Primary Site >> Liver Cancer

Gene >> MAP3K5

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Ref: Selenite-induced survival of HuH7 hepatoma cells involves activation of focal adhesion kinase-phosphatidylinositol 3-kinase-Akt pathway and Rac1.
PMID: 12896980
Ref: Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling.
PMID: 16644673
Ref: Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.
PMID: 18697198
Ref: Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma.
PMID: 18932288
Ref: Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells.
PMID: 21319226
Ref: Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.
PMID: 21488081
Ref: Comparing the efficacy of sunitinib with sorafenib in xenograft models of human hepatocellular carcinoma: mechanistic explanation.
PMID: 21834756
Ref: Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice.
PMID: 22859216
Ref: Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins.
PMID: 25514170
Ref: Elevated Expression of Hepatoma Up-Regulated Protein Inhibits gamma-Irradiation-Induced Apoptosis of Prostate Cancer Cells.
PMID: 26505164
Ref: Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells.
PMID: 26707143
Ref: Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent.
PMID: 26727592
Ref: 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to inhibit hepatocellular carcinoma cells.
PMID: 26773495
Ref: Solanine-induced reactive oxygen species inhibit the growth of human hepatocellular carcinoma HepG2 cells.
PMID: 26998139
Ref: IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1alpha and PERK signaling.
PMID: 27009865
Ref: DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity.
PMID: 27016281
Ref: Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4alpha on hepatocellular carcinoma.
PMID: 27050273
Ref: Hypoxia-inducible factor-1alpha mediates the toll-like receptor 4 signaling pathway leading to anti-tumor effects in human hepatocellular carcinoma cells under hypoxic conditions.
PMID: 27446390
Ref: Oxidative Stress Impairs the Stimulatory Effect of S100 Proteins on Protein Phosphatase 5 Activity.
PMID: 27600583
Ref: Glycogen synthase kinase-3beta inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma.
PMID: 29445085
Ref: An update on the recent advances in antifibrotic therapy.
PMID: 30261763