Primary Site >> Liver Cancer

Gene >> MAP3K5

Journal: J Biol Chem. 2003 Oct 10;278(41):39615-24.
Title: Selenite-induced survival of HuH7 hepatoma cells involves activation of focal adhesion kinase-phosphatidylinositol 3-kinase-Akt pathway and Rac1.
Author: Lee, Yu-Chi|Tang, Yun-Chi|Chen, Yi-Hsien|Wong, Chiuan-Mei|Tsou, Ann-Ping
PMID: 12896980
Journal: Diabetes. 2006 May;55(5):1197-204.
Title: Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling.
Author: Imoto, Koujiro|Kukidome, Daisuke|Nishikawa, Takeshi|Matsuhisa, Takako|Sonoda, Kazuhiro|Fujisawa, Kazuo|Yano, Miyuki|Motoshima, Hiroyuki|Taguchi, Tetsuya|Tsuruzoe, Kaku|Matsumura, Takeshi|Ichijo, Hidenori|Araki, Eiichi
PMID: 16644673
Journal: Int J Cancer. 2008 Nov 1;123(9):2057-64.
Title: Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.
Author: Calvisi, Diego F|Pinna, Federico|Pellegrino, Rossella|Sanna, Valeria|Sini, Marcella|Daino, Lucia|Simile, Maria M|De Miglio, Maria R|Frau, Maddalena|Tomasi, Maria L|Seddaiu, Maria A|Muroni, Maria R|Feo, Francesco|Pascale, Rosa M
PMID: 18697198
Journal: World J Gastroenterol. 2008 Oct 21;14(39):6072-7.
Title: Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma.
Author: Lee, Chun-Feng|Ling, Zhi-Qiang|Zhao, Ting|Lee, Kuan-Rong
PMID: 18932288
Journal: Mol Carcinog. 2011 Aug;50(8):580-91.
Title: Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells.
Author: Ji, Lili|Shen, Kaikai|Jiang, Ping|Morahan, Grant|Wang, Zhengtao
PMID: 21319226
Journal: Hepatology. 2011 Jul;54(1):185-95.
Title: Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.
Author: Nakagawa, Hayato|Hirata, Yoshihiro|Takeda, Kohsuke|Hayakawa, Yoku|Sato, Takehiro|Kinoshita, Hiroto|Sakamoto, Kei|Nakata, Wachiko|Hikiba, Yohko|Omata, Masao|Yoshida, Haruhiko|Koike, Kazuhiko|Ichijo, Hidenori|Maeda, Shin
PMID: 21488081
Journal: Curr Cancer Drug Targets. 2011 Oct;11(8):944-53.
Title: Comparing the efficacy of sunitinib with sorafenib in xenograft models of human hepatocellular carcinoma: mechanistic explanation.
Author: Huynh, H|Choo, S P|Toh, H C|Tai, W M|Chung, A Y F|Chow, P K H|Ong, R|Soo, K C
PMID: 21834756
Journal: Hepatology. 2013 Jan;57(1):171-82.
Title: Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice.
Author: Lin, Heng|Yan, Jun|Wang, Ziyan|Hua, Fang|Yu, Jiaojiao|Sun, Wei|Li, Ke|Liu, Hong|Yang, Hongzhen|Lv, Qi|Xue, Jianfei|Hu, Zhuo-Wei
PMID: 22859216
Journal: Biochem Pharmacol. 2015 Jan 15;93(2):221-31.
Title: Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins.
Author: Xing, Su-Qian|Zhang, Chen-Guang|Yuan, Ji-Fang|Yang, Hui-Min|Zhao, Shu-Dong|Zhang, Hong
PMID: 25514170
Journal: Mol Med Rep. 2016 Feb;13(2):1570-6.
Title: Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells.
Author: Zheng, Ruinian|You, Zhijian|Jia, Jun|Lin, Shunhuan|Han, Shuai|Liu, Aixue|Long, Huidong|Wang, Senming
PMID: 26707143
Journal: Tohoku J Exp Med. 2016 Sep;240(1):67-78.
Title: Oxidative Stress Impairs the Stimulatory Effect of S100 Proteins on Protein Phosphatase 5 Activity.
Author: Yamaguchi, Fuminori|Tsuchiya, Mitsumasa|Shimamoto, Seiko|Fujimoto, Tomohito|Tokumitsu, Hiroshi|Tokuda, Masaaki|Kobayashi, Ryoji
PMID: 27600583
Journal: Oncol Lett. 2016 Aug;12(2):1034-1040.
Title: Hypoxia-inducible factor-1alpha mediates the toll-like receptor 4 signaling pathway leading to anti-tumor effects in human hepatocellular carcinoma cells under hypoxic conditions.
Author: Zhang, Xiaoyu|Li, Shuchen|Li, Mingrong|Huang, Haiying|Li, Jingyuan|Zhou, Changwei
PMID: 27446390
Journal: Oncotarget. 2016 May 10;7(19):27408-21.
Title: Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4alpha on hepatocellular carcinoma.
Author: Jiang, Cai-Feng|Wen, Liang-Zhi|Yin, Chuan|Xu, Wen-Ping|Shi, Bin|Zhang, Xin|Xie, Wei-Fen
PMID: 27050273
Journal: J Hepatol. 2016 Jul;65(1):113-124.
Title: DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity.
Author: Xie, Lanfeng|Wang, Pi-Xiao|Zhang, Peng|Zhang, Xiao-Jing|Zhao, Guang-Nian|Wang, Aibing|Guo, Junhong|Zhu, Xueyong|Zhang, Qin|Li, Hongliang
PMID: 27016281
Journal: Oncotarget. 2016 Apr 26;7(17):23860-73.
Title: IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1alpha and PERK signaling.
Author: Zhang, Na|Bi, Chongwen|Liu, Lu|Dou, Yueying|Tang, Sheng|Pang, Weiqiang|Deng, Hongbin|Song, Danqing
PMID: 27009865
Journal: Oncol Lett. 2016 Mar;11(3):2145-2151.
Title: Solanine-induced reactive oxygen species inhibit the growth of human hepatocellular carcinoma HepG2 cells.
Author: Meng, Xue-Qin|Zhang, Wei|Zhang, Feng|Yin, Sheng-Yong|Xie, Hai-Yang|Zhou, Lin|Zheng, Shu-Sen
PMID: 26998139
Journal: Biochem Biophys Res Commun. 2016 Mar 4;471(2):267-73.
Title: 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to inhibit hepatocellular carcinoma cells.
Author: Fu, Meili|Wan, Fuqiang|Li, Zhengling|Zhang, Fenghua
PMID: 26773495
Journal: PLoS One. 2016 Jan 4;11(1):e0145195.
Title: Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent.
Author: Lv, Huiqing|Zhang, Zhongmin|Wu, Xiaoyu|Wang, Yaoxia|Li, Chenglin|Gong, Weihong|Gui, Liang|Wang, Xin
PMID: 26727592
Journal: J Cell Biochem. 2016 Jun;117(6):1308-18.
Title: Elevated Expression of Hepatoma Up-Regulated Protein Inhibits gamma-Irradiation-Induced Apoptosis of Prostate Cancer Cells.
Author: Hassan, Mohamed|El Khattouti, Abdelouahid|Ejaeidi, Ahmed|Ma, Tangeng|Day, William A|Espinoza, Ingrid|Vijayakumar, Srinivasan|Gomez, Christian R
PMID: 26505164
Journal: Cell Death Dis. 2018 Feb 14;9(2):230.
Title: Glycogen synthase kinase-3beta inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma.
Author: Zhang, Na|Liu, Xiaojia|Liu, Lu|Deng, Zhesong|Zeng, Qingxuan|Pang, Weiqiang|Liu, Yang|Song, Danqing|Deng, Hongbin
PMID: 29445085
Journal: Expert Rev Gastroenterol Hepatol. 2018 Sep 27:1-10.
Title: An update on the recent advances in antifibrotic therapy.
Author: Tacke, Frank|Weiskirchen, Ralf
PMID: 30261763