang, Yunda|Xiong, Disheng|Liu, Gang|Wang, Shengjie|Xue, Zengfu|Luo, Qi
PMID: 29340077
Journal: Oncotarget. 2017 May 19;8(42):71894-71910.
Title: Identification of a novel YAP-14-3-3zeta negative feedback loop in gastric cancer.
Author: Zhang, Bin|Gong, Aihua|Shi, Hui|Bie, Qingli|Liang, Zhaofeng|Wu, Peipei|Mao, Fei|Qian, Hui|Xu, Wenrong
PMID: 29069755
Journal: Mol Med Rep. 2017 Nov;16(5):7277-7286.
Title: CMIP is oncogenic in human gastric cancer cells.
Author: Zhang, Jianlin|Huang, Jin|Wang, Xingyu|Chen, Weidong|Tang, Qinqing|Fang, Maoyong|Qian, Yeben
PMID: 28944848
Journal: Mol Oncol. 2017 Aug;11(8):981-995.
Title: Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.
Author: Wang, Lihong|Arras, Janet|Katsha, Ahmed|Hamdan, Saif|Belkhiri, Abbes|Ecsedy, Jeffrey|El-Rifai, Wael
PMID: 28417568
Journal: Eur J Pharmacol. 2017 Mar 5;798:49-56.
Title: 12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis.
Author: Wang, Xu De|Sun, Yuan Yuan|Zhao, Chen|Qu, Fan Zhi|Zhao, Yu Qing
PMID: 28017829
Journal: Gut. 2017 Jan;66(1):31-42.
Title: hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation.
Author: Hu, Changjiang|Ni, Zhenghong|Li, Bo-Sheng|Yong, Xin|Yang, Xin|Zhang, Jian-Wei|Zhang, Dan|Qin, Yong|Jie, Meng-Meng|Dong, Hui|Li, Song|He, Fengtian|Yang, Shi-Ming
PMID: 26370108
Journal: J Biol Regul Homeost Agents. 2018 Sep-Oct;32(5):1185-1189.
Title: PIG3 suppresses gastric cancer proliferation by regulating p53- mediated apoptosis.
Author: Chu, Y|Li, D|Zhang, H|Ding, J|Xu, P|Qiu, X|Zhang, H
PMID: 30334411
Journal: Turk J Gastroenterol. 2018 Sep;29(5):555-560.
Title: Role of screening colonoscopy for colorectal tumors in Helicobacter pylori-related chronic gastritis with MDM2 SNP309 G/G homozygous: A prospective cross-sectional study in Thailand.
Author: Tongtawee, Taweesak|Simawaranon, Theeraya|Wattanawongdon, Wareporn
PMID: 30260777
Journal: Cancer Biol Ther. 2018 Sep 25:1-6.
Title: Double amplifications of CDK4 and MDM2 in a gastric inflammatory myofibroblastic tumor mimicking cancer with local invasion of the spleen and diaphragm.
Author: He, Jia|Zhao, Xinyi|Huang, Cheng|Zhou, Xiaoyun|You, Yan|Zhang, Lu|Lu, Chongmei|Yao, Fang|Li, Shanqing
PMID: 30252584
Journal: Oncoimmunology. 2018 Apr 18;7(8):e1452582.
Title: Using a panel of multiple tumor-associated antigens to enhance autoantibody detection for immunodiagnosis of gastric cancer.
Author: Wang, Shuaibing|Qin, Jiejie|Ye, Hua|Wang, Keyan|Shi, Jianxiang|Ma, Yan|Duan, Yitao|Song, Chunhua|Wang, Xiao|Dai, Liping|Wang, Kaijuan|Wang, Peng|Zhang, Jianying
PMID: 30221047
Journal: Environ Sci Pollut Res Int. 2018 Sep 12. pii: 10.1007/s11356-018-3080-1.
Title: Lifestyle chemical carcinogens associated with mutations in cell cycle regulatory genes increases the susceptibility to gastric cancer risk.
Author: Yadav, Ravi Prakash|Ghatak, Souvik|Chakraborty, Payel|Lalrohlui, Freda|Kannan, Ravi|Kumar, Rajeev|Pautu, Jeremy L|Zomingthanga, John|Chenkual, Saia|Muthukumaran, Rajendra|Senthil Kumar, Nachimuthu
PMID: 30209766
Journal: Biomed Pharmacother. 2018 Jan;97:1595-1602.
Title: Micro RNA-518 inhibits gastric cancer cell growth by inducing apoptosis via targeting MDM2.
Author: Feng, Changjun|Xian, Qingjie|Liu, Shuntao
PMID: 29793321
Journal: Int J Clin Oncol. 2018 Oct;23(5):867-876.
Title: The MDM2 rs937283 A > G variant significantly increases the risk of lung and gastric cancer in Chinese population.
Author: Chen, Bifeng|Wang, Jieling|Chen, Yucan|Gu, Xiuli|Feng, Xianhong
PMID: 29777315
Journal: J Exp Clin Cancer Res. 2018 May 2;37(1):97.
Title: A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma.
Author: Yi, Hanjie|Yan, Xianglei|Luo, Qiuyun|Yuan, Luping|Li, Baoxia|Pan, Wentao|Zhang, Lin|Chen, Haibo|Wang, Jing|Zhang, Yubin|Zhai, Yifan|Qiu, Miao-Zhen|Yang, Da-Jun
PMID: 29716622
Journal: Clin Sci (Lond). 2018 May 23;132(9):1003-1019.
Title: Prader-Willi region non-protein coding RNA 1 suppressed gastric cancer growth as a competing endogenous RNA of miR-425-5p.
Author: Chen, Zihao|Ju, Hongping|Yu, Shan|Zhao, Ting|Jing, Xiaojie|Li, Ping|Jia, Jing|Li, Nan|Tan, Bibo|Li, Yong
PMID: 29535266
Journal: Oncol Rep. 2018 Apr;39(4):1975-1983.
Title: Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway.
Author: Song, Jun|Ma, Sai-Jun|Luo, Jian-Hua|Zhang, Hui|Wang, Ri-Xiong|Liu, Hui|Li, Li|Zhang, Zhi-Guang|Zhou, Rui-Xiang
PMID: 29484412
Journal: Oncotarget. 2017 Dec 11;9(5):5993-6006.
Title: Inhibition of IAP's and activation of p53 leads to caspase-dependent apoptosis in gastric cancer cells treated with Scutellarein.
Author: Gowda Saralamma, Venu Venkatarame|Lee, Ho Jeong|Raha, Suchismita|Lee, Won Sup|Kim, Eun Hee|Lee, Sang Joon|Heo, Jeong Doo|Won, Chungkil|Kang, Chang Keun|Kim, Gon Sup
PMID: 29464049
Journal: Mol Carcinog. 2018 Jun;57(6):722-734.
Title: HOXA13 contributes to gastric carcinogenesis through DHRS2 interacting with MDM2 and confers 5-FU resistance by a p53-dependent pathway.
Author: Han, Yang|Song, Chenlong|Wang, Jianying|Tang, Huamei|Peng, Zhihai|Lu, Su
PMID: 29436749
Journal: Pathologe. 2018 Mar;39(2):186-190.
Title: [Spindle-cell osteosclerotic bone lesion with MDM2 amplification].
Author: Mogler, C|Boxberg, M|Knebel, C|Weichert, W|Wortler, K|Specht, K
PMID: 29209796