Primary Site >> Pancreatic Cancer
Gene >> MAP2K4
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Ref: Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. PMID: 9331070 |
Ref: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. PMID: 9622070 |
Ref: Progress in cancer genetics: lessons from pancreatic cancer. PMID: 10436774 |
Ref: Molecular genetics of ductal pancreatic neoplasia. PMID: 17031113 |
Ref: Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. PMID: 12097290 |
Ref: Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors. PMID: 15184866 Ref: MAP2K4/MKK4 expression in pancreatic cancer: genetic validation of immunohistochemistry and relationship to disease course. PMID: 15623633 |
Ref: The pathology and genetics of metastatic pancreatic cancer. PMID: 19260747 |
Ref: Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. PMID: 20082306 Ref: Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells. PMID: 20718998 |
Ref: Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. PMID: 22421440 Ref: Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis. PMID: 22530568 Ref: Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. PMID: 23103869 |
Ref: Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer. PMID: 23299404 |
Ref: Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1. PMID: 23334332 Ref: LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. PMID: 24532253 Ref: Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. PMID: 24713432 |
Ref: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. PMID: 28178232 |