Primary Site >> Colorectal Cancer

Gene >> MAP3K14

Journal: Oncogene. 1999 Oct 28;18(44):6013-20.
Title: Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex.
Author: Plummer, S M|Holloway, K A|Manson, M M|Munks, R J|Kaptein, A|Farrow, S|Howells, L
PMID: 10557090
Journal: Ann N Y Acad Sci. 2002 Nov;973:414-8.
Title: Thalidomide suppresses the interleukin 1beta-induced NFkappaB signaling pathway in colon cancer cells.
Author: Jin, Soo Hyun|Kim, Tae Il|Han, Dong Soo|Shin, Sung Kwan|Kim, Won Ho
PMID: 12485902
Journal: J Biol Chem. 2004 Jun 18;279(25):26019-27. Epub 2004 Mar 26.
Title: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling.
Author: Nho, Chu Won|O'Dwyer, Peter J
PMID: 15047705
Journal: Cell Physiol Biochem. 2005;15(1-4):29-40.
Title: TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
Author: Ahn, Dae-ho|Crawley, Suzanne C|Hokari, Ryota|Kato, Shingo|Yang, Stacey C|Li, Jian-Dong|Kim, Young S
PMID: 15665513
Journal: J Pharmacol Exp Ther. 2006 Sep;318(3):939-46.
Title: Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.
Author: Petrangolini, Giovanna|Supino, Rosanna|Pratesi, Graziella|Dal Bo, Laura|Tortoreto, Monica|Croce, Anna Cleta|Misiano, Paola|Belfiore, Pietro|Farina, Carlo|Zunino, Franco
PMID: 16714402
Journal: Immunity. 2012 May 25;36(5):742-54.
Title: NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling.
Author: Allen, Irving C|Wilson, Justin E|Schneider, Monika|Lich, John D|Roberts, Reid A|Arthur, Janelle C|Woodford, Rita-Marie T|Davis, Beckley K|Uronis, Joshua M|Herfarth, Hans H|Jobin, Christian|Rogers, Arlin B|Ting, Jenny P-Y
PMID: 22503542
Journal: PLoS One. 2015 Mar 16;10(3):e0120361.
Title: The identification of specific methylation patterns across different cancers.
Author: Zhang, Chunlong|Zhao, Hongyan|Li, Jie|Liu, Hongbo|Wang, Fang|Wei, Yanjun|Su, Jianzhong|Zhang, Dongwei|Liu, Tiefu|Zhang, Yan
PMID: 25774687
Journal: Int J Mol Med. 2015 May;35(5):1266-72.
Title: Downregulation of miR-518a-3p activates the NIK-dependent NF-kappaB pathway in colorectal cancer.
Author: Qu, L L|He, L|Zhao, X|Xu, W
PMID: 25812680
Journal: Mol Med Rep. 2016 Jun;13(6):5379-85.
Title: NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-kappaB pathway.
Author: Xu, Chun-Yan|Qin, Meng-Bin|Tan, Lin|Liu, Shi-Quan|Huang, Jie-An
PMID: 27109343
Journal: J Pathol. 2016 Nov;240(3):352-365.
Title: Olfactomedin 1 negatively regulates NF-kappaB signalling and suppresses the growth and metastasis of colorectal cancer cells.
Author: Shi, Wei|Ye, Zhihua|Zhuang, Li|Li, Yingchang|Shuai, Wendi|Zuo, Zhixiang|Mao, Xueli|Liu, Ranyi|Wu, Jiangxue|Chen, Shuai|Huang, Wenlin
PMID: 27555280
Journal: PLoS One. 2017 Jan 26;12(1):e0170595.
Title: Knockdown of NIK and IKKbeta-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-kappaBeta Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.
Author: Qin, Mengbin|Zhang, Jinxiu|Xu, Chunyan|Peng, Peng|Tan, Lin|Liu, Shiquan|Huang, Jiean
PMID: 28125661
Journal: Oncotarget. 2018 Jun 19;9(47):28445-28455.
Title: Silencing NIK potentiates anti-VEGF therapy in a novel 3D model of colorectal cancer angiogenesis.
Author: Maracle, Chrissta X|Jeucken, Kim C M|Helder, Boy|van Gulik, Thomas M|Steins, Anne|van Laarhoven, Hanneke W M|Tas, Sander W
PMID: 29983872