Primary Site >> Colorectal Cancer

Gene >> MAP3K14

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Ref: Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex.
PMID: 10557090
Ref: Thalidomide suppresses the interleukin 1beta-induced NFkappaB signaling pathway in colon cancer cells.
PMID: 12485902
Ref: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling.
PMID: 15047705
Ref: TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
PMID: 15665513
Ref: Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.
PMID: 16714402
Ref: NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling.
PMID: 22503542
Ref: The identification of specific methylation patterns across different cancers.
PMID: 25774687
Ref: Downregulation of miR-518a-3p activates the NIK-dependent NF-kappaB pathway in colorectal cancer.
PMID: 25812680
Ref: NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-kappaB pathway.
PMID: 27109343
Ref: Olfactomedin 1 negatively regulates NF-kappaB signalling and suppresses the growth and metastasis of colorectal cancer cells.
PMID: 27555280
Ref: Knockdown of NIK and IKKbeta-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-kappaBeta Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.
PMID: 28125661
Ref: Silencing NIK potentiates anti-VEGF therapy in a novel 3D model of colorectal cancer angiogenesis.
PMID: 29983872