Primary Site >> Colorectal Cancer
Gene >> MBD4
| 1. | |||||||||||
| Journal: | Oncogene. 1999 Dec 23;18(56):8044-7. | ||||||||||
| Title: | Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. | ||||||||||
| Author: | Bader, S|Walker, M|Hendrich, B|Bird, A|Bird, C|Hooper, M|Wyllie, A | ||||||||||
| PMID: | 10637515 | ||||||||||
| 2. | |||||||||||
| Journal: | Am J Pathol. 2000 Aug;157(2):347-52. | ||||||||||
| Title: | Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer. | ||||||||||
| Author: | Loukola, A|Vilkki, S|Singh, J|Launonen, V|Aaltonen, L A | ||||||||||
| PMID: | 10934138 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2001 Aug 23;20(37):5215-8. | ||||||||||
| Title: | Alterations of repeated sequences in 5' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome. | ||||||||||
| Author: | Miyaki, M|Iijima, T|Shiba, K|Aki, T|Kita, Y|Yasuno, M|Mori, T|Kuroki, T|Iwama, T | ||||||||||
| PMID: | 11526511 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Lett. 2002 Jul 8;181(1):115-20. | ||||||||||
| Title: | Frameshift mutations in the MBD4/MED1 gene in primary gastric cancer with high-frequency microsatellite instability. | ||||||||||
| Author: | Yamada, Tatsuya|Koyama, Toru|Ohwada, Susumu|Tago, Ken-ichi|Sakamoto, Ichiro|Yoshimura, Sumihiko|Hamada, Kunihiro|Takeyoshi, Izumi|Morishita, Yasuo | ||||||||||
| PMID: | 12430186 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2003 Feb 15;63(4):787-92. | ||||||||||
| Title: | Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer. | ||||||||||
| Author: | Ricciardiello, Luigi|Goel, Ajay|Mantovani, Vilma|Fiorini, Tania|Fossi, Stefania|Chang, Dong K|Lunedei, Veronica|Pozzato, Paolo|Zagari, Rocco M|De Luca, Luca|Fuccio, Lorenzo|Martinelli, Giuseppe N|Roda, Enrico|Boland, C Richard|Bazzoli, Franco | ||||||||||
| PMID: | 12591727 | ||||||||||
| 6. | |||||||||||
| Journal: | Anticancer Res. 2003 Jul-Aug;23(4):3569-74. | ||||||||||
| Title: | Microsatellite instability and MBD4 mutation in unselected colorectal cancer. | ||||||||||
| Author: | Evertson, Sofia|Wallin, Asa|Arbman, Gunnar|Rutten, Sabine|Emterling, Anna|Zhang, Hong|Sun, Xiao-Feng | ||||||||||
| PMID: | 12926109 | ||||||||||
| 7. | |||||||||||
| Journal: | Dis Colon Rectum. 2006 Mar;49(3):399-406. | ||||||||||
| Title: | Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer. | ||||||||||
| Author: | Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko | ||||||||||
| PMID: | 16421660 | ||||||||||
| 8. | |||||||||||
| Journal: | Gastroenterology. 2006 Jul;131(1):30-9. | ||||||||||
| Title: | Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH. | ||||||||||
| Author: | Chow, Elizabeth|Lipton, Lara|Lynch, Elly|D'Souza, Rebecca|Aragona, Clelia|Hodgkin, Lindy|Brown, Gregor|Winship, Ingrid|Barker, Melissa|Buchanan, Daniel|Cowie, Shannon|Nasioulas, Steve|du Sart, Desiree|Young, Joanne|Leggett, Barbara|Jass, Jeremy|Macrae, Fi | ||||||||||
| PMID: | 16831587 | ||||||||||
| 9. | |||||||||||
| Journal: | Br J Cancer. 2007 Feb 26;96(4):660-6. Epub 2007 Feb 6. | ||||||||||
| Title: | A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells. | ||||||||||
| Author: | Bader, S A|Walker, M|Harrison, D J | ||||||||||
| PMID: | 17285135 | ||||||||||
| 10. | |||||||||||
| Journal: | DNA Repair (Amst). 2008 Feb 1;7(2):321-8. Epub 2007 Dec 26. | ||||||||||
| Title: | Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells. | ||||||||||
| Author: | Abdel-Rahman, Wael M|Knuutila, Sakari|Peltomaki, Paivi|Harrison, David J|Bader, Scott A | ||||||||||
| PMID: | 18162445 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncol Rep. 2008 Jan;19(1):257-62. | ||||||||||
| Title: | Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer. | ||||||||||
| Author: | Xi, Yaguang|Formentini, Andrea|Nakajima, Go|Kornmann, Marko|Ju, Jingfang | ||||||||||
| PMID: | 18097604 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Biol Ther. 2009 Jan;8(1):94-100. Epub 2009 Jan 20. | ||||||||||
| Title: | Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer. | ||||||||||
| Author: | Howard, J Harrison|Frolov, Andrey|Tzeng, Ching-Wei D|Stewart, Ashley|Midzak, Andrew|Majmundar, Amar|Godwin, Andrew|Heslin, Martin|Bellacosa, Alfonso|Arnoletti, J Pablo | ||||||||||
| PMID: | 19127118 | ||||||||||
| 13. | |||||||||||
| Journal: | Neoplasma. 2009;56(4):343-7. | ||||||||||
| Title: | The Glu346Lys polymorphism and frameshift mutations of the Methyl-CpG Binding Domain 4 gene in gastrointestinal cancer. | ||||||||||
| Author: | Song, J H|Maeng, E J|Cao, Z|Kim, S Y|Nam, S W|Lee, J Y|Park, W S | ||||||||||
| PMID: | 19469655 | ||||||||||
| 14. | |||||||||||
| Journal: | Int J Oncol. 2009 Nov;35(5):977-82. | ||||||||||
| Title: | Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer. | ||||||||||
| Author: | Kawaguchi, Makiko|Banno, Kouji|Yanokura, Megumi|Kobayashi, Yusuke|Kishimi, Arisa|Ogawa, Seiji|Kisu, Iori|Nomura, Hiroyuki|Hirasawa, Akira|Susumu, Nobuyuki|Aoki, Daisuke | ||||||||||
| PMID: | 19787250 | ||||||||||
| 15. | |||||||||||
| Journal: | DNA Repair (Amst). 2012 Jul 1;11(7):616-23. | ||||||||||
| Title: | Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency. | ||||||||||
| Author: | Vasovcak, P|Krepelova, A|Menigatti, M|Puchmajerova, A|Skapa, P|Augustinakova, A|Amann, G|Wernstedt, A|Jiricny, J|Marra, G|Wimmer, K | ||||||||||
| PMID: | 22608206 | ||||||||||
| 16. | |||||||||||
| Journal: | Mutat Res. 2013 Jul-Aug;747-748:19-27. | ||||||||||
| Title: | Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity. | ||||||||||
| Author: | Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Carethers, John M | ||||||||||
| PMID: | 23643670 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2015 Dec 15;6(40):42892-904. | ||||||||||
| Title: | Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis. | ||||||||||
| Author: | Tricarico, Rossella|Cortellino, Salvatore|Riccio, Antonio|Jagmohan-Changur, Shantie|Van der Klift, Heleen|Wijnen, Juul|Turner, David|Ventura, Andrea|Rovella, Valentina|Percesepe, Antonio|Lucci-Cordisco, Emanuela|Radice, Paolo|Bertario, Lucio|Pedroni, Moni | ||||||||||
| PMID: | 26503472 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncotarget. 2016 May 10;7(19):28624-36. | ||||||||||
| Title: | The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury. | ||||||||||
| Author: | Yu, Amy Marie|Calvo, Jennifer A|Muthupalani, Suresh|Samson, Leona D | ||||||||||
| PMID: | 27086921 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Biol Ther. 2016 Jul 2;17(7):760-8. | ||||||||||
| Title: | Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status. | ||||||||||
| Author: | Suzuki, Satoshi|Iwaizumi, Moriya|Tseng-Rogenski, Stephanie|Hamaya, Yasushi|Miyajima, Hiroaki|Kanaoka, Shigeru|Sugimoto, Ken|Carethers, John M | ||||||||||
| PMID: | 27115207 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 15;9(14):11477-11488. | ||||||||||
| Title: | MBD4 frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells. | ||||||||||
| Author: | Suzuki, Satoshi|Iwaizumi, Moriya|Yamada, Hidetaka|Sugiyama, Tomohiro|Hamaya, Yasushi|Furuta, Takahisa|Kanaoka, Shigeru|Sugimura, Haruhiko|Miyajima, Hiroaki|Osawa, Satoshi|Carethers, John M|Sugimoto, Ken | ||||||||||
| PMID: | 29545913 | ||||||||||