Primary Site >> Colorectal Cancer

Gene >> MAPK14

Journal: Oncogene. 1997 Nov 27;15(22):2705-16.
Title: ErbB kinases and NDF signaling in human prostate cancer cells.
Author: Grasso, A W|Wen, D|Miller, C M|Rhim, J S|Pretlow, T G|Kung, H J
PMID: 9400997
Journal: Cancer Res. 1998 Jun 1;58(11):2339-42.
Title: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
Author: Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E
PMID: 9622070
Journal: Anticancer Res. 1999 Nov-Dec;19(6B):5283-91.
Title: Involvement of p38 MAP kinase in apoptotic and proliferative alteration in human colorectal cancers.
Author: Miki, H|Yamada, H|Mitamura, K
PMID: 10697550
Journal: Cancer Res. 2000 Apr 1;60(7):2007-17.
Title: Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways.
Author: Remacle-Bonnet, M M|Garrouste, F L|Heller, S|Andre, F|Marvaldi, J L|Pommier, G J
PMID: 10766192
Journal: Clin Cancer Res. 2000 May;6(5):2021-7.
Title: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Author: Whitacre, C M|Feyes, D K|Satoh, T|Grossmann, J|Mulvihill, J W|Mukhtar, H|Oleinick, N L
PMID: 10815928
Journal: J Biol Chem. 2000 Sep 8;275(36):28173-9.
Title: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.
Author: Paik, J H|Ju, J H|Lee, J Y|Boudreau, M D|Hwang, D H
PMID: 10866999
Journal: Biochem J. 2000 Dec 1;352 Pt 2:419-24.
Title: Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.
Author: McGinty, A|Foschi, M|Chang, Y W|Han, J|Dunn, M J|Sorokin, A
PMID: 11085935
Journal: FASEB J. 2001 Feb;15(2):362-72.
Title: PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.
Author: Ilan, N|Mohsenin, A|Cheung, L|Madri, J A
PMID: 11156952
Journal: Carcinogenesis. 2001 Jan;22(1):35-41.
Title: Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis.
Author: Qiao, D|Stratagouleas, E D|Martinez, J D
PMID: 11159738
Journal: Gastroenterology. 2001 Feb;120(2):401-10.
Title: Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells.
Author: Glinghammar, B|Rafter, J
PMID: 11159881
Journal: Oncogene. 2001 Feb 15;20(7):819-27.
Title: NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps.
Author: Hardwick, J C|van den Brink, G R|Offerhaus, G J|van Deventer, S J|Peppelenbosch, M P
PMID: 11314016
Journal: J Surg Res. 2001 May 1;97(1):60-4.
Title: Epithelial cyclooxygenase-2 expression: a model for pathogenesis of colon cancer.
Author: Arbabi, S|Rosengart, M R|Garcia, I|Jelacic, S|Maier, R V
PMID: 11319881
Journal: Biochem Biophys Res Commun. 2001 Jun 8;284(2):282-8.
Title: Alterations of MAPK activities associated with intestinal cell differentiation.
Author: Ding, Q|Wang, Q|Evers, B M
PMID: 11394874
Journal: Int J Colorectal Dis. 2001 Jun;16(3):167-73.
Title: Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells.
Author: Kim, T I|Jin, S H|Kim, W H|Kang, E H|Choi, K Y|Kim, H J|Shin, S K|Kang, J K
PMID: 11459290
Journal: Int J Oncol. 2001 Sep;19(3):613-6.
Title: DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells.
Author: Jaiswal, A S|Narayan, S
PMID: 11494044
Journal: Oncogene. 2001 Dec 6;20(56):8066-74.
Title: Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells.
Author: Yao, J|Xiong, S|Klos, K|Nguyen, N|Grijalva, R|Li, P|Yu, D
PMID: 11781819
Journal: Angiogenesis. 2001;4(2):155-62.
Title: Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway.
Author: Jung, Y D|Liu, W|Reinmuth, N|Ahmad, S A|Fan, F|Gallick, G E|Ellis, L M
PMID: 11806247
Journal: Gastroenterology. 2002 Apr;122(4):985-93.
Title: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
Author: Yoon, Jung-Hwan|Higuchi, Hajime|Werneburg, Nathan W|Kaufmann, Scott H|Gores, Gregory J
PMID: 11910351
Journal: J Biol Chem. 2002 Jul 12;277(28):25040-6. Epub 2002 Apr 29.
Title: Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
Author: Lim, Seunghwan|Jin, Kideok|Friedman, Eileen
PMID: 11980910
Journal: Cell Death Differ. 2002 Jul;9(7):768-79.
Title: Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.
Author: Garrouste, F|Remacle-Bonnet, M|Fauriat, C|Marvaldi, J|Luis, J|Pommier, G
PMID: 12058282
Journal: J Biol Chem. 2002 Sep 6;277(36):32624-31. Epub 2002 Jun 20.
Title: Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kappa B.
Author: Lee, Hae-Wan|Ahn, Dae-Ho|Crawley, Suzanne C|Li, Jian-Dong|Gum, James R Jr|Basbaum, Carol B|Fan, Nancy Q|Szymkowski, David E|Han, Sang-Young|Lee, Bong H|Sleisenger, Marvin H|Kim, Young S
PMID: 12077118
Journal: Photochem Photobiol. 2002 Jul;76(1):98-104.
Title: Up-regulation of Hsp27 plays a role in the resistance of human colon carcinoma HT29 cells to photooxidative stress.
Author: Wang, Hong P|Hanlon, John G|Rainbow, Andrew J|Espiritu, Myrna|Singh, Gurmit
PMID: 12126313
Journal: Mol Carcinog. 2002 Sep;35(1):21-8.
Title: Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Author: Lin, Shyr-Yi|Liang, Yu-Chih|Ho, Yuan-Soon|Tsai, Shu-Huei|Pan, Shiann|Lee, Wen-Sen
PMID: 12203364
Journal: FEBS Lett. 2002 Sep 11;527(1-3):109-13.
Title: Human gastrin-releasing peptide receptor mediates sustained CREB phosphorylation and transactivation in HuTu 80 duodenal cancer cells.
Author: Qu, Xiangping|Xiao, Dongmei|Weber, H Christian
PMID: 12220644
Journal: Toxicol Appl Pharmacol. 2002 Sep 15;183(3):160-7.
Title: Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation.
Author: Patten Hitt, Emma|DeLong, Mary J|Merrill, Alfred H Jr
PMID: 12383707
Journal: Ann N Y Acad Sci. 2002 Nov;973:241-5.
Title: The role of mitogen-activated protein kinases and their relationship with NF-kappaB and PPARgamma in indomethacin-Induced apoptosis of colon cancer cells.
Author: Kim, Tae Il|Jin, Soo Hyun|Kang, Eun Hye|Shin, Sung Kwan|Choi, Kang Yell|Kim, Won Ho
PMID: 12485869
Journal: Br J Cancer. 2003 Mar 10;88(5):748-53.
Title: Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases.
Author: McMillan, L|Butcher, S K|Pongracz, J|Lord, J M
PMID: 12618885
Journal: Mol Biol Cell. 2003 May;14(5):1790-800. Epub 2003 Jan 26.
Title: Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids.
Author: Bates, Richard C|Mercurio, Arthur M
PMID: 12802055
Journal: Carcinogenesis. 2003 Aug;24(8):1361-7.
Title: The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
Author: Hu, Rong|Kim, Bok Ryang|Chen, Chi|Hebbar, Vidya|Kong, A-N Tony
PMID: 12819185
Journal: Cancer Sci. 2003 Mar;94(3):286-91.
Title: Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression.
Author: Satou, Mamoru|Aizawa, Syu|Hayakari, Makoto|Ookawa, Keizou|Tsuchida, Shigeki
PMID: 12824923
Journal: Cancer Res. 2003 Jul 1;63(13):3632-6.
Title: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.
Author: Liu, Wenbiao|Reinmuth, Niels|Stoeltzing, Oliver|Parikh, Alexander A|Tellez, Carmen|Williams, Simon|Jung, Young D|Fan, Fan|Takeda, Akihiko|Akagi, Morihisa|Bar-Eli, Menashe|Gallick, Gary E|Ellis, Lee M
PMID: 12839952
Journal: Life Sci. 2003 Oct 17;73(22):2817-29.
Title: MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2.
Author: Jikuhara, Atsushi|Yoshii, Masanori|Iwagaki, Hiromi|Mori, Shuji|Nishibori, Masahiro|Tanaka, Noriaki
PMID: 14511767
Journal: Anticancer Drugs. 2003 Oct;14(9):761-6.
Title: Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL.
Author: Chan, Ursula P F|Lee, Janet F Y|Wang, S H|Leung, Ka L|Chen, George G
PMID: 14551511
Journal: Cancer Sci. 2003 Oct;94(10):886-93.
Title: Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine.
Author: Aizawa, Shu|Ookawa, Keizou|Kudo, Toshihiro|Asano, Junpei|Hayakari, Makoto|Tsuchida, Shigeki
PMID: 14556662
Journal: Cancer Res. 2003 Dec 15;63(24):8600-5.
Title: Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling.
Author: Rakitina, Tatiana V|Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 14695170
Journal: Cancer Res. 2004 Jan 1;64(1):262-72.
Title: The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.
Author: Whittaker, Steven R|Walton, Mike I|Garrett, Michelle D|Workman, Paul
PMID: 14729633
Journal: J Cell Biochem. 2004 Feb 1;91(2):410-22.
Title: Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells.
Author: Choi, Kyoung-Han|Choi, Hye Young|Ko, Jae-Kyun|Park, Sung-Shin|Kim, Yong-Nyun|Kim, Chul-Woo
PMID: 14743399
Journal: Cancer Biol Ther. 2004 Mar;3(3):296-301. Epub 2004 Mar 16.
Title: Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Author: Zhang, Lidong|Zhu, Hongbo|Davis, John J|Jacob, Dietmar|Wu, Shuhong|Teraishi, Fuminori|Gutierrez, Angelica|Wang, Yibin|Fang, Bingliang
PMID: 14749540
Journal: Int J Cancer. 2004 May 10;109(6):933-40.
Title: Flavaglines: a group of efficient growth inhibitors block cell cycle progression and induce apoptosis in colorectal cancer cells.
Author: Hausott, Barbara|Greger, Harald|Marian, Brigitte
PMID: 15027128
Journal: J Biol Chem. 2004 May 21;279(21):22138-44. Epub 2004 Mar 22.
Title: p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor.
Author: Qi, Xiaomei|Tang, Jun|Pramanik, Rocky|Schultz, Richard M|Shirasawa, Senji|Sasazuki, Takehiko|Han, Jiahuai|Chen, Guan
PMID: 15037631
Journal: J Cell Physiol. 2004 May;199(2):262-73.
Title: The nucleocytoplasmic shuttling of E2F4 is involved in the regulation of human intestinal epithelial cell proliferation and differentiation.
Author: Deschenes, Claude|Alvarez, Laetitia|Lizotte, Marie-Eve|Vezina, Anne|Rivard, Nathalie
PMID: 15040009
Journal: Biochem Biophys Res Commun. 2004 Apr 30;317(2):463-71.
Title: Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition.
Author: Tong, Xin|Yin, Lei|Giardina, Charles
PMID: 15063780
Journal: Carcinogenesis. 2004 Nov;25(11):2183-9. Epub 2004 Jul 15.
Title: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick Charles
PMID: 15256484
Journal: Cancer Res. 2004 Aug 1;64(15):5162-71.
Title: Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-g
Author: Grau, Raquel|Iniguez, Miguel A|Fresno, Manuel
PMID: 15289320
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:143-50.
Title: Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.
Author: Tominaga, K|Higuchi, K|Sasaki, E|Suto, R|Watanabe, T|Fujiwara, Y|Oshitani, N|Matsumoto, T|Kim, S|Iwao, H|Arakawa, T
PMID: 15298620
Journal: Apoptosis. 2004 Sep;9(5):619-27.
Title: Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway.
Author: Chen, G G|Liang, N-C|Lee, J F Y|Chan, U P F|Wang, S H|Leung, B C S|Leung, K L
PMID: 15314290
Journal: Clin Exp Metastasis. 2004;21(3):257-64.
Title: Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4.
Author: Laferriere, Julie|Houle, Francois|Huot, Jacques
PMID: 15387376
Journal: Cell Prolif. 2004 Dec;37(6):427-41.
Title: Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals.
Author: Walsh, M F|Woo, R K-Y|Gomez, R|Basson, M D
PMID: 15548175
Journal: J Biol Chem. 2005 Mar 4;280(9):7634-44. Epub 2004 Dec 17.
Title: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
Author: Wang, Ling-Chi|Okitsu, Cindy Yen|Zandi, Ebrahim
PMID: 15611081
Journal: Mol Cancer Ther. 2005 Jan;4(1):51-9.
Title: Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells.
Author: Sun, Yunjie|Sinicrope, Frank A
PMID: 15657353
Journal: Oncogene. 2005 Apr 21;24(18):3011-9.
Title: Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.
Author: Kobayashi, Shinichiro|Nantz, Regan|Kitamura, Tetsuya|Higashikubo, Ryuji|Horikoshi, Nobuo
PMID: 15735687
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: World J Gastroenterol. 2005 May 7;11(17):2557-63.
Title: Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: roles of cyclic AMP and p38 mitogen-activated protein kinase.
Author: Liang, Yu-Chih|Wu, Chih-Hsiung|Chu, Jan-Show|Wang, Chung-Kwe|Hung, Ling-Fang|Wang, Ying-Jan|Ho, Yuan-Soon|Chang, Jan-Gowth|Lin, Shyr-Yi
PMID: 15849811
Journal: J Biol Chem. 2005 Jun 24;280(25):23910-7. Epub 2005 Apr 25.
Title: Essential role of p38gamma in K-Ras transformation independent of phosphorylation.
Author: Tang, Jun|Qi, Xiaomei|Mercola, Dan|Han, Jiahuai|Chen, Guan
PMID: 15851477
Journal: Carcinogenesis. 2005 Sep;26(9):1553-62. Epub 2005 Apr 28.
Title: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
Author: Kim, Mihye|Murakami, Akira|Kawabata, Kyuichi|Ohigashi, Hajime
PMID: 15860507
Journal: Lancet Oncol. 2005 May;6(5):322-7.
Title: The MAPK signalling pathways and colorectal cancer.
Author: Fang, Jing Yuan|Richardson, Bruce C
PMID: 15863380
Journal: Acta Otolaryngol. 2005 Feb;125(2):201-6.
Title: Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Author: Kim, Chang-Hoon|Song, Kyoung Seob|Kim, Kyung-Su|Kim, Jin Young|Lee, Bong-Jae|Lee, Jeung-Gweon|Yoon, Joo-Heon
PMID: 15880954
Journal: World J Gastroenterol. 2005 May 28;11(20):3040-5.
Title: Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells.
Author: Yang, Kuo-Ching|Uen, Yih-Huei|Suk, Fat-Moon|Liang, Yu-Chih|Wang, Ying-Jan|Ho, Yuan-Soon|Li, I-Hsuan|Lin, Shyr-Yi
PMID: 15918186
Journal: J Biol Chem. 2005 Aug 5;280(31):28230-40. Epub 2005 Jun 9.
Title: Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling.
Author: Song, Im-Sook|Tatebe, Shigeru|Dai, Wenping|Kuo, M Tien
PMID: 15946948
Journal: Cell Signal. 2005 Dec;17(12):1505-15.
Title: Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells.
Author: Yu, Hong-Gang|Schafer, Heiner|Mergler, Stefan|Muerkoster, Susanne|Cramer, Torsten|Hocker, Michael|Herzig, Karl-Heinz|Schmidt, Wolfgang E|Schmitz, Frank
PMID: 15951156
Journal: Mol Cancer Ther. 2005 Jun;4(6):901-9.
Title: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.
Author: Li, Yin|Mao, Yuehua|Brandt-Rauf, Paul W|Williams, Ann C|Fine, Robert L
PMID: 15956247
Journal: FEBS Lett. 2005 Jul 4;579(17):3683-90.
Title: The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11'-dideoxyverticillin-induced G2/M arrest.
Author: Chen, Yi|Miao, Ze-Hong|Zhao, Wei-Min|Ding, Jian
PMID: 15963507
Journal: Cancer Res. 2005 Jul 15;65(14):6159-66.
Title: The novel gene EG-1 stimulates cellular proliferation.
Author: Lu, Ming|Zhang, Liping|Maul, Raymond Scott|Sartippour, Maryam R|Norris, Andrew|Whitelegge, Julian|Rao, Jian Yu|Brooks, Mai N
PMID: 16024617
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1646-52.
Title: Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines.
Author: Fenton, Jenifer I|Hord, Norman G|Lavigne, Jackie A|Perkins, Susan N|Hursting, Stephen D
PMID: 16030096
Journal: Clin Cancer Res. 2005 Jul 15;11(14):5248-56.
Title: Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity.
Author: Minami, Takae|Adachi, Masaaki|Kawamura, Rina|Zhang, Yubin|Shinomura, Yasuhisa|Imai, Kohzoh
PMID: 16033843
Journal: Am J Pathol. 2005 Sep;167(3):761-73.
Title: Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily.
Author: Remacle-Bonnet, Maryse|Garrouste, Francoise|Baillat, Gilbert|Andre, Frederic|Marvaldi, Jacques|Pommier, Gilbert
PMID: 16127155
Journal: Apoptosis. 2005 Dec;10(6):1357-68.
Title: Photodynamic therapy-induced death of HCT 116 cells: Apoptosis with or without Bax expression.
Author: Chiu, S-M|Xue, L-Y|Azizuddin, K|Oleinick, N L
PMID: 16215676
Journal: Regul Pept. 2006 Mar 15;134(1):1-8.
Title: Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways.
Author: Ogunwobi, Olorunseun Olatunji|Beales, Ian L P
PMID: 16169610
Journal: J Pharmacol Exp Ther. 2006 Jan;316(1):25-34. Epub 2005 Sep 16.
Title: Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation.
Author: Hundley, Thomas R|Rigas, Basil
PMID: 16169935
Journal: Cancer Chemother Pharmacol. 2006 Feb;57(3):317-27. Epub 2005 Sep 17.
Title: p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.
Author: Shen, Guoxiang|Xu, Changjiang|Chen, Chi|Hebbar, Vidya|Kong, Ah-Ng Tony
PMID: 16170570
Journal: J Biol Chem. 2006 Jan 13;281(2):977-81. Epub 2005 Nov 1.
Title: Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited.
Author: Schulz, Tim J|Thierbach, Rene|Voigt, Anja|Drewes, Gunnar|Mietzner, Brun|Steinberg, Pablo|Pfeiffer, Andreas F H|Ristow, Michael
PMID: 16263703
Journal: Cell Signal. 2006 Aug;18(8):1262-9.
Title: Up-regulation of cyclooxygenase-2 by interleukin-1beta in colon carcinoma cells.
Author: Duque, Javier|Diaz-Munoz, Manuel D|Fresno, Manuel|Iniguez, Miguel A
PMID: 16326073
Journal: Int J Cancer. 2006 Jun 1;118(11):2758-64.
Title: TAK1-mediated stress signaling pathways are essential for TNF-alpha-promoted pulmonary metastasis of murine colon cancer cells.
Author: Choo, Min-Kyung|Sakurai, Hiroaki|Koizumi, Keiichi|Saiki, Ikuo
PMID: 16385569
Journal: Regul Pept. 2006 May 15;134(2-3):105-13.
Title: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells.
Author: Ogunwobi, Olorunseun Olatunji|Beales, Ian L P
PMID: 16529829
Journal: Carcinogenesis. 2006 Jul;27(7):1507-15. Epub 2006 Apr 5.
Title: Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line.
Author: Fenton, Jenifer I|Hursting, Stephen D|Perkins, Susan N|Hord, Norman G
PMID: 16597643
Journal: Cell Signal. 2006 Nov;18(11):1967-76. Epub 2006 May 3.
Title: Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis.
Author: Fassetta, Michela|D'Alessandro, Lorenza|Coltella, Nadia|Di Renzo, Maria Flavia|Rasola, Andrea
PMID: 16677802
Journal: Int J Biochem Cell Biol. 2006;38(9):1510-7. Epub 2006 Apr 6.
Title: Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway.
Author: Busserolles, Jerome|Megias, Javier|Terencio, Maria Carmen|Alcaraz, Maria Jose
PMID: 16697692
Journal: Oncogene. 2006 Oct 26;25(50):6563-73. Epub 2006 May 22.
Title: Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases.
Author: Tremblay, P-L|Auger, F A|Huot, J
PMID: 16715142
Journal: Cancer Res. 2006 Jul 15;66(14):7348-54.
Title: Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism.
Author: Ulrich, Sandra|Loitsch, Stefan M|Rau, Oliver|von Knethen, Andreas|Brune, Bernhard|Schubert-Zsilavecz, Manfred|Stein, Jurgen M
PMID: 16849586
Journal: Cancer Res. 2006 Sep 15;66(18):9117-24.
Title: Death receptor-3, a new E-Selectin counter-receptor that confers migration and survival advantages to colon carcinoma cells by triggering p38 and ERK MAPK activation.
Author: Gout, Stephanie|Morin, Chantale|Houle, Francois|Huot, Jacques
PMID: 16982754
Journal: Exp Cell Res. 2006 Dec 10;312(20):4056-69. Epub 2006 Sep 16.
Title: P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin.
Author: Reyes-Reyes, Merit E|George, Margaret D|Roberts, John D|Akiyama, Steven K
PMID: 17056038
Journal: Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17384-9.
Title: Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer.
Author: Oskouian, Babak|Sooriyakumaran, Prathap|Borowsky, Alexander D|Crans, Angelina|Dillard-Telm, Lisa|Tam, Yuen Yee|Bandhuvula, Padmavathi|Saba, Julie D
PMID: 17090686
Journal: Cell Death Differ. 2007 Apr;14(4):693-702. Epub 2006 Dec 8.
Title: A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells.
Author: Comes, F|Matrone, A|Lastella, P|Nico, B|Susca, F C|Bagnulo, R|Ingravallo, G|Modica, S|Lo Sasso, G|Moschetta, A|Guanti, G|Simone, C
PMID: 17159917
Journal: Oncol Rep. 2007 Mar;17(3):597-603.
Title: Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway.
Author: Liu, Xia|Bian, Chunjing|Ren, Kaihuan|Jin, Haixia|Li, Baowei|Shao, Rong-Guang
PMID: 17273739
Journal: Cancer Res. 2007 Feb 15;67(4):1660-9.
Title: p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells.
Author: Thoms, Hazel C|Dunlop, Malcolm G|Stark, Lesley A
PMID: 17308107
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1511-9.
Title: Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts.
Author: Hoang, Brian|Trinh, Alice|Birnbaumer, Lutz|Edwards, Robert A
PMID: 17332478
Journal: Oncol Rep. 2007 Apr;17(4):781-6.
Title: Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1.
Author: Kuwamura, Hikaru|Tominaga, Kazunari|Shiota, Masayuki|Ashida, Reiko|Nakao, Takafumi|Sasaki, Eiji|Watanabe, Toshio|Fujiwara, Yasuhiro|Oshitani, Nobuhide|Higuchi, Kazuhide|Ichijo, Hidenori|Arakawa, Tetsuo|Iwao, Hiroshi
PMID: 17342315
Journal: Endocr Relat Cancer. 2007 Mar;14(1):153-67.
Title: Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation.
Author: Galluzzo, Paola|Caiazza, Francesco|Moreno, Sandra|Marino, Maria
PMID: 17395984
Journal: Dig Dis Sci. 2007 Aug;52(8):1934-45.
Title: Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells.
Author: Ogunwobi, Olorunseun Olatunji|Beales, Ian L P
PMID: 17406816
Journal: Autophagy. 2007 Sep-Oct;3(5):468-71. Epub 2007 Apr 23.
Title: Signal-dependent control of autophagy and cell death in colorectal cancer cell: the role of the p38 pathway.
Author: Simone, Cristiano
PMID: 17495519
Journal: Apoptosis. 2007 Sep;12(9):1733-42.
Title: Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation.
Author: Bragado, Paloma|Armesilla, Alejandro|Silva, Augusto|Porras, Almudena
PMID: 17505786
Journal: Mol Cancer Ther. 2007 May;6(5):1562-71.
Title: 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.
Author: Su, Rong-Ying|Chao, Yee|Chen, Tsai-Yu|Huang, Duen-Yi|Lin, Wan-Wan
PMID: 17513605
Journal: Biochem Biophys Res Commun. 2007 Jul 20;359(1):102-7. Epub 2007 May 21.
Title: 17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells.
Author: Caiazza, Francesco|Galluzzo, Paola|Lorenzetti, Stefano|Marino, Maria
PMID: 17524358
Journal: Toxicol Appl Pharmacol. 2007 Jul 1;222(1):97-104.
Title: Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells.
Author: Hsiao, Po-Wen|Chang, Chia-Ching|Liu, Huei-Fang|Tsai, Chuan-Mei|Chiu, Ted H|Chao, Jui-I
PMID: 17540426
Journal: Zhonghua Zhong Liu Za Zhi. 2007 Jan;29(1):4-8.
Title: [The role of p38 MAPK in gastrin-induced u-PA expression in human colon cancer cells].
Author: Ming, Mei|Yu, Jie-ping|Zhou, Yan-hong|Cao, Jun|Song, Wen-chong|Yu, Hong-gang|Luo, He-sheng
PMID: 17575684
Journal: Mol Cancer Ther. 2007 Jul;6(7):2092-102.
Title: Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Author: Katayama, Kazuhiro|Yoshioka, Sho|Tsukahara, Satomi|Mitsuhashi, Junko|Sugimoto, Yoshikazu
PMID: 17620438
Journal: J Cell Sci. 2007 Aug 1;120(Pt 15):2672-82. Epub 2007 Jul 17.
Title: Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Author: Avvisato, Christopher L|Yang, Xiang|Shah, Salim|Hoxter, Becky|Li, Weiqun|Gaynor, Richard|Pestell, Richard|Tozeren, Aydin|Byers, Stephen W
PMID: 17635998
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G673-81.
Title: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.
Author: Leone, Vincenza|di Palma, Antonella|Ricchi, Paolo|Acquaviva, Fabio|Giannouli, Maria|Di Prisco, Anna Maria|Iuliano, Francesca|Acquaviva, Angela M
PMID: 17640974
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G719-28. Epub 2007 Jul
Title: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts.
Author: Di Mari, J F|Saada, J I|Mifflin, R C|Valentich, J D|Powell, D W
PMID: 17640979
Journal: Cancer Res. 2007 Aug 1;67(15):7266-74.
Title: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.
Author: Rengifo-Cam, William|Umar, Shahid|Sarkar, Shubhashish|Singh, Pomila
PMID: 17671195
Journal: Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author: Hsu, Wen-Hsiu|Hsieh, Yih-Shou|Kuo, Hsing-Chun|Teng, Chun-Yuh|Huang, Hai-I|Wang, Chau-Jong|Yang, Shun-Fa|Liou, Yi-Sheng|Kuo, Wu-Hsien
PMID: 17673978
Journal: Mol Cancer Ther. 2007 Aug;6(8):2220-9.
Title: Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
Author: Hao, Honglin|Muniz-Medina, Vanessa M|Mehta, Heena|Thomas, Nancy E|Khazak, Vladimir|Der, Channing J|Shields, Janiel M
PMID: 17699719
Journal: Surgery. 2007 Sep;142(3):384-92.
Title: Thermal sensitization through ROS modulation: a strategy to improve the efficacy of hyperthermic intraperitoneal chemotherapy.
Author: Wang, Chia-Chi|Chen, Fei|Kim, Eugene|Harrison, Lawrence E
PMID: 17723891
Journal: Biochem Biophys Res Commun. 2007 Oct 26;362(3):606-11.
Title: Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects.
Author: Corona, Giulia|Deiana, Monica|Incani, Alessandra|Vauzour, David|Dessi, M Assunta|Spencer, Jeremy P E
PMID: 17727817
Journal: Pharm Res. 2008 Feb;25(2):387-99. Epub 2007 Jul 27.
Title: Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Author: Nair, Sujit|Hebbar, Vidya|Shen, Guoxiang|Gopalakrishnan, Avantika|Khor, Tin Oo|Yu, Siwang|Xu, Changjiang|Kong, Ah-Ng
PMID: 17657594
Journal: Inflamm Bowel Dis. 2008 Feb;14(2):162-75.
Title: Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine.
Author: Subramanian, Sreedhar|Rhodes, Jonathan M|Hart, C Anthony|Tam, Ben|Roberts, Carol L|Smith, Shirley L|Corkill, John E|Winstanley, Craig|Virji, Mumtaz|Campbell, Barry J
PMID: 17941093
Journal: DNA Repair (Amst). 2008 Feb 1;7(2):239-52.
Title: Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
Author: Hill, Richard|Leidal, Andrew M|Madureira, Patricia A|Gillis, Laura D|Cochrane, Haley K|Waisman, David M|Chiu, Arthur|Lee, Patrick W K
PMID: 18024214
Journal: Br J Pharmacol. 2008 Mar;153(5):870-8. Epub 2007 Dec 17.
Title: Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29).
Author: Gallicchio, M|Rosa, A C|Dianzani, C|Brucato, L|Benetti, E|Collino, M|Fantozzi, R
PMID: 18084318
Journal: J Biol Chem. 2008 Feb 29;283(9):5533-41.
Title: A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells.
Author: Rouget, Raphael|Auclair, Yannick|Loignon, Martin|Affar, El Bachir|Drobetsky, Elliot A
PMID: 18093981
Journal: Biol Pharm Bull. 2008 Jan;31(1):79-84.
Title: Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells.
Author: Inaba, Hiroyuki|Nagaoka, Yasuo|Kushima, Yukihiro|Kumagai, Ayako|Matsumoto, Yoshinori|Sakaguchi, Minoru|Baba, Kimiye|Uesato, Shinichi
PMID: 18175946
Journal: Cancer Biol Ther. 2008 Jun;7(6):822-32. Epub 2008 Mar 4.
Title: Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.
Author: Gongora, Celine|Candeil, Laurent|Vezzio, Nadia|Copois, Virginie|Denis, Vincent|Breil, Corinne|Molina, Franck|Fraslon, Caroline|Conseiller, Emmanuel|Pau, Bernard|Martineau, Pierre|Del Rio, Maguy
PMID: 18340113
Journal: Cancer Lett. 2008 Jun 28;265(1):16-26.
Title: Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors.
Author: Chiacchiera, Fulvio|Simone, Cristiano
PMID: 18395970
Journal: Mol Cancer Ther. 2008 Apr;7(4):915-22.
Title: Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.
Author: Serova, Maria|Ghoul, Aida|Benhadji, Karim A|Faivre, Sandrine|Le Tourneau, Christophe|Cvitkovic, Esteban|Lokiec, Francois|Lord, Janet|Ogbourne, Steven M|Calvo, Fabien|Raymond, Eric
PMID: 18413805
Journal: Nutr Cancer. 2008;60(3):389-400.
Title: Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein.
Author: Khare, Sharad|Mustafi, Reba|Cerda, Sonia|Yuan, Weihua|Jagadeeswaran, Sujatha|Dougherty, Urszula|Tretiakova, Maria|Samarel, Allen|Cohen, Greg|Wang, Julia|Moore, Christopher|Wali, Ramesh|Holgren, Cory|Joseph, Loren|Fichera, Alessandro|Li, Yan Chun|Bissonnet
PMID: 18444174
Journal: AAPS J. 2008 Jun;10(2):277-81.
Title: PEITC induces G1 cell cycle arrest on HT-29 cells through the activation of p38 MAPK signaling pathway.
Author: Cheung, Ka Lung|Khor, Tin Oo|Yu, Siwang|Kong, Ah-Ng Tony
PMID: 18473178
Journal: Toxicol Lett. 2008 Jun 30;179(2):63-70.
Title: Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells.
Author: Chiu, Shu-Jun|Chao, Jui-I|Lee, Yi-Jang|Hsu, Tzu-Sheng
PMID: 18499365
Journal: Exp Cell Res. 2008 Jul 1;314(11-12):2212-23.
Title: Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells.
Author: Reyes-Reyes, E Merit|Akiyama, Steven K
PMID: 18504038
Journal: Biol Pharm Bull. 2008 Jun;31(6):1177-81.
Title: Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
Author: Nagaoka, Yasuo|Otsuki, Kota|Fujita, Tetsuro|Uesato, Shinichi
PMID: 18520051
Journal: Int J Colorectal Dis. 2008 Oct;23(10):971-8.
Title: The FVIIa-tissue factor complex induces the expression of MMP7 in LOVO cells in vitro.
Author: Zhang, Jian-Quan|Wan, Yuan-Lian|Liu, Yu-Cun|Wang, Xin|Tang, Jian-Qiang|Wu, Tao|Zhu, Jing|Pan, Yi-Sheng
PMID: 18548257
Journal: Gut. 2008 Nov;57(11):1509-17.
Title: Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.
Author: Binion, D G|Otterson, M F|Rafiee, P
PMID: 18596194
Journal: Exp Cell Res. 2008 Oct 1;314(16):3017-26.
Title: Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.
Author: Ikeda, Ryuji|Iwashita, Ken-ichi|Sumizawa, Tomoyuki|Beppu, Shun-ichi|Tabata, Sho|Tajitsu, Yusuke|Shimamoto, Yuichi|Yoshida, Kenichi|Furukawa, Tatsuhiko|Che, Xiao-Fang|Yamaguchi, Tatsuya|Ushiyama, Mina|Miyawaki, Akihiko|Takeda, Yasuo|Yamamoto, Masatatsu|Zha
PMID: 18671966
Journal: Hepatogastroenterology. 2008 May-Jun;55(84):930-5.
Title: Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells.
Author: Tsuchiya, Takeshi|Tsuno, Nelson H|Asakage, Masahiro|Yamada, Jun|Yoneyama, Satomi|Okaji, Yurai|Sasaki, Shin|Kitayama, Joji|Osada, Takuya|Takahashi, Koki|Nagawa, Hirokazu
PMID: 18705300
Journal: Cancer Res. 2008 Sep 1;68(17):7035-41.
Title: Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil.
Author: Zhao, Hong-Ye|Ooyama, Akio|Yamamoto, Masatatsu|Ikeda, Ryuji|Haraguchi, Misako|Tabata, Sho|Furukawa, Tatsuhiko|Che, Xiao-Fang|Zhang, Shaoxuan|Oka, Toshinori|Fukushima, Masakazu|Nakagawa, Masayuki|Ono, Mayumi|Kuwano, Michihiko|Akiyama, Shin-ichi
PMID: 18757417
Journal: Bioorg Med Chem. 2008 Oct 1;16(19):9065-78.
Title: Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties.
Author: Ortin, Irene|Gonzalez, Juan Francisco|Cuesta, Elena de la|Manguan-Garcia, Cristina|Perona, Rosario|Avendano, Carmen
PMID: 18799316
Journal: Free Radic Biol Med. 2008 Dec 15;45(12):1642-52.
Title: Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.
Author: Kuwano, Yuki|Tominaga, Kumiko|Kawahara, Tsukasa|Sasaki, Hidekazu|Takeo, Keiko|Nishida, Kensei|Masuda, Kiyoshi|Kawai, Tomoko|Teshima-Kondo, Shigetada|Rokutan, Kazuhito
PMID: 18929641
Journal: J Cell Biol. 2008 Nov 17;183(4):697-710.
Title: RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells.
Author: Ordonez-Moran, Paloma|Larriba, Maria Jesus|Palmer, Hector G|Valero, Ruth A|Barbachano, Antonio|Dunach, Mireia|de Herreros, Antonio Garcia|Villalobos, Carlos|Berciano, Maria Teresa|Lafarga, Miguel|Munoz, Alberto
PMID: 19015318
Journal: Br J Cancer. 2008 Dec 2;99(11):1808-15.
Title: Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells.
Author: Benhadji, K A|Serova, M|Ghoul, A|Cvitkovic, E|Le Tourneau, C|Ogbourne, S M|Lokiec, F|Calvo, F|Hammel, P|Faivre, S|Raymond, E
PMID: 19034280
Journal: Korean J Gastroenterol. 2008 Dec;52(6):359-67.
Title: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa].
Author: Lee, Sang Dae
PMID: 19096253
Journal: J Nutr Biochem. 2009 Feb;20(2):106-14.
Title: Docosahexaenoic acid induces apoptosis in colorectal carcinoma cells by modulating the PI3 kinase and p38 MAPK pathways.
Author: Toit-Kohn, Joe-Lin du|Louw, Louise|Engelbrecht, Anna-Mart
PMID: 18479896
Journal: Cancer Lett. 2009 May 8;277(1):108-13.
Title: p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047.
Author: Adachi, Seiji|Natsume, Hideo|Yamauchi, Junichi|Matsushima-Nishiwaki, Rie|Joe, Andrew K|Moriwaki, Hisataka|Kozawa, Osamu
PMID: 19138820
Journal: Biochem Biophys Res Commun. 2009 May 1;382(2):451-6.
Title: Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells.
Author: Wu, Ya Chun|Wu, William Ka Kei|Li, Youming|Yu, Le|Li, Zhi Jie|Wong, Clover Ching Man|Li, Hai Tao|Sung, Joseph Jao Yiu|Cho, Chi Hin
PMID: 19289106
Journal: Mol Cell Biochem. 2009 Aug;328(1-2):201-8.
Title: MAP kinases in proliferating human colon cancer Caco-2 cells.
Author: Buzzi, Natalia|Colicheo, Andrea|Boland, Ricardo|de Boland, Ana Russo
PMID: 19301097
Journal: Cell Death Differ. 2009 Sep;16(9):1203-14.
Title: p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
Author: Chiacchiera, F|Matrone, A|Ferrari, E|Ingravallo, G|Lo Sasso, G|Murzilli, S|Petruzzelli, M|Salvatore, L|Moschetta, A|Simone, C
PMID: 19343039
Journal: J Pathol. 2009 Aug;218(4):514-9.
Title: Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer.
Author: Gulmann, Christian|Sheehan, Katherine M|Conroy, Ronan M|Wulfkuhle, Julia D|Espina, Virginia|Mullarkey, Michelle J|Kay, Elaine W|Liotta, Lance A|Petricoin, Emanuel F 3rd
PMID: 19396842
Journal: Biomed Environ Sci. 2009 Feb;22(1):76-85.
Title: Potential mechanisms involved in ceramide-induced apoptosis in human colon cancer HT29 cells.
Author: Wang, Jing|Lv, Xiao-Wen|Du, Yu-Guo
PMID: 19462692
Journal: Int J Cancer. 2009 Sep 1;125(5):996-1003.
Title: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
Author: Santoro, Antonietta|Pisanti, Simona|Grimaldi, Claudia|Izzo, Angelo A|Borrelli, Francesca|Proto, Maria C|Malfitano, Anna M|Gazzerro, Patrizia|Laezza, Chiara|Bifulco, Maurizio
PMID: 19479993
Journal: Biochem Pharmacol. 2009 Nov 1;78(9):1205-13.
Title: Macrophage inhibitory cytokine-1 (MIC-1) and subsequent urokinase-type plasminogen activator mediate cell death responses by ribotoxic anisomycin in HCT-116 colon cancer cells.
Author: Yang, Hyun|Choi, Hye Jin|Park, Seong Hwan|Kim, Jong Sik|Moon, Yuseok
PMID: 19540205
Journal: Cancer Prev Res (Phila). 2009 Jul;2(7):650-7.
Title: Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells.
Author: Paul, Shiby|Rimando, Agnes M|Lee, Hong Jin|Ji, Yan|Reddy, Bandaru S|Suh, Nanjoo
PMID: 19549798
Journal: Carcinogenesis. 2009 Sep;30(9):1544-52.
Title: (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Author: Adachi, Seiji|Shimizu, Masahito|Shirakami, Yohei|Yamauchi, Junichi|Natsume, Hideo|Matsushima-Nishiwaki, Rie|To, Satoshi|Weinstein, I Bernard|Moriwaki, Hisataka|Kozawa, Osamu
PMID: 19578043
Journal: Autophagy. 2009 Oct;5(7):1030-3. Epub 2009 Oct 12.
Title: Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism.
Author: Chiacchiera, Fulvio|Simone, Cristiano
PMID: 19587525
Journal: Am J Pathol. 2009 Aug;175(2):557-70.
Title: RETRACTED: Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNFalpha-induced apoptosis in colorectal tumor cells.
Author: Bajbouj, Khuloud|Poehlmann, Angela|Kuester, Doerthe|Drewes, Thomas|Haase, Kathrin|Hartig, Roland|Teller, Anne|Kliche, Stefanie|Walluscheck, Diana|Ivanovska, Jelena|Chakilam, Saritha|Ulitzsch, Annika|Bommhardt, Ursula|Leverkus, Martin|Roessner, Albert|Schn
PMID: 19628771
Journal: Cancer Res. 2009 Aug 15;69(16):6581-9.
Title: Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
Author: Yodkeeree, Supachai|Sung, Bokyung|Limtrakul, Pornngarm|Aggarwal, Bharat B
PMID: 19654295
Journal: Mol Cancer Res. 2009 Aug;7(8):1390-8.
Title: Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha.
Author: Mori, Akira|Moser, Christian|Lang, Sven A|Hackl, Christina|Gottfried, Eva|Kreutz, Marina|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 19671674
Journal: Toxicol Lett. 2009 Dec 15;191(2-3):158-66.
Title: 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
Author: Tikoo, Kulbhushan|Ali, Idrish Yunus|Gupta, Jeena|Gupta, Chanchal
PMID: 19723570
Journal: J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74.
Title: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.
Author: Shan, Jian-zhen|Xuan, Yan-yan|Zheng, Shu|Dong, Qi|Zhang, Su-zhan
PMID: 19735099
Journal: Apoptosis. 2009 Nov;14(11):1266-73.
Title: Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling.
Author: Akimova, Olga A|Lopina, Olga D|Rubtsov, Alexander M|Gekle, Michel|Tremblay, Johanne|Hamet, Pavel|Orlov, Sergei N
PMID: 19784777
Journal: Cancer Res. 2009 Oct 15;69(20):8191-9.
Title: RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects.
Author: Kreeger, Pamela K|Mandhana, Roli|Alford, Shannon K|Haigis, Kevin M|Lauffenburger, Douglas A
PMID: 19789336
Journal: Digestion. 2009;80(4):215-25.
Title: Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer.
Author: Yonezawa, Masaoki|Wada, Ken|Tatsuguchi, Atsushi|Akamatsu, Tomonori|Gudis, Katya|Seo, Tsuguhiko|Mitsui, Keigo|Nagata, Kazuhiro|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu
PMID: 19797898
Journal: Int J Oncol. 2009 Dec;35(6):1499-504.
Title: Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK.
Author: Shin, Dong Yeok|Lee, Won Sup|Lu, Jing Nan|Kang, Myung Hee|Ryu, Chung Ho|Kim, Gi Young|Kang, Ho Sung|Shin, Sung Chul|Choi, Yung Hyun
PMID: 19885574
Journal: Cancer Lett. 2010 Jan 28;287(2):187-95.
Title: Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice.
Author: Wu, Jiann-Ming|Chen, Yun|Chen, Jin-Cherng|Lin, Tzu-Yu|Tseng, Sheng-Hong
PMID: 19586712
Journal: Antioxid Redox Signal. 2010 May 1;12(9):1101-9.
Title: Butyrate-stimulated H2S production in colon cancer cells.
Author: Cao, Qiuhui|Zhang, Li|Yang, Guangdong|Xu, Changqing|Wang, Rui
PMID: 19803745
Journal: Gut. 2010 Mar;59(3):348-56.
Title: CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver.
Author: Kuniyasu, H|Luo, Y|Fujii, K|Sasahira, T|Moriwaka, Y|Tatsumoto, N|Sasaki, T|Yamashita, Y|Ohmori, H
PMID: 19828468
Journal: Biochimie. 2010 Jan;92(1):110-5.
Title: Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells.
Author: Park, Eun Jung|Lim, Jun Hee|Nam, Sung Il|Park, Jong Wook|Kwon, Taeg Kyu
PMID: 19833168
Journal: Cancer Sci. 2010 Jan;101(1):112-9.
Title: CD24-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Author: Wang, Weifei|Wang, Xinying|Peng, Liang|Deng, Qiliang|Liang, Yan|Qing, Haitao|Jiang, Bo
PMID: 19860845
Journal: Apoptosis. 2010 Feb;15(2):183-95.
Title: Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
Author: El-Najjar, Nahed|Chatila, Manal|Moukadem, Hiba|Vuorela, Heikki|Ocker, Matthias|Gandesiri, Muktheshwar|Schneider-Stock, Regine|Gali-Muhtasib, Hala
PMID: 19882352
Journal: J Biol Chem. 2010 Jan 29;285(5):2986-95.
Title: A new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway.
Author: Jang, Eun Ryoung|Ryu, Minsook|Park, Jeong Eun|Kim, Jung-Ho|Lee, Jong-Soo|Song, Kiwon
PMID: 19948725
Journal: Eur J Cancer Prev. 2010 Mar;19(2):153-9.
Title: The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells.
Author: Choi, Kyeong-Hee|Kim, Hyung-Kook|Kim, Jun-Hee|Choi, Eun-Sun|Shin, Ji-Ae|Lee, Syng-Ook|Chintharlapalli, Sudhakar|Safe, Stephen|Abdelrahim, Maen|Kong, Gu|Choi, Hong Seok|Jung, Ji-Youn|Cho, Hyun-Tae|Cho, Nam-Pyo|Cho, Sung-Dae
PMID: 19949342
Journal: Nutr Cancer. 2010;62(1):85-92.
Title: Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells.
Author: Zeng, Huawei|Botnen, James H|Briske-Anderson, Mary
PMID: 20043263
Journal: Mol Cell Endocrinol. 2010 May 14;320(1-2):106-10.
Title: Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta.
Author: Hogan, A M|Collins, D|Sheehan, K|Zierau, O|Baird, A W|Winter, D C
PMID: 20109521
Journal: Eur J Immunol. 2010 Apr;40(4):1011-21.
Title: Targeted inhibition of IL-10-secreting CD25- Treg via p38 MAPK suppression in cancer immunotherapy.
Author: Ohkusu-Tsukada, Kozo|Toda, Masahiro|Udono, Heiichiro|Kawakami, Yutaka|Takahashi, Kimimasa
PMID: 20127675
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G551-62.
Title: Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.
Author: Singh, Pomila|Sarkar, Shubhashish|Umar, Shahid|Rengifo-Cam, William|Singh, Amar P|Wood, Thomas G
PMID: 20133951
Journal: Int J Gynecol Cancer. 2010 Feb;20(2):203-11.
Title: p38alpha is required for ovarian cancer cell metabolism and survival.
Author: Matrone, Antonio|Grossi, Valentina|Chiacchiera, Fulvio|Fina, Emanuela|Cappellari, Marianna|Caringella, Anna Maria|Di Naro, Edoardo|Loverro, Giuseppe|Simone, Cristiano
PMID: 20169663
Journal: Int J Mol Med. 2010 Apr;25(4):635-41.
Title: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.
Author: Kim, Wun-Jae|Lee, Se-Jung|Choi, Young Deuk|Moon, Sung-Kwon
PMID: 20198313
Journal: Int J Oncol. 2010 Apr;36(4):941-53.
Title: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
Author: Lee, Hwa Young|Crawley, Suzanne|Hokari, Ryota|Kwon, Sungwon|Kim, Young S
PMID: 20198339
Journal: J Biol Chem. 2010 May 7;285(19):14617-27.
Title: AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma.
Author: Kim, Min-Jung|Park, In-Ja|Yun, Hee|Kang, Insug|Choe, Wonchae|Kim, Sung-Soo|Ha, Joohun
PMID: 20220132
Journal: Mol Biol Rep. 2010 Dec;37(8):3801-12.
Title: Inhibition of TNFalpha-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-kappaB- and MAPK-dependent mechanisms.
Author: Ruimi, Nili|Petrova, Roumyana D|Agbaria, Riad|Sussan, Sherbel|Wasser, Solomon P|Reznick, Abraham Z|Mahajna, Jamal
PMID: 20224909
Journal: Cell Oncol. 2010 Jan 1;32(4):245-57.
Title: Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.
Author: van Houdt, Winan J|de Bruijn, Menno T|Emmink, Benjamin L|Raats, Danielle|Hoogwater, Frederik J H|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 20413844
Journal: J Cell Biochem. 2010 Jun 1;110(3):581-8.
Title: ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells.
Author: Yang, Min|Yu, Mingcan|Guan, Dongyin|Gu, Jinfa|Cao, Xin|Wang, Weiyun|Zheng, Shu|Xu, Yingying|Shen, Zonghou|Liu, Xinyuan
PMID: 20512919
Journal: Nutr Cancer. 2010;62(5):630-40.
Title: Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK).
Author: Thyagarajan, Anita|Jedinak, Andrej|Nguyen, Hai|Terry, Colin|Baldridge, Lee Ann|Jiang, Jiahua|Sliva, Daniel
PMID: 20574924
Journal: Oncogene. 2010 Sep 16;29(37):5182-92.
Title: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.
Author: Lee, S-H|Bahn, J H|Whitlock, N C|Baek, S J
PMID: 20581861
Journal: Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1527-35.
Title: Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin.
Author: Chen, Wen-Shu|Lee, Yi-Jang|Yu, Yi-Chu|Hsaio, Ching-Hui|Yen, Jui-Hung|Yu, Sz-Hsien|Tsai, Yu-Jia|Chiu, Shu-Jun
PMID: 20637980
Journal: J Clin Biochem Nutr. 2010 Jul;47(1):74-80.
Title: Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway.
Author: Kim, Jun-Hee|Jung, Ji-Youn|Shim, Jung-Hyun|Kim, Jin|Choi, Kyeong-Hee|Shin, Ji-Ae|Choi, Eun-Sun|Lee, Syng-Ook|Chintharlapalli, Sudhakar|Kwon, Ki Han|Leem, Dae-Ho|Cho, Nam-Pyo|Cho, Sung-Dae
PMID: 20664734
Journal: Chem Biol Interact. 2010 Dec 5;188(3):535-45.
Title: Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells.
Author: Liu, Huei-Fang|Hu, Huai-Chin|Chao, Jui-I
PMID: 20708607
Journal: Int J Colorectal Dis. 2010 Dec;25(12):1407-15.
Title: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism.
Author: Jin, Heiying|Tan, Xuanzhong|Liu, Xiufang|Ding, Yijiang
PMID: 20730438
Journal: J Zhejiang Univ Sci B. 2010 Sep;11(9):654-60.
Title: Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules.
Author: He, Wei|Zhang, Mei-fang|Ye, Jun|Jiang, Ting-ting|Fang, Xu|Song, Ying
PMID: 20803769
Journal: Cell Cycle. 2010 Sep 1;9(17):3575-83.
Title: Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAF1/CIP1.
Author: Neise, Denise|Sohn, Dennis|Budach, Wilfried|Janicke, Reiner U
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Journal: IUBMB Life. 2010 Sep;62(9):684-7.
Title: Bisphenol A impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth.
Author: Bolli, Alessandro|Bulzomi, Pamela|Galluzzo, Paola|Acconcia, Filippo|Marino, Maria
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Journal: Zhong Xi Yi Jie He Xue Bao. 2010 Sep;8(9):870-6.
Title: [Tea polyphenol inhibits colorectal cancer with microsatellite instability by regulating the expressions of HES1, JAG1, MT2A and MAFA].
Author: Xu, Yan-Yan|Jin, Hei-Ying|Tan, Xuan-Zhong|Liu, Xiu-Fang|Ding, Yi-Jiang
PMID: 20836978
Journal: Mediators Inflamm. 2010;2010.
Title: The p110alpha and p110beta isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells.
Author: Ivison, Sabine M|Khan, Mohammed A S|Graham, Nicholas R|Shobab, Leila A|Yao, Yu|Kifayet, Arnawaz|Sly, Laura M|Steiner, Theodore S
PMID: 20953381
Journal: PLoS One. 2010 Nov 30;5(11):e14143.
Title: Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers.
Author: Kruewel, Thomas|Schenone, Silvia|Radi, Marco|Maga, Giovanni|Rohrbeck, Astrid|Botta, Maurizio|Borlak, Juergen
PMID: 21152443
Journal: Mol Med Rep. 2010 Mar-Apr;3(2):269-74.
Title: Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation.
Author: Zhou, Hong|Shi, Wenxia|Zhou, Baocheng|Guo, Donglin|Wang, Ting
PMID: 21472232
Journal: Int J Mol Sci. 2010;11(12):4916-31.
Title: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells.
Author: Lee, In Kyung|Kang, Kyoung Ah|Lim, Chae Moon|Kim, Ki Cheon|Kim, Hee Sun|Kim, Dong Hyun|Kim, Bum Joon|Chang, Weon Young|Choi, Jae Hyuck|Hyun, Jin Won
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Journal: Cancer Res. 2011 Feb 1;71(3):1041-9.
Title: Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.
Author: Paillas, Salome|Boissiere, Florence|Bibeau, Frederic|Denouel, Amelie|Mollevi, Caroline|Causse, Annick|Denis, Vincent|Vezzio-Vie, Nadia|Marzi, Laetitia|Cortijo, Cedric|Ait-Arsa, Imade|Askari, Nadav|Pourquier, Philippe|Martineau, Pierre|Del Rio, Maguy|Gongo
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Journal: Cancer Lett. 2011 Feb 28;301(2):193-202.
Title: Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells.
Author: Lepage, C|Leger, D Y|Bertrand, J|Martin, F|Beneytout, J L|Liagre, B
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Journal: J Proteome Res. 2011 Apr 1;10(4):1860-9.
Title: Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response.
Author: Fung, Kim Y C|Brierley, Gemma V|Henderson, Steve|Hoffmann, Peter|McColl, Shaun R|Lockett, Trevor|Head, Richard|Cosgrove, Leah
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Journal: Cancer Res. 2011 Feb 1;71(3):998-1008.
Title: Smad4 inactivation promotes malignancy and drug resistance of colon cancer.
Author: Papageorgis, Panagiotis|Cheng, Kuanghung|Ozturk, Sait|Gong, Yi|Lambert, Arthur W|Abdolmaleky, Hamid M|Zhou, Jin-Rong|Thiagalingam, Sam
PMID: 21245094
Journal: Biochimie. 2011 Apr;93(4):749-57.
Title: HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death.
Author: Limami, Youness|Pinon, Aline|Leger, David Yannick|Mousseau, Yoanne|Cook-Moreau, Jeanne|Beneytout, Jean-Louis|Delage, Christiane|Liagre, Bertrand|Simon, Alain
PMID: 21251952
Journal: Cancer Res. 2011 Feb 15;71(4):1334-43.
Title: Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta.
Author: Al-Mulla, Fahd|Bitar, Milad S|Al-Maghrebi, May|Behbehani, Abdulla I|Al-Ali, Waleed|Rath, Oliver|Doyle, Brendan|Tan, Kit Yee|Pitt, Andrew|Kolch, Walter
PMID: 21303975
Journal: J Periodontal Res. 2011 Apr;46(2):269-79.
Title: Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo.
Author: Guimaraes, M R|Coimbra, L S|de Aquino, S G|Spolidorio, L C|Kirkwood, K L|Rossa, C Jr
PMID: 21306385
Journal: Clin Exp Med. 2011 Dec;11(4):219-26.
Title: Analysis of differentially expressed genes in human rectal carcinoma using suppression subtractive hybridization.
Author: Choi, So-Young|Jang, Jun Hyeog|Kim, Kyung Rae
PMID: 21331762
Journal: Cancer Res. 2011 Mar 1;71(5):1989-98.
Title: LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis.
Author: Hsu, Rich Y C|Chan, Carlos H F|Spicer, Jonathan D|Rousseau, Mathieu C|Giannias, Betty|Rousseau, Simon|Ferri, Lorenzo E
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Journal: Int J Oncol. 2011 Jun;38(6):1695-702.
Title: Inhibition of the p38 MAPK pathway sensitises human colon cancer cells to 5-fluorouracil treatment.
Author: Yang, Shi Yu|Miah, Anur|Sales, Kevin M|Fuller, Barry|Seifalian, Alexander M|Winslet, Marc
PMID: 21424124
Journal: J Biol Chem. 2011 Jun 17;286(24):21577-87.
Title: Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin.
Author: Lee, Won Hyeok|Lee, Hyun Hee|Vo, Mai-Tram|Kim, Hyo Jeong|Ko, Myoung Seok|Im, Yeong-Cheol|Min, Young Joo|Lee, Byung Ju|Cho, Wha Ja|Park, Jeong Woo
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Journal: J Biol Chem. 2011 Jun 17;286(24):21052-61.
Title: Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4.
Author: Shiozaki, Kazuhiro|Yamaguchi, Kazunori|Takahashi, Kohta|Moriya, Setsuko|Miyagi, Taeko
PMID: 21521691
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Mar;33(3):178-82.
Title: [Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms].
Author: Liu, Shi-quan|Qin, Meng-bin|Huang, Jie-an|Zhong, Yue-yuan|Tang, Guo-du|Jiang, Hai-xing
PMID: 21575515
Journal: Anticancer Res. 2011 May;31(5):1607-17.
Title: NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells.
Author: Gochman, Einat|Mahajna, Jamal|Reznick, Abraham Z
PMID: 21617217
Journal: Clin Cancer Res. 2011 Sep 15;17(18):5850-7.
Title: ERK1/2 and p38alpha/beta signaling in tumor cell quiescence: opportunities to control dormant residual disease.
Author: Sosa, Maria Soledad|Avivar-Valderas, Alvaro|Bragado, Paloma|Wen, Huei-Chi|Aguirre-Ghiso, Julio A
PMID: 21673068
Journal: BMC Cancer. 2011 Jul 1;11:285.
Title: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3.
Author: Porquet, Nicolas|Poirier, Andree|Houle, Francois|Pin, Anne-Laure|Gout, Stephanie|Tremblay, Pierre-Luc|Paquet, Eric R|Klinck, Roscoe|Auger, Francois A|Huot, Jacques
PMID: 21722370
Journal: Front Physiol. 2011 Jun 30;2:33.
Title: Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels.
Author: Alzamora, Rodrigo|O'Mahony, Fiona|Ko, Wing-Hung|Yip, Tiffany Wai-Nga|Carter, Derek|Irnaten, Mustapha|Harvey, Brian Joseph
PMID: 21747769
Journal: Ann N Y Acad Sci. 2011 Jul;1229:61-8.
Title: Obesity-induced metabolic stresses in breast and colon cancer.
Author: Sung, Mi-Kyung|Yeon, Jee-Young|Park, Shin-Young|Park, Jung Han Yoon|Choi, Myung-Sook
PMID: 21793840
Journal: Curr Cancer Drug Targets. 2011 Oct;11(8):976-86.
Title: RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors.
Author: Martin, S E|Wu, Z-H|Gehlhaus, K|Jones, T L|Zhang, Y-W|Guha, R|Miyamoto, S|Pommier, Y|Caplen, N J
PMID: 21834757
Journal: Neoplasia. 2011 Aug;13(8):758-70.
Title: Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth.
Author: Gatza, Catherine E|Holtzhausen, Alisha|Kirkbride, Kellye C|Morton, Allyson|Gatza, Michael L|Datto, Michael B|Blobe, Gerard C
PMID: 21847367
Journal: Gastroenterology. 2011 Nov;141(5):1762-72.
Title: Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
Author: Sato, Toshiro|Stange, Daniel E|Ferrante, Marc|Vries, Robert G J|Van Es, Johan H|Van den Brink, Stieneke|Van Houdt, Winan J|Pronk, Apollo|Van Gorp, Joost|Siersema, Peter D|Clevers, Hans
PMID: 21889923
Journal: Int J Mol Epidemiol Genet. 2011;2(4):328-38. Epub 2011 Oct 20.
Title: Tumor necrosis factor-related genes and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Bondurant, Kristina L|Wolff, Roger K
PMID: 22199996
Journal: J Cell Physiol. 2012 Mar;227(3):1114-22.
Title: Stromal cell-derived factor-1/CXC receptor 4 and beta1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells.
Author: Huang, Wen-Shih|Chin, Chih-Chien|Chen, Cheng-Nan|Kuo, Yi-Hung|Chen, Te-Chuan|Yu, Hong-Ren|Tung, Shui-Yi|Shen, Chien-Heng|Hsieh, Yung-Yu|Guo, Su-Er|Shi, Chung-Sheng|Liu, Ta-Ju|Kuo, Hsing-Chun
PMID: 21567400
Journal: Arch Toxicol. 2012 Feb;86(2):329-37.
Title: Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
Author: Donauer, Julia|Schreck, Ilona|Liebel, Urban|Weiss, Carsten
PMID: 21983885
Journal: Br J Pharmacol. 2012 May;166(2):587-601.
Title: Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells.
Author: Minelli, R|Serpe, L|Pettazzoni, P|Minero, V|Barrera, G|Gigliotti, Cl|Mesturini, R|Rosa, A C|Gasco, P|Vivenza, N|Muntoni, E|Fantozzi, R|Dianzani, U|Zara, G P|Dianzani, C
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Journal: Int J Colorectal Dis. 2012 Apr;27(4):437-45.
Title: Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell.
Author: Jia, Zhi-Chao|Wan, Yuan-Lian|Tang, Jian-Qiang|Dai, Yun|Liu, Yu-Cun|Wang, Xin|Zhu, Jing
PMID: 22076613
Journal: Biochim Biophys Acta. 2012 Feb;1820(2):104-15.
Title: Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells.
Author: Hsu, Ya-Fen|Sheu, Joen-Rong|Lin, Chien-Huang|Yang, De-Shin|Hsiao, George|Ou, George|Chiu, Pei-Ting|Huang, Yu-Han|Kuo, Wen-Hsin|Hsu, Ming-Jen
PMID: 22155142
Journal: Nutr Cancer. 2012;64(1):128-35.
Title: Methylselenol, a selenium metabolite, plays common and different roles in cancerous colon HCT116 cell and noncancerous NCM460 colon cell proliferation.
Author: Zeng, Huawei|Briske-Anderson, Mary|Wu, Min|Moyer, Mary P
PMID: 22171558
Journal: Toxicol In Vitro. 2012 Mar;26(2):258-68.
Title: Selenite-induced apoptosis and autophagy in colon cancer cells.
Author: Kralova, Vera|Benesova, Sona|Cervinka, Miroslav|Rudolf, Emil
PMID: 22200533
Journal: Int J Pharm. 2012 May 10;427(2):276-83.
Title: Gemcitabine-releasing polymeric films for covered self-expandable metallic stent in treatment of gastrointestinal cancer.
Author: Lee, Jang Won|Yang, Su-Geun|Na, Kun
PMID: 22366483
Journal: J Cell Physiol. 2012 Nov;227(11):3648-60.
Title: p38alpha MAPK mediates 17beta-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells.
Author: Hsu, Hsi-Hsien|Liu, Chung-Jung|Shen, Chia-Yao|Chen, Yi-Jyun|Chen, Li-Mien|Kuo, Wu-Hsien|Lin, Yueh-Min|Chen, Ray-Jade|Tsai, Chang-Hai|Tsai, Fuu-Jen|Huang, Chih-Yang
PMID: 22377968
Journal: Int J Biochem Cell Biol. 2012 Jun;44(6):896-904.
Title: p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Author: Park, Ji-Young|Song, Ji-Young|Kim, Hyun Mi|Han, Hye-Sook|Seol, Hyang Sook|Jang, Se Jin|Choi, Jene
PMID: 22405851
Journal: Chem Biol Interact. 2012 Apr 15;197(1):1-7.
Title: Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC delta-independent mechanism.
Author: Lim, Jun Hee|Woo, Seon Min|Min, Kyoung-Jin|Park, Eun Jung|Jang, Ji Hoon|Seo, Bo Ram|Iqbal, Taha|Lee, Tae-Jin|Kim, Sang Hyun|Choi, Yung Hyun|Kwon, Taeg Kyu
PMID: 22410117
Journal: Biochimie. 2012 Aug;94(8):1754-63.
Title: The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.
Author: Limami, Youness|Pinon, Aline|Leger, David Yannick|Pinault, Emilie|Delage, Christiane|Beneytout, Jean-Louis|Simon, Alain|Liagre, Bertrand
PMID: 22521508
Journal: J Cell Biochem. 2012 Sep;113(9):2937-47.
Title: Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells.
Author: Goncalves, Pedro|Catarino, Telmo|Gregorio, Ines|Martel, Fatima
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Journal: Expert Opin Investig Drugs. 2012 Jun;21(6):879-89.
Title: Regorafenib for cancer.
Author: Strumberg, Dirk|Schultheis, Beate
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Journal: Cancer Lett. 2012 Nov 1;324(1):98-108.
Title: Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models.
Author: Chiacchiera, Fulvio|Grossi, Valentina|Cappellari, Marianna|Peserico, Alessia|Simonatto, Marta|Germani, Aldo|Russo, Silvana|Moyer, Mary P|Resta, Nicoletta|Murzilli, Stefania|Simone, Cristiano
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Journal: Food Funct. 2012 Aug;3(8):844-52.
Title: Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway.
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Journal: Carcinogenesis. 2012 Jul;33(7):1375-83.
Title: Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model.
Author: Tang, Anliu|Li, Nan|Li, Xiayu|Yang, Hongyuan|Wang, Wei|Zhang, Liyang|Li, Guiyuan|Xiong, Wei|Ma, Jian|Shen, Shourong
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Journal: Free Radic Biol Med. 2012 Aug 1;53(3):532-43.
Title: P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Author: Zhan, Yao|Gong, Ke|Chen, Chao|Wang, Haiqing|Li, Wenhua
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Journal: Autophagy. 2012 Jul 1;8(7):1098-112.
Title: MAPK14/p38alpha confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.
Author: Paillas, Salome|Causse, Annick|Marzi, Laetitia|de Medina, Philippe|Poirot, Marc|Denis, Vincent|Vezzio-Vie, Nadia|Espert, Lucile|Arzouk, Hayat|Coquelle, Arnaud|Martineau, Pierre|Del Rio, Maguy|Pattingre, Sophie|Gongora, Celine
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Journal: Int J Colorectal Dis. 2012 Dec;27(12):1569-78.
Title: Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways.
Author: Liu, Shi-Quan|Huang, Jie-An|Qin, Meng-Bin|Su, Ying-Jie|Lai, Ming-Yu|Jiang, Hai-Xing|Tang, Guo-Du
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Journal: Oncol Rep. 2012 Sep;28(3):931-6.
Title: Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas.
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Journal: Glia. 2012 Oct;60(10):1567-78.
Title: The axon guidance molecule Netrin-4 is expressed by Muller cells and contributes to angiogenesis in the retina.
Author: Lange, Johannes|Yafai, Yousef|Noack, Andre|Yang, Xiu Mei|Munk, Anne-Britta|Krohn, Sandra|Iandiev, Ianors|Wiedemann, Peter|Reichenbach, Andreas|Eichler, Wolfram
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Journal: Surgery. 2012 Aug;152(2):286-93.
Title: Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.
Author: Wakeman, Derek|Schneider, John E|Liu, Jingxia|Wandu, Wambul S|Erwin, Christopher R|Guo, Jun|Stappenbeck, Thaddeus S|Warner, Brad W
PMID: 22828150
Journal: Toxicol Lett. 2012 Oct 2;214(1):1-8.
Title: Irinotecan induces senescence and apoptosis in colonic cells in vitro.
Author: Rudolf, Emil|John, Stanislav|Cervinka, Miroslav
PMID: 22898888
Journal: Cancer Biol Ther. 2012 Dec;13(14):1471-81.
Title: Sorafenib inhibits p38alpha activity in colorectal cancer cells and synergizes with the DFG-in inhibitor SB202190 to increase apoptotic response.
Author: Grossi, Valentina|Liuzzi, Micaela|Murzilli, Stefania|Martelli, Nicola|Napoli, Anna|Ingravallo, Giuseppe|Del Rio, Alberto|Simone, Cristiano
PMID: 22986232
Journal: Carcinogenesis. 2012 Dec;33(12):2398-408.
Title: MAP kinase genes and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Wolff, Roger K
PMID: 23027623
Journal: J Biomed Sci. 2012 Oct 25;19:91.
Title: CXC chemokine ligand 12/stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1.
Author: Tung, Shui-Yi|Chang, Shun-Fu|Chou, Ming-Hui|Huang, Wen-Shih|Hsieh, Yung-Yu|Shen, Chien-Heng|Kuo, Hsing-Chun|Chen, Cheng-Nan
PMID: 23098564
Journal: BMC Cell Biol. 2012 Oct 31;13:27.
Title: Phosphorylation of p68 RNA helicase by p38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin.
Author: Dey, Heena|Liu, Zhi-Ren
PMID: 23110695
Journal: Vasc Cell. 2012 Nov 17;4(1):18.
Title: Regulation of endothelial permeability and transendothelial migration of cancer cells by tropomyosin-1 phosphorylation.
Author: Simoneau, Bryan|Houle, Francois|Huot, Jacques
PMID: 23157718
Journal: PLoS One. 2012;7(11):e49605.
Title: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
Author: Lin, Shih-Pei|Lee, Yi-Ting|Wang, Jir-You|Miller, Stephanie A|Chiou, Shih-Hwa|Hung, Mien-Chie|Hung, Shih-Chieh
PMID: 23185379
Journal: Genes Cancer. 2012 Jul;3(7-8):521-30.
Title: MK2 Regulates Ras Oncogenesis through Stimulating ROS Production.
Author: Kobayashi, Yusuke|Qi, Xiaomei|Chen, Guan
PMID: 23264852
Journal: J Nutr Biochem. 2013 May;24(5):776-80.
Title: Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of colon cancer xenografts in Balb/c mice.
Author: Zeng, Huawei|Cheng, Wen-Hsing|Johnson, Luann K
PMID: 22841391
Journal: Int J Cancer. 2013 Apr 1;132(7):1537-46.
Title: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation.
Author: Groschl, Benedikt|Bettstetter, Marcus|Giedl, Christian|Woenckhaus, Matthias|Edmonston, Tina|Hofstadter, Ferdinand|Dietmaier, Wolfgang
PMID: 22965873
Journal: J Nat Med. 2013 Jul;67(3):468-79.
Title: Synergistic anticancer activities of the plant-derived sesquiterpene lactones salograviolide A and iso-seco-tanapartholide.
Author: Salla, Mohamed|Fakhoury, Isabelle|Saliba, Najat|Darwiche, Nadine|Gali-Muhtasib, Hala
PMID: 22976170
Journal: J Cell Physiol. 2013 May;228(5):1017-24.
Title: Visfatin induces stromal cell-derived factor-1 expression by beta1 integrin signaling in colorectal cancer cells.
Author: Huang, Wen-Shih|Chen, Cheng-Nan|Sze, Chun-I|Teng, Chih-Chuan
PMID: 23042611
Journal: Am J Clin Nutr. 2013 Jan;97(1):117-26.
Title: The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial.
Author: Liu, Zhi-Hua|Huang, Mei-Jin|Zhang, Xing-Wei|Wang, Lei|Huang, Nan-Qi|Peng, Hui|Lan, Pin|Peng, Jun-Sheng|Yang, Zhen|Xia, Yang|Liu, Wei-Jie|Yang, Jun|Qin, Huan-Long|Wang, Jian-Ping
PMID: 23235200
Journal: Biochem Biophys Res Commun. 2013 Jan 25;430(4):1240-5.
Title: p38MAPK and Rho-dependent kinase are involved in anoikis induced by anicequol or 25-hydroxycholesterol in DLD-1 colon cancer cells.
Author: Tanaka, Arowu R|Noguchi, Kohji|Fukazawa, Hidesuke|Igarashi, Yasuhiro|Arai, Hiroyuki|Uehara, Yoshimasa
PMID: 23266613
Journal: Planta Med. 2013 Mar;79(3-4):219-26.
Title: 5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis.
Author: Patil, Jaiprakash R|Jayaprakasha, Guddadarangavvanahally K|Kim, Jinhee|Murthy, Kotamballi N Chidambara|Chetti, Mahadev B|Nam, Sang-Yong|Patil, Bhimanagouda S
PMID: 23345169
Journal: Cancer Sci. 2013 May;104(5):604-10.
Title: Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways.
Author: Zhang, Long|Ji, Qing|Liu, Xuan|Chen, Xingzhu|Chen, Zhaohua|Qiu, Yanyan|Sun, Jian|Cai, Jianfeng|Zhu, Huirong|Li, Qi
PMID: 23363445
Journal: Mutat Res. 2013 Jan-Feb;741-742:27-34.
Title: The role of p38 in irinotecan-induced DNA damage and apoptosis of colon cancer cells.
Author: Rudolf, E|Kralova, V|Rudolf, K|John, S
PMID: 23422270
Journal: PLoS One. 2013;8(2):e56369.
Title: Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling.
Author: Bodur, Cagri|Kutuk, Ozgur|Karsli-Uzunbas, Gizem|Isimjan, Tayirjan T|Harrison, Paul|Basaga, Huveyda
PMID: 23441183
Journal: J Agric Food Chem. 2013 Apr 17;61(15):3631-41.
Title: Inhibitory effects of dried longan (Euphoria longana Lam.) seed extract on invasion and matrix metalloproteinases of colon cancer cells.
Author: Panyathep, Atita|Chewonarin, Teera|Taneyhill, Khanittha|Vinitketkumnuen, Usanee|Surh, Young-Joon
PMID: 23527961
Journal: Biochim Biophys Acta. 2013 Aug;1830(8):4053-64.
Title: Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade.
Author: Chang, Hang-Lung|Chen, Chih-Yu|Hsu, Ya-Fen|Kuo, Wen-Shin|Ou, George|Chiu, Pei-Ting|Huang, Yu-Han|Hsu, Ming-Jen
PMID: 23583370
Journal: Life Sci. 2013 Jun 13;92(22):1081-92.
Title: The synthetic flavonoid WYC02-9 inhibits colorectal cancer cell growth through ROS-mediated activation of MAPK14 pathway.
Author: Chen, Yun-Ju|Chen, Hsin-Pao|Cheng, Yu-Jen|Lin, Yu-Heng|Liu, Kuang-Wen|Chen, Yun-Ju|Hou, Ming-Feng|Wu, Yang-Chang|Lee, Yi-Chen|Yuan, Shyng-Shiou
PMID: 23624232
Journal: J Agric Food Chem. 2013 May 22;61(20):4898-904.
Title: Hericium erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice.
Author: Kim, Sung Phil|Nam, Seok Hyun|Friedman, Mendel
PMID: 23668749
Journal: J Amino Acids. 2013;2013:509056.
Title: DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment.
Author: Gomez-Monterrey, Isabel|Campiglia, Pietro|Scognamiglio, Ilaria|Vanacore, Daniela|Dicitore, Alessandra|Lombardi, Angela|Caraglia, Michele|Novellino, Ettore|Stiuso, Paola
PMID: 23710334
Journal: Int J Oncol. 2013 Aug;43(2):629-37.
Title: Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Author: Chen, Hui-Jye|Lin, Chung-Ming|Lee, Chao-Ying|Shih, Nai-Chen|Amagaya, Sakae|Lin, Yung-Chang|Yang, Jai-Sing
PMID: 23754208
Journal: Int J Oncol. 2013 Aug;43(2):431-8.
Title: Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells.
Author: Shiragami, Risa|Murata, Soichiro|Kosugi, Chihiro|Tezuka, Tohru|Yamazaki, Masato|Hirano, Atsushi|Yoshimura, Yukino|Suzuki, Masato|Shuto, Kiyohiko|Koda, Keiji
PMID: 23754252
Journal: Zhonghua Yi Xue Za Zhi. 2013 Mar 12;93(10):746-50.
Title: [Expression and clinicopathological significance of serine-257/threonine-261 phosphorylated MKK4 in colorectal carcinoma].
Author: Huang, Mei-jin|Wang, Pu-ning|Huang, Jun|Zhang, Xing-wei|Wang, Lei|Liu, Huan-liang|Wang, Jian-ping
PMID: 23755811
Journal: Carcinogenesis. 2013 Oct;34(10):2350-60.
Title: A mechanistic study of the proapoptotic effect of tolfenamic acid: involvement of NF-kappaB activation.
Author: Jeong, Jin Boo|Yang, Xuyu|Clark, Ruth|Choi, Jieun|Baek, Seung Joon|Lee, Seong-Ho
PMID: 23784084
Journal: J Biomed Sci. 2013 Jun 21;20:39.
Title: Flt-1 in colorectal cancer cells is required for the tumor invasive effect of placental growth factor through a p38-MMP9 pathway.
Author: Wei, Shu-Chen|Tsao, Po-Nien|Weng, Meng-Tzu|Cao, Zhifang|Wong, Jau-Min
PMID: 23799978
Journal: Nutr Cancer. 2013;65(5):718-28.
Title: Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.
Author: Cordero-Herrera, Isabel|Martin, Maria Angeles|Bravo, Laura|Goya, Luis|Ramos, Sonia
PMID: 23859040
Journal: Nutr Cancer. 2013;65(5):729-38.
Title: Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Wolff, Roger K
PMID: 23859041
Journal: Anticancer Res. 2013 Aug;33(8):3225-31.
Title: 15,16-Dihydrotanshinone I-induced apoptosis in human colorectal cancer cells: involvement of ATF3.
Author: Suk, Fat-Moon|Jou, Wen-Ju|Lin, Ren-Jye|Lin, Shyr-Yi|Tzeng, Fang-Yu|Liang, Yu-Chih
PMID: 23898083
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2013 May;44(3):393-6, 401.
Title: [Role of p38 mitogen-activated protein kinase pathway in pathogenesis of ulcerative colitis].
Author: He, Fu-Qian|Zou, Yu-Pei|Huang, Xiao-Li|Gao, Feng-Jiao|Peng, Lan|Gan, Hua-Tian
PMID: 23898520
Journal: Int J Oncol. 2013 Oct;43(4):1235-43.
Title: Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways.
Author: Lin, Jiumao|Chen, Youqin|Wei, Lihui|Shen, Aling|Sferra, Thomas J|Hong, Zhenfeng|Peng, Jun
PMID: 23900560
Journal: Oncol Lett. 2013 Jul;6(1):3-8.
Title: A genetic variation of the p38beta promoter region is correlated with an increased risk of sporadic colorectal cancer.
Author: Huang, Qinghua|Chen, Dianke|Song, Shunxin|Fu, Xinhui|Wei, Yisheng|Lu, Jiachun|Wang, Lei|Wang, Jianping
PMID: 23946768
Journal: Mol Cancer Ther. 2013 Oct;12(10):2121-34.
Title: Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.
Author: Mazard, Thibault|Causse, Annick|Simony, Joelle|Leconet, Wilhem|Vezzio-Vie, Nadia|Torro, Adeline|Jarlier, Marta|Evrard, Alexandre|Del Rio, Maguy|Assenat, Eric|Martineau, Pierre|Ychou, Marc|Robert, Bruno|Gongora, Celine
PMID: 23960095
Journal: Oncol Rep. 2013 Dec;30(6):2647-52.
Title: Antitumor effect of 1, 8-cineole against colon cancer.
Author: Murata, Soichiro|Shiragami, Risa|Kosugi, Chihiro|Tezuka, Tohru|Yamazaki, Masato|Hirano, Atsushi|Yoshimura, Yukino|Suzuki, Masato|Shuto, Kiyohiko|Ohkohchi, Nobuhiro|Koda, Keiji
PMID: 24085263
Journal: Cancer Res. 2013 Dec 15;73(24):7232-42.
Title: Functional TLR5 genetic variants affect human colorectal cancer survival.
Author: Klimosch, Sascha N|Forsti, Asta|Eckert, Jana|Knezevic, Jelena|Bevier, Melanie|von Schonfels, Witigo|Heits, Nils|Walter, Jessica|Hinz, Sebastian|Lascorz, Jesus|Hampe, Jochen|Hartl, Dominik|Frick, Julia-Stefanie|Hemminki, Kari|Schafmayer, Clemens|Weber, Ale
PMID: 24154872
Journal: Evid Based Complement Alternat Med. 2013;2013:458075.
Title: A Type II Arabinogalactan from Anoectochilus formosanus for G-CSF Production in Macrophages and Leukopenia Improvement in CT26-Bearing Mice Treated with 5-Fluorouracil.
Author: Yang, Li-Chan|Lu, Ting-Jang|Lin, Wen-Chuan
PMID: 24191166
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E23-35.
Title: IL-32gamma enhances TNF-alpha-induced cell death in colon cancer.
Author: Park, Eun-Seok|Yoo, Jae-Myung|Yoo, Hwan-Soo|Yoon, Do-Young|Yun, Yeo-Pyo|Hong, Jintae
PMID: 23255489
Journal: Endocr Relat Cancer. 2013 Dec 20;21(1):73-84.
Title: GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction.
Author: Huang, Ssu-Ming|Chen, Tzu-Sheng|Chiu, Chien-Ming|Chang, Leang-Kai|Liao, Kuan-Fu|Tan, Hsiao-Ming|Yeh, Wei-Lan|Chang, Gary Ro-Lin|Wang, Min-Ying|Lu, Dah-Yuu
PMID: 24165321
Journal: Cancer Lett. 2014 Mar 1;344(1):110-8.
Title: Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.
Author: Germani, Aldo|Matrone, Antonio|Grossi, Valentina|Peserico, Alessia|Sanese, Paola|Liuzzi, Micaela|Palermo, Rocco|Murzilli, Stefania|Campese, Antonio Francesco|Ingravallo, Giuseppe|Canettieri, Gianluca|Tezil, Tugsan|Simone, Cristiano
PMID: 24215867
Journal: Integr Cancer Ther. 2014 May;13(3):240-8.
Title: Scutellaria Barbata D Don Inhibits Colorectal Cancer Growth via Suppression of Multiple Signaling Pathways.
Author: Lin, Jiumao|Chen, Youqin|Cai, Qiaoyan|Wei, Lihui|Zhan, Youzhi|Shen, Aling|Sferra, Thomas J|Peng, Jun
PMID: 24231788
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36.
Title: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.
Author: Zhang, Jingjing|Dou, Wei|Zhang, Eryun|Sun, Aning|Ding, Lili|Wei, Xiaohui|Chou, Guixin|Mani, Sridhar|Wang, Zhengtao
PMID: 24232001
Journal: Oncol Rep. 2014 Feb;31(2):625-33.
Title: (-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer.
Author: Maruyama, Takehito|Murata, Soichiro|Nakayama, Ken|Sano, Naoki|Ogawa, Koichi|Nowatari, Takeshi|Tamura, Takafumi|Nozaki, Reiji|Fukunaga, Kiyoshi|Ohkohchi, Nobuhiro
PMID: 24337301
Journal: Mol Cancer Res. 2014 Mar;12(3):348-58.
Title: T-type Ca2+ channel inhibition induces p53-dependent cell growth arrest and apoptosis through activation of p38-MAPK in colon cancer cells.
Author: Dziegielewska, Barbara|Brautigan, David L|Larner, James M|Dziegielewski, Jaroslaw
PMID: 24362252
Journal: Mol Pharmacol. 2014 Mar;85(3):451-9.
Title: Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.
Author: Trondl, Robert|Flocke, Lea S|Kowol, Christian R|Heffeter, Petra|Jungwirth, Ute|Mair, Georg E|Steinborn, Ralf|Enyedy, Eva A|Jakupec, Michael A|Berger, Walter|Keppler, Bernhard K
PMID: 24378333
Journal: Int J Oncol. 2014 Mar;44(3):781-90.
Title: S100A6 stimulates proliferation and migration of colorectal carcinoma cells through activation of the MAPK pathways.
Author: Duan, Liang|Wu, Rui|Zou, Zhengyu|Wang, Haiyan|Ye, Liwei|Li, Huan|Yuan, Shimei|Li, Xueru|Zha, He|Sun, Hui|Zhang, Yunyuan|Chen, Xian|Zhou, Lan
PMID: 24378749
Journal: Cell Immunol. 2014 Feb;287(2):74-7.
Title: Interleukin-17F attenuates H2O2-induced cell cycle arrest.
Author: Tong, Zan|Yan, Huichao|Liu, Weihuang
PMID: 24423465
Journal: Chem Biol Interact. 2014 Mar 25;211:36-43.
Title: Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation.
Author: Woo, Seon Min|Min, Kyoung-Jin|Kim, Shin|Park, Jong-Wook|Kim, Dong Eun|Chun, Kyung-Soo|Kim, Young Ho|Lee, Tae-Jin|Kim, Sang Hyun|Choi, Yung Hyun|Chang, Jong-Soo|Kwon, Taeg Kyu
PMID: 24440808
Journal: J Biol Chem. 2014 Mar 7;289(10):6394-403.
Title: The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade.
Author: Zhang, Ruowen|Wang, Yulei|Li, Jingxia|Jin, Honglei|Song, Shaojiang|Huang, Chuanshu
PMID: 24451377
Journal: Int J Mol Med. 2014 Apr;33(4):863-9.
Title: Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner.
Author: Kim, Guen Tae|Lee, Se Hee|Kim, Jong Il|Kim, Young Min
PMID: 24535669
Journal: Ann Surg Oncol. 2014 Jun;21(6):1809-16.
Title: Combined morphologic and molecular classification for predicting lymph node metastasis in early-stage colorectal adenocarcinoma.
Author: Ryu, Han Suk|Kim, Woo Ho|Ahn, Soyeon|Kim, Duck-Woo|Kang, Sung-Bum|Park, Hyo Jin|Park, Young Soo|Lee, Chung Hun|Lee, Hye Seung
PMID: 24562932
Journal: Neoplasia. 2014 Jan;16(1):73-83.
Title: Paradoxically augmented anti-tumorigenic action of proton pump inhibitor and GastrininAPCMin/+ intestinal polyposis model.
Author: Han, Young-Min|Hahm, Ki Baik|Park, Jong-Min|Hong, Sung Pyo|Kim, Eun-Hee
PMID: 24563620
Journal: Mol Cancer. 2014 Mar 6;13:48.
Title: Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation.
Author: Yang, Yang|Cai, Xueting|Yang, Jie|Sun, Xiaoyan|Hu, Chunping|Yan, Zhanpeng|Xu, Xiaojun|Lu, Wuguang|Wang, Xiaoning|Cao, Peng
PMID: 24602443
Journal: Biochem Biophys Res Commun. 2014 Apr 4;446(2):487-92.
Title: Interleukin-1alpha promotes extracellular shedding of syndecan-2 via induction of matrix metalloproteinase-7 expression.
Author: Kwon, Mi-Jung|Hong, Eunkyoung|Choi, Youngsil|Kang, Duk-Hee|Oh, Eok-Soo
PMID: 24613844
Journal: Pharm Biol. 2014 Sep;52(9):1158-65.
Title: Diterpenoid C of Radix Curcumae: an inhibitor of proliferation and inducer of apoptosis in human colon adenocarcinoma cells acting via inhibiting MAPK signaling pathway.
Author: Shen, Yan|Lu, Bin|Zhang, Shuo|Ma, Zhong-Jun
PMID: 24646305
Journal: Cancer Cell. 2014 Apr 14;25(4):484-500.
Title: Dual function of p38alpha MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival.
Author: Gupta, Jalaj|del Barco Barrantes, Ivan|Igea, Ana|Sakellariou, Stratigoula|Pateras, Ioannis S|Gorgoulis, Vassilis G|Nebreda, Angel R
PMID: 24684847
Journal: Cell Rep. 2014 Apr 24;7(2):501-13.
Title: Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation.
Author: Maimon, Avraham|Mogilevsky, Maxim|Shilo, Asaf|Golan-Gerstl, Regina|Obiedat, Akram|Ben-Hur, Vered|Lebenthal-Loinger, Ilana|Stein, Ilan|Reich, Reuven|Beenstock, Jonah|Zehorai, Eldar|Andersen, Claus L|Thorsen, Kasper|Orntoft, Torben F|Davis, Roger J|Davidson
PMID: 24726367
Journal: Tumour Biol. 2014 Jul;35(7):7035-45.
Title: AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells.
Author: Shi, Xiaoming|Wu, Shengchun|Yang, Yongbin|Tang, Lei|Wang, Yuexin|Dong, Junjie|Lu, Bonan|Jiang, Guangwei|Zhao, Wei
PMID: 24752576
Journal: Mol Cell Biol. 2014 Aug;34(15):2857-73.
Title: HuR regulates alternative splicing of the TRA2beta gene in human colon cancer cells under oxidative stress.
Author: Akaike, Yoko|Masuda, Kiyoshi|Kuwano, Yuki|Nishida, Kensei|Kajita, Keisuke|Kurokawa, Ken|Satake, Yuzuru|Shoda, Katsutoshi|Imoto, Issei|Rokutan, Kazuhito
PMID: 24865968
Journal: PLoS One. 2014 Jun 5;9(6):e99257.
Title: Disruption of interleukin-1beta autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Author: Clauzure, Mariangeles|Valdivieso, Angel G|Massip Copiz, Maria M|Schulman, Gustavo|Teiber, Maria Luz|Santa-Coloma, Tomas A
PMID: 24901709
Journal: Food Chem Toxicol. 2014 Sep;71:51-9.
Title: Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author: Do, Minh Truong|Na, MinKyun|Kim, Hyung Gyun|Khanal, Tilak|Choi, Jae Ho|Jin, Sun Woo|Oh, Seok Hoon|Hwang, In Hyun|Chung, Young Chul|Kim, Hee Suk|Jeong, Tae Cheon|Jeong, Hye Gwang
PMID: 24930757
Journal: Oncol Lett. 2014 Jun;7(6):1992-1996.
Title: Sorbitol induces apoptosis of human colorectal cancer cells via p38 MAPK signal transduction.
Author: Lu, Xue|Li, Chun|Wang, Yong-Kun|Jiang, Kun|Gai, Xiao-Dong
PMID: 24932277
Journal: Int J Oncol. 2014 Sep;45(3):995-1010.
Title: Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-kappaB in vitro and in vivo.
Author: Tang, Weiwei|Su, Guangjian|Li, Jieyu|Liao, Jinrong|Chen, Shuping|Huang, Chuanzhong|Liu, Fang|Chen, Qiang|Ye, Yunbin
PMID: 24968890
Journal: Tumour Biol. 2014 Oct;35(10):10487-95.
Title: Phosphorylated p38, a negative prognostic biomarker, complements TNM staging prognostication in colorectal cancer.
Author: Fan, Xin-Juan|Wan, Xiang-Bo|Fu, Xin-Hui|Wu, Pei-Huang|Chen, Dian-Ke|Wang, Pu-Ning|Jiang, Li|Wang, Dao-Hai|Chen, Zhi-Ting|Huang, Yan|Wang, Jian-Ping|Wang, Lei
PMID: 25056534
Journal: World J Gastroenterol. 2014 Aug 7;20(29):9744-58.
Title: p38alpha MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.
Author: Grossi, Valentina|Peserico, Alessia|Tezil, Tugsan|Simone, Cristiano
PMID: 25110412
Journal: Oncol Lett. 2014 Sep;8(3):1093-1095.
Title: Polymorphism of the p38beta gene in patients with colorectal cancer.
Author: Dimberg, Jan|Olsen, Renate Slind|Skarstedt, Marita|Lofgren, Sture|Zar, Niklas|Matussek, Andreas
PMID: 25120664
Journal: Asian Pac J Cancer Prev. 2014;15(15):6321-6.
Title: Activation of JNK/p38 pathway is responsible for alpha-methyl-n-butylshikonin induced mitochondria-dependent apoptosis in SW620 human colorectal cancer cells.
Author: Wang, Hai-Bing|Ma, Xiao-Qiong
PMID: 25124618
Journal: Cancer Lett. 2014 Nov 1;354(1):189-99.
Title: The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo.
Author: Hui, Kaiyan|Yang, Yang|Shi, Kejian|Luo, Hui|Duan, Jing|An, Jiajia|Wu, Pa|Ci, Yali|Shi, Lei|Xu, Caimin
PMID: 25128071
Journal: Front Physiol. 2014 Aug 8;5:293.
Title: NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells.
Author: Kuper, Christoph|Beck, Franz-Xaver|Neuhofer, Wolfgang
PMID: 25152734
Journal: Physiol Rep. 2014 Aug 28;2(8). pii: e12143.
Title: Staurosporine synergistically potentiates the deoxycholate-mediated induction of COX-2 expression.
Author: Saeki, Tohru|Inui, Haruka|Fujioka, Saya|Fukuda, Suguru|Nomura, Ayumi|Nakamura, Yasushi|Park, Eun Young|Sato, Kenji|Kanamoto, Ryuhei
PMID: 25168879
Journal: Cancer Res. 2014 Nov 1;74(21):6150-60.
Title: Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38gamma and p38delta, linking inflammation and cancer in colitis-associated colon cancer.
Author: Del Reino, Paloma|Alsina-Beauchamp, Dayanira|Escos, Alejandra|Cerezo-Guisado, Ma Isabel|Risco, Ana|Aparicio, Noelia|Zur, Rafal|Fernandez-Estevez, Marian|Collantes, Elena|Montans, Jose|Cuenda, Ana
PMID: 25217523
Journal: Acta Biochim Biophys Sin (Shanghai). 2014 Dec;46(12):1049-55.
Title: Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway.
Author: Ren, Hongtao|Zhang, Shuqun|Ma, Hongbing|Wang, Yali|Liu, Di|Wang, Xijing|Wang, Zhongwei
PMID: 25348737
Journal: Oncol Lett. 2014 Dec;8(6):2496-2500.
Title: Inhibition of heat shock protein 27 phosphorylation promotes sensitivity to 5-fluorouracil in colorectal cancer cells.
Author: Matsunaga, Atsushi|Ishii, Yoshiyuki|Tsuruta, Masashi|Okabayashi, Koji|Hasegawa, Hirotoshi|Kitagawa, Yuko
PMID: 25364415
Journal: Oncol Lett. 2014 Dec;8(6):2591-2596.
Title: Garlic-derived compound S-allylmercaptocysteine inhibits cell growth and induces apoptosis via the JNK and p38 pathways in human colorectal carcinoma cells.
Author: Zhang, Yan|Li, Hong-Yan|Zhang, Zhi-Hua|Bian, Hong-Lei|Lin, Gui
PMID: 25364433
Journal: Cell Death Dis. 2014 Nov 6;5:e1510.
Title: Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation.
Author: Kao, C|Chao, A|Tsai, C-L|Chuang, W-C|Huang, W-P|Chen, G-C|Lin, C-Y|Wang, T-H|Wang, H-S|Lai, C-H
PMID: 25375375
Journal: Immunity. 2014 Dec 18;41(6):1052-63.
Title: Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.
Author: Wang, Kepeng|Kim, Min Kyoung|Di Caro, Giuseppe|Wong, Jerry|Shalapour, Shabnam|Wan, Jun|Zhang, Wei|Zhong, Zhenyu|Sanchez-Lopez, Elsa|Wu, Li-Wha|Taniguchi, Koji|Feng, Ying|Fearon, Eric|Grivennikov, Sergei I|Karin, Michael
PMID: 25526314
Journal: Mol Carcinog. 2015 Oct;54(10):1070-85.
Title: Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.
Author: Yaffe, Paul B|Power Coombs, Melanie R|Doucette, Carolyn D|Walsh, Mark|Hoskin, David W
PMID: 24819444
Journal: In Vitro Cell Dev Biol Anim. 2015 Jan;51(1):92-101.
Title: [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.
Author: Ryu, Min Ju|Chung, Ha Sook
PMID: 25148824
Journal: J Cell Mol Med. 2015 Feb;19(2):408-17.
Title: Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737.
Author: Zhang, Chong|Shi, Jing|Mao, Shi-ying|Xu, Ya-si|Zhang, Dan|Feng, Lin-yi|Zhang, Bo|Yan, You-you|Wang, Si-cong|Pan, Jian-ping|Yang, You-ping|Lin, Neng-ming
PMID: 25388762
Journal: J Cell Mol Med. 2015 Feb;19(2):474-84.
Title: Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT-29 cells and umbilical vein endothelial cells, and suppresses murine xenograft tumour growth.
Author: Lai, Kuang-Chi|Hsu, Shu-Chun|Yang, Jai-Sing|Yu, Chien-Chih|Lein, Jin-Cherng|Chung, Jing-Gung
PMID: 25403643
Journal: J Agric Food Chem. 2015 Feb 11;63(5):1540-6.
Title: Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38.
Author: Chen, Ming-Cheng|Lee, Nien-Hung|Hsu, Hsi-Hsien|Ho, Tsung-Jung|Tu, Chuan-Chou|Hsieh, Dennis Jine-Yuan|Lin, Yueh-Min|Chen, Li-Mien|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 25611974
Journal: J Gastroenterol. 2015 Sep;50(9):962-74.
Title: Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model.
Author: Nakagaki, Suguru|Arimura, Yoshiaki|Nagaishi, Kanna|Isshiki, Hiroyuki|Nasuno, Masanao|Watanabe, Shuhei|Idogawa, Masashi|Yamashita, Kentaro|Naishiro, Yasuyoshi|Adachi, Yasushi|Suzuki, Hiromu|Fujimiya, Mineko|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 25680886
Journal: J Steroid Biochem Mol Biol. 2015 May;149:128-37.
Title: ERbeta-dependent neuroglobin up-regulation impairs 17beta-estradiol-induced apoptosis in DLD-1 colon cancer cells upon oxidative stress injury.
Author: Fiocchetti, Marco|Camilli, Giulia|Acconcia, Filippo|Leone, Stefano|Ascenzi, Paolo|Marino, Maria
PMID: 25683270
Journal: Int J Mol Med. 2015 Jun;35(6):1603-9.
Title: Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways.
Author: Ibusuki, Kazunari|Sakiyama, Toshio|Kanmura, Shuji|Maeda, Takuro|Iwashita, Yuji|Nasu, Yuichiro|Sasaki, Fumisato|Taguchi, Hiroki|Hashimoto, Shinichi|Numata, Masatsugu|Uto, Hirofumi|Tsubouchi, Hirohito|Ido, Akio
PMID: 25816245
Journal: Biochem Biophys Res Commun. 2015 May 8;460(3):759-65.
Title: Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells.
Author: Yu, Shunji|Hou, Daisen|Chen, Ping|Zhang, Qi|Lv, Bin|Ma, Yunfang|Liu, Fuchen|Liu, Hui|Song, Evelyn J|Yang, Dongqin|Liu, Jie
PMID: 25817730
Journal: Acta Pharmacol Sin. 2015 Apr;36(4):517-27.
Title: Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
Author: Ma, Yi-ming|Han, Wei|Li, Jia|Hu, Li-hong|Zhou, Yu-bo
PMID: 25832431
Journal: Endocr Relat Cancer. 2015 Jun;22(3):455-64.
Title: Brain-derived neurotrophic factor regulates cell motility in human colon cancer.
Author: Huang, Ssu-Ming|Lin, Chingju|Lin, Hsiao-Yun|Chiu, Chien-Ming|Fang, Chia-Wei|Liao, Kuan-Fu|Chen, Dar-Ren|Yeh, Wei-Lan
PMID: 25876647
Journal: Oncotarget. 2015 Apr 20;6(11):8539-51.
Title: Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors.
Author: Gupta, Jalaj|Igea, Ana|Papaioannou, Marilena|Lopez-Casas, Pedro Pablo|Llonch, Elisabet|Hidalgo, Manuel|Gorgoulis, Vassilis G|Nebreda, Angel R
PMID: 25890501
Journal: Br J Pharmacol. 2015 Aug;172(15):3929-43.
Title: Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway.
Author: Xie, Xin|Zhao, Yu|Ma, Chun-Yan|Xu, Xiao-Ming|Zhang, Yan-Qiu|Wang, Chen-Guang|Jin, Jing|Shen, Xin|Gao, Jin-Lai|Li, Na|Sun, Zhi-Jie|Dong, De-Li
PMID: 25953698
Journal: Tumour Biol. 2015 Sep;36(10):7947-60.
Title: gamma-Synuclein confers both pro-invasive and doxorubicin-mediated pro-apoptotic properties to the colon adenocarcinoma LS 174T cell line.
Author: Goh, Kai-Wey|Say, Yee-How
PMID: 25956278
Journal: Mol Cancer. 2015 Jun 27;14:123.
Title: NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7.
Author: Banskota, Suhrid|Regmi, Sushil C|Kim, Jung-Ae
PMID: 26116564
Journal: Biomol Ther (Seoul). 2015 Jul;23(4):339-44.
Title: Anti-Proliferative Effect of Naringenin through p38-Dependent Downregulation of Cyclin D1 in Human Colorectal Cancer Cells.
Author: Song, Hun Min|Park, Gwang Hun|Eo, Hyun Ji|Lee, Jin Wook|Kim, Mi Kyoung|Lee, Jeong Rak|Lee, Man Hyo|Koo, Jin Suk|Jeong, Jin Boo
PMID: 26157550
Journal: Onco Targets Ther. 2015 Jul 8;8:1691-9.
Title: Screening of potential diagnostic markers and therapeutic targets against colorectal cancer.
Author: Tian, XiaoQing|Sun, DanFeng|Zhao, ShuLiang|Xiong, Hua|Fang, JingYuan
PMID: 26185457
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Mol Med Rep. 2015 Oct;12(4):5816-20.
Title: Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis.
Author: Du, Jie|Chen, Chunyou|Sun, Yiqun|Zheng, Lin|Wang, Wanchen
PMID: 26239027
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19401-18.
Title: Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Author: Lan, Qiusheng|Li, Shoufeng|Lai, Wei|Xu, Heyang|Zhang, Yang|Zeng, Yujie|Lan, Wenjian|Chu, Zhonghua
PMID: 26287184
Journal: EMBO Mol Med. 2015 Oct;7(10):1350-65.
Title: PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Author: Deschoemaeker, Sofie|Di Conza, Giusy|Lilla, Sergio|Martin-Perez, Rosa|Mennerich, Daniela|Boon, Lise|Hendrikx, Stefanie|Maddocks, Oliver D K|Marx, Christian|Radhakrishnan, Praveen|Prenen, Hans|Schneider, Martin|Myllyharju, Johanna|Kietzmann, Thomas|Vousden
PMID: 26290450
Journal: Mol Med Rep. 2015 Oct;12(4):5939-44.
Title: Colchicine induces apoptosis in HT29 human colon cancer cells via the AKT and c-Jun N-terminal kinase signaling pathways.
Author: Huang, Zhen|Xu, Ye|Peng, Wei
PMID: 26299305
Journal: Food Chem Toxicol. 2015 Oct;84:125-32.
Title: Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
Author: Cerezo-Guisado, Maria Isabel|Zur, Rafal|Lorenzo, Maria Jesus|Risco, Ana|Martin-Serrano, Miguel A|Alvarez-Barrientos, Alberto|Cuenda, Ana|Centeno, Francisco
PMID: 26303273
Journal: Int J Mol Sci. 2015 Aug 20;16(8):19851-67.
Title: Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway.
Author: Wang, Juan|Huang, Fengxiang|Bai, Zhun|Chi, Bixia|Wu, Jiacai|Chen, Xu
PMID: 26307972
Journal: Exp Cell Res. 2015 Oct 15;338(1):10-21.
Title: Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells.
Author: Coskun, Deniz|Obakan, Pinar|Arisan, Elif Damla|Coker-Gurkan, Ajda|Palavan-Unsal, Narcin
PMID: 26318418
Journal: Asian Pac J Cancer Prev. 2015;16(14):5835-42.
Title: Melatonin inhibits the Migration of Colon Cancer RKO cells by Down-regulating Myosin Light Chain Kinase Expression through Cross-talk with p38 MAPK.
Author: Zou, Duo-Bing|Wei, Xiao|Hu, Ruo-Lei|Yang, Xiao-Ping|Zuo, Li|Zhang, Su-Mei|Zhu, Hua-Qing|Zhou, Qing|Gui, Shu-Yu|Wang, Yuan
PMID: 26320459
Journal: Mol Cancer Res. 2015 Dec;13(12):1533-43.
Title: Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53.
Author: Song, Xinxin|Dilly, Ashok-Kumar|Choudry, Haroon Asif|Bartlett, David L|Kwon, Yong Tae|Lee, Yong J
PMID: 26354682
Journal: BMC Cancer. 2015 Sep 15;15:638.
Title: Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.
Author: Rastetter, Raphael H|Blomacher, Margit|Drebber, Uta|Marko, Marija|Behrens, Juliane|Solga, Roxana|Hojeili, Sarah|Bhattacharya, Kurchi|Wunderlich, Claudia M|Wunderlich, F Thomas|Odenthal, Margarete|Ziemann, Anja|Eichinger, Ludwig|Clemen, Christoph S
PMID: 26373535
Journal: BMC Complement Altern Med. 2015 Sep 24;15:336.
Title: Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells.
Author: Yim, Nam-Hui|Kim, Aeyung|Jung, Young Pil|Kim, Taesoo|Ma, Choong Je|Ma, Jin Yeul
PMID: 26403976
Journal: Mol Med Rep. 2015 Nov;12(5):7538-44.
Title: Knockdown of biglycan expression by RNA interference inhibits the proliferation and invasion of, and induces apoptosis in, the HCT116 colon cancer cell line.
Author: Xing, Xiaojing|Gu, Xiaohu|Ma, Tianfei
PMID: 26459740
Journal: Mol Med Rep. 2015 Dec;12(6):8062-70.
Title: Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines.
Author: Fang, Feng-Qi|Guo, Hui-Shu|Zhang, Jie|Ban, Li-Ying|Liu, Ji-Wei|Yu, Pei-Yao
PMID: 26498992
Journal: Sci Rep. 2015 Oct 29;5:15900.
Title: The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
Author: Huang, Yu-Han|Huang, Shiu-Wen|Hsu, Ya-Fen|Ou, George|Huang, Wei-Jan|Hsu, Ming-Jen
PMID: 26510776
Journal: Drug Des Devel Ther. 2015 Oct 30;9:5851-62.
Title: Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.
Author: Zhang, Lian|Tong, Yingying|Zhang, Xiuli|Pan, Minggui|Chen, Siyu
PMID: 26586936
Journal: Int J Clin Exp Med. 2015 Sep 15;8(9):14805-15. eCollection 2015.
Title: Anticolorectal cancer effects and pharmacokinetic application of 2, 2-Bis [4-(4-amino-3-hydroxyphenoxy) phenyl] adamantane.
Author: Yang, Po-Sheng|Wang, Jane-Jen|Tsai, Tung-Hu|Wang, Yea-Hwey|Jan, Woan-Ching|Cheng, Shih-Ping|Chi, Chin-Wen|Hsu, Yi-Chiung
PMID: 26628962
Journal: Int J Clin Exp Med. 2015 Sep 15;8(9):15413-22. eCollection 2015.
Title: ROS/p38/p53/Puma signaling pathway is involved in emodin-induced apoptosis of human colorectal cancer cells.
Author: Liu, Baorong|Yuan, Bo|Zhang, Lan|Mu, Weimin|Wang, Chongmin
PMID: 26629030
Journal: Int J Mol Sci. 2015 Dec 29;17(1). pii: ijms17010041.
Title: Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
Author: Ren, Bao-Jun|Zhou, Zhi-Wei|Zhu, Da-Jian|Ju, Yong-Le|Wu, Jin-Hao|Ouyang, Man-Zhao|Chen, Xiao-Wu|Zhou, Shu-Feng
PMID: 26729093
Journal: EBioMedicine. 2015 Dec 15;2(12):1848-9.
Title: PP2A Level in Colorectal Cancer Cells Predicts the Response of p38 Targeted Therapy.
Author: Shang, Chaowei|Huang, Shile
PMID: 26844254
Journal: EBioMedicine. 2015 Nov 19;2(12):1944-56.
Title: PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer.
Author: Zhang, Yanjie|Wang, Xiaowen|Qin, Xiaoyu|Wang, Xinxin|Liu, Feng|White, Eileen|Zheng, X F Steven
PMID: 26844273
Journal: EBioMedicine. 2015 Dec;2(12):1944-1956.
Title: PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer.
Author: Zhang, Yanjie|Wang, Xiaowen|Qin, Xiaoyu|Wang, Xinxin|Liu, Feng|White, Eileen|Zheng, X F Steven
PMID: 28958491
Journal: Gut. 2016 Oct;65(10):1690-701.
Title: New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Author: Qi, Jingjing|Yu, Yong|Akilli Ozturk, Ozlem|Holland, Jane D|Besser, Daniel|Fritzmann, Johannes|Wulf-Goldenberg, Annika|Eckert, Klaus|Fichtner, Iduna|Birchmeier, Walter
PMID: 26156959
Journal: Int J Cancer. 2016 Feb 1;138(3):770-5.
Title: Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
Author: Ray, Anita L|Castillo, Eliseo F|Morris, Katherine T|Nofchissey, Robert A|Weston, Lea L|Samedi, Von G|Hanson, Joshua A|Gaestel, Matthias|Pinchuk, Irina V|Beswick, Ellen J
PMID: 26238259
Journal: Oncogene. 2016 Jun 16;35(24):3190-200.
Title: The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
Author: Rey, C|Faustin, B|Mahouche, I|Ruggieri, R|Brulard, C|Ichas, F|Soubeyran, I|Lartigue, L|De Giorgi, F
PMID: 26522728
Journal: Free Radic Res. 2016;50(1):1-13.
Title: The proteasome inhibitor lactacystin enhances GSH synthesis capacity by increased expression of antioxidant components in an Nrf2-independent, but p38 MAPK-dependent manner in rat colorectal carcinoma cells.
Author: Huseby, Nils-Erik|Ravuri, Chandra|Moens, Ugo
PMID: 26530909
Journal: Oncol Rep. 2016 Feb;35(2):939-47.
Title: BMP9/p38 MAPK is essential for the antiproliferative effect of resveratrol on human colon cancer.
Author: Yuan, Shuang-Xue|Wang, Dong-Xu|Wu, Qiu-Xiang|Ren, Chun-Mei|Li, Yang|Chen, Qian-Zhao|Zeng, Yu-Hua|Shao, Ying|Yang, Jun-Qin|Bai, Yan|Zhang, Pu|Yu, Yu|Wu, Ke|Sun, Wen-Juan|He, Bai-Cheng
PMID: 26555012
Journal: Cancer Res. 2016 Feb 1;76(3):724-35.
Title: Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.
Author: Marusiak, Anna A|Stephenson, Natalie L|Baik, Hayeon|Trotter, Eleanor W|Li, Yaoyong|Blyth, Karen|Mason, Susan|Chapman, Phil|Puto, Lorena A|Read, Jon A|Brassington, Claire|Pollard, Hannah K|Phillips, Chris|Green, Isabelle|Overman, Ross|Collier, Matthew|Test
PMID: 26637668
Journal: J Natl Cancer Inst. 2015 Dec 30;108(6):djv394.
Title: Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.
Author: Santoro, Valeria|Jia, Ruochen|Thompson, Hannah|Nijhuis, Anke|Jeffery, Rosemary|Kiakos, Konstantinos|Silver, Andrew R|Hartley, John A|Hochhauser, Daniel
PMID: 26719345
Journal: Biomol Ther (Seoul). 2016 Mar 1;24(2):140-6.
Title: Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer.
Author: Song, Hun Min|Park, Gwang Hun|Eo, Hyun Ji|Jeong, Jin Boo
PMID: 26797111
Journal: Chin J Integr Med. 2016 Jan 29. pii: 10.1007/s11655-015-2108-3.
Title: Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.
Author: Zhang, Lei-Lei|Si, Jian-Yong|Zhang, Li-Jing|Xiao-Wei, Huo|Lin, Li|Li, Ru-Yi|Chen, Dan|Cao, Li
PMID: 26825081
Journal: Bioorg Med Chem. 2016 Mar 15;24(6):1356-61.
Title: New derivative of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-one (BChTT) elicits antiproliferative effect via p38-mediated cell cycle arrest in cancer cells.
Author: Juszczak, Malgorzata|Walczak, Katarzyna|Matysiak, Joanna|Lemieszek, Marta K|Langner, Ewa|Karpinska, Monika M|Pozarowski, Piotr|Niewiadomy, Andrzej|Rzeski, Wojciech
PMID: 26897091
Journal: Mol Nutr Food Res. 2016 May;60(5):1068-78.
Title: Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization.
Author: Byun, Sanguine|Shin, Seung Ho|Park, Jiman|Lim, Semi|Lee, Eunjung|Lee, Chaeyoon|Sung, Dongeun|Farrand, Lee|Lee, Seoung Rak|Kim, Ki Hyun|Dong, Zigang|Lee, Sam W|Lee, Ki Won
PMID: 26918318
Journal: Oncotarget. 2016 Mar 29;7(13):16840-54.
Title: Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells.
Author: Yue, Wenjie|Lin, Yuli|Yang, Xuguang|Li, Bingji|Liu, Jie|He, Rui
PMID: 26919238
Journal: Proteomics. 2016 May;16(10):1557-69.
Title: Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author: Tai, William Chi-Shing|Wong, Wing-Yan|Lee, Magnolia Muk-Lan|Chan, Brandon Dow|Lu, Cheng|Hsiao, Wen-Luan Wendy
PMID: 26970558
Journal: Oncol Rep. 2016 May;35(5):2691-8.
Title: Oridonin inhibits the proliferation of human colon cancer cells by upregulating BMP7 to activate p38 MAPK.
Author: Ren, Chun-Mei|Li, Yang|Chen, Qian-Zhao|Zeng, Yu-Hua|Shao, Ying|Wu, Qiu-Xiang|Yuan, Shuang-Xue|Yang, Jun-Qin|Yu, Yu|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 26986967
Journal: Mar Drugs. 2016 Mar 29;14(4). pii: md14040069.
Title: In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells.
Author: Eo, Hyun Ji|Kwon, Tae-Hyung|Park, Gwang Hun|Song, Hun Min|Lee, Su-Jin|Park, Nyun-Ho|Jeong, Jin Boo
PMID: 27043582
Journal: J BUON. 2016 Jan-Feb;21(1):87-94.
Title: Arctigenin induces apoptosis in colon cancer cells through ROS/p38MAPK pathway.
Author: Li, Qing-chun|Liang, Yun|Tian, Yuan|Hu, Guang-rui
PMID: 27061535
Journal: Cell Signal. 2016 Aug;28(8):924-36.
Title: c-Myb regulates NOX1/p38 to control survival of colorectal carcinoma cells.
Author: Pekarcikova, Lucie|Knopfova, Lucia|Benes, Petr|Smarda, Jan
PMID: 27107996
Journal: Oncol Rep. 2016 Jun;35(6):3341-8.
Title: Oridonin upregulates PTEN through activating p38 MAPK and inhibits proliferation in human colon cancer cells.
Author: Wu, Qiu-Xiang|Yuan, Shuang-Xue|Ren, Chun-Mei|Yu, Yu|Sun, Wen-Juan|He, Bai-Cheng|Wu, Ke
PMID: 27108927
Journal: J Steroid Biochem Mol Biol. 2016 Oct;163:164-72.
Title: c-Jun NH2-teminal kinase 1 interacts with vitamin D receptor and affects vitamin D-mediated inhibition of cancer cell proliferation.
Author: Bi, Xiuli|Shi, Qi|Zhang, Huijuan|Bao, Yonghua|Hu, Dong|Pohl, Nicole|Fang, Wenfeng|Dong, Huali|Xia, Xichun|Fan, Dongdong|Yang, Wancai
PMID: 27174721
Journal: J Cell Biochem. 2016 Dec;117(12):2875-2885.
Title: Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2 Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells.
Author: Semaan, Josiane|Pinon, Aline|Rioux, Benjamin|Hassan, Lama|Limami, Youness|Pouget, Christelle|Fagnere, Catherine|Sol, Vincent|Diab-Assaf, Mona|Simon, Alain|Liagre, Bertrand
PMID: 27192488
Journal: Cell Death Dis. 2016 May 19;7:e2228.
Title: Knockdown of linc-UFC1 suppresses proliferation and induces apoptosis of colorectal cancer.
Author: Yu, T|Shan, T-D|Li, J-Y|Huang, C-Z|Wang, S-Y|Ouyang, H|Lu, X-J|Xu, J-H|Zhong, W|Chen, Q-K
PMID: 27195675
Journal: Int J Med Sci. 2016 Apr 29;13(5):374-85.
Title: An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer.
Author: Koosha, Sanaz|Alshawsh, Mohammed A|Looi, Chung Yeng|Seyedan, Atefehalsadat|Mohamed, Zahurin
PMID: 27226778
Journal: Oncotarget. 2016 Jul 12;7(28):43442-43460.
Title: Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs.
Author: Barreto, Rafael|Waning, David L|Gao, Hongyu|Liu, Yunlong|Zimmers, Teresa A|Bonetto, Andrea
PMID: 27259276
Journal: Int J Oncol. 2016 Aug;49(2):639-45.
Title: Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Author: Esposito, Giuseppe|Gigli, Stefano|Seguella, Luisa|Nobile, Nicola|D'Alessandro, Alessandra|Pesce, Marcella|Capoccia, Elena|Steardo, Luca|Cirillo, Carla|Cuomo, Rosario|Sarnelli, Giovanni
PMID: 27279570
Journal: J Cancer. 2016 Apr 29;7(8):900-9.
Title: P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer.
Author: He, Jianming|Liang, Xi|Luo, Fen|Chen, Xuedan|Xu, Xueqing|Wang, Fengchao|Zhang, Zhenping
PMID: 27313779
Journal: Int J Oncol. 2016 Sep;49(3):1088-98.
Title: Torilis japonica extract-generated intracellular ROS induces apoptosis by reducing the mitochondrial membrane potential via regulation of the AMPK-p38 MAPK signaling pathway in HCT116 colon cancer.
Author: Kim, Guen Tae|Lee, Se Hee|Kim, Young Min
PMID: 27314881
Journal: Oncotarget. 2016 Jul 19;7(29):45819-45836.
Title: TES inhibits colorectal cancer progression through activation of p38.
Author: Li, Huili|Huang, Kun|Gao, Lu|Wang, Lixia|Niu, Yanfeng|Liu, Hongli|Wang, Zheng|Wang, Lin|Wang, Guobin|Wang, Jiliang
PMID: 27323777
Journal: Oncotarget. 2016 Jul 19;7(29):45837-45848.
Title: Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway.
Author: Xie, Xinyou|Liu, Huixing|Wang, Yanzhong|Zhou, Yanwen|Yu, Haitao|Li, Guiling|Ruan, Zhi|Li, Fengying|Wang, Xiuhong|Zhang, Jun
PMID: 27323852
Journal: Tumour Biol. 2016 Oct;37(10):13225-13235.
Title: Depletion of UBA protein 2-like protein inhibits growth and induces apoptosis of human colorectal carcinoma cells.
Author: Chai, Rui|Yu, Xiaojun|Tu, Shiliang|Zheng, Bo'an
PMID: 27456362
Journal: Oncotarget. 2016 Sep 13;7(37):59766-59780.
Title: Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells.
Author: Goncalves-Ribeiro, Samuel|Diaz-Maroto, Natalia Guillen|Berdiel-Acer, Mireia|Soriano, Antonio|Guardiola, Jordi|Martinez-Villacampa, Mercedes|Salazar, Ramon|Capella, Gabriel|Villanueva, Alberto|Martinez-Balibrea, Eva|Mollevi, David G
PMID: 27517495
Journal: Int J Cancer. 2016 Dec 1;139(11):2553-69.
Title: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.
Author: Xia, Jianling|Huang, Na|Huang, Hongxiang|Sun, Li|Dong, Shaoting|Su, Jinyu|Zhang, Jingwen|Wang, Lin|Lin, Li|Shi, Min|Bin, Jianping|Liao, Yulin|Li, Nailin|Liao, Wangjun
PMID: 27529686
Journal: Tumour Biol. 2016 Oct;37(10):14205-14215.
Title: Decreased expression of LncRNA SLC25A25-AS1 promotes proliferation, chemoresistance, and EMT in colorectal cancer cells.
Author: Li, Yuan|Huang, Shengkai|Li, Yan|Zhang, Weilong|He, Kun|Zhao, Mei|Lin, Hong|Li, Dongdong|Zhang, Honggang|Zheng, Zhaoxu|Huang, Changzhi
PMID: 27553025
Journal: Cell Biol Int. 2016 Dec;40(12):1280-1293.
Title: Gene expression profile analysis of dbpA knockdown in colorectal cancer cells.
Author: Liu, Ruiting|Wang, Guorong|Liu, Chang|Qiu, Jian|Yan, Likun|Li, Xiaojun|Wang, Xiaoqiang
PMID: 27569444
Journal: Br J Cancer. 2016 Nov 8;115(10):1223-1233.
Title: FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.
Author: Marzi, L|Combes, E|Vie, N|Ayrolles-Torro, A|Tosi, D|Desigaud, D|Perez-Gracia, E|Larbouret, C|Montagut, C|Iglesias, M|Jarlier, M|Denis, V|Linares, L K|Lam, E W-F|Martineau, P|Del Rio, M|Gongora, C
PMID: 27685445
Journal: Sci Signal. 2016 Oct 11;9(449):rs11.
Title: Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks.
Author: Simmons, Alan J|Scurrah, Cherie R|McKinley, Eliot T|Herring, Charles A|Irish, Jonathan M|Washington, M Kay|Coffey, Robert J|Lau, Ken S
PMID: 27729552
Journal: Int J Mol Cell Med. 2016 Summer;5(3):178-191. Epub 2016 Aug 30.
Title: Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells.
Author: Shafiee, Gholamreza|Saidijam, Massoud|Tavilani, Heidar|Ghasemkhani, Neda|Khodadadi, Iraj
PMID: 27942504
Journal: Integr Med Res. 2016 Dec;5(4):284-292.
Title: Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells.
Author: Yim, Nam-Hui|Gu, Min Jung|Hwang, Youn-Hwan|Cho, Won-Kyung|Ma, Jin Yeul
PMID: 28462130
Journal: Environ Toxicol. 2017 Aug;32(8):2021-2031.
Title: Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP-2/9 expression via p38 MAPK pathway.
Author: Hsu, Hsi-Hsien|Kuo, Wei-Wen|Day, Cecilia Hsuan|Shibu, Marthandam Asokan|Li, Shin-Yi|Chang, Sheng-Huang|Shih, Hui-Nung|Chen, Ray-Jade|Viswanadha, Vijaya Padma|Kuo, Yueh-Hsiung|Huang, Chih-Yang
PMID: 27807932
Journal: Int J Mol Med. 2017 Jan;39(1):217-222.
Title: SN38 increases IL-8 expression through the MAPK pathways in HCT8 cells.
Author: Zhang, Lei|Lou, Wen-Hui|Xu, Xue-Feng|Wu, Wenchuan|Rong, Ye-Fei|Jin, Da-Yong
PMID: 27878250
Journal: J Cell Biochem. 2017 Jun;118(6):1614-1621.
Title: Characterization of the Pro-Inflammatory Cytokine IL-1beta on Butyrate Oxidation in Colorectal Cancer Cells.
Author: Johnstone, Megan|Bennett, Natalie|Standifer, Cynthia|Smith, Alexis|Han, Anna|Bettaieb, Ahmed|Whelan, Jay|Donohoe, Dallas R
PMID: 27922186
Journal: Oncotarget. 2017 Jan 3;8(1):1678-1687.
Title: p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription.
Author: Zhong, Liang|Simoneau, Bryan|Huot, Jacques|Simard, Martin J
PMID: 27926494
Journal: Biochem J. 2017 Feb 20;474(5):647-665.
Title: Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.
Author: Said, Anan H|Hu, Shien|Abutaleb, Ameer|Watkins, Tonya|Cheng, Kunrong|Chahdi, Ahmed|Kuppusamy, Panjamurthy|Saxena, Neeraj|Xie, Guofeng|Raufman, Jean-Pierre
PMID: 28008134
Journal: FASEB J. 2017 Apr;31(4):1516-1530.
Title: Inflammatory hypoxia induces syndecan-2 expression through IL-1beta-mediated FOXO3a activation in colonic epithelia.
Author: Choi, Sojoong|Chung, Heesung|Hong, Heejeong|Kim, So Yeon|Kim, Seong-Eun|Seoh, Ju-Young|Moon, Chang Mo|Yang, Eun Gyeong|Oh, Eok-Soo
PMID: 28031321
Journal: J Cell Physiol. 2017 Dec;232(12):3444-3453.
Title: Inhibitory effect of blue light emitting diode on migration and invasion of cancer cells.
Author: Oh, Phil-Sun|Kim, Hyun-Soo|Kim, Eun-Mi|Hwang, Hyosook|Ryu, Hyang Hwa|Lim, SeokTae|Sohn, Myung-Hee|Jeong, Hwan-Jeong
PMID: 28098340
Journal: Free Radic Biol Med. 2017 Mar;104:280-297.
Title: CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk.
Author: Chen, Pinjia|Luo, Xiaoyong|Nie, Peipei|Wu, Baoyan|Xu, Wei|Shi, Xinpeng|Chang, Haocai|Li, Bing|Yu, Xiurong|Zou, Zhengzhi
PMID: 28131902
Journal: Oncotarget. 2017 Apr 4;8(14):23603-23612.
Title: The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.
Author: Zheng, Hua-Chuan|Liu, Jia-Jie|Li, Jing|Wu, Ji-Cheng|Yang, Lei|Zhao, Gui-Feng|Zhao, Xin|Jiang, Hua-Mao|Huang, Ke-Qiang|Li, Zhi-Jie
PMID: 28223542
Journal: Curr Med Chem. 2017;24(14):1383-1402.
Title: Emerging Insight into MAPK Inhibitors and Immunotherapy in Colorectal Cancer.
Author: Pancione, Massimo|Giordano, Guido|Parcesepe, Pietro|Cerulo, Luigi|Coppola, Luigi|Curatolo, Anais Del|Conciatori, Fabiana|Milella, Michele|Porras, Almudena
PMID: 28245767
Journal: PLoS One. 2017 Mar 8;12(3):e0172491.
Title: Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.
Author: Weber, Lea|Al-Refae, Klaudia|Ebbert, Juliane|Jagers, Peter|Altmuller, Janine|Becker, Christian|Hahn, Stephan|Gisselmann, Gunter|Hatt, Hanns
PMID: 28273117
Journal: PLoS One. 2017 Mar 29;12(3):e0174591.
Title: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
Author: Nagappan, Arulkumar|Lee, Won Sup|Yun, Jeong Won|Lu, Jing Nan|Chang, Seong-Hwan|Jeong, Jae-Hoon|Kim, Gon Sup|Jung, Jin-Myung|Hong, Soon Chan
PMID: 28355296
Journal: Cell Physiol Biochem. 2017;41(5):1851-1864.
Title: Osteopontin Promotes Cell Migration and Invasion, and Inhibits Apoptosis and Autophagy in Colorectal Cancer by activating the p38 MAPK Signaling Pathway.
Author: Huang, Ren-Hong|Quan, Ying-Jun|Chen, Jin-Hong|Wang, Ting-Feng|Xu, Ming|Ye, Min|Yuan, Hao|Zhang, Chong-Jie|Liu, Xiao-Jian|Min, Zhi-Jun
PMID: 28376477
Journal: Nutr Res Pract. 2017 Apr;11(2):90-96.
Title: Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells.
Author: Cha, Jae Hoon|Kim, Woo Kyoung|Ha, Ae Wha|Kim, Myung Hwan|Chang, Moon Jeong
PMID: 28386381
Journal: Oncotarget. 2017 Mar 14;8(11):18322-18336.
Title: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.
Author: Zheng, Hua-Chuan|He, Hao-Yu|Wu, Ji-Cheng|Li, Jing|Zhao, Shuang|Zhao, Gui-Feng|Jiang, Hua-Mao|Yu, Xue-Wen|Li, Zhi-Jie
PMID: 28407690
Journal: Oncol Lett. 2017 Apr;13(4):2337-2343.
Title: Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis.
Author: Ren, Hai-Peng|Yin, Xiao-Yan|Yu, Hai-Ying|Xiao, Hai-Feng
PMID: 28454400
Journal: Molecules. 2017 May 6;22(5). pii: molecules22050756.
Title: Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice.
Author: Wang, Canhong|Huo, Xiaowei|Gao, Li|Sun, Guibo|Li, Cao
PMID: 28481246
Journal: Anticancer Res. 2017 Jun;37(6):2975-2984.
Title: Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Author: Yun, Seungpil|Han, Yong-Seok|Lee, Jun Hee|Kim, Sangmin|Lee, Sang Hun
PMID: 28551635
Journal: Cell Commun Signal. 2017 Jun 12;15(1):21.
Title: LASP2 suppresses colorectal cancer progression through JNK/p38 MAPK pathway meditated epithelial-mesenchymal transition.
Author: Wang, Bin|Zhang, Lanzhi|Zhao, Liying|Zhou, Rui|Ding, Yanqing|Li, Guoxin|Zhao, Liang
PMID: 28606091
Journal: Int J Oncol. 2017 Sep;51(3):959-966.
Title: Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway.
Author: Park, Sun-Young|Oh, Hyung-Hoon|Park, Young-Lan|Yu, Hyung-Min|Myung, Dae-Seong|Cho, Sung-Bum|Lee, Wan-Sik|Park, Daeho|Joo, Young-Eun
PMID: 28713983
Journal: Oncol Rep. 2017 Sep;38(3):1605-1612.
Title: ANP32A modulates cell growth by regulating p38 and Akt activity in colorectal cancer.
Author: Yan, Wei|Bai, Zhun|Wang, Juan|Li, Xumei|Chi, Bixia|Chen, Xu
PMID: 28731192
Journal: Sci Rep. 2017 Aug 8;7(1):7599.
Title: Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Author: Tang, Hao|Yao, Xiaofang|Yao, Cong|Zhao, Xiaoyan|Zuo, Hua|Li, Zhubo
PMID: 28790461
Journal: PLoS One. 2017 Aug 10;12(8):e0182588.
Title: HspB5 correlates with poor prognosis in colorectal cancer and prompts epithelial-mesenchymal transition through ERK signaling.
Author: Li, Qinghua|Wang, Yanlan|Lai, Yuexing|Xu, Ping|Yang, Zhiwen
PMID: 28796798
Journal: Biochem Biophys Res Commun. 2017 Oct 21;492(3):310-315.
Title: TIF1beta is phosphorylated at serine 473 in colorectal tumor cells through p38 mitogen-activated protein kinase as an oxidative defense mechanism.
Author: Shen, Larina Tzu-Wei|Chou, Han-Yi E|Kato, Mitsuyasu
PMID: 28864417
Journal: J Inorg Biochem. 2017 Dec;177:27-38.
Title: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells.
Author: Dandash, Fatima|Leger, David Yannick|Fidanzi-Dugas, Chloe|Nasri, Soumaya|Bregier, Frederique|Granet, Robert|Karam, Walid|Diab-Assaf, Mona|Sol, Vincent|Liagre, Bertrand
PMID: 28923355
Journal: IUBMB Life. 2017 Dec;69(12):956-961.
Title: High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer.
Author: Yang, Yingchi|Jin, Lan|Zhang, Jinghui|Wang, Jin|Zhao, Xiaomu|Wu, Guocong|Yao, Hongwei|Zhang, Zhongtao
PMID: 29131521
Journal: Mol Med Rep. 2017 Dec;16(6):9383-9392.
Title: Melatonin inhibits colon cancer RKO cell migration by downregulating Rhoassociated protein kinase expression via the p38/MAPK signaling pathway.
Author: Liu, Zhen|Zou, Duobing|Yang, Xiaoping|Xue, Xiaolong|Zuo, Li|Zhou, Qing|Hu, Ruolei|Wang, Yuan
PMID: 29152648
Journal: BMC Complement Altern Med. 2017 Dec 13;17(1):531.
Title: Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways.
Author: Liu, Haojie|Zhou, Ming
PMID: 29237430
Journal: Oncol Lett. 2017 Dec;14(6):7947-7956.
Title: Ampelopsin-induced reactive oxygen species enhance the apoptosis of colon cancer cells by activating endoplasmic reticulum stress-mediated AMPK/MAPK/XAF1 signaling.
Author: Park, Ga Bin|Jeong, Jee-Yeong|Kim, Daejin
PMID: 29250183
Journal: Int J Mol Sci. 2017 Dec 18;18(12). pii: ijms18122748.
Title: Canadine from Corydalis turtschaninovii Stimulates Myoblast Differentiation and Protects against Myotube Atrophy.
Author: Lee, Heyjin|Lee, Sang-Jin|Bae, Gyu-Un|Baek, Nam-In|Ryu, Jae-Ha
PMID: 29258243
Journal: Oncotarget. 2017 Oct 10;8(61):103710-103730.
Title: Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway.
Author: Chocry, Mathieu|Leloup, Ludovic|Kovacic, Herve
PMID: 29262595
Journal: Oncotarget. 2017 Dec 6;8(69):113331-113344.
Title: MAEL contributes to gastric cancer progression by promoting ILKAP degradation.
Author: Zhang, Xing|Ning, Yichong|Xiao, Yuzhong|Duan, Huaxin|Qu, Guifang|Liu, Xin|Du, Yan|Jiang, Dejian|Zhou, Jianlin
PMID: 29371914
Journal: Biomol Ther (Seoul). 2018 May 1;26(3):313-321.
Title: Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway.
Author: Lee, Jun Hee|Yun, Chul Won|Lee, Sang Hun
PMID: 28822989
Journal: FASEB J. 2018 Jan;32(1):289-303.
Title: FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing.
Author: Ang, Zhiwei|Xiong, Ding|Wu, Min|Ding, Jeak Ling
PMID: 28883043
Journal: Oncol Rep. 2018 Jan;39(1):61-70.
Title: Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-alpha-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells.
Author: Wang, Yu|Xia, Chunhui|Lun, Zhiqiang|Lv, Yanxin|Chen, Wei|Li, Tao
PMID: 29115534
Journal: Mol Cell Proteomics. 2018 Apr;17(4):550-564.
Title: Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Author: Basken, Joel|Stuart, Scott A|Kavran, Andrew J|Lee, Thomas|Ebmeier, Christopher C|Old, William M|Ahn, Natalie G
PMID: 29255136
Journal: Biomed Pharmacother. 2018 Mar;99:128-133.
Title: Caspase-3/MAPK pathways as main regulators of the apoptotic effect of the phyto-mediated synthesized silver nanoparticle from dried stem of Eleutherococcus senticosus in human cancer cells.
Author: Kim, Chun Gon|Castro-Aceituno, Veronica|Abbai, Ragavendran|Lee, Hyun A|Simu, Shakina Yesmin|Han, Yaxi|Hurh, Joon|Kim, Yeon-Ju|Yang, Deok Chun
PMID: 29331758
Journal: Curr Mol Pharmacol. 2018;11(3):184-190.
Title: Targeting M3 Muscarinic Receptors for Colon Cancer Therapy.
Author: Felton, Jessica|Hu, Shien|Raufman, Jean-Pierre
PMID: 29357811
Journal: Mol Oncol. 2018 Mar;12(3):391-405.
Title: MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Author: Li, Yixin|Li, Liren|Chen, Miao|Yu, Xinfa|Gu, Zhuoyu|Qiu, Huijuan|Qin, Ge|Long, Qian|Fu, Xiaoyan|Liu, Tianze|Li, Wenbin|Huang, Wenlin|Shi, Dingbo|Kang, Tiebang|Luo, Meihua|Wu, Xiaojun|Deng, Wuguo
PMID: 29360267
Journal: Anticancer Drugs. 2018 Mar;29(3):234-242.
Title: Dioscin inhibits colon cancer cells' growth by reactive oxygen species-mediated mitochondrial dysfunction and p38 and JNK pathways.
Author: Li, Shu|Cheng, Binbin|Hou, Lixin|Huang, Lanwei|Cui, Yongkang|Xu, Duo|Shen, Xiaoping|Li, Shuang
PMID: 29389802
Journal: Sci Rep. 2018 Feb 5;8(1):2334.
Title: p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells.
Author: Zhong, Liang|Huot, Jacques|Simard, Martin J
PMID: 29402939
Journal: Oncol Lett. 2018 Feb;15(2):1949-1954.
Title: Dihydroartemisinin increases apoptosis of colon cancer cells through targeting Janus kinase 2/signal transducer and activator of transcription 3 signaling.
Author: Wang, Dongsheng|Zhong, Bei|Li, Yu|Liu, Xiaodong
PMID: 29434895
Journal: Saudi J Gastroenterol. 2018 Jan-Feb;24(1):37-45.
Title: The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors.
Author: Przybyla, Tomasz|Wesserling, Martyna|Sakowicz-Burkiewicz, Monika|Maciejewska, Izabela|Pawelczyk, Tadeusz
PMID: 29451183
Journal: Oncol Lett. 2018 Mar;15(3):3971-3976.
Title: TGFBR1*6A is a potential modifier of migration and invasion in colorectal cancer cells.
Author: Zhou, Rui|Huang, Ying|Cheng, Boran|Wang, Yulei|Xiong, Bin
PMID: 29467907
Journal: Int Immunopharmacol. 2018 Apr;57:82-90.
Title: Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-kappaB and MAPK signalling pathways.
Author: Gao, Zhenfang|Yu, Cuicui|Liang, Haiyue|Wang, Xuekai|Liu, Yue|Li, Xin|Ji, Kai|Xu, Hui|Yang, Mingyan|Liu, Ke|Qi, Dong|Fan, Huaying
PMID: 29475099
Journal: Biomed Pharmacother. 2018 Aug;104:832-840.
Title: MiR-422a targets MAPKK6 and regulates cell growth and apoptosis in colorectal cancer cells.
Author: Li, Peng|Li, Qingmin|Zhang, Yanqiang|Sun, Shaojun|Liu, Shuntao|Lu, Zhaoxi
PMID: 29566993
Journal: Mol Carcinog. 2018 Aug;57(8):1017-1029.
Title: PKCalpha in colon cancer cells promotes M1 macrophage polarization via MKK3/6-P38 MAPK pathway.
Author: Cheng, Yang|Zhu, Yun|Xu, Wanfu|Xu, Jiajia|Yang, Min|Chen, Peiyu|Zhao, Junhong|Geng, Lanlan|Gong, Sitang
PMID: 29637628
Journal: Exp Mol Med. 2018 Apr 13;50(4):21.
Title: Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis.
Author: Zhang, Yong|Wang, Xiao-Lan|Zhou, Min|Kang, Chao|Lang, He-Dong|Chen, Meng-Ting|Hui, Suo-Cheng|Wang, Bin|Mi, Man-Tian
PMID: 29650970
Journal: Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4236-E4244.
Title: MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
Author: Suarez-Lopez, Lucia|Sriram, Ganapathy|Kong, Yi Wen|Morandell, Sandra|Merrick, Karl A|Hernandez, Yuliana|Haigis, Kevin M|Yaffe, Michael B
PMID: 29666270
Journal: Eur Rev Med Pharmacol Sci. 2018 Apr;22(7):1922-1928.
Title: Peroxiredoxin1 promotes cell proliferation, migration and invasion of colorectal cancer via p38MAPK signaling.
Author: Cong, N|Huang, W|Yuan, J-P|Li, G-Z|Zhai, G-S|Li, B-S
PMID: 29687844
Journal: Oncol Lett. 2018 May;15(5):6873-6880.
Title: Simultaneous stimulation with tumor necrosis factor-alpha and transforming growth factor-beta1 induces epithelial-mesenchymal transition in colon cancer cells via the NF-kappaB pathway.
Author: Li, Yuanfei|Zhu, Guoqiang|Zhai, Huihong|Jia, Junmei|Yang, Wenhui|Li, Xiaoqing|Liu, Lixin
PMID: 29725419
Journal: Oncol Lett. 2018 May;15(5):7716-7724.
Title: Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-kappaB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.
Author: Juan, Ta-Kuo|Liu, Kuo-Ching|Kuo, Chao-Lin|Yang, Mei-Due|Chu, Yung-Lin|Yang, Jiun-Long|Wu, Ping-Ping|Huang, Yi-Ping|Lai, Kuang-Chi|Chung, Jing-Gung
PMID: 29731901
Journal: Oncotarget. 2018 Jan 8;9(28):20089-20102.
Title: Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence.
Author: Dou, Jie|Wang, Zhou|Ma, Leon|Peng, Bo|Mao, Ke|Li, Chengqin|Su, Mengqi|Zhou, Changlin|Peng, Guangyong
PMID: 29732005
Journal: Int J Oncol. 2018 Aug;53(2):750-760.
Title: Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs.
Author: Su, Meng-Qi|Zhou, Yi-Ran|Rao, Xuan|Yang, Hong|Zhuang, Xin-Hao|Ke, Xue-Jia|Peng, Guang-Yong|Zhou, Chang-Lin|Shen, Bai-Yong|Dou, Jie
PMID: 29749481
Journal: Redox Biol. 2018 Jul;17:348-354.
Title: Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells.
Author: Serra, Gessica|Incani, Alessandra|Serreli, Gabriele|Porru, Laura|Melis, M Paola|Tuberoso, Carlo I G|Rossin, Daniela|Biasi, Fiorella|Deiana, Monica
PMID: 29793168
Journal: Phytother Res. 2018 Jun 7.
Title: Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells.
Author: Kim, Dong Hee|Shin, Eun Ah|Kim, Bonglee|Shim, Bum Sang|Kim, Sung-Hoon
PMID: 29876988
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20;38(5):511-519.
Title: [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Author: Ai, Xiao-Lan|Yao, Fang|Wang, Xiao-Jing|Duan, Dong-Bei|Li, Ke|Hu, Zi-You|Yin, Guo|Wang, Mei|Wu, Bing-Yi
PMID: 29891445
Journal: EMBO Mol Med. 2018 Jul;10(7). pii: emmm.201708403.
Title: Myeloid p38alpha signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.
Author: Youssif, Catrin|Cubillos-Rojas, Monica|Comalada, Monica|Llonch, Elisabeth|Perna, Cristian|Djouder, Nabil|Nebreda, Angel R
PMID: 29907597
Journal: Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3779-3788.
Title: Study on the function and mechanism of long non-coding RNA DMTF1v4 in the occurrence of colon cancer.
Author: Zhuang, S-T|Cai, Y-J|Gao, H-C|Qiu, J-F|Zeng, L|Zheng, W-J
PMID: 29949153
Journal: Oncol Lett. 2018 Aug;16(2):2326-2334.
Title: MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling.
Author: You, Qi|Li, Huining|Liu, Yao|Xu, Yangyang|Miao, Susheng|Yao, Guodong|Xue, Yingwei|Geng, Jingshu|Jin, Xiaoming|Meng, Hongxue
PMID: 30008936
Journal: Int J Oncol. 2018 Oct;53(4):1469-1480.
Title: Upregulation of PDL1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300mediated NFkappaB signaling.
Author: Lucas, Justin|Hsieh, Tze-Chen|Halicka, H Dorota|Darzynkiewicz, Zbigniew|Wu, Joseph M
PMID: 30066852
Journal: Int J Oncol. 2018 Nov;53(5):2091-2101.
Title: Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.
Author: Liu, Rong-Xing|Ma, Yan|Hu, Xue-Lian|Ren, Wen-Yan|Liao, Yun-Peng|Wang, Han|Zhu, Jia-Hui|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 30132514
Journal: Expert Rev Gastroenterol Hepatol. 2018 Sep 26:1-18.
Title: An update on dietary consideration in inflammatory bowel disease: anthocyanins and more.
Author: Farzaei, Mohammad Hosein|El-Senduny, Fardous F|Momtaz, Saeideh|Parvizi, Fatemeh|Iranpanah, Amin|Tewari, Devesh|Naseri, Rozita|Abdolghaffari, Amir Hossein|Rezaei, Nima
PMID: 30136591
Journal: Front Pharmacol. 2018 Aug 29;9:986.
Title: Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells.
Author: Kee, Ji-Ye|Han, Yo-Han|Mun, Jeong-Geon|Park, Seong-Hwan|Jeon, Hee D|Hong, Seung-Heon
PMID: 30210348
Journal: J Agric Food Chem. 2018 Sep 26;66(38):9960-9967.
Title: Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells.
Author: Choi, Jhin-Baek|Kim, Ju-Ha|Lee, Hyemin|Pak, Ji-Na|Shim, Bum Sang|Kim, Sung-Hoon
PMID: 30211553
Journal: Oncol Lett. 2018 Oct;16(4):4526-4536.
Title: Sequential treatment with celecoxib and bortezomib enhances the ER stress-mediated autophagy-associated cell death of colon cancer cells.
Author: Park, Ga-Bin|Jin, Dong-Hoon|Kim, Daejin
PMID: 30214587
Journal: Int J Oncol. 2018 Sep 14.
Title: Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer.
Author: Kim, Se-Lim|Min, In Suk|Park, Young Ran|Lee, Soo Teik|Kim, Sang-Wook
PMID: 30221676
Journal: Arch Virol. 2018 Sep 26. pii: 10.1007/s00705-018-4026-0.
Title: Suppression of angiogenesis and tumor growth by recombinant T4 phages displaying extracellular domain of vascular endothelial growth factor receptor 2.
Author: Zuo, Shuguang|Dai, Gongpeng|Wang, Liping|Wen, Yuqing|Huang, Zhiang|Yang, Wenyi|Ma, Wanli|Ren, Xuequn
PMID: 30259141
Journal: Arch Med Res. 2018 Oct 9. pii: S0188-4409(18)30568-X.
Title: Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line.
Author: Nafees, Sana|Mehdi, Syed Hassan|Zafaryab, Mohammad|Zeya, Bushra|Sarwar, Tarique|Rizvi, Moshahid Alam
PMID: 30314650
Journal: Mol Cancer Ther. 2018 Oct 18. pii: 1535-7163.MCT-18-0104.
Title: A Unique Non-Saccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.
Author: Boothello, Rio S|Patel, Nirmita J|Sharon, Chetna|Abdelfadiel, Elsamani I|Morla, Shravan|Brophy, Donald F|Lippman, H Robert|Desai, Umesh R|Patel, Bhaumik B
PMID: 30337351
Journal: Cancer Genomics Proteomics. 2018 Nov-Dec;15(6):485-497.
Title: NOTUM Is Involved in the Progression of Colorectal Cancer.
Author: Yoon, Jong Hyuk|Kim, Dayea|Kim, Jaeyoon|Lee, Hyeongjoo|Ghim, Jaewang|Kang, Byung Jun|Song, Parkyong|Suh, Pann-Ghill|Ryu, Sung Ho|Lee, Taehoon G
PMID: 30343282
Journal: J Sci Food Agric. 2018 Oct 24.
Title: Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells.
Author: Shin, Min-Kyoung|Jeon, Yong-Deok|Jin, Jong-Sik
PMID: 30357838