Primary Site >> Colorectal Cancer

Gene >> MAPK8

Journal: Gastroenterology. 1997 Nov;113(5):1589-98.
Title: In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia.
Author: Licato, L L|Keku, T O|Wurzelmann, J I|Murray, S C|Woosley, J T|Sandler, R S|Brenner, D A
PMID: 9352861
Journal: Cancer Res. 1997 Nov 1;57(21):4714-7.
Title: Activated Ki-ras enhances sensitivity of ceramide-induced apoptosis without c-Jun NH2-terminal kinase/stress-activated protein kinase or extracellular signal-regulated kinase activation in human colon cancer cells.
Author: Ohmori, M|Shirasawa, S|Furuse, M|Okumura, K|Sasazuki, T
PMID: 9354428
Journal: Oncogene. 1997 Nov 27;15(22):2705-16.
Title: ErbB kinases and NDF signaling in human prostate cancer cells.
Author: Grasso, A W|Wen, D|Miller, C M|Rhim, J S|Pretlow, T G|Kung, H J
PMID: 9400997
Journal: Cancer Res. 1998 Jun 1;58(11):2339-42.
Title: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
Author: Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E
PMID: 9622070
Journal: Dig Dis Sci. 1998 Jul;43(7):1454-64.
Title: Analysis of signaling protein kinases in human colon or colorectal carcinomas.
Author: Licato, L L|Brenner, D A
PMID: 9690379
Journal: Oncogene. 1999 Mar 11;18(10):1807-17.
Title: Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
Author: Plattner, R|Gupta, S|Khosravi-Far, R|Sato, K Y|Perucho, M|Der, C J|Stanbridge, E J
PMID: 10086335
Journal: Cancer Res. 1999 May 15;59(10):2445-50.
Title: Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
Author: Okumura, K|Shirasawa, S|Nishioka, M|Sasazuki, T
PMID: 10344756
Journal: J Biol Chem. 1999 Dec 10;274(50):35505-13.
Title: 1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation.
Author: Chen, A|Davis, B H|Bissonnette, M|Scaglione-Sewell, B|Brasitus, T A
PMID: 10585423
Journal: Br J Cancer. 2000 Jun;82(12):1991-9.
Title: Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c-jun N-terminal kinase activity.
Author: Liu, B|Fang, M|Schmidt, M|Lu, Y|Mendelsohn, J|Fan, Z
PMID: 10864208
Journal: Biochem J. 2000 Dec 1;352 Pt 2:419-24.
Title: Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.
Author: McGinty, A|Foschi, M|Chang, Y W|Han, J|Dunn, M J|Sorokin, A
PMID: 11085935
Journal: FASEB J. 2001 Feb;15(2):362-72.
Title: PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.
Author: Ilan, N|Mohsenin, A|Cheung, L|Madri, J A
PMID: 11156952
Journal: Carcinogenesis. 2001 Jan;22(1):35-41.
Title: Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis.
Author: Qiao, D|Stratagouleas, E D|Martinez, J D
PMID: 11159738
Journal: Gastroenterology. 2001 Jan;120(1):71-8.
Title: Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells.
Author: Mandal, M|Olson, D J|Sharma, T|Vadlamudi, R K|Kumar, R
PMID: 11208715
Journal: J Biol Chem. 2001 May 11;276(19):16406-10. Epub 2001 Mar 14.
Title: Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.
Author: Soh, J W|Mao, Y|Liu, L|Thompson, W J|Pamukcu, R|Weinstein, I B
PMID: 11278263
Journal: Oncogene. 2001 Feb 15;20(7):819-27.
Title: NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps.
Author: Hardwick, J C|van den Brink, G R|Offerhaus, G J|van Deventer, S J|Peppelenbosch, M P
PMID: 11314016
Journal: Biochem Biophys Res Commun. 2001 Jun 8;284(2):282-8.
Title: Alterations of MAPK activities associated with intestinal cell differentiation.
Author: Ding, Q|Wang, Q|Evers, B M
PMID: 11394874
Journal: Int J Oncol. 2001 Sep;19(3):613-6.
Title: DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells.
Author: Jaiswal, A S|Narayan, S
PMID: 11494044
Journal: Angiogenesis. 2001;4(2):155-62.
Title: Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway.
Author: Jung, Y D|Liu, W|Reinmuth, N|Ahmad, S A|Fan, F|Gallick, G E|Ellis, L M
PMID: 11806247
Journal: J Biol Chem. 2002 Feb 1;277(5):3487-97. Epub 2001 Nov 8.
Title: Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release.
Author: Kuwabara, Ichiro|Kuwabara, Yasuko|Yang, Ri-Yao|Schuler, Martin|Green, Douglas R|Zuraw, Bruce L|Hsu, Daniel K|Liu, Fu-Tong
PMID: 11706006
Journal: Int J Oncol. 2002 Apr;20(4):777-83.
Title: Expression of WRCH1 in human cancer and down-regulation of WRCH1 by beta-estradiol in MCF-7 cells.
Author: Kirikoshi, Hiroyuki|Katoh, Masaru
PMID: 11894124
Journal: Gastroenterology. 2002 Apr;122(4):985-93.
Title: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
Author: Yoon, Jung-Hwan|Higuchi, Hajime|Werneburg, Nathan W|Kaufmann, Scott H|Gores, Gregory J
PMID: 11910351
Journal: Int J Oncol. 2002 May;20(5):977-82.
Title: Molecular cloning and characterization of WRCH2 on human chromosome 15q15.
Author: Katoh, Masaru
PMID: 11956592
Journal: Int J Mol Med. 2002 May;9(5):515-9.
Title: Frequent up-regulation of WNT5A mRNA in primary gastric cancer.
Author: Saitoh, Tetsuroh|Mine, Tetsuya|Katoh, Masaru
PMID: 11956659
Journal: Int J Cancer. 2002 May 20;99(3):323-7.
Title: The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells.
Author: Elder, Douglas J E|Halton, Dawn E|Playle, Laura C|Paraskeva, Christos
PMID: 11992399
Journal: Mol Carcinog. 2002 Sep;35(1):21-8.
Title: Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Author: Lin, Shyr-Yi|Liang, Yu-Chih|Ho, Yuan-Soon|Tsai, Shu-Huei|Pan, Shiann|Lee, Wen-Sen
PMID: 12203364
Journal: FASEB J. 2002 Oct;16(12):1642-4.
Title: Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice.
Author: Guerrero, Silvia|Figueras, Agnes|Casanova, Isolda|Farre, Lourdes|Lloveras, Belen|Capella, Gabriel|Trias, Manuel|Mangues, Ramon
PMID: 12207005
Journal: J Biol Chem. 2002 Nov 15;277(46):43648-58. Epub 2002 Sep 6.
Title: Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.
Author: Zhang, Hong|Shi, Xiaoqing|Zhang, Qian-Jin|Hampong, Maggie|Paddon, Harry|Wahyuningsih, Dewi|Pelech, Steven
PMID: 12221076
Journal: J Nutr. 2002 Sep;132(9):2814-8.
Title: Red wine polyphenols inhibit the growth of colon carcinoma cells and modulate the activation pattern of mitogen-activated protein kinases.
Author: Briviba, Karlis|Pan, Lydia|Rechkemmer, Gerhard
PMID: 12221251
Journal: Int J Oncol. 2002 Oct;21(4):895-900.
Title: Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer.
Author: Kirikoshi, Hiroyuki|Katoh, Masaru
PMID: 12239632
Journal: Toxicol Appl Pharmacol. 2002 Sep 15;183(3):160-7.
Title: Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation.
Author: Patten Hitt, Emma|DeLong, Mary J|Merrill, Alfred H Jr
PMID: 12383707
Journal: FEBS Lett. 2002 Nov 6;531(2):141-51.
Title: Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells.
Author: Bu, Shizhong|Blaukat, Andree|Fu, Xin|Heldin, Nils Erik|Landstrom, Marene
PMID: 12417302
Journal: J Asian Nat Prod Res. 2002 Dec;4(4):271-80.
Title: Inhibition of tumor growth by S-3-1, a synthetic intermediate of salvianolic acid A.
Author: Li, Hong-Yan|Li, Yan|Yan, Chun-Hong|Li, Lian-Niang|Chen, Xiao-Guang
PMID: 12450255
Journal: FASEB J. 2003 Jul;17(10):1316-8. Epub 2003 May 20.
Title: Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers.
Author: Grosch, Sabine|Tegeder, Irmgard|Schilling, Karin|Maier, Thorsten J|Niederberger, Ellen|Geisslinger, Gerd
PMID: 12759338
Journal: Carcinogenesis. 2003 Aug;24(8):1369-78.
Title: Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.
Author: Chen, Chi|Shen, Guoxiang|Hebbar, Vidya|Hu, Rong|Owuor, Edward D|Kong, A-N Tony
PMID: 12819184
Journal: Carcinogenesis. 2003 Aug;24(8):1361-7.
Title: The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
Author: Hu, Rong|Kim, Bok Ryang|Chen, Chi|Hebbar, Vidya|Kong, A-N Tony
PMID: 12819185
Journal: Cancer Sci. 2003 Mar;94(3):286-91.
Title: Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression.
Author: Satou, Mamoru|Aizawa, Syu|Hayakari, Makoto|Ookawa, Keizou|Tsuchida, Shigeki
PMID: 12824923
Journal: J Biol Chem. 2003 Dec 12;278(50):50442-8.
Title: Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling.
Author: Matos, Paulo|Collard, John G|Jordan, Peter
PMID: 14506233
Journal: Life Sci. 2003 Oct 17;73(22):2817-29.
Title: MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2.
Author: Jikuhara, Atsushi|Yoshii, Masanori|Iwagaki, Hiromi|Mori, Shuji|Nishibori, Masahiro|Tanaka, Noriaki
PMID: 14511767
Journal: Cancer Sci. 2003 Oct;94(10):886-93.
Title: Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine.
Author: Aizawa, Shu|Ookawa, Keizou|Kudo, Toshihiro|Asano, Junpei|Hayakari, Makoto|Tsuchida, Shigeki
PMID: 14556662
Journal: Cancer Res. 2003 Oct 15;63(20):6825-37.
Title: Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
Author: Xiao, Danhua|Pinto, John T|Soh, Jae-Won|Deguchi, Atsuko|Gundersen, Gregg G|Palazzo, Alexander F|Yoon, Jung-Taek|Shirin, Haim|Weinstein, I Bernard
PMID: 14583480
Journal: J Nutr. 2003 Nov;133(11 Suppl 1):3800S-3804S.
Title: The chemopreventive bioflavonoid apigenin modulates signal transduction pathways in keratinocyte and colon carcinoma cell lines.
Author: Van Dross, Rukiyah|Xue, Yue|Knudson, Alexandra|Pelling, Jill C
PMID: 14608117
Journal: Mol Pharmacol. 2004 Jan;65(1):235-43.
Title: Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines.
Author: Vasilevskaya, Irina A|Rakitina, Tatiana V|O'Dwyer, Peter J
PMID: 14722256
Journal: Cancer Biol Ther. 2004 Mar;3(3):296-301. Epub 2004 Mar 16.
Title: Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Author: Zhang, Lidong|Zhu, Hongbo|Davis, John J|Jacob, Dietmar|Wu, Shuhong|Teraishi, Fuminori|Gutierrez, Angelica|Wang, Yibin|Fang, Bingliang
PMID: 14749540
Journal: Pharm Res. 2004 Apr;21(4):649-60.
Title: Modulation of AP-1 by natural chemopreventive compounds in human colon HT-29 cancer cell line.
Author: Jeong, Woo-Sik|Kim, In-Wha|Hu, Rong|Kong, Ah-Ng Tony
PMID: 15139522
Journal: Pharmacol Res. 2004 Aug;50(2):201-7.
Title: Echinomycin and a novel analogue induce apoptosis of HT-29 cells via the activation of MAP kinases pathway.
Author: Park, Ju Youn|Park, Su Jung|Shim, Kwang Yong|Lee, Kyu Jae|Kim, Yun-Bong|Kim, Yong Hae|Kim, Soo Kie
PMID: 15177310
Journal: Drug Metab Dispos. 2004 Jul;32(7):685-8.
Title: C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Author: Yasunami, Yoko|Hara, Hirokazu|Iwamura, Tatsunori|Kataoka, Tadashi|Adachi, Tetsuo
PMID: 15205382
Journal: Carcinogenesis. 2004 Nov;25(11):2183-9. Epub 2004 Jul 15.
Title: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick Charles
PMID: 15256484
Journal: J Am Coll Surg. 2004 Aug;199(2):234-42.
Title: Critical involvement of stress-activated mitogen-activated protein kinases in the regulation of intracellular adhesion molecule-1 in serosal fibroblasts isolated from patients with Crohn's disease.
Author: Beddy, David J|Watson, William R|Fitzpatrick, John M|O'Connell, P Ronan
PMID: 15275879
Journal: Cancer Res. 2004 Aug 1;64(15):5162-71.
Title: Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-g
Author: Grau, Raquel|Iniguez, Miguel A|Fresno, Manuel
PMID: 15289320
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:143-50.
Title: Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.
Author: Tominaga, K|Higuchi, K|Sasaki, E|Suto, R|Watanabe, T|Fujiwara, Y|Oshitani, N|Matsumoto, T|Kim, S|Iwao, H|Arakawa, T
PMID: 15298620
Journal: J Cell Sci. 2004 Sep 15;117(Pt 20):4691-703.
Title: Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding.
Author: De Wever, Olivier|Westbroek, Wendy|Verloes, An|Bloemen, Nele|Bracke, Marc|Gespach, Christian|Bruyneel, Erik|Mareel, Marc
PMID: 15331629
Journal: Oncogene. 2004 Oct 7;23(46):7712-21.
Title: Luteolin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells.
Author: Shi, Ran-Xin|Ong, Choon-Nam|Shen, Han-Ming
PMID: 15334063
Journal: Postepy Hig Med Dosw (Online). 2004;58:428-37.
Title: [Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines].
Author: Pajak, Beata|Orzechowski, Arkadiusz
PMID: 15577750
Journal: Oncogene. 2005 Feb 3;24(6):1098-103.
Title: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
Author: Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto
PMID: 15592505
Journal: J Biol Chem. 2005 Mar 4;280(9):7634-44. Epub 2004 Dec 17.
Title: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
Author: Wang, Ling-Chi|Okitsu, Cindy Yen|Zandi, Ebrahim
PMID: 15611081
Journal: Cell Cycle. 2005 Mar;4(3):456-64.
Title: Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells.
Author: Caron, Ruben W|Yacoub, Adly|Mitchell, Clint|Zhu, Xiaoyu|Hong, Young|Sasazuki, Takehiko|Shirasawa, Senji|Hagan, Michael P|Grant, Steven|Dent, Paul
PMID: 15655348
Journal: Cell Physiol Biochem. 2005;15(1-4):29-40.
Title: TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
Author: Ahn, Dae-ho|Crawley, Suzanne C|Hokari, Ryota|Kato, Shingo|Yang, Stacey C|Li, Jian-Dong|Kim, Young S
PMID: 15665513
Journal: Biochem Pharmacol. 2005 Mar 1;69(5):831-9.
Title: Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53.
Author: Grosch, Sabine|Schilling, Karin|Janssen, Astrid|Maier, Thorsten J|Niederberger, Ellen|Geisslinger, Gerd
PMID: 15710360
Journal: Oncogene. 2005 Apr 14;24(16):2647-53.
Title: Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells.
Author: Fan, Fan|Wey, Jane S|McCarty, Marya F|Belcheva, Anna|Liu, Wenbiao|Bauer, Todd W|Somcio, Ray J|Wu, Yan|Hooper, Andrea|Hicklin, Daniel J|Ellis, Lee M
PMID: 15735759
Journal: Am J Pathol. 2005 Mar;166(3):751-60.
Title: Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages.
Author: Kuniyasu, Hiroki|Yano, Seiji|Sasaki, Takamitsu|Sasahira, Tomonori|Sone, Sabro|Ohmori, Hitoshi
PMID: 15743787
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: Dig Dis Sci. 2005 Mar;50(3):490-8.
Title: Butyrate-induced differentiation of colon cancer cells is PKC and JNK dependent.
Author: Orchel, Arkadiusz|Dzierzewicz, Zofia|Parfiniewicz, Beata|Weglarz, Ludmila|Wilczok, Tadeusz
PMID: 15810631
Journal: Cancer Lett. 2005 May 10;222(1):1-10.
Title: Wnt signaling in lung cancer.
Author: Mazieres, Julien|He, Biao|You, Liang|Xu, Zhidong|Jablons, David M
PMID: 15837535
Journal: Clin Cancer Res. 2005 Apr 15;11(8):3075-83.
Title: Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations.
Author: Meurette, Olivier|Lefeuvre-Orfila, Luz|Rebillard, Amelie|Lagadic-Gossmann, Dominique|Dimanche-Boitrel, Marie-Therese
PMID: 15837763
Journal: Carcinogenesis. 2005 Sep;26(9):1553-62. Epub 2005 Apr 28.
Title: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
Author: Kim, Mihye|Murakami, Akira|Kawabata, Kyuichi|Ohigashi, Hajime
PMID: 15860507
Journal: Lancet Oncol. 2005 May;6(5):322-7.
Title: The MAPK signalling pathways and colorectal cancer.
Author: Fang, Jing Yuan|Richardson, Bruce C
PMID: 15863380
Journal: World J Gastroenterol. 2005 May 28;11(20):3040-5.
Title: Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells.
Author: Yang, Kuo-Ching|Uen, Yih-Huei|Suk, Fat-Moon|Liang, Yu-Chih|Wang, Ying-Jan|Ho, Yuan-Soon|Li, I-Hsuan|Lin, Shyr-Yi
PMID: 15918186
Journal: Mol Cancer Ther. 2005 Jun;4(6):901-9.
Title: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.
Author: Li, Yin|Mao, Yuehua|Brandt-Rauf, Paul W|Williams, Ann C|Fine, Robert L
PMID: 15956247
Journal: Cancer Res. 2005 Jul 15;65(14):6380-7.
Title: Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Author: Teraishi, Fuminori|Wu, Shuhong|Zhang, Lidong|Guo, Wei|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16024641
Journal: Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16082182
Journal: Exp Cell Res. 2005 Oct 15;310(1):117-30.
Title: CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation.
Author: Brand, Stephan|Dambacher, Julia|Beigel, Florian|Olszak, Torsten|Diebold, Joachim|Otte, Jan-Michel|Goke, Burkhard|Eichhorst, Soren T
PMID: 16125170
Journal: Cell Mol Life Sci. 2005 Oct;62(19-20):2382-9.
Title: JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Author: Teraishi, F|Wu, S|Sasaki, J|Zhang, L|Davis, J J|Guo, W|Dong, F|Fang, B
PMID: 16179969
Journal: Biofactors. 2005;24(1-4):237-46.
Title: 4-hydroxynonenal and TGF-beta1 concur in inducing antiproliferative effects on the CaCo-2 human colon adenocarcinoma cell line.
Author: Vizio, Barbara|Poli, Giuseppe|Chiarpotto, Elena|Biasi, Fiorella
PMID: 16403984
Journal: J Pharmacol Exp Ther. 2006 Jan;316(1):25-34. Epub 2005 Sep 16.
Title: Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation.
Author: Hundley, Thomas R|Rigas, Basil
PMID: 16169935
Journal: Cancer Chemother Pharmacol. 2006 Feb;57(3):317-27. Epub 2005 Sep 17.
Title: p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.
Author: Shen, Guoxiang|Xu, Changjiang|Chen, Chi|Hebbar, Vidya|Kong, Ah-Ng Tony
PMID: 16170570
Journal: J Cell Biochem. 2006 Mar 1;97(4):709-23.
Title: Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.
Author: Brand, Stephan|Olszak, Torsten|Beigel, Florian|Diebold, Joachim|Otte, Jan-Michel|Eichhorst, Soeren T|Goke, Burkhard|Dambacher, Julia
PMID: 16215992
Journal: Cancer Lett. 2006 Sep 28;241(2):268-74.
Title: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers.
Author: Xia, Harry Hua-Xiang|He, Hua|De Wang, Ji|Gu, Qing|Lin, Marie C M|Zou, Bing|Yu, Li Fen|Sun, Yun Wei|Chan, Annie O O|Kung, Hsiang Fu|Wong, Benjamin Chun-Yu
PMID: 16337741
Journal: Int J Cancer. 2006 Jun 1;118(11):2758-64.
Title: TAK1-mediated stress signaling pathways are essential for TNF-alpha-promoted pulmonary metastasis of murine colon cancer cells.
Author: Choo, Min-Kyung|Sakurai, Hiroaki|Koizumi, Keiichi|Saiki, Ikuo
PMID: 16385569
Journal: Mol Cell Endocrinol. 2006 Mar 9;247(1-2):140-9. Epub 2006 Jan 27.
Title: Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
Author: Beales, Ian L P|Ogunwobi, O
PMID: 16442704
Journal: Mol Cell Biol. 2006 Feb;26(4):1297-306.
Title: Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion.
Author: Yang, Hsin-Sheng|Matthews, Connie P|Clair, Timothy|Wang, Qing|Baker, Alyson R|Li, Chou-Chi H|Tan, Tse-Hua|Colburn, Nancy H
PMID: 16449643
Journal: Anticancer Res. 2006 Jan-Feb;26(1A):121-7.
Title: Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells.
Author: Ahn, Eun Hyun|Schroeder, Joseph J
PMID: 16475687
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Carcinogenesis. 2006 Aug;27(8):1636-44.
Title: Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.
Author: Moussavi, Maryam|Assi, Kiran|Gomez-Munoz, Antonio|Salh, Baljinder
PMID: 16501251
Journal: Histol Histopathol. 2006 Jun;21(6):645-62.
Title: Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis.
Author: Matsuzaki, K
PMID: 16528675
Journal: Mol Cancer Ther. 2006 Mar;5(3):746-54.
Title: Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Author: Rice, Pamela L|Peters, Stevany L|Beard, K Scott|Ahnen, Dennis J
PMID: 16546990
Journal: Oncogene. 2006 Nov 9;25(53):7070-7. Epub 2006 May 22.
Title: Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis.
Author: Deng, R|Li, W|Guan, Z|Zhou, J-M|Wang, Y|Mei, Y-P|Li, M-T|Feng, G-K|Huang, W|Liu, Z-C|Han, Y|Zeng, Y-X|Zhu, X-F
PMID: 16715131
Journal: Free Radic Biol Med. 2006 Aug 1;41(3):443-54.
Title: c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa.
Author: Biasi, Fiorella|Vizio, Barbara|Mascia, Cinzia|Gaia, Ezio|Zarkovic, Neven|Chiarpotto, Elena|Leonarduzzi, Gabriella|Poli, Giuseppe
PMID: 16843825
Journal: Clin Cancer Res. 2006 Nov 1;12(21):6532-9.
Title: 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation.
Author: Zou, HuiChao|Adachi, Masaaki|Imai, Kohzoh|Hareyama, Masato|Yoshioka, Katsuji|Zhao, Shiguang|Shinomura, Yasuhisa
PMID: 17085668
Journal: Inflammopharmacology. 2006 Dec;14(5-6):198-203.
Title: TGF-beta during human colorectal carcinogenesis: the shift from epithelial to mesenchymal signaling.
Author: Matsuzaki, K|Seki, T|Okazaki, K
PMID: 17093904
Journal: Curr Cancer Drug Targets. 2006 Dec;6(8):681-9.
Title: Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids.
Author: Kim, Nam Deuk|Im, Eunok|Yoo, Young Hyun|Choi, Yung Hyun
PMID: 17168673
Journal: Int J Colorectal Dis. 2007 Apr;22(4):401-9. Epub 2006 Aug 16.
Title: The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt.
Author: Ogunwobi, Olorunseun O|Beales, Ian L P
PMID: 16912864
Journal: Biochem Pharmacol. 2007 Jan 1;73(1):68-76. Epub 2006 Sep 19.
Title: Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.
Author: Woo, Kyung Jin|Lee, Tae Jin|Lee, Sang Han|Lee, Jin-Man|Seo, Ji-Hyung|Jeong, Yong-Jin|Park, Jong-Wook|Kwon, Taeg Kyu
PMID: 17049495
Journal: Apoptosis. 2007 Feb;12(2):423-31.
Title: Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
Author: Lim, Soo-Jeong|Lee, Young-Ju|Park, Dae-Hun|Lee, Eunmyong|Choi, Moon-Kyung|Park, Wanseo|Chun, Kyung-Hee|Choi, Han-Gon|Cho, Jung Sik
PMID: 17191116
Journal: J Cell Biochem. 2007 Aug 1;101(5):1165-75.
Title: NF-kappaB pathway is involved in griseofulvin-induced G2/M arrest and apoptosis in HL-60 cells.
Author: Uen, Yih-Huei|Liu, Der-Zen|Weng, Meng-Shih|Ho, Yuan-Soon|Lin, Shyr-Yi
PMID: 17226769
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: Eur J Pharmacol. 2007 Apr 10;560(2-3):95-100. Epub 2007 Jan 19.
Title: JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo.
Author: Song, Zibo|Tong, Chang|Liang, Jiao|Dockendorff, Ashley|Huang, Chuanshu|Augenlicht, Leonard H|Yang, Wancai
PMID: 17292881
Journal: Mol Pharmacol. 2007 May;71(5):1381-8. Epub 2007 Feb 12.
Title: A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells.
Author: Ju, Wei|Wang, Xia|Shi, Honglian|Chen, Wenshu|Belinsky, Steven A|Lin, Yong
PMID: 17296806
Journal: Int J Cancer. 2007 Jul 15;121(2):431-41.
Title: TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response.
Author: Nowis, Dominika|McConnell, Elizabeth J|Dierlam, Lindsey|Palamarchuk, Alla|Lass, Agnieszka|Wojcik, Cezary
PMID: 17373661
Journal: Int J Oncol. 2007 May;30(5):1273-7.
Title: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17390031
Journal: Anticancer Res. 2007 Mar-Apr;27(2):741-8.
Title: Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase.
Author: Lea, Michael A|Ibeh, Chinwe|Shah, Neel|Moyer, Mary P
PMID: 17465197
Journal: Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28.
Title: Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Author: Grijelmo, Clara|Rodrigue, Christelle|Svrcek, Magalie|Bruyneel, Erik|Hendrix, An|de Wever, Olivier|Gespach, Christian
PMID: 17478078
Journal: Cancer Res. 2007 May 15;67(10):4700-8.
Title: Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells.
Author: Wang, Lin|Zhang, Yujing|Li, Haiyang|Xu, Zhiheng|Santella, Regina M|Weinstein, I Bernard
PMID: 17510397
Journal: J Biol Chem. 2007 Aug 3;282(31):22298-306.
Title: Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
Author: Fu, Ping|Thompson, Julian A|Bach, Leon A
PMID: 17519236
Journal: Am J Pathol. 2007 Jul;171(1):297-303.
Title: c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression.
Author: Tong, Chang|Yin, Zhinan|Song, Zibo|Dockendorff, Ashley|Huang, Chuanshu|Mariadason, John|Flavell, Richard A|Davis, Roger J|Augenlicht, Leonard H|Yang, Wancai
PMID: 17591974
Journal: Cancer Lett. 2007 Oct 28;256(2):207-17. Epub 2007 Jul 20.
Title: Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.
Author: Deng, Haiyun|Ravikumar, T S|Yang, Weng-Lang
PMID: 17640799
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G758-72. Epub 2007 Jul
Title: Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells.
Author: Garneau, Hugo|Alvarez, Laetitia|Paquin, Marie-Christine|Lussier, Carine|Rancourt, Claudine|Tremblay, Eric|Beaulieu, Jean-Francois|Rivard, Nathalie
PMID: 17656449
Journal: Int J Mol Med. 2007 Sep;20(3):405-9.
Title: Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17671748
Journal: Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author: Hsu, Wen-Hsiu|Hsieh, Yih-Shou|Kuo, Hsing-Chun|Teng, Chun-Yuh|Huang, Hai-I|Wang, Chau-Jong|Yang, Shun-Fa|Liou, Yi-Sheng|Kuo, Wu-Hsien
PMID: 17673978
Journal: Cancer Res. 2007 Aug 15;67(16):7773-81.
Title: Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition.
Author: Wang, Qingding|Zhou, Yuning|Wang, Xiaofu|Chung, Dai H|Evers, B Mark
PMID: 17699782
Journal: Regul Pept. 2007 Dec 4;144(1-3):34-42. Epub 2007 Jun 7.
Title: The CCK-2/gastrin splice variant receptor retaining intron 4 transactivates the COX-2 promoter in vitro.
Author: Huang, He|Ansorge, Nikolaus|Schrader, Henning|Banasch, Matthias|Yu, Hong-Gang|Schmidt, Wolfgang E|Hocker, Michael|Schmitz, Frank
PMID: 17936921
Journal: Beijing Da Xue Xue Bao. 2007 Oct 18;39(5):453-7.
Title: [Regulation of promatrilysin expression by tissue factor/actived coagulation factor VII complex in LoVo colon cancer cell line].
Author: Tang, Jian-qiang|Wan, Yuan-lian|Liu, Yu-cun|Rong, Long|Wang, Xin|Wu, Tao|Pan, Yi-sheng|Zhu, Jing
PMID: 17940558
Journal: Int J Oncol. 2007 Dec;31(6):1501-8.
Title: Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion.
Author: Van Slambrouck, Severine|Grijelmo, Clara|De Wever, Olivier|Bruyneel, Erik|Emami, Shahin|Gespach, Christian|Steelant, Wim F A
PMID: 17982677
Journal: Pharm Res. 2008 Feb;25(2):387-99. Epub 2007 Jul 27.
Title: Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Author: Nair, Sujit|Hebbar, Vidya|Shen, Guoxiang|Gopalakrishnan, Avantika|Khor, Tin Oo|Yu, Siwang|Xu, Changjiang|Kong, Ah-Ng
PMID: 17657594
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G599-609.
Title: Saccharomyces boulardii interferes with Shigella pathogenesis by postinvasion signaling events.
Author: Mumy, Karen L|Chen, Xinhua|Kelly, Ciaran P|McCormick, Beth A
PMID: 18032477
Journal: Toxicol Appl Pharmacol. 2008 Feb 15;227(1):136-46.
Title: Polymeric black tea polyphenols inhibit 1,2-dimethylhydrazine induced colorectal carcinogenesis by inhibiting cell proliferation via Wnt/beta-catenin pathway.
Author: Patel, Rachana|Ingle, Arvind|Maru, Girish B
PMID: 18037152
Journal: Anticancer Drugs. 2008 Jan;19(1):55-64.
Title: Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells.
Author: Chen, Yu-Jen|Kuo, Cheng-Deng|Tsai, Yin-Meng|Yu, Chih-Chia|Wang, Guang-Sheng|Liao, Hui-Fen
PMID: 18043130
Journal: Gastroenterology. 2008 Jan;134(1):281-91.
Title: Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells.
Author: Yang, Heping|Ara, Ainhoa Iglesias|Magilnick, Nathaniel|Xia, Meng|Ramani, Komal|Chen, Hui|Lee, Taunia D|Mato, Jose M|Lu, Shelly C
PMID: 18045590
Journal: Br J Pharmacol. 2008 Mar;153(5):870-8. Epub 2007 Dec 17.
Title: Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29).
Author: Gallicchio, M|Rosa, A C|Dianzani, C|Brucato, L|Benetti, E|Collino, M|Fantozzi, R
PMID: 18084318
Journal: J Biol Chem. 2008 Feb 29;283(9):5533-41.
Title: A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells.
Author: Rouget, Raphael|Auclair, Yannick|Loignon, Martin|Affar, El Bachir|Drobetsky, Elliot A
PMID: 18093981
Journal: Mol Carcinog. 2008 Jul;47(7):519-25.
Title: Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.
Author: Soh, Jae-Won|Kazi, Julhash U|Li, Han|Thompson, W Joseph|Weinstein, I Bernard
PMID: 18163459
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Biol Pharm Bull. 2008 Jan;31(1):79-84.
Title: Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells.
Author: Inaba, Hiroyuki|Nagaoka, Yasuo|Kushima, Yukihiro|Kumagai, Ayako|Matsumoto, Yoshinori|Sakaguchi, Minoru|Baba, Kimiye|Uesato, Shinichi
PMID: 18175946
Journal: Mol Pharmacol. 2008 Jul;74(1):246-54.
Title: Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin.
Author: Vasilevskaya, Irina A|Selvakumaran, Muthu|O'Dwyer, Peter J
PMID: 18436711
Journal: Biol Pharm Bull. 2008 May;31(5):916-20.
Title: Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism.
Author: Yamakawa, Satoshi|Demizu, Aya|Kawaratani, Yasuyuki|Nagaoka, Yasuo|Terada, Yuji|Maruyama, Sakiko|Uesato, Shinichi
PMID: 18451518
Journal: Carcinogenesis. 2008 Jun;29(6):1139-47.
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
Author: Lei, Ping|Abdelrahim, Maen|Cho, Sung Dae|Liu, Shengxi|Chintharlapalli, Sudhakar|Safe, Stephen
PMID: 18460448
Journal: Int J Oncol. 2008 Jun;32(6):1221-6.
Title: Involvement of Smad3 phosphoisoform-mediated signaling in the development of colonic cancer in IL-10-deficient mice.
Author: Hachimine, Daisaku|Uchida, Kazushige|Asada, Masanori|Nishio, Akiyoshi|Kawamata, Seiji|Sekimoto, Go|Murata, Miki|Yamagata, Hideo|Yoshida, Katsunori|Mori, Shigeo|Tahashi, Yoshiya|Matsuzaki, Koichi|Okazaki, Kazuichi
PMID: 18497983
Journal: Biol Pharm Bull. 2008 Jun;31(6):1177-81.
Title: Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
Author: Nagaoka, Yasuo|Otsuki, Kota|Fujita, Tetsuro|Uesato, Shinichi
PMID: 18520051
Journal: Cancer Gene Ther. 2008 Sep;15(9):616-24.
Title: JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.
Author: Hu, W|Hofstetter, W|Guo, W|Li, H|Pataer, A|Peng, H H|Guo, Z S|Bartlett, D L|Lin, A|Swisher, S G|Fang, B
PMID: 18535619
Journal: Clin Cancer Res. 2008 Jul 1;14(13):4250-8.
Title: Moscatilin induces apoptosis in human colorectal cancer cells: a crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage.
Author: Chen, Tzu-Hsuan|Pan, Shiow-Lin|Guh, Jih-Hwa|Liao, Cho-Hwa|Huang, Der-Yi|Chen, Chien-Chih|Teng, Che-Ming
PMID: 18594007
Journal: Gut. 2008 Nov;57(11):1509-17.
Title: Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.
Author: Binion, D G|Otterson, M F|Rafiee, P
PMID: 18596194
Journal: Bioorg Med Chem. 2008 Oct 1;16(19):9065-78.
Title: Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties.
Author: Ortin, Irene|Gonzalez, Juan Francisco|Cuesta, Elena de la|Manguan-Garcia, Cristina|Perona, Rosario|Avendano, Carmen
PMID: 18799316
Journal: Free Radic Biol Med. 2008 Dec 15;45(12):1642-52.
Title: Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.
Author: Kuwano, Yuki|Tominaga, Kumiko|Kawahara, Tsukasa|Sasaki, Hidekazu|Takeo, Keiko|Nishida, Kensei|Masuda, Kiyoshi|Kawai, Tomoko|Teshima-Kondo, Shigetada|Rokutan, Kazuhito
PMID: 18929641
Journal: PLoS One. 2008;3(12):e4054.
Title: Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin.
Author: Gavin, Elaine J|Song, Bo|Wang, Yuan|Xi, Yaguang|Ju, Jingfang
PMID: 19112505
Journal: Chem Biol Interact. 2009 Feb 12;177(3):218-26.
Title: Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain.
Author: Ahmed, Kanwal|Matsuya, Yuji|Nemoto, Hideo|Zaidi, Syed Faisal Haider|Sugiyama, Toshiro|Yoshihisa, Yoko|Shimizu, Tadamichi|Kondo, Takashi
PMID: 19014919
Journal: Food Chem Toxicol. 2009 Jan;47(1):171-9.
Title: Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways.
Author: Yang, Jai-Sing|Chen, Guang-Wei|Hsia, Te-Chun|Ho, Heng-Chien|Ho, Chin-Chin|Lin, Meng-Wei|Lin, Song-Shei|Yeh, Ru-Duan|Ip, Siu-Wan|Lu, Hsu-Fung|Chung, Jing-Gung
PMID: 19038304
Journal: Int J Cancer. 2009 Mar 15;124(6):1322-9.
Title: N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1.
Author: Laezza, Chiara|Caruso, Maria Gabriella|Gentile, Teresa|Notarnicola, Maria|Malfitano, Anna Maria|Di Matola, Tiziana|Messa, Caterina|Gazzerro, Patrizia|Bifulco, Maurizio
PMID: 19058178
Journal: Cancer Lett. 2009 May 8;277(1):108-13.
Title: p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047.
Author: Adachi, Seiji|Natsume, Hideo|Yamauchi, Junichi|Matsushima-Nishiwaki, Rie|Joe, Andrew K|Moriwaki, Hisataka|Kozawa, Osamu
PMID: 19138820
Journal: Cancer Lett. 2009 Jun 28;279(1):93-100.
Title: Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts.
Author: An, Min Ji|Cheon, Jae Hee|Kim, Seung Won|Kim, Eun Soo|Kim, Tae Il|Kim, Won Ho
PMID: 19232820
Journal: Biochem Biophys Res Commun. 2009 May 1;382(2):451-6.
Title: Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells.
Author: Wu, Ya Chun|Wu, William Ka Kei|Li, Youming|Yu, Le|Li, Zhi Jie|Wong, Clover Ching Man|Li, Hai Tao|Sung, Joseph Jao Yiu|Cho, Chi Hin
PMID: 19289106
Journal: Lab Invest. 2009 Jun;89(6):717-25.
Title: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author: Xiong, Hua|Su, Wen-Yu|Liang, Qin-Chuan|Zhang, Zhi-Gang|Chen, Hui-Min|Du, Wan|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19290007
Journal: Mol Cell Biochem. 2009 Aug;328(1-2):201-8.
Title: MAP kinases in proliferating human colon cancer Caco-2 cells.
Author: Buzzi, Natalia|Colicheo, Andrea|Boland, Ricardo|de Boland, Ana Russo
PMID: 19301097
Journal: Br J Cancer. 2009 May 5;100(9):1415-24.
Title: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.
Author: Mahalingam, D|Keane, M|Pirianov, G|Mehmet, H|Samali, A|Szegezdi, E
PMID: 19352384
Journal: J Pathol. 2009 Aug;218(4):514-9.
Title: Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer.
Author: Gulmann, Christian|Sheehan, Katherine M|Conroy, Ronan M|Wulfkuhle, Julia D|Espina, Virginia|Mullarkey, Michelle J|Kay, Elaine W|Liotta, Lance A|Petricoin, Emanuel F 3rd
PMID: 19396842
Journal: Cancer Lett. 2009 Sep 28;283(1):108-17.
Title: Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells.
Author: Palozza, Paola|Torelli, Cristiana|Boninsegna, Alma|Simone, Rossella|Catalano, Assunta|Mele, Maria Cristina|Picci, Nevio
PMID: 19423215
Journal: Acta Biochim Biophys Sin (Shanghai). 2009 Jun;41(6):504-14.
Title: NGX6 inhibits AP-1 and Ets-1 expression and down-regulates cyclin D1 in human colorectal cancer.
Author: Peng, Ya|Li, Hongtao|Wu, Minghua|Wang, Xiaoyan|Fan, Songqing|Liu, Fen|Xiang, Bo|Guo, Qin|Tang, Xueyuan|Shen, Shourong
PMID: 19499154
Journal: Cancer Res. 2009 Jul 1;69(13):5321-30.
Title: Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
Author: Matsuzaki, Koichi|Kitano, Chiaki|Murata, Miki|Sekimoto, Go|Yoshida, Katsunori|Uemura, Yoshiko|Seki, Toshihito|Taketani, Shigeru|Fujisawa, Jun-ichi|Okazaki, Kazuichi
PMID: 19531654
Journal: Food Chem Toxicol. 2009 Sep;47(9):2366-73.
Title: Activation of several concurrent proapoptic pathways by sulforaphane in human colon cancer cells SW620.
Author: Rudolf, E|Andelova, H|Cervinka, M
PMID: 19563859
Journal: Pathobiology. 2009;76(4):155-62.
Title: Suppression of dendritic cells by HMGB1 is associated with lymph node metastasis of human colon cancer.
Author: Kusume, Akiko|Sasahira, Tomonori|Luo, Yi|Isobe, Mamoru|Nakagawa, Naoya|Tatsumoto, Naokuni|Fujii, Kiyomu|Ohmori, Hitoshi|Kuniyasu, Hiroki
PMID: 19571604
Journal: Clin Cancer Res. 2009 Sep 1;15(17):5414-25.
Title: 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Author: Shin, Sung-Won|Seo, Chi-Yeon|Han, Hoon|Han, Jin-Yeong|Jeong, Jin-Sook|Kwak, Jong-Young|Park, Joo-In
PMID: 19690198
Journal: J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74.
Title: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.
Author: Shan, Jian-zhen|Xuan, Yan-yan|Zheng, Shu|Dong, Qi|Zhang, Su-zhan
PMID: 19735099
Journal: Br J Cancer. 2009 Oct 20;101(8):1374-81.
Title: Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells.
Author: Ueno, K|Hazama, S|Mitomori, S|Nishioka, M|Suehiro, Y|Hirata, H|Oka, M|Imai, K|Dahiya, R|Hinoda, Y
PMID: 19773752
Journal: Cancer Res Treat. 2009 Sep;41(3):164-70.
Title: TNF-alpha downregulates E-cadherin and sensitizes response to gamma-irradiation in Caco-2 cells.
Author: Yi, Jae Youn|Jung, Yu-Jin|Choi, Sun Shim|Chung, Eunkyung
PMID: 19809566
Journal: Biochim Biophys Acta. 2009 Dec;1790(12):1651-9.
Title: Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line.
Author: Buzzi, Natalia|Bilbao, Paola Scodelaro|Boland, Ricardo|de Boland, Ana Russo
PMID: 19836435
Journal: Oncol Rep. 2009 Dec;22(6):1505-12.
Title: Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo.
Author: Lee, Se-Jung|Cho, Young-Hwa|Kim, Heejong|Park, Keerang|Park, Sung-Kyu|Ha, Sang-Do|Kim, Wun-Jae|Moon, Sung-Kwon
PMID: 19885606
Journal: J Cell Mol Med. 2010 Mar;14(3):710-25.
Title: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells.
Author: Dai, Shengming|Jiang, Lijun|Wang, Guisheng|Zhou, Xiangyang|Wei, Xiaomou|Cheng, Hongge|Wu, Zhen|Wei, Dong
PMID: 19243468
Journal: Antioxid Redox Signal. 2010 May 1;12(9):1101-9.
Title: Butyrate-stimulated H2S production in colon cancer cells.
Author: Cao, Qiuhui|Zhang, Li|Yang, Guangdong|Xu, Changqing|Wang, Rui
PMID: 19803745
Journal: Food Chem Toxicol. 2010 Jan;48(1):277-83.
Title: c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells.
Author: Lee, Se-Jung|Moon, Gi-Seong|Jung, Kyung-Hwan|Kim, Wun-Jae|Moon, Sung-Kwon
PMID: 19833164
Journal: Apoptosis. 2010 Feb;15(2):183-95.
Title: Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
Author: El-Najjar, Nahed|Chatila, Manal|Moukadem, Hiba|Vuorela, Heikki|Ocker, Matthias|Gandesiri, Muktheshwar|Schneider-Stock, Regine|Gali-Muhtasib, Hala
PMID: 19882352
Journal: Eur J Cancer Prev. 2010 Mar;19(2):153-9.
Title: The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells.
Author: Choi, Kyeong-Hee|Kim, Hyung-Kook|Kim, Jun-Hee|Choi, Eun-Sun|Shin, Ji-Ae|Lee, Syng-Ook|Chintharlapalli, Sudhakar|Safe, Stephen|Abdelrahim, Maen|Kong, Gu|Choi, Hong Seok|Jung, Ji-Youn|Cho, Hyun-Tae|Cho, Nam-Pyo|Cho, Sung-Dae
PMID: 19949342
Journal: Prostaglandins Leukot Essent Fatty Acids. 2010 Feb-Mar;82(2-3):131-9.
Title: Hypertonic environment elicits cyclooxygenase-2-driven prostaglandin E2 generation by colon cancer cells: role of cytosolic phospholipase A2-alpha and kinase signaling pathways.
Author: Gentile, Luciana B|Piva, Bruno|Capizzani, Bianca C|Furlaneto, Luiz G B|Moreira, Luciana S|Zamith-Miranda, Daniel|Diaz, Bruno L
PMID: 20004562
Journal: Int J Cancer. 2010 Sep 1;127(5):1220-9.
Title: Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1.
Author: Wang, Lei|Kuang, Lisha|Pan, Xinhua|Liu, Junchen|Wang, Qian|Du, Bing|Li, Dali|Luo, Jian|Liu, Mingyao|Hou, Aijun|Qian, Min
PMID: 20017136
Journal: Eur J Cancer. 2010 Mar;46(4):791-9.
Title: HMGB1 attenuates anti-metastatic defence of the liver in colorectal cancer.
Author: Luo, Yi|Ohmori, Hitoshi|Fujii, Kiyomu|Moriwaka, Yukiko|Sasahira, Tomonori|Kurihara, Miyako|Tatsumoto, Naokuni|Sasaki, Takamitsu|Yamashita, Yuichi|Kuniyasu, Hiroki
PMID: 20018503
Journal: Nutr Cancer. 2010;62(1):85-92.
Title: Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells.
Author: Zeng, Huawei|Botnen, James H|Briske-Anderson, Mary
PMID: 20043263
Journal: PLoS One. 2010 Jan 27;5(1):e8925.
Title: Interaction of Saccharomyces boulardii with Salmonella enterica serovar Typhimurium protects mice and modifies T84 cell response to the infection.
Author: Martins, Flaviano S|Dalmasso, Guillaume|Arantes, Rosa M E|Doye, Anne|Lemichez, Emmanuel|Lagadec, Patricia|Imbert, Veronique|Peyron, Jean-Francois|Rampal, Patrick|Nicoli, Jacques R|Czerucka, Dorota
PMID: 20111723
Journal: J Agric Food Chem. 2010 Mar 10;58(5):2935-42.
Title: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Author: Lai, Kuang-Chi|Huang, An-Cheng|Hsu, Shu-Chun|Kuo, Chao-Lin|Yang, Jai-Sing|Wu, Shin-Hwar|Chung, Jing-Gung
PMID: 20136087
Journal: Int J Mol Med. 2010 Apr;25(4):635-41.
Title: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.
Author: Kim, Wun-Jae|Lee, Se-Jung|Choi, Young Deuk|Moon, Sung-Kwon
PMID: 20198313
Journal: Int J Oncol. 2010 Apr;36(4):941-53.
Title: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
Author: Lee, Hwa Young|Crawley, Suzanne|Hokari, Ryota|Kwon, Sungwon|Kim, Young S
PMID: 20198339
Journal: J Biol Chem. 2010 May 7;285(19):14617-27.
Title: AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma.
Author: Kim, Min-Jung|Park, In-Ja|Yun, Hee|Kang, Insug|Choe, Wonchae|Kim, Sung-Soo|Ha, Joohun
PMID: 20220132
Journal: Mol Biol Rep. 2010 Dec;37(8):3801-12.
Title: Inhibition of TNFalpha-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-kappaB- and MAPK-dependent mechanisms.
Author: Ruimi, Nili|Petrova, Roumyana D|Agbaria, Riad|Sussan, Sherbel|Wasser, Solomon P|Reznick, Abraham Z|Mahajna, Jamal
PMID: 20224909
Journal: Chem Biol Interact. 2010 May 14;185(3):174-81.
Title: Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells.
Author: Zhang, Yu|Zhou, Liang|Bao, Yong Li|Wu, Yin|Yu, Chun Lei|Huang, Yan Xin|Sun, Ying|Zheng, Li Hua|Li, Yu Xin
PMID: 20346929
Journal: Oncogene. 2010 Jun 10;29(23):3423-34.
Title: PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.
Author: Kwon, I-K|Wang, R|Thangaraju, M|Shuang, H|Liu, K|Dashwood, R|Dulin, N|Ganapathy, V|Browning, D D
PMID: 20348951
Journal: Mol Cell Biochem. 2010 Sep;342(1-2):63-70.
Title: 17beta-estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells.
Author: Lai, Tung-Yuan|Chen, Li-Mien|Lin, Jing-Ying|Tzang, Bor-Show|Lin, James A|Tsai, Chang-Hai|Lin, Yueh-Min|Huang, Chih-Yang|Liu, Chung-Jung|Hsu, Hsi-Hsien
PMID: 20446020
Journal: J Cell Biochem. 2010 Jun 1;110(3):581-8.
Title: ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells.
Author: Yang, Min|Yu, Mingcan|Guan, Dongyin|Gu, Jinfa|Cao, Xin|Wang, Weiyun|Zheng, Shu|Xu, Yingying|Shen, Zonghou|Liu, Xinyuan
PMID: 20512919
Journal: J Cell Biochem. 2010 Aug 1;110(5):1073-81.
Title: Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors.
Author: Alcala, Marco A Jr|Park, Kyungsoo|Yoo, Jinsang|Lee, Dae-Hee|Park, Bae-Hang|Lee, Byeong-Chel|Bartlett, David L|Lee, Yong J
PMID: 20544795
Journal: Biochim Biophys Acta. 2010 Sep;1800(9):946-55.
Title: Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells.
Author: Buzzi, Natalia|Boland, Ricardo|Russo de Boland, Ana
PMID: 20562007
Journal: Phytother Res. 2010 Dec;24(12):1870-6.
Title: Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression.
Author: Lee, Se-Jung|Park, Keerang|Ha, Sang-Do|Kim, Wun-Jae|Moon, Sung-Kwon
PMID: 20564491
Journal: Oncogene. 2010 Sep 16;29(37):5182-92.
Title: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.
Author: Lee, S-H|Bahn, J H|Whitlock, N C|Baek, S J
PMID: 20581861
Journal: Mol Nutr Food Res. 2010 Dec;54(12):1807-18.
Title: Phytate hydrolysate induces circumferential F-actin ring formation at cell-cell contacts by a Rho-associated kinase-dependent mechanism in colorectal cancer HT-29 cells.
Author: Suzuki, Takuya|Hara, Hiroshi
PMID: 20626001
Journal: Apoptosis. 2010 Dec;15(12):1540-8.
Title: JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative.
Author: Kim, Dong-Myung|Won, Misun|Chung, Chung-Sook|Kim, Semi|Yim, Hyeon Joo|Jung, Sang-Hun|Jeong, ShinWu
PMID: 20683666
Journal: J Zhejiang Univ Sci B. 2010 Sep;11(9):654-60.
Title: Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules.
Author: He, Wei|Zhang, Mei-fang|Ye, Jun|Jiang, Ting-ting|Fang, Xu|Song, Ying
PMID: 20803769
Journal: J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author: Sung, Bokyung|Ravindran, Jayaraj|Prasad, Sahdeo|Pandey, Manoj K|Aggarwal, Bharat B
PMID: 20837473
Journal: Mol Cell Biochem. 2010 Dec;345(1-2):283-90.
Title: Differential miRNA expression and their target genes between NGX6-positive and negative colon cancer cells.
Author: Wang, Xiao-Yan|Wu, Ming-Hua|Liu, Fen|Li, Yu|Li, Nan|Li, Gui-Yuan|Shen, Shou-Rong
PMID: 20859756
Journal: J Agric Food Chem. 2010 Oct 27;58(20):11148-55.
Title: Phenethyl isothiocyanate inhibited tumor migration and invasion via suppressing multiple signal transduction pathways in human colon cancer HT29 cells.
Author: Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Ip, Siu-Wan|Yang, Jai-Sing|Hsu, Yuan-Man|Huang, Hui-Ying|Wu, Shin-Hwar|Chung, Jing-Gung
PMID: 20863062
Journal: Biomed Pharmacother. 2010 Nov;64(9):583-8.
Title: GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Author: Miao, Yufeng|Zhang, Youwei|Wan, Haijun|Chen, Longbang|Wang, Fangyu
PMID: 20888181
Journal: Cancers (Basel). 2010;3(1):285-97.
Title: Enteric bacteria and cancer stem cells.
Author: Sun, Jun
PMID: 21297903
Journal: Int J Mol Sci. 2010;11(12):4916-31.
Title: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells.
Author: Lee, In Kyung|Kang, Kyoung Ah|Lim, Chae Moon|Kim, Ki Cheon|Kim, Hee Sun|Kim, Dong Hyun|Kim, Bum Joon|Chang, Weon Young|Choi, Jae Hyuck|Hyun, Jin Won
PMID: 21614182
Journal: Food Chem Toxicol. 2011 Jan;49(1):149-54.
Title: Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells--involvement of ROS generation and polyamine depletion.
Author: Wang, Lan|Xu, Ming Lu|Hu, Jian He|Rasmussen, Soren K|Wang, Myeong-Hyeon
PMID: 20940027
Journal: J Biol Chem. 2011 Feb 18;286(7):5546-57.
Title: Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
Author: Prasad, Sahdeo|Yadav, Vivek R|Kannappan, Ramaswamy|Aggarwal, Bharat B
PMID: 21156789
Journal: Phytother Res. 2011 Jul;25(7):959-64.
Title: Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma.
Author: Son, Seung Hwa|Park, Kwang-Kyun|Park, Sun Kyu|Kim, Young Choong|Kim, Yeong Shik|Lee, Sang-Kook|Chung, Won-Yoon
PMID: 21170925
Journal: Nature. 2011 Jan 13;469(7329):231-5.
Title: c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex.
Author: Aguilera, Cristina|Nakagawa, Kentaro|Sancho, Rocio|Chakraborty, Atanu|Hendrich, Brian|Behrens, Axel
PMID: 21196933
Journal: Carcinogenesis. 2011 May;32(5):667-75.
Title: COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer.
Author: Sui, Hua|Zhou, Shoufeng|Wang, Yan|Liu, Xuan|Zhou, Lihong|Yin, Peihao|Fan, Zhongze|Li, Qi
PMID: 21296766
Journal: Gastroenterology. 2011 May;140(5):1556-63.e6.
Title: JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice.
Author: Fujishita, Teruaki|Aoki, Masahiro|Taketo, Makoto M
PMID: 21320501
Journal: J Surg Res. 2011 May 15;167(2):e193-8.
Title: Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
Author: Benoit, Michael|Dormond-Meuwly, Anne|Demartines, Nicolas|Dormond, Olivier
PMID: 21324487
Journal: J Dig Dis. 2011 Apr;12(2):110-6.
Title: RNA interference (RNAi) of Ufd1 protein can sensitize a hydroxycamptothecin-resistant colon cancer cell line SW1116/HCPT to hydroxycamptothecin.
Author: Chen, Xiang|Ran, Zhi Hua|Tong, Jin Lu|Nie, Fang|Zhu, Ming Ming|Xu, Xi Tao|Xiao, Shu Dong
PMID: 21401896
Journal: Pathol Int. 2011 Apr;61(4):210-20.
Title: Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression.
Author: Lee, Seok|Song, Young-A|Park, Young-Lan|Cho, Sung-Bum|Lee, Wan-Sik|Lee, Jae-Hyuk|Chung, Ik-Joo|Kim, Kyung-Keun|Rew, Jong-Sun|Joo, Young-Eun
PMID: 21418393
Journal: Korean J Physiol Pharmacol. 2011 Feb;15(1):1-7.
Title: Involvement of ROS in Curcumin-induced Autophagic Cell Death.
Author: Lee, Youn Ju|Kim, Nam-Yi|Suh, Young-Ah|Lee, Chuhee
PMID: 21461234
Journal: Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106.
Title: Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Author: Colin, Didier|Limagne, Emeric|Jeanningros, Sylvie|Jacquel, Arnaud|Lizard, Gerard|Athias, Anne|Gambert, Philippe|Hichami, Aziz|Latruffe, Norbert|Solary, Eric|Delmas, Dominique
PMID: 21467134
Journal: Oncol Rep. 2011 Jul;26(1):109-14.
Title: Lupulone triggers p38 MAPK-controlled activation of p53 and of the TRAIL receptor apoptotic pathway in human colon cancer-derived metastatic cells.
Author: Lamy, Virginie|Bousserouel, Souad|Gosse, Francine|Minker, Carole|Lobstein, Annelise|Raul, Francis
PMID: 21519792
Journal: BMC Cancer. 2011 Apr 27;11:154.
Title: The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism.
Author: Reyes-Zurita, Fernando J|Pachon-Pena, Gisela|Lizarraga, Daneida|Rufino-Palomares, Eva E|Cascante, Marta|Lupianez, Jose A
PMID: 21524306
Journal: Toxicol In Vitro. 2011 Oct;25(7):1302-9.
Title: Sulforaphane induces cytotoxicity and lysosome- and mitochondria-dependent cell death in colon cancer cells with deleted p53.
Author: Rudolf, Emil|Cervinka, Miroslav
PMID: 21557998
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Mar;33(3):178-82.
Title: [Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms].
Author: Liu, Shi-quan|Qin, Meng-bin|Huang, Jie-an|Zhong, Yue-yuan|Tang, Guo-du|Jiang, Hai-xing
PMID: 21575515
Journal: Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title: Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author: Dolloff, Nathan G|Mayes, Patrick A|Hart, Lori S|Dicker, David T|Humphreys, Robin|El-Deiry, Wafik S
PMID: 21653830
Journal: BMC Dev Biol. 2011 Jun 14;11:41.
Title: The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor.
Author: VanZomeren-Dohm, Adrienne|Sarro, Joseph|Flannery, Ellen|Duman-Scheel, Molly
PMID: 21672235
Journal: Gastroenterology. 2011 Aug;141(2):663-73.
Title: Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.
Author: El Fajoui, Zineb|Toscano, Florent|Jacquemin, Guillaume|Abello, Jacques|Scoazec, Jean-Yves|Micheau, Olivier|Saurin, Jean-Christophe
PMID: 21683075
Journal: Oncol Rep. 2011 Oct;26(4):971-8.
Title: Downregulation of discoidin domain receptor 2 in A375 human melanoma cells reduces its experimental liver metastasis ability.
Author: Badiola, Iker|Villace, Patricia|Basaldua, Iratxe|Olaso, Elvira
PMID: 21701781
Journal: Hum Cell. 2011 Sep;24(3):121-6.
Title: Enormous influence of TNIK knockdown on intracellular signals and cell survival.
Author: Gui, Jinghua|Yang, Baotian|Wu, Jinyun|Zhou, Xiumei
PMID: 21710359
Journal: Free Radic Biol Med. 2011 Oct 1;51(7):1365-75.
Title: Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
Author: Xie, Chuan-Ming|Chan, Wood Yee|Yu, Sidney|Zhao, Jun|Cheng, Christopher H K
PMID: 21763418
Journal: Int J Biol Sci. 2011;7(6):869-80. Epub 2011 Jul 19.
Title: Dimerumic acid inhibits SW620 cell invasion by attenuating H(2)O(2)-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner.
Author: Ho, Bing-Ying|Wu, Yao-Ming|Chang, King-Jen|Pan, Tzu-Ming
PMID: 21814482
Journal: Curr Cancer Drug Targets. 2011 Oct;11(8):976-86.
Title: RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors.
Author: Martin, S E|Wu, Z-H|Gehlhaus, K|Jones, T L|Zhang, Y-W|Guha, R|Miyamoto, S|Pommier, Y|Caplen, N J
PMID: 21834757
Journal: J Med Chem. 2011 Sep 22;54(18):6177-82.
Title: Cancer selective metallocenedicarboxylates of the fungal cytotoxin illudin M.
Author: Schobert, Rainer|Seibt, Sebastian|Mahal, Katharina|Ahmad, Aamir|Biersack, Bernhard|Effenberger-Neidnicht, Katharina|Padhye, Subhash|Sarkar, Fazlul H|Mueller, Thomas
PMID: 21848340
Journal: PLoS One. 2011;6(8):e23381.
Title: An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression.
Author: Leushacke, Marc|Sporle, Ralf|Bernemann, Christof|Brouwer-Lehmitz, Antje|Fritzmann, Johannes|Theis, Mirko|Buchholz, Frank|Herrmann, Bernhard G|Morkel, Markus
PMID: 21853123
Journal: J Biomed Sci. 2011 Aug 22;18:61.
Title: JNK suppression is essential for 17beta-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells.
Author: Hsu, Hsi-Hsien|Hu, Wei-Syun|Lin, Yueh-Min|Kuo, Wei-Wen|Chen, Li-Mien|Chen, Wei-Kung|Hwang, Jin-Ming|Tsai, Fuu-Jen|Liu, Chung-Jung|Huang, Chih-Yang
PMID: 21859479
Journal: Oncol Res. 2011;19(7):311-21.
Title: 5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.
Author: Mohapatra, Purusottam|Preet, Ranjan|Choudhuri, Maitrayee|Choudhuri, Tathagata|Kundu, Chanakya Nath
PMID: 21936401
Journal: Int J Mol Epidemiol Genet. 2011;2(4):328-38. Epub 2011 Oct 20.
Title: Tumor necrosis factor-related genes and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Bondurant, Kristina L|Wolff, Roger K
PMID: 22199996
Journal: Mol Carcinog. 2012 Jun;51(6):475-90.
Title: Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells.
Author: Babykutty, Suboj|S, Priya P|J, Nandini R|Kumar, M A Suresh|Nair, Mangalam S|Srinivas, Priya|Gopala, Srinivas
PMID: 21678498
Journal: Int J Cancer. 2012 May 1;130(9):1981-90.
Title: The protective role of polymorphism MKK4-1304 T>G in nasopharyngeal carcinoma is modulated by Epstein-Barr virus' infection status.
Author: Zheng, Jian|Liu, Bin|Zhang, Liyuan|Jiang, Lan|Huang, Binfang|You, Yonghe|Jiang, Qingping|Zhang, Shuxu|Lu, Jiachun|Zhou, Yifeng
PMID: 21702039
Journal: Mol Carcinog. 2012 Nov;51(11):869-80.
Title: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author: Park, Heesook|Kim, Minhee|Kwon, Gyoo Taik|Lim, Do Young|Yu, Rina|Sung, Mi-Kyung|Lee, Ki Won|Daily, James W 3rd|Park, Jung Han Yoon
PMID: 21919080
Journal: Cell Death Differ. 2012 Mar;19(3):523-33.
Title: Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells.
Author: Mazurek, N|Byrd, J C|Sun, Y|Hafley, M|Ramirez, K|Burks, J|Bresalier, R S
PMID: 21941373
Journal: Arch Toxicol. 2012 Feb;86(2):329-37.
Title: Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
Author: Donauer, Julia|Schreck, Ilona|Liebel, Urban|Weiss, Carsten
PMID: 21983885
Journal: Acta Neuropathol. 2012 May;123(5):711-25.
Title: Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.
Author: Rogers, Hazel A|Kilday, John-Paul|Mayne, Cerys|Ward, Jennifer|Adamowicz-Brice, Martyna|Schwalbe, Ed C|Clifford, Steven C|Coyle, Beth|Grundy, Richard G
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Journal: Oncol Rep. 2012 Mar;27(3):727-33.
Title: Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells.
Author: Nassar, Zeyad D|Aisha, Abdalrahim F A|Idris, Norshirin|Khadeer Ahamed, Mohamed B|Ismail, Zhari|Abu-Salah, Khalid M|Alrokayan, Salman A|Shah Abdul Majid, Amin Malik
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Journal: Oncogene. 2012 Sep 13;31(37):4095-106.
Title: Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel.
Author: Sidler, D|Brockmann, A|Mueller, J|Nachbur, U|Corazza, N|Renzulli, P|Hemphill, A|Brunner, T
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Journal: Toxicol In Vitro. 2012 Mar;26(2):258-68.
Title: Selenite-induced apoptosis and autophagy in colon cancer cells.
Author: Kralova, Vera|Benesova, Sona|Cervinka, Miroslav|Rudolf, Emil
PMID: 22200533
Journal: Tumour Biol. 2012 Aug;33(4):985-94.
Title: PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Author: Qing, Haitao|Gong, Wei|Che, Yufang|Wang, Xinying|Peng, Liang|Liang, Yan|Wang, Weifei|Deng, Qiliang|Zhang, Hongquan|Jiang, Bo
PMID: 22252525
Journal: J Cell Physiol. 2012 Nov;227(11):3648-60.
Title: p38alpha MAPK mediates 17beta-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells.
Author: Hsu, Hsi-Hsien|Liu, Chung-Jung|Shen, Chia-Yao|Chen, Yi-Jyun|Chen, Li-Mien|Kuo, Wu-Hsien|Lin, Yueh-Min|Chen, Ray-Jade|Tsai, Chang-Hai|Tsai, Fuu-Jen|Huang, Chih-Yang
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Journal: Int J Biochem Cell Biol. 2012 Jun;44(6):896-904.
Title: p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Author: Park, Ji-Young|Song, Ji-Young|Kim, Hyun Mi|Han, Hye-Sook|Seol, Hyang Sook|Jang, Se Jin|Choi, Jene
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Journal: Carcinogenesis. 2012 Jun;33(6):1231-8.
Title: Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice.
Author: Li, Yinghui|Kundu, Parag|Seow, Shih Wee|de Matos, Cristina Teixeira|Aronsson, Linda|Chin, Keh Chuang|Karre, Klas|Pettersson, Sven|Greicius, Gediminas
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Journal: J Biomed Sci. 2012 Mar 30;19:35.
Title: STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death.
Author: Huang, Duen-Yi|Chao, Yee|Tai, Ming-Hui|Yu, Yang-Hao|Lin, Wan-Wan
PMID: 22462553
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
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Journal: J Surg Oncol. 2012 Nov;106(6):689-95.
Title: Hyperthermia synergizes with tissue factor knockdown to suppress the growth and hepatic metastasis of colorectal cancer in orthotopic tumor model.
Author: Li, Hui|Tian, Mao-Lin|Yu, Ge|Liu, Yu-Cun|Wang, Xin|Zhang, Jing|Ji, Shi-Qi|Zhu, Jing|Wan, Yuan-Lian|Tang, Jian-Qiang
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Journal: PLoS One. 2012;7(4):e36006.
Title: Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells.
Author: Tseng, Ho-Hsing|Chuah, Qiu-Yu|Yang, Pei-Ming|Chen, Chiung-Tong|Chao, Jung-Chi|Lin, Ming-Der|Chiu, Shu-Jun
PMID: 22563433
Journal: Food Funct. 2012 Aug;3(8):844-52.
Title: Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway.
Author: Xavier, Cristina P R|Lima, Cristovao F|Fernandes-Ferreira, Manuel|Pereira-Wilson, Cristina
PMID: 22596086
Journal: PPAR Res. 2012;2012:269751.
Title: AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells.
Author: Cerbone, Angelo|Toaldo, Cristina|Pizzimenti, Stefania|Pettazzoni, Piergiorgio|Dianzani, Chiara|Minelli, Rosalba|Ciamporcero, Eric|Roma, Guglielmo|Dianzani, Mario Umberto|Canaparo, Roberto|Ferretti, Carlo|Barrera, Giuseppina
PMID: 22619672
Journal: BMC Cancer. 2012 Jun 8;12:228.
Title: Snake venom toxin from Vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression.
Author: Park, Mi Hee|Jo, MiRan|Won, Dohee|Song, Ho Sueb|Han, Sang Bae|Song, Min Jong|Hong, Jin Tae
PMID: 22681760
Journal: Oncol Rep. 2012 Sep;28(3):931-6.
Title: Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas.
Author: Nomura, Miyuki|Shiiba, Ken-Ichi|Katagiri, Chiaki|Kasugai, Isao|Masuda, Kouhei|Sato, Ikuro|Sato, Masayuki|Kakugawa, Yoichiro|Nomura, Eiki|Hayashi, Katsuhisa|Nakamura, Yoshihiro|Nagata, Toshiyuki|Otsuka, Tsunayuki|Katakura, Ryuichi|Yamashita, Yoji|Sato, Mas
PMID: 22711061
Journal: Chembiochem. 2012 Jul 23;13(11):1663-72.
Title: DYZ-2-90, a novel neo-tanshinlactone ring-opened compound, induces ERK-mediated mitotic arrest and subsequent apoptosis by activating JNK in human colorectal cancer cells.
Author: Wang, Li-Ting|Pan, Shiow-Lin|Chen, Tzu-Hsuan|Dong, Yizhou|Lee, Kuo-Hsiung|Teng, Che-Ming
PMID: 22761044
Journal: PLoS One. 2012;7(6):e40149.
Title: Rosiglitazone and AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cells.
Author: Cerbone, Angelo|Toaldo, Cristina|Minelli, Rosalba|Ciamporcero, Eric|Pizzimenti, Stefania|Pettazzoni, Piergiorgio|Roma, Guglielmo|Dianzani, Mario Umberto|Ullio, Chiara|Ferretti, Carlo|Dianzani, Chiara|Barrera, Giuseppina
PMID: 22761953
Journal: Biol Pharm Bull. 2012;35(7):1054-63.
Title: (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation.
Author: Hong, Ji-Young|Boo, Hye-Jin|Kang, Jung-Il|Kim, Min-Kyoung|Yoo, Eun-Sook|Hyun, Jin-Won|Koh, Young-Sang|Kim, Gi Young|Maeng, Young Hee|Hyun, Chang Lim|Chang, Weon Young|Kim, Young Ho|Kim, Young Ree|Kang, Hee-Kyoung
PMID: 22791152
Journal: BMC Cancer. 2012 Aug 1;12:331.
Title: A systems biology approach to the global analysis of transcription factors in colorectal cancer.
Author: Pradhan, Meeta P|Prasad, Nagendra K A|Palakal, Mathew J
PMID: 22852817
Journal: PLoS One. 2012;7(7):e42253.
Title: Transcriptional regulation of PES1 expression by c-Jun in colon cancer.
Author: Xie, Wei|Feng, Qin|Su, Yahui|Dong, Bin|Wu, Jian|Meng, Lin|Qu, Like|Shou, Chengchao
PMID: 22860098
Journal: PLoS One. 2012;7(8):e41763.
Title: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer.
Author: Zhu, Ming Ming|Tong, Jin Lu|Xu, Qi|Nie, Fang|Xu, Xi Tao|Xiao, Shu Dong|Ran, Zhi Hua
PMID: 22870247
Journal: Cell Cycle. 2012 Sep 1;11(17):3312-23.
Title: Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
Author: Cheng, Hairong|Hong, Bo|Zhou, Lanlan|Allen, Joshua E|Tai, Guihua|Humphreys, Robin|Dicker, David T|Liu, Yingqiu Y|El-Deiry, Wafik S
PMID: 22895172
Journal: PLoS One. 2012;7(8):e43236.
Title: Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers.
Author: Ishida, Kazushige|Nishizuka, Satoshi S|Chiba, Takehiro|Ikeda, Miyuki|Kume, Kohei|Endo, Fumitaka|Katagiri, Hirokatsu|Matsuo, Teppei|Noda, Hironobu|Iwaya, Takeshi|Yamada, Noriyuki|Fujiwara, Hisataka|Takahashi, Masanori|Itabashi, Tetsuya|Uesugi, Noriyuki|Mae
PMID: 22905237
Journal: Free Radic Biol Med. 2012 Nov 15;53(10):1977-87.
Title: Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Author: Sung, Bokyung|Prasad, Sahdeo|Ravindran, Jayaraj|Yadav, Vivek R|Aggarwal, Bharat B
PMID: 22922338
Journal: Int J Oncol. 2012 Nov;41(5):1744-50.
Title: Induction of LGR5 by H2O2 treatment is associated with cell proliferation via the JNK signaling pathway in colon cancer cells.
Author: Kim, Sung-Hee|Kim, Kyung-Hee|Yoo, Byong-Chul|Ku, Ja-Lok
PMID: 22923033
Journal: BioData Min. 2012 Aug 28;5(1):11.
Title: Murine colon proteome and characterization of the protein pathways.
Author: Magdeldin, Sameh|Yoshida, Yutaka|Li, Huiping|Maeda, Yoshitaka|Yokoyama, Munesuke|Enany, Shymaa|Zhang, Ying|Xu, Bo|Fujinaka, Hidehiko|Yaoita, Eishin|Sasaki, Sei|Yamamoto, Tadashi
PMID: 22929016
Journal: Carcinogenesis. 2012 Dec;33(12):2398-408.
Title: MAP kinase genes and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Wolff, Roger K
PMID: 23027623
Journal: PLoS One. 2012;7(9):e44132.
Title: Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species.
Author: Verdoodt, Berlinda|Vogt, Markus|Schmitz, Inge|Liffers, Sven-Thorsten|Tannapfel, Andrea|Mirmohammadsadegh, Alireza
PMID: 23028492
Journal: Mol Cancer Res. 2012 Dec;10(12):1567-79.
Title: The role of Bcl-xL in synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia on human colon cancer.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 23051936
Journal: Mol Biol Rep. 2012 Dec;39(12):10895-902.
Title: Monocytes expression of IL-12 related and IL-10 genes in association with development of colorectal cancer.
Author: Stanilov, Noyko S|Miteva, Lyuba D|Dobreva, Zlatka G|Jovchev, Jovcho P|Cirovski, Geo M|Stanilova, Spaska A
PMID: 23053983
Journal: J Biomed Sci. 2012 Oct 25;19:91.
Title: CXC chemokine ligand 12/stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1.
Author: Tung, Shui-Yi|Chang, Shun-Fu|Chou, Ming-Hui|Huang, Wen-Shih|Hsieh, Yung-Yu|Shen, Chien-Heng|Kuo, Hsing-Chun|Chen, Cheng-Nan
PMID: 23098564
Journal: J Agric Food Chem. 2012 Dec 26;60(51):12451-7.
Title: Silibinin inhibits the invasion of IL-6-stimulated colon cancer cells via selective JNK/AP-1/MMP-2 modulation in vitro.
Author: Lin, Chiu-Mei|Chen, Yen-Hsu|Ma, Hon-Ping|Wang, Bao-Wei|Chiu, Jen-Hwey|Chua, Su-Kiat|Ong, Jiann-Ruey|Shyu, Kou-Gi
PMID: 23210512
Journal: PLoS One. 2012;7(12):e52869.
Title: Butyrate produced by commensal bacteria potentiates phorbol esters induced AP-1 response in human intestinal epithelial cells.
Author: Nepelska, Malgorzata|Cultrone, Antonietta|Beguet-Crespel, Fabienne|Le Roux, Karine|Dore, Joel|Arulampalam, Vermulugesan|Blottiere, Herve M
PMID: 23300800
Journal: Environ Toxicol. 2013 Sep;28(9):479-88.
Title: Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.
Author: Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Yang, Jai-Sing|Ma, Chia-Yu|Lu, Hsu-Feng|Tang, Nou-Ying|Hsia, Te-Chun|Ho, Heng-Chien|Chung, Jing-Gung
PMID: 21695758
Journal: Mol Carcinog. 2013 Mar;52(3):207-17.
Title: Possible involvement of Wnt11 in colorectal cancer progression.
Author: Nishioka, Mitsuaki|Ueno, Koji|Hazama, Shoichi|Okada, Toshiyuki|Sakai, Kouhei|Suehiro, Yutaka|Okayama, Naoko|Hirata, Hiroshi|Oka, Masaaki|Imai, Kohzoh|Dahiya, Rajvir|Hinoda, Yuji
PMID: 22161723
Journal: Int J Cancer. 2013 Feb 1;132(3):707-16.
Title: Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
Author: Kan, Winnie Lai Ting|Yin, Chun|Xu, Hong Xi|Xu, Gang|To, Kenneth Kin Wah|Cho, Chi Hin|Rudd, John Anthony|Lin, Ge
PMID: 22733377
Journal: J Nutr Biochem. 2013 Apr;24(4):706-12.
Title: Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells.
Author: Xavier, Cristina P R|Lima, Cristovao F|Pedro, Dalila F N|Wilson, Jonathan M|Kristiansen, Karsten|Pereira-Wilson, Cristina
PMID: 22841540
Journal: Int J Cancer. 2013 Apr 1;132(7):1537-46.
Title: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation.
Author: Groschl, Benedikt|Bettstetter, Marcus|Giedl, Christian|Woenckhaus, Matthias|Edmonston, Tina|Hofstadter, Ferdinand|Dietmaier, Wolfgang
PMID: 22965873
Journal: J Nat Med. 2013 Jul;67(3):468-79.
Title: Synergistic anticancer activities of the plant-derived sesquiterpene lactones salograviolide A and iso-seco-tanapartholide.
Author: Salla, Mohamed|Fakhoury, Isabelle|Saliba, Najat|Darwiche, Nadine|Gali-Muhtasib, Hala
PMID: 22976170
Journal: J Gastroenterol. 2013 Mar;48(3):350-9.
Title: Overexpression of galectin-3 enhances migration of colon cancer cells related to activation of the K-Ras-Raf-Erk1/2 pathway.
Author: Wu, Keng-Liang|Huang, Eng-Yen|Jhu, En-Wei|Huang, Ya-Hui|Su, Wen-Hong|Chuang, Pei-Chin|Yang, Kuender D
PMID: 23015305
Journal: Cancer Biol Ther. 2013 Feb;14(2):108-16.
Title: Tumor regression by phenethyl isothiocyanate involves DDB2.
Author: Roy, Nilotpal|Elangovan, Indira|Kopanja, Dragana|Bagchi, Srilata|Raychaudhuri, Pradip
PMID: 23114715
Journal: J Biol Chem. 2013 Jan 18;288(3):1883-95.
Title: c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.
Author: Qu, Chao|Li, Weiquan|Shao, Qiangqiang|Dwyer, Trisha|Huang, Huai|Yang, Tao|Liu, Guofa
PMID: 23223444
Journal: Cancer Lett. 2013 May 1;331(2):183-91.
Title: Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death.
Author: Hong, Sujeong|Hwang, Inhwa|Lee, Yun-Sun|Park, Sangjun|Lee, Won-Keun|Fernandes-Alnemri, Teresa|Alnemri, Emad S|Kim, You-Sun|Yu, Je-Wook
PMID: 23321501
Journal: Int J Oncol. 2013 Apr;42(4):1212-8.
Title: Depletion of JARID1B induces cellular senescence in human colorectal cancer.
Author: Ohta, Katsuya|Haraguchi, Naotsugu|Kano, Yoshihiro|Kagawa, Yoshinori|Konno, Masamitsu|Nishikawa, Shimpei|Hamabe, Atsushi|Hasegawa, Shinichiro|Ogawa, Hisataka|Fukusumi, Takahito|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsun
PMID: 23354547
Journal: J Transl Med. 2013 Feb 8;11:32.
Title: Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: hirsutanol A inhibits tumor growth through ROS production.
Author: Yang, Fen|Chen, Wen-Dan|Deng, Rong|Zhang, Hui|Tang, Jun|Wu, Ke-Wei|Li, Dan-Dan|Feng, Gong-Kan|Lan, Wen-Jian|Li, Hou-Jin|Zhu, Xiao-Feng
PMID: 23394457
Journal: PLoS One. 2013;8(2):e56369.
Title: Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling.
Author: Bodur, Cagri|Kutuk, Ozgur|Karsli-Uzunbas, Gizem|Isimjan, Tayirjan T|Harrison, Paul|Basaga, Huveyda
PMID: 23441183
Journal: J Agric Food Chem. 2013 Mar 20;61(11):2811-9.
Title: P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo.
Author: Chen, Li-Ching|Lee, Wen-Sen
PMID: 23448150
Journal: Apoptosis. 2013 Jun;18(6):739-50.
Title: The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.
Author: Beranova, Lenka|Pombinho, Antonio R|Spegarova, Jarmila|Koc, Michal|Klanova, Magdalena|Molinsky, Jan|Klener, Pavel|Bartunek, Petr|Andera, Ladislav
PMID: 23456623
Journal: PLoS One. 2013;8(3):e58606.
Title: Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells.
Author: Zhang, Yong-guo|Wu, Shaoping|Xia, Yinglin|Sun, Jun
PMID: 23505542
Journal: Dev Biol. 2013 Jun 15;378(2):122-40.
Title: APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression.
Author: Wang, Chenhui|Zhao, Rui|Huang, Pin|Yang, Fu|Quan, Zhenghui|Xu, Na|Xi, Rongwen
PMID: 23570874
Journal: Evid Based Complement Alternat Med. 2013;2013:231874.
Title: Oyaksungisan, a Traditional Herbal Formula, Inhibits Cell Proliferation by Induction of Autophagy via JNK Activation in Human Colon Cancer Cells.
Author: Yim, Nam-Hui|Jung, Young Pil|Kim, Aeyung|Ma, Choong Je|Cho, Won-Kyung|Ma, Jin Yeul
PMID: 23573119
Journal: Oncol Rep. 2013 Jul;30(1):292-8.
Title: Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways.
Author: Gao, Jian-Li|Lv, Gui-Yuan|He, Bai-Cheng|Zhang, Bing-Qiang|Zhang, Hongyu|Wang, Ning|Wang, Chong-Zhi|Du, Wei|Yuan, Chun-Su|He, Tong-Chuan
PMID: 23633038
Journal: J Agric Food Chem. 2013 May 22;61(20):4898-904.
Title: Hericium erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice.
Author: Kim, Sung Phil|Nam, Seok Hyun|Friedman, Mendel
PMID: 23668749
Journal: J Cell Biochem. 2013 Oct;114(10):2392-404.
Title: Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer.
Author: Callero, Mariana A|Luzzani, Gabriela A|De Dios, Diana O|Bradshaw, Tracey D|Perez, Andrea I Loaiza
PMID: 23696052
Journal: Cell Signal. 2013 Oct;25(10):1993-2002.
Title: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.
Author: Chen, Min-Bin|Zhang, Yan|Wei, Mu-Xin|Shen, Wei|Wu, Xiao-Yang|Yao, Chen|Lu, Pei-Hua
PMID: 23712032
Journal: Int J Oncol. 2013 Aug;43(2):629-37.
Title: Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Author: Chen, Hui-Jye|Lin, Chung-Ming|Lee, Chao-Ying|Shih, Nai-Chen|Amagaya, Sakae|Lin, Yung-Chang|Yang, Jai-Sing
PMID: 23754208
Journal: Zhonghua Yi Xue Za Zhi. 2013 Mar 12;93(10):746-50.
Title: [Expression and clinicopathological significance of serine-257/threonine-261 phosphorylated MKK4 in colorectal carcinoma].
Author: Huang, Mei-jin|Wang, Pu-ning|Huang, Jun|Zhang, Xing-wei|Wang, Lei|Liu, Huan-liang|Wang, Jian-ping
PMID: 23755811
Journal: Toxicol Lett. 2013 Jul 31;221(1):23-30.
Title: MCM-2 is a therapeutic target of Trichostatin A in colon cancer cells.
Author: Liu, Yangbo|He, Gang|Wang, Yan|Guan, Xinging|Pang, Xueli|Zhang, Bo
PMID: 23770000
Journal: Neoplasia. 2013 Jul;15(7):783-94.
Title: Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma.
Author: Weirauch, Ulrike|Beckmann, Nadine|Thomas, Maren|Grunweller, Arnold|Huber, Kilian|Bracher, Franz|Hartmann, Roland K|Aigner, Achim
PMID: 23814490
Journal: Int J Mol Med. 2013 Sep;32(3):703-8.
Title: Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells.
Author: Tajitsu, Yusuke|Ikeda, Ryuji|Nishizawa, Yukihiko|Mataki, Hirofumi|Che, Xiao-Fang|Sumizawa, Tomoyuki|Nitta, Mina|Yamaguchi, Tatsuya|Yamamoto, Masatatsu|Tabata, Sho|Akiyama, Shin-Ichi|Yamada, Katsushi|Furukawa, Tatsuhiko|Takeda, Yasuo
PMID: 23820674
Journal: J Inorg Biochem. 2013 Oct;127:24-38.
Title: The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph3PAu[SC(OR)=NPh] (R=Me, Et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways.
Author: Yeo, Chien Ing|Ooi, Kah Kooi|Akim, Abdah Md|Ang, Kok Pian|Fairuz, Zainal Abidin|Halim, Siti Nadiah Binti Abdul|Ng, Seik Weng|Seng, Hoi-Ling|Tiekink, Edward R T
PMID: 23850666
Journal: Nutr Cancer. 2013;65(5):718-28.
Title: Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.
Author: Cordero-Herrera, Isabel|Martin, Maria Angeles|Bravo, Laura|Goya, Luis|Ramos, Sonia
PMID: 23859040
Journal: Nutr Cancer. 2013;65(5):729-38.
Title: Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Wolff, Roger K
PMID: 23859041
Journal: Apoptosis. 2013 Nov;18(11):1391-402.
Title: Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress.
Author: Cao, Aili|Li, Qi|Yin, Peihao|Dong, Yang|Shi, Hailian|Wang, Li|Ji, Guang|Xie, Jianqun|Wu, Dazheng
PMID: 23881281
Journal: Anticancer Res. 2013 Aug;33(8):3225-31.
Title: 15,16-Dihydrotanshinone I-induced apoptosis in human colorectal cancer cells: involvement of ATF3.
Author: Suk, Fat-Moon|Jou, Wen-Ju|Lin, Ren-Jye|Lin, Shyr-Yi|Tzeng, Fang-Yu|Liang, Yu-Chih
PMID: 23898083
Journal: Int J Oncol. 2013 Oct;43(4):1235-43.
Title: Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways.
Author: Lin, Jiumao|Chen, Youqin|Wei, Lihui|Shen, Aling|Sferra, Thomas J|Hong, Zhenfeng|Peng, Jun
PMID: 23900560
Journal: Cell Death Dis. 2013 Aug 1;4:e750.
Title: A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells.
Author: Kim, A D|Kang, K A|Kim, H S|Kim, D H|Choi, Y H|Lee, S J|Kim, H S|Hyun, J W
PMID: 23907464
Journal: Biochimie. 2013 Nov;95(11):2157-67.
Title: Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.
Author: Reyes-Zurita, Fernando J|Rufino-Palomares, Eva E|Medina, Pedro P|Leticia Garcia-Salguero, E|Peragon, Juan|Cascante, Marta|Lupianez, Jose A
PMID: 23973282
Journal: Int J Oncol. 2013 Nov;43(5):1560-8.
Title: Receptor-like protein tyrosine phosphatase kappa negatively regulates the apoptosis of prostate cancer cells via the JNK pathway.
Author: Sun, Ping-Hui|Ye, Lin|Mason, Malcolm D|Jiang, Wen G
PMID: 24002526
Journal: Cancer Biol Ther. 2013 Nov;14(11):1007-15.
Title: Mitogen-activated protein kinase phosphatase-1 inhibition and sustained extracellular signal-regulated kinase 1/2 activation in camptothecin-induced human colon cancer cell death.
Author: Lee, Minyoung|Young Kim, Sun|Kim, Jongguk|Kim, Hak-Su|Kim, Sang-Man|Kim, Eun Ju
PMID: 24005240
Journal: PLoS One. 2013 Aug 27;8(8):e73654.
Title: Evidence for two modes of synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia in human colon cancer cells.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 24013390
Journal: PLoS One. 2013 Sep 4;8(9):e73151.
Title: Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.
Author: Drago, Eric|Bordonaro, Michael|Lee, Seon|Atamna, Wafa|Lazarova, Darina L
PMID: 24023824
Journal: Biochem Biophys Res Commun. 2013 Oct 11;440(1):179-83.
Title: MUC1 activates JNK1 and inhibits apoptosis under genotoxic stress.
Author: Chen, Qiongqiong|Li, Decai|Ren, Jian|Li, Chenghua|Xiao, Zhi-Xiong
PMID: 24055030
Journal: Cell Death Dis. 2013 Oct 3;4:e830.
Title: Asymmetric dimethylarginine attenuates serum starvation-induced apoptosis via suppression of the Fas (APO-1/CD95)/JNK (SAPK) pathway.
Author: Li, H|Zhou, Y|Zhao, A|Qiu, Y|Xie, G|Jiang, Q|Zheng, X|Zhong, W|Sun, X|Zhou, Z|Jia, W
PMID: 24091673
Journal: Acta Pharmacol Sin. 2013 Dec;34(12):1535-44.
Title: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway.
Author: Wang, Hai-jun|Liu, Yu|Fan, Li-qiao|Han, Cai-li|Jiang, Ye|Cheng, Shu-jie|Li, Yong
PMID: 24241351
Journal: Oncogene. 2014 Mar 27;33(13):1658-69.
Title: Cadherin-17 interacts with alpha2beta1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis.
Author: Bartolome, R A|Barderas, R|Torres, S|Fernandez-Acenero, M J|Mendes, M|Garcia-Foncillas, J|Lopez-Lucendo, M|Casal, J I
PMID: 23604127
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36.
Title: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.
Author: Zhang, Jingjing|Dou, Wei|Zhang, Eryun|Sun, Aning|Ding, Lili|Wei, Xiaohui|Chou, Guixin|Mani, Sridhar|Wang, Zhengtao
PMID: 24232001
Journal: Cancer Prev Res (Phila). 2014 Jan;7(1):139-49.
Title: Licochalcone A, a natural inhibitor of c-Jun N-terminal kinase 1.
Author: Yao, Ke|Chen, Hanyong|Lee, Mee-Hyun|Li, Haitao|Ma, Weiya|Peng, Cong|Song, Nu Ry|Lee, Ki Won|Bode, Ann M|Dong, Ziming|Dong, Zigang
PMID: 24253317
Journal: Mol Pharmacol. 2014 Mar;85(3):451-9.
Title: Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.
Author: Trondl, Robert|Flocke, Lea S|Kowol, Christian R|Heffeter, Petra|Jungwirth, Ute|Mair, Georg E|Steinborn, Ralf|Enyedy, Eva A|Jakupec, Michael A|Berger, Walter|Keppler, Bernhard K
PMID: 24378333
Journal: Anticancer Agents Med Chem. 2014;14(7):1051-61.
Title: ent-kaurane diterpenoids from Croton tonkinensis induce apoptosis in colorectal cancer cells through the phosphorylation of JNK mediated by reactive oxygen species and dual-specificity JNK kinase MKK4.
Author: Thuong, Phuong Thien|Khoi, Nguyen Minh|Ohta, Saho|Shiota, Shinichiro|Kanta, Hironori|Takeuchi, Kenji|Ito, Fumiaki
PMID: 24476312
Journal: Cancer Sci. 2014 Apr;105(4):425-30.
Title: MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells.
Author: Sakai, Hiroaki|Sato, Ai|Aihara, Yuki|Ikarashi, Yoshinori|Midorikawa, Yutaka|Kracht, Michael|Nakagama, Hitoshi|Okamoto, Koji
PMID: 24533778
Journal: Pharm Biol. 2014 Sep;52(9):1158-65.
Title: Diterpenoid C of Radix Curcumae: an inhibitor of proliferation and inducer of apoptosis in human colon adenocarcinoma cells acting via inhibiting MAPK signaling pathway.
Author: Shen, Yan|Lu, Bin|Zhang, Shuo|Ma, Zhong-Jun
PMID: 24646305
Journal: Sci Rep. 2014 Apr 15;4:4694.
Title: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy.
Author: Sui, Xinbing|Kong, Na|Wang, Xian|Fang, Yong|Hu, Xiaotong|Xu, Yinghua|Chen, Wei|Wang, Kaifeng|Li, Da|Jin, Wei|Lou, Fang|Zheng, Yu|Hu, Hong|Gong, Liu|Zhou, Xiaoyun|Pan, Hongming|Han, Weidong
PMID: 24733045
Journal: Stem Cells Dev. 2014 Aug 15;23(16):1870-82.
Title: Netrin-1 induces MMP-12-dependent E-cadherin degradation via the distinct activation of PKCalpha and FAK/Fyn in promoting mesenchymal stem cell motility.
Author: Lee, Sei-Jung|Jung, Young Hyun|Oh, Sang Yub|Yong, Min Sik|Ryu, Jung Min|Han, Ho Jae
PMID: 24738865
Journal: Tumour Biol. 2014 Jul;35(7):7035-45.
Title: AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells.
Author: Shi, Xiaoming|Wu, Shengchun|Yang, Yongbin|Tang, Lei|Wang, Yuexin|Dong, Junjie|Lu, Bonan|Jiang, Guangwei|Zhao, Wei
PMID: 24752576
Journal: Chem Biol Interact. 2014 Jul 25;218:42-9.
Title: Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells.
Author: Lin, Mei-Hsiang|Cheng, Chia-Hsiung|Chen, Ku-Chung|Lee, Wai-Theng|Wang, Yen-Fang|Xiao, Cai-Qin|Lin, Cheng-Wei
PMID: 24812029
Journal: J Cancer. 2014 Apr 25;5(6):406-16.
Title: Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms.
Author: Doudican, Nicole A|Mazumder, Amitabha|Kapoor, Shweta|Sultana, Zeba|Kumar, Ansu|Talawdekar, Anay|Basu, Kabya|Agrawal, Ashish|Aggarwal, Aditi|Shetty, Krithika|Singh, Neeraj K|Kumar, Chandan|Tyagi, Anuj|Singh, Neeraj Kumar|Darlybai, Janitha C|Abbasi, Taher|V
PMID: 24847381
Journal: Int J Mol Sci. 2014 May 22;15(5):9103-16.
Title: Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Author: Liang, Zengenni|Yi, Youjin|Guo, Yutong|Wang, Rencai|Hu, Qiulong|Xiong, Xingyao
PMID: 24857920
Journal: PLoS One. 2014 Jun 5;9(6):e99257.
Title: Disruption of interleukin-1beta autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Author: Clauzure, Mariangeles|Valdivieso, Angel G|Massip Copiz, Maria M|Schulman, Gustavo|Teiber, Maria Luz|Santa-Coloma, Tomas A
PMID: 24901709
Journal: Oncotarget. 2014 Jun 15;5(11):3590-606.
Title: HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.
Author: Ramirez, Alberto|Boulaiz, Houria|Morata-Tarifa, Cynthia|Peran, Macarena|Jimenez, Gema|Picon-Ruiz, Manuel|Agil, Ahmad|Cruz-Lopez, Olga|Conejo-Garcia, Ana|Campos, Joaquin M|Sanchez, Ana|Garcia, Maria A|Marchal, Juan A
PMID: 24946763
Journal: Oncol Lett. 2014 Jul;8(1):313-316.
Title: Anticancer activities of sulindac in prostate cancer cells associated with c-Jun NH2-terminal kinase 1/beta-catenin signaling.
Author: DU, Jun|Guo, Yongchen|Bao, Yonghua|Xing, Mengtao|Mahmoud, Abeer M|Che, Zhenyong|Chen, Zhiguo|Yang, Wancai
PMID: 24959268
Journal: PLoS One. 2014 Jun 24;9(6):e99729.
Title: Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine.
Author: Chien, Chih-Chiang|Wu, Ming-Shun|Shen, Shing-Chuan|Ko, Ching-Huai|Chen, Chih-Hung|Yang, Ling-Ling|Chen, Yen-Chou
PMID: 24959718
Journal: Biochim Biophys Acta. 2014 Nov;1843(11):2645-61.
Title: Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite.
Author: Rakshit, Srabanti|Chandrasekar, Bhagawat S|Saha, Banishree|Victor, Emmanuel S|Majumdar, Shamik|Nandi, Dipankar
PMID: 24983769
Journal: Biomed Pharmacother. 2014 Jun;68(5):527-35.
Title: NF-kappaB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Author: Li, Meng|Wang, Xiu'e|Liu, Ming|Qi, Xin|Li, Jing
PMID: 24986326
Journal: Biomed Res Int. 2014;2014:175247.
Title: p53 is a key regulator for osthole-triggered cancer pathogenesis.
Author: Huang, Ssu-Ming|Tsai, Cheng-Fang|Chen, Dar-Ren|Wang, Min-Ying|Yeh, Wei-Lan
PMID: 25013761
Journal: J Cell Biochem. 2014 Dec;115(12):2133-45.
Title: Molecular mechanisms associated with PTHrP-induced proliferation of colon cancer cells.
Author: Martin, Maria Julia|Calvo, Natalia|de Boland, Ana Russo|Gentili, Claudia
PMID: 25053227
Journal: Apoptosis. 2014 Oct;19(10):1532-44.
Title: Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway.
Author: Liu, Xiufeng|Qiu, Fan|Liu, Zhipeng|Lan, Yan|Wang, Kai|Zhou, Ping-Kun|Wang, Yao|Hua, Zi-Chun
PMID: 25113506
Journal: Asian Pac J Cancer Prev. 2014;15(15):6321-6.
Title: Activation of JNK/p38 pathway is responsible for alpha-methyl-n-butylshikonin induced mitochondria-dependent apoptosis in SW620 human colorectal cancer cells.
Author: Wang, Hai-Bing|Ma, Xiao-Qiong
PMID: 25124618
Journal: Front Physiol. 2014 Aug 8;5:293.
Title: NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells.
Author: Kuper, Christoph|Beck, Franz-Xaver|Neuhofer, Wolfgang
PMID: 25152734
Journal: PLoS One. 2014 Aug 26;9(8):e104401.
Title: [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling.
Author: Radhakrishnan, E K|Bava, Smitha V|Narayanan, Sai Shyam|Nath, Lekshmi R|Thulasidasan, Arun Kumar T|Soniya, Eppurathu Vasudevan|Anto, Ruby John
PMID: 25157570
Journal: Mol Cancer Ther. 2014 Dec;13(12):3137-51.
Title: miR200c attenuates P-gp-mediated MDR and metastasis by targeting JNK2/c-Jun signaling pathway in colorectal cancer.
Author: Sui, Hua|Cai, Guo-Xiang|Pan, Shu-Fang|Deng, Wan-Li|Wang, Yu-Wei|Chen, Zhe-Sheng|Cai, San-Jun|Zhu, Hui-Rong|Li, Qi
PMID: 25205654
Journal: Biomed Res Int. 2014;2014:413575.
Title: Anticancer activity of marine sponge Hyrtios sp. extract in human colorectal carcinoma RKO cells with different p53 status.
Author: Lim, Hyun Kyung|Bae, Woori|Lee, Hyi-Seung|Jung, Joohee
PMID: 25243139
Journal: PLoS One. 2014 Oct 1;9(10):e109048.
Title: Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach.
Author: Serra, Diana|Rufino, Ana T|Mendes, Alexandrina F|Almeida, Leonor M|Dinis, Teresa C P
PMID: 25271420
Journal: Exp Ther Med. 2014 Nov;8(5):1494-1500.
Title: Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells.
Author: Qu, Lin|Liu, Feng-Xia|Cao, Xiao-Cheng|Xiao, Qiao|Yang, Xiaohong|Ren, Kai-Qun
PMID: 25289048
Journal: Oncol Lett. 2014 Dec;8(6):2591-2596.
Title: Garlic-derived compound S-allylmercaptocysteine inhibits cell growth and induces apoptosis via the JNK and p38 pathways in human colorectal carcinoma cells.
Author: Zhang, Yan|Li, Hong-Yan|Zhang, Zhi-Hua|Bian, Hong-Lei|Lin, Gui
PMID: 25364433
Journal: Biosci Rep. 2014 Dec 12;34(6):e00161.
Title: Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells.
Author: Yu, Xiaojun|Zheng, Bo'an|Chai, Rui
PMID: 25370813
Journal: PLoS One. 2014 Dec 12;9(12):e115170.
Title: Egr-1 activation by cancer-derived extracellular vesicles promotes endothelial cell migration via ERK1/2 and JNK signaling pathways.
Author: Yoon, Yae Jin|Kim, Dae-Kyum|Yoon, Chang Min|Park, Jaesung|Kim, Yoon-Keun|Roh, Tae-Young|Gho, Yong Song
PMID: 25502753
Journal: Free Radic Biol Med. 2014 Oct;75 Suppl 1:S22.
Title: Antioxidants and muscle atrophy in colon cancer: beneficial or deleterious effects?
Author: Derbre, Frederic|Assi, Mohamad|Lefeuvre-Orfila, Luz|Vincent, Sophie|Chevalier, Morgane|Gueritat, Jordan|Salaun, Erwan|Rebillard, Amelie
PMID: 26461307
Journal: Environ Toxicol. 2015 Jul;30(7):852-63.
Title: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling.
Author: Ma, Yi-Shih|Hsiao, Yu-Ping|Lin, Ju-Hwa|Hsu, Shu-Chun|Chueh, Fu-Shin|Weng, Shu-Wen|Lai, Kuang-Chi|Lin, Jaung-Geng|Chung, Jing-Gung
PMID: 24497447
Journal: In Vitro Cell Dev Biol Anim. 2015 Jan;51(1):92-101.
Title: [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.
Author: Ryu, Min Ju|Chung, Ha Sook
PMID: 25148824
Journal: Anat Rec (Hoboken). 2015 Feb;298(2):376-85.
Title: 2-(Pro-1-ynyl)-5-(5,6-dihydroxypenta-1,3-diynyl) thiophene induces apoptosis through reactive oxygen species-mediated JNK activation in human colon cancer SW620 cells.
Author: Xu, Dao Gun|Lv, Wang|Dai, Chun Yan|Zhu, Fan Fan|Xu, Gua Hua|Ma, Zhong Jun|Chen, Zhe
PMID: 25178491
Journal: Pathol Oncol Res. 2015 Apr;21(2):405-11.
Title: The Apoptotic Effect of Plant Based Nanosilver in Colon Cancer Cells is a p53 Dependent Process Involving ROS and JNK Cascade.
Author: Satapathy, Shakti Ranjan|Mohapatra, Purusottam|Das, Dipon|Siddharth, Sumit|Kundu, Chanakya Nath
PMID: 25359126
Journal: Biomol Ther (Seoul). 2015 Jan;23(1):39-44.
Title: Tolfenamic Acid Suppresses Inflammatory Stimuli-Mediated Activation of NF-kappaB Signaling.
Author: Shao, Hong Jun|Lou, Zhiyuan|Jeong, Jin Boo|Kim, Kui Jin|Lee, Jihye|Lee, Seong-Ho
PMID: 25593642
Journal: J Agric Food Chem. 2015 Feb 11;63(5):1540-6.
Title: Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38.
Author: Chen, Ming-Cheng|Lee, Nien-Hung|Hsu, Hsi-Hsien|Ho, Tsung-Jung|Tu, Chuan-Chou|Hsieh, Dennis Jine-Yuan|Lin, Yueh-Min|Chen, Li-Mien|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 25611974
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Cancer Biol Ther. 2015;16(5):733-42.
Title: Differential regulation of autophagy and cell viability by ceramide species.
Author: Cruickshanks, Nichola|Roberts, Jane L|Bareford, M Danielle|Tavallai, Mehrad|Poklepovic, Andrew|Booth, Laurence|Spiegel, Sarah|Dent, Paul
PMID: 25803131
Journal: J Cell Biochem. 2015 Oct;116(10):2227-38.
Title: Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor.
Author: Mizutani, Naoki|Omori, Yukari|Tanaka, Koji|Ito, Hiromi|Takagi, Akira|Kojima, Tetsuhito|Nakatochi, Masahiro|Ogiso, Hideo|Kawamoto, Yoshiyuki|Nakamura, Mitsuhiro|Suzuki, Motoshi|Kyogashima, Mamoru|Tamiya-Koizumi, Keiko|Nozawa, Yoshinori|Murate, Takashi
PMID: 25808826
Journal: Acta Pharmacol Sin. 2015 Apr;36(4):517-27.
Title: Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
Author: Ma, Yi-ming|Han, Wei|Li, Jia|Hu, Li-hong|Zhou, Yu-bo
PMID: 25832431
Journal: Drug Des Devel Ther. 2015 Mar 18;9:1679-89.
Title: Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses.
Author: Xie, Zhaohui|Qu, Yine|Leng, Yanli|Sun, Wenxiu|Ma, Siqi|Wei, Jingbo|Hu, Jiangong|Zhang, Xiaolan
PMID: 25834404
Journal: J Biol Chem. 2015 May 22;290(21):13157-67.
Title: Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
Author: Tirodkar, Tejas S|Lu, Ping|Bai, Aiping|Scheffel, Matthew J|Gencer, Salih|Garrett-Mayer, Elizabeth|Bielawska, Alicja|Ogretmen, Besim|Voelkel-Johnson, Christina
PMID: 25839235
Journal: Oncotarget. 2015 Apr 20;6(11):9061-72.
Title: IL-32alpha suppresses colorectal cancer development via TNFR1-mediated death signaling.
Author: Yun, Hyung-Mun|Park, Kyung-Ran|Kim, Eun-Cheol|Han, Sang Bae|Yoon, Do Young|Hong, Jin Tae
PMID: 25909160
Journal: Br J Pharmacol. 2015 Aug;172(15):3929-43.
Title: Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway.
Author: Xie, Xin|Zhao, Yu|Ma, Chun-Yan|Xu, Xiao-Ming|Zhang, Yan-Qiu|Wang, Chen-Guang|Jin, Jing|Shen, Xin|Gao, Jin-Lai|Li, Na|Sun, Zhi-Jie|Dong, De-Li
PMID: 25953698
Journal: Tumour Biol. 2015 Sep;36(10):7947-60.
Title: gamma-Synuclein confers both pro-invasive and doxorubicin-mediated pro-apoptotic properties to the colon adenocarcinoma LS 174T cell line.
Author: Goh, Kai-Wey|Say, Yee-How
PMID: 25956278
Journal: Bioorg Med Chem Lett. 2015 Jun 15;25(12):2559-64.
Title: Cardamonin induces autophagy and an antiproliferative effect through JNK activation in human colorectal carcinoma HCT116 cells.
Author: Kim, Young-Joo|Kang, Ki Sung|Choi, Kyung-Chul|Ko, Hyeonseok
PMID: 25959811
Journal: Clin Cancer Res. 2015 Sep 15;21(18):4143-52.
Title: Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents.
Author: Vasilevskaya, Irina A|Selvakumaran, Muthu|Hierro, Lucia Cabal|Goldstein, Sara R|Winkler, Jeffrey D|O'Dwyer, Peter J
PMID: 26023085
Journal: Radiother Oncol. 2015 Sep;116(3):510-6.
Title: EGFR and beta1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion.
Author: Poschau, Mandy|Dickreuter, Ellen|Singh-Muller, Jenny|Zscheppang, Katja|Eke, Iris|Liersch, Torsten|Cordes, Nils
PMID: 26096850
Journal: Mol Cancer. 2015 Jun 27;14:123.
Title: NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7.
Author: Banskota, Suhrid|Regmi, Sushil C|Kim, Jung-Ae
PMID: 26116564
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19401-18.
Title: Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Author: Lan, Qiusheng|Li, Shoufeng|Lai, Wei|Xu, Heyang|Zhang, Yang|Zeng, Yujie|Lan, Wenjian|Chu, Zhonghua
PMID: 26287184
Journal: Food Chem Toxicol. 2015 Oct;84:125-32.
Title: Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
Author: Cerezo-Guisado, Maria Isabel|Zur, Rafal|Lorenzo, Maria Jesus|Risco, Ana|Martin-Serrano, Miguel A|Alvarez-Barrientos, Alberto|Cuenda, Ana|Centeno, Francisco
PMID: 26303273
Journal: Int J Oncol. 2015 Oct;47(4):1517-27.
Title: E-cadherin knockdown increases beta-catenin reducing colorectal cancer chemosensitivity only in three-dimensional cultures.
Author: Liang, Xi|Xu, Xueqing|Wang, Fengchao|Chen, Xuedan|Li, Ni|Wang, Cancan|He, Jianming
PMID: 26316041
Journal: PLoS One. 2015 Aug 28;10(8):e0136947.
Title: Roles of TLR/MyD88/MAPK/NF-kappaB Signaling Pathways in the Regulation of Phagocytosis and Proinflammatory Cytokine Expression in Response to E. faecalis Infection.
Author: Zou, Jun|Shankar, Nathan
PMID: 26317438
Journal: J Exp Clin Cancer Res. 2015 Sep 4;34:94.
Title: Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo.
Author: Xun, Cai|Chen, Min-Bin|Qi, Li|Tie-Ning, Zhang|Peng, Xue|Ning, Li|Zhi-Xiao, Chen|Li-Wei, Wang
PMID: 26337959
Journal: Oncotarget. 2015 Sep 29;6(29):27580-95.
Title: Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1.
Author: Lee, Wen-Ying|Lee, Wai-Theng|Cheng, Chia-Hsiung|Chen, Ku-Chung|Chou, Chih-Ming|Chung, Chu-Hung|Sun, Min-Siou|Cheng, Hung-Wei|Ho, Meng-Ni|Lin, Cheng-Wei
PMID: 26363315
Journal: Int J Oncol. 2015 Nov;47(5):1663-71.
Title: Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells.
Author: Wen, Chuangyu|Huang, Lanlan|Chen, Junxiong|Lin, Mengmeng|Li, Wen|Lu, Biyan|Rutnam, Zina Jeyapalan|Iwamoto, Aikichi|Wang, Zhongyang|Yang, Xiangling|Liu, Huanliang
PMID: 26397804
Journal: BMC Complement Altern Med. 2015 Sep 24;15:336.
Title: Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells.
Author: Yim, Nam-Hui|Kim, Aeyung|Jung, Young Pil|Kim, Taesoo|Ma, Choong Je|Ma, Jin Yeul
PMID: 26403976
Journal: Oncotarget. 2015 Nov 10;6(35):38195-209.
Title: Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis.
Author: Nimri, Lili|Saadi, Janan|Peri, Irena|Yehuda-Shnaidman, Einav|Schwartz, Betty
PMID: 26472027
Journal: Mol Med Rep. 2015 Dec;12(6):8062-70.
Title: Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines.
Author: Fang, Feng-Qi|Guo, Hui-Shu|Zhang, Jie|Ban, Li-Ying|Liu, Ji-Wei|Yu, Pei-Yao
PMID: 26498992
Journal: Oncol Lett. 2015 Aug;10(2):709-715.
Title: JNK signaling pathway is involved in piperlongumine-mediated apoptosis in human colorectal cancer HCT116 cells.
Author: Li, Wen|Wen, Chuangyu|Bai, Haiyan|Wang, Xiaoyan|Zhang, Xiaoli|Huang, Lanlan|Yang, Xiangling|Iwamoto, Aikichi|Liu, Huanliang
PMID: 26622558
Journal: Am J Cancer Res. 2015 Oct 15;5(10):3174-85. eCollection 2015.
Title: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice.
Author: Liu, Zhen-Yu|Wu, Bo|Guo, Yun-Shan|Zhou, Ying-Hui|Fu, Zhi-Guang|Xu, Bao-Qing|Li, Jiang-Hua|Jing, Lin|Jiang, Jian-Li|Tang, Juan|Chen, Zhi-Nan
PMID: 26693068
Journal: Cell Biochem Biophys. 2015 Nov;73(2):559-564.
Title: Epieriocalyxin A Induces Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells.
Author: Wang, Zhou|Xu, Zhijie|Niu, Zhengchuan|Liang, Benjia|Niu, Jun
PMID: 27352353
Journal: Gut. 2016 Oct;65(10):1690-701.
Title: New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Author: Qi, Jingjing|Yu, Yong|Akilli Ozturk, Ozlem|Holland, Jane D|Besser, Daniel|Fritzmann, Johannes|Wulf-Goldenberg, Annika|Eckert, Klaus|Fichtner, Iduna|Birchmeier, Walter
PMID: 26156959
Journal: Tumour Biol. 2016 Mar;37(3):3135-44.
Title: Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cells.
Author: Zhou, Chunxian|Chen, Zhengrong|Lu, Xingsheng|Wu, Hao|Yang, Qunying|Xu, Dongfeng
PMID: 26427664
Journal: Cell Death Differ. 2016 Apr;23(4):707-22.
Title: DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.
Author: Alam, S K|Yadav, V K|Bajaj, S|Datta, A|Dutta, S K|Bhattacharyya, M|Bhattacharya, S|Debnath, S|Roy, S|Boardman, L A|Smyrk, T C|Molina, J R|Chakrabarti, S|Chowdhury, S|Mukhopadhyay, D|Roychoudhury, S
PMID: 26494468
Journal: Mol Carcinog. 2016 Nov;55(11):1786-1795.
Title: Oncogenic activin C interacts with decorin in colorectal cancer in vivo and in vitro.
Author: Bi, Xiuli|Xia, Xichun|Fan, Dongdong|Mu, Teng|Zhang, Qiuhua|Iozzo, Renato V|Yang, Wancai
PMID: 26509701
Journal: Oncogene. 2016 Jun 16;35(24):3190-200.
Title: The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
Author: Rey, C|Faustin, B|Mahouche, I|Ruggieri, R|Brulard, C|Ichas, F|Soubeyran, I|Lartigue, L|De Giorgi, F
PMID: 26522728
Journal: Oncol Rep. 2016 Jan;35(1):205-10.
Title: Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway.
Author: Xiang, Tao|Fei, Rushan|Wang, Zhe|Shen, Zhonglei|Qian, Jing|Chen, Wenbin
PMID: 26530054
Journal: Cancer Res. 2016 Feb 1;76(3):724-35.
Title: Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.
Author: Marusiak, Anna A|Stephenson, Natalie L|Baik, Hayeon|Trotter, Eleanor W|Li, Yaoyong|Blyth, Karen|Mason, Susan|Chapman, Phil|Puto, Lorena A|Read, Jon A|Brassington, Claire|Pollard, Hannah K|Phillips, Chris|Green, Isabelle|Overman, Ross|Collier, Matthew|Test
PMID: 26637668
Journal: Dig Dis Sci. 2016 Apr;61(4):1091-7.
Title: AKT and JNK Signaling Pathways Increase the Metastatic Potential of Colorectal Cancer Cells by Altering Transgelin Expression.
Author: Zhou, Huimin|Zhang, Yiming|Chen, Qikui|Lin, Ying
PMID: 26694173
Journal: Oncotarget. 2016 Jan 19;7(3):2878-88.
Title: TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway.
Author: Wang, Shu-Yang|Gao, Ke|Deng, Dan-Ling|Cai, Juan-Juan|Xiao, Zhi-Yuan|He, Liu-Qing|Jiao, Hong-Li|Ye, Ya-Ping|Yang, Run-Wei|Li, Ting-Ting|Liang, Li|Liao, Wen-Ting|Ding, Yan-Qing
PMID: 26701208
Journal: Chin J Integr Med. 2016 Jan 29. pii: 10.1007/s11655-015-2108-3.
Title: Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.
Author: Zhang, Lei-Lei|Si, Jian-Yong|Zhang, Li-Jing|Xiao-Wei, Huo|Lin, Li|Li, Ru-Yi|Chen, Dan|Cao, Li
PMID: 26825081
Journal: Mol Cell Biochem. 2016 Mar;414(1-2):13-22.
Title: GADD45alpha modulates curcumin sensitivity through c-Abl- and JNK-dependent signaling pathways in a mismatch repair-dependent manner.
Author: Naick, Hemanth|Jin, Shunqian|Baskaran, R
PMID: 26833194
Journal: PLoS One. 2016 Feb 22;11(2):e0149822.
Title: The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus.
Author: Teng, Jia-An|Wu, San-Gang|Chen, Jia-Xin|Li, Qiang|Peng, Fang|Zhu, Zhou|Qin, Jian|He, Zhen-Yu
PMID: 26901856
Journal: Mol Nutr Food Res. 2016 May;60(5):1068-78.
Title: Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization.
Author: Byun, Sanguine|Shin, Seung Ho|Park, Jiman|Lim, Semi|Lee, Eunjung|Lee, Chaeyoon|Sung, Dongeun|Farrand, Lee|Lee, Seoung Rak|Kim, Ki Hyun|Dong, Zigang|Lee, Sam W|Lee, Ki Won
PMID: 26918318
Journal: Oncotarget. 2016 Mar 29;7(13):16840-54.
Title: Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells.
Author: Yue, Wenjie|Lin, Yuli|Yang, Xuguang|Li, Bingji|Liu, Jie|He, Rui
PMID: 26919238
Journal: Proteomics. 2016 May;16(10):1557-69.
Title: Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author: Tai, William Chi-Shing|Wong, Wing-Yan|Lee, Magnolia Muk-Lan|Chan, Brandon Dow|Lu, Cheng|Hsiao, Wen-Luan Wendy
PMID: 26970558
Journal: Anticancer Res. 2016 Mar;36(3):1211-9.
Title: Knockdown of EPHA1 by CRISPR/CAS9 Promotes Adhesion and Motility of HRT18 Colorectal Carcinoma Cells.
Author: Wu, B O|Jiang, Wen G|Zhou, Deshan|Cui, Yu-Xin
PMID: 26977017
Journal: Toxicol Appl Pharmacol. 2016 Jun 1;300:1-12.
Title: Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line.
Author: Vendramini-Costa, Debora Barbosa|Alcaide, Antonio|Pelizzaro-Rocha, Karin Juliane|Talero, Elena|Avila-Roman, Javier|Garcia-Maurino, Sofia|Pilli, Ronaldo Aloise|de Carvalho, Joao Ernesto|Motilva, Virginia
PMID: 27016270
Journal: Biochem Biophys Res Commun. 2016 Apr 29;473(2):586-92.
Title: Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
Author: Park, Mi Hee|Kim, Jong Han|Chung, Young-Ho|Lee, Seung Ho
PMID: 27033605
Journal: Cell Oncol (Dordr). 2016 Jun;39(3):287-93.
Title: Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report.
Author: Karatzas, Demetrios N|Xanthopoulos, Konstantinos|Kotantaki, Panorea|Pseftogas, Athanasios|Teliousis, Konstantinos|Hatzivassiliou, Eudoxia G|Kontoyiannis, Dimitris L|Poutahidis, Theofilos|Mosialos, George
PMID: 27042826
Journal: Mar Drugs. 2016 Mar 29;14(4). pii: md14040069.
Title: In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells.
Author: Eo, Hyun Ji|Kwon, Tae-Hyung|Park, Gwang Hun|Song, Hun Min|Lee, Su-Jin|Park, Nyun-Ho|Jeong, Jin Boo
PMID: 27043582
Journal: PLoS One. 2016 Apr 26;11(4):e0154525.
Title: 5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells.
Author: Bhardwaj, Monika|Kim, Na-Hyung|Paul, Souren|Jakhar, Rekha|Han, Jaehong|Kang, Sun Chul
PMID: 27116119
Journal: Oncol Rep. 2016 Jul;36(1):23-30.
Title: Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway.
Author: Zhang, Ying|Lin, Lianjie|Jin, Yu|Lin, Yan|Cao, Yong|Zheng, Changqing
PMID: 27121420
Journal: Oncotarget. 2016 Jun 14;7(24):36842-36853.
Title: Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways.
Author: Lee, Yeo Song|Kim, So-Young|Song, Su Jeong|Hong, Hye Kyung|Lee, Yura|Oh, Bo Young|Lee, Woo Yong|Cho, Yong Beom
PMID: 27167205
Journal: J Steroid Biochem Mol Biol. 2016 Oct;163:164-72.
Title: c-Jun NH2-teminal kinase 1 interacts with vitamin D receptor and affects vitamin D-mediated inhibition of cancer cell proliferation.
Author: Bi, Xiuli|Shi, Qi|Zhang, Huijuan|Bao, Yonghua|Hu, Dong|Pohl, Nicole|Fang, Wenfeng|Dong, Huali|Xia, Xichun|Fan, Dongdong|Yang, Wancai
PMID: 27174721
Journal: Mol Cancer Res. 2016 Aug;14(8):753-63.
Title: JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy.
Author: Vasilevskaya, Irina A|Selvakumaran, Muthu|Roberts, David|O'Dwyer, Peter J
PMID: 27216154
Journal: Antioxid Redox Signal. 2016 Sep 10;25(8):467-84.
Title: Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects.
Author: Paillas, Salome|Ladjohounlou, Riad|Lozza, Catherine|Pichard, Alexandre|Boudousq, Vincent|Jarlier, Marta|Sevestre, Samuel|Le Blay, Marion|Deshayes, Emmanuel|Sosabowski, Jane|Chardes, Thierry|Navarro-Teulon, Isabelle|Mairs, Robert J|Pouget, Jean-Pierre
PMID: 27224059
Journal: J Cancer. 2016 Apr 29;7(8):900-9.
Title: P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer.
Author: He, Jianming|Liang, Xi|Luo, Fen|Chen, Xuedan|Xu, Xueqing|Wang, Fengchao|Zhang, Zhenping
PMID: 27313779
Journal: J Surg Res. 2016 Jun 1;203(1):193-205.
Title: The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway.
Author: Monin, Malte B|Krause, Petra|Stelling, Robin|Bocuk, Derya|Niebert, Sabine|Klemm, Florian|Pukrop, Tobias|Koenig, Sarah
PMID: 27338550
Journal: Oncotarget. 2016 Aug 2;7(31):50057-50073.
Title: Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling.
Author: Xiao, Bin|Chen, Daxiang|Luo, Shuhong|Hao, Wenbo|Jing, Fangyan|Liu, Tiancai|Wang, Suihai|Geng, Yan|Li, Linhai|Xu, Weiwen|Zhang, Yajie|Liao, Xiaoqing|Zuo, Daming|Wu, Yingsong|Li, Ming|Ma, Qiang
PMID: 27367023
Journal: Int J Biol Macromol. 2016 Nov;92:88-95.
Title: Inhibitory effect on HT-29 colon cancer cells of a water-soluble polysaccharide obtained from highland barley.
Author: Cheng, Dai|Zhang, Xinyu|Meng, Meng|Han, Lirong|Li, Caijiao|Hou, Lihua|Qi, Wentao|Wang, Chunling
PMID: 27377460
Journal: Oncotarget. 2016 Jul 26;7(30):48027-48037.
Title: Dragon (RGMb) induces oxaliplatin resistance in colon cancer cells.
Author: Shi, Ying|Huang, Xiao-Xiao|Chen, Guo-Bin|Wang, Ying|Zhi, Qiang|Liu, Yuan-Sheng|Wu, Xiao-Ling|Wang, Li-Fen|Yang, Bing|Xiao, Chuan-Xing|Xing, Hui-Qin|Ren, Jian-Lin|Xia, Yin|Guleng, Bayasi
PMID: 27384995
Journal: Biochem Biophys Res Commun. 2016 Sep 9;478(1):481-485.
Title: Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell.
Author: Ushijima, Hironori|Horyozaki, Akiko|Maeda, Masatomo
PMID: 27404124
Journal: Ann Surg Oncol. 2016 Nov;23(12):3924-3933.
Title: Immature Colon Carcinoma Transcript-1 (ICT1) Expression Correlates with Unfavorable Prognosis and Survival in Patients with Colorectal Cancer.
Author: Lao, Xinyuan|Feng, Qingyang|He, Guodong|Ji, Meiling|Zhu, Dexiang|Xu, Pingping|Tang, Wentao|Xu, Jianmin|Qin, Xinyu
PMID: 27411551
Journal: Food Chem Toxicol. 2016 Sep;95:142-8.
Title: The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3beta-dependent threonine-286 phosphorylation in human colorectal cancer cells.
Author: Park, Gwang Hun|Song, Hun Min|Jeong, Jin Boo
PMID: 27424123
Journal: Int J Mol Sci. 2016 Jul 15;17(7). pii: ijms17071123.
Title: Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells.
Author: Karabay, Arzu Zeynep|Koc, Asli|Ozkan, Tulin|Hekmatshoar, Yalda|Sunguroglu, Asuman|Aktan, Fugen|Buyukbingol, Zeliha
PMID: 27428957
Journal: BMC Cancer. 2016 Jul 20;16:508.
Title: ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.
Author: Ma, Sean S Q|Srivastava, Sameer|Llamosas, Estelle|Hawkins, Nicholas J|Hesson, Luke B|Ward, Robyn L|Ford, Caroline E
PMID: 27440078
Journal: Front Cell Infect Microbiol. 2016 Jun 21;6:68.
Title: Flagellin Induces beta-Defensin 2 in Human Colonic Ex vivo Infection with Enterohemorrhagic Escherichia coli.
Author: Lewis, Steven B|Prior, Alison|Ellis, Samuel J|Cook, Vivienne|Chan, Simon S M|Gelson, William|Schuller, Stephanie
PMID: 27446815
Journal: Protein Cell. 2016 Aug;7(8):571-85.
Title: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author: Shan, Jianzhen|Xuan, Yanyan|Zhang, Qi|Zhu, Chunpeng|Liu, Zhen|Zhang, Suzhan
PMID: 27472952
Journal: Nat Commun. 2016 Aug 10;7:12365.
Title: Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis.
Author: Konishi, Hiroaki|Fujiya, Mikihiro|Tanaka, Hiroki|Ueno, Nobuhiro|Moriichi, Kentaro|Sasajima, Junpei|Ikuta, Katsuya|Akutsu, Hiroaki|Tanabe, Hiroki|Kohgo, Yutaka
PMID: 27507542
Journal: Mol Oncol. 2016 Nov;10(9):1415-1429.
Title: Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells.
Author: Mehdawi, Lubna M|Prasad, Chandra Prakash|Ehrnstrom, Roy|Andersson, Tommy|Sjolander, Anita
PMID: 27522468
Journal: BMC Complement Altern Med. 2016 Aug 15;16(1):288.
Title: Geijigajakyak decoction inhibits the motility and tumorigenesis of colorectal cancer cells.
Author: Lee, Soong-In|Bae, Jeong A|Ko, Yoo-Seung|Lee, Kyoung-In|Kim, Hangun|Kim, Kyung Keun
PMID: 27527352
Journal: Cell Biol Int. 2016 Dec;40(12):1280-1293.
Title: Gene expression profile analysis of dbpA knockdown in colorectal cancer cells.
Author: Liu, Ruiting|Wang, Guorong|Liu, Chang|Qiu, Jian|Yan, Likun|Li, Xiaojun|Wang, Xiaoqiang
PMID: 27569444
Journal: Apoptosis. 2016 Nov;21(11):1291-1301.
Title: Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
Author: Chen, Lei|Meng, Yue|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Zhang, Fenglei|Cheng, Hairong|Zhou, Yifa
PMID: 27629794
Journal: Oncotarget. 2016 Nov 8;7(45):73711-73724.
Title: Lipopolysaccharide increases the release of VEGF-C that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4- NF-kappaB/JNK pathways in colorectal cancer.
Author: Zhu, Guangwei|Huang, Qiang|Huang, Yongjian|Zheng, Wei|Hua, Jin|Yang, Shugang|Zhuang, Jinfu|Wang, Jinzhou|Ye, Jianxin
PMID: 27713159
Journal: Biomed Pharmacother. 2016 Dec;84:789-799.
Title: Novel quercetin derivative TEF induces ER stress and mitochondria-mediated apoptosis in human colon cancer HCT-116 cells.
Author: Khan, Imran|Paul, Souren|Jakhar, Rekha|Bhardwaj, Monika|Han, Jaehong|Kang, Sun Chul
PMID: 27721177
Journal: Food Funct. 2016 Dec 7;7(12):4823-4829.
Title: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells.
Author: Kong, Chang-Suk|Kim, You Ah|Kim, Hojun|Seo, Youngwan
PMID: 27808331
Journal: J Tradit Chin Med. 2016 Aug;36(4):514-21.
Title: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
Author: Shen, Li|Lou, Zhaohuan|Zhang, Guangshun|Xu, Guanhua|Zhang, Guangji
PMID: 28459519
Journal: Environ Toxicol. 2017 Feb;32(2):669-678.
Title: Inhibition of NF-kappaB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
Author: Chen, Ming-Cheng|Lee, Nien-Hung|Hsu, Hsi-Hsien|Ho, Tsung-Jung|Tu, Chuan-Chou|Chen, Ray-Jade|Lin, Yueh-Min|Viswanadha, Vijaya Padma|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 27060453
Journal: Anticancer Drugs. 2017 Jan;28(1):66-74.
Title: Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author: Guo, Xiaoqing|Meng, Yue|Sheng, Xiaotong|Guan, Yuan|Zhang, Fenglei|Han, Zhen|Kang, Yuying|Tai, Guihua|Zhou, Yifa|Cheng, Hairong
PMID: 27603596
Journal: Bioorg Med Chem. 2017 Jan 1;25(1):397-407.
Title: Synthesis and biological evaluation of hesperetin derivatives as agents inducing apoptosis.
Author: Jung, Kang-Yeoun|Park, Jihyun|Han, Young-Sung|Lee, Young Han|Shin, Soon Young|Lim, Yoongho
PMID: 27840137
Journal: Acta Pharmacol Sin. 2017 Feb;38(2):252-263.
Title: Oblongifolin C and guttiferone K extracted from Garcinia yunnanensis fruit synergistically induce apoptosis in human colorectal cancer cells in vitro.
Author: Li, Hui|Meng, Xiao-Xiao|Zhang, Li|Zhang, Bao-Jun|Liu, Xin-Yu|Fu, Wen-Wei|Tan, Hong-Sheng|Lao, Yuan-Zhi|Xu, Hong-Xi
PMID: 27840412
Journal: Int J Mol Med. 2017 Jan;39(1):217-222.
Title: SN38 increases IL-8 expression through the MAPK pathways in HCT8 cells.
Author: Zhang, Lei|Lou, Wen-Hui|Xu, Xue-Feng|Wu, Wenchuan|Rong, Ye-Fei|Jin, Da-Yong
PMID: 27878250
Journal: Oncotarget. 2017 Jan 3;8(1):1678-1687.
Title: p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription.
Author: Zhong, Liang|Simoneau, Bryan|Huot, Jacques|Simard, Martin J
PMID: 27926494
Journal: PLoS One. 2017 Jan 9;12(1):e0168989.
Title: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author: Huang, Wen-Shih|Kuo, Yi-Hung|Kuo, Hsing-Chun|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Lee, Ko-Chao|Lee, Kam-Fai|Shen, Chien-Heng|Tung, Shui-Yi|Teng, Chih-Chuan
PMID: 28068431
Journal: Biomed Pharmacother. 2017 Apr;88:151-161.
Title: 3',5-dihydroxy-3,4',7-trimethoxyflavone-induces ER-stress-associated HCT-116 programmed cell death via redox signaling.
Author: Singh, Mahendra Pal|Han, Jaehong|Kang, Sun Chul
PMID: 28103509
Journal: J Exp Clin Cancer Res. 2017 Jan 23;36(1):16.
Title: MIF/CD74 axis is a target for novel therapies in colon carcinomatosis.
Author: Bozzi, Fabio|Mogavero, Angela|Varinelli, Luca|Belfiore, Antonino|Manenti, Giacomo|Caccia, Claudio|Volpi, Chiara C|Beznoussenko, Galina V|Milione, Massimo|Leoni, Valerio|Gloghini, Annunziata|Mironov, Alexandre A|Leo, Ermanno|Pilotti, Silvana|Pierotti, Marc
PMID: 28114961
Journal: PLoS One. 2017 Jan 26;12(1):e0170595.
Title: Knockdown of NIK and IKKbeta-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-kappaBeta Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.
Author: Qin, Mengbin|Zhang, Jinxiu|Xu, Chunyan|Peng, Peng|Tan, Lin|Liu, Shiquan|Huang, Jiean
PMID: 28125661
Journal: Free Radic Biol Med. 2017 May;106:24-37.
Title: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author: Wang, Gangyang|Zhang, Tao|Sun, Wei|Wang, Hongsheng|Yin, Fei|Wang, Zhuoying|Zuo, Dongqing|Sun, Mengxiong|Zhou, Zifei|Lin, Binhui|Xu, Jing|Hua, Yingqi|Li, Haoqing|Cai, Zhengdong
PMID: 28188923
Journal: BMC Cancer. 2017 Feb 21;17(1):148.
Title: WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice.
Author: Singh, Vijay Pratap|Katta, Saritha|Kumar, Satish
PMID: 28222755
Journal: Cancer Res. 2017 May 15;77(10):2735-2745.
Title: IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment.
Author: Fang, Min|Li, Yongkui|Huang, Kai|Qi, Shanshan|Zhang, Jian|Zgodzinski, Witold|Majewski, Marek|Wallner, Grzegorz|Gozdz, Stanislaw|Macek, Pawel|Kowalik, Artur|Pasiarski, Marcin|Grywalska, Ewelina|Vatan, Linda|Nagarsheth, Nisha|Li, Wei|Zhao, Lili|Kryczek, Ilo
PMID: 28249897
Journal: Nucleosides Nucleotides Nucleic Acids. 2017 Apr 3;36(4):243-255.
Title: Antiproliferation effect of guanosine on HCT 116 cells involves MAPK and AMPK pathways.
Author: Teoh, Wuen Yew|Wahab, Norhanom Abdul|Sim, Kae Shin
PMID: 28323520
Journal: Oncol Rep. 2017 May;37(5):3128-3136.
Title: Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor.
Author: Kawasaki, Hideyoshi|Saotome, Takuya|Usui, Tatsuya|Ohama, Takashi|Sato, Koichi
PMID: 28339087
Journal: J Ethnopharmacol. 2017 May 5;203:27-38.
Title: Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1alpha via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
Author: Mi, Chunliu|Ma, Juan|Wang, Ke Si|Zuo, Hong Xiang|Wang, Zhe|Li, Ming Yue|Piao, Lian Xun|Xu, Guang Hua|Li, Xuezheng|Quan, Zhe Shan|Jin, Xuejun
PMID: 28341244
Journal: Int J Biol Sci. 2017 Feb 12;13(3):286-294.
Title: BEX2 promotes tumor proliferation in colorectal cancer.
Author: Hu, Yeting|Xiao, Qian|Chen, Haiyan|He, Jinjie|Tan, Yinuo|Liu, Yue|Wang, Zhanhuai|Yang, Qi|Shen, Xiangfeng|Huang, Yu|Yuan, Ying|Ding, Kefeng
PMID: 28367093
Journal: Int J Mol Sci. 2017 Apr 6;18(4). pii: ijms18040765.
Title: SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma.
Author: Wang, Yaxi|Sun, Tingyi|Sun, Haimei|Yang, Shu|Li, Dandan|Zhou, Deshan
PMID: 28383479
Journal: Carcinogenesis. 2017 May 1;38(5):559-569.
Title: Inactivation of JNK2 as carcinogenic factor in colitis-associated and sporadic colorectal carcinogenesis.
Author: Lessel, Wiebke|Silver, Andrew|Jechorek, Doerthe|Guenther, Thomas|Roehl, Friedrich-Wilhelm|Kalinski, Thomas|Roessner, Albert|Poehlmann-Nitsche, Angela
PMID: 28383667
Journal: Nutr Res Pract. 2017 Apr;11(2):90-96.
Title: Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells.
Author: Cha, Jae Hoon|Kim, Woo Kyoung|Ha, Ae Wha|Kim, Myung Hwan|Chang, Moon Jeong
PMID: 28386381
Journal: Oncotarget. 2017 May 23;8(21):35033-35047.
Title: A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells.
Author: Mehdawi, Lubna M|Satapathy, Shakti Ranjan|Gustafsson, Annika|Lundholm, Kent|Alvarado-Kristensson, Maria|Sjolander, Anita
PMID: 28402256
Journal: Oncotarget. 2017 Apr 18;8(16):26231-26244.
Title: Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells.
Author: Li, Jun|Ye, Lin|Sun, Ping-Hui|Zheng, Fei|Ruge, Fiona|Satherley, Lucy K|Feng, Yi|Zhao, Huishan|Du, Guifang|Wang, Tingting|Yang, Yao|Ma, Xuemei|Cheng, Shan|Yang, Xiaomei|Yu, Hefen|Teng, Xu|Si, Yang|Zhang, Zhongtao|Jiang, Wen G
PMID: 28412738
Journal: Free Radic Biol Med. 2017 Jul;108:433-444.
Title: Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.
Author: Sun, Wen|Wu, Xiaxia|Gao, Hongwei|Yu, Jie|Zhao, Wenwen|Lu, Jin-Jian|Wang, Jinhua|Du, Guanhua|Chen, Xiuping
PMID: 28414098
Journal: Am J Chin Med. 2017;45(4):901-915.
Title: Vitex rotundifolia Fruit Extract Induces Apoptosis Through the Downregulation of ATF3-Mediated Bcl-2 Expression in Human Colorectal Cancer Cells.
Author: Song, Hun Min|Park, Gwang Hun|Koo, Jin Suk|Jeong, Hyung Jin|Jeong, Jin Boo
PMID: 28468511
Journal: Molecules. 2017 May 6;22(5). pii: molecules22050756.
Title: Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice.
Author: Wang, Canhong|Huo, Xiaowei|Gao, Li|Sun, Guibo|Li, Cao
PMID: 28481246
Journal: J Food Sci. 2017 Jun;82(6):1475-1483.
Title: Apoptotic Activity of Lactobacillus plantarum DGK-17-Fermented Soybean Seed Extract in Human Colon Cancer Cells via ROS-JNK Signaling Pathway.
Author: Khan, Imran|Kang, Sun Chul
PMID: 28488794
Journal: Oncogenesis. 2017 May 22;6(5):e341.
Title: AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress.
Author: Rasool, R U|Nayak, D|Chakraborty, S|Faheem, M M|Rah, B|Mahajan, P|Gopinath, V|Katoch, A|Iqra, Z|Yousuf, S K|Mukherjee, D|Kumar, L D|Nargotra, A|Goswami, A
PMID: 28530706
Journal: Cell Commun Signal. 2017 Jun 12;15(1):21.
Title: LASP2 suppresses colorectal cancer progression through JNK/p38 MAPK pathway meditated epithelial-mesenchymal transition.
Author: Wang, Bin|Zhang, Lanzhi|Zhao, Liying|Zhou, Rui|Ding, Yanqing|Li, Guoxin|Zhao, Liang
PMID: 28606091
Journal: Int J Oncol. 2017 Aug;51(2):615-624.
Title: 18 beta-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Author: Wang, Saisai|Shen, Yong|Qiu, Runfeng|Chen, Zhiliang|Chen, Zhehang|Chen, Wenbin
PMID: 28656212
Journal: Int J Mol Med. 2017 Sep;40(3):587-606.
Title: Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 28731148
Journal: Am J Physiol Renal Physiol. 2017 Dec 1;313(6):F1223-F1231.
Title: Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease.
Author: Hama, Taketsugu|Nakanishi, Koichi|Sato, Masashi|Mukaiyama, Hironobu|Togawa, Hiroko|Shima, Yuko|Miyajima, Masayasu|Nozu, Kandai|Nagao, Shizuko|Takahashi, Hisahide|Sako, Mayumi|Iijima, Kazumoto|Yoshikawa, Norishige|Suzuki, Hiroyuki
PMID: 28877884
Journal: Oncotarget. 2017 Apr 20;8(35):58587-58600.
Title: Targeting progastrin enhances radiosensitization of colorectal cancer cells.
Author: Kowalski-Chauvel, Aline|Gouaze-Andersson, Valerie|Vignolle-Vidoni, Alix|Delmas, Caroline|Toulas, Christine|Cohen-Jonathan-Moyal, Elizabeth|Seva, Catherine
PMID: 28938581
Journal: Oncotarget. 2017 Apr 24;8(35):58611-58624.
Title: PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways.
Author: Wang, Ping|Zhou, Yi|Mei, Qi|Zhao, Jing|Huang, Liu|Fu, Qiang
PMID: 28938583
Journal: Oncotarget. 2017 Jul 26;8(41):70239-70249.
Title: Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation.
Author: Zhao, Yueliang|Li, Edmund T S|Wang, Mingfu
PMID: 29050275
Journal: BMC Complement Altern Med. 2017 Dec 13;17(1):531.
Title: Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways.
Author: Liu, Haojie|Zhou, Ming
PMID: 29237430
Journal: Cell Physiol Biochem. 2017;44(5):2073-2089.
Title: YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways.
Author: Li, Haijun|He, Fucheng|Zhao, Xin|Zhang, Yuan|Chu, Xi|Hua, Chunlan|Qu, Yunhui|Duan, Yu|Ming, Liang
PMID: 29241219
Journal: Oncol Lett. 2017 Dec;14(6):7947-7956.
Title: Ampelopsin-induced reactive oxygen species enhance the apoptosis of colon cancer cells by activating endoplasmic reticulum stress-mediated AMPK/MAPK/XAF1 signaling.
Author: Park, Ga Bin|Jeong, Jee-Yeong|Kim, Daejin
PMID: 29250183
Journal: Oncotarget. 2017 Aug 10;8(68):112426-112441.
Title: Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells.
Author: Bhardwaj, Monika|Paul, Souren|Jakhar, Rekha|Khan, Imran|Kang, Ji In|Kim, Ho Min|Yun, Jong Won|Lee, Seon-Jin|Cho, Hee Jun|Lee, Hee Gu|Kang, Sun Chul
PMID: 29348836
Journal: Anticancer Agents Med Chem. 2018 Feb 7;17(14):1942-1950.
Title: Thymol Elicits HCT-116 Colorectal Carcinoma Cell Death Through Induction of Oxidative Stress.
Author: Chauhan, Anil Kumar|Bahuguna, Ashutosh|Paul, Souren|Kang, Sun Chul
PMID: 28356011
Journal: Biomol Ther (Seoul). 2018 May 1;26(3):313-321.
Title: Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway.
Author: Lee, Jun Hee|Yun, Chul Won|Lee, Sang Hun
PMID: 28822989
Journal: Clin Cancer Res. 2018 Jan 15;24(2):433-444.
Title: Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.
Author: Bartolome, Ruben A|Aizpurua, Carmen|Jaen, Marta|Torres, Sofia|Calvino, Eva|Imbaud, Juan I|Casal, J Ignacio
PMID: 28916526
Journal: Cell Biol Toxicol. 2018 Aug;34(4):263-277.
Title: Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway.
Author: Li, Qi|Qi, Feng|Meng, Xiangchao|Zhu, Chenpei|Gao, Yingtang
PMID: 29063978
Journal: Anticancer Agents Med Chem. 2018;18(4):583-590.
Title: Oleanolic Acid Inhibits Colorectal Cancer Angiogenesis by Blocking the VEGFR2 Signaling Pathway.
Author: Niu, Guoping|Sun, Li|Pei, Yunfeng|Wang, Duping
PMID: 29065844
Journal: Anticancer Agents Med Chem. 2018;18(3):428-437.
Title: CJK-7, a Novel Flavonoid from Paulownia tomentosa Triggers Cell Death Cascades in HCT-116 Human Colon Carcinoma Cells via Redox Signaling.
Author: Singh, Mahendra Pal|Park, Ki Hun|Khaket, Tejinder Pal|Kang, Sun Chul
PMID: 29076434
Journal: Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):259-272.
Title: RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell.
Author: Lin, Jung-Chun|Lee, Yuan-Chii|Tan, Tse-Hua|Liang, Yu-Chih|Chuang, Huai-Chia|Fann, Yang C|Johnson, Kory R|Lin, Ying-Ju
PMID: 29138007
Journal: Int Immunopharmacol. 2018 Jan;54:296-302.
Title: TNFalpha induces tolerant production of CXC chemokines in colorectal cancer HCT116 cells via A20 inhibition of ERK signaling.
Author: Zhou, Xin|An, Dongjian|Liu, Xueting|Jiang, Manli|Yuan, Chuang|Hu, Jinyue
PMID: 29175508
Journal: Biochem Pharmacol. 2018 Feb;148:64-74.
Title: Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells.
Author: Wu, Qian|Deng, Jianjun|Fan, Daidi|Duan, Zhiguang|Zhu, Chenhui|Fu, Rongzhan|Wang, Shanshan
PMID: 29225132
Journal: Mol Med Rep. 2018 Feb;17(2):3123-3132.
Title: HMGB1 suppresses colon carcinoma cell apoptosis triggered by coculture with dendritic cells via an ER stressassociated autophagy pathway.
Author: Zheng, Yingcheng|Zhu, Guoguo
PMID: 29257231
Journal: Oncol Rep. 2018 Mar;39(3):1387-1395.
Title: Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells.
Author: Zeng, Xianliang|Chen, Sizeng|Lin, Yanfeng|Ke, Zhao
PMID: 29328480
Journal: Mol Med Rep. 2018 Mar;17(3):4203-4212.
Title: Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway.
Author: You, Shuping|Li, Weihong|Guan, Yun
PMID: 29344654
Journal: Anticancer Res. 2018 Feb;38(2):737-743.
Title: Effective Timing of Surgical Resection of Colorectal Cancer Liver Metastases During Chemotherapy.
Author: Osada, Shinji|Gotoh, Ayana|Yokoi, Ryoma|Tsuchiya, Hiroshi|Sakuratani, Takuji|Sasaki, Yoshiyuki|Okumura, Naoki|Hayashi, Hideki|Mukai, Tsuyoshi
PMID: 29374697
Journal: Anticancer Drugs. 2018 Mar;29(3):234-242.
Title: Dioscin inhibits colon cancer cells' growth by reactive oxygen species-mediated mitochondrial dysfunction and p38 and JNK pathways.
Author: Li, Shu|Cheng, Binbin|Hou, Lixin|Huang, Lanwei|Cui, Yongkang|Xu, Duo|Shen, Xiaoping|Li, Shuang
PMID: 29389802
Journal: Sci Rep. 2018 Feb 5;8(1):2334.
Title: p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells.
Author: Zhong, Liang|Huot, Jacques|Simard, Martin J
PMID: 29402939
Journal: Exp Cell Res. 2018 Mar 15;364(2):198-207.
Title: Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling.
Author: Tian, Shaobo|Hu, Jia|Tao, Kaixiong|Wang, Jian|Chu, Yanan|Li, Jing|Liu, Zhibo|Ding, Xueliang|Xu, Luming|Li, Qilin|Cai, Ming|Gao, Jinbo|Shuai, Xiaoming|Wang, Guobin|Wang, Lin|Wang, Zheng
PMID: 29427622
Journal: Saudi J Gastroenterol. 2018 Jan-Feb;24(1):37-45.
Title: The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors.
Author: Przybyla, Tomasz|Wesserling, Martyna|Sakowicz-Burkiewicz, Monika|Maciejewska, Izabela|Pawelczyk, Tadeusz
PMID: 29451183
Journal: Mol Cancer Ther. 2018 May;17(5):943-951.
Title: Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells.
Author: Zhang, Lu|Kim, Sang Bum|Luitel, Krishna|Shay, Jerry W
PMID: 29467273
Journal: Oncol Lett. 2018 Mar;15(3):3820-3827.
Title: TNF-alpha promotes colon cancer cell migration and invasion by upregulating TROP-2.
Author: Zhao, Peng|Zhang, Zhongtao
PMID: 29467899
Journal: Int Immunopharmacol. 2018 Apr;57:82-90.
Title: Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-kappaB and MAPK signalling pathways.
Author: Gao, Zhenfang|Yu, Cuicui|Liang, Haiyue|Wang, Xuekai|Liu, Yue|Li, Xin|Ji, Kai|Xu, Hui|Yang, Mingyan|Liu, Ke|Qi, Dong|Fan, Huaying
PMID: 29475099
Journal: Cell Signal. 2018 Jun;46:92-102.
Title: Targeting of cathepsin C induces autophagic dysregulation that directs ER stress mediated cellular cytotoxicity in colorectal cancer cells.
Author: Khaket, Tejinder Pal|Singh, Mahendra Pal|Khan, Imran|Bhardwaj, Monika|Kang, Sun Chul
PMID: 29501728
Journal: Cell Death Discov. 2018 Feb 8;4:11.
Title: PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer.
Author: Kuriyama, Sei|Tsuji, Tadahiro|Sakuma, Tetsushi|Yamamoto, Takashi|Tanaka, Masamistu
PMID: 29531808
Journal: Oncotarget. 2018 Feb 1;9(15):12304-12315.
Title: MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1.
Author: Liu, Hui|Cheng, Xin-Hua
PMID: 29552311
Journal: Cell Death Dis. 2018 Apr 1;9(4):436.
Title: Nuclear receptor binding protein 1 correlates with better prognosis and induces caspase-dependent intrinsic apoptosis through the JNK signalling pathway in colorectal cancer.
Author: Liao, Yi|Yang, Zihuan|Huang, Jintuan|Chen, Hao|Xiang, Jun|Li, Senmao|Chen, Chunyu|He, Xuan|Lin, Feng|Yang, Zuli|Wang, Jianping
PMID: 29567997
Journal: Cancer Inform. 2018 Mar 26;17:1176935118766522.
Title: The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29636593
Journal: Eur Rev Med Pharmacol Sci. 2018 Apr;22(7):1922-1928.
Title: Peroxiredoxin1 promotes cell proliferation, migration and invasion of colorectal cancer via p38MAPK signaling.
Author: Cong, N|Huang, W|Yuan, J-P|Li, G-Z|Zhai, G-S|Li, B-S
PMID: 29687844
Journal: Int J Mol Med. 2018 Jul;42(1):665-673.
Title: MicroRNA125 inhibits RKO colorectal cancer cell growth by targeting VEGF.
Author: Wu, Qi-Bing|Chen, Jing|Zhu, Jia-Wei|Yin, Xin|You, He-Yang|Lin, Yi-Rong|Zhu, Hua-Qing
PMID: 29693153
Journal: Oncol Lett. 2018 May;15(5):7716-7724.
Title: Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-kappaB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.
Author: Juan, Ta-Kuo|Liu, Kuo-Ching|Kuo, Chao-Lin|Yang, Mei-Due|Chu, Yung-Lin|Yang, Jiun-Long|Wu, Ping-Ping|Huang, Yi-Ping|Lai, Kuang-Chi|Chung, Jing-Gung
PMID: 29731901
Journal: Int J Oncol. 2018 Aug;53(2):750-760.
Title: Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs.
Author: Su, Meng-Qi|Zhou, Yi-Ran|Rao, Xuan|Yang, Hong|Zhuang, Xin-Hao|Ke, Xue-Jia|Peng, Guang-Yong|Zhou, Chang-Lin|Shen, Bai-Yong|Dou, Jie
PMID: 29749481
Journal: Redox Biol. 2018 Jul;17:348-354.
Title: Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells.
Author: Serra, Gessica|Incani, Alessandra|Serreli, Gabriele|Porru, Laura|Melis, M Paola|Tuberoso, Carlo I G|Rossin, Daniela|Biasi, Fiorella|Deiana, Monica
PMID: 29793168
Journal: Biomed Pharmacother. 2018 Aug;104:806-816.
Title: Dioscorea bulbifera induced apoptosis through inhibition of ERK 1/2 and activation of JNK signaling pathways in HCT116 human colorectal carcinoma cells.
Author: Ahmad Hidayat, Ahmad Fadhlurrahman|Chan, Chim Kei|Mohamad, Jamaludin|Abdul Kadir, Habsah
PMID: 29860114
Journal: Med Sci Monit. 2018 Jun 3;24:3710-3719.
Title: Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells.
Author: Meng, Ling-Qi|Wang, Yue|Luo, Ying-Hua|Piao, Xian-Ji|Liu, Chang|Wang, Yue|Zhang, Yi|Wang, Jia-Ru|Wang, Hao|Xu, Wan-Ting|Liu, Yang|Wu, Yi-Qin|Sun, Hu-Nan|Han, Ying-Hao|Jin, Mei-Hua|Shen, Gui-Nan|Fang, Nan-Zhu|Jin, Cheng-Hao
PMID: 29860266
Journal: Cell Physiol Biochem. 2018;47(4):1432-1441.
Title: Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression.
Author: Zhang, Luyao|He, Liang|Zhang, Hua|Chen, Yan
PMID: 29940575
Journal: Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3779-3788.
Title: Study on the function and mechanism of long non-coding RNA DMTF1v4 in the occurrence of colon cancer.
Author: Zhuang, S-T|Cai, Y-J|Gao, H-C|Qiu, J-F|Zeng, L|Zheng, W-J
PMID: 29949153
Journal: Int J Oncol. 2018 Sep;53(3):1313-1322.
Title: Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells in vitro.
Author: Yamaguchi, Masayoshi|Osuka, Satoru|Murata, Tomiyasu
PMID: 29956741
Journal: Br J Cancer. 2018 Jul 10. pii: 10.1038/s41416-018-0174-y.
Title: ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer.
Author: Roseweir, Antonia K|Halcrow, Elaine S|Chichilo, Sergey|Powell, Arfon Gmt|McMillan, Donald C|Horgan, Paul G|Edwards, Joanne
PMID: 29988110
Journal: Neuroreport. 2018 Oct 17;29(15):1249-1255.
Title: High expression of mitogen-activated and stress-activated protein kinase 1 indicates poor prognosis in patients with glioma.
Author: Li, Hailing|Zhao, Changlei|Xu, Min|Yin, Min
PMID: 30020192
Journal: Libyan J Med. 2018 Dec;13(1):1500346.
Title: Roles of the MST1-JNK signaling pathway in apoptosis of colorectal cancer cells induced by Taurine.
Author: Liu, Zhuoqi|Xia, Yanqin|Zhang, Xiali|Liu, Liqiao|Tu, Shuo|Zhu, Weifeng|Yu, Lehan|Wan, Huifang|Yu, Bo|Wan, Fusheng
PMID: 30035680
Journal: Sci Rep. 2018 Aug 7;8(1):11821.
Title: Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1.
Author: Jemaa, Mohamed|Abassi, Yasmin|Kifagi, Chamseddine|Fezai, Myriam|Daams, Renee|Lang, Florian|Massoumi, Ramin
PMID: 30087398
Journal: Expert Rev Gastroenterol Hepatol. 2018 Sep 26:1-18.
Title: An update on dietary consideration in inflammatory bowel disease: anthocyanins and more.
Author: Farzaei, Mohammad Hosein|El-Senduny, Fardous F|Momtaz, Saeideh|Parvizi, Fatemeh|Iranpanah, Amin|Tewari, Devesh|Naseri, Rozita|Abdolghaffari, Amir Hossein|Rezaei, Nima
PMID: 30136591
Journal: Cell Death Dis. 2018 Aug 29;9(9):877.
Title: Novel beta-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer.
Author: Kim, Su Jin|Noh, Tae Hwan|Son, Sujin|Kim, Do Hyun|Kim, Wooseong|Lee, Yunna|Choo, Jieun|Heo, Gwangbeom|Kim, Min Jae|Chung, Hae Young|Jung, Yunjin|Jung, Jee Hyung|Moon, Hyung Ryong|Im, Eunok
PMID: 30158525
Journal: Biosci Biotechnol Biochem. 2018 Sep 10:1-10.
Title: Methyl-beta-cyclodextrin potentiates the BITC-induced anti-cancer effect through modulation of the Akt phosphorylation in human colorectal cancer cells.
Author: Yang, Qifu|Miyagawa, Miku|Liu, Xiaoyang|Zhu, Beiwei|Munemasa, Shintaro|Nakamura, Toshiyuki|Murata, Yoshiyuki|Nakamura, Yoshimasa
PMID: 30200817
Journal: Cell Biol Int. 2018 Sep 11.
Title: Quercetin preferentially induces apoptosis in KRAS-mutant colorectal cancer cells via JNK signaling pathways.
Author: Yang, Yiwen|Wang, Tao|Chen, Degao|Ma, Qizhao|Zheng, Yanjiang|Liao, Shiping|Wang, Yufang|Zhang, Ji
PMID: 30203888
Journal: Biochem Biophys Res Commun. 2018 Sep 12. pii: S0006-291X(18)31972-7.
Title: MicroRNA-613 promotes colon cancer cell proliferation, invasion and migration by targeting ATOH1.
Author: Yang, Xuanxuan|Zhang, Luo|Song, Xing|He, Wenting|Zhang, Dachuan|Lu, Qicheng|Wu, Jun|Wu, Changping|Jiang, Jingting
PMID: 30219232
Journal: BMC Cell Biol. 2018 Sep 25;19(1):21.
Title: Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways.
Author: Jieensinue, Sayilaxi|Zhu, Hong|Li, Guangcheng|Dong, Keli|Liang, Meiting|Li, Yayue
PMID: 30253740
Journal: J Sci Food Agric. 2018 Oct 24.
Title: Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells.
Author: Shin, Min-Kyoung|Jeon, Yong-Deok|Jin, Jong-Sik
PMID: 30357838
Journal: Pharmaceutics. 2018 Oct 23;10(4). pii: pharmaceutics10040198.
Title: An Intrinsic Mitochondrial Pathway Is Required for Phytic Acid-Chitosan-Iron Oxide Nanocomposite (Phy-CS-MNP) to Induce G(0)/G(1) Cell Cycle Arrest and Apoptosis in the Human Colorectal Cancer (HT-29) Cell Line.
Author: Tan, Bee Ling|Norhaizan, Mohd Esa|Chan, Lee Chin
PMID: 30360519
Journal: Biomed Pharmacother. 2018 Oct 1;108:1208-1215.
Title: Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway.
Author: Gao, Guang-Yi|Ma, Jun|Lu, Peng|Jiang, Xuan|Chang, Cheng
PMID: 30372822