Primary Site >> Biliary tract Cancer
Gene >> MAPK1
| 1. | |||||||||||
| Journal: | Hepatology. 1999 Nov;30(5):1128-33. | ||||||||||
| Title: | Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line. | ||||||||||
| Author: | Park, J|Tadlock, L|Gores, G J|Patel, T | ||||||||||
| PMID: | 10534331 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 2001 Jan;33(1):43-51. | ||||||||||
| Title: | Involvement of p38 mitogen-activated protein kinase signaling in transformed growth of a cholangiocarcinoma cell line. | ||||||||||
| Author: | Tadlock, L|Patel, T | ||||||||||
| PMID: | 11124819 | ||||||||||
| 3. | |||||||||||
| Journal: | Hepatology. 2002 Aug;36(2):363-73. | ||||||||||
| Title: | Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells. | ||||||||||
| Author: | Wu, Tong|Han, Chang|Lunz, John G 3rd|Michalopoulos, George|Shelhamer, James H|Demetris, A Jake | ||||||||||
| PMID: | 12143044 | ||||||||||
| 4. | |||||||||||
| Journal: | Gastroenterology. 2002 Apr;122(4):985-93. | ||||||||||
| Title: | Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. | ||||||||||
| Author: | Yoon, Jung-Hwan|Higuchi, Hajime|Werneburg, Nathan W|Kaufmann, Scott H|Gores, Gregory J | ||||||||||
| PMID: | 11910351 | ||||||||||
| 5. | |||||||||||
| Journal: | Gut. 2003 May;52(5):706-12. | ||||||||||
| Title: | Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. | ||||||||||
| Author: | Tannapfel, A|Sommerer, F|Benicke, M|Katalinic, A|Uhlmann, D|Witzigmann, H|Hauss, J|Wittekind, C | ||||||||||
| PMID: | 12692057 | ||||||||||
| 6. | |||||||||||
| Journal: | Hepatology. 2003 May;37(5):1122-9. | ||||||||||
| Title: | Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma. | ||||||||||
| Author: | Tanaka, Shinji|Sugimachi, Keishi|Kameyama, Toshifumi|Maehara, Shin-Ichiro|Shirabe, Ken|Shimada, Mitsuo|Wands, Jack R|Maehara, Yoshihiko | ||||||||||
| PMID: | 12717393 | ||||||||||
| 7. | |||||||||||
| Journal: | Hepatology. 2004 Mar;39(3):732-8. | ||||||||||
| Title: | Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. | ||||||||||
| Author: | Yoon, Jung-Hwan|Canbay, Ali E|Werneburg, Nathan W|Lee, Sum P|Gores, Gregory J | ||||||||||
| PMID: | 14999691 | ||||||||||
| 8. | |||||||||||
| Journal: | J Clin Invest. 2006 Jul;116(7):1843-52. Epub 2006 Jun 8. | ||||||||||
| Title: | Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. | ||||||||||
| Author: | Xu, Xiaoling|Kobayashi, Shogo|Qiao, Wenhui|Li, Cuiling|Xiao, Cuiying|Radaeva, Svetlana|Stiles, Bangyan|Wang, Rui-Hong|Ohara, Nobuya|Yoshino, Tadashi|LeRoith, Derek|Torbenson, Michael S|Gores, Gregory J|Wu, Hong|Gao, Bin|Deng, Chu-Xia | ||||||||||
| PMID: | 16767220 | ||||||||||
| 9. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2006 Dec;132(12):805-10. Epub 2006 Jun 23. | ||||||||||
| Title: | Expression of phosphorylated ERK1/2 and homeodomain protein CDX2 in cholangiocarcinoma. | ||||||||||
| Author: | Jinawath, Artit|Akiyama, Yoshimitsu|Yuasa, Yasuhito|Pairojkul, Chawalit | ||||||||||
| PMID: | 16794828 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Ther. 2006 Jul;5(7):1895-903. | ||||||||||
| Title: | Assessment of gefitinib- and CI-1040-mediated changes in epidermal growth factor receptor signaling in HuCCT-1 human cholangiocarcinoma by serial fine needle aspiration. | ||||||||||
| Author: | Hidalgo, Manuel|Amador, Maria Luz|Jimeno, Antonio|Mezzadra, Heather|Patel, Pina|Chan, Audrey|Nielsen, Matthew E|Maitra, Anirban|Altiok, Soner | ||||||||||
| PMID: | 16891476 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cell Biochem. 2007 Nov;305(1-2):19-26. Epub 2007 Jun 6. | ||||||||||
| Title: | Prostaglandin E2 enhances mitogen-activated protein kinase/Erk pathway in human cholangiocarcinoma cells: involvement of EP1 receptor, calcium and EGF receptors signaling. | ||||||||||
| Author: | Zhang, Li|Jiang, Li|Sun, Qiuyan|Peng, Tao|Lou, Kexin|Liu, Ningbo|Leng, Jing | ||||||||||
| PMID: | 17551669 | ||||||||||
| 12. | |||||||||||
| Journal: | Hepatogastroenterology. 2007 Jul-Aug;54(77):1339-44. | ||||||||||
| Title: | Intestinal trefoil factor (TFF-3) and extracellular signal-regulated kinase (ERK) in cholangiocarcinoma. | ||||||||||
| Author: | Ailawadhi, Sikander|Nagase, Hiroki|Khoury, Thaer|Yu, Jihnhee|Tan, Dongfeng|Black, Jennifer|Brattain, Michael|Javle, Milind | ||||||||||
| PMID: | 17708250 | ||||||||||
| 13. | |||||||||||
| Journal: | World J Gastroenterol. 2007 Dec 28;13(48):6470-7. | ||||||||||
| Title: | AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Schmitz, K J|Lang, H|Wohlschlaeger, J|Sotiropoulos, G C|Reis, H|Schmid, K W|Baba, H A | ||||||||||
| PMID: | 18161916 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncol Rep. 2008 Oct;20(4):863-72. | ||||||||||
| Title: | The growth inhibition of hepatocellular and cholangiocellular carcinoma cells by gemcitabine and the roles of extracellular signal-regulated and checkpoint kinases. | ||||||||||
| Author: | Matsumoto, Kazuya|Nagahara, Takakazu|Okano, Jun-Ichi|Murawaki, Yoshikazu | ||||||||||
| PMID: | 18813828 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Cancer Res. 2009 Oct;7(10):1704-13. | ||||||||||
| Title: | H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo. | ||||||||||
| Author: | Francis, Heather|Onori, Paolo|Gaudio, Eugenio|Franchitto, Antonio|DeMorrow, Sharon|Venter, Julie|Kopriva, Shelley|Carpino, Guido|Mancinelli, Romina|White, Mellanie|Meng, Fanyin|Vetuschi, Antonella|Sferra, Roberta|Alpini, Gianfranco | ||||||||||
| PMID: | 19825989 | ||||||||||
| 16. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2009 May 18;28:65. | ||||||||||
| Title: | Expression of phospho-ERK1/2 and PI3-K in benign and malignant gallbladder lesions and its clinical and pathological correlations. | ||||||||||
| Author: | Li, Qinglong|Yang, Zhulin | ||||||||||
| PMID: | 19445727 | ||||||||||
| 17. | |||||||||||
| Journal: | Dig Dis Sci. 2010 Oct;55(10):2844-52. | ||||||||||
| Title: | The role of MAPK-ERK pathway in 67-kDa laminin receptor-induced FasL expression in human cholangiocarcinoma cells. | ||||||||||
| Author: | Duan, Shi-Gang|Cheng, Long|Li, Da-Jiang|Zhu, Jin|Xiong, Yan|Li, Xiao-Wu|Wang, Shu-Guang | ||||||||||
| PMID: | 20101459 | ||||||||||
| 18. | |||||||||||
| Journal: | World J Gastroenterol. 2010 Feb 14;16(6):713-22. | ||||||||||
| Title: | Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion. | ||||||||||
| Author: | Menakongka, Apaporn|Suthiphongchai, Tuangporn | ||||||||||
| PMID: | 20135719 | ||||||||||
| 19. | |||||||||||
| Journal: | Hepatogastroenterology. 2010 May-Jun;57(99-100):426-9. | ||||||||||
| Title: | Effective treatment of advanced cholangiocarcinoma by hepatic arterial infusion chemotherapy combination with sorafenib: one case report from China. | ||||||||||
| Author: | Qun, Wang|Tao, Yin | ||||||||||
| PMID: | 20698202 | ||||||||||
| 20. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2011 Mar;18(2):147-53. | ||||||||||
| Title: | Protease-activated receptor-2 regulates cyclooxygenase-2 expression in human bile duct cancer via the pathways of mitogen-activated protein kinases and nuclear factor kappa B. | ||||||||||
| Author: | Eguchi, Hidetoshi|Iwaki, Kentaro|Shibata, Kohei|Ogawa, Tadashi|Ohta, Masayuki|Kitano, Seigo | ||||||||||
| PMID: | 20740367 | ||||||||||
| 21. | |||||||||||
| Journal: | J Gastroenterol. 2011 May;46(5):664-75. | ||||||||||
| Title: | Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases. | ||||||||||
| Author: | Namwat, N|Puetkasichonpasutha, J|Loilome, W|Yongvanit, P|Techasen, A|Puapairoj, A|Sripa, B|Tassaneeyakul, W|Khuntikeo, N|Wongkham, S | ||||||||||
| PMID: | 21076843 | ||||||||||
| 22. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2011 Feb 18;405(3):333-7. | ||||||||||
| Title: | Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2. | ||||||||||
| Author: | Yoon, Hyunho|Min, Jeong-Ki|Lee, Jung Whoi|Kim, Dae-Ghon|Hong, Hyo Jeong | ||||||||||
| PMID: | 21130731 | ||||||||||
| 23. | |||||||||||
| Journal: | Invest New Drugs. 2012 Aug;30(4):1646-51. | ||||||||||
| Title: | SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma. | ||||||||||
| Author: | El-Khoueiry, Anthony B|Rankin, Cathryn J|Ben-Josef, Edgar|Lenz, Heinz-Josef|Gold, Philip J|Hamilton, R Darryl|Govindarajan, Rangaswamy|Eng, Cathy|Blanke, Charles D | ||||||||||
| PMID: | 21748296 | ||||||||||
| 24. | |||||||||||
| Journal: | Hepatology. 2012 Dec;56(6):2268-76. | ||||||||||
| Title: | A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. | ||||||||||
| Author: | Liu, Wangta|Chen, Jim-Ray|Hsu, Chih-Hao|Li, Yen-Hsing|Chen, Yi-Meng|Lin, Chien-Yuan|Huang, Shin-Jie|Chang, Zen-Kuei|Chen, Yen-Chun|Lin, Chi-Hsueh|Gong, Hong-Yi|Lin, Ching-Chun|Kawakami, Koichi|Wu, Jen-Leih | ||||||||||
| PMID: | 22729936 | ||||||||||
| 25. | |||||||||||
| Journal: | Anticancer Res. 2012 Dec;32(12):5251-62. | ||||||||||
| Title: | Gefitinib and gemcitabine coordinately inhibited the proliferation of cholangiocarcinoma cells. | ||||||||||
| Author: | Nakajima, Yoshimi|Takagi, Hitoshi|Kakizaki, Satoru|Horiguchi, Norio|Sato, Ken|Sunaga, Noriaki|Mori, Masatomo | ||||||||||
| PMID: | 23225424 | ||||||||||
| 26. | |||||||||||
| Journal: | ISRN Hepatol. 2013 Nov 17;2013:601071. | ||||||||||
| Title: | Protective Effects of Guava Pulp on Cholestatic Liver Injury. | ||||||||||
| Author: | Peng, Jian|Yue, Chunyan|Qiu, Kai|Chen, Jie|Aller, Maria-Angeles|Ko, Kwang Suk|Yang, Heping | ||||||||||
| PMID: | 27335829 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncol Lett. 2013 Nov;6(5):1439-1446. | ||||||||||
| Title: | CD24 induces the invasion of cholangiocarcinoma cells by upregulating CXCR4 and increasing the phosphorylation of ERK1/2. | ||||||||||
| Author: | Leelawat, Kawin|Keeratichamroen, Siriporn|Leelawat, Surang|Tohtong, Rutaiwan | ||||||||||
| PMID: | 24179538 | ||||||||||
| 28. | |||||||||||
| Journal: | Hepatology. 2013 Jun;57(6):2248-60. | ||||||||||
| Title: | Activation of mammalian target of rapamycin complex 1 (mTORC1) and Raf/Pyk2 by growth factor-mediated Eph receptor 2 (EphA2) is required for cholangiocarcinoma growth and metastasis. | ||||||||||
| Author: | Cui, Xiang-Dan|Lee, Mi-Jin|Kim, Jong-Hyun|Hao, Pei-Pei|Liu, Lan|Yu, Goung-Ran|Kim, Dae-Ghon | ||||||||||
| PMID: | 23315987 | ||||||||||
| 29. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Jan 1;19(1):118-27. | ||||||||||
| Title: | Sequence dependence of MEK inhibitor AZD6244 combined with gemcitabine for the treatment of biliary cancer. | ||||||||||
| Author: | Xu, Junyao|Knox, Jennifer J|Ibrahimov, Emin|Chen, Eric|Serra, Stefano|Tsao, Ming|Cao, Pinjiang|Vines, Douglass|Green, David E|Metran-Nascente, Cristiane|McNamara, Mairead G|Hedley, David W | ||||||||||
| PMID: | 23091117 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Oncol. 2013 Feb;42(2):690-8. | ||||||||||
| Title: | Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma. | ||||||||||
| Author: | Yang, Wei|Wang, Xiaoyuan|Zheng, Wei|Li, Kedong|Liu, Haofeng|Sun, Yueming | ||||||||||
| PMID: | 23254774 | ||||||||||
| 31. | |||||||||||
| Journal: | Biochimie. 2014 Jun;101:183-91. | ||||||||||
| Title: | Mycoepoxydiene induces apoptosis and inhibits TPA-induced invasion in human cholangiocarcinoma cells via blocking NF-kappaB pathway. | ||||||||||
| Author: | Li, Wenjiao|Li, Ming|Su, Xinhui|Qin, Liping|Miao, Mengmeng|Yu, Chundong|Shen, Yuemao|Luo, Qi|Chen, Qiang | ||||||||||
| PMID: | 24486723 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Biol Ther. 2014 Jun 1;15(6):806-14. | ||||||||||
| Title: | MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway. | ||||||||||
| Author: | Wu, Xiang-Song|Wang, Xu-An|Wu, Wen-Guang|Hu, Yun-Ping|Li, Mao-Lan|Ding, Qian|Weng, Hao|Shu, Yi-Jun|Liu, Tian-Yu|Jiang, Lin|Cao, Yang|Bao, Run-Fa|Mu, Jia-Sheng|Tan, Zhu-Jun|Tao, Feng|Liu, Ying-Bin | ||||||||||
| PMID: | 24658096 | ||||||||||
| 33. | |||||||||||
| Journal: | Hepatology. 2014 Sep;60(3):908-18. | ||||||||||
| Title: | Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2. | ||||||||||
| Author: | Liu, Runping|Zhao, Renping|Zhou, Xiqiao|Liang, Xiuyin|Campbell, Deanna J W|Zhang, Xiaoxuan|Zhang, Luyong|Shi, Ruihua|Wang, Guangji|Pandak, William M|Sirica, Alphonse E|Hylemon, Phillip B|Zhou, Huiping | ||||||||||
| PMID: | 24700501 | ||||||||||
| 34. | |||||||||||
| Journal: | Tumour Biol. 2015 Mar;36(3):1781-9. | ||||||||||
| Title: | Up-regulation of 14-3-3zeta expression in intrahepatic cholangiocarcinoma and its clinical implications. | ||||||||||
| Author: | Zhang, Chi|Liu, Li-Xin|Dong, Zhao-Ru|Shi, Guo-Ming|Cai, Jia-Bin|Zhang, Peng-Fei|Ke, Ai-Wu|Yu, Jing-Xian|Zhou, Jian|Fan, Jia | ||||||||||
| PMID: | 25391422 | ||||||||||
| 35. | |||||||||||
| Journal: | Tumour Biol. 2015 Jul;36(7):5171-7. | ||||||||||
| Title: | Loss of angiotensin-converting enzyme 2 promotes growth of gallbladder cancer. | ||||||||||
| Author: | Zong, Huajie|Yin, Baobing|Zhou, Huading|Cai, Duan|Ma, Baojin|Xiang, Yang | ||||||||||
| PMID: | 25663464 | ||||||||||
| 36. | |||||||||||
| Journal: | Int J Oncol. 2015;46(6):2317-26. | ||||||||||
| Title: | Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway. | ||||||||||
| Author: | Amonyingcharoen, Sumet|Suriyo, Tawit|Thiantanawat, Apinya|Watcharasit, Piyajit|Satayavivad, Jutamaad | ||||||||||
| PMID: | 25815516 | ||||||||||
| 37. | |||||||||||
| Journal: | BMC Cancer. 2015 Nov 16;15:903. | ||||||||||
| Title: | Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44nu is an indicator for recurrence in advanced cancer. | ||||||||||
| Author: | Wu, Cheng-Lin|Chao, Ying-Jui|Yang, Ta-Ming|Chen, Yi-Ling|Chang, Kung-Chao|Hsu, Hui-Ping|Shan, Yan-Shen|Lai, Ming-Derg | ||||||||||
| PMID: | 26572077 | ||||||||||
| 38. | |||||||||||
| Journal: | BMC Cancer. 2016 Mar 19;16:240. | ||||||||||
| Title: | TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway. | ||||||||||
| Author: | Hong, HaiJie|Jiang, Lei|Lin, YanFei|He, CaiLong|Zhu, GuangWei|Du, Qiang|Wang, XiaoQian|She, FeiFei|Chen, YanLing | ||||||||||
| PMID: | 26992854 | ||||||||||
| 39. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 8;7(45):72833-72844. | ||||||||||
| Title: | Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway. | ||||||||||
| Author: | Shen, Sheng|Liu, Han|Wang, Yueqi|Wang, Jiwen|Ni, Xiaolin|Ai, Zhilong|Pan, Hongtao|Liu, Houbao|Shao, Yebo | ||||||||||
| PMID: | 27637083 | ||||||||||
| 40. | |||||||||||
| Journal: | PLoS One. 2016 Sep 14;11(9):e0162594. | ||||||||||
| Title: | Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation. | ||||||||||
| Author: | Hall, Terence G|Yu, Yi|Eathiraj, Sudharshan|Wang, Yunxia|Savage, Ronald E|Lapierre, Jean-Marc|Schwartz, Brian|Abbadessa, Giovanni | ||||||||||
| PMID: | 27627808 | ||||||||||
| 41. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2016 Apr 16;35:68. | ||||||||||
| Title: | Prohibitin overexpression predicts poor prognosis and promotes cell proliferation and invasion through ERK pathway activation in gallbladder cancer. | ||||||||||
| Author: | Cao, Yang|Liang, Haibin|Zhang, Fei|Luan, Zhou|Zhao, Shuai|Wang, Xu-An|Liu, Shibo|Bao, Runfa|Shu, Yijun|Ma, Qiang|Zhu, Jian|Liu, Yingbin | ||||||||||
| PMID: | 27084680 | ||||||||||
| 42. | |||||||||||
| Journal: | Mol Med Rep. 2016 May;13(5):4461-8. | ||||||||||
| Title: | Artemisinin inhibits gallbladder cancer cell lines through triggering cell cycle arrest and apoptosis. | ||||||||||
| Author: | Jia, Jianguang|Qin, Yiyu|Zhang, Ligong|Guo, Chenxu|Wang, Yaguo|Yue, Xicheng|Qian, Jun | ||||||||||
| PMID: | 27035431 | ||||||||||
| 43. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Feb 14;22(6):2071-80. | ||||||||||
| Title: | Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice. | ||||||||||
| Author: | Ding, Ning|Che, Li|Li, Xiao-Lei|Liu, Yan|Jiang, Li-Jie|Fan, Biao|Tao, Jun-Yan|Chen, Xin|Ji, Jia-Fu | ||||||||||
| PMID: | 26877611 | ||||||||||
| 44. | |||||||||||
| Journal: | Tumour Biol. 2016 Jul;37(7):9451-63. | ||||||||||
| Title: | YKL-40/chitinase-3-like protein 1 is associated with poor prognosis and promotes cell growth and migration of cholangiocarcinoma. | ||||||||||
| Author: | Thongsom, Sunisa|Chaocharoen, Wethaka|Silsirivanit, Atit|Wongkham, Sopit|Sripa, Banchob|Choe, Han|Suginta, Wipa|Talabnin, Chutima | ||||||||||
| PMID: | 26781979 | ||||||||||
| 45. | |||||||||||
| Journal: | Gut Liver. 2016 Mar;10(2):310-7. | ||||||||||
| Title: | Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells. | ||||||||||
| Author: | Lee, Jin|Hong, Eun Mi|Jang, Ju Ah|Park, Se Woo|Koh, Dong Hee|Choi, Min Ho|Jang, Hyun Joo|Kae, Sea Hyub | ||||||||||
| PMID: | 26470769 | ||||||||||
| 46. | |||||||||||
| Journal: | Gut. 2016 Mar;65(3):487-501. | ||||||||||
| Title: | TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro. | ||||||||||
| Author: | Reich, Maria|Deutschmann, Kathleen|Sommerfeld, Annika|Klindt, Caroline|Kluge, Stefanie|Kubitz, Ralf|Ullmer, Christoph|Knoefel, Wolfram T|Herebian, Diran|Mayatepek, Ertan|Haussinger, Dieter|Keitel, Verena | ||||||||||
| PMID: | 26420419 | ||||||||||
| 47. | |||||||||||
| Journal: | Oncotarget. 2017 Feb 28;8(9):15775-15788. | ||||||||||
| Title: | Stathmin decreases cholangiocarcinoma cell line sensitivity to staurosporine-triggered apoptosis via the induction of ERK and Akt signaling. | ||||||||||
| Author: | Wang, Yueqi|Gao, Zhihui|Zhang, Dexiang|Bo, Xiaobo|Wang, Yaojie|Wang, Jiwen|Shen, Sheng|Liu, Han|Suo, Tao|Pan, Hongtao|Ai, Zhilong|Liu, Houbao | ||||||||||
| PMID: | 28178656 | ||||||||||
| 48. | |||||||||||
| Journal: | Pathol Res Pract. 2017 May;213(5):476-482. | ||||||||||
| Title: | The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer. | ||||||||||
| Author: | Buchegger, Kurt|Silva, Ramon|Lopez, Jaime|Ili, Carmen|Araya, Juan Carlos|Leal, Pamela|Brebi, Priscilla|Riquelme, Ismael|Roa, Juan Carlos | ||||||||||
| PMID: | 28285962 | ||||||||||
| 49. | |||||||||||
| Journal: | Cancer Lett. 2017 Sep 10;403:66-73. | ||||||||||
| Title: | Claudin-18 coupled with EGFR/ERK signaling contributes to the malignant potentials of bile duct cancer. | ||||||||||
| Author: | Takasawa, Kumi|Takasawa, Akira|Osanai, Makoto|Aoyama, Tomoyuki|Ono, Yusuke|Kono, Tsuyoshi|Hirohashi, Yoshihiko|Murata, Masaki|Sawada, Norimasa | ||||||||||
| PMID: | 28624624 | ||||||||||
| 50. | |||||||||||
| Journal: | J Transl Med. 2017 Nov 25;15(1):238. | ||||||||||
| Title: | Autocrine parathyroid hormone-like hormone promotes intrahepatic cholangiocarcinoma cell proliferation via increased ERK/JNK-ATF2-cyclinD1 signaling. | ||||||||||
| Author: | Tang, Jing|Liao, Yan|He, Shuying|Shi, Jie|Peng, Liang|Xu, Xiaoping|Xie, Fang|Diao, Na|Huang, Jinlan|Xie, Qian|Lin, Chuang|Luo, Xiaoying|Liao, Kaili|Ma, Juanjuan|Li, Jingyi|Zhou, Daichao|Li, Zhijun|Xu, Jun|Zhong, Chao|Wang, Guozhen|Bai, Lan | ||||||||||
| PMID: | 29178939 | ||||||||||
| 51. | |||||||||||
| Journal: | Cytotechnology. 2018 Feb;70(1):439-448. | ||||||||||
| Title: | Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway. | ||||||||||
| Author: | Bi, Tingting|Zhu, Ao|Yang, Xufeng|Qiao, Huiying|Tang, Jinmei|Liu, Yan|Lv, Rong | ||||||||||
| PMID: | 29110119 | ||||||||||
| 52. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jan 18;9(2):31. | ||||||||||
| Title: | Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. | ||||||||||
| Author: | Dong, Mingjie|Liu, Xianqiong|Evert, Katja|Utpatel, Kirsten|Peters, Michele|Zhang, Shanshan|Xu, Zhong|Che, Li|Cigliano, Antonio|Ribback, Silvia|Dombrowski, Frank|Cossu, Antonio|Gordan, John|Calvisi, Diego F|Evert, Matthias|Liu, Yan|Chen, Xin | ||||||||||
| PMID: | 29348467 | ||||||||||
| 53. | |||||||||||
| Journal: | Cell Death Dis. 2018 Feb 7;9(2):179. | ||||||||||
| Title: | Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of beta-Catenin. | ||||||||||
| Author: | Zheng, Yan|Zhou, Chuang|Yu, Xin-Xin|Wu, Chao|Jia, Hu-Liang|Gao, Xiao-Mei|Yang, Ji-Meng|Wang, Chao-Qun|Luo, Qin|Zhu, Ying|Zhang, Yu|Wei, Jin-Wang|Sheng, Yuan-Yuan|Dong, Qiong-Zhu|Qin, Lun-Xiu | ||||||||||
| PMID: | 29415992 | ||||||||||
| 54. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2018 May 15;499(3):433-440. | ||||||||||
| Title: | Inhibition of KLHL21 prevents cholangiocarcinoma progression through regulating cell proliferation and motility, arresting cell cycle and reducing Erk activation. | ||||||||||
| Author: | Chen, Jian|Song, Wenfeng|Du, Yehui|Li, Zequn|Xuan, Zefeng|Zhao, Long|Chen, Jun|Zhao, Yongchao|Tuo, Biguang|Zheng, Shusen|Song, Penghong | ||||||||||
| PMID: | 29574153 | ||||||||||
| 55. | |||||||||||
| Journal: | Int J Mol Sci. 2018 Oct 12;19(10). pii: ijms19103141. | ||||||||||
| Title: | MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner. | ||||||||||
| Author: | Miao, Wenyu|Sakai, Katsuya|Imamura, Ryu|Ito, Kenichiro|Suga, Hiroaki|Sakuma, Tetsushi|Yamamoto, Takashi|Matsumoto, Kunio | ||||||||||
| PMID: | 30322054 | ||||||||||