Primary Site >> Colorectal Cancer

Gene >> MAPKAPK2

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Ref: Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.
PMID: 15210862
 Ref: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
PMID: 15774489
 Ref: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts.
PMID: 17640979
 Ref: Plaque assay for human coronavirus NL63 using human colon carcinoma cells.
PMID: 19014487
 Ref: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.
PMID: 19343194
 Ref: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
PMID: 23185379
Ref: MK2 Regulates Ras Oncogenesis through Stimulating ROS Production.
PMID: 23264852
 Ref: Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis.
PMID: 23017941
 Ref: Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
PMID: 26238259
Ref: MK2: an unrecognized regulator of tumor promoting macrophages in colorectal cancer?
PMID: 26998523
 Ref: Inhibition of MK2 suppresses IL-1beta, IL-6, and TNF-alpha-dependent colorectal cancer growth.
PMID: 29197088
Ref: MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
PMID: 29666270
Ref: MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth.
PMID: 30298062
Ref: Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line.
PMID: 30314650