Primary Site >> Colorectal Cancer
Gene >> MAPK14
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Ref: ErbB kinases and NDF signaling in human prostate cancer cells. PMID: 9400997 |
Ref: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. PMID: 9622070 |
Ref: Involvement of p38 MAP kinase in apoptotic and proliferative alteration in human colorectal cancers. PMID: 10697550 |
Ref: Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways. PMID: 10766192 Ref: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice. PMID: 10815928 Ref: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways. PMID: 10866999 Ref: Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades. PMID: 11085935 |
Ref: PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics. PMID: 11156952 Ref: Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis. PMID: 11159738 Ref: Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. PMID: 11159881 Ref: NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps. PMID: 11314016 Ref: Epithelial cyclooxygenase-2 expression: a model for pathogenesis of colon cancer. PMID: 11319881 Ref: Alterations of MAPK activities associated with intestinal cell differentiation. PMID: 11394874 Ref: Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells. PMID: 11459290 Ref: DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells. PMID: 11494044 Ref: Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells. PMID: 11781819 Ref: Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway. PMID: 11806247 |
Ref: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. PMID: 11910351 Ref: Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. PMID: 11980910 Ref: Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism. PMID: 12058282 Ref: Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kappa B. PMID: 12077118 Ref: Up-regulation of Hsp27 plays a role in the resistance of human colon carcinoma HT29 cells to photooxidative stress. PMID: 12126313 Ref: Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells. PMID: 12203364 Ref: Human gastrin-releasing peptide receptor mediates sustained CREB phosphorylation and transactivation in HuTu 80 duodenal cancer cells. PMID: 12220644 Ref: Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation. PMID: 12383707 Ref: The role of mitogen-activated protein kinases and their relationship with NF-kappaB and PPARgamma in indomethacin-Induced apoptosis of colon cancer cells. PMID: 12485869 |
Ref: Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases. PMID: 12618885 Ref: Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids. PMID: 12802055 Ref: The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells. PMID: 12819185 Ref: Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression. PMID: 12824923 Ref: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. PMID: 12839952 Ref: MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2. PMID: 14511767 Ref: Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL. PMID: 14551511 Ref: Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine. PMID: 14556662 Ref: Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling. PMID: 14695170 |
Ref: The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway. PMID: 14729633 Ref: Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells. PMID: 14743399 Ref: Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death. PMID: 14749540 Ref: Flavaglines: a group of efficient growth inhibitors block cell cycle progression and induce apoptosis in colorectal cancer cells. PMID: 15027128 Ref: p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. PMID: 15037631 Ref: The nucleocytoplasmic shuttling of E2F4 is involved in the regulation of human intestinal epithelial cell proliferation and differentiation. PMID: 15040009 Ref: Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. PMID: 15063780 Ref: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells. PMID: 15256484 Ref: Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-g PMID: 15289320 Ref: Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells. PMID: 15298620 Ref: Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway. PMID: 15314290 Ref: Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4. PMID: 15387376 Ref: Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals. PMID: 15548175 |
Ref: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK. PMID: 15611081 Ref: Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. PMID: 15657353 Ref: Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation. PMID: 15735687 Ref: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade. PMID: 15774489 Ref: Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: roles of cyclic AMP and p38 mitogen-activated protein kinase. PMID: 15849811 Ref: Essential role of p38gamma in K-Ras transformation independent of phosphorylation. PMID: 15851477 Ref: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells. PMID: 15860507 Ref: The MAPK signalling pathways and colorectal cancer. PMID: 15863380 Ref: Sulindac sulfide-induced apoptosis in sinonasal cancer cells. PMID: 15880954 Ref: Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells. PMID: 15918186 Ref: Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling. PMID: 15946948 Ref: Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells. PMID: 15951156 Ref: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway. PMID: 15956247 Ref: The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11'-dideoxyverticillin-induced G2/M arrest. PMID: 15963507 Ref: The novel gene EG-1 stimulates cellular proliferation. PMID: 16024617 Ref: Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines. PMID: 16030096 Ref: Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity. PMID: 16033843 Ref: Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily. PMID: 16127155 Ref: Photodynamic therapy-induced death of HCT 116 cells: Apoptosis with or without Bax expression. PMID: 16215676 |
Ref: Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways. PMID: 16169610 Ref: Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation. PMID: 16169935 Ref: p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1. PMID: 16170570 Ref: Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited. PMID: 16263703 Ref: Up-regulation of cyclooxygenase-2 by interleukin-1beta in colon carcinoma cells. PMID: 16326073 Ref: TAK1-mediated stress signaling pathways are essential for TNF-alpha-promoted pulmonary metastasis of murine colon cancer cells. PMID: 16385569 Ref: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. PMID: 16529829 Ref: Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. PMID: 16597643 Ref: Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis. PMID: 16677802 Ref: Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway. PMID: 16697692 Ref: Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases. PMID: 16715142 Ref: Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism. PMID: 16849586 Ref: Death receptor-3, a new E-Selectin counter-receptor that confers migration and survival advantages to colon carcinoma cells by triggering p38 and ERK MAPK activation. PMID: 16982754 Ref: P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin. PMID: 17056038 Ref: Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer. PMID: 17090686 |
Ref: A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells. PMID: 17159917 Ref: Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway. PMID: 17273739 Ref: p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells. PMID: 17308107 Ref: Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts. PMID: 17332478 Ref: Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1. PMID: 17342315 Ref: Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. PMID: 17395984 Ref: Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells. PMID: 17406816 Ref: Signal-dependent control of autophagy and cell death in colorectal cancer cell: the role of the p38 pathway. PMID: 17495519 Ref: Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation. PMID: 17505786 Ref: 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling. PMID: 17513605 Ref: 17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells. PMID: 17524358 Ref: Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. PMID: 17540426 Ref: [The role of p38 MAPK in gastrin-induced u-PA expression in human colon cancer cells]. PMID: 17575684 Ref: Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein. PMID: 17620438 Ref: Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. PMID: 17635998 Ref: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation. PMID: 17640974 Ref: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts. PMID: 17640979 Ref: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B. PMID: 17671195 Ref: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. PMID: 17673978 Ref: Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth. PMID: 17699719 Ref: Thermal sensitization through ROS modulation: a strategy to improve the efficacy of hyperthermic intraperitoneal chemotherapy. PMID: 17723891 Ref: Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. PMID: 17727817 |
Ref: Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. PMID: 17657594 Ref: Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine. PMID: 17941093 Ref: Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells. PMID: 18024214 Ref: Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29). PMID: 18084318 Ref: A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells. PMID: 18093981 Ref: Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells. PMID: 18175946 Ref: Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38. PMID: 18340113 Ref: Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors. PMID: 18395970 Ref: Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells. PMID: 18413805 Ref: Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein. PMID: 18444174 Ref: PEITC induces G1 cell cycle arrest on HT-29 cells through the activation of p38 MAPK signaling pathway. PMID: 18473178 Ref: Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells. PMID: 18499365 Ref: Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells. PMID: 18504038 Ref: Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells. PMID: 18520051 Ref: The FVIIa-tissue factor complex induces the expression of MMP7 in LOVO cells in vitro. PMID: 18548257 Ref: Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. PMID: 18596194 Ref: Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells. PMID: 18671966 Ref: Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells. PMID: 18705300 Ref: Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil. PMID: 18757417 Ref: Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties. PMID: 18799316 Ref: Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. PMID: 18929641 Ref: RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells. PMID: 19015318 Ref: Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. PMID: 19034280 Ref: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa]. PMID: 19096253 |
Ref: Docosahexaenoic acid induces apoptosis in colorectal carcinoma cells by modulating the PI3 kinase and p38 MAPK pathways. PMID: 18479896 Ref: p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047. PMID: 19138820 Ref: Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells. PMID: 19289106 Ref: MAP kinases in proliferating human colon cancer Caco-2 cells. PMID: 19301097 Ref: p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. PMID: 19343039 Ref: Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer. PMID: 19396842 Ref: Potential mechanisms involved in ceramide-induced apoptosis in human colon cancer HT29 cells. PMID: 19462692 Ref: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon. PMID: 19479993 Ref: Macrophage inhibitory cytokine-1 (MIC-1) and subsequent urokinase-type plasminogen activator mediate cell death responses by ribotoxic anisomycin in HCT-116 colon cancer cells. PMID: 19540205 Ref: Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells. PMID: 19549798 Ref: (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells. PMID: 19578043 Ref: Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism. PMID: 19587525 Ref: RETRACTED: Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNFalpha-induced apoptosis in colorectal tumor cells. PMID: 19628771 Ref: Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species. PMID: 19654295 Ref: Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. PMID: 19671674 Ref: 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats. PMID: 19723570 Ref: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway. PMID: 19735099 Ref: Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling. PMID: 19784777 Ref: RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects. PMID: 19789336 Ref: Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer. PMID: 19797898 Ref: Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK. PMID: 19885574 |
Ref: Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. PMID: 19586712 Ref: Butyrate-stimulated H2S production in colon cancer cells. PMID: 19803745 Ref: CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver. PMID: 19828468 Ref: Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells. PMID: 19833168 Ref: CD24-dependent MAPK pathway activation is required for colorectal cancer cell proliferation. PMID: 19860845 Ref: Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling. PMID: 19882352 Ref: A new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway. PMID: 19948725 Ref: The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells. PMID: 19949342 Ref: Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells. PMID: 20043263 Ref: Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta. PMID: 20109521 Ref: Targeted inhibition of IL-10-secreting CD25- Treg via p38 MAPK suppression in cancer immunotherapy. PMID: 20127675 Ref: Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK. PMID: 20133951 Ref: p38alpha is required for ovarian cancer cell metabolism and survival. PMID: 20169663 Ref: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation. PMID: 20198313 Ref: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway. PMID: 20198339 Ref: AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma. PMID: 20220132 Ref: Inhibition of TNFalpha-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-kappaB- and MAPK-dependent mechanisms. PMID: 20224909 Ref: Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition. PMID: 20413844 Ref: ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells. PMID: 20512919 Ref: Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK). PMID: 20574924 Ref: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. PMID: 20581861 Ref: Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin. PMID: 20637980 Ref: Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway. PMID: 20664734 Ref: Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells. PMID: 20708607 Ref: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism. PMID: 20730438 Ref: Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules. PMID: 20803769 Ref: Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAF1/CIP1. PMID: 20818156 Ref: Bisphenol A impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth. PMID: 20836126 Ref: [Tea polyphenol inhibits colorectal cancer with microsatellite instability by regulating the expressions of HES1, JAG1, MT2A and MAFA]. PMID: 20836978 Ref: The p110alpha and p110beta isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells. PMID: 20953381 Ref: Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers. PMID: 21152443 Ref: Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation. PMID: 21472232 Ref: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells. PMID: 21614182 |
Ref: Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma. PMID: 21159664 Ref: Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells. PMID: 21195543 Ref: Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response. PMID: 21235278 Ref: Smad4 inactivation promotes malignancy and drug resistance of colon cancer. PMID: 21245094 Ref: HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death. PMID: 21251952 Ref: Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta. PMID: 21303975 Ref: Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo. PMID: 21306385 Ref: Analysis of differentially expressed genes in human rectal carcinoma using suppression subtractive hybridization. PMID: 21331762 Ref: LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. PMID: 21363926 Ref: Inhibition of the p38 MAPK pathway sensitises human colon cancer cells to 5-fluorouracil treatment. PMID: 21424124 Ref: Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. PMID: 21507959 Ref: Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4. PMID: 21521691 Ref: [Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms]. PMID: 21575515 Ref: NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells. PMID: 21617217 Ref: ERK1/2 and p38alpha/beta signaling in tumor cell quiescence: opportunities to control dormant residual disease. PMID: 21673068 Ref: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3. PMID: 21722370 Ref: Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels. PMID: 21747769 Ref: Obesity-induced metabolic stresses in breast and colon cancer. PMID: 21793840 Ref: RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors. PMID: 21834757 Ref: Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth. PMID: 21847367 Ref: Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. PMID: 21889923 Ref: Tumor necrosis factor-related genes and colon and rectal cancer. PMID: 22199996 |
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