Primary Site >> Pancreatic Cancer
Gene >> MAP2K4
| 1. | |||||||||||
| Journal: | Cancer Res. 1997 Oct 1;57(19):4177-82. | ||||||||||
| Title: | Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. | ||||||||||
| Author: | Teng, D H|Perry, W L 3rd|Hogan, J K|Baumgard, M|Bell, R|Berry, S|Davis, T|Frank, D|Frye, C|Hattier, T|Hu, R|Jammulapati, S|Janecki, T|Leavitt, A|Mitchell, J T|Pero, R|Sexton, D|Schroeder, M|Su, P H|Swedlund, B|Kyriakis, J M|Avruch, J|Bartel, P|Wong, A K|T | ||||||||||
| PMID: | 9331070 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 1998 Jun 1;58(11):2339-42. | ||||||||||
| Title: | Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. | ||||||||||
| Author: | Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E | ||||||||||
| PMID: | 9622070 | ||||||||||
| 3. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:4-8. | ||||||||||
| Title: | Progress in cancer genetics: lessons from pancreatic cancer. | ||||||||||
| Author: | Goggins, M|Kern, S E|Offerhaus, J A|Hruban, R H | ||||||||||
| PMID: | 10436774 | ||||||||||
| 4. | |||||||||||
| Journal: | Curr Opin Gastroenterol. 2000 Sep;16(5):419-25. | ||||||||||
| Title: | Molecular genetics of ductal pancreatic neoplasia. | ||||||||||
| Author: | Su, G H|Kern, S E | ||||||||||
| PMID: | 17031113 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2002 Jul 1;62(13):3789-93. | ||||||||||
| Title: | Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. | ||||||||||
| Author: | Murphy, Kathleen M|Brune, Kieran A|Griffin, Constance|Sollenberger, Jennifer E|Petersen, Gloria M|Bansal, Ravi|Hruban, Ralph H|Kern, Scott E | ||||||||||
| PMID: | 12097290 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2004 Aug 5;23(35):5978-85. | ||||||||||
| Title: | Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors. | ||||||||||
| Author: | Wang, Lei|Pan, Yong|Dai, Jia Le | ||||||||||
| PMID: | 15184866 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Cancer Res. 2004 Dec 15;10(24):8516-20. | ||||||||||
| Title: | MAP2K4/MKK4 expression in pancreatic cancer: genetic validation of immunohistochemistry and relationship to disease course. | ||||||||||
| Author: | Xin, Wei|Yun, Ki J|Ricci, Francesca|Zahurak, Marianna|Qiu, Wanglong|Su, Gloria H|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Iacobuzio-Donahue, Christine A | ||||||||||
| PMID: | 15623633 | ||||||||||
| 8. | |||||||||||
| Journal: | Arch Pathol Lab Med. 2009 Mar;133(3):413-22. | ||||||||||
| Title: | The pathology and genetics of metastatic pancreatic cancer. | ||||||||||
| Author: | Yachida, Shinichi|Iacobuzio-Donahue, Christine A | ||||||||||
| PMID: | 19260747 | ||||||||||
| 9. | |||||||||||
| Journal: | BMC Cancer. 2010 Aug 19;10:440. | ||||||||||
| Title: | Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells. | ||||||||||
| Author: | Kreutzer, Jan N|Ruzzene, Maria|Guerra, Barbara | ||||||||||
| PMID: | 20718998 | ||||||||||
| 10. | |||||||||||
| Journal: | J Cell Physiol. 2010 May;223(2):309-16. | ||||||||||
| Title: | Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. | ||||||||||
| Author: | Kisfalvi, Krisztina|Hurd, Cliff|Guha, Sushovan|Rozengurt, Enrique | ||||||||||
| PMID: | 20082306 | ||||||||||
| 11. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5934-41. | ||||||||||
| Title: | Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. | ||||||||||
| Author: | Mann, Karen M|Ward, Jerrold M|Yew, Christopher Chin Kuan|Kovochich, Anne|Dawson, David W|Black, Michael A|Brett, Benjamin T|Sheetz, Todd E|Dupuy, Adam J|Chang, David K|Biankin, Andrew V|Waddell, Nicola|Kassahn, Karin S|Grimmond, Sean M|Rust, Alistair G|Ad | ||||||||||
| PMID: | 22421440 | ||||||||||
| 12. | |||||||||||
| Journal: | Antioxid Redox Signal. 2012 Nov 15;17(10):1417-32. | ||||||||||
| Title: | Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis. | ||||||||||
| Author: | Pramanik, Kartick C|Srivastava, Sanjay K | ||||||||||
| PMID: | 22530568 | ||||||||||
| 13. | |||||||||||
| Journal: | Nature. 2012 Nov 15;491(7424):399-405. | ||||||||||
| Title: | Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. | ||||||||||
| Author: | Biankin, Andrew V|Waddell, Nicola|Kassahn, Karin S|Gingras, Marie-Claude|Muthuswamy, Lakshmi B|Johns, Amber L|Miller, David K|Wilson, Peter J|Patch, Ann-Marie|Wu, Jianmin|Chang, David K|Cowley, Mark J|Gardiner, Brooke B|Song, Sarah|Harliwong, Ivon|Idrisog | ||||||||||
| PMID: | 23103869 | ||||||||||
| 14. | |||||||||||
| Journal: | Carcinogenesis. 2013 May;34(5):1001-5. | ||||||||||
| Title: | Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer. | ||||||||||
| Author: | Huang, Liming|Wu, Chen|Yu, Dianke|Wang, Chengfeng|Che, Xu|Miao, Xiaoping|Zhai, Kan|Chang, Jiang|Jiang, Guoliang|Yang, Xianghong|Cao, Guangwen|Hu, Zhibin|Zhou, Yongjian|Zuo, Chaohui|Wang, Chunyou|Zhang, Xianghong|Zhou, Yifeng|Yu, Xianjun|Dai, Wanjin|Li, Zh | ||||||||||
| PMID: | 23299404 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncogene. 2014 Jan 23;33(4):514-24. | ||||||||||
| Title: | Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1. | ||||||||||
| Author: | Wang, P|Chen, L|Zhang, J|Chen, H|Fan, J|Wang, K|Luo, J|Chen, Z|Meng, Z|Liu, L | ||||||||||
| PMID: | 23334332 | ||||||||||
| 16. | |||||||||||
| Journal: | Dig Dis Sci. 2014 Jul;59(7):1452-60. | ||||||||||
| Title: | LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. | ||||||||||
| Author: | Liu, Jianhui|Xu, Dong|Wang, Qingguang|Zheng, Datong|Jiang, Xiuqin|Xu, Lijian | ||||||||||
| PMID: | 24532253 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2014 Jun 15;74(12):3344-56. | ||||||||||
| Title: | Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Davies, Clare C|Harvey, Emma|McMahon, Raymond F T|Finegan, Katherine G|Connor, Frances|Davis, Roger J|Tuveson, David A|Tournier, Cathy | ||||||||||
| PMID: | 24713432 | ||||||||||
| 18. | |||||||||||
| Journal: | Nature. 2017 Feb 16;542(7641):362-366. | ||||||||||
| Title: | Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. | ||||||||||
| Author: | Genovese, Giannicola|Carugo, Alessandro|Tepper, James|Robinson, Frederick Scott|Li, Liren|Svelto, Maria|Nezi, Luigi|Corti, Denise|Minelli, Rosalba|Pettazzoni, Piergiorgio|Gutschner, Tony|Wu, Chia-Chin|Seth, Sahil|Akdemir, Kadir Caner|Leo, Elisabetta|Amin, | ||||||||||
| PMID: | 28178232 | ||||||||||