Primary Site >> Esophagus Cancer
Gene >> MAP2K7
| 1. | |||||||||||
| Journal: | Oncogene. 2000 Mar 23;19(13):1665-75. | ||||||||||
| Title: | Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway. | ||||||||||
| Author: | Leu, C M|Chang, C|Hu, C | ||||||||||
| PMID: | 10763823 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2001 May 4;276(18):15537-46. Epub 2001 Jan 31. | ||||||||||
| Title: | Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent. | ||||||||||
| Author: | Barry, O P|Mullan, B|Sheehan, D|Kazanietz, M G|Shanahan, F|Collins, J K|O'Sullivan, G C | ||||||||||
| PMID: | 11297525 | ||||||||||
| 3. | |||||||||||
| Journal: | Biochem Pharmacol. 2004 May 1;67(9):1701-10. | ||||||||||
| Title: | Enhancement of peripheral benzodiazepine receptor ligand-induced apoptosis and cell cycle arrest of esophageal cancer cells by simultaneous inhibition of MAPK/ERK kinase. | ||||||||||
| Author: | Sutter, Andreas P|Maaser, Kerstin|Gerst, Bastian|Krahn, Antje|Zeitz, Martin|Scherubl, Hans | ||||||||||
| PMID: | 15081869 | ||||||||||
| 4. | |||||||||||
| Journal: | Anticancer Res. 2004 Mar-Apr;24(2B):811-9. | ||||||||||
| Title: | Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro. | ||||||||||
| Author: | Akimoto, Tetsuo|Nonaka, Tetsuo|Harashima, Koichi|Ishikawa, Hitoshi|Sakurai, Hideyuki|Mitsuhashi, Norio | ||||||||||
| PMID: | 15161032 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2004 Dec 3;279(49):50676-83. Epub 2004 Sep 16. | ||||||||||
| Title: | The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. | ||||||||||
| Author: | Chang, Mei-Chi|Wu, Hui-Lin|Lee, Jang-Jaer|Lee, Po-Hsuen|Chang, Hsiao-Hwa|Hahn, Liang-Jiunn|Lin, Bor-Ru|Chen, Yi-Jane|Jeng, Jiiang-Huei | ||||||||||
| PMID: | 15375172 | ||||||||||
| 6. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2006 Mar 31;342(1):286-92. Epub 2006 Feb 6. | ||||||||||
| Title: | Differentiation-associated genes regulated by TPA-induced c-Jun expression via a PKC/JNK pathway in KYSE450 cells. | ||||||||||
| Author: | Yu, Xinfeng|Luo, Aiping|Zhou, Changchun|Ding, Fang|Wu, Min|Zhan, Qimin|Liu, Zhihua | ||||||||||
| PMID: | 16480952 | ||||||||||
| 7. | |||||||||||
| Journal: | Oral Oncol. 2007 Nov;43(10):1026-33. | ||||||||||
| Title: | Up-regulation of matrix metalloproteinase-8 by betel quid extract and arecoline and its role in 2D motility. | ||||||||||
| Author: | Liu, Shyun-Yeu|Liu, Young-Chau|Huang, Wen-Tsung|Huang, Guan-Cheng|Chen, Tai-Chi|Lin, Mei-Huei | ||||||||||
| PMID: | 17306610 | ||||||||||
| 8. | |||||||||||
| Journal: | J Cell Biochem. 2008 Sep 1;105(1):53-60. | ||||||||||
| Title: | Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation via beta-adrenoceptor-dependent transactivation of extracellular signal-regulated kinase/cyclooxygenase-2 pathway. | ||||||||||
| Author: | Liu, Xuan|Wu, William K K|Yu, Le|Sung, Joseph J Y|Srivastava, Gopesh|Zhang, Shu T|Cho, Chi H | ||||||||||
| PMID: | 18452159 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Biol Rep. 2011 Feb;38(2):865-72. | ||||||||||
| Title: | The expression and activation of ERK/MAPK pathway in human esophageal cancer cell line EC9706. | ||||||||||
| Author: | Zheng, Shu-Tao|Huo, Qi|Tuerxun, Aerziguli|Ma, Wen-Jing|Lv, Guo-Dong|Huang, Cong-Gai|Liu, Qing|Wang, Xing|Lin, Ren-Yong|Sheyhidin, Ilyar|Lu, Xiao-Mei | ||||||||||
| PMID: | 20464500 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2011;6(10):e25806. | ||||||||||
| Title: | BRAF mutations in advanced cancers: clinical characteristics and outcomes. | ||||||||||
| Author: | El-Osta, Hazem|Falchook, Gerald|Tsimberidou, Apostolia|Hong, David|Naing, Aung|Kim, Kevin|Wen, Sijin|Janku, Filip|Kurzrock, Razelle | ||||||||||
| PMID: | 22039425 | ||||||||||
| 11. | |||||||||||
| Journal: | Anticancer Res. 2012 Jul;32(7):2827-34. | ||||||||||
| Title: | Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. | ||||||||||
| Author: | Bao, Xiao-Hong|Takaoka, Munenori|Hao, Hui-Fang|Wang, Zhi-Gang|Fukazawa, Takuya|Yamatsuji, Tomoki|Sakurama, Kazufumi|Sun, Dong-Sheng|Nagasaka, Takeshi|Fujiwara, Toshiyoshi|Naomoto, Yoshio | ||||||||||
| PMID: | 22753744 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Carcinog. 2012 Oct;51(10):796-806. | ||||||||||
| Title: | Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation. | ||||||||||
| Author: | Zare, Maryam|Jazii, Ferdous Rastgar|Soheili, Zahra-Soheila|Moghanibashi, Mohamad-Mehdi | ||||||||||
| PMID: | 22965424 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncol Rep. 2013 Aug;30(2):739-44. | ||||||||||
| Title: | Differentiation of immature DCs into endothelial-like cells in human esophageal carcinoma tissue homogenates. | ||||||||||
| Author: | Lu, Jing|Bai, Ruihua|Qin, Zhenzhu|Zhang, Yanyan|Zhang, Xiaoyan|Jiang, Yanan|Yang, Hongyan|Huang, Youtian|Li, Gang|Zhao, Mingyao|Dong, Ziming | ||||||||||
| PMID: | 23708958 | ||||||||||
| 14. | |||||||||||
| Journal: | Yao Xue Xue Bao. 2013 May;48(5):635-41. | ||||||||||
| Title: | [Roles of targeting Ras/Raf/MEK/ERK signaling pathways in the treatment of esophageal carcinoma]. | ||||||||||
| Author: | Chang, Yu-Sui|Liu, Ji-Chun|Fu, Hua-Qun|Yu, Ben-Tong|Zou, Shu-Bing|Wu, Qi-Cai|Wan, Li | ||||||||||
| PMID: | 23888683 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncol Rep. 2014 Mar;31(3):1296-304. | ||||||||||
| Title: | Overexpression of transferrin receptor CD71 and its tumorigenic properties in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Chan, Kin Tak|Choi, Mei Yuk|Lai, Kenneth K Y|Tan, Winnie|Tung, Lai Nar|Lam, Ho Yu|Tong, Daniel K H|Lee, Nikki P|Law, Simon | ||||||||||
| PMID: | 24435655 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2014 Oct 15;7(11):7663-71. eCollection 2014. | ||||||||||
| Title: | Aquaporin-8 mediates human esophageal cancer Eca-109 cell migration via the EGFR-Erk1/2 pathway. | ||||||||||
| Author: | Chang, Heng|Shi, Yong-Hua|Talaf, Tuo-Kan|Lin, Chen | ||||||||||
| PMID: | 25550802 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Lett. 2014 Dec 1;355(1):34-45. | ||||||||||
| Title: | Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance. | ||||||||||
| Author: | Yu, Le|Gu, Chunping|Zhong, Desheng|Shi, Lili|Kong, Yi|Zhou, Zhitao|Liu, Shuwen | ||||||||||
| PMID: | 25236911 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Mol Sci. 2014 Jul 14;15(7):12422-41. | ||||||||||
| Title: | DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. | ||||||||||
| Author: | Yin, Xiaoran|Zhang, Jun|Li, Xiaoning|Liu, Dong|Feng, Cheng|Liang, Rongrui|Zhuang, Kun|Cai, Chenlei|Xue, Xinghuan|Jing, Fuchun|Wang, Xijing|Wang, Jun|Liu, Xinlian|Ma, Hongbing | ||||||||||
| PMID: | 25026173 | ||||||||||
| 19. | |||||||||||
| Journal: | Am Soc Clin Oncol Educ Book. 2014:e172-8. | ||||||||||
| Title: | New directions in perioperative management of locally advanced esophagogastric cancer. | ||||||||||
| Author: | Burtness, Barbara|Ilson, David|Iqbal, Syma | ||||||||||
| PMID: | 24857100 | ||||||||||
| 20. | |||||||||||
| Journal: | Invest New Drugs. 2015 Jun;33(3):641-51. | ||||||||||
| Title: | Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors. | ||||||||||
| Author: | Nakamichi, Shinji|Nokihara, Hiroshi|Yamamoto, Noboru|Yamada, Yasuhide|Fujiwara, Yutaka|Tamura, Yosuke|Wakui, Hiroshi|Honda, Kazunori|Mizugaki, Hidenori|Kitazono, Satoru|Tanabe, Yuko|Asahina, Hajime|Yamazaki, Naoya|Suzuki, Shigenobu|Matsuoka, Mieko|Ogita, | ||||||||||
| PMID: | 25809858 | ||||||||||
| 21. | |||||||||||
| Journal: | BMC Cancer. 2015 Jun 4;15:454. | ||||||||||
| Title: | Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma. | ||||||||||
| Author: | Gavine, Paul R|Wang, Mei|Yu, Dehua|Hu, Eva|Huang, Chunlei|Xia, Jenny|Su, Xinying|Fan, Joan|Zhang, Tianwei|Ye, Qingqing|Zheng, Li|Zhu, Guanshan|Qian, Ziliang|Luo, Qingquan|Hou, Ying Yong|Ji, Qunsheng | ||||||||||
| PMID: | 26040563 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2015 Dec 8;6(39):42183-96. | ||||||||||
| Title: | Mutant HRAS as novel target for MEK and mTOR inhibitors. | ||||||||||
| Author: | Kiessling, Michael K|Curioni-Fontecedro, Alessandra|Samaras, Panagiotis|Atrott, Kirstin|Cosin-Roger, Jesus|Lang, Silvia|Scharl, Michael|Rogler, Gerhard | ||||||||||
| PMID: | 26544513 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2016 Jan;77(1):99-108. | ||||||||||
| Title: | A phase I study of two dosing schedules of oral BI 847325 in patients with advanced solid tumors. | ||||||||||
| Author: | Schoffski, Patrick|Aftimos, Philippe|Dumez, Herlinde|Deleporte, Amelie|De Block, Katrien|Costermans, Jo|Billiet, Maureen|Meeus, Marie-Anne|Lee, Chooi|Schnell, David|Goeldner, Rainer-Georg|Awada, Ahmad | ||||||||||
| PMID: | 26650227 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncol Lett. 2016 Nov;12(5):3598-3608. Epub 2016 Sep 5. | ||||||||||
| Title: | Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. | ||||||||||
| Author: | Lu, Qiu-Ping|Chen, Wen-Dan|Peng, Jie-Ren|Xu, Yao-Dong|Cai, Qian|Feng, Gong-Kan|Ding, Ke|Zhu, Xiao-Feng|Guan, Zhong | ||||||||||
| PMID: | 27900042 | ||||||||||
| 25. | |||||||||||
| Journal: | J Cell Biochem. 2017 Aug 31. | ||||||||||
| Title: | FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Shi, Yuanyuan|Liu, Xuejiao|Fredimoses, Mangaladoss|Song, Mengqiu|Chen, Hanyong|Liu, Kangdong|Lee, Mee-Hyun|Dong, Zigang | ||||||||||
| PMID: | 28857247 | ||||||||||
| 26. | |||||||||||
| Journal: | Drug Deliv. 2017 Nov;24(1):1549-1564. | ||||||||||
| Title: | GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways. | ||||||||||
| Author: | Pi, Jiang|Jiang, Jinhuan|Cai, Huaihong|Yang, Fen|Jin, Hua|Yang, Peihui|Cai, Jiye|Chen, Zheng W | ||||||||||
| PMID: | 29019267 | ||||||||||
| 27. | |||||||||||
| Journal: | Molecules. 2018 Apr 17;23(4). pii: molecules23040930. | ||||||||||
| Title: | Chemoresistance to Cancer Treatment: Benzo-alpha-Pyrene as Friend or Foe? | ||||||||||
| Author: | Dzobo, Kevin|Hassen, Naseeha|Senthebane, Dimakatso Alice|Thomford, Nicholas Ekow|Rowe, Arielle|Shipanga, Hendrina|Wonkam, Ambroise|Parker, M Iqbal|Mowla, Shaheen|Dandara, Collet | ||||||||||
| PMID: | 29673198 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Res. 2018 Sep 1;78(17):4957-4970. | ||||||||||
| Title: | IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment. | ||||||||||
| Author: | Karakasheva, Tatiana A|Lin, Eric W|Tang, Qiaosi|Qiao, Edmund|Waldron, Todd J|Soni, Monica|Klein-Szanto, Andres J|Sahu, Varun|Basu, Devraj|Ohashi, Shinya|Baba, Kiichiro|Giaccone, Zachary T|Walker, Sarah R|Frank, David A|Wileyto, E Paul|Long, Qi|Dunagin, Ma | ||||||||||
| PMID: | 29976575 | ||||||||||