Literatures

Primary Site >> Colorectal Cancer

Gene >> MDM2

1.
Journal:	Clin Mol Pathol. 1995 Feb;48(1):M12-6.
Title:	Immunohistochemically detectable p53 and mdm-2 oncoprotein expression in colorectal carcinoma: prognostic significance.
Author:	Ofner, D\|Maier, H\|Riedmann, B\|Holzberger, P\|Nogler, M\|Totsch, M\|Bankfalvi, A\|Winde, G\|Bocker, W\|Schmid, K W
PMID:	16695968

2.
Journal:	Cancer Res. 1996 Feb 15;56(4):840-7.
Title:	An abnormality in the p53 pathway following gamma-irradiation in many wild-type p53 human melanoma lines.
Author:	Bae, I\|Smith, M L\|Sheikh, M S\|Zhan, Q\|Scudiero, D A\|Friend, S H\|O'Connor, P M\|Fornace, A J Jr
PMID:	8631022

3.
Journal:	Oncogene. 1996 May 16;12(10):2057-67.
Title:	Acute and delayed apoptosis induced by thymidine deprivation correlates with expression of p53 and p53-regulated genes in colon carcinoma cells.
Author:	Harwood, F G\|Frazier, M W\|Krajewski, S\|Reed, J C\|Houghton, J A
PMID:	8668331

4.
Journal:	Int J Immunopharmacol. 1997 Sep-Oct;19(9-10):481-5.
Title:	Biomarkers for predicting response to regional chemo-immunotherapy in liver metastases from colorectal carcinoma.
Author:	Zaloudik, J\|Vagunda, V\|Drahokoupilova, M\|Janakova, L\|Talac, R\|Kalabis, J\|Sheard, M
PMID:	9637342

5.
Journal:	Semin Surg Oncol. 1998 Jan-Feb;14(1):3-12.
Title:	Molecular changes during the genesis of human gliomas.
Author:	Sehgal, A
PMID:	9407626

6.
Journal:	Mol Pathol. 1998 Feb;51(1):26-9.
Title:	Expression of mdm2 and p53 in epithelial neoplasms of the colorectum.
Author:	Hao, X P\|Gunther, T\|Roessner, A\|Price, A B\|Talbot, I C
PMID:	9624416

7.
Journal:	EMBO J. 1999 Jun 1;18(11):3054-63.
Title:	Excess beta-catenin promotes accumulation of transcriptionally active p53.
Author:	Damalas, A\|Ben-Ze'ev, A\|Simcha, I\|Shtutman, M\|Leal, J F\|Zhurinsky, J\|Geiger, B\|Oren, M
PMID:	10357817

8.
Journal:	Histopathology. 1999 Oct;35(4):360-7.
Title:	bcl-2 protein expression is associated with better prognosis in colorectal cancer.
Author:	Leahy, D T\|Mulcahy, H E\|O'Donoghue, D P\|Parfrey, N A
PMID:	10564391

9.
Journal:	J Gastrointest Surg. 2000 Jan-Feb;4(1):109-14.
Title:	MDM2/p53 protein expression in the development of colorectal adenocarcinoma.
Author:	Abdel-Fattah, G\|Yoffe, B\|Krishnan, B\|Khaoustov, V\|Itani, K
PMID:	10631371

10.
Journal:	Cancer Res. 2000 Jan 1;60(1):129-33.
Title:	Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.
Author:	Esteller, M\|Tortola, S\|Toyota, M\|Capella, G\|Peinado, M A\|Baylin, S B\|Herman, J G
PMID:	10646864

11.
Journal:	J Pathol. 2000 Mar;190(4):450-6.
Title:	Staining patterns of p53 immunohistochemistry and their biological significance in colorectal cancer.
Author:	Kaserer, K\|Schmaus, J\|Bethge, U\|Migschitz, B\|Fasching, S\|Walch, A\|Herbst, F\|Teleky, B\|Wrba, F
PMID:	10699994

12.
Journal:	J Natl Cancer Inst. 2000 Apr 19;92(8):636-41.
Title:	Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells.
Author:	Yang, C T\|You, L\|Yeh, C C\|Chang, J W\|Zhang, F\|McCormick, F\|Jablons, D M
PMID:	10772681

13.
Journal:	Virchows Arch. 2000 Sep;437(3):241-7.
Title:	p53 gene status and expression of p53, mdm2, and p21Waf1/Cip1 proteins in colorectal cancer.
Author:	Veloso, M\|Wrba, F\|Kaserer, K\|Heinze, G\|Magalhaes, A\|Herbst, F\|Teleky, B
PMID:	11037343

14.
Journal:	Int J Cancer. 2000 Dec 1;88(5):804-9.
Title:	A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer.
Author:	Tortora, G\|Caputo, R\|Damiano, V\|Bianco, R\|Chen, J\|Agrawal, S\|Bianco, A R\|Ciardiello, F
PMID:	11072252

15.
Journal:	Rev Physiol Biochem Pharmacol. 2001;142:1-96.
Title:	Modulation of protein kinase C in antitumor treatment.
Author:	Hofmann, J
PMID:	11190577

16.
Journal:	Lab Invest. 2001 Feb;81(2):217-29.
Title:	Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer.
Author:	Burri, N\|Shaw, P\|Bouzourene, H\|Sordat, I\|Sordat, B\|Gillet, M\|Schorderet, D\|Bosman, F T\|Chaubert, P
PMID:	11232644

17.
Journal:	Cancer Res. 2001 Apr 1;61(7):2816-21.
Title:	p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Author:	Esteller, M\|Cordon-Cardo, C\|Corn, P G\|Meltzer, S J\|Pohar, K S\|Watkins, D N\|Capella, G\|Peinado, M A\|Matias-Guiu, X\|Prat, J\|Baylin, S B\|Herman, J G
PMID:	11306450

18.
Journal:	Cancer Lett. 2001 May 26;166(2):215-21.
Title:	Cell differentiation and chemotherapy influence p53 and Mdm2 immunoreactivity in human HT29 colon cancer cells grown in scid mice.
Author:	Schumacher, U\|Adam, E\|Feldhaus, S\|Katoh, M\|Lane, D P
PMID:	11311495

19.
Journal:	Virchows Arch. 2001 Jun;438(6):539-51.
Title:	Serous tumors of low malignant potential of the ovary-molecular pathology: part 2.
Author:	Hauptmann, S\|Dietel, M
PMID:	11469685

20.
Journal:	J Pathol. 2001 Aug;194(4):436-43.
Title:	Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival.
Author:	Elkablawy, M A\|Maxwell, P\|Williamson, K\|Anderson, N\|Hamilton, P W
PMID:	11523051

21.
Journal:	Int J Oncol. 2002 Apr;20(4):745-52.
Title:	Antisense anti-MDM2 mixed-backbone oligonucleotides enhance therapeutic efficacy of topoisomerase I inhibitor irinotecan in nude mice bearing human cancer xenografts: In vivo activity and mechanisms.
Author:	Wang, Hui\|Wang, Shuyi\|Nan, Li\|Yu, Dong\|Agrawal, Sudhir\|Zhang, Ruiwen
PMID:	11894120

22.
Journal:	Oncology. 2002;62(3):278-85.
Title:	mdm2-p53 Interaction: lack of correlation with the response to 5-fluorouracil in advanced colorectal cancer.
Author:	Paradiso, A\|Ranieri, G\|Simone, G\|Silvestris, N\|Costa, A\|De Lena, M\|Leone, A\|Vallejo, C\|Lacava, J
PMID:	12065876

23.
Journal:	Oncogene. 2002 May 9;21(20):3207-12.
Title:	Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways.
Author:	Weber, H Oliver\|Samuel, Temesgen\|Rauch, Pia\|Funk, Jens Oliver
PMID:	12082636

24.
Journal:	Mol Med. 2002 Apr;8(4):185-99.
Title:	Anti-tumor efficacy of a novel antisense anti-MDM2 mixed-backbone oligonucleotide in human colon cancer models: p53-dependent and p53-independent mechanisms.
Author:	Wang, Hui\|Nan, Li\|Yu, Dong\|Lindsey, J Russell\|Agrawal, Sudhir\|Zhang, Ruiwen
PMID:	12149568

25.
Journal:	J Biol Chem. 2002 Oct 4;277(40):37949-54. Epub 2002 Jul 31.
Title:	Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
Author:	Javelaud, Delphine\|Besancon, Francoise
PMID:	12151395

26.
Journal:	Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55.
Title:	The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein.
Author:	Takimoto, Rishu\|Wang, Wenge\|Dicker, David T\|Rastinejad, Farzan\|Lyssikatos, Joseph\|el-Deiry, Wafik S
PMID:	12174820

27.
Journal:	Mol Cancer Ther. 2003 Feb;2(2):139-50.
Title:	Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway.
Author:	Alonso, Michelle\|Tamasdan, Cristina\|Miller, Douglas C\|Newcomb, Elizabeth W
PMID:	12589031

28.
Journal:	Int J Oncol. 2003 Nov;23(5):1269-75.
Title:	The early response of p53-dependent proteins during radiotherapy in human rectal carcinoma and in adjacent normal tissue.
Author:	Stift, A\|Prager, G\|Selzer, E\|Widder, J\|Kandioler, D\|Friedl, J\|Teleky, B\|Herbst, F\|Wrba, F\|Bergmann, M
PMID:	14532965

29.
Journal:	Cancer Biol Ther. 2003 Sep-Oct;2(5):572-8.
Title:	Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2.
Author:	Zhang, Wei\|Ramdas, Latha\|Shen, Weiping\|Song, Sonya W\|Hu, Limei\|Hamilton, Stanley R
PMID:	14614330

30.
Journal:	J Biol Chem. 2004 Feb 27;279(9):7598-605.
Title:	Regulation of p53 stability and function in HCT116 colon cancer cells.
Author:	Kaeser, Matthias D\|Pebernard, Stephanie\|Iggo, Richard D
PMID:	14665630

31.
Journal:	Int J Oncol. 2004 Apr;24(4):951-8.
Title:	Wild-type p53 gene transfer into mutated p53 HT29 cells improves sensitivity to photodynamic therapy via induction of apoptosis.
Author:	Barberi-Heyob, Muriel\|Vedrine, Pierre-Olivier\|Merlin, Jean-Louis\|Millon, Regine\|Abecassis, Joseph\|Poupon, Marie-France\|Guillemin, Francois
PMID:	15010835

32.
Journal:	Carcinogenesis. 2004 Aug;25(8):1315-25.
Title:	beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate.
Author:	Palozza, Paola\|Serini, Simona\|Di Nicuolo, Fiorella\|Boninsegna, Alma\|Torsello, Angela\|Maggiano, Nicola\|Ranelletti, Franco O\|Wolf, Federica I\|Calviello, Gabriella\|Cittadini, Achille
PMID:	15073048

33.
Journal:	Proc Natl Acad Sci U S A. 2004 May 11;101(19):7386-91. Epub 2004 Apr 27.
Title:	p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels.
Author:	Iyer, N Gopalakrishna\|Chin, Suet-Feung\|Ozdag, Hilal\|Daigo, Yataro\|Hu, De-En\|Cariati, Massimiliano\|Brindle, Kevin\|Aparicio, Samuel\|Caldas, Carlos
PMID:	15123817

34.
Journal:	Carcinogenesis. 2004 Nov;25(11):2207-16.
Title:	Altered vegetable intake affects pivotal carcinogenesis pathways in colon mucosa from adenoma patients and controls.
Author:	van Breda, Simone G J\|van Agen, Ebienus\|Engels, Leopold G J B\|Moonen, Edwin J C\|Kleinjans, Jos C S\|van Delft, Joost H M
PMID:	15271855

35.
Journal:	Int J Oncol. 2004 Oct;25(4):913-20.
Title:	Dysfunction of p53 pathway in human colorectal cancer: analysis of p53 gene mutation and the expression of the p53-associated factors p14ARF, p33ING1, p21WAF1 and MDM2.
Author:	Tachibana, Masatsugu\|Kawamata, Hitoshi\|Fujimori, Takahiro\|Omotehara, Fumie\|Horiuchi, Hideki\|Ohkura, Yasuo\|Igarashi, Seiji\|Kotake, Kenjiro\|Kubota, Keiichi
PMID:	15375540

36.
Journal:	Int J Radiat Oncol Biol Phys. 2004 Nov 15;60(4):1264-71.
Title:	Effect of pH on radiation-induced p53 expression.
Author:	Choi, Eun Kyung\|Roberts, Kenneth P\|Griffin, Robert J\|Han, Taehee\|Park, Heon-Jin\|Song, Chang Won\|Park, Heon Joo
PMID:	15519799

37.
Journal:	Cancer Res. 2005 Mar 1;65(5):1918-24.
Title:	Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors.
Author:	Carvajal, Daisy\|Tovar, Christian\|Yang, Hong\|Vu, Binh T\|Heimbrook, David C\|Vassilev, Lyubomir T
PMID:	15753391

38.
Journal:	Clin Cancer Res. 2005 Jun 1;11(11):4234-40.
Title:	High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
Author:	Ricciardiello, Luigi\|Ceccarelli, Claudio\|Angiolini, Graziella\|Pariali, Milena\|Chieco, Pasquale\|Paterini, Paola\|Biasco, Guido\|Martinelli, Giuseppe N\|Roda, Enrico\|Bazzoli, Franco
PMID:	15930362

39.
Journal:	Clin Cancer Res. 2005 Jun 15;11(12):4580-8.
Title:	Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells.
Author:	Ghosh, Jagadish C\|Altieri, Dario C
PMID:	15958644

40.
Journal:	J Med Genet. 2005 Sep;42(9):694-8.
Title:	The MDM2 promoter polymorphism SNP309T-->G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck.
Author:	Alhopuro, P\|Ylisaukko-Oja, S K\|Koskinen, W J\|Bono, P\|Arola, J\|Jarvinen, H J\|Mecklin, J-P\|Atula, T\|Kontio, R\|Makitie, A A\|Suominen, S\|Leivo, I\|Vahteristo, P\|Aaltonen, L-M\|Aaltonen, L A
PMID:	16141004

41.
Journal:	Mol Cancer Res. 2005 Sep;3(9):511-7.
Title:	Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.
Author:	Kim, Jong-Sik\|Baek, Seung Joon\|Bottone, Frank G Jr\|Sali, Tina\|Eling, Thomas E
PMID:	16179498

42.
Journal:	Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6840-4.
Title:	p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome.
Author:	Sotamaa, Kaisa\|Liyanarachchi, Sandya\|Mecklin, Jukka-Pekka\|Jarvinen, Heikki\|Aaltonen, Lauri A\|Peltomaki, Paivi\|de la Chapelle, Albert
PMID:	16203772

43.
Journal:	Pathol Res Pract. 2005;201(12):777-89. Epub 2005 Oct 26.
Title:	Differential expression of Janus kinase 3 (JAK3), matrix metalloproteinase 13 (MMP13), heat shock protein 60 (HSP60), and mouse double minute 2 (MDM2) in human colorectal cancer progression using human cancer cDNA microarrays.
Author:	Mori, Daisuke\|Nakafusa, Yuji\|Miyazaki, Kohji\|Tokunaga, Osamu
PMID:	16308103

44.
Journal:	Cancer Lett. 2006 Feb 28;233(2):232-9.
Title:	Expression of cyclooxygenase-2 in colorectal adenocarcinoma is associated with p53 accumulation and hdm2 overexpression.
Author:	Cressey, Ratchada\|Pimpa, Sarunya\|Tontrong, Waragorn\|Watananupong, Onusa\|Leartprasertsuke, Nirush
PMID:	15921850

45.
Journal:	Biochem Biophys Res Commun. 2006 Jan 6;339(1):71-8. Epub 2005 Nov 8.
Title:	Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin.
Author:	Yu, Yan\|Sun, Ping\|Sun, Li-chun\|Liu, Guo-yi\|Chen, Guo-hua\|Shang, Li-hua\|Wu, Hong-bo\|Hu, Jing\|Li, Yue\|Mao, Yin-ling\|Sui, Guang-jie\|Sun, Xi-wen
PMID:	16297858

46.
Journal:	J Natl Cancer Inst. 2006 Feb 15;98(4):285-8.
Title:	Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.
Author:	Menin, Chiara\|Scaini, Maria Chiara\|De Salvo, Gian Luca\|Biscuola, Martina\|Quaggio, Monica\|Esposito, Giovanni\|Belluco, Claudio\|Montagna, Marco\|Agata, Simona\|D'Andrea, Emma\|Nitti, Donato\|Amadori, Alberto\|Bertorelle, Roberta
PMID:	16478747

47.
Journal:	Mol Cell Biol. 2006 Mar;26(6):2360-72.
Title:	Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.
Author:	Paliwal, Seema\|Pande, Sandhya\|Kovi, Ramesh C\|Sharpless, Norman E\|Bardeesy, Nabeel\|Grossman, Steven R
PMID:	16508011

48.
Journal:	Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.
Title:	Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
Author:	Choi, Hee-Jung\|Chung, Tae-Wook\|Kang, Sung-Koo\|Lee, Young-Choon\|Ko, Jeong-Heon\|Kim, Jong-Guk\|Kim, Cheorl-Ho
PMID:	16574813

49.
Journal:	Surg Today. 2006;36(7):608-14.
Title:	cDNA array analysis for prediction of hepatic metastasis of colorectal carcinoma.
Author:	Takata, Osamu\|Kawamura, Yutaka J\|Konishi, Fumio\|Sasaki, Junichi\|Kai, Toshihiro\|Miyakura, Yasuyuki\|Nagai, Hideo\|Tsukamoto, Toshihiko
PMID:	16794795

50.
Journal:	Toxicol Appl Pharmacol. 2006 Oct 1;216(1):89-97.
Title:	Azidothymidine and cisplatin increase p14ARF expression in OVCAR-3 ovarian cancer cell line.
Author:	Vaskivuo, Liisa\|Rysa, Jaana\|Koivupera, Johanna\|Myllynen, Paivi\|Vaskivuo, Tommi\|Chvalova, Katerina\|Serpi, Raisa\|Savolainen, Eeva-Riitta\|Puistola, Ulla\|Vahakangas, Kirsi
PMID:	16797627

51.
Journal:	Biochem Pharmacol. 2006 Oct 16;72(8):981-91. Epub 2006 Sep 1.
Title:	Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors.
Author:	Aizu, Wataru\|Belinsky, Glenn S\|Flynn, Christopher\|Noonan, Emily J\|Boes, Colleen C\|Godman, Cassandra A\|Doshi, Bindi\|Nambiar, Prashant R\|Rosenberg, Daniel W\|Giardina, Charles
PMID:	16949053

52.
Journal:	J Med Genet. 2007 Jan;44(1):75-80. Epub 2006 Jul 6.
Title:	Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-SNP309 colorectal cancer cells.
Author:	Alazzouzi, Hafid\|Suriano, Gianpaolo\|Guerra, Angel\|Plaja, Alberto\|Espin, Eloi\|Armengol, Manel\|Alhopuro, Pia\|Velho, Sergia\|Shinomura, Yasuhisa\|Gonzalez-Aguilera, Juan Jose\|Yamamoto, Hiroyuki\|Aaltonen, Lauri A\|Moreno, Victor\|Capella, Gabriel\|Peinado, Miguel
PMID:	16825434

53.
Journal:	Int J Cancer. 2007 Feb 1;120(3):563-5.
Title:	MDM2 SNP309 T>G alone or in combination with the TP53 R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal cancer in HNPCC patients.
Author:	Talseth, Bente A\|Meldrum, Cliff\|Suchy, Janina\|Kurzawski, Grzegroz\|Lubinski, Jan\|Scott, Rodney J
PMID:	17096342

54.
Journal:	J Biol Chem. 2007 Jan 26;282(4):2466-72.
Title:	Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner.
Author:	Zawacka-Pankau, Joanna\|Issaeva, Natalia\|Hossain, Shakil\|Pramanik, Aladdin\|Selivanova, Galina\|Podhajska, Anna J
PMID:	17135250

55.
Journal:	J Cancer Res Clin Oncol. 2007 Oct;133(10):749-59. Epub 2007 May 25.
Title:	Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression.
Author:	Alldinger, I\|Schaefer, K L\|Goedde, D\|Ottaviano, L\|Dirksen, U\|Ranft, A\|Juergens, H\|Gabbert, H E\|Knoefel, W T\|Poremba, C
PMID:	17530287

56.
Journal:	Cell Cycle. 2007 Jun 15;6(12):1468-71. Epub 2007 Apr 12.
Title:	p21 (CDKN1A) is a negative regulator of p53 stability.
Author:	Broude, Eugenia V\|Demidenko, Zoya N\|Vivo, Claire\|Swift, Mari E\|Davis, Brian M\|Blagosklonny, Mikhail V\|Roninson, Igor B
PMID:	17585201

57.
Journal:	Carcinogenesis. 2007 Nov;28(11):2262-7.
Title:	MDM2 SNP309 and cancer risk: a combined analysis.
Author:	Wilkening, Stefan\|Bermejo, Justo Lorenzo\|Hemminki, Kari
PMID:	17827408

58.
Journal:	Mol Cell Proteomics. 2007 Dec;6(12):2150-64.
Title:	A proteomics analysis of cell signaling alterations in colorectal cancer.
Author:	Madoz-Gurpide, Juan\|Canamero, Marta\|Sanchez, Lydia\|Solano, Jose\|Alfonso, Patricia\|Casal, J Ignacio
PMID:	17848589

59.
Journal:	Int J Surg Pathol. 2007 Oct;15(4):335-45.
Title:	p53 and mdm2 expression in colorectal carcinoma: a correlative analysis with clinical staging and histological parameters.
Author:	Das, Prasenjit\|Vaiphei, Kim\|Jain, Deepali\|Wig, Jai Dev
PMID:	17913939

60.
Journal:	Mol Cancer Res. 2007 Nov;5(11):1133-45.
Title:	Cyclin-dependent kinase inhibitors sensitize tumor cells to nutlin-induced apoptosis: a potent drug combination.
Author:	Cheok, Chit Fang\|Dey, Anwesha\|Lane, David P
PMID:	18025259

61.
Journal:	Cancer Res. 2007 Dec 15;67(24):11779-88.
Title:	Hsp27 modulates p53 signaling and suppresses cellular senescence.
Author:	O'Callaghan-Sunol, Cornelia\|Gabai, Vladimir L\|Sherman, Michael Y
PMID:	18089808

62.
Journal:	Dig Dis Sci. 2008 Feb;53(2):451-60. Epub 2007 Jun 12.
Title:	Potential role of apoptosis and apoptotic regulatory proteins in colorectal neoplasia: correlations with clinico-pathological parameters and survival.
Author:	Tzouvala, Maria\|Lazaris, Andreas C\|Papatheodoridis, George V\|Kouvidou, Chariklia\|Papathomas, Thomas G\|Kavantzas, Nikos\|Elemenoglou, Ioannis\|Karamanolis, Demetrios G\|Agapitos, Emmanouil
PMID:	17562177

63.
Journal:	Mol Carcinog. 2008 Jan;47(1):9-21.
Title:	Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
Author:	Fenton, Jenifer I\|Lavigne, Jackie A\|Perkins, Susan N\|Liu, Huaitian\|Chandramouli, Gadisetti V R\|Shih, Joanna H\|Hord, Norman G\|Hursting, Stephen D
PMID:	17620308

64.
Journal:	Biochem Pharmacol. 2008 Feb 15;75(4):787-809.
Title:	Curcumin as "Curecumin": from kitchen to clinic.
Author:	Goel, Ajay\|Kunnumakkara, Ajaikumar B\|Aggarwal, Bharat B
PMID:	17900536

65.
Journal:	Dig Dis Sci. 2008 Aug;53(8):2183-8. Epub 2007 Dec 14.
Title:	Abberant crypt foci -- importance in colorectal carcinogenesis and expression of p53 and mdm2: a changing concept.
Author:	Das, Prasenjit\|Jain, Deepali\|Vaiphei, Kim\|Wig, J D
PMID:	18080767

66.
Journal:	Mol Cell Biol. 2008 Mar;28(6):1999-2010.
Title:	Regulation of MDMX expression by mitogenic signaling.
Author:	Gilkes, Daniele M\|Pan, Yu\|Coppola, Domenico\|Yeatman, Timothy\|Reuther, Gary W\|Chen, Jiandong
PMID:	18172009

67.
Journal:	Biochem Biophys Res Commun. 2008 May 2;369(2):554-60.
Title:	IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells.
Author:	Li, Ben Hui\|Yang, Xian Zi\|Li, Pin Dong\|Yuan, Qin\|Liu, Xiao Hong\|Yuan, Jia\|Zhang, Wen Jie
PMID:	18294957

68.
Journal:	Mol Cancer Res. 2008 Feb;6(2):205-11.
Title:	MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.
Author:	Forslund, Ann\|Zeng, Zhaoshi\|Qin, Li-Xuan\|Rosenberg, Shoshana\|Ndubuisi, MacKevin\|Pincas, Hanna\|Gerald, William\|Notterman, Daniel A\|Barany, Francis\|Paty, Philip B
PMID:	18314481

69.
Journal:	J Surg Oncol. 2008 Jun 1;97(7):621-5.
Title:	Genetic variants in germline TP53 and MDM2 SNP309 are not associated with early onset colorectal cancer.
Author:	Khan, Sajid A\|Idrees, Kamran\|Forslund, Ann\|Zeng, Zhaoshi\|Rosenberg, Shoshana\|Pincas, Hanna\|Barany, Francis\|Offit, Kenneth\|Laquaglia, Michael P\|Paty, Philip B
PMID:	18381604

70.
Journal:	Cell Cycle. 2008 May 1;7(9):1205-13. Epub 2008 Feb 11.
Title:	A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model.
Author:	Becker, Kerstin\|Marchenko, Natalia D\|Palacios, Gustavo\|Moll, Ute M
PMID:	18418047

71.
Journal:	J Cell Biochem. 2008 Aug 15;104(6):2228-40.
Title:	Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity.
Author:	Farmer, Tiffany E\|Williams, Christopher S\|Washington, M Kay\|Hiebert, Scott W
PMID:	18442038

72.
Journal:	Oncogene. 2008 Sep 11;27(40):5303-14.
Title:	E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
Author:	Kitagawa, M\|Aonuma, M\|Lee, S H\|Fukutake, S\|McCormick, F
PMID:	18521084

73.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1533-42.
Title:	Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer.
Author:	Shangary, Sanjeev\|Ding, Ke\|Qiu, Su\|Nikolovska-Coleska, Zaneta\|Bauer, Joshua A\|Liu, Meilan\|Wang, Guoping\|Lu, Yipin\|McEachern, Donna\|Bernard, Denzil\|Bradford, Carol R\|Carey, Thomas E\|Wang, Shaomeng
PMID:	18566224

74.
Journal:	Dis Colon Rectum. 2008 Sep;51(9):1395-402.
Title:	MDM2 mRNA expression in the p53 pathway may predict the potential of invasion and liver metastasis in colorectal cancer.
Author:	Kondo, Ito\|Iida, Satoru\|Takagi, Yoko\|Sugihara, Kenichi
PMID:	18607552

75.
Journal:	Cell Cycle. 2008 Aug;7(15):2427-33.
Title:	Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation.
Author:	Paris, Ramiro\|Henry, Ryan E\|Stephens, Sarah J\|McBryde, Meagan\|Espinosa, Joaquin M
PMID:	18677110

76.
Journal:	Oncogene. 2008 Nov 6;27(52):6657-66.
Title:	Full-length hdmX transcripts decrease following genotoxic stress.
Author:	Markey, M\|Berberich, S J
PMID:	18711402

77.
Journal:	Zhonghua Zhong Liu Za Zhi. 2008 May;30(5):335-8.
Title:	[Genetic polymorphism in MDM2 is associated with susceptibility to colorectal cancer in a Chinese population].
Author:	Liu, Jun-Niao\|Zhang, Xue-Mei\|Guo, Yong-Li\|Sun, Tong\|Lin, Dong-Xin\|Wen, Tan
PMID:	18953830

78.
Journal:	Br J Cancer. 2008 Dec 16;99(12):2001-5.
Title:	Statistical strategies to improve the efficiency of molecular studies of colorectal cancer prognosis.
Author:	Qu, P\|Chu, H\|Ibrahim, J G\|Peacock, J\|Shen, X J\|Tepper, J\|Sandler, R S\|Keku, T O
PMID:	19018265

79.
Journal:	Anal Bioanal Chem. 2009 Jul;394(5):1291-7.
Title:	Genotyping of single nucleotide polymorphism in MDM2 genes by universal fluorescence primer PCR and capillary electrophoresis.
Author:	Chen, Yen-Ling\|Chang, Ya-Sian\|Chang, Jan-Gowth\|Wu, Shou-Mei
PMID:	19015838

80.
Journal:	Int J Oncol. 2009 Jun;34(6):1637-43.
Title:	Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening.
Author:	Lee, Su-Jin\|Jung, Youn-Sang\|Lee, Sun-Hye\|Chung, Hye-Young\|Park, Bum-Joon
PMID:	19424582

81.
Journal:	Cancer Causes Control. 2009 Nov;20(9):1769-77.
Title:	Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome.
Author:	Chen, Jinyun\|Etzel, Carol J\|Amos, Christopher I\|Zhang, Qing\|Viscofsky, Nancy\|Lindor, Noralane M\|Lynch, Patrick M\|Frazier, Marsha L
PMID:	19690970

82.
Journal:	Anticancer Res. 2009 Oct;29(10):3733-40.
Title:	Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation.
Author:	Kim, Min Young\|Trudel, Laura J\|Wogan, Gerald N
PMID:	19846903

83.
Journal:	Cancer Lett. 2010 Jan 1;287(1):98-108.
Title:	Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author:	Hori, Takeshi\|Kondo, Takashi\|Kanamori, Masahiko\|Tabuchi, Yoshiaki\|Ogawa, Ryohei\|Zhao, Qing-Li\|Ahmed, Kanwal\|Yasuda, Taketoshi\|Seki, Shoji\|Suzuki, Kayo\|Kimura, Tomoatsu
PMID:	19577358

84.
Journal:	Biochem Pharmacol. 2010 Feb 15;79(4):565-74.
Title:	DNA damage response to the Mdm2 inhibitor nutlin-3.
Author:	Verma, Rajeev\|Rigatti, Marc J\|Belinsky, Glenn S\|Godman, Cassandra A\|Giardina, Charles
PMID:	19788889

85.
Journal:	Mol Cancer Ther. 2010 Feb;9(2):450-60.
Title:	A novel E1B-55kD-deleted oncolytic adenovirus carrying mutant KRAS-regulated hdm2 transgene exerts specific antitumor efficacy on colorectal cancer cells.
Author:	Liu, Chin-Cheng\|Liu, Jin-Hwang\|Wu, Suh-Chin\|Yen, Chueh-Chuan\|Chen, Wei-Shone\|Tsai, Ying-Chieh
PMID:	20124454

86.
Journal:	Recent Pat DNA Gene Seq. 2010 Jun;4(2):86-93.
Title:	Recent patents and advances in genomic biomarker discovery for colorectal cancers.
Author:	Quyun, Chen\|Ye, Zhiyun\|Lin, Sheng-Cai\|Lin, Biaoyang
PMID:	20426761

87.
Journal:	Genes Chromosomes Cancer. 2010 Jul;49(7):620-9.
Title:	MDM2 gene amplification in colorectal cancer is associated with disease progression at the primary site, but inversely correlated with distant metastasis.
Author:	Sugano, Nobuhiro\|Suda, Tetsuji\|Godai, Ten-I\|Tsuchida, Kazuhito\|Shiozawa, Manabu\|Sekiguchi, Hironobu\|Yoshihara, Mitsuyo\|Matsukuma, Shoichi\|Sakuma, Yuji\|Tsuchiya, Eiju\|Kameda, Yoichi\|Akaike, Makoto\|Miyagi, Yohei
PMID:	20461754

88.
Journal:	J Clin Invest. 2010 Dec;120(12):4493-506.
Title:	Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
Author:	Jung, Cho-Rok\|Lim, Jung Hwa\|Choi, Yoonjung\|Kim, Dae-Ghon\|Kang, Koo Jeong\|Noh, Seung-Moo\|Im, Dong-Soo
PMID:	21060154

89.
Journal:	Oncol Lett. 2010 Jan;1(1):23-29.
Title:	Molecular prognostic factors in rectal cancer treated by preoperative chemoradiotherapy.
Author:	Nam, Taek-Keun\|Lee, Ji-Shin\|Kim, Hyeong-Rok\|Ahn, Sung-Ja\|Song, Ju-Young\|Yoon, Mee Sun
PMID:	22966250

90.
Journal:	Med Oncol. 2011 Dec;28(4):981-5.
Title:	MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis.
Author:	Fang, Fang\|Yu, Xiao-Jia\|Yu, Lu\|Yao, Lei
PMID:	20503107

91.
Journal:	Apoptosis. 2011 Jan;16(1):35-44.
Title:	Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Author:	Ray, Ramesh M\|Bhattacharya, Sujoy\|Johnson, Leonard R
PMID:	20812030

92.
Journal:	Jpn J Clin Oncol. 2011 Feb;41(2):232-8.
Title:	TP53 R72P and MDM2 SNP309 polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study.
Author:	Joshi, Amit Man\|Budhathoki, Sanjeev\|Ohnaka, Keizo\|Mibu, Ryuichi\|Tanaka, Masao\|Kakeji, Yoshihiro\|Maehara, Yoshihiko\|Okamura, Takeshi\|Ikejiri, Koji\|Futami, Kitaroh\|Maekawa, Takafumi\|Yasunami, Yohichi
PMID:	21051533

93.
Journal:	Virchows Arch. 2011 Feb;458(2):197-203.
Title:	MDM2 gene amplification and protein expressions in colon carcinoma: is targeting MDM2 a new therapeutic option?
Author:	Hav, Monirath\|Libbrecht, Louis\|Ferdinande, Liesbeth\|Pattyn, Piet\|Laurent, Stephanie\|Peeters, Marc\|Praet, Marleen\|Pauwels, Patrick
PMID:	21113617

94.
Journal:	EMBO J. 2011 Mar 16;30(6):1040-53.
Title:	Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation.
Author:	Masuda, Kiyoshi\|Abdelmohsen, Kotb\|Kim, Mihee M\|Srikantan, Subramanya\|Lee, Eun Kyung\|Tominaga, Kumiko\|Selimyan, Roza\|Martindale, Jennifer L\|Yang, Xiaoling\|Lehrmann, Elin\|Zhang, Yongqing\|Becker, Kevin G\|Wang, Jian-Ying\|Kim, Hyeon Ho\|Gorospe, Myriam
PMID:	21317874

95.
Journal:	BMC Cancer. 2011 Feb 21;11:79.
Title:	A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation.
Author:	Valentine, Jane M\|Kumar, Sonia\|Moumen, Abdeladim
PMID:	21338495

96.
Journal:	Biochem Cell Biol. 2011 Jun;89(3):287-98.
Title:	LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Author:	Liu, Wei\|Dai, Qinsheng\|Lu, Na\|Wei, Libin\|Ha, Jun\|Rong, Jingjing\|Mu, Rong\|You, Qidong\|Li, Zhiyu\|Guo, Qinglong
PMID:	21491996

97.
Journal:	Oncol Rep. 2011 Jul;26(1):49-54.
Title:	Rare MDM4 gene amplification in colorectal cancer: The principle of a mutually exclusive relationship between MDM alteration and TP53 inactivation is not applicable.
Author:	Suda, Tetsuji\|Yoshihara, Mitsuyo\|Nakamura, Yoshiyasu\|Sekiguchi, Hironobu\|Godai, Ten-I\|Sugano, Nobuhiro\|Tsuchida, Kazuhito\|Shiozawa, Manabu\|Sakuma, Yuji\|Tsuchiya, Eiju\|Kameda, Yoichi\|Akaike, Makoto\|Matsukuma, Shoichi\|Miyagi, Yohei
PMID:	21503588

98.
Journal:	J Agric Food Chem. 2011 May 25;59(10):5357-63.
Title:	Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin.
Author:	Chang, Hsiang-Yu\|Kao, Ming-Ching\|Way, Tzong-Der\|Ho, Chi-Tang\|Fu, Earl
PMID:	21504235

99.
Journal:	J Drug Target. 2011 Dec;19(10):859-73.
Title:	Synchronized release of Doxil and Nutlin-3 by remote degradation of polysaccharide matrices and its possible use in the local treatment of colorectal cancer.
Author:	Nadler-Milbauer, Mirela\|Apter, Lior\|Haupt, Ygal\|Haupt, Sue\|Barenholz, Yechezkel\|Minko, Tamara\|Rubinstein, Abraham
PMID:	22082104

100.
Journal:	Nat Rev Gastroenterol Hepatol. 2011 Dec 13;9(1):4.
Title:	Cancer: Mdm2-regulated stabilization of HuR by neddylation in HCC and colon cancer--a possible target for therapy.
Author:	McLarnon, Andy
PMID:	22158377

101.
Journal:	Mol Cell. 2011 Dec 23;44(6):893-906.
Title:	Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
Author:	Matallanas, David\|Romano, David\|Al-Mulla, Fahd\|O'Neill, Eric\|Al-Ali, Waleed\|Crespo, Piero\|Doyle, Brendan\|Nixon, Colin\|Sansom, Owen\|Drosten, Matthias\|Barbacid, Mariano\|Kolch, Walter
PMID:	22195963

102.
Journal:	Mol Carcinog. 2012 May;51(5):363-78.
Title:	Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells.
Author:	Rigatti, Marc J\|Verma, Rajeev\|Belinsky, Glenn S\|Rosenberg, Daniel W\|Giardina, Charles
PMID:	21557332

103.
Journal:	Cancer. 2012 Feb 15;118(4):1110-8.
Title:	Identification of spliced variants of the proto-oncogene HDM2 in colorectal cancer.
Author:	Yu, Zhiwei\|Zhang, Bin\|Cui, Binbin\|Wang, Yihui\|Han, Peng\|Wang, Xishan
PMID:	21761395

104.
Journal:	DNA Cell Biol. 2012 Mar;31(3):355-9.
Title:	MDM2 SNP309 polymorphism and colorectal cancer risk: a meta-analysis.
Author:	Cao, Xiangming\|Zhang, Tingrong\|Zhao, Zhen\|Zhao, Tao
PMID:	21770737

105.
Journal:	DNA Cell Biol. 2012 Mar;31(3):270-1.
Title:	MDM2 SNP309 polymorphism and colorectal cancer risk: appraisal of a recent meta-analysis.
Author:	Tian, Jing\|Pan, Feng\|Pan, Yueyin\|Zhang, Ying
PMID:	22066579

106.
Journal:	Breast Cancer Res Treat. 2012 Jun;133(3):909-16.
Title:	Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.
Author:	Kim, Jin Cheon\|Yu, Jong Han\|Cho, Yoon Kyung\|Jung, Choon Sik\|Ahn, Sei Hyun\|Gong, Gyungyub\|Kim, Yong Sung\|Cho, Dong-Hyung
PMID:	22076481

107.
Journal:	J Biol Chem. 2012 Jan 2;287(1):641-9.
Title:	Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
Author:	Ding, Jie\|Polier, Gernot\|Kohler, Rebecca\|Giaisi, Marco\|Krammer, Peter H\|Li-Weber, Min
PMID:	22086925

108.
Journal:	Hepatology. 2012 Apr;55(4):1237-48.
Title:	Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.
Author:	Embade, Nieves\|Fernandez-Ramos, David\|Varela-Rey, Marta\|Beraza, Naiara\|Sini, Marcella\|Gutierrez de Juan, Virginia\|Woodhoo, Ashwin\|Martinez-Lopez, Nuria\|Rodriguez-Iruretagoyena, Begona\|Bustamante, Francisco Javier\|de la Hoz, Ana Belen\|Carracedo, Arkaitz\|Xi
PMID:	22095636

109.
Journal:	Exp Cell Res. 2012 Mar 10;318(5):539-49.
Title:	Abrogation of Gli3 expression suppresses the growth of colon cancer cells via activation of p53.
Author:	Kang, Han Na\|Oh, Sang Cheul\|Kim, Jun Suk\|Yoo, Young A
PMID:	22227409

110.
Journal:	PLoS One. 2012;7(1):e29750.
Title:	MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5.
Author:	Cai, Chunxiao\|Ashktorab, Hassan\|Pang, Xiaowu\|Zhao, Yuan\|Sha, Wei\|Liu, Yulan\|Gu, Xinbin
PMID:	22235338

111.
Journal:	Eur J Gastroenterol Hepatol. 2012 Mar;24(3):320-7.
Title:	Impact of MDM2 polymorphism: increased risk of developing colorectal cancer and a poor prognosis in the Tunisian population.
Author:	Chaar, Ines\|Arfaoui, Toumi Amira\|El Amine, El Hadj Olfa\|Mahmoud, Lilia Ben\|Khiari, Mariem\|Sammoud, Soraya\|Lounis, Amine\|Amara, Semeh\|Gharbi, Lassad\|Hmida, Abdelmajid Ben\|Mzabi, Sabeh\|Bouraoui, Saadia
PMID:	22266832

112.
Journal:	Int J Colorectal Dis. 2012 Nov;27(11):1391-9.
Title:	Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.
Author:	Knosel, Thomas\|Chen, Yuan\|Hotovy, Stefanie\|Settmacher, Utz\|Altendorf-Hofmann, Annelore\|Petersen, Iver
PMID:	22438068

113.
Journal:	Clin Epigenetics. 2012 Jun 15;4(1):9.
Title:	Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1beta in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.
Author:	Nyiraneza, Christine\|Sempoux, Christine\|Detry, Roger\|Kartheuser, Alex\|Dahan, Karin
PMID:	22703554

114.
Journal:	PLoS One. 2012;7(6):e39789.
Title:	Cross-regulation of protein stability by p53 and nuclear receptor SHP.
Author:	Yang, Zhihong\|Zhang, Yuxia\|Kemper, Jongsook Kim\|Wang, Li
PMID:	22737255

115.
Journal:	Mol Biol Rep. 2012 Oct;39(10):9661-8.
Title:	Polymorphisms in TP53 and MDM2 contribute to higher risk of colorectal cancer in Chinese population: a hospital-based, case-control study.
Author:	Zhang, Yuxing\|Liu, Li\|Tang, Yingchun\|Chen, Chao\|Wang, Qian\|Xu, Jun\|Yang, Chao\|Miao, Xiaoping\|Wei, Sheng\|Chen, Jigui\|Nie, Shaofa
PMID:	22744426

116.
Journal:	Indian J Pathol Microbiol. 2012 Apr-Jun;55(2):192-5.
Title:	Study of the Murine Double Minute 2 status in patients with gastric and colorectal carcinomas and its correlation with prognostic factors.
Author:	Sepideh, Siadati\|Mohammadreza, Jalali Nadoushan\|Ali, Davati\|Gholamreza, Torabi Parizi\|Samira, Ghasemi
PMID:	22771642

117.
Journal:	PLoS One. 2012;7(8):e42034.
Title:	MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame.
Author:	Mandke, Pooja\|Wyatt, Nicholas\|Fraser, Jillian\|Bates, Benjamin\|Berberich, Steven J\|Markey, Michael P
PMID:	22870278

118.
Journal:	Oncol Rep. 2012 Nov;28(5):1551-8.
Title:	Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines.
Author:	Chiba, Mitsuru\|Kimura, Misako\|Asari, Saya
PMID:	22895844

119.
Journal:	World J Gastroenterol. 2012 Aug 14;18(30):4051-8.
Title:	Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer.
Author:	Chen, Tan-Hsia\|Huang, Chi-Chou\|Yeh, Kun-Tu\|Chang, Shu-Hau\|Chang, Shih-Wen\|Sung, Wen-Wei\|Cheng, Ya-Wen\|Lee, Huei
PMID:	22912557

120.
Journal:	J Biol Chem. 2012 Oct 19;287(43):36443-54.
Title:	Identification of HEXIM1 as a positive regulator of p53.
Author:	Lew, Qiao Jing\|Chia, Yi Ling\|Chu, Kai Ling\|Lam, Yuen Ting\|Gurumurthy, Meera\|Xu, Shengli\|Lam, Kong Peng\|Cheong, Nge\|Chao, Sheng-Hao
PMID:	22948151

121.
Journal:	Anticancer Agents Med Chem. 2013 May;13(4):532-45.
Title:	A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
Author:	Golubovskaya, Vita M\|Palma, Nadia L\|Zheng, Min\|Ho, Baotran\|Magis, Andrew\|Ostrov, David\|Cance, William G
PMID:	22292771

122.
Journal:	Appl Immunohistochem Mol Morphol. 2013 May;21(3):228-36.
Title:	Relationship between MDM2 and p53 alterations in colorectal cancer and their involvement and prognostic value in the Tunisian population.
Author:	Chaar, Ines\|Amara, Sameh\|Khiari, Mariem\|Ounissi, Donia\|Dhraif, Monia\|Ben Hamida, Abd E M\|Gharbi, Lassad\|Mzabi, Sabeh\|Bouraoui, Saadia
PMID:	22914606

123.
Journal:	Int J Biochem Cell Biol. 2013 Mar;45(3):684-91.
Title:	Knockdown of FAM3B triggers cell apoptosis through p53-dependent pathway.
Author:	Mou, Haiwei\|Li, Zongmeng\|Yao, Pengle\|Zhuo, Shu\|Luan, Wei\|Deng, Bo\|Qian, Lihua\|Yang, Mengmei\|Mei, Hong\|Le, Yingying
PMID:	23246487

124.
Journal:	Bioorg Med Chem. 2013 Apr 15;21(8):2418-25.
Title:	Synthesis and evaluation of an imidazole derivative-fluorescein conjugate.
Author:	Ghosh, Pradip\|Zhang, Jiawei\|Shi, Zheng-Zheng\|Li, King
PMID:	23477941

125.
Journal:	DNA Cell Biol. 2013 Jul;32(7):400-8.
Title:	Do CDKN2 p16 540 C>G, CDKN2 p16 580 C>T, and MDM2 SNP309 T>G gene variants act on colorectal cancer development or progression?
Author:	Tuna, Gulay\|Kucukhuseyin, Ozlem\|Arikan, Soykan\|Kaytan Saglam, Esra\|Guler, Erkan\|Cacina, Canan\|Oztop, Ozge\|Turan, Saime\|Korkmaz, Gurbet\|Yaylim, Ilhan
PMID:	23777425

126.
Journal:	J Biol Chem. 2013 Aug 30;288(35):25244-53.
Title:	Regulation of hypoxia-inducible factor 1alpha (HIF-1alpha) by lysophosphatidic acid is dependent on interplay between p53 and Kruppel-like factor 5.
Author:	Lee, Sei-Jung\|No, Yi Ran\|Dang, Duyen T\|Dang, Long H\|Yang, Vincent W\|Shim, Hyunsuk\|Yun, C Chris
PMID:	23880760

127.
Journal:	Tumour Biol. 2013 Dec;34(6):3721-9.
Title:	Current evidence on the relationship between SNP309 polymorphism in the MDM2 gene and colorectal cancer risk.
Author:	Fu, Qiang\|Zhang, Guoqiang\|Chen, Hongwei\|Zheng, Youwei\|Cheng, Jing
PMID:	23912932

128.
Journal:	PLoS One. 2013 Sep 30;8(9):e76031.
Title:	An updated meta-analysis on the association of MDM2 SNP309 polymorphism with colorectal cancer risk.
Author:	Qin, Xue\|Peng, Qiliu\|Tang, Weizhong\|Lao, Xianjun\|Chen, Zhiping\|Lai, Hao\|Deng, Yan\|Mo, Cuiju\|Sui, Jingzhe\|Wu, Junrong\|Zhai, Limin\|Yang, Shi\|Li, Shan\|Zhao, Jinmin
PMID:	24098760

129.
Journal:	Sci Rep. 2013 Nov 14;3:3219.
Title:	Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress.
Author:	Yang, Pei-Ming\|Lin, Yi-Ting\|Shun, Chia-Tung\|Lin, Shan-Hu\|Wei, Tzu-Tang\|Chuang, Shu-Hui\|Wu, Ming-Shiang\|Chen, Ching-Chow
PMID:	24225777

130.
Journal:	Cell Death Dis. 2013 Dec 12;4:e963.
Title:	PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.
Author:	Valentino, T\|Palmieri, D\|Vitiello, M\|Pierantoni, G M\|Fusco, A\|Fedele, M
PMID:	24336083

131.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2013 Dec;33(12):1787-91.
Title:	[Application of genome-wide genechip for screening and identifying genes related to CD133(+)CD200(+) colorectal cancer stem cells].
Author:	Zhang, Shanshan\|Li, Lixuan\|Huang, Zaiwei\|Xin, Xiaomin\|Xiao, Bing
PMID:	24369246

132.
Journal:	Tumour Biol. 2014 Feb;35(2):1439-49.
Title:	Biological significance of promoter hypermethylation of p14/ARF gene: relationships to p53 mutational status in Tunisian population with colorectal carcinoma.
Author:	Chaar, Ines\|Amara, Sameh\|Elamine, Olfa Elhadj\|Khiari, Mariem\|Ounissi, Donia\|Khalfallah, Taher\|Ben Hmida, Abdelmajid\|Mzabi, Sabeh\|Bouraoui, Saadia
PMID:	24065196

133.
Journal:	Br J Cancer. 2014 Feb 4;110(3):656-67.
Title:	p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors.
Author:	Sonnemann, J\|Marx, C\|Becker, S\|Wittig, S\|Palani, C D\|Kramer, O H\|Beck, J F
PMID:	24281001

134.
Journal:	Int J Oncol. 2014 Apr;44(4):1309-15.
Title:	Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
Author:	Park, Ki-Woong\|Kundu, Juthika\|Chae, In-Gyeong\|Kim, Do-Hee\|Yu, Mi-Hee\|Kundu, Joydeb Kumar\|Chun, Kyung-Soo
PMID:	24481553

135.
Journal:	J Comput Aided Mol Des. 2014 Feb;28(2):89-97.
Title:	Prospective virtual screening for novel p53-MDM2 inhibitors using ultrafast shape recognition.
Author:	Patil, Sachin P\|Ballester, Pedro J\|Kerezsi, Cassidy R
PMID:	24554192

136.
Journal:	J Ethnopharmacol. 2014 Apr 28;153(2):375-85.
Title:	Swietenia macrophylla King induces mitochondrial-mediated apoptosis through p53 upregulation in HCT116 colorectal carcinoma cells.
Author:	Goh, Bey Hing\|Chan, Chim Kei\|Kamarudin, Muhamad Noor Alfarizal\|Abdul Kadir, Habsah
PMID:	24613274

137.
Journal:	BMC Genomics. 2014 Mar 13;15:190.
Title:	Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author:	Castle, John C\|Loewer, Martin\|Boegel, Sebastian\|de Graaf, Jos\|Bender, Christian\|Tadmor, Arbel D\|Boisguerin, Valesca\|Bukur, Thomas\|Sorn, Patrick\|Paret, Claudia\|Diken, Mustafa\|Kreiter, Sebastian\|Tureci, Ozlem\|Sahin, Ugur
PMID:	24621249

138.
Journal:	Int J Biol Sci. 2014 Feb 21;10(3):285-95.
Title:	Capsaicin mediates cell cycle arrest and apoptosis in human colon cancer cells via stabilizing and activating p53.
Author:	Jin, Junzhe\|Lin, Guofu\|Huang, Hong\|Xu, Dong\|Yu, Hao\|Ma, Xu\|Zhu, Lisi\|Ma, Dongyan\|Jiang, Honglei
PMID:	24643130

139.
Journal:	Sci Rep. 2014 May 6;4:4851.
Title:	MDM2 SNP309 polymorphism is associated with colorectal cancer risk.
Author:	Wang, Weizhi\|Du, Mulong\|Gu, Dongying\|Zhu, Lingjun\|Chu, Haiyan\|Tong, Na\|Zhang, Zhengdong\|Xu, Zekuan\|Wang, Meilin
PMID:	24797837

140.
Journal:	Biochem Biophys Res Commun. 2014 Jul 4;449(3):319-26.
Title:	Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity.
Author:	Kasim, Vivi\|Huang, Can\|Zhang, Jing\|Jia, Huizhen\|Wang, Yunxia\|Yang, Li\|Miyagishi, Makoto\|Wu, Shourong
PMID:	24845566

141.
Journal:	Eur J Med Chem. 2014 Jun 23;81:277-88.
Title:	Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction.
Author:	Zheng, Guang-hui\|Shen, Jia-jia\|Zhan, Yue-chen\|Yi, Hong\|Xue, Si-tu\|Wang, Zhen\|Ji, Xing-yue\|Li, Zhuo-rong
PMID:	24852275

142.
Journal:	Cancer Res. 2014 Oct 15;74(20):5855-65.
Title:	SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
Author:	Wang, Shaomeng\|Sun, Wei\|Zhao, Yujun\|McEachern, Donna\|Meaux, Isabelle\|Barriere, Cedric\|Stuckey, Jeanne A\|Meagher, Jennifer L\|Bai, Longchuan\|Liu, Liu\|Hoffman-Luca, Cassandra Gianna\|Lu, Jianfeng\|Shangary, Sanjeev\|Yu, Shanghai\|Bernard, Denzil\|Aguilar, Angelo\|
PMID:	25145672

143.
Journal:	Oncotarget. 2014 Oct 15;5(19):9106-17.
Title:	MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling.
Author:	Zhang, Cen\|Liu, Juan\|Wang, Xiaolong\|Wu, Rui\|Lin, Meihua\|Laddha, Saurabh V\|Yang, Qifeng\|Chan, Chang S\|Feng, Zhaohui
PMID:	25193859

144.
Journal:	Nat Commun. 2014 Oct 17;5:5218.
Title:	LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.
Author:	Yu, Haiyang\|Yue, Xuetian\|Zhao, Yuhan\|Li, Xiaoyan\|Wu, Lihua\|Zhang, Cen\|Liu, Zhen\|Lin, Kevin\|Xu-Monette, Zijun Y\|Young, Ken H\|Liu, Juan\|Shen, Zhiyuan\|Feng, Zhaohui\|Hu, Wenwei
PMID:	25323535

145.
Journal:	World J Gastroenterol. 2014 Oct 21;20(39):14463-71.
Title:	Gene expression profile of peripheral blood in colorectal cancer.
Author:	Chang, Yu-Tien\|Huang, Chi-Shuan\|Yao, Chung-Tay\|Su, Sui-Lung\|Terng, Harn-Jing\|Chou, Hsiu-Ling\|Chou, Yu-Ching\|Chen, Kang-Hua\|Shih, Yun-Wen\|Lu, Chian-Yu\|Lai, Ching-Huang\|Jian, Chen-En\|Lin, Chiao-Huang\|Chen, Chien-Ting\|Wu, Yi-Syuan\|Lin, Ke-Shin\|Wetter, Thomas
PMID:	25339833

146.
Journal:	Med Oncol. 2014 Dec;31(12):288.
Title:	Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF-MDM2-p53 pathway.
Author:	Zhao, Yi\|Yao, Yun-hong\|Li, Li\|An, Wei-fang\|Chen, Hong-zen\|Sun, Li-ping\|Kang, Hai-xian\|Wang, Sen\|Hu, Xin-rong
PMID:	25367850

147.
Journal:	PLoS One. 2014 Nov 7;9(11):e110844.
Title:	Novel roles for p53 in the genesis and targeting of tetraploid cancer cells.
Author:	Davaadelger, Batzaya\|Shen, Hong\|Maki, Carl G
PMID:	25380055

148.
Journal:	J Med Chem. 2014 Dec 26;57(24):10499-511.
Title:	Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction.
Author:	Rew, Yosup\|Sun, Daqing\|Yan, Xuelei\|Beck, Hilary P\|Canon, Jude\|Chen, Ada\|Duquette, Jason\|Eksterowicz, John\|Fox, Brian M\|Fu, Jiasheng\|Gonzalez, Ana Z\|Houze, Jonathan\|Huang, Xin\|Jiang, Min\|Jin, Lixia\|Li, Yihong\|Li, Zhihong\|Ling, Yun\|Lo, Mei-Chu\|Long, Alexand
PMID:	25384157

149.
Journal:	Cancer Res. 2014 Dec 15;74(24):7487-97.
Title:	FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX.
Author:	Ling, Xiang\|Xu, Chao\|Fan, Chuandong\|Zhong, Kai\|Li, Fengzhi\|Wang, Xinjiang
PMID:	25512388

150.
Journal:	Cell Death Differ. 2015 Jan;22(1):118-30.
Title:	L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells.
Author:	Ayroldi, E\|Petrillo, M G\|Bastianelli, A\|Marchetti, M C\|Ronchetti, S\|Nocentini, G\|Ricciotti, L\|Cannarile, L\|Riccardi, C
PMID:	25168242

151.
Journal:	Int J Oncol. 2015 Jan;46(1):342-50.
Title:	A novel pyrido-thieno-pyrimidine derivative activates p53 through induction of phosphorylation and acetylation in colorectal cancer cells.
Author:	Kang, Mi Ae\|Kim, Mi-Sook\|Kim, Ji Young\|Shin, Young-Joo\|Song, Jie-Young\|Jeong, Jae-Hoon
PMID:	25338966

152.
Journal:	J Comput Aided Mol Des. 2015 Feb;29(2):155-63.
Title:	Identification of antipsychotic drug fluspirilene as a potential p53-MDM2 inhibitor: a combined computational and experimental study.
Author:	Patil, Sachin P\|Pacitti, Michael F\|Gilroy, Kevin S\|Ruggiero, John C\|Griffin, Jonathan D\|Butera, Joseph J\|Notarfrancesco, Joseph M\|Tran, Shawn\|Stoddart, John W
PMID:	25377899

153.
Journal:	J Pathol. 2015 Mar;235(4):656-67.
Title:	UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
Author:	Zhang, Xiao-Wei\|Wang, Xiao-Feng\|Ni, Su-Jie\|Qin, Wei\|Zhao, Li-Qin\|Hua, Rui-Xi\|Lu, You-Wei\|Li, Jin\|Dimri, Goberdhan P\|Guo, Wei-Jian
PMID:	25382750

154.
Journal:	Oncogene. 2015 Aug 13;34(33):4412-20.
Title:	Impact of the Mdm2(SNP309-G) allele on a murine model of colorectal cancer.
Author:	Zhang, X\|Pageon, L\|Post, S M
PMID:	25435368

155.
Journal:	Pathol Oncol Res. 2015 Jul;21(3):629-35.
Title:	TP53 Arg 72Pro and MDM2 SNP309 polymorphisms and colorectal cancer risk: a west Algerian population study.
Author:	Abderrahmane, Rym\|Louhibi, Lotfi\|Moghtit, Fatima Zohra\|Boubekeur, Amina\|Benseddik, Khedidja\|Boudjema, Abdellah\|Benrrahal, Fouzia\|Aberkane, Meriem\|Fodil, Mostefa\|Saidi-Mehtar, Nadhira
PMID:	25537146

156.
Journal:	Cell Cycle. 2015;14(7):1046-58.
Title:	MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway.
Author:	Wang, Bo\|Shen, Zhan-long\|Gao, Zhi-dong\|Zhao, Gang\|Wang, Chun-you\|Yang, Yang\|Zhang, Ji-zhun\|Yan, Yi-chao\|Shen, Chao\|Jiang, Ke-wei\|Ye, Ying-jiang\|Wang, Shan
PMID:	25602366

157.
Journal:	PLoS One. 2015 Jan 28;10(1):e0116984.
Title:	Modulation of intracellular calcium levels by calcium lactate affects colon cancer cell motility through calcium-dependent calpain.
Author:	Sundaramoorthy, Pasupathi\|Sim, Jae Jun\|Jang, Yeong-Su\|Mishra, Siddhartha Kumar\|Jeong, Keun-Yeong\|Mander, Poonam\|Chul, Oh Byung\|Shim, Won-Sik\|Oh, Seung Hyun\|Nam, Ky-Youb\|Kim, Hwan Mook
PMID:	25629974

158.
Journal:	Oncotarget. 2015 Feb 28;6(6):4202-13.
Title:	RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.
Author:	Guo, Jing\|Yang, Yage\|Yang, Yunsheng\|Linghu, Enqiang\|Zhan, Qimin\|Brock, Malcolm V\|Herman, James G\|Zhang, Bingyong\|Guo, Mingzhou
PMID:	25638156

159.
Journal:	Tumour Biol. 2015 Mar;36(3):1437-44.
Title:	CP-31398 prevents the growth of p53-mutated colorectal cancer cells in vitro and in vivo.
Author:	He, Xingxing\|Kong, Xinjuan\|Yan, Junwei\|Yan, Jingjun\|Zhang, Yunan\|Wu, Qian\|Chang, Ying\|Shang, Haitao\|Dou, Qian\|Song, Yuhu\|Liu, Fang
PMID:	25663456

160.
Journal:	Br J Cancer. 2015 Mar 17;112(6):1114-20.
Title:	Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
Author:	Zajkowicz, A\|Butkiewicz, D\|Drosik, A\|Giglok, M\|Suwinski, R\|Rusin, M
PMID:	25742468

161.
Journal:	Cell Physiol Biochem. 2015;35(5):2006-18.
Title:	SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.
Author:	D'Antona, Lucia\|Amato, Rosario\|Talarico, Cristina\|Ortuso, Francesco\|Menniti, Miranda\|Dattilo, Vincenzo\|Iuliano, Rodolfo\|Gigliotti, Francesco\|Artese, Anna\|Costa, Giosue\|Schenone, Silvia\|Musumeci, Francesca\|Abbruzzese, Claudia\|Botta, Lorenzo\|Trapasso, Franc
PMID:	25871776

162.
Journal:	Int J Mol Sci. 2015 May 6;16(5):10242-66.
Title:	The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning.
Author:	Hull, Rodney\|Oosthuysen, Brent\|Cajee, Umar-Faruq\|Mokgohloa, Lehlogonolo\|Nweke, Ekene\|Antunes, Ricardo Jorge\|Coetzer, Theresa H T\|Ntwasa, Monde
PMID:	25955646

163.
Journal:	Oncol Rep. 2015 Aug;34(2):763-70.
Title:	Growth inhibitory effect of adenovirus-mediated tissue-targeted expression of ribosomal protein L23 on human colorectal carcinoma cells.
Author:	Fang, Henghu\|Kang, Jingbo\|Du, Rui\|Zhao, Xiangfei\|Zhang, Xinhong\|Ren, Dongqing\|Zhang, Yafei\|Lu, Zejun\|Wu, Shanshan\|Zheng, Wei\|Wen, Juyi
PMID:	26044651

164.
Journal:	Inflamm Bowel Dis. 2015 Sep;21(9):2039-51.
Title:	miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis.
Author:	Benderska, Natalya\|Dittrich, Anna-Lena\|Knaup, Sabine\|Rau, Tilman T\|Neufert, Clemens\|Wach, Sven\|Fahlbusch, Fabian B\|Rauh, Manfred\|Wirtz, Ralph M\|Agaimy, Abbas\|Srinivasan, Swetha\|Mahadevan, Vijayalakshmi\|Rummele, Petra\|Rapti, Emmanouela\|Gazouli, Maria\|Hartm
PMID:	26083618

165.
Journal:	J Nat Sci. 2015;1(7):e131.
Title:	LIF is a new p53 negative regulator.
Author:	Liu, Juan\|Yu, Haiyang\|Hu, Wenwei
PMID:	26161442

166.
Journal:	Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10931-4.
Title:	A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization.
Author:	Wang, Yuanxiang\|Chou, Danny Hung-Chieh
PMID:	26189498

167.
Journal:	Cancer Res. 2015 Sep 15;75(18):3842-52.
Title:	Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.
Author:	Zhang, Shengliang\|Zhou, Lanlan\|Hong, Bo\|van den Heuvel, A Pieter J\|Prabhu, Varun V\|Warfel, Noel A\|Kline, Christina Leah B\|Dicker, David T\|Kopelovich, Levy\|El-Deiry, Wafik S
PMID:	26294215

168.
Journal:	Sci Rep. 2015 Oct 8;5:14739.
Title:	Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.
Author:	Lu, Junyan\|Zeng, Hanlin\|Liang, Zhongjie\|Chen, Limin\|Zhang, Liyi\|Zhang, Hao\|Liu, Hong\|Jiang, Hualiang\|Shen, Bairong\|Huang, Ming\|Geng, Meiyu\|Spiegel, Sarah\|Luo, Cheng
PMID:	26446703

169.
Journal:	Oncotarget. 2015 Nov 10;6(35):37511-25.
Title:	Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
Author:	Talarico, Cristina\|D'Antona, Lucia\|Scumaci, Domenica\|Barone, Agnese\|Gigliotti, Francesco\|Fiumara, Claudia Vincenza\|Dattilo, Vincenzo\|Gallo, Enzo\|Visca, Paolo\|Ortuso, Francesco\|Abbruzzese, Claudia\|Botta, Lorenzo\|Schenone, Silvia\|Cuda, Giovanni\|Alcaro, Stef
PMID:	26462020

170.
Journal:	Cell Death Discov. 2015;1.
Title:	p53 Configures the G2/M Arrest Response of Nucleostemin-Deficient Cells.
Author:	Huang, Guanqun\|Meng, Lingjun\|Tsai, Robert Y L
PMID:	26835157

171.
Journal:	Mol Carcinog. 2016 Jan;55(1):15-26.
Title:	The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.
Author:	Read, Martin L\|Seed, Robert I\|Modasia, Bhavika\|Kwan, Perkin P K\|Sharma, Neil\|Smith, Vicki E\|Watkins, Rachel J\|Bansal, Sukhchain\|Gagliano, Teresa\|Stratford, Anna L\|Ismail, Tariq\|Wakelam, Michael J O\|Kim, Dae S\|Ward, Stephen T\|Boelaert, Kristien\|Franklyn, J
PMID:	25408419

172.
Journal:	Mol Carcinog. 2016 Jun;55(6):1096-110.
Title:	Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells.
Author:	Kim, Do-Hee\|Park, Ki-Woong\|Chae, In Gyeong\|Kundu, Juthika\|Kim, Eun-Hee\|Kundu, Joydeb Kumar\|Chun, Kyung-Soo
PMID:	26152521

173.
Journal:	Nat Chem Biol. 2016 Jan;12(1):22-8.
Title:	CRISPR-Cas9-based target validation for p53-reactivating model compounds.
Author:	Wanzel, Michael\|Vischedyk, Jonas B\|Gittler, Miriam P\|Gremke, Niklas\|Seiz, Julia R\|Hefter, Mirjam\|Noack, Magdalena\|Savai, Rajkumar\|Mernberger, Marco\|Charles, Joel P\|Schneikert, Jean\|Bretz, Anne Catherine\|Nist, Andrea\|Stiewe, Thorsten
PMID:	26595461

174.
Journal:	Cell Cycle. 2016;15(1):41-51.
Title:	Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53.
Author:	Russo, Annapina\|Pagliara, Valentina\|Albano, Francesco\|Esposito, Davide\|Sagar, Vinay\|Loreni, Fabrizio\|Irace, Carlo\|Santamaria, Rita\|Russo, Giulia
PMID:	26636733

175.
Journal:	Chem Pharm Bull (Tokyo). 2016;64(1):34-41.
Title:	Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex.
Author:	Rezk, Mohamed Salah\|Abdel-Halim, Mohammad\|Keeton, Adam\|Franklin, Derek\|Bauer, Matthias\|Boeckler, Frank Michael\|Engel, Matthias\|Hartmann, Rolf Wolfgang\|Zhang, Yanping\|Piazza, Gary Anthony\|Abadi, Ashraf Hassan
PMID:	26726742

176.
Journal:	Sci Rep. 2016 Jan 22;6:19793.
Title:	Study of Arsenic Sulfide in Solid Tumor Cells Reveals Regulation of Nuclear Factors of Activated T-cells by PML and p53.
Author:	Ding, Wenping\|Tong, Yingying\|Zhang, Xiuli\|Pan, Minggui\|Chen, Siyu
PMID:	26795951

177.
Journal:	Oncotarget. 2016 Feb 23;7(8):8783-96.
Title:	microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
Author:	Zhang, Cen\|Liu, Juan\|Tan, Chunwen\|Yue, Xuetian\|Zhao, Yuhan\|Peng, Jiaping\|Wang, Xiaolong\|Laddha, Saurabh V\|Chan, Chang S\|Zheng, Shu\|Hu, Wenwei\|Feng, Zhaohui
PMID:	26840028

178.
Journal:	Int J Oncol. 2016 Apr;48(4):1426-36.
Title:	Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor.
Author:	Basak, Debasish\|Punganuru, Surendra R\|Srivenugopal, Kalkunte S
PMID:	26848023

179.
Journal:	BMC Syst Biol. 2016 Feb 11;10:16.
Title:	Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.
Author:	Pavel, Ana B\|Sonkin, Dmitriy\|Reddy, Anupama
PMID:	26864072

180.
Journal:	Oncotarget. 2016 Mar 29;7(13):16420-32.
Title:	Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting.
Author:	Chen, Hongda\|Werner, Simone\|Butt, Julia\|Zornig, Inka\|Knebel, Phillip\|Michel, Angelika\|Eichmuller, Stefan B\|Jager, Dirk\|Waterboer, Tim\|Pawlita, Michael\|Brenner, Hermann
PMID:	26909861

181.
Journal:	Int J Pept Res Ther. 2016 Mar 1;22(1):67-81.
Title:	Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-Alkylation.
Author:	Micewicz, Ewa D\|Sharma, Shantanu\|Waring, Alan J\|Luong, Hai T\|McBride, William H\|Ruchala, Piotr
PMID:	26957954

182.
Journal:	Eur J Med Chem. 2016 May 23;114:328-36.
Title:	Design, synthesis and biological evaluation of novel benzimidazole-2-substituted phenyl or pyridine propyl ketene derivatives as antitumour agents.
Author:	Wu, Lin-tao\|Jiang, Zhi\|Shen, Jia-jia\|Yi, Hong\|Zhan, Yue-chen\|Sha, Ming-quan\|Wang, Zhen\|Xue, Si-tu\|Li, Zhuo-rong
PMID:	27017265

183.
Journal:	J Biol Chem. 2016 May 6;291(19):10131-47.
Title:	Modeling the Etiology of p53-mutated Cancer Cells.
Author:	Perez, Ricardo E\|Shen, Hong\|Duan, Lei\|Kim, Reuben H\|Kim, Terresa\|Park, No-Hee\|Maki, Carl G
PMID:	27022024

184.
Journal:	Oncotarget. 2016 May 10;7(19):28637-46.
Title:	Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate.
Author:	Gansmo, Liv B\|Vatten, Lars\|Romundstad, Pal\|Hveem, Kristian\|Ryan, Brid M\|Harris, Curtis C\|Knappskog, Stian\|Lonning, Per E
PMID:	27081698

185.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

186.
Journal:	Sci Rep. 2016 Jul 15;6:29869.
Title:	Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.
Author:	Bi, Haoran\|Tian, Tian\|Zhu, Lin\|Zhou, Haibo\|Hu, Hanqing\|Liu, Yanhong\|Li, Xia\|Hu, Fulan\|Zhao, Yashuang\|Wang, Guiyu
PMID:	27417709

187.
Journal:	Oncol Rep. 2016 Sep;36(3):1457-66.
Title:	Crocodile blood extract induces the apoptosis of lung cancer cells through PTEN activity.
Author:	Ou, Yuqian\|Ho, Wing Shing
PMID:	27431918

188.
Journal:	Sci Rep. 2016 Sep 14;6:33153.
Title:	MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer.
Author:	Helwa, Reham\|Gansmo, Liv B\|Romundstad, Pal\|Hveem, Kristian\|Vatten, Lars\|Ryan, Brid M\|Harris, Curtis C\|Lonning, Per E\|Knappskog, Stian
PMID:	27624283

189.
Journal:	Oncotarget. 2016 Oct 25;7(43):69816-69828.
Title:	Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.
Author:	Koppens, Martijn A J\|Bounova, Gergana\|Cornelissen-Steijger, Paulien\|de Vries, Nienke\|Sansom, Owen J\|Wessels, Lodewyk F A\|van Lohuizen, Maarten
PMID:	27634879

190.
Journal:	Mol Med Rep. 2016 Nov;14(5):4559-4566.
Title:	Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.
Author:	Yang, Lin\|Liu, Yanqing\|Wang, Mei\|Qian, Yayun\|Dong, Xiaoyun\|Gu, Hao\|Wang, Haibo\|Guo, Shiyu\|Hisamitsu, Tadashi
PMID:	27748879

191.
Journal:	Nat Commun. 2016 Dec 23;7:13755.
Title:	Pleckstrin homology domain-containing protein PHLDB3 supports cancer growth via a negative feedback loop involving p53.
Author:	Chao, Tengfei\|Zhou, Xiang\|Cao, Bo\|Liao, Peng\|Liu, Hongbing\|Chen, Yun\|Park, Hee-Won\|Zeng, Shelya X\|Lu, Hua
PMID:	28008906

192.
Journal:	Oncogene. 2017 Mar;36(10):1374-1383.
Title:	Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.
Author:	Liu, S\|Tackmann, N R\|Yang, J\|Zhang, Y
PMID:	27617574

193.
Journal:	Genes Chromosomes Cancer. 2017 Mar;56(3):199-213.
Title:	Novel mouse model recapitulates genome and transcriptome alterations in human colorectal carcinomas.
Author:	McNeil, Nicole E\|Padilla-Nash, Hesed M\|Buishand, Floryne O\|Hue, Yue\|Ried, Thomas
PMID:	27750367

194.
Journal:	Gut. 2017 Apr;66(4):666-682.
Title:	ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.
Author:	de Barrios, Oriol\|Gyorffy, Balazs\|Fernandez-Acenero, Maria Jesus\|Sanchez-Tillo, Ester\|Sanchez-Moral, Lidia\|Siles, Laura\|Esteve-Arenys, Anna\|Roue, Gael\|Casal, Jose I\|Darling, Douglas S\|Castells, Antoni\|Postigo, Antonio
PMID:	27965283

195.
Journal:	Cancer Cell. 2017 Jan 9;31(1):79-93.
Title:	BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
Author:	Lopez-Garcia, Carlos\|Sansregret, Laurent\|Domingo, Enric\|McGranahan, Nicholas\|Hobor, Sebastijan\|Birkbak, Nicolai Juul\|Horswell, Stuart\|Gronroos, Eva\|Favero, Francesco\|Rowan, Andrew J\|Matthews, Nicholas\|Begum, Sharmin\|Phillimore, Benjamin\|Burrell, Rebecca\|O
PMID:	28073006

196.
Journal:	PLoS One. 2017 Jan 19;12(1):e0170233.
Title:	Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.
Author:	Malami, Ibrahim\|Abdul, Ahmad Bustamam\|Abdullah, Rasedee\|Kassim, Nur Kartinee Bt\|Rosli, Rozita\|Yeap, Swee Keong\|Waziri, Peter\|Etti, Imaobong Christopher\|Bello, Muhammad Bashir
PMID:	28103302

197.
Journal:	BMC Cancer. 2017 Feb 3;17(1):97.
Title:	MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk.
Author:	Gansmo, Liv B\|Bjornslett, Merete\|Halle, Mari Kylleso\|Salvesen, Helga B\|Romundstad, Pal\|Hveem, Kristian\|Vatten, Lars\|Dorum, Anne\|Lonning, Per E\|Knappskog, Stian
PMID:	28158999

198.
Journal:	Biochem Pharmacol. 2017 May 1;131:29-39.
Title:	USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth.
Author:	An, Tao\|Gong, Yaxiao\|Li, Xue\|Kong, Lingmei\|Ma, Pengcheng\|Gong, Liang\|Zhu, Huifang\|Yu, Chunlei\|Liu, Jianmei\|Zhou, Hongyu\|Mao, Bingyu\|Li, Yan
PMID:	28216017

199.
Journal:	Oncotarget. 2017 Jun 6;8(23):37377-37393.
Title:	NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway.
Author:	Jana, Arundhati\|Krett, Nancy L\|Guzman, Grace\|Khalid, Ahmer\|Ozden, Ozkan\|Staudacher, Jonas J\|Bauer, Jessica\|Baik, Seung Hyun\|Carroll, Timothy\|Yazici, Cemal\|Jung, Barbara
PMID:	28418896

200.
Journal:	BMC Complement Altern Med. 2017 Apr 28;17(1):236.
Title:	Apoptosis-induced effects of extract from Artemisia annua Linne by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
Author:	Kim, Eun Ji\|Kim, Guen Tae\|Kim, Bo Min\|Lim, Eun Gyeong\|Kim, Sang-Yong\|Kim, Young Min
PMID:	28454566

201.
Journal:	Cell Death Dis. 2017 May 25;8(5):e2820.
Title:	PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth.
Author:	Zhang, Xiumei\|Zhang, Xia\|Li, Yang\|Shao, Yangguang\|Xiao, Jianying\|Zhu, Ge\|Li, Feng
PMID:	28542136

202.
Journal:	Nanomedicine (Lond). 2017 Jun 1.
Title:	PNC27 anticancer peptide as targeting ligand significantly improved antitumor efficacy of Doxil in HDM2-expressing cells.
Author:	Darban, Shahrzad Amiri\|Badiee, Ali\|Jaafari, Mahmoud Reza
PMID:	28565974

203.
Journal:	J Mol Biol. 2017 Nov 10;429(22):3546-3560.
Title:	Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.
Author:	Zhang, Wei\|Sartori, Maria A\|Makhnevych, Taras\|Federowicz, Kelly E\|Dong, Xiaohui\|Liu, Li\|Nim, Satra\|Dong, Aiping\|Yang, Jingsong\|Li, Yanjun\|Haddad, Dania\|Ernst, Andreas\|Heerding, Dirk\|Tong, Yufeng\|Moffat, Jason\|Sidhu, Sachdev S
PMID:	28587923

204.
Journal:	Oncogene. 2017 Nov 2;36(44):6109-6118.
Title:	Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients.
Author:	Tsoi, H\|Lam, K C\|Dong, Y\|Zhang, X\|Lee, C K\|Zhang, J\|Ng, S C\|Ng, S S M\|Zheng, S\|Chen, Y\|Fang, J\|Yu, J
PMID:	28692053

205.
Journal:	Oncogene. 2017 Nov 23;36(47):6581-6591.
Title:	Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers.
Author:	Hata, A N\|Rowley, S\|Archibald, H L\|Gomez-Caraballo, M\|Siddiqui, F M\|Ji, F\|Jung, J\|Light, M\|Lee, J S\|Debussche, L\|Sidhu, S\|Sadreyev, R I\|Watters, J\|Engelman, J A
PMID:	28783173

206.
Journal:	Eur J Med Chem. 2017 Oct 20;139:168-179.
Title:	In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.
Author:	Nunes, Rute C\|Ribeiro, Carlos J A\|Monteiro, Angelo\|Rodrigues, Cecilia M P\|Amaral, Joana D\|Santos, Maria M M
PMID:	28800455

207.
Journal:	Surg Case Rep. 2017 Aug 30;3(1):96.
Title:	Primary colonic well-differentiated / dedifferentiated liposarcoma of the ascending colon: a case report.
Author:	Sawayama, Hiroshi\|Yoshida, Naoya\|Miyamoto, Yuji\|Uchihara, Tomoyuki\|Toihata, Tasuku\|Yagi, Taisuke\|Hiyoshi, Yukiharu\|Iwatsuki, Masaaki\|Baba, Yoshifumi\|Baba, Hideo
PMID:	28856628

208.
Journal:	Oncotarget. 2017 Jun 20;8(39):65407-65413.
Title:	Colorectal carcinoma with osseous metaplasia.
Author:	Liu, Xibo\|Xu, Jinghong\|Chen, Lirong
PMID:	29029440

209.
Journal:	Protein J. 2017 Dec;36(6):513-522.
Title:	A Proteomics Analysis Reveals 9 Up-Regulated Proteins Associated with Altered Cell Signaling in Colon Cancer Patients.
Author:	Kit, Oleg I\|Vodolazhsky, Dmitry I\|Kutilin, Denis S\|Enin, Yaroslav S\|Gevorkyan, Yury A\|Zolotukhin, Peter V\|Boumber, Yanis\|Kharin, Leonid V\|Panina, Svetlana B
PMID:	29128960

210.
Journal:	Oncotarget. 2017 Dec 4;8(67):111597-111607.
Title:	LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)-Mdm2-P53-dependent cellular senescence.
Author:	Wang, Haibin\|Xu, Guoxing\|Huang, Zhengjie\|Li, Weizheng\|Cai, Huali\|Zhang, Yunda\|Xiong, Disheng\|Liu, Gang\|Wang, Shengjie\|Xue, Zengfu\|Luo, Qi
PMID:	29340077

211.
Journal:	World J Gastroenterol. 2017 Dec 28;23(48):8533-8543.
Title:	Analysis of 12 variants in the development of gastric and colorectal cancers.
Author:	Cavalcante, Giovanna C\|Amador, Marcos At\|Ribeiro Dos Santos, Andre M\|Carvalho, Darlen C\|Andrade, Roberta B\|Pereira, Esdras Eb\|Fernandes, Marianne R\|Costa, Danielle F\|Santos, Ney Pc\|Assumpcao, Paulo P\|Ribeiro Dos Santos, Andrea\|Santos, Sidney
PMID:	29358861

212.
Journal:	J Biochem Mol Toxicol. 2018 Jan;32(1).
Title:	Triggering p53 activation is essential in ziyuglycoside I-induced human retinoblastoma WERI-Rb-1 cell apoptosis.
Author:	Zhu, Xue\|Wang, Ke\|Yao, Yong\|Zhang, Kai\|Zhou, Fanfan\|Zhu, Ling
PMID:	28960612

213.
Journal:	Int J Oncol. 2018 Jan;52(1):211-218.
Title:	Simvastatin enhances the radiosensitivity of p53deficient cells via inhibition of mouse double minute 2 homolog.
Author:	Lee, Ji Young\|Kim, Mi-Sook\|Ju, Jae Eun\|Lee, Mi So\|Chung, Namhyun\|Jeong, Youn Kyoung
PMID:	29115437

214.
Journal:	Cancer Biol Ther. 2018 Jun 3;19(6):465-474.
Title:	DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a.
Author:	Zhou, Yalu\|Perez, Ricardo E\|Duan, Lei\|Maki, Carl G
PMID:	29394130

215.
Journal:	J Transl Med. 2018 Apr 10;16(1):89.
Title:	Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment.
Author:	Fitzgerald, Sean\|Espina, Virginia\|Liotta, Lance\|Sheehan, Katherine M\|O'Grady, Anthony\|Cummins, Robert\|O'Kennedy, Richard\|Kay, Elaine W\|Kijanka, Gregor S
PMID:	29631612

216.
Journal:	Blood. 2018 Jun 21;131(25):2789-2802.
Title:	TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.
Author:	Jethwa, Alexander\|Slabicki, Mikolaj\|Hullein, Jennifer\|Jentzsch, Marius\|Dalal, Vineet\|Rabe, Sophie\|Wagner, Lena\|Walther, Tatjana\|Klapper, Wolfram\|Bohnenberger, Hanibal\|Rettel, Mandy\|Lu, Junyan\|Smits, Arne H\|Stein, Frank\|Savitski, Mikhail M\|Huber, Wolfgang\|
PMID:	29653964

217.
Journal:	J Pathol. 2018 Jun 6.
Title:	Cyclophilin B induces chemoresistance by degrading wild-type p53 via interaction with MDM2 in colorectal cancer.
Author:	Choi, Tae Gyu\|Nguyen, Minh Nam\|Kim, Jieun\|Jo, Yong Hwa\|Jang, Miran\|Nguyen, Ngoc Ngo Yen\|Yun, Hyeong Rok\|Choe, Wonchae\|Kang, Insug\|Ha, Joohun\|Tang, Dean G\|Kim, Sung Soo
PMID:	29876924

218.
Journal:	Oncogene. 2018 Jun 13. pii: 10.1038/s41388-018-0352-7.
Title:	LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Author:	Zeng, Kaixuan\|Chen, Xiaoxiang\|Hu, Xiuxiu\|Liu, Xiangxiang\|Xu, Tao\|Sun, Huiling\|Pan, Yuqin\|He, Bangshun\|Wang, Shukui
PMID:	29899406

219.
Journal:	Eur J Med Chem. 2018 Aug 5;156:711-721.
Title:	Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity.
Author:	Brandao, Pedro\|Loureiro, Joana B\|Carvalho, Sylvie\|Hamadou, Meriem Hadjer\|Cravo, Sara\|Moreira, Joana\|Pereira, Daniela\|Palmeira, Andreia\|Pinto, Madalena\|Saraiva, Lucilia\|Cidade, Honorina
PMID:	30041135

220.
Journal:	Cancer Sci. 2018 Aug 27.
Title:	Bevacizumab-enhanced antitumor effect of 5-fluorouracil via upregulation of thymidine phosphorylase through vascular endothelial growth factor A/vascular endothelial growth factor receptor 2-specificity protein 1 pathway.
Author:	Liu, Wenyue\|Zhang, Jingwei\|Yao, Xuequan\|Jiang, Chao\|Ni, Ping\|Cheng, Lingge\|Liu, Jiali\|Ni, Suiying\|Chen, Qianying\|Li, Qingran\|Zhou, Kai\|Wang, Guangji\|Zhou, Fang
PMID:	30151975

221.
Journal:	J Pathol. 2018 Sep 3.
Title:	HMGA2 promotes intestinal tumorigenesis by facilitating MDM2-mediated ubiquitination and degradation of p53.
Author:	Wang, Yuhong\|Hu, Lin\|Wang, Jian\|Li, Xiangwei\|Sahengbieke, Sana\|Wu, Jingjing\|Lai, Maode
PMID:	30175854

222.
Journal:	Cancer Genomics Proteomics. 2018 Sep-Oct;15(5):405-411.
Title:	Contribution of Murine Double Minute 2 Genotypes to Colorectal Cancer Risk in Taiwan.
Author:	Yueh, Te-Cheng\|Hung, Yi-Wen\|Shih, Tzu-Ching\|Wu, Cheng-Nan\|Wang, Shou-Cheng\|Lai, Yi-Liang\|Hsu, Shih-Wei\|Wu, Ming-Hsien\|Fu, Chun-Kai\|Wang, Yun-Chi\|Ke, Tao-Wei\|Chang, Wen-Shin\|Tsai, Chia-Wen\|Bau, DA-Tian
PMID:	30194081

223.
Journal:	Oncol Lett. 2018 Oct;16(4):4640-4648.
Title:	Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells.
Author:	Li, Ting\|Sun, Wan\|Dong, Xiaoqiao\|Yu, Wenhua\|Cai, Jianyong\|Yuan, Qiang\|Shan, Letian\|Efferth, Thomas
PMID:	30197678

224.
Journal:	J Gastroenterol Hepatol. 2018 Sep 18.
Title:	RASSF1A suppresses colorectal tumor cell growth through p53-dependent p21(WAF1) activation.
Author:	Oh, Shin Ju\|Lee, Min-Goo\|Moon, Jung Rock\|Lee, Chang Kyun\|Chi, Sung-Gil\|Kim, Hyo Jong
PMID:	30226276

225.
Journal:	Technol Cancer Res Treat. 2018 Jan 1;17:1533033818801550.
Title:	The Study of MDM2 rs937283 Variant and Cancer Susceptibility in a Central Chinese Population.
Author:	Chen, Bifeng\|Wang, Jingdong\|Wang, Jieling\|Zhang, Jingli\|Gu, Xiuli\|Feng, Xianhong
PMID:	30244662

226.
Journal:	Turk J Gastroenterol. 2018 Sep;29(5):555-560.
Title:	Role of screening colonoscopy for colorectal tumors in Helicobacter pylori-related chronic gastritis with MDM2 SNP309 G/G homozygous: A prospective cross-sectional study in Thailand.
Author:	Tongtawee, Taweesak\|Simawaranon, Theeraya\|Wattanawongdon, Wareporn
PMID:	30260777

227.
Journal:	J Diabetes Res. 2018 Sep 9;2018:3274084.
Title:	Advanced Glycation End Products Increase MDM2 Expression via Transcription Factor KLF5.
Author:	Wang, Pu\|Lu, Yu Cheng\|Li, Yuan Fei\|Wang, Lan\|Lee, Shao Chin
PMID:	30271790

228.
Journal:	J Biol Regul Homeost Agents. 2018 Sep-Oct;32(5):1185-1189.
Title:	PIG3 suppresses gastric cancer proliferation by regulating p53- mediated apoptosis.
Author:	Chu, Y\|Li, D\|Zhang, H\|Ding, J\|Xu, P\|Qiu, X\|Zhang, H
PMID:	30334411

229.
Journal:	J Agric Food Chem. 2018 Oct 31.
Title:	Induction of Apoptosis and Cell-Cycle Arrest in Human Colon-Cancer Cells by Whole-Grain Alkylresorcinols via Activation of the p53 Pathway.
Author:	Fu, Junsheng\|Soroka, Dominique N\|Zhu, Yingdong\|Sang, Shengmin
PMID:	30354111

230.
Journal:	Mol Med Rep. 2018 Oct 30.
Title:	UBA2 promotes proliferation of colorectal cancer.
Author:	He, Ping\|Sun, Xun\|Cheng, Hong-Jing\|Zou, Ya-Bin\|Wang, Quan\|Zhou, Chang-Li\|Liu, Wan-Qi\|Hao, Yue-Ming\|Meng, Xiang-Wei
PMID:	30387828