Literatures

Primary Site >> Liver Cancer

Gene >> MAT1A

1.
Journal:	Hepatology. 1996 Nov;24(5):1090-7.
Title:	Changes in S-adenosylmethionine synthetase in human liver cancer: molecular characterization and significance.
Author:	Cai, J\|Sun, W M\|Hwang, J J\|Stain, S C\|Lu, S C
PMID:	8903381

2.
Journal:	Eur J Biochem. 1997 Dec 15;250(3):653-60.
Title:	Structure of the rat methionine adenosyltransferase 2A gene and its promoter.
Author:	Hiroki, T\|Horikawa, S\|Tsukada, K
PMID:	9461287

3.
Journal:	Cancer Res. 1998 Apr 1;58(7):1444-50.
Title:	Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells.
Author:	Cai, J\|Mao, Z\|Hwang, J J\|Lu, S C
PMID:	9537246

4.
Journal:	Hepatology. 1999 May;29(5):1471-8.
Title:	Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat.
Author:	Huang, Z Z\|Mato, J M\|Kanel, G\|Lu, S C
PMID:	10216131

5.
Journal:	FASEB J. 2000 Jan;14(1):95-102.
Title:	Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.
Author:	Torres, L\|Avila, M A\|Carretero, M V\|Latasa, M U\|Caballeria, J\|Lopez-Rodas, G\|Boukaba, A\|Lu, S C\|Franco, L\|Mato, J M
PMID:	10627284

6.
Journal:	Biochem J. 2000 Mar 1;346 Pt 2:475-82.
Title:	Cloning and functional characterization of the 5'-flanking region of human methionine adenosyltransferase 1A gene.
Author:	Zeng, Z\|Huang, Z Z\|Chen, C\|Yang, H\|Mao, Z\|Lu, S C
PMID:	10677369

7.
Journal:	J Hepatol. 2000 Dec;33(6):907-14.
Title:	Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
Author:	Avila, M A\|Berasain, C\|Torres, L\|Martin-Duce, A\|Corrales, F J\|Yang, H\|Prieto, J\|Lu, S C\|Caballeria, J\|Rodes, J\|Mato, J M
PMID:	11131452

8.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2001 Feb;280(2):G184-90.
Title:	Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer.
Author:	Yang, H\|Huang, Z Z\|Zeng, Z\|Chen, C\|Selby, R R\|Lu, S C
PMID:	11208539

9.
Journal:	FASEB J. 2001 Jul;15(9):1507-16.
Title:	The role of c-Myb and Sp1 in the up-regulation of methionine adenosyltransferase 2A gene expression in human hepatocellular carcinoma.
Author:	Yang, H\|Huang, Z Z\|Wang, J\|Lu, S C
PMID:	11427482

10.
Journal:	FASEB J. 2002 Aug;16(10):1292-4.
Title:	Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
Author:	Martinez-Chantar, Maria L\|Corrales, Fernando J\|Martinez-Cruz, L Alfonso\|Garcia-Trevijano, Elena R\|Huang, Zong-Zhi\|Chen, Lixin\|Kanel, Gary\|Avila, Matias A\|Mato, Jose M\|Lu, Shelly C
PMID:	12060674

11.
Journal:	Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3065-70.
Title:	Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine.
Author:	Santamaria, Enrique\|Avila, Matias A\|Latasa, M Ujue\|Rubio, Angel\|Martin-Duce, Antonio\|Lu, Shelly C\|Mato, Jose M\|Corrales, Fernando J
PMID:	12631701

12.
Journal:	Gastroenterology. 2003 Apr;124(4):940-8.
Title:	Methionine adenosyltransferase II beta subunit gene expression provides a proliferative advantage in human hepatoma.
Author:	Martinez-Chantar, Maria L\|Garcia-Trevijano, Elena R\|Latasa, M Ujue\|Martin-Duce, Antonio\|Fortes, Puri\|Caballeria, Juan\|Avila, Matias A\|Mato, Jose M
PMID:	12671891

13.
Journal:	J Biol Chem. 2003 Dec 19;278(51):50887-96.
Title:	Induction of human methionine adenosyltransferase 2A expression by tumor necrosis factor alpha. Role of NF-kappa B and AP-1.
Author:	Yang, Heping\|Sadda, Mamatha R\|Yu, Victor\|Zeng, Ying\|Lee, Taunia D\|Ou, Xiaopeng\|Chen, Lixin\|Lu, Shelly C
PMID:	14530285

14.
Journal:	J Clin Invest. 2004 Mar;113(6):895-904.
Title:	Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis.
Author:	Mari, Montserrat\|Colell, Anna\|Morales, Albert\|Paneda, Covadonga\|Varela-Nieto, Isabel\|Garcia-Ruiz, Carmen\|Fernandez-Checa, Jose C
PMID:	15067322

15.
Journal:	J Biol Chem. 2004 Dec 8. pii: M410405200.
Title:	WITHDRAWN: Silencing of human methionine adenosyltransferase 1A expression by methylation of the coding region.
Author:	Li, Mei\|Ou, Xiaopeng\|Lee, Taunia D\|Zeng, Ying\|Mato, Jose M\|Lu, Shelly C
PMID:	15590672

16.
Journal:	FASEB J. 2004 May;18(7):914-6.
Title:	Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.
Author:	Chen, Lixin\|Zeng, Ying\|Yang, Heping\|Lee, Taunia D\|French, Samuel W\|Corrales, Fernando J\|Garcia-Trevijano, Elena R\|Avila, Matias A\|Mato, Jose M\|Lu, Shelly C
PMID:	15033934

17.
Journal:	Carcinogenesis. 2005 Feb;26(2):417-27.
Title:	Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.
Author:	Simile, Maria M\|Pagnan, Gabriella\|Pastorino, Fabio\|Brignole, Chiara\|De Miglio, Maria R\|Muroni, Maria R\|Asara, Giuseppina\|Frau, Maddalena\|Seddaiu, Maria A\|Calvisi, Diego F\|Feo, Francesco\|Ponzoni, Mirco\|Pascale, Rosa M
PMID:	15498786

18.
Journal:	Alcohol. 2005 Apr;35(3):227-34.
Title:	Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
Author:	Lu, Shelly C\|Mato, Jose M
PMID:	16054984

19.
Journal:	Proteomics. 2005 Dec;5(18):4964-72.
Title:	Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.
Author:	Fernandez-Irigoyen, Jokin\|Santamaria, Enrique\|Sesma, Laura\|Munoz, Javier\|Riezu, Jose Ignacio\|Caballeria, Juan\|Lu, Shelly C\|Prieto, Jesus\|Mato, Jose M\|Avila, Matias A\|Corrales, Fernando J
PMID:	16252306

20.
Journal:	J Proteome Res. 2006 Apr;5(4):944-53.
Title:	Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver diseases.
Author:	Santamaria, Enrique\|Munoz, Javier\|Fernandez-Irigoyen, Joaquin\|Sesma, Laura\|Mora, Maria I\|Berasain, Carmen\|Lu, Shelly C\|Mato, Jose M\|Prieto, Jesus\|Avila, Matias A\|Corrales, Fernando J
PMID:	16602702

21.
Journal:	Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6489-94.
Title:	S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
Author:	Prudova, Anna\|Bauman, Zachary\|Braun, Aaron\|Vitvitsky, Victor\|Lu, Shelly C\|Banerjee, Ruma
PMID:	16614071

22.
Journal:	J Cell Physiol. 2007 Mar;210(3):766-73.
Title:	Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells.
Author:	Yang, Heping\|Magilnick, Nathaniel\|Noureddin, Mazen\|Mato, Jose M\|Lu, Shelly C
PMID:	17154373

23.
Journal:	Hepatol Res. 2007 May;37(5):376-88.
Title:	Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.
Author:	Liu, Quanyan\|Wu, Kailang\|Zhu, Ying\|He, Yueming\|Wu, Jianguo\|Liu, Zhisu
PMID:	17441811

24.
Journal:	Rev Recent Clin Trials. 2007 Sep;2(3):217-36.
Title:	Dissection of signal transduction pathways as a tool for the development of targeted therapies of hepatocellular carcinoma.
Author:	Calvisi, Diego F\|Pascale, Rosa M\|Feo, Francesco
PMID:	18474008

25.
Journal:	Biochem Soc Trans. 2008 Oct;36(Pt 5):848-52.
Title:	S-adenosylmethionine and proliferation: new pathways, new targets.
Author:	Martinez-Lopez, Nuria\|Varela-Rey, Marta\|Ariz, Usue\|Embade, Nieves\|Vazquez-Chantada, Mercedes\|Fernandez-Ramos, David\|Gomez-Santos, Laura\|Lu, Shelly C\|Mato, Jose M\|Martinez-Chantar, Maria L
PMID:	18793149

26.
Journal:	J Gastroenterol Hepatol. 2008 Mar;23 Suppl 1:S73-7.
Title:	S-Adenosylmethionine in cell growth, apoptosis and liver cancer.
Author:	Lu, Shelly C\|Mato, Jose M
PMID:	18336669

27.
Journal:	Gastroenterology. 2008 Jan;134(1):281-91.
Title:	Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells.
Author:	Yang, Heping\|Ara, Ainhoa Iglesias\|Magilnick, Nathaniel\|Xia, Meng\|Ramani, Komal\|Chen, Hui\|Lee, Taunia D\|Mato, Jose M\|Lu, Shelly C
PMID:	18045590

28.
Journal:	Hepatology. 2008 Feb;47(2):521-31.
Title:	Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta.
Author:	Ramani, Komal\|Yang, Heping\|Xia, Meng\|Ara, Ainhoa Iglesias\|Mato, Jose M\|Lu, Shelly C
PMID:	18041713

29.
Journal:	Hepatology. 2008 Apr;47(4):1288-97.
Title:	Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A-deficient mice.
Author:	Rountree, C Bart\|Senadheera, Shantha\|Mato, Jose M\|Crooks, Gay M\|Lu, Shelly C
PMID:	18167064

30.
Journal:	Gastroenterology. 2009 Mar;136(3):1025-36.
Title:	S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 stability: implication in hepatocarcinogenesis.
Author:	Tomasi, Maria Lauda\|Iglesias-Ara, Ainhoa\|Yang, Heping\|Ramani, Komal\|Feo, Francesco\|Pascale, Maria Rosa\|Martinez-Chantar, M Luz\|Mato, Jose M\|Lu, Shelly C
PMID:	18983843

31.
Journal:	Hepatology. 2009 Apr;49(4):1277-86.
Title:	CD133+ liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis.
Author:	Ding, Wei\|Mouzaki, Marialena\|You, Hanning\|Laird, Joshua C\|Mato, Jose\|Lu, Shelly C\|Rountree, C Bart
PMID:	19115422

32.
Journal:	Gastroenterology. 2010 May;138(5):1943-53.
Title:	HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Author:	Vazquez-Chantada, Mercedes\|Fernandez-Ramos, David\|Embade, Nieves\|Martinez-Lopez, Nuria\|Varela-Rey, Marta\|Woodhoo, Ashwin\|Luka, Zigmund\|Wagner, Conrad\|Anglim, Paul P\|Finnell, Richard H\|Caballeria, Juan\|Laird-Offringa, Ite A\|Gorospe, Myriam\|Lu, Shelly C\|Mat
PMID:	20102719

33.
Journal:	Am J Pathol. 2010 May;176(5):2456-66.
Title:	Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice.
Author:	Li, Jiaping\|Ramani, Komal\|Sun, Zhanfeng\|Zee, Chishing\|Grant, Edward G\|Yang, Heping\|Xia, Meng\|Oh, Pilsoo\|Ko, Kwangsuk\|Mato, Jose M\|Lu, Shelly C
PMID:	20363925

34.
Journal:	Hepatology. 2010 Nov;52(5):1621-31.
Title:	Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis.
Author:	Martinez-Lopez, Nuria\|Varela-Rey, Marta\|Fernandez-Ramos, David\|Woodhoo, Ashwin\|Vazquez-Chantada, Mercedes\|Embade, Nieves\|Espinosa-Hevia, Luis\|Bustamante, Francisco Javier\|Parada, Luis A\|Rodriguez, Manuel S\|Lu, Shelly C\|Mato, Jose M\|Martinez-Chantar, Maria
PMID:	20815019

35.
Journal:	Hepatology. 2010 Dec;52(6):2096-108.
Title:	Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
Author:	Ko, Kwang Suk\|Tomasi, Maria Lauda\|Iglesias-Ara, Ainhoa\|French, Barbara A\|French, Samuel W\|Ramani, Komal\|Lozano, Juan Jose\|Oh, Pilsoo\|He, Lina\|Stiles, Bangyan L\|Li, Tony W H\|Yang, Heping\|Martinez-Chantar, M Luz\|Mato, Jose M\|Lu, Shelly C
PMID:	20890892

36.
Journal:	J Biol Chem. 2011 May 13;286(19):17168-80.
Title:	The X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production.
Author:	Liu, Quanyan\|Chen, Jiwei\|Liu, Li\|Zhang, Jun\|Wang, Dongfeng\|Ma, Lu\|He, Yueming\|Liu, Yingle\|Liu, Zhisu\|Wu, Jianguo
PMID:	21247894

37.
Journal:	J Cell Physiol. 2012 Apr;227(4):1583-91.
Title:	Inhibition of human methionine adenosyltransferase 1A transcription by coding region methylation.
Author:	Tomasi, Maria Lauda\|Li, Tony W H\|Li, Mei\|Mato, Jose M\|Lu, Shelly C
PMID:	21678410

38.
Journal:	J Proteomics. 2012 Jun 6;75(10):2855-68.
Title:	Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III: Characterization of DDX3X as a target of S-adenosylmethionine.
Author:	Schroder, Paul C\|Fernandez-Irigoyen, Joaquin\|Bigaud, Emilie\|Serna, Antonio\|Renandez-Alcoceba, Ruben\|Lu, Shelly C\|Mato, Jose M\|Prieto, Jesus\|Corrales, Fernando J
PMID:	22270009

39.
Journal:	Hepatology. 2012 Jul;56(1):165-75.
Title:	Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.
Author:	Frau, Maddalena\|Tomasi, Maria L\|Simile, Maria M\|Demartis, Maria I\|Salis, Fabiana\|Latte, Gavinella\|Calvisi, Diego F\|Seddaiu, Maria A\|Daino, Lucia\|Feo, Claudio F\|Brozzetti, Stefania\|Solinas, Giuliana\|Yamashita, Satoshi\|Ushijima, Toshikazu\|Feo, Francesco\|Pas
PMID:	22318685

40.
Journal:	Physiol Rev. 2012 Oct;92(4):1515-42.
Title:	S-adenosylmethionine in liver health, injury, and cancer.
Author:	Lu, Shelly C\|Mato, Jose M
PMID:	23073625

41.
Journal:	Exp Cell Res. 2013 Jul 15;319(12):1902-11.
Title:	Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Author:	Tomasi, Maria Lauda\|Ryoo, Minjung\|Skay, Anna\|Tomasi, Ivan\|Giordano, Pasquale\|Mato, Jose M\|Lu, Shelly C
PMID:	23588207

42.
Journal:	Asian Pac J Cancer Prev. 2013;14(11):6433-8.
Title:	5-Aza-2<-deoxycytidine induces hepatoma cell apoptosis via enhancing methionine adenosyltransferase 1A expression and inducing S-adenosylmethionine production.
Author:	Liu, Wei-Jun\|Ren, Jian-Guo\|Li, Ting\|Yu, Guo-Zheng\|Zhang, Jin\|Li, Chang-Sheng\|Liu, Zhi-Su\|Liu, Quan-Yan
PMID:	24377546

43.
Journal:	PLoS One. 2013 Sep 30;8(9):e75628.
Title:	MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth.
Author:	Lo, Ting-Fang\|Tsai, Wei-Chung\|Chen, Shui-Tein
PMID:	24098708

44.
Journal:	J Hepatol. 2013 Oct;59(4):830-41.
Title:	Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Author:	Frau, Maddalena\|Feo, Francesco\|Pascale, Rosa M
PMID:	23665184

45.
Journal:	IUCrJ. 2014 Jun 12;1(Pt 4):240-9.
Title:	Structure and function study of the complex that synthesizes S-adenosylmethionine.
Author:	Murray, Ben\|Antonyuk, Svetlana V\|Marina, Alberto\|Van Liempd, Sebastiaan M\|Lu, Shelly C\|Mato, Jose M\|Hasnain, S Samar\|Rojas, Adriana L
PMID:	25075345

46.
Journal:	J Hepatocell Carcinoma. 2014 Jun 12;1:65-83.
Title:	New insights on the role of epigenetic alterations in hepatocellular carcinoma.
Author:	Frau, Maddalena\|Feo, Claudio F\|Feo, Francesco\|Pascale, Rosa M
PMID:	27508177

47.
Journal:	Hepatology. 2016 Aug;64(2):439-55.
Title:	Deregulated methionine adenosyltransferase alpha1, c-Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans(double dagger).
Author:	Yang, Heping\|Liu, Ting\|Wang, Jiaohong\|Li, Tony W H\|Fan, Wei\|Peng, Hui\|Krishnan, Anuradha\|Gores, Gregory J\|Mato, Jose M\|Lu, Shelly C
PMID:	26969892

48.
Journal:	Hepatology. 2017 Apr;65(4):1249-1266.
Title:	Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells.
Author:	Fan, Wei\|Yang, Heping\|Liu, Ting\|Wang, Jiaohong\|Li, Tony W H\|Mavila, Nirmala\|Tang, Yuanyuan\|Yang, JinWon\|Peng, Hui\|Tu, Jian\|Annamalai, Alagappan\|Noureddin, Mazen\|Krishnan, Anuradha\|Gores, Gregory J\|Martinez-Chantar, Maria L\|Mato, Jose M\|Lu, Shelly C
PMID:	27981602

49.
Journal:	Oncotarget. 2017 May 30;8(62):104772-104784.
Title:	Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity.
Author:	Stoyanov, Evgeniy\|Mizrahi, Lina\|Olam, Devorah\|Schnitzer-Perlman, Temima\|Galun, Eithan\|Goldenberg, Daniel S
PMID:	29285212

50.
Journal:	Exp Biol Med (Maywood). 2018 Jan;243(2):107-117.
Title:	Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy.
Author:	Maldonado, Lauren Y\|Arsene, Diana\|Mato, Jose M\|Lu, Shelly C
PMID:	29141455

51.
Journal:	J Surg Oncol. 2018 Apr;117(5):892-901.
Title:	Histological expression of methionine adenosyl transferase (MAT) 2A as a post-surgical prognostic surrogate in patients with hepatocellular carcinoma.
Author:	An, Jihyun\|Na, Seong Kyun\|Shim, Ju Hyun\|Park, Yang Soon\|Jun, Mi Jung\|Lee, Joo Ho\|Song, Gi-Won\|Lee, Hac Chu\|Yu, Eunsil
PMID:	29448301

52.
Journal:	Gastroenterology. 2018 Aug;155(2):557-571.e14.
Title:	Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.
Author:	Liu, Ting\|Yang, Heping\|Fan, Wei\|Tu, Jian\|Li, Tony W H\|Wang, Jiaohong\|Shen, Hong\|Yang, JinWon\|Xiong, Ting\|Steggerda, Justin\|Liu, Zhenqiu\|Noureddin, Mazen\|Maldonado, Stephanie S\|Annamalai, Alagappan\|Seki, Ekihiro\|Mato, Jose M\|Lu, Shelly C
PMID:	29733835

53.
Journal:	Mol Carcinog. 2018 Sep;57(9):1201-1212.
Title:	A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.
Author:	Wang, Ruizhi\|Jin, Yi\|Yao, Xue-Hua\|Fan, Wenzhe\|Zhang, Jiang\|Cao, Yihai\|Li, Jiaping
PMID:	29749642

54.
Journal:	Cancer Res. 2018 Jul 15;78(14):3849-3864.
Title:	SNHG6 Acts as a Genome-Wide Hypomethylation Trigger via Coupling of miR-1297-Mediated S-Adenosylmethionine-Dependent Positive Feedback Loops.
Author:	Guo, Tao\|Wang, Hongling\|Liu, Pengpeng\|Xiao, Yushao\|Wu, Ping\|Wang, Yitao\|Chen, Baiyang\|Zhao, Qiu\|Liu, Zhisu\|Liu, Quanyan
PMID:	29844127

55.
Journal:	Transl Gastroenterol Hepatol. 2018 Jun 29;3:36.
Title:	Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma.
Author:	Pascale, Rosa M\|Feo, Claudio F\|Calvisi, Diego F\|Feo, Francesco
PMID:	30050996