Primary Site >> Stomach Cancer
Gene >> MAP2K7
| 1. | |||||||||||
| Journal: | J Biol Chem. 1999 Jul 23;274(30):20961-9. | ||||||||||
| Title: | Activation of human histidine decarboxylase gene promoter activity by gastrin is mediated by two distinct nuclear factors. | ||||||||||
| Author: | Raychowdhury, R|Zhang, Z|Hocker, M|Wang, T C | ||||||||||
| PMID: | 10409643 | ||||||||||
| 2. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2001 Oct;16(10):1098-104. | ||||||||||
| Title: | Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. | ||||||||||
| Author: | Fan, X M|Wong, B C|Lin, M C|Cho, C H|Wang, W P|Kung, H F|Lam, S K | ||||||||||
| PMID: | 11686835 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2003 Aug;125(2):510-21. | ||||||||||
| Title: | Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. | ||||||||||
| Author: | Khan, Zara E|Wang, Timothy C|Cui, Guanglin|Chi, Alfred L|Dimaline, Rod | ||||||||||
| PMID: | 12891554 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2003 Jan 30;22(4):548-54. | ||||||||||
| Title: | Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway. | ||||||||||
| Author: | Kanai, Masashi|Konda, Yoshitaka|Nakajima, Toshio|Izumi, Yoshio|Kanda, Naoki|Nanakin, Apichart|Kubohara, Yuzuru|Chiba, Tsutomu | ||||||||||
| PMID: | 12555068 | ||||||||||
| 5. | |||||||||||
| Journal: | J Natl Cancer Inst. 2004 Nov 17;96(22):1691-702. | ||||||||||
| Title: | Reactivation of latent Epstein-Barr virus by methotrexate: a potential contributor to methotrexate-associated lymphomas. | ||||||||||
| Author: | Feng, Wen-hai|Cohen, Jeffrey I|Fischer, Steven|Li, Li|Sneller, Michael|Goldbach-Mansky, Raphael|Raab-Traub, Nancy|Delecluse, Henri-Jacques|Kenney, Shannon C | ||||||||||
| PMID: | 15547182 | ||||||||||
| 6. | |||||||||||
| Journal: | Biochemistry. 2005 Mar 15;44(10):4074-82. | ||||||||||
| Title: | A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. | ||||||||||
| Author: | Antignani, Antonella|Youle, Richard J | ||||||||||
| PMID: | 15751984 | ||||||||||
| 7. | |||||||||||
| Journal: | Exp Mol Med. 2006 Feb 28;38(1):27-35. | ||||||||||
| Title: | Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines. | ||||||||||
| Author: | Lee, Kyung Hee|Choi, Eun Young|Kim, Min Kyoung|Hyun, Myung Soo|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong | ||||||||||
| PMID: | 16520550 | ||||||||||
| 8. | |||||||||||
| Journal: | FASEB J. 2006 Sep;20(11):1886-8. Epub 2006 Jul 28. | ||||||||||
| Title: | Cellular prion protein promotes invasion and metastasis of gastric cancer. | ||||||||||
| Author: | Pan, Yanglin|Zhao, Lina|Liang, Jie|Liu, Jie|Shi, Yongquan|Liu, Na|Zhang, Guoyun|Jin, Haifeng|Gao, Juan|Xie, Huahong|Wang, Jun|Liu, Zhiguo|Fan, Daiming | ||||||||||
| PMID: | 16877520 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncol Res. 2008;17(1):23-32. | ||||||||||
| Title: | Hepatocyte growth factor promotes cell survival by phosphorylation of BAD in gastric cancer cells. | ||||||||||
| Author: | Lee, Kyung Hee|Choi, Eun Young|Kim, Min Kyoung|Hyun, Myung Soo|Eun, Jong Ryul|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong | ||||||||||
| PMID: | 18488712 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Ther. 2008 Nov;7(11):3499-508. | ||||||||||
| Title: | HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells. | ||||||||||
| Author: | Bachleitner-Hofmann, Thomas|Sun, Mark Y|Chen, Chin-Tung|Tang, Laura|Song, Lin|Zeng, Zhaoshi|Shah, Manish|Christensen, James G|Rosen, Neal|Solit, David B|Weiser, Martin R | ||||||||||
| PMID: | 18974395 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Sep;8(9):2526-36. | ||||||||||
| Title: | Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells. | ||||||||||
| Author: | Yoon, Young-Kwang|Kim, Hwang-Phill|Han, Sae-Won|Hur, Hyung-Seok|Oh, Do Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You | ||||||||||
| PMID: | 19755509 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Sci. 2009 Jun;100(6):1118-27. | ||||||||||
| Title: | Breast cancer resistance protein/ABCG2 is differentially regulated downstream of extracellular signal-regulated kinase. | ||||||||||
| Author: | Imai, Yasuo|Ohmori, Kyoko|Yasuda, Shin'ichi|Wada, Mariko|Suzuki, Tsukasa|Fukuda, Kazunori|Ueda, Yoshihiko | ||||||||||
| PMID: | 19514121 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Lett. 2009 Feb 8;274(1):40-6. | ||||||||||
| Title: | Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells. | ||||||||||
| Author: | Zhang, Lin Jie|Chen, Si|Wu, Pin|Hu, Chun Song|Thorne, Rick F|Luo, Chang Ming|Hersey, Peter|Zhang, Xu Dong | ||||||||||
| PMID: | 18829155 | ||||||||||
| 14. | |||||||||||
| Journal: | Int J Cancer. 2010 Aug 15;127(4):820-9. | ||||||||||
| Title: | ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer. | ||||||||||
| Author: | Liu, Lili|Zhang, Hongbo|Sun, Li|Gao, Yuqi|Jin, Haifeng|Liang, Shuhui|Wang, Yanxia|Dong, Mingqing|Shi, Yongquan|Li, Zhichao|Fan, Daiming | ||||||||||
| PMID: | 19998339 | ||||||||||
| 15. | |||||||||||
| Journal: | Autophagy. 2010 Feb;6(2):228-38. Epub 2010 Feb 24. | ||||||||||
| Title: | Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells. | ||||||||||
| Author: | Wu, William Ka Kei|Cho, Chi Hin|Lee, Chung Wa|Wu, Ya Chun|Yu, Le|Li, Zhi Jie|Wong, Clover Ching Man|Li, Hai Tao|Zhang, Lin|Ren, Shun Xiang|Che, Chun Tao|Wu, Kaichun|Fan, Daiming|Yu, Jun|Sung, Joseph Jao Yiu | ||||||||||
| PMID: | 20087064 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Biol Ther. 2010 Jun 15;9(12):1000-7. Epub 2010 Jun 7. | ||||||||||
| Title: | Critical role of aquaporin-3 in the human epidermal growth factor-induced migration and proliferation in the human gastric adenocarcinoma cells. | ||||||||||
| Author: | Huang, Yiming|Zhu, Zhengcai|Sun, Maocai|Wang, Jianping|Guo, Renhua|Shen, Lizong|Wu, Wenxi | ||||||||||
| PMID: | 20364107 | ||||||||||
| 17. | |||||||||||
| Journal: | Anticancer Res. 2010 Jun;30(6):2135-43. | ||||||||||
| Title: | Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. | ||||||||||
| Author: | Yang, Mei-Due|Lai, Kuang-Chi|Lai, Tung-Yuan|Hsu, Shu-Chun|Kuo, Chao-Lin|Yu, Chun-Shu|Lin, Meng-Liang|Yang, Jai-Sing|Kuo, Hsiu-Maan|Wu, Shin-Hwar|Chung, Jing-Gung | ||||||||||
| PMID: | 20651362 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Res. 2010 Nov;8(11):1477-88. | ||||||||||
| Title: | CADPE inhibits PMA-stimulated gastric carcinoma cell invasion and matrix metalloproteinase-9 expression by FAK/MEK/ERK-mediated AP-1 activation. | ||||||||||
| Author: | Han, Honghui|Du, Bing|Pan, Xinhua|Liu, Junchen|Zhao, Qufei|Lian, Xiaoyuan|Qian, Min|Liu, Mingyao | ||||||||||
| PMID: | 21047770 | ||||||||||
| 19. | |||||||||||
| Journal: | Exp Mol Med. 2011 Sep 30;43(9):501-9. | ||||||||||
| Title: | Down-regulation of survivin suppresses uro-plasminogen activator through transcription factor JunB. | ||||||||||
| Author: | Lee, Kyung Hee|Choi, Eun Young|Koh, Sung Ae|Kim, Min Kyoung|Kim, Kyeong Ok|Lee, Si Hyung|Jang, Byung Ik|Kim, Se Won|Kim, Sang Woon|Song, Sun Kyo|Choi, Joon Hyuk|Kim, Jae-Ryong | ||||||||||
| PMID: | 21734448 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2011;6(6):e21155. | ||||||||||
| Title: | Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study. | ||||||||||
| Author: | Yang, Jae Jeong|Cho, Lisa Y|Ma, Seung Hyun|Ko, Kwang-Pil|Shin, Aesun|Choi, Bo Youl|Han, Dong Soo|Song, Kyu Sang|Kim, Yong Sung|Chang, Soung-Hoon|Shin, Hai-Rim|Kang, Daehee|Yoo, Keun-Young|Park, Sue K | ||||||||||
| PMID: | 21698158 | ||||||||||
| 21. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Apr 15;17(8):2130-9. | ||||||||||
| Title: | Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. | ||||||||||
| Author: | Kang, Wei|Tong, Joanna H M|Chan, Anthony W H|Lee, Tin-Lap|Lung, Raymond W M|Leung, Patrick P S|So, Ken K Y|Wu, Kaichun|Fan, Daiming|Yu, Jun|Sung, Joseph J Y|To, Ka-Fai | ||||||||||
| PMID: | 21346147 | ||||||||||
| 22. | |||||||||||
| Journal: | Hum Exp Toxicol. 2011 Apr;30(4):296-306. | ||||||||||
| Title: | Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways. | ||||||||||
| Author: | Ho, Chin-Chin|Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Ma, Chia-Yu|Lin, Meng-Liang|Yang, Jai-Sing|Chung, Jing-Gung | ||||||||||
| PMID: | 20498032 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Res. 2011 Feb 1;71(3):1081-91. | ||||||||||
| Title: | Multiple mutations and bypass mechanisms can contribute to development of acquired resistance to MET inhibitors. | ||||||||||
| Author: | Qi, Jie|McTigue, Michele A|Rogers, Andrew|Lifshits, Eugene|Christensen, James G|Janne, Pasi A|Engelman, Jeffrey A | ||||||||||
| PMID: | 21266357 | ||||||||||
| 24. | |||||||||||
| Journal: | Theor Biol Med Model. 2012 Dec 11;9(1):53. | ||||||||||
| Title: | p42.3 gene expression in gastric cancer cell and its protein regulatory network analysis. | ||||||||||
| Author: | Zhang, Jianhua|Lu, Chunlei|Shang, Zhigang|Xing, Rui|Shi, Li|Lv, Youyong | ||||||||||
| PMID: | 23228105 | ||||||||||
| 25. | |||||||||||
| Journal: | PLoS One. 2012;7(7):e41773. | ||||||||||
| Title: | beta,beta-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells. | ||||||||||
| Author: | Shen, Xiu-Jin|Wang, Hai-Bing|Ma, Xiao-Qiong|Chen, Jiang-Hua | ||||||||||
| PMID: | 22848597 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncol Rep. 2012 Oct;28(4):1429-34. | ||||||||||
| Title: | Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells. | ||||||||||
| Author: | Lim, Sung-Chul|Duong, Hong-Quan|Parajuli, Keshab Raj|Han, Song Iy | ||||||||||
| PMID: | 22824956 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2012;7(6):e39653. | ||||||||||
| Title: | A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation. | ||||||||||
| Author: | Lee, Nathan V|Lira, Maruja E|Pavlicek, Adam|Ye, Jingjing|Buckman, Dana|Bagrodia, Shubha|Srinivasa, Sreesha P|Zhao, Yongjun|Aparicio, Samuel|Rejto, Paul A|Christensen, James G|Ching, Keith A | ||||||||||
| PMID: | 22745804 | ||||||||||
| 28. | |||||||||||
| Journal: | BMC Immunol. 2012 Jun 6;13:28. | ||||||||||
| Title: | Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer. | ||||||||||
| Author: | Yang, Donghai|Fan, Xin|Yin, Ping|Wen, Qiang|Yan, Feng|Yuan, Sibo|Liu, Bin|Zhuang, Guohong|Liu, Zhongchen | ||||||||||
| PMID: | 22672288 | ||||||||||
| 29. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2012 Mar 31;31:30. | ||||||||||
| Title: | Prognostic value of RKIP and p-ERK in gastric cancer. | ||||||||||
| Author: | Fujimori, Yoshitaka|Inokuchi, Mikito|Takagi, Yoko|Kato, Keiji|Kojima, Kazuyuki|Sugihara, Kenichi | ||||||||||
| PMID: | 22463874 | ||||||||||
| 30. | |||||||||||
| Journal: | PLoS One. 2012;7(2):e31729. | ||||||||||
| Title: | Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells. | ||||||||||
| Author: | Liu, Zhi|Xing, Mingzhao | ||||||||||
| PMID: | 22359623 | ||||||||||
| 31. | |||||||||||
| Journal: | Immunobiology. 2012 Sep;217(9):926-34. | ||||||||||
| Title: | Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer. | ||||||||||
| Author: | Tseng, Po-Chun|Huang, Wei-Ching|Chen, Chia-Ling|Sheu, Bor-Shyang|Shan, Yan-Shen|Tsai, Cheng-Chieh|Wang, Chi-Yun|Chen, Su-O|Hsieh, Chia-Yuan|Lin, Chiou-Feng | ||||||||||
| PMID: | 22325465 | ||||||||||
| 32. | |||||||||||
| Journal: | Gut. 2013 Oct;62(10):1415-24. | ||||||||||
| Title: | A systematic approach to therapeutic target selection in oesophago-gastric cancer. | ||||||||||
| Author: | Paterson, Anna L|Shannon, Nicholas B|Lao-Sirieix, Pierre|Ong, Chin-Ann J|Peters, Christopher J|O'Donovan, Maria|Fitzgerald, Rebecca C | ||||||||||
| PMID: | 22773546 | ||||||||||
| 33. | |||||||||||
| Journal: | Pathol Oncol Res. 2013 Jan;19(1):11-8. | ||||||||||
| Title: | Semaphorin 5A, an axon guidance molecule, enhances the invasion and metastasis of human gastric cancer through activation of MMP9. | ||||||||||
| Author: | Pan, Guoqing|Zhang, Xiangling|Ren, Junyu|Lu, Jianbo|Li, Wenliang|Fu, Hongmei|Zhang, Shufang|Li, Jun | ||||||||||
| PMID: | 22821546 | ||||||||||
| 34. | |||||||||||
| Journal: | Cancer Lett. 2013 May 10;332(1):74-82. | ||||||||||
| Title: | KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer. | ||||||||||
| Author: | Hong, Sang-Won|Jung, Kyung-Hee|Park, Byung Hee|Zheng, Hong-Mei|Lee, Hee-Seung|Choi, Myung-Joo|Yun, Jeong In|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun | ||||||||||
| PMID: | 23348694 | ||||||||||
| 35. | |||||||||||
| Journal: | Biochem Pharmacol. 2013 May 1;85(9):1246-56. | ||||||||||
| Title: | Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. | ||||||||||
| Author: | Lu, Chunwan|Liu, Di|Jin, Jing|Deokar, Hemantkumar|Zhang, Yi|Buolamwini, John K|Yu, Xiaoming|Yan, Chunhong|Chen, Xiaoguang | ||||||||||
| PMID: | 23415900 | ||||||||||
| 36. | |||||||||||
| Journal: | Biosci Rep. 2014 Apr 1;34(2). pii: BSR20130102. | ||||||||||
| Title: | PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways. | ||||||||||
| Author: | Fu, Xueqiong|Feng, Jiarui|Zeng, Duan|Ding, Yu|Yu, Changshou|Yang, Bing | ||||||||||
| PMID: | 27919028 | ||||||||||
| 37. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 Dec;13(12):3098-106. | ||||||||||
| Title: | MEK inhibitor for gastric cancer with MEK1 gene mutations. | ||||||||||
| Author: | Sogabe, Shunsuke|Togashi, Yosuke|Kato, Hiroaki|Kogita, Akihiro|Mizukami, Takuro|Sakamoto, Yoichi|Banno, Eri|Terashima, Masato|Hayashi, Hidetoshi|de Velasco, Marco A|Sakai, Kazuko|Fujita, Yoshihiko|Tomida, Shuta|Yasuda, Takushi|Takeyama, Yoshifumi|Okuno, K | ||||||||||
| PMID: | 25253779 | ||||||||||
| 38. | |||||||||||
| Journal: | FASEB J. 2014 Sep;28(9):4055-67. | ||||||||||
| Title: | Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy. | ||||||||||
| Author: | Musiani, Daniele|Konda, John David|Pavan, Simona|Torchiaro, Erica|Sassi, Francesco|Noghero, Alessio|Erriquez, Jessica|Perera, Timothy|Olivero, Martina|Di Renzo, Maria Flavia | ||||||||||
| PMID: | 24903273 | ||||||||||
| 39. | |||||||||||
| Journal: | Sci Signal. 2014 Apr 22;7(322):ra38. | ||||||||||
| Title: | Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer. | ||||||||||
| Author: | Lai, Andrea Z|Cory, Sean|Zhao, Hong|Gigoux, Mathieu|Monast, Anie|Guiot, Marie-Christine|Huang, Sidong|Tofigh, Ali|Thompson, Crista|Naujokas, Monica|Marcus, Victoria A|Bertos, Nicholas|Sehat, Bita|Perera, Rushika M|Bell, Emily S|Page, Brent D G|Gunning, Pa | ||||||||||
| PMID: | 24757178 | ||||||||||
| 40. | |||||||||||
| Journal: | PLoS One. 2014 Jan 20;9(1):e85296. | ||||||||||
| Title: | Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer. | ||||||||||
| Author: | Lin, Zhaohu|Zhang, Chao|Zhang, Meifang|Xu, Danqing|Fang, Yanfen|Zhou, Zheng|Chen, Xiaolong|Qin, Ning|Zhang, Xiongwen | ||||||||||
| PMID: | 24465527 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Lett. 2014 May 28;347(1):123-8. | ||||||||||
| Title: | A novel PP2A enhancer induces caspase-independent apoptosis of MKN28 gastric cancer cells with high MEK activity. | ||||||||||
| Author: | Tsuchiya, Ayako|Kanno, Takeshi|Shimizu, Tadashi|Nakao, Syuhei|Tanaka, Akito|Tabata, Chiharu|Nakano, Takashi|Nishizaki, Tomoyuki | ||||||||||
| PMID: | 24508028 | ||||||||||
| 42. | |||||||||||
| Journal: | Neoplasma. 2014;61(2):136-43. | ||||||||||
| Title: | Inhibition of MEK sensitizes gastric cancer cells to TRAIL-induced apoptosis. | ||||||||||
| Author: | Wu, P|Cheng, Y W|Wang, J Y|Zhang, X D|Zhang, L J | ||||||||||
| PMID: | 24299309 | ||||||||||
| 43. | |||||||||||
| Journal: | PLoS One. 2014 Jan 9;9(1):e85116. | ||||||||||
| Title: | The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway. | ||||||||||
| Author: | Ji, Dongmei|Zhang, Zhe|Cheng, Lei|Chang, Jinjia|Wang, Shanshan|Zheng, Biqiang|Zheng, Rongliang|Sun, Zuojun|Wang, Chenchen|Zhang, Zhiqing|Liu, Rujiao|Zhang, Xiaowei|Liu, Xin|Wang, Xiaofeng|Li, Jin | ||||||||||
| PMID: | 24416349 | ||||||||||
| 44. | |||||||||||
| Journal: | Environ Toxicol. 2015 Mar;30(3):315-22. | ||||||||||
| Title: | Pb(2)(+) induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells. | ||||||||||
| Author: | Lin, Ying-Chi|Wei, Po-Li|Tsai, Yao-Ting|Wong, Jhen-Hong|Chang, Che-Mai|Wang, Jaw-Yuan|Hou, Ming-Feng|Lee, Yi-Chao|Chuang, Hung-Yi|Chang, Wei-Chiao | ||||||||||
| PMID: | 24106166 | ||||||||||
| 45. | |||||||||||
| Journal: | Gut. 2015 Jan;64(1):37-48. | ||||||||||
| Title: | OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer. | ||||||||||
| Author: | Qian, Jin|Kong, Xuan|Deng, Niantao|Tan, Patrick|Chen, Haoyan|Wang, Jilin|Li, Zhaoli|Hu, Ye|Zou, Weiping|Xu, Jie|Fang, Jing-Yuan | ||||||||||
| PMID: | 24717932 | ||||||||||
| 46. | |||||||||||
| Journal: | Tumour Biol. 2015 Apr;36(4):2773-8. | ||||||||||
| Title: | Bone morphogenetic protein 2 mediates epithelial-mesenchymal transition via AKT and ERK signaling pathways in gastric cancer. | ||||||||||
| Author: | Liao, Anyan|Wang, Weijie|Sun, Dawei|Jiang, Yuliang|Tian, Suqing|Li, Jinna|Yang, Xiangshan|Shi, Ranran | ||||||||||
| PMID: | 25448881 | ||||||||||
| 47. | |||||||||||
| Journal: | Oncotarget. 2015 Jan 1;6(1):221-33. | ||||||||||
| Title: | Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells. | ||||||||||
| Author: | Petti, Consalvo|Picco, Gabriele|Martelli, Maria Luisa|Trisolini, Elena|Bucci, Enrico|Perera, Timothy|Isella, Claudio|Medico, Enzo | ||||||||||
| PMID: | 25473895 | ||||||||||
| 48. | |||||||||||
| Journal: | Cancer Gene Ther. 2015 Feb 27. pii: cgt20156. | ||||||||||
| Title: | MALAT2-activated long noncoding RNA indicates a biomarker of poor prognosis in gastric cancer. | ||||||||||
| Author: | Chen, F|Tian, Y|Pang, E-J|Wang, Y|Li, L | ||||||||||
| PMID: | 25721209 | ||||||||||
| 49. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2015;16(3):1077-82. | ||||||||||
| Title: | RASAL1 attenuates gastric carcinogenesis in nude mice by blocking RAS/ERK signaling. | ||||||||||
| Author: | Chen, Hong|Zhao, Ji-Yi|Qian, Xu-Chen|Cheng, Zheng-Yuan|Liu, Yang|Wang, Zhi | ||||||||||
| PMID: | 25735335 | ||||||||||
| 50. | |||||||||||
| Journal: | Int J Oncol. 2015 Aug;47(2):499-505. | ||||||||||
| Title: | EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition. | ||||||||||
| Author: | Mizukami, Takuro|Togashi, Yosuke|Sogabe, Shunsuke|Banno, Eri|Terashima, Masato|De Velasco, Marco A|Sakai, Kazuko|Fujita, Yoshihiko|Tomida, Shuta|Nakajima, Takako Eguchi|Boku, Narikazu|Nishio, Kazuto | ||||||||||
| PMID: | 26081723 | ||||||||||
| 51. | |||||||||||
| Journal: | Cell Cycle. 2015 Aug 3;14(15):2473-83. | ||||||||||
| Title: | Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer. | ||||||||||
| Author: | Ji, Runbi|Zhang, Bin|Zhang, Xu|Xue, Jianguo|Yuan, Xiao|Yan, Yongmin|Wang, Mei|Zhu, Wei|Qian, Hui|Xu, Wenrong | ||||||||||
| PMID: | 26091251 | ||||||||||
| 52. | |||||||||||
| Journal: | Oncol Lett. 2015 Jul;10(1):502-508. | ||||||||||
| Title: | Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells. | ||||||||||
| Author: | Wang, Ying|Chen, Yongchang|Wu, Min|Lan, Ting|Wu, Yan|Li, Yueying|Qian, Hai | ||||||||||
| PMID: | 26171059 | ||||||||||
| 53. | |||||||||||
| Journal: | Oncol Rep. 2015 Oct;34(4):2179-87. | ||||||||||
| Title: | HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-kappaB activation. | ||||||||||
| Author: | Koh, Sung Ae|Lee, Kyung Hee | ||||||||||
| PMID: | 26259977 | ||||||||||
| 54. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2015 Dec;38(6):479-84. | ||||||||||
| Title: | DBD-F induces apoptosis in gastric cancer-derived cells through suppressing HIF2alpha expression. | ||||||||||
| Author: | Tong, Guang-Hui|Tong, Wei-Wei|Qin, Xiao-Song|Lu, Li-Ping|Liu, Yong | ||||||||||
| PMID: | 26526811 | ||||||||||
| 55. | |||||||||||
| Journal: | Exp Dermatol. 2016 Nov;25(11):831-838. | ||||||||||
| Title: | Inhibition of histone deacetylases in melanoma-a perspective from bench to bedside. | ||||||||||
| Author: | Hornig, Eva|Heppt, Markus V|Graf, Saskia A|Ruzicka, Thomas|Berking, Carola | ||||||||||
| PMID: | 27792246 | ||||||||||
| 56. | |||||||||||
| Journal: | Cancer Sci. 2016 Dec;107(12):1919-1928. | ||||||||||
| Title: | Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells. | ||||||||||
| Author: | Hirashita, Yuka|Tsukamoto, Yoshiyuki|Yanagihara, Kazuyoshi|Fumoto, Shoichi|Hijiya, Naoki|Nakada, Chisato|Uchida, Tomohisa|Matsuura, Keiko|Kodama, Masaaki|Okimoto, Tadayoshi|Daa, Tsutomu|Seike, Masataka|Iha, Hidekatsu|Shirao, Kuniaki|Murakami, Kazunari|Mor | ||||||||||
| PMID: | 27699948 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 9;7(32):51943-51954. | ||||||||||
| Title: | MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2. | ||||||||||
| Author: | Zhou, Lin|Liang, Xin|Zhang, Lingling|Yang, Liyan|Nagao, Norio|Wu, Hongkun|Liu, Chang|Lin, Shengchao|Cai, Guoxiang|Liu, Jianwen | ||||||||||
| PMID: | 27409164 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 14;7(24):36865-36884. | ||||||||||
| Title: | JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients. | ||||||||||
| Author: | Qian, Jing|Zhu, Weiyou|Wang, Keming|Ma, Lin|Xu, Jin|Xu, Tongpeng|Roe, Oluf Dimitri|Li, Aiping|Zhou, Jianwei|Shu, Yongqian | ||||||||||
| PMID: | 27167206 | ||||||||||
| 59. | |||||||||||
| Journal: | Tumour Biol. 2016 Sep;37(9):11799-11804. | ||||||||||
| Title: | The roles of serum PDCD5 in circulating CD133 positive cells of the patients with gastric cancer. | ||||||||||
| Author: | Wang, Dan|Wang, Wei|Song, Chang-Liang|Xia, Pu | ||||||||||
| PMID: | 27034262 | ||||||||||
| 60. | |||||||||||
| Journal: | Tumour Biol. 2016 Jul;37(7):9849-54. | ||||||||||
| Title: | The tumor promoting roles of HSP60 and HIF2alpha in gastric cancer cells. | ||||||||||
| Author: | Tong, Wei-Wei|Tong, Guang-Hui|Kong, Hong|Liu, Yong | ||||||||||
| PMID: | 26810190 | ||||||||||
| 61. | |||||||||||
| Journal: | Tumour Biol. 2016 Jul;37(7):9221-32. | ||||||||||
| Title: | DCT015, a new sorafenib derivate, inhibits tumor growth and angiogenesis in gastric cancer models. | ||||||||||
| Author: | Wang, Wenyan|Wang, Hui|Ni, Yingying|Yao, Zhenming|Ye, Liang|Tian, Jingwei | ||||||||||
| PMID: | 26768619 | ||||||||||
| 62. | |||||||||||
| Journal: | Int J Cancer. 2016 Jan 1;138(1):125-36. | ||||||||||
| Title: | Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. | ||||||||||
| Author: | Hui, Kwai Fung|Cheung, Arthur Kwok Leung|Choi, Chung King|Yeung, Po Ling|Middeldorp, Jaap M|Lung, Maria Li|Tsao, Sai Wah|Chiang, Alan Kwok Shing | ||||||||||
| PMID: | 26205347 | ||||||||||
| 63. | |||||||||||
| Journal: | Oncol Rep. 2016 Jun;35(6):3496-504. | ||||||||||
| Title: | Stromal interaction molecule 1 plays an important role in gastric cancer progression. | ||||||||||
| Author: | Xu, Jin-Mei|Zhou, Yan|Gao, Long|Zhou, Shu-Xian|Liu, Wei-Hua|Li, Xiao-An | ||||||||||
| PMID: | 27035326 | ||||||||||
| 64. | |||||||||||
| Journal: | Mol Cancer. 2017 Jan 23;16(1):18. | ||||||||||
| Title: | Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway. | ||||||||||
| Author: | Zhang, Jia-Xing|Xu, Yi|Gao, Ying|Chen, Cui|Zheng, Zhou-San|Yun, Miao|Weng, Hui-Wen|Xie, Dan|Ye, Sheng | ||||||||||
| PMID: | 28114937 | ||||||||||
| 65. | |||||||||||
| Journal: | J Transl Med. 2017 May 1;15(1):92. | ||||||||||
| Title: | Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer. | ||||||||||
| Author: | Chen, Ina|Mathews-Greiner, Lesley|Li, Dandan|Abisoye-Ogunniyan, Abisola|Ray, Satyajit|Bian, Yansong|Shukla, Vivek|Zhang, Xiaohu|Guha, Raj|Thomas, Craig|Gryder, Berkley|Zacharia, Athina|Beane, Joal D|Ravichandran, Sarangan|Ferrer, Marc|Rudloff, Udo | ||||||||||
| PMID: | 28460635 | ||||||||||
| 66. | |||||||||||
| Journal: | Sci Rep. 2017 Jun 9;7(1):3153. | ||||||||||
| Title: | FPR2 promotes invasion and metastasis of gastric cancer cells and predicts the prognosis of patients. | ||||||||||
| Author: | Hou, Xi-Lu|Ji, Cheng-Dong|Tang, Jun|Wang, Yan-Xia|Xiang, Dong-Fang|Li, Hai-Qing|Liu, Wei-Wei|Wang, Jiao-Xue|Yan, He-Zhong|Wang, Yan|Zhang, Peng|Cui, You-Hong|Wang, Ji-Ming|Bian, Xiu-Wu|Liu, Wei | ||||||||||
| PMID: | 28600569 | ||||||||||
| 67. | |||||||||||
| Journal: | Anticancer Drugs. 2017 Nov;28(10):1141-1149. | ||||||||||
| Title: | Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer. | ||||||||||
| Author: | Jin, Junfei|Xiong, Ying|Cen, Bo | ||||||||||
| PMID: | 28885267 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncotarget. 2017 May 23;8(64):107492-107499. | ||||||||||
| Title: | Correlation between MEK signature and Ras gene alteration in advanced gastric cancer. | ||||||||||
| Author: | Ahn, Soomin|Brant, Roz|Sharpe, Alan|Dry, Jonathan R|Hodgson, Darren R|Kilgour, Elaine|Kim, Kyung|Kim, Seung Tae|Park, Se Hoon|Kang, Won Ki|Kim, Kyoung-Mee|Lee, Jeeyun | ||||||||||
| PMID: | 29296181 | ||||||||||
| 69. | |||||||||||
| Journal: | Onco Targets Ther. 2018 Sep 25;11:6239-6247. | ||||||||||
| Title: | PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models. | ||||||||||
| Author: | Dang, Sheng-Chun|Fan, Yi-Yi|Cui, Lei|Chen, Ji-Xiang|Qu, Jian-Guo|Gu, Min | ||||||||||
| PMID: | 30288059 | ||||||||||
| 70. | |||||||||||
| Journal: | Int J Mol Sci. 2018 Aug 15;19(8). pii: ijms19082411. | ||||||||||
| Title: | Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers. | ||||||||||
| Author: | Cevenini, Armando|Orru, Stefania|Mancini, Annamaria|Alfieri, Andreina|Buono, Pasqualina|Imperlini, Esther | ||||||||||
| PMID: | 30111747 | ||||||||||
| 71. | |||||||||||
| Journal: | Mol Cancer Ther. 2018 Jul 25. pii: 1535-7163.MCT-17-1022. | ||||||||||
| Title: | Acquired JHDM1D-BRAF fusion confers resistance to FGFR inhibition in FGFR2- amplified gastric cancer. | ||||||||||
| Author: | Sase, Hitoshi|Nakanishi, Yoshito|Aida, Satoshi|Horiguchi-Takei, Kana|Akiyama, Nukinori|Fujii, Toshihiko|Sakata, Kiyoaki|Mio, Toshiyuki|Aoki, Masahiro|Ishii, Nobuya | ||||||||||
| PMID: | 30045926 | ||||||||||
| 72. | |||||||||||
| Journal: | Nat Med. 2018 Jul;24(7):968-977. | ||||||||||
| Title: | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. | ||||||||||
| Author: | Wong, Gabrielle S|Zhou, Jin|Liu, Jie Bin|Wu, Zhong|Xu, Xinsen|Li, Tianxia|Xu, David|Schumacher, Steven E|Puschhof, Jens|McFarland, James|Zou, Charles|Dulak, Austin|Henderson, Les|Xu, Peng|O'Day, Emily|Rendak, Rachel|Liao, Wei-Li|Cecchi, Fabiola|Hembrough, | ||||||||||
| PMID: | 29808010 | ||||||||||
| 73. | |||||||||||
| Journal: | Sci Signal. 2018 Apr 17;11(526). pii: 11/526/eaan6776. | ||||||||||
| Title: | Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases. | ||||||||||
| Author: | Hudson, Andrew M|Stephenson, Natalie L|Li, Cynthia|Trotter, Eleanor|Fletcher, Adam J|Katona, Gitta|Bieniasz-Krzywiec, Patrycja|Howell, Matthew|Wirth, Chris|Furney, Simon|Miller, Crispin J|Brognard, John | ||||||||||
| PMID: | 29666306 | ||||||||||
| 74. | |||||||||||
| Journal: | Clin Transl Med. 2018 Feb 22;7(1):7. | ||||||||||
| Title: | Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk. | ||||||||||
| Author: | Li, Dandan|Lo, Winifred|Rudloff, Udo | ||||||||||
| PMID: | 29468433 | ||||||||||
| 75. | |||||||||||
| Journal: | Int J Oncol. 2018 Mar;52(3):804-814. | ||||||||||
| Title: | BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells. | ||||||||||
| Author: | Lian, Guodong|Li, Leping|Shi, Yulong|Jing, Changqing|Liu, Jinglei|Guo, Xiaobo|Zhang, Qingqing|Dai, Tianyu|Ye, Fei|Wang, Yanyan|Chen, Man | ||||||||||
| PMID: | 29393385 | ||||||||||
| 76. | |||||||||||
| Journal: | Int J Mol Med. 2018 Apr;41(4):2389-2396. | ||||||||||
| Title: | Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway. | ||||||||||
| Author: | Su, Chin-Cheng | ||||||||||
| PMID: | 29393362 | ||||||||||
| 77. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jan 26;9(2):123. | ||||||||||
| Title: | Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway. | ||||||||||
| Author: | Chen, Dongshao|Lin, Xiaoting|Zhang, Cheng|Liu, Zhentao|Chen, Zuhua|Li, Zhongwu|Wang, Jingyuan|Li, Beifang|Hu, Yanting|Dong, Bin|Shen, Lin|Ji, Jiafu|Gao, Jing|Zhang, Xiaotian | ||||||||||
| PMID: | 29374144 | ||||||||||
| 78. | |||||||||||
| Journal: | Biomed Pharmacother. 2018 Feb;98:709-718. | ||||||||||
| Title: | Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy. | ||||||||||
| Author: | Wan, Boshun|Zhu, Junqiu|Chang, Qing|Zhou, Haihua|Shi, Zhan|Min, Li|Cai, YueJiao|Guan, Honggeng | ||||||||||
| PMID: | 29306208 | ||||||||||
| 79. | |||||||||||
| Journal: | BMC Cancer. 2018 Jan 5;18(1):34. | ||||||||||
| Title: | MiR-199a/b-3p inhibits gastric cancer cell proliferation via down-regulating PAK4/MEK/ERK signaling pathway. | ||||||||||
| Author: | Zeng, Bin|Shi, Wei|Tan, Gao | ||||||||||
| PMID: | 29304764 | ||||||||||