Primary Site >> Stomach Cancer
Gene >> MCL1
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Ref: Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach. PMID: 8909234 |
Ref: IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1. PMID: 11751424 |
Ref: Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells. PMID: 16969094 Ref: Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. PMID: 17172809 |
Ref: Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. PMID: 17935137 Ref: Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor. PMID: 18719002 |
Ref: Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. PMID: 19503096 |
Ref: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion. PMID: 20712078 |
Ref: Low-dose taxotere enhances the ability of sorafenib to induce apoptosis in gastric cancer models. PMID: 20015197 Ref: Citrate induces apoptotic cell death: a promising way to treat gastric carcinoma? PMID: 21498699 Ref: Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop. PMID: 21826665 |
Ref: Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1. PMID: 22108005 Ref: The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis. PMID: 22294184 Ref: MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors. PMID: 22456335 Ref: Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells. PMID: 24213508 |
Ref: The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells. PMID: 23001726 Ref: Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1. PMID: 24136787 |
Ref: Inhibition of MEK sensitizes gastric cancer cells to TRAIL-induced apoptosis. PMID: 24299309 Ref: Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study. PMID: 24643999 Ref: Silibinin inhibits proliferation, induces apoptosis and causes cell cycle arrest in human gastric cancer MGC803 cells via STAT3 pathway inhibition. PMID: 25169527 Ref: Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl1 and BclxL and increasing Bax and CHOP protein expression. PMID: 25270224 Ref: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression. PMID: 25342459 |
Ref: MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-kappaB/Snail/Bcl-2 pathway. PMID: 25499851 Ref: Kurarinone Synergizes TRAIL-Induced Apoptosis in Gastric Cancer Cells. PMID: 25524636 Ref: Myeloid cell leukemia-1 regulates the cell growth and predicts prognosis in gastric cancer. PMID: 25672320 Ref: Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer. PMID: 25916097 Ref: Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil. PMID: 26136123 Ref: Identification of miRNomes in human stomach and gastric carcinoma reveals miR-133b/a-3p as therapeutic target for gastric cancer. PMID: 26276722 Ref: miR-125b Suppresses Proliferation and Invasion by Targeting MCL1 in Gastric Cancer. PMID: 26504803 Ref: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway. PMID: 26592508 |
Ref: Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo. PMID: 25853970 Ref: Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment. PMID: 26790437 Ref: Trichostatin A potentiates TRAIL-induced antitumor effects via inhibition of ERK/FOXM1 pathway in gastric cancer. PMID: 26831669 Ref: Paclitaxel enhances tumoricidal potential of TRAIL via inhibition of MAPK in resistant gastric cancer cells. PMID: 26986870 Ref: Knockdown of the FoxM1 enhances the sensitivity of gastric cancer cells to cisplatin by targeting Mcl-1. PMID: 27455555 Ref: Trefoil factor family 2 expression inhibits gastric cancer cell growth and invasion in vitro via interactions with the transcription factor Sp3. PMID: 27668303 |
Ref: Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1. PMID: 28182003 Ref: Aberrant expression of deubiquitylating enzyme USP9X predicts poor prognosis in gastric cancer. PMID: 28274596 Ref: Mcl-1 stabilization confers resistance to taxol in human gastric cancer. PMID: 29137317 Ref: Low plasma levels of miR-101 are associated with tumor progression in gastric cancer. PMID: 29290969 |
Ref: Actein enhances TRAIL effects on suppressing gastric cancer progression by activating p53/Caspase-3 signaling. PMID: 27914809 Ref: Inhibition of two gastric cancer cell lines induced by fucoxanthin involves downregulation of Mcl-1 and STAT3. PMID: 29110251 Ref: LINC00152 down-regulated miR-193a-3p to enhance MCL1 expression and promote gastric cancer cells proliferation. PMID: 29339419 Ref: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma. PMID: 29554921 Ref: 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2alpha/ATF4/CHOP Signaling Pathway. PMID: 29587440 Ref: Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells. PMID: 30152185 Ref: Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling. PMID: 30323630 Ref: XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells. PMID: 30386247 |