Primary Site >> Colorectal Cancer

Gene >> MAPKAPK2

Journal: Mol Cancer Ther. 2004 Jun;3(6):755-62.
Title: Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.
Author: Mallon, Robert|Feldberg, Larry|Kim, Steven|Collins, Karen|Wojciechowicz, Donald|Kohler, Constance|Kovacs, Diana|Discafani, Carolyn|Zhang, Nan|Wu, Biqi|Floyd, Brawner|Powell, Dennis|Berger, Dan
PMID: 15210862
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G719-28. Epub 2007 Jul
Title: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts.
Author: Di Mari, J F|Saada, J I|Mifflin, R C|Valentich, J D|Powell, D W
PMID: 17640979
Journal: Virol J. 2008 Nov 12;5:138.
Title: Plaque assay for human coronavirus NL63 using human colon carcinoma cells.
Author: Herzog, Petra|Drosten, Christian|Muller, Marcel A
PMID: 19014487
Journal: PLoS Comput Biol. 2009 Apr;5(4):e1000340.
Title: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.
Author: Aldridge, Bree B|Saez-Rodriguez, Julio|Muhlich, Jeremy L|Sorger, Peter K|Lauffenburger, Douglas A
PMID: 19343194
Journal: PLoS One. 2012;7(11):e49605.
Title: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
Author: Lin, Shih-Pei|Lee, Yi-Ting|Wang, Jir-You|Miller, Stephanie A|Chiou, Shih-Hwa|Hung, Mien-Chie|Hung, Shih-Chieh
PMID: 23185379
Journal: Genes Cancer. 2012 Jul;3(7-8):521-30.
Title: MK2 Regulates Ras Oncogenesis through Stimulating ROS Production.
Author: Kobayashi, Yusuke|Qi, Xiaomei|Chen, Guan
PMID: 23264852
Journal: Cancer Lett. 2013 Jan 28;328(2):226-34.
Title: Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis.
Author: Lin, Shih-Pei|Lee, Yi-Ting|Yang, Shung-Haur|Miller, Stephanie A|Chiou, Shih-Hwa|Hung, Mien-Chie|Hung, Shih-Chieh
PMID: 23017941
Journal: Int J Cancer. 2016 Feb 1;138(3):770-5.
Title: Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
Author: Ray, Anita L|Castillo, Eliseo F|Morris, Katherine T|Nofchissey, Robert A|Weston, Lea L|Samedi, Von G|Hanson, Joshua A|Gaestel, Matthias|Pinchuk, Irina V|Beswick, Ellen J
PMID: 26238259
Journal: Macrophage (Houst). 2016;3.
Title: MK2: an unrecognized regulator of tumor promoting macrophages in colorectal cancer?
Author: Castillo, Eliseo F|Ray, Anita L|Beswick, Ellen J
PMID: 26998523
Journal: Int J Cancer. 2018 Apr 15;142(8):1702-1711.
Title: Inhibition of MK2 suppresses IL-1beta, IL-6, and TNF-alpha-dependent colorectal cancer growth.
Author: Ray, Anita L|Berggren, Kiersten L|Restrepo Cruz, Sebastian|Gan, Gregory N|Beswick, Ellen J
PMID: 29197088
Journal: Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4236-E4244.
Title: MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
Author: Suarez-Lopez, Lucia|Sriram, Ganapathy|Kong, Yi Wen|Morandell, Sandra|Merrick, Karl A|Hernandez, Yuliana|Haigis, Kevin M|Yaffe, Michael B
PMID: 29666270
Journal: Front Immunol. 2018 Sep 21;9:1857.
Title: MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth.
Author: Phinney, Brandon B|Ray, Anita L|Peretti, Amanda S|Jerman, Stephanie J|Grim, Carl|Pinchuk, Irina V|Beswick, Ellen J
PMID: 30298062
Journal: Arch Med Res. 2018 Oct 9. pii: S0188-4409(18)30568-X.
Title: Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line.
Author: Nafees, Sana|Mehdi, Syed Hassan|Zafaryab, Mohammad|Zeya, Bushra|Sarwar, Tarique|Rizvi, Moshahid Alam
PMID: 30314650