Primary Site >> Stomach Cancer

Gene >> MCL1

Journal: Am J Pathol. 1996 Nov;149(5):1449-57.
Title: Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach.
Author: Krajewska, M|Fenoglio-Preiser, C M|Krajewski, S|Song, K|Macdonald, J S|Stemmerman, G|Reed, J C
PMID: 8909234
Journal: Carcinogenesis. 2001 Dec;22(12):1947-53.
Title: IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1.
Author: Lin, M T|Juan, C Y|Chang, K J|Chen, W J|Kuo, M L
PMID: 11751424
Journal: Cancer Biol Ther. 2006 Oct;5(10):1348-54. Epub 2006 Oct 26.
Title: Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells.
Author: Wacheck, Volker|Cejka, Daniel|Sieghart, Wolfgang|Losert, Doris|Strommer, Sabine|Crevenna, Richard|Monia, Brett P|Selzer, Edgar
PMID: 16969094
Journal: Cancer Biol Ther. 2006 Oct;5(10):1355-6. Epub 2006 Oct 14.
Title: Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer.
Author: Zangemeister-Wittke, Uwe|Huwiler, Andrea
PMID: 17172809
Journal: Int J Cancer. 2008 Jan 15;122(2):433-43.
Title: Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death.
Author: Yu, Hong-Gang|Ai, Yao-Wei|Yu, Liang-Liang|Zhou, Xiao-Dong|Liu, Jin|Li, Jun-Hua|Xu, Xi-Ming|Liu, Song|Chen, Jing|Liu, Fen|Qi, Yuan-Ling|Deng, Quanjun|Cao, Jun|Liu, Shi-Quan|Luo, He-Sheng|Yu, Jie-Ping
PMID: 17935137
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G798-805.
Title: Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor.
Author: Pritchard, D M|Berry, D|Przemeck, S M C|Campbell, F|Edwards, S W|Varro, A
PMID: 18719002
Journal: Oncogene. 2009 Jul 30;28(30):2738-44.
Title: Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
Author: Saito, Y|Suzuki, H|Tsugawa, H|Nakagawa, I|Matsuzaki, J|Kanai, Y|Hibi, T
PMID: 19503096
Journal: Eur J Cancer. 2010 Aug;46(12):2295-303.
Title: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion.
Author: Wang, Hui-Ju|Ruan, Hong-Jun|He, Xu-Jun|Ma, Ying-Yu|Jiang, Xiao-Ting|Xia, Ying-Jie|Ye, Zai-Yuan|Tao, Hou-Quan
PMID: 20712078
Journal: J Cell Mol Med. 2011 Feb;15(2):316-26.
Title: Low-dose taxotere enhances the ability of sorafenib to induce apoptosis in gastric cancer models.
Author: Tesei, Anna|Leonetti, Carlo|Zupi, Gabriella|Scarsella, Marco|Brigliadori, Giovanni|Ulivi, Paola|Fabbri, Francesco|Arienti, Chiara|Amadori, Dino|Passardi, Alessandro|Silvestrini, Rosella|Zoli, Wainer
PMID: 20015197
Journal: Anticancer Res. 2011 Mar;31(3):797-805.
Title: Citrate induces apoptotic cell death: a promising way to treat gastric carcinoma?
Author: Lu, Yunfei|Zhang, Xiaodong|Zhang, Haitian|Lan, Jiao|Huang, Guangwu|Varin, Emilie|Lincet, Hubert|Poulain, Laurent|Icard, Philippe
PMID: 21498699
Journal: J Pathol. 2011 Nov;225(3):438-47.
Title: Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop.
Author: Wu, Yan|Zhao, Qiyi|Peng, Chen|Sun, Lin|Li, Xue-Feng|Kuang, Dong-Ming
PMID: 21826665
Journal: Cell Cycle. 2012 Apr 15;11(8):1593-602.
Title: MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors.
Author: Labisso, Wajana L|Wirth, Matthias|Stojanovic, Natasa|Stauber, Roland H|Schnieke, Angelika|Schmid, Roland M|Kramer, Oliver H|Saur, Dieter|Schneider, Gunter
PMID: 22456335
Journal: Cancers (Basel). 2012 Dec 4;4(4):1318-32.
Title: Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells.
Author: Zhou, Xuezhang|Zhang, Yuyan|Li, Yong|Hao, Xiujing|Liu, Xiaoming|Wang, Yujiong
PMID: 24213508
Journal: Br J Cancer. 2012 Feb 14;106(4):685-92.
Title: The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis.
Author: Follet, J|Corcos, L|Baffet, G|Ezan, F|Morel, F|Simon, B|Le Jossic-Corcos, C
PMID: 22294184
Journal: Autophagy. 2012 Jan;8(1):109-21.
Title: Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1.
Author: Zhan, ZhenZhen|Li, Qun|Wu, Ping|Ye, Yan|Tseng, Hsin-Yi|Zhang, Linjie|Zhang, Xu Dong
PMID: 22108005
Journal: Int J Cancer. 2013 Apr 15;132(8):1751-60.
Title: The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.
Author: Saito, Yoshimasa|Suzuki, Hidekazu|Imaeda, Hiroyuki|Matsuzaki, Juntaro|Hirata, Kenro|Tsugawa, Hitoshi|Hibino, Sana|Kanai, Yae|Saito, Hidetsugu|Hibi, Toshifumi
PMID: 23001726
Journal: Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(11):G786-96.
Title: Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1.
Author: Noto, Jennifer M|Piazuelo, M Blanca|Chaturvedi, Rupesh|Bartel, Courtney A|Thatcher, Elizabeth J|Delgado, Alberto|Romero-Gallo, Judith|Wilson, Keith T|Correa, Pelayo|Patton, James G|Peek, Richard M Jr
PMID: 24136787
Journal: Neoplasma. 2014;61(2):136-43.
Title: Inhibition of MEK sensitizes gastric cancer cells to TRAIL-induced apoptosis.
Author: Wu, P|Cheng, Y W|Wang, J Y|Zhang, X D|Zhang, L J
PMID: 24299309
Journal: Int J Cancer. 2014 Nov 1;135(9):2065-76.
Title: Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study.
Author: Espinosa-Parrilla, Yolanda|Munoz, Xavier|Bonet, Catalina|Garcia, Nadia|Vencesla, Adoracion|Yiannakouris, Nikos|Naccarati, Alessio|Sieri, Sabina|Panico, Salvatore|Huerta, Jose M|Barricarte, Aurelio|Menendez, Virginia|Sanchez-Cantalejo, Emilio|Dorronsoro, M
PMID: 24643999
Journal: Asian Pac J Cancer Prev. 2014;15(16):6791-8.
Title: Silibinin inhibits proliferation, induces apoptosis and causes cell cycle arrest in human gastric cancer MGC803 cells via STAT3 pathway inhibition.
Author: Wang, Yi-Xin|Cai, Hong|Jiang, Gang|Zhou, Tian-Bao|Wu, Hai
PMID: 25169527
Journal: Int J Mol Med. 2014 Dec;34(6):1661-8.
Title: Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl1 and BclxL and increasing Bax and CHOP protein expression.
Author: Su, Chin-Cheng
PMID: 25270224
Journal: Mar Drugs. 2014 Oct 23;12(10):5295-315.
Title: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.
Author: Su, Ching-Chyuan|Chen, Jeff Yi-Fu|Din, Zhong-Hao|Su, Jui-Hsin|Yang, Zih-Yan|Chen, Yi-Jen|Wang, Robert Y L|Wu, Yu-Jen
PMID: 25342459
Journal: Int J Oncol. 2015 May;46(5):2154-62.
Title: Myeloid cell leukemia-1 regulates the cell growth and predicts prognosis in gastric cancer.
Author: Lee, Wan-Sik|Park, Young-Lan|Kim, Nuri|Oh, Hyung-Hoon|Son, Dong-Jun|Kim, Mi-Young|Oak, Chan-Young|Chung, Cho-Yun|Park, Hyung-Chul|Kim, Jong-Sun|Myung, Dae-Seong|Cho, Sung-Bum|Joo, Young-Eun
PMID: 25672320
Journal: Acta Pharmacol Sin. 2015 Dec;36(12):1514-9.
Title: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway.
Author: Su, Li-ya|Shi, Ying-xu|Yan, Mei-rong|Xi, Yaguang|Su, Xiu-lan
PMID: 26592508
Journal: Biomed Res Int. 2015;2015:365273.
Title: miR-125b Suppresses Proliferation and Invasion by Targeting MCL1 in Gastric Cancer.
Author: Wu, Shihua|Liu, Feng|Xie, Liming|Peng, Yaling|Lv, Xiaoyuan|Zhu, Yaping|Zhang, Zhiwei|He, Xiusheng
PMID: 26504803
Journal: Cancer Lett. 2015 Dec 1;369(1):58-66.
Title: Identification of miRNomes in human stomach and gastric carcinoma reveals miR-133b/a-3p as therapeutic target for gastric cancer.
Author: Liu, Yanfang|Zhang, Xin|Zhang, Yujing|Hu, Zunqi|Yang, Dejun|Wang, Changming|Guo, Meng|Cai, Qingping
PMID: 26276722
Journal: Hepatogastroenterology. 2015 Mar-Apr;62(138):540-5.
Title: Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer.
Author: Ikeo, Koichi|Oshima, Tadayuki|Shan, Jing|Matsui, Hirofumi|Tomita, Toshihiko|Fukui, Hirokazu|Watari, Jiro|Miwa, Hiroto
PMID: 25916097
Journal: Cell Biochem Biophys. 2015 May;72(1):241-9.
Title: Kurarinone Synergizes TRAIL-Induced Apoptosis in Gastric Cancer Cells.
Author: Zhou, Wenchao|Cao, Aili|Wang, Li|Wu, Dazheng
PMID: 25524636
Journal: Free Radic Biol Med. 2015 Feb;79:127-37.
Title: MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-kappaB/Snail/Bcl-2 pathway.
Author: Chen, Po-Ming|Cheng, Ya-Wen|Wu, Tzu-Chin|Chen, Chih-Yi|Lee, Huei
PMID: 25499851
Journal: Tumour Biol. 2015 Dec;36(12):9537-44.
Title: Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil.
Author: Chen, Wei-Yu|Huang, Chien-Yu|Cheng, Wan-Li|Hung, Chin-Sheng|Huang, Ming-Te|Tai, Cheng-Jeng|Liu, Yen-Nien|Chen, Chi-Long|Chang, Yu-Jia
PMID: 26136123
Journal: Pharm Biol. 2016;54(2):285-92.
Title: Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo.
Author: Zhu, Haitao|Zheng, Zhichao|Zhang, Jianjun|Liu, Xiaoping|Liu, Yang|Yang, Wei|Liu, Yong|Zhang, Tao|Zhao, Yan|Liu, Yanqing|Su, Xiaohui|Gu, Xiaohu
PMID: 25853970
Journal: Tumour Biol. 2016 Jul;37(7):9493-501.
Title: Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment.
Author: Tu, Chao-Chiang|Huang, Chien-Yu|Cheng, Wan-Li|Hung, Chin-Sheng|Chang, Yu-Jia|Wei, Po-Li
PMID: 26790437
Journal: Tumour Biol. 2016 Aug;37(8):10269-78.
Title: Trichostatin A potentiates TRAIL-induced antitumor effects via inhibition of ERK/FOXM1 pathway in gastric cancer.
Author: Li, Lin|Fan, Biao|Zhang, Lian-Hai|Xing, Xiao-Fang|Cheng, Xiao-Jing|Wang, Xiao-Hong|Guo, Ting|Du, Hong|Wen, Xian-Zi|Ji, Jia-Fu
PMID: 26831669
Journal: Oncol Rep. 2016 May;35(5):3009-17.
Title: Paclitaxel enhances tumoricidal potential of TRAIL via inhibition of MAPK in resistant gastric cancer cells.
Author: Li, Lin|Wen, Xian-Zi|Bu, Zhao-De|Cheng, Xiao-Jing|Xing, Xiao-Fang|Wang, Xiao-Hong|Zhang, Lian-Hai|Guo, Ting|Du, Hong|Hu, Ying|Fan, Biao|Ji, Jia-Fu
PMID: 26986870
Journal: Pharmazie. 2016 Jun;71(6):345-8.
Title: Knockdown of the FoxM1 enhances the sensitivity of gastric cancer cells to cisplatin by targeting Mcl-1.
Author: Li, Xiaomei|Liang, Jun|Liu, Ying-Xun|Wang, Yuming|Yang, Xiao-Hui|Bao-Hongluan|Zhang, Gui-Lling|Du, Juan|Wu, Xia-Hong
PMID: 27455555
Journal: Int J Mol Med. 2016 Nov;38(5):1474-1480.
Title: Trefoil factor family 2 expression inhibits gastric cancer cell growth and invasion in vitro via interactions with the transcription factor Sp3.
Author: Cai, Yiling|Yi, Mengting|Chen, Dajun|Liu, Jingjing|Guleng, Bayasi|Ren, Jianlin|Shi, Huaxiu
PMID: 27668303
Journal: Clin Res Hepatol Gastroenterol. 2017 Dec;41(6):687-692.
Title: Aberrant expression of deubiquitylating enzyme USP9X predicts poor prognosis in gastric cancer.
Author: Fu, Xiang|Xie, Wei|Song, Xiaoxue|Wu, Kun|Xiao, Linkang|Liu, Yongqiang|Zhang, Lei
PMID: 28274596
Journal: Oncotarget. 2017 Sep 13;8(63):106538-106550.
Title: Low plasma levels of miR-101 are associated with tumor progression in gastric cancer.
Author: Imamura, Taisuke|Komatsu, Shuhei|Ichikawa, Daisuke|Miyamae, Mahito|Okajima, Wataru|Ohashi, Takuma|Kiuchi, Jun|Nishibeppu, Keiji|Kosuga, Toshiyuki|Konishi, Hirotaka|Shiozaki, Atsushi|Okamoto, Kazuma|Fujiwara, Hitoshi|Otsuji, Eigo
PMID: 29290969
Journal: Oncotarget. 2017 Aug 12;8(47):82981-82990.
Title: Mcl-1 stabilization confers resistance to taxol in human gastric cancer.
Author: Shuang, Wu|Hou, Lili|Zhu, Yan|Li, Qun|Hu, Wanglai
PMID: 29137317
Journal: Cell Death Dis. 2017 Feb 9;8(2):e2612.
Title: Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1.
Author: Song, Shiyu|Su, Zhonglan|Xu, Hui|Niu, Mengyuan|Chen, Xiufang|Min, Haiyan|Zhang, Bin|Sun, Guibo|Xie, Sijing|Wang, Hongwei|Gao, Qian
PMID: 28182003
Journal: Biochem Biophys Res Commun. 2018 Mar 18;497(4):1177-1183.
Title: Actein enhances TRAIL effects on suppressing gastric cancer progression by activating p53/Caspase-3 signaling.
Author: Yang, Zhi-Chao|Ma, Ji
PMID: 27914809
Journal: Hum Cell. 2018 Jan;31(1):50-63.
Title: Inhibition of two gastric cancer cell lines induced by fucoxanthin involves downregulation of Mcl-1 and STAT3.
Author: Yu, Rui-Xue|Yu, Rui-Tao|Liu, Zhong
PMID: 29110251
Journal: Biosci Rep. 2018 May 8;38(3). pii: BSR20171607.
Title: LINC00152 down-regulated miR-193a-3p to enhance MCL1 expression and promote gastric cancer cells proliferation.
Author: Huang, Yong|Luo, Hui|Li, Fang|Yang, Yun'e|Ou, Guangsheng|Ye, Xiaolong|Li, Nianchu
PMID: 29339419
Journal: J Hematol Oncol. 2018 Mar 20;11(1):43.
Title: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma.
Author: Shi, Cunzhen|Li, Xiangqun|Wang, Xiaogan|Ding, Ning|Ping, Lingyan|Shi, Yunfei|Mi, Lan|Lai, Yumei|Song, Yuqin|Zhu, Jun
PMID: 29554921
Journal: Mar Drugs. 2018 Mar 26;16(4). pii: md16040104.
Title: 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2alpha/ATF4/CHOP Signaling Pathway.
Author: Tsai, Tsung-Chang|Lai, Kuei-Hung|Su, Jui-Hsin|Wu, Yu-Jen|Sheu, Jyh-Horng
PMID: 29587440
Journal: Environ Toxicol. 2018 Aug 27.
Title: Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells.
Author: Shang, Hung-Sheng|Lu, Hsu-Feng|Lee, Ching-Hsiao|Chiang, Han-Sun|Chu, Yung-Lin|Chen, Ann|Lin, Yuh-Feng|Chung, Jing-Gung
PMID: 30152185
Journal: Onco Targets Ther. 2018 Oct 5;11:6579-6587.
Title: Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling.
Author: Huang, Ziming|Cai, Yong|Yang, Chenchen|Chen, Zhen|Sun, Hong|Xu, Yingying|Chen, Wei|Xu, Dafu|Tian, Wenze|Wang, Haixiao
PMID: 30323630
Journal: Front Pharmacol. 2018 Oct 17;9:1197.
Title: XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells.
Author: Pajuelo-Lozano, Natalia|Bargiela-Iparraguirre, Jone|Dominguez, Gemma|Quiroga, Adoracion G|Perona, Rosario|Sanchez-Perez, Isabel
PMID: 30386247