Primary Site >> Stomach Cancer

Gene >> MAPK3

Journal: J Biol Chem. 1997 Oct 24;272(43):27015-24.
Title: Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells.
Author: Hocker, M|Henihan, R J|Rosewicz, S|Riecken, E O|Zhang, Z|Koh, T J|Wang, T C
PMID: 9341140
Journal: Gut. 2001 Jul;49(1):18-22.
Title: Helicobacter pylori induced transactivation of SRE and AP-1 through the ERK signalling pathway in gastric cancer cells.
Author: Mitsuno, Y|Yoshida, H|Maeda, S|Ogura, K|Hirata, Y|Kawabe, T|Shiratori, Y|Omata, M
PMID: 11413105
Journal: Biochem Pharmacol. 2001 Nov 15;62(10):1423-32.
Title: Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism.
Author: Atten, M J|Attar, B M|Milson, T|Holian, O
PMID: 11709203
Journal: Arch Pathol Lab Med. 2002 Sep;126(9):1096-100.
Title: ras Gene mutations and expression of Ras signal transduction mediators in gastric adenocarcinomas.
Author: Yoo, Jinyoung|Park, Sonya Y|Robinson, Robert A|Kang, Seok Jin|Ahn, Woong Shick|Kang, Chang Suk
PMID: 12204060
Journal: FEBS Lett. 2002 Oct 23;530(1-3):59-64.
Title: Reg protein is overexpressed in gastric cancer cells, where it activates a signal transduction pathway that converges on ERK1/2 to stimulate growth.
Author: Kadowaki, Yasunori|Ishihara, Shunji|Miyaoka, Youichi|Rumi, Mohammed Azharul Karim|Sato, Hiroshi|Kazumori, Hideaki|Adachi, Kyoichi|Takasawa, Shin|Okamoto, Hiroshi|Chiba, Tsutomu|Kinoshita, Yoshikazu
PMID: 12387866
Journal: Ai Zheng. 2002 Aug;21(8):850-4.
Title: [Inhibition of activator protein-1 on the growth of gastric cancer by octreotide].
Author: Wang, Chun-hui|Tang, Cheng-wei
PMID: 12478891
Journal: Mol Cells. 2002 Dec 31;14(3):348-54.
Title: MAPK signaling is involved in camptothecin-induced cell death.
Author: Lee, Seongeun|Lee, Ho-Soon|Baek, Myungin|Lee, Dae-Yeon|Bang, Yung-Jue|Cho, Hae-Nyun|Lee, Yun-Sil|Ha, Ji-Hong|Kim, Hae-Yeong|Jeoung, Doo-Il
PMID: 12521296
Journal: J Biol Chem. 2003 Mar 7;278(10):8190-8. Epub 2002 Dec 30.
Title: Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements.
Author: Schafer, Georgia|Cramer, Thorsten|Suske, Guntram|Kemmner, Wolfgang|Wiedenmann, Bertram|Hocker, Michael
PMID: 12509426
Journal: Infect Immun. 2003 Feb;71(2):830-7.
Title: Effect of inhibition of extracellular signal-regulated kinase 1 and 2 pathway on apoptosis and bcl-2 expression in Helicobacter pylori-infected AGS cells.
Author: Choi, Il Ju|Kim, Joo Sung|Kim, Jung Mogg|Jung, Hyun Chae|Song, In Sung
PMID: 12540563
Journal: Br J Cancer. 2003 Mar 10;88(5):796-802.
Title: Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells.
Author: Akagi, M|Kawaguchi, M|Liu, W|McCarty, M F|Takeda, A|Fan, F|Stoeltzing, O|Parikh, A A|Jung, Y D|Bucana, C D|Mansfield, P F|Hicklin, D J|Ellis, L M
PMID: 12618892
Journal: Oncol Rep. 2003 Sep-Oct;10(5):1467-71.
Title: P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells.
Author: Shin, Boo A|Yoo, Hyeon G|Kim, Hong S|Kim, Mi H|Hwang, Young S|Chay, Kee O|Lee, Kee Y|Ahn, Bong W|Jung, Young D
PMID: 12883725
Journal: Cancer Res. 2003 Aug 1;63(15):4648-55.
Title: Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system.
Author: Lee, Dong Hoon|Yang, Young|Lee, Soon Jung|Kim, Kun-Yong|Koo, Tae Hyeon|Shin, Sun Mi|Song, Kyu Sang|Lee, Young Ho|Kim, Yung-Jin|Lee, Jung Joon|Choi, Inpyo|Lee, Jeong-Hyung
PMID: 12907645
Journal: Cell Microbiol. 2003 Nov;5(11):821-34.
Title: Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors.
Author: Juttner, Stefan|Cramer, Thorsten|Wessler, Silja|Walduck, Anna|Gao, Feng|Schmitz, Frank|Wunder, Christian|Weber, Matthias|Fischer, Susan M|Schmidt, Wolfgang E|Wiedenmann, Bertram|Meyer, Thomas F|Naumann, Michael|Hocker, Michael
PMID: 14531897
Journal: Mol Cancer. 2003 Sep 23;2:33.
Title: TGFbeta1 activates c-Jun and Erk1 via alphaVbeta6 integrin.
Author: Luettich, Karsta|Schmidt, Christian
PMID: 14572313
Journal: Wei Sheng Yan Jiu. 2003 Nov;32(6):573-5.
Title: [Roles of ERK1/2 MAPK in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells].
Author: Zhao, Yan|Wu, Kun|Yu, Yinghui|Li, Guichang
PMID: 14963907
Journal: Biochem J. 2004 Apr 1;379(Pt 1):141-50.
Title: TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal-regulated kinases) cascade activity dependent on c-Src activity.
Author: Kim, Hwang-Phill|Lee, Mi-Sook|Yu, Jiyon|Park, Jin-Ah|Jong, Hyun-Soon|Kim, Tae-You|Lee, Jung Weon|Bang, Yung-Jue
PMID: 14720123
Journal: Int J Oncol. 2004 May;24(5):1229-34.
Title: Smad2 mediates Erk1/2 activation by TGF-beta1 in suspended, but not in adherent, gastric carcinoma cells.
Author: Lee, Mi-Sook|Ko, Seong-Gyu|Kim, Hwang-Phill|Kim, Yong-Bae|Lee, Sung-Yul|Kim, Sang-Gyun|Jong, Hyun-Soon|Kim, Tae-You|Lee, Jung Weon|Bang, Yung-Jue
PMID: 15067346
Journal: Oncogene. 2004 Aug 26;23(39):6603-11.
Title: Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells.
Author: Hwang, Young S|Jeong, Min|Park, Jung S|Kim, Mi H|Lee, Dae B|Shin, Boo A|Mukaida, Naofumi|Ellis, Lee M|Kim, Hyeong R|Ahn, Bong W|Jung, Young D
PMID: 15208668
Journal: Biochem Biophys Res Commun. 2004 Jul 30;320(3):816-24.
Title: Blockage of HSP 90 modulates Helicobacter pylori-induced IL-8 productions through the inactivation of transcriptional factors of AP-1 and NF-kappaB.
Author: Yeo, Marie|Park, Hyun-kyung|Lee, Ki-myung|Lee, Kwang Jae|Kim, Jin Hong|Cho, Sung Won|Hahm, Ki-baik
PMID: 15240121
Journal: World J Gastroenterol. 2005 Feb 7;11(5):623-8.
Title: Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer.
Author: Liang, Bin|Wang, Shan|Zhu, Xue-Guang|Yu, Yong-Xiang|Cui, Zhi-Rong|Yu, You-Zhi
PMID: 15655810
Journal: Cancer Sci. 2005 Mar;96(3):170-5.
Title: Helicobacter pylori-dependent NF-kappa B activation in newly established Mongolian gerbil gastric cancer cell lines.
Author: Nozaki, Koji|Tanaka, Harunari|Ikehara, Yuzuru|Cao, Xueyuan|Nakanishi, Hayao|Azuma, Takeshi|Yamazaki, Shiho|Yamaoka, Yoshio|Shimizu, Nobuyuki|Mafune, Ken-ichi|Kaminishi, Michio|Tatematsu, Masae
PMID: 15771620
Journal: Oncogene. 2005 Jun 2;24(24):3886-95.
Title: Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Du, Qin|Xu, Weizhen
PMID: 15856031
Journal: Int J Oncol. 2005 Jun;26(6):1669-74.
Title: Extracellular signal-regulated kinase and AP-1 pathways are involved in reactive oxygen species-induced urokinase plasminogen activator receptor expression in human gastric cancer cells.
Author: Kim, Mi H|Cho, Hyung S|Jung, Min|Hong, Min H|Lee, Sam K|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 15870884
Journal: Cancer Res. 2005 Oct 15;65(20):9159-63.
Title: Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
Author: Shida, Dai|Kitayama, Joji|Mori, Ken|Watanabe, Toshiaki|Nagawa, Hirokazu
PMID: 16230373
Journal: J Environ Pathol Toxicol Oncol. 2005;24(4):261-9.
Title: Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human gastric cancer (AGS) cells.
Author: Kim, Min-Jung|Kim, Do-Hee|Na, Hye-Kyung|Oh, Tae Young|Shin, Chang-Yell|Surh Ph D Professor, Young-Joon
PMID: 16393120
Journal: Biochem Biophys Res Commun. 2006 Mar 31;342(1):179-83.
Title: Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3.
Author: Peng, Lirong|Jin, Genglin|Wang, Li|Guo, Jianpin|Meng, Lin|Shou, Chengchao
PMID: 16472776
Journal: Dig Liver Dis. 2006 May;38(5):310-8. Epub 2006 Mar 9.
Title: Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells.
Author: Liu, S-Q|Yu, J-P|Yu, H-G|Lv, P|Chen, H-l
PMID: 16527552
Journal: J Gastrointest Surg. 2006 Apr;10(4):551-62.
Title: Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells.
Author: Abdel-Latif, Mohamed M M|Windle, Henry|Terres, Ana|Eidhin, Deirdre Ni|Kelleher, Dermot|Reynolds, John V
PMID: 16627221
Journal: Cell Mol Biol Lett. 2006;11(3):408-23.
Title: Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803.
Author: Ling, Hui|Zhang, Liang-Yun|Su, Qi|Song, Ying|Luo, Zhao-Yang|Zhou, Xiu Tian|Zeng, Xi|He, Jie|Tan, Hui|Yuan, Jing-Ping
PMID: 16874458
Journal: FASEB J. 2006 Sep;20(11):1886-8. Epub 2006 Jul 28.
Title: Cellular prion protein promotes invasion and metastasis of gastric cancer.
Author: Pan, Yanglin|Zhao, Lina|Liang, Jie|Liu, Jie|Shi, Yongquan|Liu, Na|Zhang, Guoyun|Jin, Haifeng|Gao, Juan|Xie, Huahong|Wang, Jun|Liu, Zhiguo|Fan, Daiming
PMID: 16877520
Journal: Cancer Sci. 2006 Oct;97(10):1037-43. Epub 2006 Aug 17.
Title: Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha.
Author: Wada, Yoshiyuki|Yoshida, Kazuhiro|Hihara, Jun|Konishi, Kazuo|Tanabe, Kazuaki|Ukon, Kei|Taomoto, Junnya|Suzuki, Takahisa|Mizuiri, Hirozumi
PMID: 16918998
Journal: Br J Cancer. 2006 Dec 4;95(11):1504-13. Epub 2006 Nov 7.
Title: Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis.
Author: Yokoyama, H|Ikehara, Y|Kodera, Y|Ikehara, S|Yatabe, Y|Mochizuki, Y|Koike, M|Fujiwara, M|Nakao, A|Tatematsu, M|Nakanishi, H
PMID: 17088902
Journal: Cancer Lett. 2007 Mar 18;247(2):345-52. Epub 2006 Jul 12.
Title: alpha-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner.
Author: Zhao, Yan|Zhao, Xiujuan|Yang, Baofeng|Neuzil, Jiri|Wu, Kun
PMID: 16839662
Journal: Oncogene. 2007 Mar 1;26(10):1468-76.
Title: Interleukin-18 is a critical factor for vascular endothelial growth factor-enhanced migration in human gastric cancer cell lines.
Author: Kim, K-E|Song, H|Kim, T S|Yoon, D|Kim, C-w|Bang, S I|Hur, D Y|Park, H|Cho, D-H
PMID: 17001321
Journal: Toxicol Sci. 2007 Mar;96(1):21-9. Epub 2006 Sep 26.
Title: Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells.
Author: Shin, Vivian Yvonne|Wu, William Ka Kei|Chu, Kent Man|Koo, Marcel Wing Leung|Wong, Helen Pui Shan|Lam, Emily Kai Yee|Tai, Emily Kin Ki|Cho, Chi Hin
PMID: 17003101
Journal: Biochem Biophys Res Commun. 2007 Mar 2;354(1):154-9. Epub 2006 Dec 29.
Title: Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells.
Author: Yasuda, Hiroshi|Hirata, Shuko|Inoue, Kazuaki|Mashima, Hirosato|Ohnishi, Hirohide|Yoshiba, Makoto
PMID: 17214962
Journal: Mol Cancer Ther. 2007 Mar;6(3):1123-32.
Title: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Author: Lang, Sven A|Klein, Dagmar|Moser, Christian|Gaumann, Andreas|Glockzin, Gabriel|Dahlke, Marc H|Dietmaier, Wolfgang|Bolder, Ulrich|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17363505
Journal: Cancer Biol Ther. 2007 May;6(5):769-74. Epub 2007 Feb 12.
Title: Hypoxia induced overexpression of PrP(C) in gastric cancer cell lines.
Author: Liang, Jie|Bai, Feihu|Luo, Guanhong|Wang, Jingbo|Liu, Jingmei|Ge, Fulin|Pan, Yanglin|Yao, Liping|Du, Rui|Li, Xiaohua|Fan, Rui|Zhang, Hongbo|Guo, Xuegang|Wu, Kaichun|Fan, Daiming
PMID: 17387271
Journal: Mol Cell Biochem. 2007 Sep;303(1-2):151-60.
Title: Involvement of MGr1-Ag/37LRP in the vincristine-induced HIF-1 expression in gastric cancer cells.
Author: Liu, Lili|Ning, Xiaoxuan|Sun, Li|Shi, Yongquan|Han, Shuang|Guo, Changcun|Chen, Yu|Sun, Shiren|Yin, Fang|Wu, Kaichun|Fan, Daiming
PMID: 17476462
Journal: J Pathol. 2007 Oct;213(2):140-51.
Title: Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression.
Author: Jackson, C B|Judd, L M|Menheniott, T R|Kronborg, I|Dow, C|Yeomans, N D|Boussioutas, A|Robb, L|Giraud, A S
PMID: 17724739
Journal: Planta Med. 2007 Sep;73(11):1176-81. Epub 2007 Sep 7.
Title: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells.
Author: Jiang, Tiejun|Zhu, Yongliang|Luo, Cong|Lu, Xiaoyong|Zhang, Wo|Qiu, Fuming|Huang, Jian
PMID: 17823871
Journal: Anticancer Res. 2007 Sep-Oct;27(5A):3411-7.
Title: Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells.
Author: Chang, Hee J|Kim, Mi H|Baek, Min K|Park, Jung S|Chung, Ik J|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 17970088
Journal: Mol Cancer Res. 2007 Nov;5(11):1111-23.
Title: Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2.
Author: Lin, Been-Ren|Chang, Cheng-Chi|Chen, Li-Ro|Wu, Ming-Hsun|Wang, Ming-Yang|Kuo, I-Hsin|Chu, Chia-Yu|Chang, King-Jen|Lee, Po-Huang|Chen, Wei-Jao|Kuo, Min-Liang|Lin, Ming-Tsan
PMID: 18025257
Journal: Growth Factors. 2007 Dec;25(6):373-81.
Title: Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin.
Author: Pazos, Yolanda|Alvarez, Carlos J P|Camina, Jesus P|Casanueva, Felipe F
PMID: 18365868
Journal: Dig Dis Sci. 2008 Jan;53(1):181-7. Epub 2007 May 24.
Title: 12-lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway.
Author: Chen, Feng-Lin|Wang, Xiao-Zhong|Li, Jian-Ying|Yu, Jie-Ping|Huang, Cai-Yun|Chen, Zhi-Xin
PMID: 17522976
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G263-75.
Title: Fas Ag-FasL coupling leads to ERK1/2-mediated proliferation of gastric mucosal cells.
Author: Li, Hanchen|Cai, Xun|Fan, Xueli|Moquin, Brian|Stoicov, Calin|Houghton, Jeanmarie
PMID: 17991709
Journal: Br J Nutr. 2008 Jun;99(6):1247-54. Epub 2007 Dec 17.
Title: Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling.
Author: Sun, Wenguang|Wang, Qi|Chen, Bingqing|Liu, Jiaren|Liu, Huikun|Xu, Weili
PMID: 18081943
Journal: Cancer Sci. 2008 Jan;99(1):185.
Title: Blockage of intracellular proton extrusion with proton extrusions with proton pump inhibitor induces apoptosis in gastric cancer.
Author: Yeo, Marie|Kim, Dong-Kyu|Park, Hee Jin|Cho, Sung Won|Cheong, Jae Youn|Lee, Kwang Jae
PMID: 18224727
Journal: Carcinogenesis. 2008 Apr;29(4):704-12.
Title: Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.
Author: Kim, Kwang-Kyu|Lee, Jung Joon|Yang, Young|You, Kwan-Hee|Lee, Jeong-Hyung
PMID: 18258606
Journal: Invest New Drugs. 2008 Dec;26(6):517-24.
Title: CPT21, a novel compound with anti-proliferative effect against gastric cancer cell SGC7901.
Author: Zhang, Bo|Luo, Yu|Weng, Qinjie|He, Qiaojun|Lu, Wei|Yang, Bo
PMID: 18283417
Journal: J Biol Chem. 2008 Jun 6;283(23):15807-15.
Title: Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.
Author: Lin, Ming-Tsan|Kuo, I-Hsin|Chang, Cheng-Chi|Chu, Chia-Yu|Chen, Hsing-Yu|Lin, Been-Ren|Sureshbabu, Munisamy|Shih, Hou-Jung|Kuo, Min-Liang
PMID: 18381294
Journal: Food Chem Toxicol. 2008 Aug;46(8):2653-7.
Title: The effect of polysaccharide extracted from the marine alga Capsosiphon fulvescens on ethanol administration.
Author: Hwang, Hye-Jeong|Kwon, Mi-Jin|Kim, In-Hye|Nam, Taek-Jeong
PMID: 18524446
Journal: Biochem Biophys Res Commun. 2008 Aug 22;373(2):330-4.
Title: Constitutive hypophosphorylation of extracellular signal-regulated kinases-1/2 and down-regulation of c-Jun in human gastric adenocarcinoma.
Author: Wu, William Ka Kei|Sung, Joseph Joe Yiu|Yu, Le|Li, Zhi Jie|Chu, Kent Man|Cho, Chi Hin
PMID: 18570890
Journal: Oncol Rep. 2008 Dec;20(6):1569-75.
Title: EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells.
Author: Baek, Min K|Kim, Mi H|Jang, Hee J|Park, Jung S|Chung, Ik J|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 19020743
Journal: Drug News Perspect. 2008 Oct;21(8):417-23.
Title: Role of TMPRSS4 during cancer progression.
Author: Choi, So-Young|Shin, Hyun-Chul|Kim, Seon-Young|Park, Young Woo
PMID: 19034347
Journal: Cancer Lett. 2009 Feb 8;274(1):40-6.
Title: Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells.
Author: Zhang, Lin Jie|Chen, Si|Wu, Pin|Hu, Chun Song|Thorne, Rick F|Luo, Chang Ming|Hersey, Peter|Zhang, Xu Dong
PMID: 18829155
Journal: J Gastroenterol Hepatol. 2009 Apr;24(4):688-96.
Title: Proliferative effects of gamma-aminobutyric acid on the gastric cancer cell line are associated with extracellular signal-regulated kinase 1/2 activation.
Author: Maemura, Kentaro|Shiraishi, Nanako|Sakagami, Kumiko|Kawakami, Ken|Inoue, Takuya|Murano, Mitsuyuki|Watanabe, Masahito|Otsuki, Yoshinori
PMID: 19032445
Journal: Mol Carcinog. 2009 Aug;48(8):703-12.
Title: Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer.
Author: Seto, Motoko|Ohta, Miki|Asaoka, Yoshinari|Ikenoue, Tsuneo|Tada, Motohisa|Miyabayashi, Koji|Mohri, Dai|Tanaka, Yasuo|Ijichi, Hideaki|Tateishi, Keisuke|Kanai, Fumihiko|Kawabe, Takao|Omata, Masao
PMID: 19142899
Journal: Int J Oncol. 2009 Feb;34(2):473-80.
Title: Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer.
Author: Lee, Hyo Jin|Kim, Seong Woo|Kim, Ha Yon|Li, Shengjin|Yun, Hwan Jung|Song, Kyu Sang|Kim, Samyong|Jo, Deog Yeon
PMID: 19148483
Journal: Cancer Lett. 2009 Jul 8;279(2):137-44.
Title: Midkine positively regulates the proliferation of human gastric cancer cells.
Author: Xu, Yingying|Qu, Xiujuan|Zhang, Xue|Luo, Yang|Zhang, Ye|Luo, Ying|Hou, Kezuo|Liu, Yunpeng
PMID: 19250738
Journal: Int J Oncol. 2009 Jun;34(6):1573-82.
Title: Local angiotensin II-generation in human gastric cancer: correlation with tumor progression through the activation of ERK1/2, NF-kappaB and survivin.
Author: Kinoshita, Jun|Fushida, Sachio|Harada, Shinichi|Yagi, Yasumichi|Fujita, Hideto|Kinami, Shinichi|Ninomiya, Itasu|Fujimura, Takashi|Kayahara, Masato|Yashiro, Masakazu|Hirakawa, Kosei|Ohta, Tetsuo
PMID: 19424575
Journal: Food Chem Toxicol. 2009 Aug;47(8):2013-21.
Title: Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells.
Author: Lu, Te-Ling|Huang, Guan-Jhong|Lu, Te-Jung|Wu, Jin-Bin|Wu, Chieh-Hsi|Yang, Tung-Chuan|Iizuka, Akira|Chen, Yuh-Fung
PMID: 19477214
Journal: Int J Cancer. 2010 Jun 1;126(11):2716-25.
Title: Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells.
Author: Shigematsu, Hideo|Yoshida, Kazuhiro|Sanada, Yuichi|Osada, Shinnji|Takahashi, Takao|Wada, Yoshiyuki|Konishi, Kazuo|Okada, Morihito|Fukushima, Masakazu
PMID: 19856312
Journal: J Biol Chem. 2010 May 21;285(21):16042-50.
Title: Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells.
Author: Lee, In Ohk|Kim, Jie Hyun|Choi, Yeun Jung|Pillinger, Michael H|Kim, Seok-Yong|Blaser, Martin J|Lee, Yong Chan
PMID: 20348091
Journal: Oncol Rep. 2010 Jun;23(6):1735-45.
Title: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines.
Author: Luo, Hui-Yan|Wei, Wei|Shi, Yan-Xia|Chen, Xiao-Qin|Li, Yu-Hong|Wang, Feng|Qiu, Miao-Zhen|Li, Fang-Hua|Yan, Shu-Li|Zeng, Mu-Sheng|Huang, Peng|Xu, Rui-Hua
PMID: 20428833
Journal: Toxicology. 2010 Jul-Aug;274(1-3):27-33.
Title: gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line.
Author: Bi, Sheng|Liu, Jia-Ren|Li, Yang|Wang, Qi|Liu, Hui-Kun|Yan, Ya-Geng|Chen, Bing-Qing|Sun, Wen-Guang
PMID: 20452389
Journal: Biosci Biotechnol Biochem. 2010;74(5):1018-24. Epub 2010 May 7.
Title: Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells.
Author: Sekiguchi, Hirotaka|Irie, Kazuhiro|Murakami, Akira
PMID: 20460732
Journal: Anticancer Res. 2010 Jun;30(6):2135-43.
Title: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways.
Author: Yang, Mei-Due|Lai, Kuang-Chi|Lai, Tung-Yuan|Hsu, Shu-Chun|Kuo, Chao-Lin|Yu, Chun-Shu|Lin, Meng-Liang|Yang, Jai-Sing|Kuo, Hsiu-Maan|Wu, Shin-Hwar|Chung, Jing-Gung
PMID: 20651362
Journal: FEBS Lett. 2010 Sep 24;584(18):4077-82.
Title: Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.
Author: Ramachandran, Subramaniam|Shida, Dai|Nagahashi, Masayuki|Fang, Xianjun|Milstien, Sheldon|Takabe, Kazuaki|Spiegel, Sarah
PMID: 20804754
Journal: Cancer Res. 2010 Oct 15;70(20):7981-91.
Title: Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters.
Author: Mi, Yan-Jun|Liang, Yong-Ju|Huang, Hong-Bing|Zhao, Hong-Yun|Wu, Chung-Pu|Wang, Fang|Tao, Li-Yang|Zhang, Chuan-Zhao|Dai, Chun-Ling|Tiwari, Amit K|Ma, Xiao-Xu|To, Kenneth Kin Wah|Ambudkar, Suresh V|Chen, Zhe-Sheng|Fu, Li-Wu
PMID: 20876799
Journal: Mol Cancer Res. 2010 Nov;8(11):1477-88.
Title: CADPE inhibits PMA-stimulated gastric carcinoma cell invasion and matrix metalloproteinase-9 expression by FAK/MEK/ERK-mediated AP-1 activation.
Author: Han, Honghui|Du, Bing|Pan, Xinhua|Liu, Junchen|Zhao, Qufei|Lian, Xiaoyuan|Qian, Min|Liu, Mingyao
PMID: 21047770
Journal: BMC Gastroenterol. 2010 Nov 10;10:132.
Title: Mycoplasma hyorhinis infection in gastric carcinoma and its effects on the malignant phenotypes of gastric cancer cells.
Author: Yang, Hua|Qu, Like|Ma, Huachong|Chen, Ling|Liu, Wenbin|Liu, Caiyun|Meng, Lin|Wu, Jian|Shou, Chengchao
PMID: 21062494
Journal: Hum Exp Toxicol. 2011 Apr;30(4):296-306.
Title: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.
Author: Ho, Chin-Chin|Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Ma, Chia-Yu|Lin, Meng-Liang|Yang, Jai-Sing|Chung, Jing-Gung
PMID: 20498032
Journal: J Cell Physiol. 2011 Mar;226(3):762-8.
Title: Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells.
Author: Eguchi, Ryoji|Fujimori, Yoshihiro|Takeda, Hiromi|Tabata, Chiharu|Ohta, Toshiro|Kuribayashi, Kouzo|Fukuoka, Kazuya|Nakano, Takashi
PMID: 20799280
Journal: Carcinogenesis. 2011 Feb;32(2):175-81.
Title: MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-kappaB signals in gastric cancer cells.
Author: Park, Jung Sun|Park, Ji Hye|Khoi, Pham Ngoc|Joo, Young Eun|Jung, Young Do
PMID: 21081472
Journal: J Cell Biochem. 2011 Apr;112(4):1192-205.
Title: Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells.
Author: Park, Jae Myung|Xian, Xiang-Shu|Choi, Myung-Gyu|Park, Hyeyeon|Cho, Yu Kyung|Lee, In Seok|Kim, Sang Woo|Chung, In-Sik
PMID: 21312237
Journal: Cancer Invest. 2011 May;29(4):257-65.
Title: 15-hydroxyprostaglandin dehydrogenase is downregulated and exhibits tumor suppressor activity in gastric cancer.
Author: Song, Ho June|Myung, Seung-Jae|Kim, In-Wha|Jeong, Jin-Yong|Park, Young Soo|Lee, Sun Mi|Nam, Won Hee|Ryu, Yeon-Mi|Fink, Stephen P|Yang, Dong-Hoon|Jung, Hwoon-Yong|Kim, Jin-Ho
PMID: 21469975
Journal: Gastric Cancer. 2011 Oct;14(4):322-31.
Title: Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells.
Author: Zhou, Jianjiang|Xie, Yuan|Zhao, Yan|Wang, Shu|Li, Yu
PMID: 21509655
Journal: J Biomed Sci. 2011 Jun 14;18:39.
Title: Stanniocalcin-1 promotes tumor angiogenesis through up-regulation of VEGF in gastric cancer cells.
Author: He, Ling-fang|Wang, Ting-ting|Gao, Qian-ying|Zhao, Guang-feng|Huang, Ya-hong|Yu, Li-ke|Hou, Ya-yi
PMID: 21672207
Journal: Cancer Biol Ther. 2011 Sep 15;12(6):494-502.
Title: Interferon-alpha sensitizes human gastric cancer cells to TRAIL-induced apoptosis via activation of the c-CBL-dependent MAPK/ERK pathway.
Author: Qu, Jinglei|Zhao, Mingfang|Teng, Yuee|Zhang, Ye|Hou, Kezuo|Jiang, Youhong|Yang, Xianghong|Shang, Hong|Qu, Xiujuan|Liu, Yunpeng
PMID: 21725207
Journal: Proteomics. 2011 Sep;11(18):3657-64.
Title: Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells.
Author: Yan, Guang-Rong|Xu, Song-Hui|Tan, Zi-Lu|Yin, Xin-Feng|He, Qing-Yu
PMID: 21751384
Journal: Int J Oncol. 2011 Dec;39(6):1529-36.
Title: Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.
Author: Nakata, Wachiko|Hayakawa, Yoku|Nakagawa, Hayato|Sakamoto, Kei|Kinoshita, Hiroto|Takahashi, Ryota|Hirata, Yoshihiro|Maeda, Shin|Koike, Kazuhiko
PMID: 21785822
Journal: Int J Cancer. 2012 Feb 15;130(4):787-97.
Title: Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer.
Author: Xu, Jianbo|Zhang, Changhua|He, Yulong|Wu, Hui|Wang, Zhao|Song, Wu|Li, Wen|He, Weiling|Cai, Shirong|Zhan, Wenhua
PMID: 21387301
Journal: Med Oncol. 2012 Jun;29(2):948-56.
Title: PTP1B expression contributes to gastric cancer progression.
Author: Wang, Jinguo|Liu, Bingya|Chen, Xuehua|Su, Liping|Wu, Pei|Wu, Jian|Zhu, Zhenggang
PMID: 21442314
Journal: Cancer Lett. 2012 Apr 1;317(1):24-32.
Title: LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells.
Author: Zhang, Jian|Wang, Jian|Guo, Qiqiang|Wang, Yu|Zhou, Ying|Peng, Huizhi|Cheng, Maosheng|Zhao, Dongmei|Li, Feng
PMID: 22085492
Journal: Mol Cancer Ther. 2012 Feb;11(2):439-51.
Title: Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.
Author: Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22135232
Journal: Food Chem Toxicol. 2012 Mar;50(3-4):684-8.
Title: Galangin induces apoptosis in gastric cancer cells via regulation of ubiquitin carboxy-terminal hydrolase isozyme L1 and glutathione S-transferase P.
Author: Kim, Deuk Ae|Jeon, Young Keul|Nam, Myeong Jin
PMID: 22142694
Journal: Mol Nutr Food Res. 2012 Feb;56(2):325-35.
Title: Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion.
Author: Rubach, Malte|Lang, Roman|Seebach, Elisabeth|Somoza, Mark M|Hofmann, Thomas|Somoza, Veronika
PMID: 22147653
Journal: Gut. 2012 Dec;61(12):1678-85.
Title: Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells.
Author: Nam, Ki Taek|O'Neal, Ryan L|Coffey, Robert J|Finke, Paul E|Barker, Nick|Goldenring, James R
PMID: 22198711
Journal: Toxicol Lett. 2012 Apr 5;210(1):78-86.
Title: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells.
Author: Hu, Chen|Zou, Mei-Juan|Zhao, Li|Lu, Na|Sun, Ya-Jing|Gou, Shao-Hua|Xi, Tao|Guo, Qing-Long
PMID: 22322152
Journal: Food Chem Toxicol. 2012 Dec;50(12):4333-9.
Title: Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis.
Author: Lin, Ming-Wei|Lin, An-Shen|Wu, Deng-Chyang|Wang, Sophie S W|Chang, Fang-Rong|Wu, Yang-Chang|Huang, Yaw-Bin
PMID: 22634261
Journal: BMC Immunol. 2012 Jun 6;13:28.
Title: Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer.
Author: Yang, Donghai|Fan, Xin|Yin, Ping|Wen, Qiang|Yan, Feng|Yuan, Sibo|Liu, Bin|Zhuang, Guohong|Liu, Zhongchen
PMID: 22672288
Journal: Cancer. 2012 Dec 1;118(23):5757-67.
Title: Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.
Author: Cheng, Tsu-Yao|Wu, Ming-Shiang|Lin, Jaw-Town|Lin, Ming-Tsan|Shun, Chia-Tung|Huang, Hsin-Yi|Hua, Kuo-Tai|Kuo, Min-Liang
PMID: 22736399
Journal: Life Sci. 2012 Sep 4;91(5-6):186-93.
Title: ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-kappaB-dependent and Notch-independent mechanism.
Author: Yao, Jun|Qian, Cui-Juan|Ye, Bei|Zhang, Xin|Liang, Yong
PMID: 22781708
Journal: BMC Cancer. 2012 Jul 16;12:290.
Title: ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI(3)K and MAPK signaling pathways in gastric cancer.
Author: Zhong, Jing|Chen, Shujie|Xue, Meng|Du, Qin|Cai, Jianting|Jin, Hongchuan|Si, Jianmin|Wang, Liangjing
PMID: 22799764
Journal: Oncol Rep. 2012 Oct;28(4):1429-34.
Title: Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells.
Author: Lim, Sung-Chul|Duong, Hong-Quan|Parajuli, Keshab Raj|Han, Song Iy
PMID: 22824956
Journal: J Dig Dis. 2012 Sep;13(9):453-8.
Title: The proliferative effects of ghrelin on human gastric cancer AGS cells.
Author: Tian, Pei Ying|Fan, Xiao Ming
PMID: 22908970
Journal: Yao Xue Xue Bao. 2012 Jun;47(6):816-21.
Title: [Mechanisms of (2-methyl-n-butyl) shikonin induced apoptosis of gastric cancer SGC-7901 cells].
Author: Wang, Hai-Bing|Ma, Xiao-Qiong
PMID: 22919733
Journal: Oncol Rep. 2012 Nov;28(5):1917-23.
Title: Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells.
Author: Zhang, Cheng|Gao, Guang-Rong|Lv, Chen-Guang|Zhang, Boa-Lei|Zhang, Zhi-Li|Zhang, Xue-Feng
PMID: 22941376
Journal: Am J Pathol. 2012 Oct;181(4):1316-26.
Title: Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients.
Author: Chang, Emily Yun-Chia|Tsai, Shu-Huei|Shun, Chia-Tung|Hee, Siow-Wey|Chang, Yi-Cheng|Tsai, Yun-Chih|Tsai, Jaw-Shiun|Chen, Hsian-Ju|Chou, Jia-Wei|Lin, Shih-Yao|Chuang, Lee-Ming
PMID: 22998775
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2012 Nov;28(11):1142-5.
Title: [Mig-7 enhances vasculogenic mimicry in gastric cancer cells].
Author: Li, Wen-li|Gao, Qing
PMID: 23127401
Journal: Oncogene. 2013 Feb 28;32(9):1183-92.
Title: Fas signaling promotes motility and metastasis through epithelial-mesenchymal transition in gastrointestinal cancer.
Author: Zheng, H X|Cai, Y D|Wang, Y D|Cui, X B|Xie, T T|Li, W J|Peng, L|Zhang, Y|Wang, Z Q|Wang, J|Jiang, B
PMID: 22508480
Journal: J Basic Microbiol. 2013 Feb;53(2):147-55.
Title: Proliferative and apoptotic effects of gastric epithelial cells induced by coccoid Helicobacter pylori.
Author: Li, Neng|Han, Lei|Chen, Jiansen|Lin, Xu|Chen, Hao|She, Feifei
PMID: 22581720
Journal: Pathol Oncol Res. 2013 Jan;19(1):11-8.
Title: Semaphorin 5A, an axon guidance molecule, enhances the invasion and metastasis of human gastric cancer through activation of MMP9.
Author: Pan, Guoqing|Zhang, Xiangling|Ren, Junyu|Lu, Jianbo|Li, Wenliang|Fu, Hongmei|Zhang, Shufang|Li, Jun
PMID: 22821546
Journal: Mol Cell Biochem. 2013 Jan;372(1-2):1-8.
Title: CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway.
Author: Zhong, Jialing|Zhao, Mei|Luo, Qing|Ma, Yiming|Liu, Jian|Wang, Jia|Yang, Mei|Yuan, Xinghua|Sang, Jianli|Huang, Changzhi
PMID: 23070808
Journal: Hepatogastroenterology. 2013 Jun;60(124):943-8.
Title: Tumor-suppressive effects of 1, 25-dihydroxyvitamin D3 in gastric cancer cells.
Author: Bao, Anyu|Li, Yan|Tong, Yongqing|Zheng, Hongyun|Wu, Wei|Wei, Chuandong
PMID: 23298900
Journal: Carcinogenesis. 2013 May;34(5):974-83.
Title: Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.
Author: Dong, Zhaogang|Xu, Xiaofei|Du, Lutao|Yang, Yongmei|Cheng, Huanhuan|Zhang, Xin|Li, Zewu|Wang, Lili|Li, Juan|Liu, Hui|Qu, Xun|Wang, Chuanxin
PMID: 23354307
Journal: Am J Pathol. 2013 Apr;182(4):1275-85.
Title: Down-regulation of dual-specificity phosphatase 5 in gastric cancer by promoter CpG island hypermethylation and its potential role in carcinogenesis.
Author: Shin, So-Hyun|Park, Seog-Yun|Kang, Gyeong Hoon
PMID: 23402999
Journal: Oncol Lett. 2013 Feb;5(2):574-582.
Title: Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Author: Wang, Jun Pu|Hu, Wan Ming|Wang, Kuan Song|Yu, Jun|Luo, Bai Hua|Wu, Chang|Chen, Zhi Hong|Luo, Geng Qiu|Liu, Yu Wu|Liu, Qin Lai|Xiao, Yan|Zhou, Hai Yan|Yang, Xiao Jing|Jiang, Hai Ying|Li, Jing He|Wen, Ji Fang
PMID: 23420470
Journal: Mol Med Rep. 2013 Jun;7(6):1805-11.
Title: RNAimediated knockdown of PRL3 inhibits cell invasion and downregulates ERK 1/2 expression in the human gastric cancer cell line, SGC7901.
Author: Cao, Yi|Tu, Yi|Mei, Jinhong|Li, Zhengrong|Jie, Zhigang|Xu, Shan|Xu, Linlin|Wang, Shanshan|Xiong, Yifeng
PMID: 23589069
Journal: PLoS One. 2013 Apr 23;8(4):e60369.
Title: MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.
Author: Lei, Huizi|Zou, Dongling|Li, Zheng|Luo, Min|Dong, Lei|Wang, Bin|Yin, Haixin|Ma, Yanni|Liu, Changzheng|Wang, Fang|Zhang, Junwu|Yu, Jia|Li, Yu
PMID: 23637748
Journal: J Biochem Mol Toxicol. 2013 Jul;27(7):364-9.
Title: Periostin mediates the increased pro-angiogenic activity of gastric cancer cells under hypoxic conditions.
Author: Qiu, Feng|Shi, Chun-hua|Zheng, Jun|Liu, Yu-bin
PMID: 23728938
Journal: Cancer Biol Ther. 2013 Sep;14(9):833-9.
Title: Combination treatment of PD98059 and DAPT in gastric cancer through induction of apoptosis and downregulation of WNT/beta-catenin.
Author: Yao, Jun|Qian, Cuijuan|Shu, Ting|Zhang, Xin|Zhao, Zhiqiang|Liang, Yong
PMID: 23792588
Journal: Carcinogenesis. 2013 Dec;34(12):2861-9.
Title: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
Author: Wu, Jinhua|Xie, Na|Xie, Ke|Zeng, Jun|Cheng, Lin|Lei, Yunlong|Liu, Yuan|Song, Linhong|Dong, Dandan|Chen, Yi|Zeng, Rui|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23803691
Journal: Exp Biol Med (Maywood). 2013 Aug 1;238(8):903-12.
Title: ERK1/2 signalling pathway is involved in CD147-mediated gastric cancer cell line SGC7901 proliferation and invasion.
Author: Chen, Liping|Pan, Yuqin|Gu, Ling|Nie, Zhenlin|He, Bangshun|Song, Guoqi|Li, Rui|Xu, Yeqiong|Gao, Tianyi|Wang, Shukui
PMID: 23828593
Journal: PLoS One. 2013 Jun 28;8(6):e67542.
Title: Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells.
Author: Wang, Le-Yi|Liu, Yun-Peng|Chen, Li-Gang|Chen, Yan-Ling|Tan, Li|Liu, Jing-Jing|Jazag, Amarsanaa|Ren, Jian-Lin|Guleng, Bayasi
PMID: 23840737
Journal: Oncology. 2013;85(2):78-85.
Title: Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer.
Author: Kim, Jong Gwang|Lee, Soo Jung|Chae, Yee Soo|Kang, Byung Woog|Lee, You Jin|Oh, Sung Yong|Kim, Min Chan|Kim, Ki Han|Kim, Su-Jin
PMID: 23860205
Journal: Oncol Rep. 2013 Oct;30(4):1681-6.
Title: Anticancer effects of AcPheLysPABCdoxorubicin via mitochondriacentered apoptosis involving reactive oxidative stress and the ERK1/2 signaling pathway in MGC803 cells.
Author: Zhong, Yan-Jun|Liu, Shao-Ping|Firestone, Raymond A|Hong, Ya-Ping|Li, Yan
PMID: 23877402
Journal: PLoS One. 2013 Jul 29;8(7):e70311.
Title: The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
Author: Luo, Zu-Yan|Wang, Yuan-Yu|Zhao, Zhong-Sheng|Li, Bo|Chen, Jun-Fa
PMID: 23922976
Journal: Oncol Res. 2013;20(9):393-402.
Title: Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells.
Author: Lee, Kyung Hee|Koh, Sung Ae|Kim, Jae-Ryong
PMID: 23924923
Journal: Oncol Rep. 2013 Nov;30(5):2520-8.
Title: Expression and prognostic significance of Livin in gastric cancer.
Author: Chung, Cho-Yun|Park, Young-Lan|Kim, Nuri|Park, Hyung-Chul|Park, Hyun-Bum|Myung, Dae-Seong|Kim, Jong-Sun|Cho, Sung-Bum|Lee, Wan-Sik|Joo, Young-Eun
PMID: 24008725
Journal: Life Sci. 2013 Nov 19;93(22):830-9.
Title: Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine.
Author: Shi, Hai-Lian|Wu, Xiao-Jun|Liu, Yan|Xie, Jian-Qun
PMID: 24063987
Journal: Evid Based Complement Alternat Med. 2013;2013:518301.
Title: Potential Therapeutic Role of Hispidulin in Gastric Cancer through Induction of Apoptosis via NAG-1 Signaling.
Author: Yu, Chao Yuan|Su, Kang-Yi|Lee, Po-Lei|Jhan, Jie-Yu|Tsao, Po-Hung|Chan, De-Chuan|Chen, Yi-Lin Sophia
PMID: 24159347
Journal: Acta Pharmacol Sin. 2013 Dec;34(12):1535-44.
Title: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway.
Author: Wang, Hai-jun|Liu, Yu|Fan, Li-qiao|Han, Cai-li|Jiang, Ye|Cheng, Shu-jie|Li, Yong
PMID: 24241351
Journal: Asian Pac J Cancer Prev. 2013;14(11):6261-5.
Title: Hypermethylation and clinicopathological significance of RASAL1 gene in gastric cancer.
Author: Chen, Hong|Pan, Ying|Cheng, Zheng-Yuan|Wang, Zhi|Liu, Yang|Zhao, Zhu-Jiang|Fan, Hong
PMID: 24377515
Journal: Oncogene. 2014 Feb 6;33(6):783-93.
Title: MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1.
Author: Li, T|Lu, Y Y|Zhao, X D|Guo, H Q|Liu, C H|Li, H|Zhou, L|Han, Y N|Wu, K C|Nie, Y Z|Shi, Y Q|Fan, D M
PMID: 23353818
Journal: Cancer Sci. 2014 Jan;105(1):26-34.
Title: CMTM3 inhibits cell migration and invasion and correlates with favorable prognosis in gastric cancer.
Author: Su, Yu|Lin, Yi|Zhang, Lianhai|Liu, Baocai|Yuan, Wanqiong|Mo, Xiaoning|Wang, Xiaohong|Li, Henan|Xing, Xiaofang|Cheng, Xiaojing|Dong, Bin|Hu, Ying|Du, Hong|Zhu, Yubing|Ding, Ning|Li, Jiyou|Liu, Weili|Ma, Yongzhen|Qiu, Xiaoyan|Ji, Jiafu|Han, Wenling
PMID: 24131472
Journal: Mol Cell Biochem. 2014 Feb;387(1-2):159-70.
Title: ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells.
Author: Qian, Cuijuan|Yao, Jun|Wang, Jiji|Wang, Lan|Xue, Meng|Zhou, Tianhua|Liu, Weili|Si, Jianmin
PMID: 24178240
Journal: Peptides. 2014 Jan;51:131-8.
Title: Increased serum chemerin level promotes cellular invasiveness in gastric cancer: a clinical and experimental study.
Author: Wang, Chunhu|Wu, William K K|Liu, Xiaodong|To, Kai-Fa|Chen, Gong G|Yu, Jun|Ng, Enders K W
PMID: 24274970
Journal: Neoplasma. 2014;61(2):136-43.
Title: Inhibition of MEK sensitizes gastric cancer cells to TRAIL-induced apoptosis.
Author: Wu, P|Cheng, Y W|Wang, J Y|Zhang, X D|Zhang, L J
PMID: 24299309
Journal: Mol Med Rep. 2014 Feb;9(2):499-502.
Title: Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells.
Author: Park, Seon-Young|Kim, Ji-Young|Lee, Su-Mi|Jun, Chung-Hwan|Cho, Sung-Bum|Park, Chang-Hwan|Joo, Young-Eun|Kim, Hyun-Soo|Choi, Sung-Kyu|Rew, Jong-Sun
PMID: 24337453
Journal: Int J Mol Med. 2014 Mar;33(3):589-96.
Title: Overexpression of GNAO1 correlates with poor prognosis in patients with gastric cancer and plays a role in gastric cancer cell proliferation and apoptosis.
Author: Liu, Zhen|Zhang, Jun|Wu, Lijun|Liu, Jie|Zhang, Mingqing
PMID: 24366063
Journal: Int J Oncol. 2014 Mar;44(3):805-11.
Title: Cholesterol induces autophagic and apoptotic death in gastric carcinoma cells.
Author: Lim, Sung-Chul|Parajuli, Keshab Raj|Duong, Hong-Quan|Choi, Jeong Eun|Han, Song Iy
PMID: 24399152
Journal: Hum Cell. 2014 Jul;27(3):103-10.
Title: RASAL1 influences the proliferation and invasion of gastric cancer cells by regulating the RAS/ERK signaling pathway.
Author: Chen, Hong|Cheng, Zheng-Yuan|Pan, Ying|Wang, Zhi|Liu, Yang|Zhang, Jin-Qi
PMID: 24531877
Journal: Biochem Biophys Res Commun. 2014 Apr 18;446(4):822-9.
Title: The role of leptin in gastric cancer: clinicopathologic features and molecular mechanisms.
Author: Lee, Kang Nyeong|Choi, Ho Soon|Yang, Sun Young|Park, Hyun Ki|Lee, Young Yiul|Lee, Oh Young|Yoon, Byung Chul|Hahm, Joon Soo|Paik, Seung Sam
PMID: 24569072
Journal: Oncol Rep. 2014 May;31(5):2312-20.
Title: SPARC expression is negatively correlated with clinicopathological factors of gastric cancer and inhibits malignancy of gastric cancer cells.
Author: Zhang, Junling|Wang, Pengyuan|Zhu, Jing|Wang, Wei|Yin, Jie|Zhang, Chi|Chen, Ziyi|Sun, Lie|Wan, Yuanlian|Wang, Xin|Chen, Guowei|Liu, Yucun
PMID: 24676680
Journal: PLoS One. 2014 Apr 15;9(4):e94422.
Title: MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression.
Author: Peng, Yang|Liu, Yan-Min|Li, Lu-Chun|Wang, Lu-Lu|Wu, Xiao-Ling
PMID: 24736504
Journal: Cell Death Dis. 2014 Jun 19;5:e1295.
Title: The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression.
Author: Zhu, Q|Zhang, X|Zhang, L|Li, W|Wu, H|Yuan, X|Mao, F|Wang, M|Zhu, W|Qian, H|Xu, W
PMID: 24946088
Journal: Biochim Biophys Acta. 2014 Sep;1839(9):785-92.
Title: CDX2 can be regulated through the signalling pathways activated by IL-6 in gastric cells.
Author: Cobler, Lara|Pera, Manuel|Garrido, Marta|Iglesias, Mar|de Bolos, Carme
PMID: 24953186
Journal: Cytokine. 2014 Sep;69(1):6-13.
Title: Association of CXCR1 and 2 expressions with gastric cancer metastasis in ex vivo and tumor cell invasion in vitro.
Author: Li, Zhen|Wang, Ying|Dong, Suiwei|Ge, Chunlei|Xiao, Yanbin|Li, Ruilei|Ma, Xiang|Xue, Yuanbo|Zhang, Qi|Lv, Juan|Tan, Qinghua|Zhu, Zhitao|Song, Xin|Tan, Jing
PMID: 25022956
Journal: Int J Oncol. 2014 Oct;45(4):1760-8.
Title: Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-kappaB, and AP-1 signaling pathways.
Author: Khoi, Pham Ngoc|Xia, Yong|Lian, Sen|Kim, Ho Dong|Kim, Do Hyun|Joo, Young Eun|Chay, Kee-Oh|Kim, Kyung Keun|Jung, Young Do
PMID: 25069788
Journal: Tumour Biol. 2014 Nov;35(11):10891-6.
Title: Inhibition of epidermal growth factor receptor signaling prohibits metastasis of gastric cancer via downregulation of MMP7 and MMP13.
Author: Ye, Yinghai|Zhou, Xiaocong|Li, Xiaoyang|Tang, Yinhe|Sun, Yusheng|Fang, Jun
PMID: 25085584
Journal: Front Microbiol. 2014 Jul 18;5:356.
Title: Analysis of T4SS-induced signaling by H. pylori using quantitative phosphoproteomics.
Author: Glowinski, Frithjof|Holland, Carsten|Thiede, Bernd|Jungblut, Peter R|Meyer, Thomas F
PMID: 25101063
Journal: Neoplasma. 2014;61(6):627-37.
Title: Annexin A2 is implicated in multi-drug-resistance in gastric cancer through p38MAPK and AKT pathway.
Author: Zhang, Z D|Li, Y|Fan, Q|Zhao, B|Tan, B|Zhao, X F
PMID: 25150310
Journal: Oncol Lett. 2014 Oct;8(4):1739-1744.
Title: Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines.
Author: Gu, Mengli|Zhang, Yan|Zhou, Xinxin|Ma, Han|Yao, Hangping|Ji, Feng
PMID: 25202402
Journal: Mol Cancer Ther. 2014 Dec;13(12):3098-106.
Title: MEK inhibitor for gastric cancer with MEK1 gene mutations.
Author: Sogabe, Shunsuke|Togashi, Yosuke|Kato, Hiroaki|Kogita, Akihiro|Mizukami, Takuro|Sakamoto, Yoichi|Banno, Eri|Terashima, Masato|Hayashi, Hidetoshi|de Velasco, Marco A|Sakai, Kazuko|Fujita, Yoshihiko|Tomida, Shuta|Yasuda, Takushi|Takeyama, Yoshifumi|Okuno, K
PMID: 25253779
Journal: Hum Pathol. 2014 Dec;45(12):2488-96.
Title: GNAS mutation as an alternative mechanism of activation of the Wnt/beta-catenin signaling pathway in gastric adenocarcinoma of the fundic gland type.
Author: Nomura, Ryosuke|Saito, Tsuyoshi|Mitomi, Hiroyuki|Hidaka, Yasuhiro|Lee, Se-yong|Watanabe, Sumio|Yao, Takashi
PMID: 25288233
Journal: Cell Commun Signal. 2014 Nov 15;12:69.
Title: An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2.
Author: Tseng, Po-Chun|Chen, Chia-Ling|Shan, Yan-Shen|Chang, Wen-Teng|Liu, Hsiao-Sheng|Hong, Tse-Ming|Hsieh, Chia-Yuan|Lin, Sheng-Hsiang|Lin, Chiou-Feng
PMID: 25398317
Journal: Oncotarget. 2014 Dec 15;5(23):11873-85.
Title: Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A.
Author: Chen, Hongxia|Li, Lingmin|Wang, Shaojun|Lei, Yupeng|Ge, Qi|Lv, Nonghua|Zhou, Xiaodong|Chen, Changyan
PMID: 25428912
Journal: Environ Toxicol. 2015 Feb;30(2):129-36.
Title: Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells.
Author: Chan, Chien-Pin|Tsai, Yao-Ting|Chen, Yao-Li|Hsu, Yu-Wen|Tseng, Joseph T|Chuang, Hung-Yi|Shiurba, Robert|Lee, Mei-Hsien|Wang, Jaw-Yuan|Chang, Wei-Chiao
PMID: 23765435
Journal: Tumour Biol. 2015 Apr;36(4):2457-64.
Title: The human epididymis protein 4 acts as a prognostic factor and promotes progression of gastric cancer.
Author: Guo, Yun-Di|Wang, Jing-Hao|Lu, Huan|Li, Xiao-Ning|Song, Wei-Wei|Zhang, Xiao-Dan|Zhang, Wen-Ming
PMID: 25432133
Journal: J Cancer Res Clin Oncol. 2015 Jun;141(6):1037-47.
Title: NAIF1 inhibits gastric cancer cells migration and invasion via the MAPK pathways.
Author: Yang, Mei|Gu, Yu-Yu|Peng, Hua|Zhao, Mei|Wang, Jia|Huang, Sheng-Kai|Yuan, Xing-Hua|Li, Jia|Sang, Jian-Li|Luo, Qing|Huang, Changzhi
PMID: 25432142
Journal: Tumour Biol. 2015 Apr;36(4):2517-22.
Title: 1-butyltryptophan inhibits cell proliferation, migration, and invasion through the Akt pathway in human gastric cancer cells.
Author: Sun, Ting|Tian, Hua|Xin, YangXun
PMID: 25433499
Journal: Int J Mol Med. 2015 Feb;35(2):539-45.
Title: Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC-7901 gastric cancer cells through the ERK signaling pathway.
Author: Liu, Yuanyuan|Zhao, Yuyan|Ju, Shujing|Guo, Lei
PMID: 25515760
Journal: Anticancer Drugs. 2015 Apr;26(4):379-87.
Title: The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer.
Author: Xu, Chaochao|Li, Wulan|Qiu, Peihong|Xia, Yiqun|Du, Xiaojing|Wang, Fen|Shen, Lailai|Chen, Qiuxiang|Zhao, Yunjie|Jin, Rong|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 25521558
Journal: Cancer Chemother Pharmacol. 2015 Feb;75(2):353-63.
Title: Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.
Author: Guo, Bingyu|Zhang, Tingting|Su, Jingyuan|Wang, Kaiwen|Li, Xiaoming
PMID: 25527205
Journal: Biochim Biophys Acta. 2015 May;1852(5):970-9.
Title: miR218-5p regulates the proliferation of gastric cancer cells by targeting TFF1 in an Erk1/2-dependent manner.
Author: Shi, Ying|Chen, Guo-Bin|Huang, Qing-Wen|Chen, Xu|Liu, Jing-Jing|Xu, Wei|Huang, Xiao-Xiao|Liu, Yun-Peng|Xiao, Chuan-Xing|Wu, Deng-Chyang|Guleng, Bayasi|Ren, Jian-Lin
PMID: 25652124
Journal: Oncol Rep. 2015 Apr;33(4):1630-8.
Title: Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2.
Author: Zhang, Qiu-Yu|Wu, Lin-Qing|Zhang, Tao|Han, Yan-Fei|Lin, Xu
PMID: 25652880
Journal: Dig Dis Sci. 2015 May;60(5):1265-72.
Title: IL-33 Promotes Gastric Cancer Cell Invasion and Migration Via ST2-ERK1/2 Pathway.
Author: Yu, Xi-Xiang|Hu, Zhe|Shen, Xian|Dong, Li-Yang|Zhou, Wei-Zhong|Hu, Wen-Hao
PMID: 25655003
Journal: Med Oncol. 2015 Mar;32(3):76.
Title: C23 protein meditates bone morphogenetic protein-2-mediated EMT via up-regulation of Erk1/2 and Akt in gastric cancer.
Author: Yang, Yonggang|Yang, Chunyan|Zhang, Jianping
PMID: 25698539
Journal: Biochem Biophys Res Commun. 2015 Apr 10;459(3):379-86.
Title: Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway.
Author: Yang, Yoolhee|Cheon, Soyoung|Jung, Min Kyung|Song, Seok Bean|Kim, Daejin|Kim, Hee Jung|Park, Hyunjeong|Bang, Sa Ik|Cho, Daeho
PMID: 25727011
Journal: Asian Pac J Cancer Prev. 2015;16(3):1077-82.
Title: RASAL1 attenuates gastric carcinogenesis in nude mice by blocking RAS/ERK signaling.
Author: Chen, Hong|Zhao, Ji-Yi|Qian, Xu-Chen|Cheng, Zheng-Yuan|Liu, Yang|Wang, Zhi
PMID: 25735335
Journal: World J Gastroenterol. 2015 Feb 28;21(8):2323-35.
Title: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation.
Author: Cheng, Ya-Jun|Zhu, Zhen-Xin|Zhou, Jian-Sheng|Hu, Zun-Qi|Zhang, Jian-Peng|Cai, Qing-Ping|Wang, Liang-Hua
PMID: 25741138
Journal: PLoS One. 2015 Apr 15;10(4):e0124007.
Title: Chrysin inhibits tumor promoter-induced MMP-9 expression by blocking AP-1 via suppression of ERK and JNK pathways in gastric cancer cells.
Author: Xia, Yong|Lian, Sen|Khoi, Pham Ngoc|Yoon, Hyun Joong|Joo, Young Eun|Chay, Kee Oh|Kim, Kyung Keun|Do Jung, Young
PMID: 25875631
Journal: Tumour Biol. 2015 Sep;36(9):7233-41.
Title: A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer.
Author: Fan, Lei|Li, Wulan|Ying, Shilong|Shi, Lingyi|Wang, Zhe|Chen, Gaozhi|Ye, Hui|Wu, Xiaoping|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 25894376
Journal: Med Oncol. 2015 May;32(5):162.
Title: Endothelial cell protein C receptor promotes MGC803 gastric cancer cells proliferation and migration by activating ERK1/2.
Author: Wang, Qingling|Liu, Qingru|Wang, Tianyuan|Yang, Hongli|Han, Zhengjie|Zhang, Peng
PMID: 25895599
Journal: Oncol Rep. 2015 Jun;33(6):2871-82.
Title: Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells.
Author: Liu, Shi-Quan|Xu, Chun-Yan|Qin, Meng-Bin|Tan, Lin|Zhuge, Chun-Feng|Mao, Ye-Bo|Lai, Ming-Yu|Huang, Jie-An
PMID: 25962735
Journal: J Exp Clin Cancer Res. 2015 May 20;34:52.
Title: Gastric cancer-derived mesenchymal stem cells prompt gastric cancer progression through secretion of interleukin-8.
Author: Li, Wei|Zhou, Ying|Yang, Jin|Zhang, Xu|Zhang, Huanhuan|Zhang, Ting|Zhao, Shaolin|Zheng, Ping|Huo, Juan|Wu, Huiyi
PMID: 25986392
Journal: Dig Dis Sci. 2015 Sep;60(9):2700-11.
Title: Cyclophilin A Enhances Cell Proliferation and Xenografted Tumor Growth of Early Gastric Cancer.
Author: Feng, Wenhua|Xin, Yan|Xiao, Yuping|Li, Wenhui|Sun, Dan
PMID: 26008617
Journal: Tumour Biol. 2015 Nov;36(11):8379-87.
Title: The de-ubiquitinase UCHL1 promotes gastric cancer metastasis via the Akt and Erk1/2 pathways.
Author: Gu, Yu-yu|Yang, Mei|Zhao, Mei|Luo, Qing|Yang, Lin|Peng, Hua|Wang, Jia|Huang, Sheng-kai|Zheng, Zhao-xu|Yuan, Xing-hua|Liu, Ping|Huang, Chang-zhi
PMID: 26018507
Journal: Oncotarget. 2015 Aug 21;6(24):20449-65.
Title: Epigenetically downregulated Semaphorin 3E contributes to gastric cancer.
Author: Chen, Hui|Xie, Guo-Hua|Wang, Wei-Wei|Yuan, Xiang-Liang|Xing, Wen-Ming|Liu, Hong-Jing|Chen, Jin|Dou, Min|Shen, Li-Song
PMID: 26036259
Journal: Cytokine. 2015 Dec;76(2):163-169.
Title: CrkL meditates CCL20/CCR6-induced EMT in gastric cancer.
Author: Han, Gang|Wu, Dawei|Yang, Yongan|Li, Zhiyun|Zhang, Jiapin|Li, Chengjun
PMID: 26044596
Journal: Oncol Rep. 2015 Aug;34(2):1011-6.
Title: Myeloid cell leukemia-1 promotes epithelial-mesenchymal transition of human gastric cancer cells.
Author: Lee, Wan-Sik|Kim, Nuri|Park, Young-Ran|Oh, Hyung-Hoon|Myung, Eun|Kim, Seung-Hun|Yu, Hyung-Min|Kim, Mi-Young|Oak, Chan-Young|Chung, Cho-Yun|Park, Hyung-Chul|Myung, Dae-Seong|Cho, Sung-Bum|Joo, Young-Eun
PMID: 26058661
Journal: Phytother Res. 2015 Oct;29(10):1665-71.
Title: Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke-induced Gastric Epithelial-Mesenchymal Transition in Mice.
Author: Liang, Zhaofeng|Wu, Rui|Xie, Wei|Geng, Hao|Zhao, Li|Xie, Chunfeng|Wu, Jieshu|Geng, Shanshan|Li, Xiaoting|Zhu, Mingming|Zhu, Weiwei|Zhu, Jianyun|Huang, Cong|Ma, Xiao|Zhong, Caiyun|Han, Hongyu
PMID: 26074474
Journal: Int J Oncol. 2015 Aug;47(2):499-505.
Title: EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition.
Author: Mizukami, Takuro|Togashi, Yosuke|Sogabe, Shunsuke|Banno, Eri|Terashima, Masato|De Velasco, Marco A|Sakai, Kazuko|Fujita, Yoshihiko|Tomida, Shuta|Nakajima, Takako Eguchi|Boku, Narikazu|Nishio, Kazuto
PMID: 26081723
Journal: Int Immunopharmacol. 2015 Dec;29(2):808-817.
Title: The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-kappaB.
Author: Gnanaprakasam, J N Rashida|Estrada-Muniz, Elizabet|Vega, Libia
PMID: 26371858
Journal: World J Gastroenterol. 2015 Sep 14;21(34):9945-56.
Title: beta-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation.
Author: Liu, Jun-Song|Che, Xiang-Ming|Chang, Shuai|Qiu, Guang-Lin|He, Shi-Cai|Fan, Lin|Zhao, Wei|Zhang, Zheng-Liang|Wang, Shu-Feng
PMID: 26379399
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Aug;35(9):1234-8.
Title: [Effects of beta-elemene on proliferation and apoptosis of SGC7901 gastric cancer cells in vitro and the underlying mechanisms].
Author: Liu, Junsong|Liu, Xianglong|Qiu, Guanglin|Zhang, Zhengliang|Fan, Lin|Zhao, Wei|He, Shicai|Chang, Shuai|Che, Xiangming
PMID: 26403730
Journal: Mol Med Rep. 2015 Nov;12(5):7335-43.
Title: Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines.
Author: Zhao, Yuan-Yuan|Yu, Li|Liu, Bao-Ling|He, Xin-Jia|Zhang, Bi-Yuan
PMID: 26459009
Journal: Gastric Cancer. 2016 Jan;19(1):74-84.
Title: Interleukin-1B signalling leads to increased survival of gastric carcinoma cells through a CREB-C/EBPbeta-associated mechanism.
Author: Resende, Carlos|Regalo, Goncalo|Duraes, Cecilia|Pinto, Marta Teixeira|Wen, Xiaogang|Figueiredo, Ceu|Carneiro, Fatima|Machado, Jose C
PMID: 25740226
Journal: Tumour Biol. 2016 Jan;37(1):641-51.
Title: CCL18 promotes the invasion and migration of gastric cancer cells via ERK1/2/NF-kappaB signaling pathway.
Author: Hou, Xu|Zhang, Ying|Qiao, Haiquan
PMID: 26242263
Journal: Br J Pharmacol. 2016 Jan;173(2):357-71.
Title: All-trans retinoic acid protects against doxorubicin-induced cardiotoxicity by activating the ERK2 signalling pathway.
Author: Yang, Liang|Luo, Cheng|Chen, Cong|Wang, Xun|Shi, Wen|Liu, Jiankang
PMID: 26507774
Journal: Anticancer Drugs. 2016 Mar;27(3):164-72.
Title: Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage.
Author: Li, Wulan|Du, Xiaojing|Chen, Qiuxiang|Kang, Yanting|Xu, Chaochao|Fan, Lei|Ye, Hui|Ying, Shilong|Shi, Lingyi|Jin, Rong|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 26556626
Journal: Gen Physiol Biophys. 2016 Jan;35(1):25-34.
Title: Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation.
Author: Mondal, Arindam|Biswas, Raktim|Rhee, Yun-Hee|Kim, Jongkee|Ahn, Jin-Chul
PMID: 26612919
Journal: Eur J Cancer Prev. 2016 Nov;25(6):490-9.
Title: Sustained ERK activation-mediated proliferation inhibition of farrerol on human gastric carcinoma cell line by G0/G1-phase cell-cycle arrest.
Author: Liu, Enli|Li, Jie|Shi, Shasha|Wang, Xiaojian|Liang, Taigang|Wu, Bowei|Li, Qingshan
PMID: 26656929
Journal: Oncotarget. 2016 Jan 26;7(4):4454-67.
Title: Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib.
Author: Hui, Kwai Fung|Yeung, Po Ling|Chiang, Alan K S
PMID: 26683357
Journal: Oncotarget. 2016 Feb 9;7(6):7066-79.
Title: Tissue transglutaminase-2 promotes gastric cancer progression via the ERK1/2 pathway.
Author: Wang, Xiaofeng|Yu, Zhenjia|Zhou, Quan|Wu, Xiongyan|Chen, Xuehua|Li, Jianfang|Zhu, Zhenggang|Liu, Bingya|Su, Liping
PMID: 26771235
Journal: J Infect Dis. 2016 Jun 1;213(11):1767-76.
Title: Helicobacter pylori Activates Matrix Metalloproteinase 10 in Gastric Epithelial Cells via EGFR and ERK-mediated Pathways.
Author: Costa, Angela M|Ferreira, Rui M|Pinto-Ribeiro, Ines|Sougleri, Ioanna S|Oliveira, Maria J|Carreto, Laura|Santos, Manuel A|Sgouras, Dionyssios N|Carneiro, Fatima|Leite, Marina|Figueiredo, Ceu
PMID: 26802142
Journal: BMC Cancer. 2016 Feb 4;16:60.
Title: Differences in TGF-beta1 signaling and clinicopathologic characteristics of histologic subtypes of gastric cancer.
Author: Pak, Kyung Ho|Kim, Dong Hoon|Kim, Hyunki|Lee, Do Hyung|Cheong, Jae-Ho
PMID: 26846663
Journal: Oncotarget. 2016 Apr 19;7(16):21601-17.
Title: APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.
Author: Hong, Se-Hoon|Lee, Won Jae|Kim, Young Doo|Kim, Hyunjoo|Jeon, Young-Jun|Lim, Bitna|Cho, Dong-Hyung|Heo, Won Do|Yang, Doo-Hyun|Kim, Chan-Young|Yang, Han-Kwang|Yang, Jin Kuk|Jung, Yong-Keun
PMID: 26942872
Journal: J Cell Mol Med. 2016 May;20(5):962-72.
Title: Suppression of IL-8-Src signalling axis by 17beta-estradiol inhibits human mesenchymal stem cells-mediated gastric cancer invasion.
Author: Liu, Chung-Jung|Kuo, Fu-Chen|Wang, Chiu-Lin|Kuo, Chao-Hung|Wang, Sophie S W|Chen, Chiao-Yun|Huang, Yaw-Bin|Cheng, Kuang-Hung|Yokoyama, Kazunari K|Chen, Chun-Lin|Lu, Chien-Yu|Wu, Deng-Chyang
PMID: 26945908
Journal: Int J Oncol. 2016 May;48(5):2184-96.
Title: CXCR1 promotes malignant behavior of gastric cancer cells in vitro and in vivo in AKT and ERK1/2 phosphorylation.
Author: Wang, Junpu|Hu, Wanming|Wu, Xiaoying|Wang, Kuansong|Yu, Jun|Luo, Baihua|Luo, Gengqiu|Wang, Weiyuan|Wang, Huiling|Li, Jinghe|Wen, Jifang
PMID: 26983663
Journal: Cancer Gene Ther. 2016 Apr;23(4):98-106.
Title: Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Author: Zhu, Y|Tao, M|Wu, J|Meng, Y|Xu, C|Tian, Y|Zhou, X|Xiang, J|Zhang, H|Xie, Y
PMID: 26987289
Journal: Oncol Lett. 2016 Mar;11(3):1835-1840.
Title: Expression of tumor necrosis factor-alpha-induced protein 8 in stage III gastric cancer and the correlation with DcR3 and ERK1/2.
Author: Hu, Ruyi|Liu, Wenming|Qiu, Xingfeng|Lin, Zhenghe|Xie, Yan|Hong, Xingya|Paerhati, Reyila|Qi, Zhongquan|Zhuang, Guohong|Liu, Zhongchen
PMID: 26998086
Journal: J Exp Clin Cancer Res. 2016 Apr 2;35:63.
Title: Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cgamma1 and the ERK1/2 pathway.
Author: Ertao, Zhai|Jianhui, Chen|Chuangqi, Chen|Changjiang, Qin|Sile, Chen|Yulong, He|Hui, Wu|Shirong, Cai
PMID: 27039174
Journal: Oncogene. 2016 Dec 1;35(48):6189-6202.
Title: MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.
Author: Venturutti, L|Cordo Russo, R I|Rivas, M A|Mercogliano, M F|Izzo, F|Oakley, R H|Pereyra, M G|De Martino, M|Proietti, C J|Yankilevich, P|Roa, J C|Guzman, P|Cortese, E|Allemand, D H|Huang, T H|Charreau, E H|Cidlowski, J A|Schillaci, R|Elizalde, P V
PMID: 27157613
Journal: Cell Physiol Biochem. 2016;38(5):1939-51.
Title: Periplocin Extracted from Cortex Periplocae Induced Apoptosis of Gastric Cancer Cells via the ERK1/2-EGR1 Pathway.
Author: Li, Lei|Zhao, Lian-Mei|Dai, Su-Li|Cui, Wen-Xuan|Lv, Hui-Lai|Chen, Liang|Shan, Bao-En
PMID: 27160973
Journal: Oncol Rep. 2016 Jul;36(1):448-54.
Title: Tspan9 inhibits the proliferation, migration and invasion of human gastric cancer SGC7901 cells via the ERK1/2 pathway.
Author: Li, Pai-Yun|Lv, Jing|Qi, Wei-Wei|Zhao, Shu-Fen|Sun, Li-Bin|Liu, Ning|Sheng, Jie|Qiu, Wen-Sheng
PMID: 27177197
Journal: Anticancer Drugs. 2016 Aug;27(7):651-9.
Title: Suppressive effects on cell proliferation and motility in gastric cancer SGC-7901 cells by introducing ulinastatin in vitro.
Author: Wang, Junqing|Chen, Xuehua|Su, Liping|Zhu, Zhenggang|Wu, Weize|Zhou, Yunyun
PMID: 27187019
Journal: Mol Med Rep. 2016 Aug;14(2):1430-8.
Title: MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo.
Author: Li, Hong-Li|Wu, Hui|Zhang, Bei-Bei|Shi, Hai-Lian|Wu, Xiao-Jun
PMID: 27278862
Journal: Toxicology. 2016 Jun 15;361-362:24-38.
Title: Carbon monoxide releasing molecule-2 ameliorates IL-1beta-induced IL-8 in human gastric cancer cells.
Author: Lian, Sen|Xia, Yong|Ung, Trong Thuan|Khoi, Pham Ngoc|Yoon, Hyun Joong|Kim, Nam Ho|Kim, Kyung Keun|Jung, Young Do
PMID: 27393034
Journal: Oncotarget. 2016 Sep 20;7(38):61021-61035.
Title: The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines.
Author: Carino, Adriana|Graziosi, Luigina|D'Amore, Claudio|Cipriani, Sabrina|Marchiano, Silvia|Marino, Elisabetta|Zampella, Angela|Rende, Mario|Mosci, Paolo|Distrutti, Eleonora|Donini, Annibale|Fiorucci, Stefano
PMID: 27409173
Journal: Oncol Rep. 2016 Sep;36(3):1686-92.
Title: CXCR3A contributes to the invasion and metastasis of gastric cancer cells.
Author: Yang, Chenggang|Zheng, Wanlei|Du, Wenfeng
PMID: 27461521
Journal: Oncotarget. 2016 Sep 20;7(38):61390-61402.
Title: Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling.
Author: Jiang, Mingzuo|Qiu, Zhaoyan|Zhang, Song|Fan, Xing|Cai, Xiqiang|Xu, Bing|Li, Xiaowei|Zhou, Jinfeng|Zhang, Xiangyuan|Chu, Yi|Wang, Weijie|Liang, Jie|Horvath, Tamas|Yang, Xiaoyong|Wu, Kaichun|Nie, Yongzhan|Fan, Daiming
PMID: 27542217
Journal: Am J Transl Res. 2016 Aug 15;8(8):3522-9. eCollection 2016.
Title: Long non-coding RNA CASC2 suppresses the proliferation of gastric cancer cells by regulating the MAPK signaling pathway.
Author: Li, Peng|Xue, Wan-Jiang|Feng, Ying|Mao, Qin-Sheng
PMID: 27648142
Journal: Am J Cancer Res. 2016 Aug 1;6(8):1741-57. eCollection 2016.
Title: DEC2 suppresses tumor proliferation and metastasis by regulating ERK/NF-kappaB pathway in gastric cancer.
Author: Li, Ping|Jia, Yan-Fei|Ma, Xiao-Li|Zheng, Yan|Kong, Yi|Zhang, Yao|Zong, Shuai|Chen, Zhi-Tao|Wang, Yun-Shan
PMID: 27648362
Journal: Food Funct. 2016 Nov 9;7(11):4605-4613.
Title: Inhibition of cell proliferation and triggering of apoptosis by agrimonolide through MAP kinase (ERK and p38) pathways in human gastric cancer AGS cells.
Author: Teng, Hui|Huang, Qun|Chen, Lei
PMID: 27747355
Journal: Oncotarget. 2016 Dec 6;7(49):81062-81076.
Title: YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo.
Author: Sun, Dan|Li, Xiaoting|He, Yingjian|Li, Wenhui|Wang, Ying|Wang, Huan|Jiang, Shanshan|Xin, Yan
PMID: 27835600
Journal: Mol Carcinog. 2017 Feb;56(2):664-680.
Title: Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells.
Author: Lian, Sen|Xia, Yong|Ung, Trong Thuan|Khoi, Pham Ngoc|Yoon, Hyun Joong|Lee, Sam Gyu|Kim, Kyung Keun|Jung, Young Do
PMID: 27377703
Journal: J Recept Signal Transduct Res. 2017 Apr;37(2):174-180.
Title: Dihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways.
Author: Zhang, Shuyi|Shi, Lei|Ma, Hongwen|Li, Hongzhou|Li, Yanru|Lu, Ying|Wang, Qiaoping|Li, Wen
PMID: 27401020
Journal: Pathobiology. 2017;84(1):16-24.
Title: Overexpression of KIF11 in Gastric Cancer with Intestinal Mucin Phenotype.
Author: Imai, Takeharu|Oue, Naohide|Nishioka, Masahiro|Mukai, Shoichiro|Oshima, Takashi|Sakamoto, Naoya|Sentani, Kazuhiro|Matsusaki, Keisuke|Yoshida, Kazuhiro|Yasui, Wataru
PMID: 27459100
Journal: Oncogene. 2017 Mar 30;36(13):1873-1886.
Title: Transducin (beta)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Author: Zhou, Q|Wang, X|Yu, Z|Wu, X|Chen, X|Li, J|Zhu, Z|Liu, B|Su, L
PMID: 27694893
Journal: Oncol Res. 2017 Sep 21;25(8):1399-1407.
Title: Gastrin Enhances Autophagy and Promotes Gastric Carcinoma Proliferation via Inducing AMPKalpha.
Author: Kun, Zhuang|Hanqing, Guo|Hailing, Tang|Yuan, Yan|Jun, Zhang|Lingxia, Zhang|Kun, Han|Xin, Zhang
PMID: 28059052
Journal: Sci Rep. 2017 Jan 19;7:40802.
Title: Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation.
Author: Yu, Huangfei|Xia, Hongwei|Tang, Qiulin|Xu, Huanji|Wei, Guoqing|Chen, Ying|Dai, Xinyu|Gong, Qiyong|Bi, Feng
PMID: 28102288
Journal: Oncol Res. 2017 Aug 7;25(7):1169-1176.
Title: MicroRNA-133a Inhibits Proliferation of Gastric Cancer Cells by Downregulating ERBB2 Expression.
Author: Li, Chang|Li, Xiaoping|Gao, Shuohui|Li, Chang|Ma, Lianjun
PMID: 28109082
Journal: Exp Cell Res. 2017 Mar 1;352(1):34-44.
Title: Pseudolaric acid B inhibits gastric cancer cell metastasis in vitro and in haematogenous dissemination model through PI3K/AKT, ERK1/2 and mitochondria-mediated apoptosis pathways.
Author: Wang, Dan|Xin, Yan|Tian, Yanqiu|Li, Wenhui|Sun, Dan|Yang, Yi
PMID: 28132880
Journal: Sci Rep. 2017 Feb 6;7:42089.
Title: GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer.
Author: Shimizu, Dai|Kanda, Mitsuro|Tanaka, Haruyoshi|Kobayashi, Daisuke|Tanaka, Chie|Hayashi, Masamichi|Iwata, Naoki|Niwa, Yukiko|Takami, Hideki|Yamada, Suguru|Fujii, Tsutomu|Nakayama, Goro|Fujiwara, Michitaka|Kodera, Yasuhiro
PMID: 28165032
Journal: Cancer Gene Ther. 2017 Apr;24(4):180-188.
Title: Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition.
Author: Yin, H|Huang, X|Tao, M|Hu, Q|Qiu, J|Chen, W|Wu, J|Xie, Y
PMID: 28186089
Journal: Oncotarget. 2017 Mar 28;8(13):21454-21460.
Title: Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells.
Author: Wu, Zijian|Li, Ying
PMID: 28206955
Journal: Altern Ther Health Med. 2017 Sep;23(5):42-48.
Title: Proapoptotic and Growth-inhibitory Effects of Plumbagin on Human Gastric Cancer Cells Via Suppression of Signal Transducer and Activator of Transcription 3 and Protein Kinase B.
Author: Li, Jing|Li, Jia|Cai, Guowei|Shen, Lin|Lu, Furong
PMID: 28236621
Journal: Cell Death Dis. 2017 Mar 2;8(3):e2642.
Title: Nuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 and CD82 in gastric cancer.
Author: Xu, Liyun|Hou, Yixuan|Tu, Gang|Chen, Yanlin|Du, Yan-E|Zhang, Hailong|Wen, Siyang|Tang, Xi|Yin, Jiali|Lang, Lei|Sun, Kexin|Yang, Guanglun|Tang, Xiaoli|Liu, Manran
PMID: 28252644
Journal: Cancer Biomark. 2017;19(1):11-20.
Title: microRNA-203 suppresses invasion of gastric cancer cells by targeting ERK1/2/Slug/ E-cadherin signaling.
Author: Gao, Peng|Wang, Shijie|Jing, Fuchun|Zhan, Jiang|Wang, Yunhui
PMID: 28269747
Journal: Scand J Gastroenterol. 2017 Jun - Jul;52(6-7):745-753.
Title: CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways.
Author: Shi, Ameng|Shi, Haitao|Dong, Lei|Xu, Shaoxian|Jia, Miao|Guo, Xiaoyan|Wang, Ting
PMID: 28281844
Journal: Nanomaterials (Basel). 2017 Jan 13;7(1). pii: nano7010018.
Title: Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells.
Author: Wittig, Anja|Gehrke, Helge|Del Favero, Giorgia|Fritz, Eva-Maria|Al-Rawi, Marco|Diabate, Silvia|Weiss, Carsten|Sami, Haider|Ogris, Manfred|Marko, Doris
PMID: 28336852
Journal: Oncotarget. 2017 May 23;8(21):34516-34524.
Title: NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization.
Author: Sui, Hong|Wang, Kaibing|Xie, Rui|Li, Xi|Li, Kunpeng|Bai, Yuxian|Wang, Xishan|Bai, Bin|Chen, Dan|Li, Jiazhuang|Shen, Baozhong
PMID: 28388537
Journal: Oncotarget. 2017 Apr 25;8(17):29067-29079.
Title: A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer.
Author: Sun, Zu-Jun|Wu, Yi|Hou, Wei-Hua|Wang, Yu-Xiong|Yuan, Qing-Yun|Wang, Hui-Jie|Yu, Min
PMID: 28404966
Journal: Molecules. 2017 Apr 17;22(4). pii: molecules22040628.
Title: Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells.
Author: Zhang, Lei|Wang, Jing|Liu, Lai|Zheng, Chengyue|Wang, Yang
PMID: 28420180
Journal: J Transl Med. 2017 May 1;15(1):92.
Title: Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.
Author: Chen, Ina|Mathews-Greiner, Lesley|Li, Dandan|Abisoye-Ogunniyan, Abisola|Ray, Satyajit|Bian, Yansong|Shukla, Vivek|Zhang, Xiaohu|Guha, Raj|Thomas, Craig|Gryder, Berkley|Zacharia, Athina|Beane, Joal D|Ravichandran, Sarangan|Ferrer, Marc|Rudloff, Udo
PMID: 28460635
Journal: J Cell Biochem. 2017 Dec;118(12):4444-4453.
Title: Bradykinin Promotes Cell Proliferation, Migration, Invasion, and Tumor Growth of Gastric Cancer Through ERK Signaling Pathway.
Author: Wang, Guojun|Sun, Junfeng|Liu, Guanghui|Fu, Yang|Zhang, Xiefu
PMID: 28464378
Journal: Sci Rep. 2017 Jun 9;7(1):3153.
Title: FPR2 promotes invasion and metastasis of gastric cancer cells and predicts the prognosis of patients.
Author: Hou, Xi-Lu|Ji, Cheng-Dong|Tang, Jun|Wang, Yan-Xia|Xiang, Dong-Fang|Li, Hai-Qing|Liu, Wei-Wei|Wang, Jiao-Xue|Yan, He-Zhong|Wang, Yan|Zhang, Peng|Cui, You-Hong|Wang, Ji-Ming|Bian, Xiu-Wu|Liu, Wei
PMID: 28600569
Journal: Oncogenesis. 2017 Jul 31;6(7):e368.
Title: MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2-ERK1/2 signaling pathway by upregulating GIT1.
Author: Zhao, L Y|Tong, D D|Xue, M|Ma, H L|Liu, S Y|Yang, J|Liu, Y X|Guo, B|Ni, L|Liu, L Y|Qin, Y N|Wang, L M|Zhao, X G|Huang, C
PMID: 28759023
Journal: Med Sci Monit. 2017 Jul 31;23:3715-3721.
Title: Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway.
Author: Jin, Jiaoyue|Lv, Hang|Wu, Junzhou|Li, Dan|Chen, Kaiyan|Zhang, Fanrong|Han, Jing|Feng, Jianguo|Zhang, Nan|Yu, Herbert|Su, Dan|Ying, Lisha
PMID: 28759561
Journal: Oncol Rep. 2017 Oct;38(4):2325-2334.
Title: EGF-induced urokinase plasminogen activator receptor promotes epithelial to mesenchymal transition in human gastric cancer cells.
Author: Wang, Pingping|Ma, Maoyuan|Zhang, Shanhui
PMID: 28849196
Journal: Sci Rep. 2017 Sep 8;7(1):11057.
Title: Creation and Initial Characterization of Isogenic Helicobacter pylori CagA EPIYA Variants Reveals Differential Activation of Host Cell Signaling Pathways.
Author: Bridge, Dacie R|Blum, Faith C|Jang, Sungil|Kim, Jinmoon|Cha, Jeong-Heon|Merrell, D Scott
PMID: 28887533
Journal: Mol Med Rep. 2017 Dec;16(6):8977-8982.
Title: Antitumor effects of bakuchiol on human gastric carcinoma cell lines are mediated through PI3K/AKT and MAPK signaling pathways.
Author: Lv, Long|Liu, Bo
PMID: 28990045
Journal: Sci Rep. 2017 Oct 16;7(1):12813.
Title: Store-operated Ca(2+) Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells.
Author: Wong, Jhen-Hong|Ho, Kuo-Hao|Nam, Sean|Hsu, Wen-Li|Lin, Chia-Hsien|Chang, Che-Mai|Wang, Jaw-Yuan|Chang, Wei-Chiao
PMID: 29038542
Journal: Oncotarget. 2017 Aug 12;8(45):78757-78766.
Title: ERp29 inhibits tumorigenicity by suppressing epithelial mesenchymal transition in gastric cancer.
Author: Wu, Jing|Yang, Yuanyan|Gao, Shenshen|Jiang, Hong|Wang, Xin-Qiong|Xiao, Yuan|Chen, Xue-Hua|Li, Pu|Xu, Chun-Di
PMID: 29108263
Journal: Mol Med Rep. 2017 Dec;16(6):9295-9300.
Title: Effects of WD3 on tumor growth and the expression of integrin alphavbeta3 and ERK1/2 in mice bearing human gastric cancer using the 18FRGD PET/CT imaging system.
Author: Jin, Chunhui|Zhang, Bao-Nan|Wei, Zhipeng|Ma, Bo|Pan, Qi|Hu, Pingping
PMID: 29152665
Journal: Front Cell Infect Microbiol. 2018 Jan 15;7:541.
Title: Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway.
Author: Gunawardhana, Niluka|Jang, Sungil|Choi, Yun Hui|Hong, Youngmin A|Jeon, Yeong-Eui|Kim, Aeryun|Su, Hanfu|Kim, Ji-Hye|Yoo, Yun-Jung|Merrell, D Scott|Kim, Jinmoon|Cha, Jeong-Heon
PMID: 29379775
Journal: Integr Cancer Ther. 2018 Jun;17(2):511-523.
Title: Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-kappab, PKC-delta, ERK1/2, and AMPKalpha.
Author: Li, Hai|Chen, Chen
PMID: 28627240
Journal: Anticancer Drugs. 2018 Jan;29(1):19-28.
Title: Cell cycle-dependent translocation and regulatory mechanism of CacyBP/SIP in gastric cancer cells.
Author: Chen, Yang|Zhang, Kun|Wang, Xiaosu|Li, Qiaoneng|Wu, Qingfeng|Ning, Xiaoxuan
PMID: 29099417
Journal: Pathobiology. 2018;85(3):192-200.
Title: Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.
Author: Oue, Naohide|Yamamoto, Yuji|Oshima, Takashi|Asai, Ryuichi|Ishikawa, Akira|Uraoka, Naohiro|Sakamoto, Naoya|Sentani, Kazuhiro|Yasui, Wataru
PMID: 29131081
Journal: J Ethnopharmacol. 2018 Apr 24;216:239-250.
Title: Gastroprotective effects of Hwanglyeonhaedok-tang against Helicobacter pylori-induced gastric cell injury.
Author: Park, Hee-Seon|Wijerathne, Charith U B|Jeong, Hye-Yun|Seo, Chang-Seob|Ha, Hyekyung|Kwun, Hyo-Jung
PMID: 29410309
Journal: Oncol Lett. 2018 Feb;15(2):2147-2152.
Title: Knockdown of Arf6 increases drug sensitivity and inhibits proliferation, migration and invasion in gastric cancer SGC-7901 cells.
Author: Qiu, Junlan|Tao, Liang|Wei, Qiang|Zhang, Pingyang
PMID: 29434918
Journal: Clin Transl Med. 2018 Feb 22;7(1):7.
Title: Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk.
Author: Li, Dandan|Lo, Winifred|Rudloff, Udo
PMID: 29468433
Journal: Exp Mol Med. 2018 Feb 23;50(2):e449.
Title: Inhibition of TNFalpha-interacting protein alpha (Tipalpha)-associated gastric carcinogenesis by BTG2(/TIS21) via downregulating cytoplasmic nucleolin expression.
Author: Devanand, Preethi|Oya, Yukiko|Sundaramoorthy, Santhoshkumar|Song, Kye Yong|Watanabe, Tatsuro|Kobayashi, Yasuhito|Shimizu, Yoshihiko|Hong, Soon Auck|Suganuma, Masami|Lim, In Kyoung
PMID: 29472702
Journal: Oncol Rep. 2018 Apr;39(4):1843-1852.
Title: Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner.
Author: Wang, Qingling|Yang, Hongli|Zhuo, Qian|Xu, Yanyan|Zhang, Peng
PMID: 29484413
Journal: Cancer Res. 2018 Jun 1;78(11):3041-3053.
Title: Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 Signaling.
Author: Ji, Cheng-Dong|Wang, Yan-Xia|Xiang, Dong-Fang|Liu, Qiang|Zhou, Zhi-Hua|Qian, Feng|Yang, Lang|Ren, Yong|Cui, Wei|Xu, Sen-Lin|Zhao, Xi-Long|Zhang, Xia|Wang, Yan|Zhang, Peng|Wang, Ji-Ming|Cui, You-Hong|Bian, Xiu-Wu
PMID: 29549164
Journal: Invest New Drugs. 2018 Mar 17. pii: 10.1007/s10637-018-0584-y.
Title: The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a']diisoquinoline derivatives in human gastric cancer cells.
Author: Pawlowska, Natalia|Gornowicz, Agnieszka|Bielawska, Anna|Surazynski, Arkadiusz|Szymanowska, Anna|Czarnomysy, Robert|Bielawski, Krzysztof
PMID: 29549610
Journal: Cell Biol Int. 2018 Aug;42(8):975-984.
Title: TRPC1/3/6 inhibition attenuates the TGF-beta1-induced epithelial-mesenchymal transition in gastric cancer via the Ras/Raf1/ERK signaling pathway.
Author: Ge, Pengbo|Wei, Linting|Zhang, Mingkai|Hu, Baoguang|Wang, Kai|Li, Yanbin|Liu, Shuaichen|Wang, Jianping|Li, Yuming
PMID: 29570903
Journal: Biochem Biophys Res Commun. 2018 Jun 2;500(2):411-417.
Title: Methylation-induced silencing of SPG20 facilitates gastric cancer cell proliferation by activating the EGFR/MAPK pathway.
Author: Zhou, Zhangjian|Wang, Wei|Xie, Xin|Song, Yongchun|Dang, Chengxue|Zhang, Hao
PMID: 29673586
Journal: Oncol Rep. 2018 Jun;39(6):2942-2950.
Title: Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades.
Author: Wang, Xiaona|Zhu, Yanyan|Zhu, Lili|Chen, Xinhuan|Xu, Yanyan|Zhao, Yafei|Shao, Yingzhe|Li, Feng|Jiang, Yanan|Lu, Jing|Huang, Youtian|Chang, Xiaobin|Zhang, Juan|Li, Xiang|Liu, Kangdong|Zhao, Mingyao|Dong, Ziming|Zhao, Jimin
PMID: 29693162
Journal: Gastric Cancer. 2018 Apr 25. pii: 10.1007/s10120-018-0829-7.
Title: Cancer-adipose tissue interaction and fluid flow synergistically modulate cell kinetics, HER2 expression, and trastuzumab efficacy in gastric cancer.
Author: Akutagawa, Takashi|Aoki, Shigehisa|Yamamoto-Rikitake, Mihoko|Iwakiri, Ryuichi|Fujimoto, Kazuma|Toda, Shuji
PMID: 29696406
Journal: Oncol Lett. 2018 May;15(5):7537-7544.
Title: MAPK/c-Jun signaling pathway contributes to the upregulation of the anti-apoptotic proteins Bcl-2 and Bcl-xL induced by Epstein-Barr virus-encoded BARF1 in gastric carcinoma cells.
Author: Zhang, Yuqiong|Xu, Meiqin|Zhang, Xueyi|Chu, Fuying|Zhou, Tianji
PMID: 29725459
Journal: Gastroenterol Res Pract. 2018 Mar 21;2018:2968252.
Title: DAB2IP Downregulation Enhances the Proliferation and Metastasis of Human Gastric Cancer Cells by Derepressing the ERK1/2 Pathway.
Author: Sun, Liang|Yao, Yizhou|Lu, Ting|Shang, Zengfu|Zhan, Shenghua|Shi, Weiqiang|Pan, Guofeng|Zhu, Xinguo|He, Songbing
PMID: 29743885
Journal: Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F469-F478.
Title: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity.
Author: Sun, Liping|Liu, Jing|Yuan, Yanggang|Zhang, Xinzhou|Dong, Zheng
PMID: 29767555
Journal: Oncol Lett. 2018 Jun;15(6):8442-8446.
Title: Fisetin inhibits the proliferation of gastric cancer cells and induces apoptosis through suppression of ERK 1/2 activation.
Author: Yan, Weixin|Chen, Shouhui|Zhao, Yiyang|Ye, Xiaoyu
PMID: 29805580
Journal: Onco Targets Ther. 2018 May 17;11:2911-2923.
Title: miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R.
Author: Liu, Na|Yang, Hua|Wang, Hong
PMID: 29844688
Journal: Bioorg Med Chem Lett. 2018 Aug 1;28(14):2561-2565.
Title: Synthesis and antitumor activity of novel 6,7,8-trimethoxy N-aryl-substituted-4-aminoquinazoline derivatives.
Author: Liu, Fang|Huai, Ziyou|Xia, Guotai|Song, Liuping|Li, Sha|Xu, Yulan|Hong, Kangjun|Yao, Mingyue|Liu, Gang|Huang, Yinjiu
PMID: 29903662
Journal: Oncol Rep. 2018 Aug;40(2):1185-1195.
Title: HGF derived from cancerassociated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.
Author: Ding, Xusheng|Xi, Wenqi|Ji, Jun|Cai, Qu|Jiang, Jinling|Shi, Min|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 29917165
Journal: Oncol Lett. 2018 Aug;16(2):1565-1570.
Title: EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis in vitro through activating ERK1/2 and AKT in a PAR1-dependent manner.
Author: Wang, Qingling|Tang, Yangyang|Wang, Tianyuan|Yang, Hong-Li|Wang, Xinyue|Ma, Hongru|Zhang, Peng
PMID: 30008838
Journal: J Cell Biochem. 2018 Jul 16.
Title: Effect of 5-fluorouracil on excision repair cross-complementing 1 expression and consequent cytotoxicity regulation in human gastric cancer cells.
Author: Liu, Jing-Lan|Huang, Wen-Shih|Lee, Ko-Chao|Tung, Shui-Yi|Chen, Cheng-Nan|Chang, Shun-Fu
PMID: 30011079
Journal: Biomed Pharmacother. 2018 Sep;105:1269-1275.
Title: Yes-associated protein enhances proliferation and attenuates sensitivity to cisplatin in human gastric cancer cells.
Author: Lu, Ting|Sun, Liang|Zhu, Xinguo
PMID: 30021363
Journal: Int J Biochem Cell Biol. 2018 Sep;102:128-137.
Title: Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor.
Author: Lee, Suk-Young|Na, Yoo Jin|Jeong, Yoon A|Kim, Jung Lim|Oh, Sang Cheul|Lee, Dae-Hee
PMID: 30044964
Journal: Biomol Ther (Seoul). 2018 Jul 30. pii: biomolther.2018.091.
Title: Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with in vitro Anti-Tumor Effects.
Author: Ndolo, Karyn Muzinga|An, Su Jin|Park, Kyeong Ryang|Lee, Hyo Jeong|Yoon, Kyoung Bin|Kim, Yong-Chul|Han, Sun-Young
PMID: 30060294
Journal: Oncol Rep. 2018 Oct;40(4):2316-2324.
Title: Identification of the potential molecular mechanism and driving mutations in the pathogenesis of familial intestinal gastric cancer by whole exome sequencing.
Author: Chen, Haixiang|Wang, Juan|Zhuang, Yi|Wu, Hao
PMID: 30106433
Journal: Biomed Pharmacother. 2018 Nov;107:841-848.
Title: Knockdown of TMPRSS3 inhibits gastric cancer cell proliferation, invasion and EMT via regulation of the ERK1/2 and PI3K/Akt pathways.
Author: Li, Shun-Le|Chen, Xi|Wu, Tao|Zhang, Xin-Wu|Li, Hua|Zhang, Yan|Ji, Zong-Zheng
PMID: 30142546
Journal: BMC Complement Altern Med. 2018 Sep 10;18(1):250.
Title: Weipixiao attenuate early angiogenesis in rats with gastric precancerous lesions.
Author: Zeng, Jinhao|Yan, Ran|Pan, Huafeng|You, Fengming|Cai, Tiantian|Liu, Wei|Zheng, Chuan|Zhao, Ziming|Gong, Daoyin|Chen, Longhui|Zhang, Yi
PMID: 30200948
Journal: Transl Oncol. 2018 Dec;11(6):1379-1389.
Title: Sorcin a Potential Molecular Target for Cancer Therapy.
Author: Shabnam, Bano|Padmavathi, Ganesan|Banik, Kishore|Girisa, Sosmitha|Monisha, Javadi|Sethi, Gautam|Fan, Lu|Wang, Lingzhi|Mao, Xinliang|Kunnumakkara, Ajaikumar B
PMID: 30216763
Journal: Cell Death Dis. 2018 Sep 24;9(10):998.
Title: Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer.
Author: Chen, Di|Xu, Li|Li, Xiaowei|Chu, Yi|Jiang, Mingzuo|Xu, Bing|Zhao, Min|Wang, Weijie|Wang, Hua|Kang, Huijie|Wang, Kai|Wu, Kaichun|Liang, Jie|Ren, Gui
PMID: 30250066
Journal: Histopathology. 2018 Oct 11.
Title: Clinicopathological significance of RCAN2 production in gastric carcinoma.
Author: Hattori, Yui|Sentani, Kazuhiro|Shinmei, Shunsuke|Oo, Htoo Zarni|Hattori, Takuya|Imai, Takeharu|Sekino, Yohei|Sakamoto, Naoya|Oue, Naohide|Niitsu, Hiroaki|Hinoi, Takao|Ohdan, Hideki|Yasui, Wataru
PMID: 30307052
Journal: Cell Cycle. 2018 Nov 1.
Title: Up-regulation of microRNA-497 inhibits the proliferation, migration and invasion but increases the apoptosis of multiple myeloma cells through the MAPK/ERK signaling pathway by targeting Raf-1.
Author: Ye, Cheng-Yu|Zheng, Cui-Ping|Ying, Wei-Wei|Weng, Shan-Shan
PMID: 30382763